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Genome Information for Macaca mulatta
We used Chromium Single Cell Multiome ATAC + Gene Expression to analyze CD45+ leukocytes in the rhesus macaque brain during homeostasis and chronic SIV infection
Overall design: Leukocytes (CD45+ cells) of previously cryopreserved rhesus macaque brain single cell suspensions were isolated using MACS CD45 microbeads/column purification followed by Fluorescence-activated cell sorting (FACS) according to the presence of absence of CD45 signal. Nuclei were extracted according to 10x protocols and analyzed using single snATACseq
Accession | PRJNA1089650; GEO: GSE261968 |
Scope | Multiisolate |
Organism | Macaca mulatta[Taxonomy ID: 9544] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca; Macaca mulatta |
Publications | Elizaldi SR et al., "Chronic SIV-Induced neuroinflammation disrupts CCR7+ CD4+ T cell immunosurveillance in the rhesus macaque brain.", J Clin Invest, 2024 Mar 12;134(9) |
Submission | Registration date: 19-Mar-2024 Iyer Lab, Immunology, University of California Davis |
Relevance | Model Organism |
Project Data:
Resource Name | Number of Links |
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Sequence data |
SRA Experiments | 8 |
Publications |
PubMed | 1 |
PMC | 1 |
Other datasets |
BioSample | 8 |
GEO DataSets | 1 |