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Accession: PRJNA1081354 ID: 1081354

Fibrosis-related transcriptome unveils a distinctive matrix remodeling pattern in penetrating but not in stricturing ileal Crohn's disease (human)

See Genome Information for Homo sapiens
Using Nanostring technology and comparative bioinformatics, we analyzed the expression of 760 fibrosis-related genes in 36 ileal surgical specimens, 12 B2(Penetrating) and 24 B3(structuring), the latter including 12 cases with associated stricture(s) (B3s) and 12 without (B3o). Overall design: nCounter® Fibrosis Consortium Panel was runned in 36 ileal surgical specimens
AccessionPRJNA1081354; GEO: GSE259353
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsTavares de Sousa H et al., "Fibrosis-related Transcriptome Unveils a Distinctive Remodelling Matrix Pattern in Penetrating Ileal Crohn's Disease.", J Crohns Colitis, 2024 Nov 4;18(11):1741-1752
SubmissionRegistration date: 27-Feb-2024
Expression Regulation in Cancer, ipatimup/i3s
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots27360
Data volume, Processed Mbytes1
Data volume, Supplementary Mbytes1

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