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Conserved domains on  [gi|2130940412|ref|XP_044910341|]
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Alstrom syndrome protein 1 isoform X5 [Felis catus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ALMS_motif pfam15309
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
 4485-4608 2.19e-58

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


:

Pssm-ID: 464634  Cd Length: 131  Bit Score: 198.75  E-value: 2.19e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 4485 FVKATLQESLQLHRPDFISRSGERIKRLKLIVQERKLQNMLQSEREALFNTVREWQGCQDPTrrLLKRGFLDAQKNRPIG 4564
Cdd:pfam15309    1 LVRLSLQEALEMHRPDFISRSRERLKRLELLVEERKLQEVLQRERERLFNKPIPRTNKRQQT--VPLPDNLFKPRRRAIS 78

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2130940412 4565 KKEMIQRSKRIYEQLPEVQRKREEEKRRLEYKSYRLRAQLFKKR 4608
Cdd:pfam15309   79 KKEMIARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKKK 122
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1370-1416 4.29e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 86.33  E-value: 4.29e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1370 QQELPDSSLTEQAQKVSPVPGPAEQKTGIPTLTSTSYSLGEKPSLFY 1416
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1605-1651 4.29e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 86.33  E-value: 4.29e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1605 QQELPDSSLTEQAQKVSPVPGPAEQKTGIPTLTSTSYSLGEKPSLFY 1651
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1558-1603 4.91e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 85.94  E-value: 4.91e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1558 QQELPDSHLTEQAQKVSPVTGPAEQKTGIPTLTSASHSHREKPNLF 1603
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1793-1839 3.19e-19

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 83.63  E-value: 3.19e-19
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1793 QQELPDSHLTEQAQKLSLVPGPADQKTEISTVTSASYSHIEKPFIFY 1839
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1841-1886 2.80e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 80.93  E-value: 2.80e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1841 QDLPDSHLSQESLKVTAVSEPVDKKTGIPVVPSTSYSQREKPIIFY 1886
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1464-1510 5.76e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 80.16  E-value: 5.76e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1464 QQVLPDSHLTEETLKASSAPRPGDAKTGVPTVPSSSYSPREKSGIFY 1510
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1699-1745 8.59e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 79.78  E-value: 8.59e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1699 QQVLPDSHLTEETLKASSAPRPGDAKTGVPTVPSNSYSPREKSGIFY 1745
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1323-1368 2.23e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 78.62  E-value: 2.23e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1323 QQELPDSSLTEQAQKVSPVTGSAEQKTGIPTLTSASHSHREKPNLF 1368
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1229-1275 3.02e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 78.24  E-value: 3.02e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1229 QQALPDSHLIEQAQKVSAVPGPVDQKTRIPAASSTYYSYGERPQIFY 1275
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1276-1321 4.17e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 77.85  E-value: 4.17e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1276 QQTLPESHLPEQALKFSAAPGSYEQKTGIPTVTSTPYSHREKLNLF 1321
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2076-2121 2.19e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.54  E-value: 2.19e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2076 QGLTDSQIPQEALKVSAVRGPADQKTGLPSESSSPYSHREKPIIFY 2121
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2312-2356 3.29e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.29e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2312 QQELPD--LTQEALKVLKVPGLGGQKTGIPAVTSTFYSHREKPIISY 2356
Cdd:pfam18727    1 QQELPDshLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2123-2168 3.56e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.56e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2123 QGLTGSQVPLEALKASAVPGPADQKTGLPSEPSSSYSHREKPIIFY 2168
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1089-1134 3.67e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.67e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1089 QYLPDRHLTEEAPKVLAVLGPADQKTGIPTVFPSSYPLGEKHGIFY 1134
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2170-2215 7.33e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 74.00  E-value: 7.33e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2170 QDLTDSQVPQEALKVSAVPGPADQKTGLPSEPSSSYSLGGKPVIFY 2215
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2263-2311 2.06e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 72.84  E-value: 2.06e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2130940412 2263 QQPLSDSQLPVEALKVSAVSGPGDQKTRKPTVTSTSYSHRekEKPIISY 2311
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHR--EKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2029-2074 3.39e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 72.07  E-value: 3.39e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2029 QGLTDSQVPQEALKVSTVPGRADQKTGLPSELSSSYSHREKPIIFS 2074
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1182-1228 8.48e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 71.30  E-value: 8.48e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1182 QQQSSDSHLTEQALKVSVVSGPAGENTGIPILPSVSSSLGEKPSVFY 1228
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2216-2262 1.32e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 70.53  E-value: 1.32e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2216 QQALSDRHLTEEAVNISASPGPADQETRVSTVPSISYSHIEKPNVLY 2262
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1935-1980 4.00e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 69.38  E-value: 4.00e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1935 QALAGSLLLEEALKVSVLPGPADQKAGLSSEPPSSYSHGEKPIIFY 1980
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1042-1086 4.28e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.99  E-value: 4.28e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1042 QQAL-DSHTTEKTLKVSTVHELADQKTGISTVPSSSYSQRGKPGIF 1086
Cdd:pfam18727    1 QQELpDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1888-1933 5.11e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.99  E-value: 5.11e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1888 QAIPDIHLTEEALKVSAISGSADWKTGIPTVSSISSSHTEEPVSFS 1933
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2584-2629 6.39e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.61  E-value: 6.39e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2584 QELPDKHLAEDALNISSIPVPADQKSLLPTAPPGSFSHREKPNLFY 2629
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2447-2490 4.01e-13

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 66.30  E-value: 4.01e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2447 QQELPD--VTEKVLKVFALPGPADQKTEIPTGPSSSYSHKEKLNIS 2490
Cdd:pfam18727    1 QQELPDshLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1652-1698 5.32e-13

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 65.91  E-value: 5.32e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1652 QQELPDNPLTEQAQKVLAIPGPDDQNTGISIGSSRPYSLGEQPSIFS 1698
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1417-1463 1.18e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 65.14  E-value: 1.18e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1417 QQELPDNPLTEQAQKVLAIPGPDDQNTGISIGSSRPYSLGEQPNIFS 1463
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1136-1181 2.23e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 64.37  E-value: 2.23e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1136 QALPDSYVTEEALKVSAVPVSADQRTEKITVPSTSYLQREKHVNFS 1181
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1982-2026 2.59e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 63.98  E-value: 2.59e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2130940412 1982 QGLTDSQVPQETLEVSAVPGPAAQKTGLPSEPSSCDSHKEKPIIF 2026
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1746-1792 7.88e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 62.83  E-value: 7.88e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1746 QQVLPGCHLSEEALKVSVATVPAEIKSGLPSEASSFYTEREKTSIFY 1792
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1511-1557 1.18e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 62.06  E-value: 1.18e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1511 QQVLPGCHLSEEALKVSVATVPAEIKSGLPSEASNFYTEREKTSIFY 1557
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2358-2401 2.40e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 61.29  E-value: 2.40e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2358 QELSDPN--EGALRVLGTPGPADQKTGIQIGPSTSYSHRESPIFSY 2401
Cdd:pfam18727    2 QELPDSHltEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2406-2446 4.71e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 60.52  E-value: 4.71e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 2130940412 2406 SDITEETWKVSPVSGPANQKTEIHIIPSSSYSYREKDSILY 2446
Cdd:pfam18727    7 SHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2630-2676 9.21e-10

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 56.67  E-value: 9.21e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2630 QQDFPDRHLPEDSVMFSRGLGQADQITGLSTVTPGTYSHSEKQKLVS 2676
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat super family cl40041
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2546-2582 1.22e-03

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


The actual alignment was detected with superfamily member pfam18727:

Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 39.72  E-value: 1.22e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2130940412 2546 EDILKISPVPEPIVVNSGIPIPLSSSSSHREKSNIFY 2582
Cdd:pfam18727   11 EEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
Tubulin_FtsZ_Cetz-like super family cl10017
Tubulin protein family of FtsZ and CetZ-like; This family includes tubulin alpha-, beta-, ...
 3487-3711 4.10e-03

Tubulin protein family of FtsZ and CetZ-like; This family includes tubulin alpha-, beta-, gamma-, delta-, epsilon, and zeta-tubulins as well as FtsZ and CetZ, all of which are involved in polymer formation. Tubulin is the major component of microtubules, but also exists as a heterodimer and as a curved oligomer. Microtubules exist in all eukaryotic cells and are responsible for many functions, including cellular transport, cell motility, and mitosis. FtsZ forms a ring-shaped septum at the site of bacterial cell division, which is required for constriction of cell membrane and cell envelope to yield two daughter cells. FtsZ can polymerize into tubes, sheets, and rings in vitro and is ubiquitous in eubacteria, archaea, and chloroplasts. A recent study found that CetZ proteins, formerly annotated FtsZ type 2, are not required for cell division, whereas FtsZ proteins play an important role. Instead, CetZ proteins are shown to be involved in controlling archaeal cell shape dynamics. The results from inactivation studies of CetZ proteins in Haloferax volcanii suggest that CetZ1 is essential for normal swimming motility and rod-cell development.


The actual alignment was detected with superfamily member cd06060:

Pssm-ID: 471962 [Multi-domain]  Cd Length: 539  Bit Score: 43.46  E-value: 4.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 3487 NQCTLVTSASTPPSNRKAlscvritlyPKTPSKVDSGTLDRRLHS-------LDPAS-KTRMNSEFNSDLQTISSRSlep 3558
Cdd:cd06060    274 EHSSLFVPLSLPSLLWRK---------PGWPRTFPHLDYSSPYHTsavlaaaLDTATlPYRLKSSSVSMSDLCSSLT--- 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 3559 tsklSASKPVAQNQESLGFLGLKSSPDFQVVQSPLPD-SNTISQDLKTIPFqnSQIVTSRqtqvNISDLEGYSSPEGI-P 3636
Cdd:cd06060    342 ----FSGRKVAALSLALPFPLLLGSSLLDSLQDLLGDlSLTPSCQNETDVF--AQSVVLR----GIPESRLKSPLQPRsP 411

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130940412 3637 VSADRLSEEIKTPFSAFSGKLSSDAVTQITTESPGKTTFSSEIFINAEDHGFESPE--PSTQNVDKVPV--KFVSSSSV 3711
Cdd:cd06060    412 ASRCSSVEEVLEGYLQCTFPGSSSAVTTLPQPLPVPTPFPSIFSPSLGRKGFLLDDsrPASLDVESVPVlaSLQSSSAL 490
 
Name Accession Description Interval E-value
ALMS_motif pfam15309
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
 4485-4608 2.19e-58

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


Pssm-ID: 464634  Cd Length: 131  Bit Score: 198.75  E-value: 2.19e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 4485 FVKATLQESLQLHRPDFISRSGERIKRLKLIVQERKLQNMLQSEREALFNTVREWQGCQDPTrrLLKRGFLDAQKNRPIG 4564
Cdd:pfam15309    1 LVRLSLQEALEMHRPDFISRSRERLKRLELLVEERKLQEVLQRERERLFNKPIPRTNKRQQT--VPLPDNLFKPRRRAIS 78

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2130940412 4565 KKEMIQRSKRIYEQLPEVQRKREEEKRRLEYKSYRLRAQLFKKR 4608
Cdd:pfam15309   79 KKEMIARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKKK 122
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1370-1416 4.29e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 86.33  E-value: 4.29e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1370 QQELPDSSLTEQAQKVSPVPGPAEQKTGIPTLTSTSYSLGEKPSLFY 1416
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1605-1651 4.29e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 86.33  E-value: 4.29e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1605 QQELPDSSLTEQAQKVSPVPGPAEQKTGIPTLTSTSYSLGEKPSLFY 1651
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1558-1603 4.91e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 85.94  E-value: 4.91e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1558 QQELPDSHLTEQAQKVSPVTGPAEQKTGIPTLTSASHSHREKPNLF 1603
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1793-1839 3.19e-19

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 83.63  E-value: 3.19e-19
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1793 QQELPDSHLTEQAQKLSLVPGPADQKTEISTVTSASYSHIEKPFIFY 1839
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1841-1886 2.80e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 80.93  E-value: 2.80e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1841 QDLPDSHLSQESLKVTAVSEPVDKKTGIPVVPSTSYSQREKPIIFY 1886
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1464-1510 5.76e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 80.16  E-value: 5.76e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1464 QQVLPDSHLTEETLKASSAPRPGDAKTGVPTVPSSSYSPREKSGIFY 1510
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1699-1745 8.59e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 79.78  E-value: 8.59e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1699 QQVLPDSHLTEETLKASSAPRPGDAKTGVPTVPSNSYSPREKSGIFY 1745
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1323-1368 2.23e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 78.62  E-value: 2.23e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1323 QQELPDSSLTEQAQKVSPVTGSAEQKTGIPTLTSASHSHREKPNLF 1368
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1229-1275 3.02e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 78.24  E-value: 3.02e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1229 QQALPDSHLIEQAQKVSAVPGPVDQKTRIPAASSTYYSYGERPQIFY 1275
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1276-1321 4.17e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 77.85  E-value: 4.17e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1276 QQTLPESHLPEQALKFSAAPGSYEQKTGIPTVTSTPYSHREKLNLF 1321
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2076-2121 2.19e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.54  E-value: 2.19e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2076 QGLTDSQIPQEALKVSAVRGPADQKTGLPSESSSPYSHREKPIIFY 2121
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2312-2356 3.29e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.29e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2312 QQELPD--LTQEALKVLKVPGLGGQKTGIPAVTSTFYSHREKPIISY 2356
Cdd:pfam18727    1 QQELPDshLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2123-2168 3.56e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.56e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2123 QGLTGSQVPLEALKASAVPGPADQKTGLPSEPSSSYSHREKPIIFY 2168
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1089-1134 3.67e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.67e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1089 QYLPDRHLTEEAPKVLAVLGPADQKTGIPTVFPSSYPLGEKHGIFY 1134
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2170-2215 7.33e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 74.00  E-value: 7.33e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2170 QDLTDSQVPQEALKVSAVPGPADQKTGLPSEPSSSYSLGGKPVIFY 2215
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2263-2311 2.06e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 72.84  E-value: 2.06e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2130940412 2263 QQPLSDSQLPVEALKVSAVSGPGDQKTRKPTVTSTSYSHRekEKPIISY 2311
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHR--EKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2029-2074 3.39e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 72.07  E-value: 3.39e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2029 QGLTDSQVPQEALKVSTVPGRADQKTGLPSELSSSYSHREKPIIFS 2074
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1182-1228 8.48e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 71.30  E-value: 8.48e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1182 QQQSSDSHLTEQALKVSVVSGPAGENTGIPILPSVSSSLGEKPSVFY 1228
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2216-2262 1.32e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 70.53  E-value: 1.32e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2216 QQALSDRHLTEEAVNISASPGPADQETRVSTVPSISYSHIEKPNVLY 2262
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1935-1980 4.00e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 69.38  E-value: 4.00e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1935 QALAGSLLLEEALKVSVLPGPADQKAGLSSEPPSSYSHGEKPIIFY 1980
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1042-1086 4.28e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.99  E-value: 4.28e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1042 QQAL-DSHTTEKTLKVSTVHELADQKTGISTVPSSSYSQRGKPGIF 1086
Cdd:pfam18727    1 QQELpDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1888-1933 5.11e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.99  E-value: 5.11e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1888 QAIPDIHLTEEALKVSAISGSADWKTGIPTVSSISSSHTEEPVSFS 1933
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2584-2629 6.39e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.61  E-value: 6.39e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2584 QELPDKHLAEDALNISSIPVPADQKSLLPTAPPGSFSHREKPNLFY 2629
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2447-2490 4.01e-13

