BioProject

Clostridioides difficile (C. difficile) is a pathogen that causes pseudomembranous colitis with antibiotic-associated diarrhea. More...

Clostridioides difficile (C. difficile) is a pathogen that causes pseudomembranous colitis with antibiotic-associated diarrhea. The epidemiology and molecular evolution of C. difficile may differ among different geographic regions, and mining its genomic information can help us understand the epidemiology and molecular evolution of C. difficile, as well as focus on its mode of transmission, which is one of the effective means to prevent and control Clostridioides difficile infection (CDI). In this study, a strain of C. difficile was isolated from a patient in the ICU of the Affiliated Hospital of Guizhou Medical University in China, and its surface morphology was observed by scanning electron microscopy while its growth characteristics were recorded. The whole genome of the strain was sequenced using the Illumina HiSeq platform, and the sequencing results were analyzed. Less...