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Conserved domains on  [gi|2130968055|ref|XP_044913518|]
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kinesin light chain 4 [Felis catus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11420945)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
205-411 1.40e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 108.56  E-value: 1.40e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestl 284
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 285 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRekvlgtdhPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIy 364
Cdd:COG0457    72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2130968055 365 egqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQEF 411
Cdd:COG0457   140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALL 179
TPR_12 pfam13424
Tetratricopeptide repeat;
375-493 5.66e-05

Tetratricopeptide repeat;


:

Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 5.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 375 VARTKNNLASCYLKQGKYAEAETLYKEILTRAHlqefgsvdddhkpiwmhaeereemsksrhREGGTPYTEYGgwykack 454
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIAR-----------------------------RLLGPDHPLTA------- 45
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2130968055 455 vssptvnTTLRNLGALYRRQGKLEAAETLEECALRSQKQ 493
Cdd:pfam13424  46 -------TTLLNLGRLYLELGRYEEALELLERALALAEK 77
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
33-148 2.48e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 2.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055   33 LEALHSEHQAVLQSLSHTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQ-VMLALASHLSTVESEKQKLRAQVRR 111
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkELYALANEISRLEQQKQILRERLAN 313
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2130968055  112 LCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLE 148
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
205-411 1.40e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 108.56  E-value: 1.40e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestl 284
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 285 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRekvlgtdhPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIy 364
Cdd:COG0457    72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2130968055 365 egqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQEF 411
Cdd:COG0457   140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALL 179
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
220-416 2.53e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 95.37  E-value: 2.53e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 220 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI--RESTLGRDHPAVAATLNN 297
Cdd:NF040586  404 LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGG 483
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 298 LAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIYEGQLGPDNPNVAR 377
Cdd:NF040586  484 LGADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLL 563
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2130968055 378 TKNNLASCYLKQGKYAEAETLYKEILTRaHLQEFGSVDD 416
Cdd:NF040586  564 SANNLARDLRELGRYAEALDLLEEALER-YREVLGGPDH 601
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
192-489 4.71e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 94.60  E-value: 4.71e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 192 SRGQGAQHsgyeiPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAH 271
Cdd:NF040586  467 VLGLGEDH-----PHTLMTAGGLGADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALE 541
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 272 LLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVL-GTDHPDVAKQLNNLALLCQNQGKY 350
Cdd:NF040586  542 LDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVLgGPDHPDTLRAAKSLAVALRRAGRL 621
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 351 EAVERYYRRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRaHLQEFGsvdDDHkpiwmhaeeree 430
Cdd:NF040586  622 EEALELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDR-YRRVLG---EDH------------ 685
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2130968055 431 msksrhreggtPYTeyggwyKACKVssptvnttlrNLGALYRRQGKLEAAETLEECALR 489
Cdd:NF040586  686 -----------PFT------LACRN----------NLAVLLRALGDPEEARELAEAALE 717
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
193-405 6.91e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 91.13  E-value: 6.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 193 RGQGAQHSGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD-VATMLNiLALVYRDQNKYKEAAH 271
Cdd:NF040586  590 ERYREVLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARE 668
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 272 LLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHP---DVAKQL-NNLALLCQNQ 347
Cdd:NF040586  669 LAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPytlAAAVNLaNDLAALGDLD 748
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2130968055 348 GKYEAVERYYRRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTR 405
Cdd:NF040586  749 AALGEEALERLRRLLGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLAR 806
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
191-418 1.42e-18

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 89.98  E-value: 1.42e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 191 LSRGQGAQHsgyeiPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERT-SGRGHPDVATMLNILALVYRDQNKYKEA 269
Cdd:NF040586  550 RRRVLGPDH-----PRTLLSANNLARDLRELGRYAEALDLLEEALERYREVlGGPDHPDTLRAAKSLAVALRRAGRLEEA 624
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 270 AHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGK 349
Cdd:NF040586  625 LELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGD 704
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130968055 350 YEAVERYYRRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQEFGSVDDDH 418
Cdd:NF040586  705 PEEARELAEAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAALGEEALERLRRLLGEDLRAGPDH 773
TPR_12 pfam13424
Tetratricopeptide repeat;
291-365 4.13e-17

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 76.27  E-value: 4.13e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2130968055 291 VAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIYE 365
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAE 76
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
193-375 6.63e-17

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 84.59  E-value: 6.63e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 193 RGQGAQHsgyeiPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHL 272
Cdd:NF040586  637 RRFGPDH-----PDTLAAALSLANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEAREL 711
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 273 LNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLC----QRALEIREKVLGTDHPDVAKQLNNLALLCQNQG 348
Cdd:NF040586  712 AEAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAALGEEalerLRRLLGEDLRAGPDHPDTLACAANLALDLRATG 791
                         170       180
                  ....*....|....*....|....*..
gi 2130968055 349 KYEAVERYYRRALAIYEGQLGPDNPNV 375
Cdd:NF040586  792 RTEEAEELRADTLARLRRVLGPDHPDT 818
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
206-409 3.82e-09