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 66.30  E-value: 4.01e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2447 QQELPD--VTEKVLKVFALPGPADQKTEIPTGPSSSYSHKEKLNIS 2490
Cdd:pfam18727    1 QQELPDshLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1652-1698 5.32e-13

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 65.91  E-value: 5.32e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1652 QQELPDNPLTEQAQKVLAIPGPDDQNTGISIGSSRPYSLGEQPSIFS 1698
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1417-1463 1.18e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 65.14  E-value: 1.18e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1417 QQELPDNPLTEQAQKVLAIPGPDDQNTGISIGSSRPYSLGEQPNIFS 1463
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1136-1181 2.23e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 64.37  E-value: 2.23e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1136 QALPDSYVTEEALKVSAVPVSADQRTEKITVPSTSYLQREKHVNFS 1181
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1982-2026 2.59e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 63.98  E-value: 2.59e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2130940412 1982 QGLTDSQVPQETLEVSAVPGPAAQKTGLPSEPSSCDSHKEKPIIF 2026
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1746-1792 7.88e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 62.83  E-value: 7.88e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1746 QQVLPGCHLSEEALKVSVATVPAEIKSGLPSEASSFYTEREKTSIFY 1792
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1511-1557 1.18e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 62.06  E-value: 1.18e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1511 QQVLPGCHLSEEALKVSVATVPAEIKSGLPSEASNFYTEREKTSIFY 1557
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2358-2401 2.40e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 61.29  E-value: 2.40e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2358 QELSDPN--EGALRVLGTPGPADQKTGIQIGPSTSYSHRESPIFSY 2401
Cdd:pfam18727    2 QELPDSHltEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2406-2446 4.71e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 60.52  E-value: 4.71e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 2130940412 2406 SDITEETWKVSPVSGPANQKTEIHIIPSSSYSYREKDSILY 2446
Cdd:pfam18727    7 SHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2630-2676 9.21e-10

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 56.67  E-value: 9.21e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2630 QQDFPDRHLPEDSVMFSRGLGQADQITGLSTVTPGTYSHSEKQKLVS 2676
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2546-2582 1.22e-03

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 39.72  E-value: 1.22e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2130940412 2546 EDILKISPVPEPIVVNSGIPIPLSSSSSHREKSNIFY 2582
Cdd:pfam18727   11 EEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
misato cd06060
Misato segment II tubulin-like domain; Human Misato shows similarity with Tubulin/FtsZ family ...
 3487-3711 4.10e-03

Misato segment II tubulin-like domain; Human Misato shows similarity with Tubulin/FtsZ family of GTPases and is localized to the the outer membrane of mitochondria. It has a role in mitochondrial fusion and in mitochondrial distribution and morphology. Mutations in its Drosophila homolog (misato) lead to irregular chromosome segregation during mitosis. Deletion of the budding yeast homolog DML1 is lethal and unregulate expression of DML1 leads to mitochondrial dispersion and abnormalities in cell morphology. The Misato/DML1 protein family is conserved from yeast to human, but its exact function is still unknown.


