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Conserved domains on  [gi|1011058299|ref|YP_009240664|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Octopus conispadiceus]

Protein Classification

H(+)-translocating NADH:ubiquinone reductase subunit 2( domain architecture ID 11475920)

H(+)-translocating NADH:ubiquinone reductase subunit 2, a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 4-336 4.62e-66

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 211.28  E-value: 4.62e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   4 KFFPSNFMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLY 83
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  84 SFSTFSMfnntfmsSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSF---INFNYIIIIMCSLT 160
Cdd:MTH00144   81 SFSWFSM-------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNfldLYWLAYLLCVISVL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 161 SAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMnKQ 240
Cdd:MTH00144  154 SALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSY-KT 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 241 NIFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIKSFFLLNINKMKMTTKSI 320
Cdd:MTH00144  233 GLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSI 312

                         330
                  ....*....|....*.
gi 1011058299 321 MCLNMMSTIIFIPMMM 336
Cdd:MTH00144  313 ISLNLLGGLLFLLLYL 328
 
Name Accession Description Interval E-value
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 4-336 4.62e-66

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 211.28  E-value: 4.62e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   4 KFFPSNFMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLY 83
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  84 SFSTFSMfnntfmsSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSF---INFNYIIIIMCSLT 160
Cdd:MTH00144   81 SFSWFSM-------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNfldLYWLAYLLCVISVL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 161 SAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMnKQ 240
Cdd:MTH00144  154 SALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSY-KT 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 241 NIFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIKSFFLLNINKMKMTTKSI 320
Cdd:MTH00144  233 GLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSI 312

                         330
                  ....*....|....*.
gi 1011058299 321 MCLNMMSTIIFIPMMM 336
Cdd:MTH00144  313 ISLNLLGGLLFLLLYL 328
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-303 2.11e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 91.72  E-value: 2.11e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELN------LMGILplmniKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLY 83
Cdd:COG1007   105 YALLLFATLGMMLMASANDLLTLFLGLELLslslyvLVAFR-----RDDRRSSEAALKYFLLGALSSGFLLYGISLLYGA 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  84 SFST------FSMFNNTFMSSIMMLSLLI-------KLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFML------ 144
Cdd:COG1007   180 TGSLnlagiaAALAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllve 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 145 ---SFINFNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTL----MFLYLLIYSMIIFPLFI 217
Cdd:COG1007   260 afpGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFA 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 218 NMNYYSNHSTYSLTEQNYN-MNKQN----IFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYF 292
Cdd:COG1007   340 VILLLSRKGGEAEEIEDLAgLARRSpllaLAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYY 419

                         330
                  ....*....|.
gi 1011058299 293 YLNLTMMMMIK 303
Cdd:COG1007   420 YLRVVKAMYFD 430
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 26-286 2.48e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 83.90  E-value: 2.48e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  26 SSHWLMMWMGLELNLMGILPLMNIKTKN-FEIESSMKYFIIQSLSSSLFIMTMIIMYLYSFST------------FSMFN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSpRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLsfdelskaltggLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  93 NTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISW-MTLYLILTWQKLAP-------LFMLSFINFNYIIIIMCSLTSAIL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGyglirrsLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 165 GSIQAINQSSLQMIMVYSSISHLGWMLCSCSINN----TLMFLYLLIY---SMIIFPLFINMNYYSNHSTYSLTEQNYNM 237
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTiygiQAAIFHLLTHglfSAGLFLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1011058299 238 NKQNIFIIMLI--LSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMST 286
Cdd:pfam00361 241 TMPILALVFLVamLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 10-300 6.21e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.53  E-value: 6.21e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKN-FEIESSMKYFIIQSLSSSLFIMTMIIMYLYS---- 84
Cdd:TIGR01770 105 YILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGLKRKSrFSTEAGLKYFILGAFSSGLLLFGISLIYGFTgsln 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  85 ------FSTFSMFNNT--FMSSIMMLS-LLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFML---------SF 146
Cdd:TIGR01770 185 fedlllFLSNGMLNISllLLGIVLILVgLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFlrlflyilfGF 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 147 INFNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTL----MFLYLLIY---SMIIFPLFINM 219
Cdd:TIGR01770 265 SEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYalmSLGAFGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 220 NYYSNHSTYSLTEQnYNMNKQNIFIIMLIL----SLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLN 295
Cdd:TIGR01770 345 RSYKDEWIEYISDF-AGLFKTNPILAILILifmfSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ....*
gi 1011058299 296 LTMMM 300
Cdd:TIGR01770 424 VVKVM 428
 
