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Accession: PRJNA1023888 ID: 1023888

Down-regulation of N4-acetylcytidine modification in myeloid cells attenuates immunotherapy and exacerbates hepatocellular carcinoma progression (house mouse)

See Genome Information for Mus musculus
To resolve the patterns of TILs in HCC, we performed scRNA-seq on the TILs isolated from the three groups (P: control group, T: immunotherapy group, TR: immunotherapy plus REM group; n=2 per group) at two time points (1 w and 2 w) Overall design: Comparative gene expression profiling analysis of single-cell RNA-seq data for the TILs isolated from tumor of mice hepatocellular carcinoma orthotopic transplantation model.
AccessionPRJNA1023888; GEO: GSE244613
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsXu N et al., "Downregulation of N4-acetylcytidine modification in myeloid cells attenuates immunotherapy and exacerbates hepatocellular carcinoma progression.", Br J Cancer, 2024 Feb;130(2):201-212
SubmissionRegistration date: 4-Oct-2023
Zhejiang University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes9759
SRA Data Details
ParameterValue
Data volume, Gbases1,413
Data volume, Tbytes0.49

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