Pssm-ID: 276964 [Multi-domain]  Cd Length: 539  Bit Score: 43.46  E-value: 4.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 3487 NQCTLVTSASTPPSNRKAlscvritlyPKTPSKVDSGTLDRRLHS-------LDPAS-KTRMNSEFNSDLQTISSRSlep 3558
Cdd:cd06060    274 EHSSLFVPLSLPSLLWRK---------PGWPRTFPHLDYSSPYHTsavlaaaLDTATlPYRLKSSSVSMSDLCSSLT--- 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 3559 tsklSASKPVAQNQESLGFLGLKSSPDFQVVQSPLPD-SNTISQDLKTIPFqnSQIVTSRqtqvNISDLEGYSSPEGI-P 3636
Cdd:cd06060    342 ----FSGRKVAALSLALPFPLLLGSSLLDSLQDLLGDlSLTPSCQNETDVF--AQSVVLR----GIPESRLKSPLQPRsP 411

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130940412 3637 VSADRLSEEIKTPFSAFSGKLSSDAVTQITTESPGKTTFSSEIFINAEDHGFESPE--PSTQNVDKVPV--KFVSSSSV 3711
Cdd:cd06060    412 ASRCSSVEEVLEGYLQCTFPGSSSAVTTLPQPLPVPTPFPSIFSPSLGRKGFLLDDsrPASLDVESVPVlaSLQSSSAL 490
 
Name Accession Description Interval E-value
ALMS_motif pfam15309
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
 4485-4608 2.19e-58

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


Pssm-ID: 464634  Cd Length: 131  Bit Score: 198.75  E-value: 2.19e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 4485 FVKATLQESLQLHRPDFISRSGERIKRLKLIVQERKLQNMLQSEREALFNTVREWQGCQDPTrrLLKRGFLDAQKNRPIG 4564
Cdd:pfam15309    1 LVRLSLQEALEMHRPDFISRSRERLKRLELLVEERKLQEVLQRERERLFNKPIPRTNKRQQT--VPLPDNLFKPRRRAIS 78

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2130940412 4565 KKEMIQRSKRIYEQLPEVQRKREEEKRRLEYKSYRLRAQLFKKR 4608
Cdd:pfam15309   79 KKEMIARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKKK 122
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1370-1416 4.29e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 86.33  E-value: 4.29e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1370 QQELPDSSLTEQAQKVSPVPGPAEQKTGIPTLTSTSYSLGEKPSLFY 1416
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1605-1651 4.29e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 86.33  E-value: 4.29e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1605 QQELPDSSLTEQAQKVSPVPGPAEQKTGIPTLTSTSYSLGEKPSLFY 1651
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1558-1603 4.91e-20

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 85.94  E-value: 4.91e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1558 QQELPDSHLTEQAQKVSPVTGPAEQKTGIPTLTSASHSHREKPNLF 1603
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1793-1839 3.19e-19

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 83.63  E-value: 3.19e-19
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1793 QQELPDSHLTEQAQKLSLVPGPADQKTEISTVTSASYSHIEKPFIFY 1839
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1841-1886 2.80e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 80.93  E-value: 2.80e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1841 QDLPDSHLSQESLKVTAVSEPVDKKTGIPVVPSTSYSQREKPIIFY 1886
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1464-1510 5.76e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 80.16  E-value: 5.76e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1464 QQVLPDSHLTEETLKASSAPRPGDAKTGVPTVPSSSYSPREKSGIFY 1510
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1699-1745 8.59e-18

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 79.78  E-value: 8.59e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1699 QQVLPDSHLTEETLKASSAPRPGDAKTGVPTVPSNSYSPREKSGIFY 1745
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1323-1368 2.23e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 78.62  E-value: 2.23e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1323 QQELPDSSLTEQAQKVSPVTGSAEQKTGIPTLTSASHSHREKPNLF 1368
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1229-1275 3.02e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 78.24  E-value: 3.02e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1229 QQALPDSHLIEQAQKVSAVPGPVDQKTRIPAASSTYYSYGERPQIFY 1275
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1276-1321 4.17e-17

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 77.85  E-value: 4.17e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1276 QQTLPESHLPEQALKFSAAPGSYEQKTGIPTVTSTPYSHREKLNLF 1321
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2076-2121 2.19e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.54  E-value: 2.19e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2076 QGLTDSQIPQEALKVSAVRGPADQKTGLPSESSSPYSHREKPIIFY 2121
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2312-2356 3.29e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.29e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2312 QQELPD--LTQEALKVLKVPGLGGQKTGIPAVTSTFYSHREKPIISY 2356
Cdd:pfam18727    1 QQELPDshLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2123-2168 3.56e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.56e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2123 QGLTGSQVPLEALKASAVPGPADQKTGLPSEPSSSYSHREKPIIFY 2168
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1089-1134 3.67e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 75.16  E-value: 3.67e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1089 QYLPDRHLTEEAPKVLAVLGPADQKTGIPTVFPSSYPLGEKHGIFY 1134
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2170-2215 7.33e-16

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 74.00  E-value: 7.33e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2170 QDLTDSQVPQEALKVSAVPGPADQKTGLPSEPSSSYSLGGKPVIFY 2215
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2263-2311 2.06e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 72.84  E-value: 2.06e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2130940412 2263 QQPLSDSQLPVEALKVSAVSGPGDQKTRKPTVTSTSYSHRekEKPIISY 2311
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHR--EKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2029-2074 3.39e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 72.07  E-value: 3.39e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2029 QGLTDSQVPQEALKVSTVPGRADQKTGLPSELSSSYSHREKPIIFS 2074
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1182-1228 8.48e-15

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 71.30  E-value: 8.48e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1182 QQQSSDSHLTEQALKVSVVSGPAGENTGIPILPSVSSSLGEKPSVFY 1228
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2216-2262 1.32e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 70.53  E-value: 1.32e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2216 QQALSDRHLTEEAVNISASPGPADQETRVSTVPSISYSHIEKPNVLY 2262
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1935-1980 4.00e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 69.38  E-value: 4.00e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1935 QALAGSLLLEEALKVSVLPGPADQKAGLSSEPPSSYSHGEKPIIFY 1980
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1042-1086 4.28e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.99  E-value: 4.28e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1042 QQAL-DSHTTEKTLKVSTVHELADQKTGISTVPSSSYSQRGKPGIF 1086
Cdd:pfam18727    1 QQELpDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1888-1933 5.11e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.99  E-value: 5.11e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1888 QAIPDIHLTEEALKVSAISGSADWKTGIPTVSSISSSHTEEPVSFS 1933
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2584-2629 6.39e-14

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 68.61  E-value: 6.39e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2584 QELPDKHLAEDALNISSIPVPADQKSLLPTAPPGSFSHREKPNLFY 2629
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2447-2490 4.01e-13

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 66.30  E-value: 4.01e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2447 QQELPD--VTEKVLKVFALPGPADQKTEIPTGPSSSYSHKEKLNIS 2490
Cdd:pfam18727    1 QQELPDshLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1652-1698 5.32e-13

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 65.91  E-value: 5.32e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1652 QQELPDNPLTEQAQKVLAIPGPDDQNTGISIGSSRPYSLGEQPSIFS 1698
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1417-1463 1.18e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 65.14  E-value: 1.18e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1417 QQELPDNPLTEQAQKVLAIPGPDDQNTGISIGSSRPYSLGEQPNIFS 1463
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1136-1181 2.23e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 64.37  E-value: 2.23e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 1136 QALPDSYVTEEALKVSAVPVSADQRTEKITVPSTSYLQREKHVNFS 1181
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1982-2026 2.59e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 63.98  E-value: 2.59e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2130940412 1982 QGLTDSQVPQETLEVSAVPGPAAQKTGLPSEPSSCDSHKEKPIIF 2026
Cdd:pfam18727    2 QELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIF 46
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1746-1792 7.88e-12

