NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2133659959|ref|XP_044962160|]
View 

membrane-anchored ubiquitin-fold protein 3-like [Hordeum vulgare subsp. vulgare]

Protein Classification

Rad60-SLD_2 domain-containing protein( domain architecture ID 10620708)

Rad60-SLD_2 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Rad60-SLD_2 pfam13881
Ubiquitin-2 like Rad60 SUMO-like;
6-116 1.37e-60

Ubiquitin-2 like Rad60 SUMO-like;


:

Pssm-ID: 372780  Cd Length: 111  Bit Score: 180.97  E-value: 1.37e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2133659959   6 EPIEVKFRLFDGTDIGPNKYDPATTVTALKEFVLARWPQDKDIVPKTLNDVKLINAGRILENNKTLAESRVPVGEVPGGV 85
Cdd:pfam13881   1 DQIELKFRLVDGSDIGPFVFSPATTVADLKEKVIAQWPKDKENGPKTVNDVKLINAGKILENNKTLGECRLPVGETPGGV 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2133659959  86 ITMHVVVRPPQSDKSDKHLSNSPKQNRCGCT 116
Cdd:pfam13881  81 TTMHVVVRPNLPEPNSEKKANKPKQNGCGCC 111
 
Name Accession Description Interval E-value
Rad60-SLD_2 pfam13881
Ubiquitin-2 like Rad60 SUMO-like;
6-116 1.37e-60

Ubiquitin-2 like Rad60 SUMO-like;


Pssm-ID: 372780  Cd Length: 111  Bit Score: 180.97  E-value: 1.37e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2133659959   6 EPIEVKFRLFDGTDIGPNKYDPATTVTALKEFVLARWPQDKDIVPKTLNDVKLINAGRILENNKTLAESRVPVGEVPGGV 85
Cdd:pfam13881   1 DQIELKFRLVDGSDIGPFVFSPATTVADLKEKVIAQWPKDKENGPKTVNDVKLINAGKILENNKTLGECRLPVGETPGGV 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2133659959  86 ITMHVVVRPPQSDKSDKHLSNSPKQNRCGCT 116
Cdd:pfam13881  81 TTMHVVVRPNLPEPNSEKKANKPKQNGCGCC 111
Ubl_MUBs_plant cd01814
ubiquitin-like (Ubl) domain found in plant membrane-anchored ubiquitin-fold proteins (MUBs); ...
 8-95 6.08e-47

ubiquitin-like (Ubl) domain found in plant membrane-anchored ubiquitin-fold proteins (MUBs); The plant MUBs belong to a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation. They may serve as docking site to facilitate the association of specific E2s to the plasma membrane. MUBs contain a ubiquitin-like (Ubl) domain with a beta-grasp Ubl fold.


Pssm-ID: 340512  Cd Length: 89  Bit Score: 145.98  E-value: 6.08e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2133659959   8 IEVKFRLFDGTDIGPNKYDPATTVTALKEFVLARWPQDKDIVPKTLNDVKLINAGRILENNKTLAESRVPVGEVPGGVIT 87
Cdd:cd01814     2 IEIKFRLTDGSDIGPFRYSSATTVATLKEKVIAEWPKDKENGPKSINDVKLIYAGKVLENGKTLADSRTPGKVPPGGVIT 81


                  ....*...
gi 2133659959  88 MHVVVRPP 95
Cdd:cd01814    82 MHVVVRPP 89
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 26-76 2.09e-04

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 39.11  E-value: 2.09e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2133659959  26 DPATTVTALKEFVLARwpQDKDIVPktLNDVKLINAGRILENNKTLAESRV 76
Cdd:TIGR00601  18 EPDETVKELKEKIEAE--QGKDAYP--VAQQKLIYSGKILSDDKTVKEYKI 64
 
Name Accession Description Interval E-value
Rad60-SLD_2 pfam13881
Ubiquitin-2 like Rad60 SUMO-like;
6-116 1.37e-60

Ubiquitin-2 like Rad60 SUMO-like;


