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Conserved domains on  [gi|257136421|ref|YP_003169695|]
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holin [Staphylococcus phage P954]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Hol_Tox super family cl25207
Putative Holin-like Toxin (Hol-Tox); Hol_Tox is a family of small proteins (34-48aas) with a ...
 1-43 9.84e-08

Putative Holin-like Toxin (Hol-Tox); Hol_Tox is a family of small proteins (34-48aas) with a single TM region. Members can exhibit antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria.


The actual alignment was detected with superfamily member NF041589:

Pssm-ID: 474544  Cd Length: 46  Bit Score: 42.13  E-value: 9.84e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 257136421  1 MVALLKSLERRRLMI---TISTMLQFGLFLIALIGLVIKLIELSNK 43
Cdd:NF041589  1 MSVLPKSLERRRLLIayeTIQTILGFGIFTIALIGLVVKLLKNSKK 46
 
Name Accession Description Interval E-value
PepG1 NF041589
type I toxin-antitoxin system toxin PepG1;
1-43 9.84e-08

type I toxin-antitoxin system toxin PepG1;


Pssm-ID: 469474  Cd Length: 46  Bit Score: 42.13  E-value: 9.84e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 257136421  1 MVALLKSLERRRLMI---TISTMLQFGLFLIALIGLVIKLIELSNK 43
Cdd:NF041589  1 MSVLPKSLERRRLLIayeTIQTILGFGIFTIALIGLVVKLLKNSKK 46
Hol_Tox pfam16935
Putative Holin-like Toxin (Hol-Tox); Hol_Tox is a family of small proteins (34-48aas) with a ...
 16-44 1.04e-03

Putative Holin-like Toxin (Hol-Tox); Hol_Tox is a family of small proteins (34-48aas) with a single TM region. Members can exhibit antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria.


Pssm-ID: 435666  Cd Length: 34  Bit Score: 31.65  E-value: 1.04e-03
                         10        20
                 ....*....|....*....|....*....
gi 257136421  16 TISTMLQFGLFLIALIGLVIKLIELSNKK 44
Cdd:pfam16935  6 ALSLMIAFGSFIIALLTLVVIIIKLNKKK 34
 
Name Accession Description Interval E-value
PepG1 NF041589
type I toxin-antitoxin system toxin PepG1;
1-43 9.84e-08

type I toxin-antitoxin system toxin PepG1;


Pssm-ID: 469474  Cd Length: 46  Bit Score: 42.13  E-value: 9.84e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 257136421  1 MVALLKSLERRRLMI---TISTMLQFGLFLIALIGLVIKLIELSNK 43
Cdd:NF041589  1 MSVLPKSLERRRLLIayeTIQTILGFGIFTIALIGLVVKLLKNSKK 46
Hol_Tox pfam16935
Putative Holin-like Toxin (Hol-Tox); Hol_Tox is a family of small proteins (34-48aas) with a ...
 16-44 1.04e-03

Putative Holin-like Toxin (Hol-Tox); Hol_Tox is a family of small proteins (34-48aas) with a single TM region. Members can exhibit antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria.


Pssm-ID: 435666  Cd Length: 34  Bit Score: 31.65  E-value: 1.04e-03
                         10        20
                 ....*....|....*....|....*....
gi 257136421  16 TISTMLQFGLFLIALIGLVIKLIELSNKK 44
Cdd:pfam16935  6 ALSLMIAFGSFIIALLTLVVIIIKLNKKK 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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