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 62.83  E-value: 7.88e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1746 QQVLPGCHLSEEALKVSVATVPAEIKSGLPSEASSFYTEREKTSIFY 1792
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 1511-1557 1.18e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 62.06  E-value: 1.18e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 1511 QQVLPGCHLSEEALKVSVATVPAEIKSGLPSEASNFYTEREKTSIFY 1557
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2358-2401 2.40e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 61.29  E-value: 2.40e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 2130940412 2358 QELSDPN--EGALRVLGTPGPADQKTGIQIGPSTSYSHRESPIFSY 2401
Cdd:pfam18727    2 QELPDSHltEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2406-2446 4.71e-11

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 60.52  E-value: 4.71e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 2130940412 2406 SDITEETWKVSPVSGPANQKTEIHIIPSSSYSYREKDSILY 2446
Cdd:pfam18727    7 SHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2630-2676 9.21e-10

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 56.67  E-value: 9.21e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2130940412 2630 QQDFPDRHLPEDSVMFSRGLGQADQITGLSTVTPGTYSHSEKQKLVS 2676
Cdd:pfam18727    1 QQELPDSHLTEEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
ALMS_repeat pfam18727
Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It ...
 2546-2582 1.22e-03

Alstrom syndrome repeat; This entry contains a single repeat unit of approximately 47 AA. It is found in Alstrom syndrome protein 1 (ALMS1) and homologs.


Pssm-ID: 376150 [Multi-domain]  Cd Length: 47  Bit Score: 39.72  E-value: 1.22e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 2130940412 2546 EDILKISPVPEPIVVNSGIPIPLSSSSSHREKSNIFY 2582
Cdd:pfam18727   11 EEALKVSAVPGPADQKTGIPTVTSSSYSHREKPSIFY 47
misato cd06060
Misato segment II tubulin-like domain; Human Misato shows similarity with Tubulin/FtsZ family ...
 3487-3711 4.10e-03

Misato segment II tubulin-like domain; Human Misato shows similarity with Tubulin/FtsZ family of GTPases and is localized to the the outer membrane of mitochondria. It has a role in mitochondrial fusion and in mitochondrial distribution and morphology. Mutations in its Drosophila homolog (misato) lead to irregular chromosome segregation during mitosis. Deletion of the budding yeast homolog DML1 is lethal and unregulate expression of DML1 leads to mitochondrial dispersion and abnormalities in cell morphology. The Misato/DML1 protein family is conserved from yeast to human, but its exact function is still unknown.


Pssm-ID: 276964 [Multi-domain]  Cd Length: 539  Bit Score: 43.46  E-value: 4.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 3487 NQCTLVTSASTPPSNRKAlscvritlyPKTPSKVDSGTLDRRLHS-------LDPAS-KTRMNSEFNSDLQTISSRSlep 3558
Cdd:cd06060    274 EHSSLFVPLSLPSLLWRK---------PGWPRTFPHLDYSSPYHTsavlaaaLDTATlPYRLKSSSVSMSDLCSSLT--- 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130940412 3559 tsklSASKPVAQNQESLGFLGLKSSPDFQVVQSPLPD-SNTISQDLKTIPFqnSQIVTSRqtqvNISDLEGYSSPEGI-P 3636
Cdd:cd06060    342 ----FSGRKVAALSLALPFPLLLGSSLLDSLQDLLGDlSLTPSCQNETDVF--AQSVVLR----GIPESRLKSPLQPRsP 411

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130940412 3637 VSADRLSEEIKTPFSAFSGKLSSDAVTQITTESPGKTTFSSEIFINAEDHGFESPE--PSTQNVDKVPV--KFVSSSSV 3711
Cdd:cd06060    412 ASRCSSVEEVLEGYLQCTFPGSSSAVTTLPQPLPVPTPFPSIFSPSLGRKGFLLDDsrPASLDVESVPVlaSLQSSSAL 490
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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