Pssm-ID: 372780  Cd Length: 111  Bit Score: 180.97  E-value: 1.37e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2133659959   6 EPIEVKFRLFDGTDIGPNKYDPATTVTALKEFVLARWPQDKDIVPKTLNDVKLINAGRILENNKTLAESRVPVGEVPGGV 85
Cdd:pfam13881   1 DQIELKFRLVDGSDIGPFVFSPATTVADLKEKVIAQWPKDKENGPKTVNDVKLINAGKILENNKTLGECRLPVGETPGGV 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2133659959  86 ITMHVVVRPPQSDKSDKHLSNSPKQNRCGCT 116
Cdd:pfam13881  81 TTMHVVVRPNLPEPNSEKKANKPKQNGCGCC 111
Ubl_MUBs_plant cd01814
ubiquitin-like (Ubl) domain found in plant membrane-anchored ubiquitin-fold proteins (MUBs); ...
 8-95 6.08e-47

ubiquitin-like (Ubl) domain found in plant membrane-anchored ubiquitin-fold proteins (MUBs); The plant MUBs belong to a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation. They may serve as docking site to facilitate the association of specific E2s to the plasma membrane. MUBs contain a ubiquitin-like (Ubl) domain with a beta-grasp Ubl fold.


Pssm-ID: 340512  Cd Length: 89  Bit Score: 145.98  E-value: 6.08e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2133659959   8 IEVKFRLFDGTDIGPNKYDPATTVTALKEFVLARWPQDKDIVPKTLNDVKLINAGRILENNKTLAESRVPVGEVPGGVIT 87
Cdd:cd01814     2 IEIKFRLTDGSDIGPFRYSSATTVATLKEKVIAEWPKDKENGPKSINDVKLIYAGKVLENGKTLADSRTPGKVPPGGVIT 81


                  ....*...
gi 2133659959  88 MHVVVRPP 95
Cdd:cd01814    82 MHVVVRPP 89
Ubl_UBL3 cd17048
ubiquitin-like (Ubl) domain found in ubiquitin-like protein 3 (UBL3) and similar proteins; ...
 27-93 9.80e-06

ubiquitin-like (Ubl) domain found in ubiquitin-like protein 3 (UBL3) and similar proteins; UBL3, also termed membrane-anchored ubiquitin-fold protein (MUB), or protein HCG-1, belongs to a newly described MUB protein family with structural homology with ubiquitin. MUB proteins have a beta-grasp ubiquitin-like (Ubl) domain with longer N- and C-termini and extended loops. The Ubl domain contains a C-terminal CAAX-box, a canonical motif for protein prenylation, which is modified through protein lipidation with a hydrophobic membrane anchor. The lipidation and membrane localization inhibit attachment of MUBs to target proteins.


Pssm-ID: 340568  Cd Length: 82  Bit Score: 40.82  E-value: 9.80e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2133659959  27 PATTVTALKEFVLARWPQD--KDIVPKTlNDVKLINAGRILENNKTLAESRVPVGEvpggVITMHVVVR 93
Cdd:cd17048    19 PNDSAADIAQHVFDNWPEDweEEQVSSA-NILRLIYQGRFLHGNVTLGALQLPLGK----TTVMHLVAR 82
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 26-76 2.09e-04

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 39.11  E-value: 2.09e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2133659959  26 DPATTVTALKEFVLARwpQDKDIVPktLNDVKLINAGRILENNKTLAESRV 76
Cdd:TIGR00601  18 EPDETVKELKEKIEAE--QGKDAYP--VAQQKLIYSGKILSDDKTVKEYKI 64
ubiquitin pfam00240
Ubiquitin family; This family contains a number of ubiquitin-like proteins: SUMO (smt3 homolog) ...
 10-95 7.21e-03

Ubiquitin family; This family contains a number of ubiquitin-like proteins: SUMO (smt3 homolog), Nedd8, Elongin B, Rub1, and Parkin. A number of them are thought to carry a distinctive five-residue motif termed the proteasome-interacting motif (PIM), which may have a biologically significant role in protein delivery to proteasomes and recruitment of proteasomes to transcription sites.


Pssm-ID: 459726 [Multi-domain]  Cd Length: 72  Bit Score: 32.91  E-value: 7.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2133659959  10 VKFRLFDGTDIgPNKYDPATTVTALKEFVLARwpqdKDIVPktlNDVKLINAGRILENNKTLAEsrvpVGEVPGGVItmH 89
Cdd:pfam00240   1 ITVKTLDGKKI-TLEVDPTDTVLELKEKIAEK----EGVPP---EQQRLIYSGKVLEDDQTLGE----YGIEDGSTI--H 66


                  ....*.
gi 2133659959  90 VVVRPP 95
Cdd:pfam00240  67 LVLRQR 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH