|
Name |
Accession |
Description |
Interval |
E-value |
| Glyco_transf_24 |
pfam18404 |
Glucosyltransferase 24; This is the catalytic domain found in UDP-glucose:glycoprotein ... |
1167-1434 |
0e+00 |
|
Glucosyltransferase 24; This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
:
Pssm-ID: 436473 Cd Length: 268 Bit Score: 630.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHLYERMLNIMMVSVMRNTKHTVKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREI 1246
Cdd:pfam18404 1 INIFSVASGHLYERFLKIMMLSVRKNTKSPVKFWFIENFLSPSFKAFLPHLAKEYGFEYELVTYKWPSWLRKQTEKQRII 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1247 WGYKILFLDVLFPLSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGFTPMCDSRTEMEGFRFWKQGYWANYLRGLPYHIS 1326
Cdd:pfam18404 81 WGYKILFLDVLFPLDLDKVIFVDADQVVRTDLKELVDMDLEGAPYGYTPMCDSRKEMEGFRFWKQGYWKDHLRGRPYHIS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1327 ALYVVDLNRFRQLAAGDRLRQQYHALSADPNSLSNLDQDLPNNMQFTIPIHSLPQEWLWCETWCSDESLAQARTIDLCNN 1406
Cdd:pfam18404 161 ALYVVDLKRFRQMAAGDRLRSHYQQLSADPNSLANLDQDLPNNMQHQVPIFSLPQEWLWCETWCSDESLKKAKTIDLCNN 240
|
250 260
....*....|....*....|....*...
gi 2124654928 1407 PQTKEPKLDRARRQVPEWTLYDEEIAAL 1434
Cdd:pfam18404 241 PLTKEPKLDRAKRIIPEWTDYDEEVAAL 268
|
|
| Thioredoxin_14 |
pfam18402 |
Thioredoxin-like domain; This is the third out of four TRXL(thioredoxin-like) domains found in ... |
402-644 |
1.35e-89 |
|
Thioredoxin-like domain; This is the third out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
:
Pssm-ID: 465750 Cd Length: 248 Bit Score: 291.10 E-value: 1.35e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 402 FDWTDRLEEGKALLWLNDLEKDARYQKLPSDLTALLQRTYPGQLPQVALNLFHIVAPVDFTNIEDGR-AFGQLAQFMQRG 480
Cdd:pfam18402 1 FDIRDRIEGGGVIIWLNDLEKDKRYSRWPSSLQELLRPTYPGQLPPIRKNLFNLVLVVDLSQPEDLLlLVETLQSFVQRG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 481 VTLRFGILPLV-TTPASAAQAKVVYHLMETYGFESLITYLQESEE---GPEGAANKKAFTRAIDGRETLPgaNKMTLAEI 556
Cdd:pfam18402 81 IPVRFGLVPLVnSTEDGLAQAKLFYYLLENYGLKAALSFLTASLYalaKKVLSPTKAIFSSALKERTLRP--QALSFDEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 557 LEADTYKQRVEASKAWANRLNADTTVRPVFVNGLAIPREKSWVQAMGQRLTEDQQAIQKAVYFGQIEEGTPVSDLF--LR 634
Cdd:pfam18402 159 LKSEVYDERLKKAKEYLKRLGLDSLSGPVFVNGVPLPRDENWLQALSQRISEDLQLLQKAVYEGALTDDDDVPDFFydLP 238
|
250
....*....|
gi 2124654928 635 DAISKRNTYI 644
Cdd:pfam18402 239 NALPRRNPLI 248
|
|
| Thioredoxin_15 |
pfam18403 |
Thioredoxin-like domain; This is the fourth TRXL(thioredoxin-like) domain found in UDP-glucose: ... |
656-851 |
3.69e-64 |
|
Thioredoxin-like domain; This is the fourth TRXL(thioredoxin-like) domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
:
Pssm-ID: 465751 Cd Length: 205 Bit Score: 216.71 E-value: 3.69e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 656 DINKLHKDFVGLFGNIAVLPSDSkaPKESWAVLTAVADLATDDGQDLLLAALEFKRKNPGVRLDLVHNPPSSAEAH-VIN 734
Cdd:pfam18403 1 DLNKLYSEHADLFDKMPYLEASS--DKEDWATLWVVADLDSESGRKLLLSALEFRKSNPGVRLGIIHNPASPSEASsLIS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 735 GAFKLNEGKLAEMKNKDDLKAILEA----------SWTAEDDGLGTALADFLSASNILPGTKGLLLNGRVVGPLPSDVSF 804
Cdd:pfam18403 79 SALLAALLKLKNLDALEFLTKLLEEeeaaasesgkSSAEAAADYWKALQPFLRVLGLKPGQNALVLNGRVVGPIPEDEEF 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2124654928 805 NEDDLQQLLEFERRNRILPVYAAIKDLGFEDKLSDPIAAAKLTSITA 851
Cdd:pfam18403 159 SADDFELLLSYERSKRIEPVYKAIEELGLEDKISDPDAVAKLTSLVA 205
|
|
| Thioredoxin_12 |
pfam18400 |
Thioredoxin-like domain; This is one of four TRXL(thioredoxin-like) domains found in ... |
36-215 |
7.47e-61 |
|
Thioredoxin-like domain; This is one of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
:
Pssm-ID: 465748 Cd Length: 187 Bit Score: 206.32 E-value: 7.47e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 36 PYLLELLETAAGENSTAYFPLLDKIAG--GHFQSTNSDAELYDRFLEVLQQdgHITkPEALSTYKLALSLRVAAPRIEAH 113
Cdd:pfam18400 3 PLLLEALETLAEENPDLFFPFLDALTNldGEFADASTDEELYEAALKLASD--HLS-PLALSLFKLALSLRSASPRIEAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 114 YQYYTtavDSVSKGDTNDDCSTWALIDNKKYCS-ETLGKAVEGDFSAR-QVNLLPFDRVLGFGKD---AILYADPTSASF 188
Cdd:pfam18400 80 YQIYA---ESVSFEGAPPECDSWVDWGGEVYCDpEDLDALLKSEASSRpQPELLPFDHVYPDSGSspvAILYADLGSPNF 156
|
170 180
....*....|....*....|....*..
gi 2124654928 189 GPFHIALSKAAKQGDVSYRLRYRRSAG 215
Cdd:pfam18400 157 REFHKYLSELAKDGKIRYVLRHVPPSG 183
|
|
| UDP-g_GGTase |
pfam06427 |
UDP-glucose:Glycoprotein Glucosyltransferase; This domain consists of 7 stranded ... |
1021-1129 |
1.58e-60 |
|
UDP-glucose:Glycoprotein Glucosyltransferase; This domain consists of 7 stranded beta-sandwiches found in UDP-glucose-glycoprotein glucosyltransferase-like proteins. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.
:
Pssm-ID: 461910 Cd Length: 109 Bit Score: 202.33 E-value: 1.58e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1021 EGHSRDGKRGA-PRGAQLSLATEKEPLITDTIVMANLGYFQFKANPGFYNIQLKQGRTSKIFTIESVGAHGYaPVPGDEG 1099
Cdd:pfam06427 1 EGHARDVTTGSpPRGLQLVLGTEKNPHVADTIVMANLGYFQLKANPGVWKLELREGRSSDIYEIESVGAEGW-PSPGDEG 79
|
90 100 110
....*....|....*....|....*....|
gi 2124654928 1100 TEIALMDFKGTTLYPRLNRKPGMEEVDVLE 1129
Cdd:pfam06427 80 TEVALTSFEGLTLYPRLSRKPGMENEDVLE 109
|
|
| Thioredoxin_13 |
pfam18401 |
Thioredoxin-like domain; This is the second out of four TRXL(thioredoxin-like) domains found ... |
264-397 |
2.37e-56 |
|
Thioredoxin-like domain; This is the second out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
:
Pssm-ID: 465749 Cd Length: 136 Bit Score: 191.63 E-value: 2.37e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 264 EEVADLKPLSTSELASLGLKTASFILNSENPLDALVKSTQDFPKFSASIATHEVAKEFAAEQEKNVAAGIPSGINFLWMN 343
Cdd:pfam18401 1 EEVEDLKPLSVWELQDLGLQAAQFIMSSDDPLDTLLKLSQDFPKYASSLARHNVSDELREEIEENQERLLPPGDNALWLN 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2124654928 344 GVQLIERQIEPFTLIEMIRRERKLIDGVRDLGFNGQQANSLLGHSEVASSKAED 397
Cdd:pfam18401 81 GLQLDERDIDPFSLLDILRRERKLINGLRKLGLSGSEAVDLLSHPALAAAQADS 134
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Glyco_transf_24 |
pfam18404 |
Glucosyltransferase 24; This is the catalytic domain found in UDP-glucose:glycoprotein ... |
1167-1434 |
0e+00 |
|
Glucosyltransferase 24; This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
Pssm-ID: 436473 Cd Length: 268 Bit Score: 630.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHLYERMLNIMMVSVMRNTKHTVKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREI 1246
Cdd:pfam18404 1 INIFSVASGHLYERFLKIMMLSVRKNTKSPVKFWFIENFLSPSFKAFLPHLAKEYGFEYELVTYKWPSWLRKQTEKQRII 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1247 WGYKILFLDVLFPLSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGFTPMCDSRTEMEGFRFWKQGYWANYLRGLPYHIS 1326
Cdd:pfam18404 81 WGYKILFLDVLFPLDLDKVIFVDADQVVRTDLKELVDMDLEGAPYGYTPMCDSRKEMEGFRFWKQGYWKDHLRGRPYHIS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1327 ALYVVDLNRFRQLAAGDRLRQQYHALSADPNSLSNLDQDLPNNMQFTIPIHSLPQEWLWCETWCSDESLAQARTIDLCNN 1406
Cdd:pfam18404 161 ALYVVDLKRFRQMAAGDRLRSHYQQLSADPNSLANLDQDLPNNMQHQVPIFSLPQEWLWCETWCSDESLKKAKTIDLCNN 240
|
250 260
....*....|....*....|....*...
gi 2124654928 1407 PQTKEPKLDRARRQVPEWTLYDEEIAAL 1434
Cdd:pfam18404 241 PLTKEPKLDRAKRIIPEWTDYDEEVAAL 268
|
|
| GT8_HUGT1_C_like |
cd06432 |
The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family; C-terminal domain ... |
1167-1414 |
0e+00 |
|
The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family; C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
Pssm-ID: 133054 Cd Length: 248 Bit Score: 549.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHLYERMLNIMMVSVMRNTKHTVKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREI 1246
Cdd:cd06432 1 INIFSVASGHLYERFLRIMMLSVMKNTKSPVKFWFIKNFLSPQFKEFLPEMAKEYGFEYELVTYKWPRWLHKQTEKQRII 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1247 WGYKILFLDVLFPLSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGFTPMCDSRTEMEGFRFWKQGYWANYLRGLPYHIS 1326
Cdd:cd06432 81 WGYKILFLDVLFPLNVDKVIFVDADQIVRTDLKELMDMDLKGAPYGYTPFCDSRKEMDGFRFWKQGYWKSHLRGRPYHIS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1327 ALYVVDLNRFRQLAAGDRLRQQYHALSADPNSLSNLDQDLPNNMQFTIPIHSLPQEWLWCETWCSDESLAQARTIDLCNN 1406
Cdd:cd06432 161 ALYVVDLKRFRRIAAGDRLRGQYQQLSQDPNSLANLDQDLPNNMQHQVPIFSLPQEWLWCETWCSDESKKKAKTIDLCNN 240
|
....*...
gi 2124654928 1407 PQTKEPKL 1414
Cdd:cd06432 241 PLTKEPKL 248
|
|
| Thioredoxin_14 |
pfam18402 |
Thioredoxin-like domain; This is the third out of four TRXL(thioredoxin-like) domains found in ... |
402-644 |
1.35e-89 |
|
Thioredoxin-like domain; This is the third out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
Pssm-ID: 465750 Cd Length: 248 Bit Score: 291.10 E-value: 1.35e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 402 FDWTDRLEEGKALLWLNDLEKDARYQKLPSDLTALLQRTYPGQLPQVALNLFHIVAPVDFTNIEDGR-AFGQLAQFMQRG 480
Cdd:pfam18402 1 FDIRDRIEGGGVIIWLNDLEKDKRYSRWPSSLQELLRPTYPGQLPPIRKNLFNLVLVVDLSQPEDLLlLVETLQSFVQRG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 481 VTLRFGILPLV-TTPASAAQAKVVYHLMETYGFESLITYLQESEE---GPEGAANKKAFTRAIDGRETLPgaNKMTLAEI 556
Cdd:pfam18402 81 IPVRFGLVPLVnSTEDGLAQAKLFYYLLENYGLKAALSFLTASLYalaKKVLSPTKAIFSSALKERTLRP--QALSFDEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 557 LEADTYKQRVEASKAWANRLNADTTVRPVFVNGLAIPREKSWVQAMGQRLTEDQQAIQKAVYFGQIEEGTPVSDLF--LR 634
Cdd:pfam18402 159 LKSEVYDERLKKAKEYLKRLGLDSLSGPVFVNGVPLPRDENWLQALSQRISEDLQLLQKAVYEGALTDDDDVPDFFydLP 238
|
250
....*....|
gi 2124654928 635 DAISKRNTYI 644
Cdd:pfam18402 239 NALPRRNPLI 248
|
|
| Thioredoxin_15 |
pfam18403 |
Thioredoxin-like domain; This is the fourth TRXL(thioredoxin-like) domain found in UDP-glucose: ... |
656-851 |
3.69e-64 |
|
Thioredoxin-like domain; This is the fourth TRXL(thioredoxin-like) domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
Pssm-ID: 465751 Cd Length: 205 Bit Score: 216.71 E-value: 3.69e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 656 DINKLHKDFVGLFGNIAVLPSDSkaPKESWAVLTAVADLATDDGQDLLLAALEFKRKNPGVRLDLVHNPPSSAEAH-VIN 734
Cdd:pfam18403 1 DLNKLYSEHADLFDKMPYLEASS--DKEDWATLWVVADLDSESGRKLLLSALEFRKSNPGVRLGIIHNPASPSEASsLIS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 735 GAFKLNEGKLAEMKNKDDLKAILEA----------SWTAEDDGLGTALADFLSASNILPGTKGLLLNGRVVGPLPSDVSF 804
Cdd:pfam18403 79 SALLAALLKLKNLDALEFLTKLLEEeeaaasesgkSSAEAAADYWKALQPFLRVLGLKPGQNALVLNGRVVGPIPEDEEF 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2124654928 805 NEDDLQQLLEFERRNRILPVYAAIKDLGFEDKLSDPIAAAKLTSITA 851
Cdd:pfam18403 159 SADDFELLLSYERSKRIEPVYKAIEELGLEDKISDPDAVAKLTSLVA 205
|
|
| Thioredoxin_12 |
pfam18400 |
Thioredoxin-like domain; This is one of four TRXL(thioredoxin-like) domains found in ... |
36-215 |
7.47e-61 |
|
Thioredoxin-like domain; This is one of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
Pssm-ID: 465748 Cd Length: 187 Bit Score: 206.32 E-value: 7.47e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 36 PYLLELLETAAGENSTAYFPLLDKIAG--GHFQSTNSDAELYDRFLEVLQQdgHITkPEALSTYKLALSLRVAAPRIEAH 113
Cdd:pfam18400 3 PLLLEALETLAEENPDLFFPFLDALTNldGEFADASTDEELYEAALKLASD--HLS-PLALSLFKLALSLRSASPRIEAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 114 YQYYTtavDSVSKGDTNDDCSTWALIDNKKYCS-ETLGKAVEGDFSAR-QVNLLPFDRVLGFGKD---AILYADPTSASF 188
Cdd:pfam18400 80 YQIYA---ESVSFEGAPPECDSWVDWGGEVYCDpEDLDALLKSEASSRpQPELLPFDHVYPDSGSspvAILYADLGSPNF 156
|
170 180
....*....|....*....|....*..
gi 2124654928 189 GPFHIALSKAAKQGDVSYRLRYRRSAG 215
Cdd:pfam18400 157 REFHKYLSELAKDGKIRYVLRHVPPSG 183
|
|
| UDP-g_GGTase |
pfam06427 |
UDP-glucose:Glycoprotein Glucosyltransferase; This domain consists of 7 stranded ... |
1021-1129 |
1.58e-60 |
|
UDP-glucose:Glycoprotein Glucosyltransferase; This domain consists of 7 stranded beta-sandwiches found in UDP-glucose-glycoprotein glucosyltransferase-like proteins. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.