Name Accession Description Interval E-value
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 4-336 4.62e-66

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 211.28  E-value: 4.62e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   4 KFFPSNFMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLY 83
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  84 SFSTFSMfnntfmsSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSF---INFNYIIIIMCSLT 160
Cdd:MTH00144   81 SFSWFSM-------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNfldLYWLAYLLCVISVL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 161 SAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMnKQ 240
Cdd:MTH00144  154 SALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSY-KT 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 241 NIFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIKSFFLLNINKMKMTTKSI 320
Cdd:MTH00144  233 GLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSI 312

                         330
                  ....*....|....*.
gi 1011058299 321 MCLNMMSTIIFIPMMM 336
Cdd:MTH00144  313 ISLNLLGGLLFLLLYL 328
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 5-339 7.89e-66

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 210.84  E-value: 7.89e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   5 FFPSNFMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLys 84
Cdd:MTH00160    3 MNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML-- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  85 fstFSMFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSFINFNYIIIIMcSLTSAIL 164
Cdd:MTH00160   81 ---NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIII-IILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 165 GSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIFI 244
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 245 IMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIKSFFLLNINKMKMTTKSIMCLN 324
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*
gi 1011058299 325 MMSTIIFIPMMMYAM 339
Cdd:MTH00160  317 FLSFISLFGLILSSL 331
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 11-336 2.16e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 168.49  E-value: 2.16e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  11 MFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLYSFS-TFS 89
Cdd:MTH00105    8 IIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQwTIT 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  90 MFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSFINFNYIIIIMC--SLTSAILGSI 167
Cdd:MTH00105   88 KLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLtlAILSILIGGW 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 168 QAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIFIIML 247
Cdd:MTH00105  168 GGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLT 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 248 ILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIKSFFLLNINKMKMTTKSIMCLNMMS 327
Cdd:MTH00105  248 LLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTKPMTLLP 327


                  ....*....
gi 1011058299 328 TIIFIPMMM 336
Cdd:MTH00105  328 TLIILSTML 336
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 8-302 9.94e-42

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 148.43  E-value: 9.94e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   8 SNFMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLYSFS- 86
Cdd:MTH00112    5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQw 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  87 TFSMFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAP--LFMLSFINFNYIIIIMCSLTSAIL 164
Cdd:MTH00112   85 DITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPltLLLMTSNSLNPTLLLTLAILSTLI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 165 GSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIFI 244
Cdd:MTH00112  165 GGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTL 244

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1011058299 245 IMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMI 302
Cdd:MTH00112  245 MLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTI 302
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-342 1.14e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 145.83  E-value: 1.14e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIM-TMIIMYLYSFSTF 88
Cdd:MTH00070    7 SILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFsSTINAWFTGEWTI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  89 SMFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAP---LFMLSFINFNYIIIIMcSLTSAILG 165
Cdd:MTH00070   87 MNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPmalLIQISHLLNSNLLIIM-GLLSTLIG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 166 SIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIFII 245
Cdd:MTH00070  166 GWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMM 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 246 MLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIKSFFLLNINK----MKMTTKSIM 321
Cdd:MTH00070  246 LTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKlywrFKNKTNNLL 325

                         330       340
                  ....*....|....*....|.
gi 1011058299 322 CLNMMSTIIFIPMMMYAMNIL 342
Cdd:MTH00070  326 SLTIILSLMLLPITPTILNLF 346
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 10-336 1.81e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 142.12  E-value: 1.81e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYlysfstFS 89
Cdd:MTH00197    1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSF------SN 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  90 MFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSFINFNYIIIIMCSLTSAILGSIQA 169
Cdd:MTH00197   75 LYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 170 INQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIFIIMLIL 249
Cdd:MTH00197  155 MNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFL 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 250 SLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIKSFFLLNINKMK--MTTKSIMCLNMMS 327
Cdd:MTH00197  235 SLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKInlLYSGLFILLMMML 314


                  ....*....
gi 1011058299 328 TIIFIPMMM 336
Cdd:MTH00197  315 PLLMIFTMI 323
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 10-297 2.14e-39