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 57.35  E-value: 3.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 206 ARLRTlhNLVIQYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestlg 285
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLEVAKENLDKALEH--------DPDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 286 rdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEirekvlGTDHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIye 365
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2130968055 366 gqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQ 409
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLERYQQTYNQT 202
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
301-405 1.35e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 48.38  E-value: 1.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 301 LYgKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVER------------------------- 355
Cdd:NF040586  402 LY-LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEAREldedtlerqrrvlglgedhphtlmt 480
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130968055 356 ------------YYRRALAI----YEGQ---LGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTR 405
Cdd:NF040586  481 agglgadlralgRFREALELdeetLERHrrvFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRR 549
TPR_12 pfam13424
Tetratricopeptide repeat;
375-493 5.66e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 5.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 375 VARTKNNLASCYLKQGKYAEAETLYKEILTRAHlqefgsvdddhkpiwmhaeereemsksrhREGGTPYTEYGgwykack 454
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIAR-----------------------------RLLGPDHPLTA------- 45
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2130968055 455 vssptvnTTLRNLGALYRRQGKLEAAETLEECALRSQKQ 493
Cdd:pfam13424  46 -------TTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
292-324 1.70e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 1.70e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2130968055  292 AATLNNLAVLYGKRGKYKEAEPLCQRALEIREK 324
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
182-293 3.81e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 43.75  E-value: 3.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 182 EEEEDPSNGLSRGQGAQHsgyeiPARLRTLHNLVIQYAAQGRYEVAvpLCKQALEDLERTSGRG------HPDVATMLNI 255
Cdd:NF040586  710 ELAEAALEGLRERLGPDH-----PYTLAAAVNLANDLAALGDLDAA--LGEEALERLRRLLGEDlragpdHPDTLACAAN 782
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2130968055 256 LALVYRDQNKYKEAAHLLNDALSIRESTLGRDHPAVAA 293
Cdd:NF040586  783 LALDLRATGRTEEAEELRADTLARLRRVLGPDHPDTVA 820
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
206-389 1.19e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 41.99  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055  206 ARLRTLHNLviqyaAQGRYEVAVPLCKQALedlertsgRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLG 285
Cdd:PRK11447   272 ARAQGLAAV-----DSGQGGKAIPELQQAV--------RANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPHSSN 338
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055  286 RDHPAVAATLNN--LAVLYG----KRGKYKEAEPLCQRALEIREK----VLGTDhpDVAkqlnnLAllcqnQGKYEAVER 355
Cdd:PRK11447   339 RDKWESLLKVNRywLLIQQGdaalKANNLAQAERLYQQARQVDNTdsyaVLGLG--DVA-----MA-----RKDYAAAER 406
                          170       180       190
                   ....*....|....*....|....*....|....
gi 2130968055  356 YYRRALaiyegQLGPDNPNVARtknNLASCYLKQ 389
Cdd:PRK11447   407 YYQQAL-----RMDPGNTNAVR---GLANLYRQQ 432
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
261-406 1.44e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 41.18  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 261 RDQNKYKEAAHLLNDA--LSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPdvAKQ-- 336
Cdd:cd24145   114 SELGKWELRERLLKKAveILLKLGELWMSPSEVGAFLEELATAYDLYGRFCLALPLYMQALSLKGQILLSQAN--CHSlv 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 337 -LNNLAL-LCQNQGK---------------------YEAVERYYRRALAIYEgqlgpDNPNVARTKN----------NLA 383
Cdd:cd24145   192 lMNNEAAeLALHALRkplsstlieasrlpqksrdqlLEAALKWAQKALDVAK-----SIKPKDRDPEcdqacalalyNLG 266
                         170       180
                  ....*....|....*....|...
gi 2130968055 384 SCYLKQGKYAEAETLYKEILTRA 406
Cdd:cd24145   267 VIAEMLGNLDEARKLYKEAISLA 289
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
33-148 2.48e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 2.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055   33 LEALHSEHQAVLQSLSHTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQ-VMLALASHLSTVESEKQKLRAQVRR 111
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkELYALANEISRLEQQKQILRERLAN 313
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2130968055  112 LCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLE 148
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
205-411 1.40e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 108.56  E-value: 1.40e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestl 284
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 285 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRekvlgtdhPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIy 364
Cdd:COG0457    72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2130968055 365 egqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQEF 411
Cdd:COG0457   140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALL 179
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
220-416 2.53e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 95.37  E-value: 2.53e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 220 AQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI--RESTLGRDHPAVAATLNN 297
Cdd:NF040586  404 LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGG 483
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 298 LAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIYEGQLGPDNPNVAR 377
Cdd:NF040586  484 LGADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLL 563
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2130968055 378 TKNNLASCYLKQGKYAEAETLYKEILTRaHLQEFGSVDD 416
Cdd:NF040586  564 SANNLARDLRELGRYAEALDLLEEALER-YREVLGGPDH 601
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
192-489 4.71e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 94.60  E-value: 4.71e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 192 SRGQGAQHsgyeiPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAH 271
Cdd:NF040586  467 VLGLGEDH-----PHTLMTAGGLGADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALE 541
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 272 LLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVL-GTDHPDVAKQLNNLALLCQNQGKY 350
Cdd:NF040586  542 LDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVLgGPDHPDTLRAAKSLAVALRRAGRL 621
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 351 EAVERYYRRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRaHLQEFGsvdDDHkpiwmhaeeree 430
Cdd:NF040586  622 EEALELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDR-YRRVLG---EDH------------ 685
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2130968055 431 msksrhreggtPYTeyggwyKACKVssptvnttlrNLGALYRRQGKLEAAETLEECALR 489
Cdd:NF040586  686 -----------PFT------LACRN----------NLAVLLRALGDPEEARELAEAALE 717
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
191-406 5.96e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 93.90  E-value: 5.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 191 LSRGQGAQHSGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRghPDVATMLNILALVYRDQNKYKEAA 270
Cdd:COG3914    21 AAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAAL--LLLAALLELAALLLQALGRYEEAL 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 271 HLLNDALSIrestlgrdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAKQLNNLALLCQNQGKY 350
Cdd:COG3914    99 ALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDFAEAYLNLGEALRRLGRL 162
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2130968055 351 EAVERYYRRALAIyegqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:COG3914   163 EEAIAALRRALEL--------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
193-405 6.91e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 91.13  E-value: 6.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 193 RGQGAQHSGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD-VATMLNiLALVYRDQNKYKEAAH 271
Cdd:NF040586  590 ERYREVLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARE 668
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 272 LLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHP---DVAKQL-NNLALLCQNQ 347
Cdd:NF040586  669 LAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPytlAAAVNLaNDLAALGDLD 748
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2130968055 348 GKYEAVERYYRRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTR 405
Cdd:NF040586  749 AALGEEALERLRRLLGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLAR 806
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
191-418 1.42e-18

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 89.98  E-value: 1.42e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 191 LSRGQGAQHsgyeiPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERT-SGRGHPDVATMLNILALVYRDQNKYKEA 269
Cdd:NF040586  550 RRRVLGPDH-----PRTLLSANNLARDLRELGRYAEALDLLEEALERYREVlGGPDHPDTLRAAKSLAVALRRAGRLEEA 624
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 270 AHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGK 349
Cdd:NF040586  625 LELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGD 704
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130968055 350 YEAVERYYRRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQEFGSVDDDH 418
Cdd:NF040586  705 PEEARELAEAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAALGEEALERLRRLLGEDLRAGPDH 773
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
205-409 9.22e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 83.13  E-value: 9.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRestl 284
Cdd:COG0457    39 PDDAEALYNLGLAYLRLGRYEEALADYEQALEL--------DPDDAEALNNLGLALQALGRYEEALEDYDKALELD---- 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 285 grdhPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRekvlgtdhPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIY 364
Cdd:COG0457   107 ----PDDAEALYNLGLALLELGRYDEAIEAYERALELD--------PDDADALYNLGIALEKLGRYEEALELLEKLEAAA 174
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2130968055 365 EGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQ 409
Cdd:COG0457   175 LAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAAL 219
TPR_12 pfam13424
Tetratricopeptide repeat;
291-365 4.13e-17

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 76.27  E-value: 4.13e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2130968055 291 VAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIYE 365
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAE 76
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
193-375 6.63e-17

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 84.59  E-value: 6.63e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 193 RGQGAQHsgyeiPARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHL 272
Cdd:NF040586  637 RRFGPDH-----PDTLAAALSLANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEAREL 711
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 273 LNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLC----QRALEIREKVLGTDHPDVAKQLNNLALLCQNQG 348
Cdd:NF040586  712 AEAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAALGEEalerLRRLLGEDLRAGPDHPDTLACAANLALDLRATG 791
                         170       180
                  ....*....|....*....|....*..
gi 2130968055 349 KYEAVERYYRRALAIYEGQLGPDNPNV 375
Cdd:NF040586  792 RTEEAEELRADTLARLRRVLGPDHPDT 818
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
218-491 3.01e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 79.39  E-value: 3.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 218 YAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRestlgrdhPAVAATLNN 297
Cdd:COG2956    52 YRRRGEYDRAIRIHQKLLER--------DPDRAEALLELAQDYLKAGLLDRAEELLEKLLELD--------PDDAEALRL 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 298 LAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIyegqlgpdNPNVAR 377
Cdd:COG2956   116 LAEIYEQEGDWEKAIEVLERLLKL--------GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCAR 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 378 TKNNLASCYLKQGKYAEAETLYKEILTRahlqefgsvDDDHKPIwmhaeeREEMSKSRHREGGtpYTEYGGWYKACKVSS 457
Cdd:COG2956   180 ALLLLAELYLEQGDYEEAIAALERALEQ---------DPDYLPA------LPRLAELYEKLGD--PEEALELLRKALELD 242
                         250       260       270
                  ....*....|....*....|....*....|....
gi 2130968055 458 PTvNTTLRNLGALYRRQGKLEAAETLEECALRSQ 491
Cdd:COG2956   243 PS-DDLLLALADLLERKEGLEAALALLERQLRRH 275
TPR_12 pfam13424
Tetratricopeptide repeat;
248-324 2.84e-15

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 70.88  E-value: 2.84e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2130968055 248 DVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREK 324
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
217-406 6.53e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 75.03  E-value: 6.53e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 217 QYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRE-STLGRDHPAVAATL 295
Cdd:COG3914     2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEaAAAAAALLLLAALL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 296 NNLAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIyegqlgpdNPNV 375
Cdd:COG3914    82 ELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDF 145
                         170       180       190
                  ....*....|....*....|....*....|.
gi 2130968055 376 ARTKNNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:COG3914   146 AEAYLNLGEALRRLGRLEEAIAALRRALELD 176
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
217-493 7.64e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.07  E-value: 7.64e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 217 QYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestlgrdHPAVAATLN 296
Cdd:COG2956    17 NYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER--------DPDRAEALL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 297 NLAVLYGKRGKYKEAEPLCQRALEIRekvlgtdhPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIyegqlgpdNPNVA 376
Cdd:COG2956    81 ELAQDYLKAGLLDRAEELLEKLLELD--------PDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL--------GPENA 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 377 RTKNNLASCYLKQGKYAEAETLYKEILtrahlqefgSVDDDHKPIWMHAEEREEMSKSrhreggtpYTEYGGWYKACKVS 456
Cdd:COG2956   145 HAYCELAELYLEQGDYDEAIEALEKAL---------KLDPDCARALLLLAELYLEQGD--------YEEAIAALERALEQ 207
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2130968055 457 SPTVNTTLRNLGALYRRQGKLEAAETLEECALRSQKQ 493
Cdd:COG2956   208 DPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244
TPR_12 pfam13424
Tetratricopeptide repeat;
332-406 1.92e-13

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 65.87  E-value: 1.92e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2130968055 332 DVAKQLNNLALLCQNQGKYEAVERYYRRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
TPR_10 pfam13374
Tetratricopeptide repeat;
291-332 5.07e-13

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 63.29  E-value: 5.07e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2130968055 291 VAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPD 332
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
256-406 5.66e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.37  E-value: 5.66e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 256 LALVYRDQNKYKEAAHLLNDALsirestlgRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAK 335
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKAL--------ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL--------DPDEPE 73
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2130968055 336 QLNNLALLCQNQGKYEAVERYYRRALAIYegqlgPDNPNVARtknNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:COG4783    74 ARLNLGLALLKAGDYDEALALLEKALKLD-----PEHPEAYL---RLARAYRALGRPDEAIAALEKALELD 136
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
206-364 2.11e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.83  E-value: 2.11e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 206 ARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestlg 285
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL------ 67
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130968055 286 rdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEirekvLGTDHPDVakqLNNLALLCQNQGKYEAVERYYRRALAIY 364
Cdd:COG4783    68 --DPDEPEARLNLGLALLKAGDYDEALALLEKALK-----LDPEHPEA---YLRLARAYRALGRPDEAIAALEKALELD 136
TPR_12 pfam13424
Tetratricopeptide repeat;
207-282 3.91e-12

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 62.02  E-value: 3.91e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2130968055 207 RLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRES 282
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
255-406 9.50e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.91  E-value: 9.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 255 ILALVYRDQNKYKEAAHLLNDALSIrestlgrdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVA 334
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER--------DPDRA 76
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2130968055 335 KQLNNLALLCQNQGKYEAVERYYRRALaiyegQLGPDNPNVARtknNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLL-----ELDPDDAEALR---LLAEIYEQEGDWEKAIEVLERLLKLG 140
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
301-403 1.31e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 60.95  E-value: 1.31e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 301 LYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAKQLNNLALLCQNQGKYEAVERYyRRALAIyegqlgpdNPNVARTKN 380
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63
                          90       100
                  ....*....|....*....|...
gi 2130968055 381 NLASCYLKQGKYAEAETLYKEIL 403
Cdd:COG3063    64 NLAELLLELGDYDEALAYLERAL 86
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
250-409 1.37e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 63.06  E-value: 1.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 250 ATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIrekvlgtd 329
Cdd:COG5010    12 LYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL-------- 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 330 HPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIyegqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQ 409
Cdd:COG5010    84 DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPLK 155
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
205-368 7.32e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 7.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEdlertsgrGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRestl 284
Cdd:COG0457    73 PDDAEALNNLGLALQALGRYEEALEDYDKALE--------LDPDDAEALYNLGLALLELGRYDEAIEAYERALELD---- 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 285 grdhPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIY 364
Cdd:COG0457   141 ----PDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTL 216

                  ....
gi 2130968055 365 EGQL 368
Cdd:COG0457   217 AALA 220
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
259-363 1.80e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.87  E-value: 1.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 259 VYRDQNKYKEAAHLLNDALSIrestlgrdHPAVAATLNNLAVLYGKRGKYKEAEPLcQRALEIrekvlgtdHPDVAKQLN 338
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63
                          90       100
                  ....*....|....*....|....*
gi 2130968055 339 NLALLCQNQGKYEAVERYYRRALAI 363
Cdd:COG3063    64 NLAELLLELGDYDEALAYLERALEL 88
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
290-406 3.95e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.28  E-value: 3.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 290 AVAATLNNLAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIYegqlg 369
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD----- 68
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2130968055 370 PDNPNVArtkNNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:COG4783    69 PDEPEAR---LNLGLALLKAGDYDEALALLEKALKLD 102
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
205-363 1.07e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 57.66  E-value: 1.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestl 284
Cdd:COG5010     9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL----- 83
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130968055 285 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAI 363
Cdd:COG5010    84 ---DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
213-400 1.99e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.00  E-value: 1.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 213 NLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRestlgrdhPAVA 292
Cdd:COG4785    36 ALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLA 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 293 ATLNNLAVLYGKRGKYKEAEPLCQRALEIRekvlgtdhPDVAKQLNNLALLCQNQGKYEAVERYYRRALA---------- 362
Cdd:COG4785   108 EAYNNRGLAYLLLGDYDAALEDFDRALELD--------PDYAYAYLNRGIALYYLGRYELAIADLEKALEldpndperal 179
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2130968055 363 ---IYEGQLGPDnPNVARTKNNLASCYLKQGKYAEAETLYK 400
Cdd:COG4785   180 wlyLAERKLDPE-KALALLLEDWATAYLLQGDTEEARELFK 219
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
256-429 2.66e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 57.62  E-value: 2.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 256 LALVYRDQNKYKEAAHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRekvlgtdhPDVAK 335
Cdd:COG4785    37 LAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLAE 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 336 QLNNLALLCQNQGKYEAVERYYRRALAIyegqlgpdNPNVARTKNNLASCYLKQGKYAEAEtlykeiltrAHLQEFGSVD 415
Cdd:COG4785   109 AYNNRGLAYLLLGDYDAALEDFDRALEL--------DPDYAYAYLNRGIALYYLGRYELAI---------ADLEKALELD 171
                         170
                  ....*....|....*.
gi 2130968055 416 --DDHKPIWMHAEERE 429
Cdd:COG4785   172 pnDPERALWLYLAERK 187
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
286-406 2.88e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.40  E-value: 2.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 286 RDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRekvlgtdhPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIye 365
Cdd:COG4235    11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL-- 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2130968055 366 gqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:COG4235    81 ------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
206-409 3.82e-09

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 57.35  E-value: 3.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 206 ARLRTlhNLVIQYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestlg 285
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLEVAKENLDKALEH--------DPDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 286 rdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEirekvlGTDHPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIye 365
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2130968055 366 gqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHLQ 409
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLERYQQTYNQT 202
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
205-364 5.26e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.43  E-value: 5.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestl 284
Cdd:COG2956   141 PENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCARALLLLAELYLEQGDYEEAIAALERALEQ----- 207
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 285 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAkQLNNLALLCQNQGKYEAVERYYRRALAIY 364
Cdd:COG2956   208 ---DPDYLPALPRLAELYEKLGDPEEALELLRKALEL--------DPSDD-LLLALADLLERKEGLEAALALLERQLRRH 275
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
218-326 6.27e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 53.64  E-value: 6.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 218 YAAQGRYEVAVPLCKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLlNDALSIrestlgrdHPAVAATLNN 297
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALLN 64
                          90       100
                  ....*....|....*....|....*....
gi 2130968055 298 LAVLYGKRGKYKEAEPLCQRALEIREKVL 326
Cdd:COG3063    65 LAELLLELGDYDEALAYLERALELDPSAL 93
TPR_10 pfam13374
Tetratricopeptide repeat;
249-289 1.43e-08

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 50.96  E-value: 1.43e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2130968055 249 VATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGRDHP 289
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHP 41
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
244-404 1.79e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.79  E-value: 1.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 244 RGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestlgrdHPAVAATLNNLAVLYGKRgKYKEAEPLCQRALEIRe 323
Cdd:TIGR02917 764 KTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKK--------APDNAVVLNNLAWLYLEL-KDPRALEYAERALKLA- 833
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 324 kvlgtdhPDVAKQLNNLALLCQNQGKYEAVERYYRRALAIyegqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 403
Cdd:TIGR02917 834 -------PNIPAILDTLGWLLVEKGEADRALPLLRKAVNI--------APEAAAIRYHLALALLATGRKAEARKELDKLL 898

                  .
gi 2130968055 404 T 404
Cdd:TIGR02917 899 N 899
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
304-405 2.65e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 52.30  E-value: 2.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 304 KRGKYKEAEPLCQRALEirekvlgtDHPD---VAKQLNNLALLCQNQGKYEAVERYYRRALAIYegqlgPDNPNVARTKN 380
Cdd:COG1729     5 KAGDYDEAIAAFKAFLK--------RYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY-----PDSPKAPDALL 71
                          90       100
                  ....*....|....*....|....*
gi 2130968055 381 NLASCYLKQGKYAEAETLYKEILTR 405
Cdd:COG1729    72 KLGLSYLELGDYDKARATLEELIKK 96
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
218-406 2.84e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 2.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 218 YAAQGRYEVAVPLCKQALEdLERTSGrghpdvATMLniLALVYRDQNKYKEAAHLLNDALsirestlgRDHPAVAATLNN 297
Cdd:TIGR02917 713 YLRQKDYPAAIQAYRKALK-RAPSSQ------NAIK--LHRALLASGNTAEAVKTLEAWL--------KTHPNDAVLRTA 775
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 298 LAVLYGKRGKYKEAEPLCQRALEIrekvlgtdHPDVAKQLNNLALLCQNQGKYEAVErYYRRALaiyegQLGPDNPNVAR 377
Cdd:TIGR02917 776 LAELYLAQKDYDKAIKHYQTVVKK--------APDNAVVLNNLAWLYLELKDPRALE-YAERAL-----KLAPNIPAILD 841
                         170       180
                  ....*....|....*....|....*....
gi 2130968055 378 TknnLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:TIGR02917 842 T---LGWLLVEKGEADRALPLLRKAVNIA 867
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
205-321 6.51e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.77  E-value: 6.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDLertsgrghPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestl 284
Cdd:COG4235    14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL----- 80
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2130968055 285 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEI 321
Cdd:COG4235    81 ---DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
232-406 7.86e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 7.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 232 KQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRestlgrdhPAVAATLNNLAVLYGKRGKYKEA 311
Cdd:TIGR02917 107 QQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAID--------PRSLYAKLGLAQLALAENRFDEA 178
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 312 EPLCQRALEIrekvlgtdHPDVAKQLNNLALLCQNQGKYEAVERYYRRALaiyegQLGPDNPNVartKNNLASCYLKQGK 391
Cdd:TIGR02917 179 RALIDEVLTA--------DPGNVDALLLKGDLLLSLGNIELALAAYRKAI-----ALRPNNIAV---LLALATILIEAGE 242
                         170
                  ....*....|....*
gi 2130968055 392 YAEAETLYKEILTRA 406
Cdd:TIGR02917 243 FEEAEKHADALLKKA 257
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
163-362 7.90e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.22  E-value: 7.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 163 AEEKEGDATKDSLDDLFPNEEEEDPSNGLSRGQGAQHSGYEI---PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEDle 239
Cdd:COG4785    25 LLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRAlalPDLAQLYYERGVAYDSLGDYDLAIADFDQALEL-- 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 240 rtsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRestlgrdhPAVAATLNNLAVLYGKRGKYKEAEPLCQRAL 319
Cdd:COG4785   103 ------DPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELD--------PDYAYAYLNRGIALYYLGRYELAIADLEKAL 168
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2130968055 320 EIREK----------VLGTDHPDVAKQL--NNLALLCQNQGKYEAVERYYRRALA 362
Cdd:COG4785   169 ELDPNdperalwlylAERKLDPEKALALllEDWATAYLLQGDTEEARELFKLALA 223
TPR_10 pfam13374
Tetratricopeptide repeat;
208-248 9.22e-06

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 42.87  E-value: 9.22e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2130968055 208 LRTLHNLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPD 248
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
205-321 1.25e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.18  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLCKQALEdlertsgrGHPDVATMLNILALVYRDQNKYKEAAHLLNDALsirestl 284
Cdd:COG4783    35 PDNPEAFALLGEILLQLGDLDEAIVLLHEALE--------LDPDEPEARLNLGLALLKAGDYDEALALLEKAL------- 99
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2130968055 285 gRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEI 321
Cdd:COG4783   100 -KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
301-405 1.35e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 48.38  E-value: 1.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 301 LYgKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQGKYEAVER------------------------- 355
Cdd:NF040586  402 LY-LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEAREldedtlerqrrvlglgedhphtlmt 480
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130968055 356 ------------YYRRALAI----YEGQ---LGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTR 405
Cdd:NF040586  481 agglgadlralgRFREALELdeetLERHrrvFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRR 549
TPR_10 pfam13374
Tetratricopeptide repeat;
333-374 1.35e-05

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 42.49  E-value: 1.35e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2130968055 333 VAKQLNNLALLCQNQGKYEAVERYYRRALAIYEGQLGPDNPN 374
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
217-416 2.99e-05

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 46.54  E-value: 2.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 217 QYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALsiresTLGRDHPAVAATLN 296
Cdd:pfam17874  89 ILRAQGRLHQALETYQQALQLARDHGLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGI-----QLGRQWEPDAAVDA 163
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 297 NLAVLYGK--RGKYKEAEPLCQRALEI-REKVLGTDHPDVAKQLNNLALLCQNQgkyeavERYYRRALAIYEGQLGPDNP 373
Cdd:pfam17874 164 YVLLARIAlaQGELEEALTLLRRAELLaRQSFFHVDWLANAERVRVRLWLARGD------LRAAVRWLRAAEPPSDADNH 237
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2130968055 374 NVARTKNNLASCYLKQGKYAEAETLYKEILTRAhlQEFGSVDD 416
Cdd:pfam17874 238 FLERELRNLARVLLALGRFDDALSLLERLQNLA--EQLGRVRS 278
TPR_1 pfam00515
Tetratricopeptide repeat;
292-324 3.08e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.25  E-value: 3.08e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2130968055 292 AATLNNLAVLYGKRGKYKEAEPLCQRALEIREK 324
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
330-407 3.28e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 3.28e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2130968055 330 HPDVAKQLNNLALLCQNQGKYEAVERYYRRALaiyegQLGPDNPNVartKNNLASCYLKQGKYAEAETLYKEILTRAH 407
Cdd:COG4235    13 NPNDAEGWLLLGRAYLRLGRYDEALAAYEKAL-----RLDPDNADA---LLDLAEALLAAGDTEEAEELLERALALDP 82
TPR_12 pfam13424
Tetratricopeptide repeat;
375-493 5.66e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 5.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 375 VARTKNNLASCYLKQGKYAEAETLYKEILTRAHlqefgsvdddhkpiwmhaeereemsksrhREGGTPYTEYGgwykack 454
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIAR-----------------------------RLLGPDHPLTA------- 45
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2130968055 455 vssptvnTTLRNLGALYRRQGKLEAAETLEECALRSQKQ 493
Cdd:pfam13424  46 -------TTLLNLGRLYLELGRYEEALELLERALALAEK 77
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
260-384 9.00e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 42.29  E-value: 9.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 260 YRDQNKYKEAAHLLNDALSirestLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEirekvLGTDHPDVAKQLNN 339
Cdd:COG1729     3 LLKAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLK-----RYPDSPKAPDALLK 72
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2130968055 340 LALLCQNQGKYEAVERYYRRALAIYegqlgPDNPNVARTKNNLAS 384
Cdd:COG1729    73 LGLSYLELGDYDKARATLEELIKKY-----PDSEAAKEARARLAR 112
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
268-403 1.41e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.75  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 268 EAAHLLNDALSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPDVAKQLNNLALLCQNQ 347
Cdd:COG4785     7 ALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSL 86
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2130968055 348 GKYEAVERYYRRALAIyegqlgpdNPNVARTKNNLASCYLKQGKYAEAETLYKEIL 403
Cdd:COG4785    87 GDYDLAIADFDQALEL--------DPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
292-324 1.70e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 1.70e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2130968055  292 AATLNNLAVLYGKRGKYKEAEPLCQRALEIREK 324
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
182-293 3.81e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 43.75  E-value: 3.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 182 EEEEDPSNGLSRGQGAQHsgyeiPARLRTLHNLVIQYAAQGRYEVAvpLCKQALEDLERTSGRG------HPDVATMLNI 255
Cdd:NF040586  710 ELAEAALEGLRERLGPDH-----PYTLAAAVNLANDLAALGDLDAA--LGEEALERLRRLLGEDlragpdHPDTLACAAN 782
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2130968055 256 LALVYRDQNKYKEAAHLLNDALSIRESTLGRDHPAVAA 293
Cdd:NF040586  783 LALDLRATGRTEEAEELRADTLARLRRVLGPDHPDTVA 820
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
339-406 5.35e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.86  E-value: 5.35e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2130968055 339 NLALLCQNQGKYEAVERYYRRALAiyegqLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAA 64
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
232-406 6.73e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 6.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 232 KQALEDLERTSGRgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrestlgrdHPAVAATLNNLAVLYGKRGKYKEA 311
Cdd:TIGR02917 618 NKAVSSFKKLLAL-QPDSALALLLLADAYAVMKNYAKAITSLKRALEL--------KPDNTEAQIGLAQLLLAAKRTESA 688
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 312 EPLCQRALEIREKvlgtdHPDVAKQLNNLALLcqnQGKYEAVERYYRRALAIYEG-----QLG----------------- 369
Cdd:TIGR02917 689 KKIAKSLQKQHPK-----AALGFELEGDLYLR---QKDYPAAIQAYRKALKRAPSsqnaiKLHrallasgntaeavktle 760
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2130968055 370 ---PDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:TIGR02917 761 awlKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKA 800
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
256-321 7.85e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.09  E-value: 7.85e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2130968055 256 LALVYRDQNKYKEAAHLLNDALsiresTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEI 321
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAAL-----ARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRA 63
TPR_1 pfam00515
Tetratricopeptide repeat;
334-365 9.03e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.02  E-value: 9.03e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2130968055 334 AKQLNNLALLCQNQGKYEAVERYYRRALAIYE 365
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
TPR_7 pfam13176
Tetratricopeptide repeat;
294-327 1.14e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 36.75  E-value: 1.14e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2130968055 294 TLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLG 327
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYD 34
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
206-389 1.19e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 41.99  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055  206 ARLRTLHNLviqyaAQGRYEVAVPLCKQALedlertsgRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLG 285
Cdd:PRK11447   272 ARAQGLAAV-----DSGQGGKAIPELQQAV--------RANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPHSSN 338
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055  286 RDHPAVAATLNN--LAVLYG----KRGKYKEAEPLCQRALEIREK----VLGTDhpDVAkqlnnLAllcqnQGKYEAVER 355
Cdd:PRK11447   339 RDKWESLLKVNRywLLIQQGdaalKANNLAQAERLYQQARQVDNTdsyaVLGLG--DVA-----MA-----RKDYAAAER 406
                          170       180       190
                   ....*....|....*....|....*....|....
gi 2130968055  356 YYRRALaiyegQLGPDNPNVARtknNLASCYLKQ 389
Cdd:PRK11447   407 YYQQAL-----RMDPGNTNAVR---GLANLYRQQ 432
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
261-406 1.44e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 41.18  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 261 RDQNKYKEAAHLLNDA--LSIRESTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIREKVLGTDHPdvAKQ-- 336
Cdd:cd24145   114 SELGKWELRERLLKKAveILLKLGELWMSPSEVGAFLEELATAYDLYGRFCLALPLYMQALSLKGQILLSQAN--CHSlv 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 337 -LNNLAL-LCQNQGK---------------------YEAVERYYRRALAIYEgqlgpDNPNVARTKN----------NLA 383
Cdd:cd24145   192 lMNNEAAeLALHALRkplsstlieasrlpqksrdqlLEAALKWAQKALDVAK-----SIKPKDRDPEcdqacalalyNLG 266
                         170       180
                  ....*....|....*....|...
gi 2130968055 384 SCYLKQGKYAEAETLYKEILTRA 406
Cdd:cd24145   267 VIAEMLGNLDEARKLYKEAISLA 289
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
205-284 1.71e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 205 PARLRTLHNLVIQYAAQGRYEVAVPLcKQALEDlertsgrgHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTL 284
Cdd:COG3063    23 PDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALLNLAELLLELGDYDEALAYLERALELDPSAL 93
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
33-148 2.48e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 2.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055   33 LEALHSEHQAVLQSLSHTIECLQQGGHEEGLVHEKARQLRRSMENIELGLSEAQ-VMLALASHLSTVESEKQKLRAQVRR 111
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkELYALANEISRLEQQKQILRERLAN 313
                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2130968055  112 LCQENQWLRDELAGTQQRLQRSEQAVAQLEEEKKHLE 148
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
TPR_1 pfam00515
Tetratricopeptide repeat;
376-403 4.63e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 4.63e-03
                          10        20
                  ....*....|....*....|....*...
gi 2130968055 376 ARTKNNLASCYLKQGKYAEAETLYKEIL 403
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKAL 28
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
376-406 5.59e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 5.59e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 2130968055  376 ARTKNNLASCYLKQGKYAEAETLYKEILTRA 406
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELD 31
TPR_19 pfam14559
Tetratricopeptide repeat;
347-403 5.63e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 35.64  E-value: 5.63e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2130968055 347 QGKYEAVERYYRRALAIYegqlgPDNPNVartKNNLASCYLKQGKYAEAETLYKEIL 403
Cdd:pfam14559   1 EGDYAEALELLEQALAED-----PDNAEA---RLGLAEALLALGRLDEAEALLAALP 49
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
218-277 6.26e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 35.77  E-value: 6.26e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130968055 218 YAAQGRYEVAVPLCKQALEdlertSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDAL 277
Cdd:pfam13432   7 ALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAAL 61
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
334-363 7.37e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 7.37e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 2130968055  334 AKQLNNLALLCQNQGKYEAVERYYRRALAI 363
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALEL 30
TPR_10 pfam13374
Tetratricopeptide repeat;
375-418 7.41e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 34.79  E-value: 7.41e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2130968055 375 VARTKNNLASCYLKQGKYAEAETLYKEILTRAHlQEFGsvdDDH 418
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRE-RVLG---PDH 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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