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 142.38  E-value: 2.14e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMII-MYLYSFSTF 88
Cdd:MTH00041    7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIqAWLSGSWSI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  89 SMFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSFI--NFNYIIIIMCSLTSAILGS 166
Cdd:MTH00041   87 NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsnLLNSNILILCGILSVLVGG 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 167 IQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIFIIM 246
Cdd:MTH00041  167 WGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFIL 246

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1011058299 247 LILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLT 297
Cdd:MTH00041  247 SILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRIS 297
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-330 2.53e-39

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 141.84  E-value: 2.53e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   6 FPSNFMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYlysf 85
Cdd:MTH00011    5 FPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMW---- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  86 sTFSMFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSFINFNYIIIIMCSL--TSAI 163
Cdd:MTH00011   81 -SFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMaaMSAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 164 LGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIF 243
Cdd:MTH00011  160 AGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMS 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 244 IIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIKSFFLLNINKMKMTTKSIMCL 323
Cdd:MTH00011  240 LFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPTFSSLKSAPYEPKTKILI 319


                  ....*..
gi 1011058299 324 NMMSTII 330
Cdd:MTH00011  320 SMCTLSL 326
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 18-301 3.01e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 139.17  E-value: 3.01e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  18 LGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSlssslfimTMIIMYLYSFST---------F 88
Cdd:MTH00135   15 LGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQA--------TAAAMILFASTTnawltgqwdI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  89 SMFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPL-FMLSFINFNYIIIIMCSLTSAILGSI 167
Cdd:MTH00135   87 QQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFaLILQIAPTNPTLLITLGLTSTLVGGW 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 168 QAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIFIIML 247
Cdd:MTH00135  167 GGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLI 246

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1011058299 248 ILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMM 301
Cdd:MTH00135  247 LLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMT 300
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 11-302 9.03e-34

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 127.39  E-value: 9.03e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  11 MFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLYSF-STFS 89
Cdd:MTH00200    8 LFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGqWGIS 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  90 MFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSFINFNYIIIIM--CSLTSAILGSI 167
Cdd:MTH00200   88 EMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILllLGLLSVLVGGW 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 168 QAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYNMNKQNIFIIML 247
Cdd:MTH00200  168 GGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLT 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1011058299 248 ILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMI 302
Cdd:MTH00200  248 LLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLL 302
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-303 2.11e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 91.72  E-value: 2.11e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELN------LMGILplmniKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLY 83
Cdd:COG1007   105 YALLLFATLGMMLMASANDLLTLFLGLELLslslyvLVAFR-----RDDRRSSEAALKYFLLGALSSGFLLYGISLLYGA 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  84 SFST------FSMFNNTFMSSIMMLSLLI-------KLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFML------ 144
Cdd:COG1007   180 TGSLnlagiaAALAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllve 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 145 ---SFINFNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTL----MFLYLLIYSMIIFPLFI 217
Cdd:COG1007   260 afpGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFA 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 218 NMNYYSNHSTYSLTEQNYN-MNKQN----IFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYF 292
Cdd:COG1007   340 VILLLSRKGGEAEEIEDLAgLARRSpllaLAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYY 419

                         330
                  ....*....|.
gi 1011058299 293 YLNLTMMMMIK 303
Cdd:COG1007   420 YLRVVKAMYFD 430
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 15-313 3.48e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 87.39  E-value: 3.48e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  15 MMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKN-FEIESSMKYFIIQSLSSSLFI--------------MTMII 79
Cdd:MTH00196    1 MVALGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLfgcallcgttgglhLSYIN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  80 MYLYSFSTFSMFNNTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSFINFNYIIIIMCSL 159
Cdd:MTH00196   81 LVLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 160 TSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINN------TLMFLYL-LIYSMIIFPLFINMNYYSNHsTYSLTE 232
Cdd:MTH00196  161 FSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiqaSLVYLFIyIIMSICVFSIILALNVYKNL-IIEFSG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 233 QNYNMNKQNIFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMI-KSFFLLNIN 311
Cdd:MTH00196  240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIVKILFFqANSFLLIST 319


                  ..
gi 1011058299 312 KM 313
Cdd:MTH00196  320 KI 321
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 6-296 2.37e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 85.45  E-value: 2.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   6 FPSNFMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKN-FEIESSMKYFIIQSLSSSLFIMTMIIMYLYS 84
Cdd:MTH00199   96 GQSSPILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSaYSTEAGLKYFVLGAVSSGLFLFGCALLYGLT 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  85 FSTFSMFNNTFMSS-----IMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFMLSFINFNYIIIIMCSL 159
Cdd:MTH00199  176 GETSIQGINSILTGdvgkiLITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAV 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 160 TSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINN----TLMFLYLLIY---SMIIFPLFINMNyysnhSTYSLTE 232
Cdd:MTH00199  256 LSIIYGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYvimSICSFSIILSLK-----LTKGLIV 330

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1011058299 233 QNYNMNKQN----IFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNL 296
Cdd:MTH00199  331 EVSGLSRKNpviaLTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 26-286 2.48e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 83.90  E-value: 2.48e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  26 SSHWLMMWMGLELNLMGILPLMNIKTKN-FEIESSMKYFIIQSLSSSLFIMTMIIMYLYSFST------------FSMFN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSpRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLsfdelskaltggLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  93 NTFMSSIMMLSLLIKLGSSPFHMWLPAMCKHISW-MTLYLILTWQKLAP-------LFMLSFINFNYIIIIMCSLTSAIL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGyglirrsLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 165 GSIQAINQSSLQMIMVYSSISHLGWMLCSCSINN----TLMFLYLLIY---SMIIFPLFINMNYYSNHSTYSLTEQNYNM 237
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTiygiQAAIFHLLTHglfSAGLFLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1011058299 238 NKQNIFIIMLI--LSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMST 286
Cdd:pfam00361 241 TMPILALVFLVamLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
10-300 4.93e-18

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 84.87  E-value: 4.93e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELN---LMGILPLMNIKTKNFEieSSMKYFIIQSLSSSLFIMTMIIMYLYSFS 86
Cdd:PRK05777  106 YLLVLFALLGMMVMVSANDLLTLFLGLELLslpLYALAALRRDRRRSLE--AAIKYFVLGALASGFLLYGMSLLYGATGS 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  87 T-----FSMFNNTFMSSIMML--------SLLIKLGSSPFHMWLP--------------AMCKHISWMTLYLiltwqKLA 139
Cdd:PRK05777  184 LsfagiAKALADGSGNSLLLLfglvfllvGLAFKLSAVPFHMWTPdvyegaptpvtaflATAPKIAAFAVLL-----RLL 258

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 140 PLFMLSFINFNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTL----MFLYLLIYSMIIFPL 215
Cdd:PRK05777  259 VVAFGGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTLGA 338

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 216 FINMNYYSNHSTYSLTEQNYN-MNKQN----IFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISL 290
Cdd:PRK05777  339 FGVISLLRRKGGEAESISDFAgLSKRSpllaAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGA 418

                         330
                  ....*....|
gi 1011058299 291 YFYLNLTMMM 300
Cdd:PRK05777  419 FYYLRVIKLM 428
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 10-300 6.21e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 81.53  E-value: 6.21e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKN-FEIESSMKYFIIQSLSSSLFIMTMIIMYLYS---- 84
Cdd:TIGR01770 105 YILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGLKRKSrFSTEAGLKYFILGAFSSGLLLFGISLIYGFTgsln 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  85 ------FSTFSMFNNT--FMSSIMMLS-LLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFML---------SF 146
Cdd:TIGR01770 185 fedlllFLSNGMLNISllLLGIVLILVgLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFlrlflyilfGF 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 147 INFNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTL----MFLYLLIY---SMIIFPLFINM 219
Cdd:TIGR01770 265 SEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYalmSLGAFGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 220 NYYSNHSTYSLTEQnYNMNKQNIFIIMLIL----SLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLN 295
Cdd:TIGR01770 345 RSYKDEWIEYISDF-AGLFKTNPILAILILifmfSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ....*
gi 1011058299 296 LTMMM 300
Cdd:TIGR01770 424 VVKVM 428
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 2-296 4.96e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 63.72  E-value: 4.96e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   2 NNKFFPSNFMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPL---------MNIKTKNFEIESSMKYFIIQSLSSSL 72
Cdd:MTH00198  183 NERGPRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGF 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  73 FIMTMIIMYLYSFSTFSMfnNTFMSSIM-----------------MLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTW 135
Cdd:MTH00198  263 YLFGCALYFGFTGNEGML--GTILSATLettnielrqgslgylfiTVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAII 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 136 QKLAPLFMLSFINFNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINN----TLMFLYLLIYSMI 211
Cdd:MTH00198  341 PKFTVYILLTSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTyeslQASWTYAVTYLVS 420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 212 IFPLFINMNYYSNHSTYSLTEQ-------NYNMNKQNIFIIML--------------ILSLGGMPPMMGFLSKLMILYMM 270
Cdd:MTH00198  421 ALASFTVICTLEEFGTRTPTSRqrdgsfgNYNLVRRLVDLTILsrgqpyiafslaivFLSLAGIPPLLGFLGKWFILVGS 500

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1011058299 271 TKLNM-------LMLPLILFMSTLISLYFYLNL 296
Cdd:MTH00198  501 IKIAFssslsiyYLVALFAIICTCISAFYYIRI 533
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-291 6.38e-10

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 60.16  E-value: 6.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  10 FMFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYlYSFSTFS 89
Cdd:COG0651   110 YPLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLY-GATGTLN 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  90 M---------FNNTFMSSIMMLSLL---IKLGSSPFHMWLP----------------AMCKhiswMTLYLILTWQKLapL 141
Cdd:COG0651   189 MadlaarlaeLDPGLLLAAFALLLVgfgIKAALFPLHFWLPdaypaapspvsallsgLLTK----VGVYAILRVLTL--L 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 142 FMLSFINFNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMF----LYLLIYSMIIFPLFI 217
Cdd:COG0651   263 FGADPALFLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLagalFHLLNHALAKALLFL 342

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1011058299 218 N----MNYYSNHSTYSLTEQNYNMNKQNIFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLY 291
Cdd:COG0651   343 AagaiERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLA 420
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
161-303 7.45e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 56.98  E-value: 7.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 161 SAILGSIQAINQSSLQMIMVYSSISHLGW----MLCSCSINNTLMFLYLLIYsmiifpLFINMNYYSNHSTYSL---TEQ 233
Cdd:PRK02504  286 SMVLGNVVALAQTSMKRMLAYSSIGQAGFvmigLVAGTEAGYASMVFYLLAY------LFMNLGAFACVILFSLrtgTDQ 359

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1011058299 234 --NYNMNKQNIFIIML-----ILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIK 303
Cdd:PRK02504  360 isDYAGLYQKDPLLTLglslcLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRVIKMMVVK 436
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 11-289 2.25e-07

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 52.31  E-value: 2.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  11 MFMIMMILGTIMSLSSSHWLMMWMGLELNLMGILpLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYlYSFSTFS- 89
Cdd:PRK08668  102 MFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSF-MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIFLIY-AKTGTFDf 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  90 ------MFNNTFMSSIMMLSLLI------KLGSSPFHMWLP-------------------AMCKHISWMTLYLILTWQKL 138
Cdd:PRK08668  180 adisqgLINDTSTGFALIVFLFLlafgvaKAGIFPLHVWAPdayseapqsfsavlsgqlsKLGAYGFLLVLYVLPGTKLF 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 139 APLFMLSFINFNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMFLYLL-------IYSMI 211
Cdd:PRK08668  260 SEFGTYRGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGGLfhvfnhaLFKGL 339

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1011058299 212 IFPLFINMNYYSNHSTYS-LTEQNYNMNKQNIFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLIS 289
Cdd:PRK08668  340 FFLIFAAVIYRTGTTKISeMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGS 418
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 99-290 2.76e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 45.64  E-value: 2.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  99 IMMLSLLIKLGSSPFHMWLP-AMCKHISWMTLYLILTWQKLAPLFMLSFINFNYIIIIMCSLT-----------SAILGS 166
Cdd:PRK08375  207 FVLLALALKAAVFPLHTWLPrAYPAAPPVVTALLSGLVTKVAVYALIRIYFTVFGGDFRFALGlgwllavlallSMLVGS 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 167 IQAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMF----LYLLIYSMIIFPLFINMN-YYSNHSTYSLTEQNYnMNKQN 241
Cdd:PRK08375  287 LAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALaaglLHLLHHALMKGALFLAAGaIEVTYGTRRLSELSG-LGRRM 365

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1011058299 242 IF----IIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISL 290
Cdd:PRK08375  366 PLtaaaFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLAL 418
ndhB CHL00049
NADH dehydrogenase subunit 2
 57-303 1.04e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 43.84  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  57 ESSMKYFIIQSLSSSLFIMTMIIMY------------LYSFSTFSMFNNTFMS---SIMMLSLLIKLGSSPFHMWLPAMC 121
Cdd:CHL00049  162 EATMKYLLMGGASSSILVYGFSWLYglsggeielqeiVNGLINTQMYNSPGISialIFITVGIGFKLSLAPFHQWTPDVY 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 122 K----------HISWMTLYLILTWQKLAPLFMLSFINFNYIIIIMCSLtSAILGSIQAINQSSLQMIMVYSSISHLGWM- 190
Cdd:CHL00049  242 EgsptpvvaflSVTSKVAASALATRIFDIPFYFSSNEWHLLLEILAIL-SMILGNLIAITQTSMKRMLAYSSIGQIGYVi 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 191 --LCSCSINN--TLMFLYLLIYsmiifpLFINMNYYSNHSTYSLTEQNYNMN-------KQNIFIIML---ILSLGGMPP 256
Cdd:CHL00049  321 igIIVGDSNDgyASMITYMLFY------IFMNLGTFACIVLFGLRTGTDNIRdyaglytKDPFLALSLalcLLSLGGIPP 394

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1011058299 257 MMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMMMIK 303
Cdd:CHL00049  395 LAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKIIKLLMTG 441
PRK12650 PRK12650
DUF4040 family protein;
112-192 2.81e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 42.72  E-value: 2.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 112 PFHMWLP-AMCK--------HISWMT---LYLILtwqKLAPLFmlSFINFNYIIIIMCSLTSAILGSIQAINQSSLQMIM 179
Cdd:PRK12650  226 PFHFWLPeAMAAitpvsaflHAAAVVkagIYLLL---RFSPVF--HDVAVWNWLLIIVGMITALMGAVFAVQKTDLKKLT 300

                          90
                  ....*....|...
gi 1011058299 180 VYSSISHLGWMLC 192
Cdd:PRK12650  301 AYSTVSQLGWIVA 313
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 161-300 5.33e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 41.88  E-value: 5.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 161 SAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTL----MFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQNYN 236
Cdd:PRK12667  305 SAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLglaaALFHIINHAIAKSLLFLASGVFIHAAGTRDIDELAG 384

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1011058299 237 MNKQNIFI----IMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMM 300
Cdd:PRK12667  385 LGRKMPIAsfafLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSL 452
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 158-267 1.50e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 40.10  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 158 SLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINN----TLMFLYLLIYSMIIFPLFINMNYYSNHSTYSLTEQ 233
Cdd:PRK12662  286 AALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTyyglAAAVAYIVNHSIVKSALFMVSGSISYHFGTTKLED 365

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1011058299 234 NYNMNKQNIFI----IMLILSLGGMPPMMGFLSKLMIL 267
Cdd:PRK12662  366 CLNLWKSMPKItlafVLLSLSLIGMPPTSGFVAKWYIL 403
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 56-266 1.61e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 40.08  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  56 IESSMKYFIIQSLSSSLFIMTMIIMYlYSFSTFSM--------FNNTFMSSIMML----SLLIKLGSSPFHMWLP----- 118
Cdd:PRK08376  171 IEAGIKYMFVGSLASSMVLLGIALLY-GQYGTLNMaylavkmsENPTVVAKIALAlfiaGLAMKSGAVPVHMWLPdaypa 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 119 ------AMCKHISWMTLYLI--LTWQKLAPLFMLSFINFNYIIIIMCSLtsaILGSIQAINQSSLQMIMVYSSISHLGWM 190
Cdd:PRK08376  250 apssisAMLLVIKQAGLYALarVLFSIYGPAINLATVGWVIIILGCLTM---FVGVAMAVVQKDVKRLLAYHSVSQIGYM 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 191 LCSCSI--------------------------NNTLM-FLYLLIYSMIIFPLfinmnyysnhSTYSLTEQN---YNMNKQ 240
Cdd:PRK08376  327 LLGLGVglaalgdpamasygeialaggiyhivNHALYkALLFLTAGAVIYET----------GTRNLNELGglaRTMPKT 396

                         250       260
                  ....*....|....*....|....*.
gi 1011058299 241 NIFIIMLILSLGGMPPMMGFLSKLMI 266
Cdd:PRK08376  397 TIAFLIGAAAIVGLPPFNGFASKWLI 422
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 4-267 2.81e-03

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 39.54  E-value: 2.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299   4 KFFPSNFMFMIMMILGTIMSLSSSHWLMMWmglELNLMGILPLMNIKTKNFEIESSMKYFIIQSLSSSLFIMTMIIMYLY 83
Cdd:TIGR01972 106 KEFYALLLLLEAGVIGVFLALDLFLFYVFW---EAMLIPMYLLIGVWGGPNRIYAAMKFFLYTLAGSLLMLLAILGLYFL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  84 SFSTFSMFN------NTFMSSIMMLSLL----IKLGSSPFHMWLP-AMCKHISWMTLYLILTWQKLAPLFMLSFIN---- 148
Cdd:TIGR01972 183 GGGTFDLLEllnlplPFGVQTWLFLAFFiafaVKVPLFPLHTWLPdAHVEAPTAGSVILAGVLLKMGTYGFLRFNLplfp 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 149 ----FNYIIIIMCSLTSAILGSIQAINQSSLQMIMVYSSISHLGWMLCSCSINNTL----MFLYLLIYSMIIFPLFINMN 220
Cdd:TIGR01972 263 daslYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELgisgAVFQMISHGLITAALFLLVG 342

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1011058299 221 Y-YSNHSTYSLTEQNYNMNKQNI---FIIMLILSLGGMPPMMGFLSKLMIL 267
Cdd:TIGR01972 343 VlYERAHTRDIAKYGGLANKMPVlaaFFMLFAMASLGLPGTSGFVGEFLIL 393
PRK12646 PRK12646
DUF4040 family protein;
95-344 2.92e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 39.35  E-value: 2.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299  95 FMSSIMMLSLLIKLGSSPFHMWLPAMCKHISWMTLYLILTWQKLAPLFML-------SFINFNYIIIIMCSLTSAILGSI 167
Cdd:PRK12646  211 PMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLfrftpllGLSNMYIYIVTFVGLITMLFGSI 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 168 QAINQSSLQMIMVYSSISHLGWMLCSCSINNTLMF-LYLLIYSMIIFPLFINMNYYSNHSTYS----------------- 229
Cdd:PRK12646  291 TALKQWDLKGILAYSTISQLGMIMAMVGIGGGYAQhQQDAIASIYVFVLFAALFHLMNHAIFKcalfmgvgiidheagtr 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 230 ----LTEQNYNMNKQNIFIIMLILSLGGMPPMMGFLSKLMILYMMTKLNMLMLPLILFMSTLISLYFYLNLTMMM----M 301
Cdd:PRK12646  371 diriLSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMIIIVFIGVIASIFTFTyalyM 450

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1011058299 302 IKSFFLLNINKMKMTTKSI-----MCLNMMSTIIFIPMMMYAMNILNK 344
Cdd:PRK12646  451 VKEVFWGKYDSKVFTKKNIhepwlFSLPSLILMVLVPVIFFVPNIFGK 498
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 112-291 4.68e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 38.59  E-value: 4.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 112 PFHMWLP-AMCK--------HISWMT---LYLILtwqKLAPLFMLSFINFNYIIIImcSLTSAILGSIQAINQSSLQMIM 179
Cdd:COG1009   229 PLHFWLPdAMEGptpvsallHAATMVkagVYLLA---RLSPLFALSPVWLTVVAII--GAITALFAALIALAQTDIKRVL 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011058299 180 VYSSISHLGWMLCSCSINNTLMFLYLLIysmiifplfinmnyysNHSTY---------SLTeqnYNMNKQNI-------- 242
Cdd:COG1009   304 AYSTVSQLGYMFLALGVGAYVAALFHLL----------------THAFFkallflgagSVI---HATGTRDIrkmgglrk 364

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1011058299 243 -----FIIMLI--LSLGGMPPMMGFLSKLMIL---YMMTKLNMLMLPLILFMSTLISLY 291
Cdd:COG1009   365 kmpitAITFLIgaLSLAGIPPFAGFFSKEAILeaaLEAGGLGPLLLAVALLGAFLTAFY 423
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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