Pssm-ID: 461910 Cd Length: 109 Bit Score: 202.33 E-value: 1.58e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1021 EGHSRDGKRGA-PRGAQLSLATEKEPLITDTIVMANLGYFQFKANPGFYNIQLKQGRTSKIFTIESVGAHGYaPVPGDEG 1099
Cdd:pfam06427 1 EGHARDVTTGSpPRGLQLVLGTEKNPHVADTIVMANLGYFQLKANPGVWKLELREGRSSDIYEIESVGAEGW-PSPGDEG 79
|
90 100 110
....*....|....*....|....*....|
gi 2124654928 1100 TEIALMDFKGTTLYPRLNRKPGMEEVDVLE 1129
Cdd:pfam06427 80 TEVALTSFEGLTLYPRLSRKPGMENEDVLE 109
|
|
| Thioredoxin_13 |
pfam18401 |
Thioredoxin-like domain; This is the second out of four TRXL(thioredoxin-like) domains found ... |
264-397 |
2.37e-56 |
|
Thioredoxin-like domain; This is the second out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
Pssm-ID: 465749 Cd Length: 136 Bit Score: 191.63 E-value: 2.37e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 264 EEVADLKPLSTSELASLGLKTASFILNSENPLDALVKSTQDFPKFSASIATHEVAKEFAAEQEKNVAAGIPSGINFLWMN 343
Cdd:pfam18401 1 EEVEDLKPLSVWELQDLGLQAAQFIMSSDDPLDTLLKLSQDFPKYASSLARHNVSDELREEIEENQERLLPPGDNALWLN 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2124654928 344 GVQLIERQIEPFTLIEMIRRERKLIDGVRDLGFNGQQANSLLGHSEVASSKAED 397
Cdd:pfam18401 81 GLQLDERDIDPFSLLDILRRERKLINGLRKLGLSGSEAVDLLSHPALAAAQADS 134
|
|
| RfaJ |
COG1442 |
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope ... |
1167-1383 |
1.07e-12 |
|
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441051 [Multi-domain] Cd Length: 301 Bit Score: 70.39 E-value: 1.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHlYERMLNIMMVSVMRNTKHT-VKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKwPHWLRQQKEKQR- 1244
Cdd:COG1442 6 INIVFAIDDN-YLPGLGVSIASLLENNPDRpYDFHILTDGLSDENKERLEALAAKYNVSIEFIDVD-DELLKDLPVSKHi 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1245 --EIWgYKiLFLDVLFPLSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGFTPMCDSRTEMEgfrfwkqgYWANYLrGLP 1322
Cdd:COG1442 84 skATY-YR-LLIPELLPDDYDKVLYLDADTLVLGDLSELWDIDLGGNLLAAVRDGTVTGSQK--------KRAKRL-GLP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1323 ----YHISALYVVDLNRFRQLAAGDRLRQqyhALSADPNSLSNLDQD-----LPNNmqftipIHSLPQEW 1383
Cdd:COG1442 153 dddgYFNSGVLLINLKKWREENITEKALE---FLKENPDKLKYPDQDilnivLGGK------VKFLPPRY 213
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Glyco_transf_24 |
pfam18404 |
Glucosyltransferase 24; This is the catalytic domain found in UDP-glucose:glycoprotein ... |
1167-1434 |
0e+00 |
|
Glucosyltransferase 24; This is the catalytic domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT). This domain belongs to glucosyltransferase 24 family (GT24) A-type domain. The GT domain displays the expected glycosyltransferase type A (GT-A) fold.
Pssm-ID: 436473 Cd Length: 268 Bit Score: 630.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHLYERMLNIMMVSVMRNTKHTVKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREI 1246
Cdd:pfam18404 1 INIFSVASGHLYERFLKIMMLSVRKNTKSPVKFWFIENFLSPSFKAFLPHLAKEYGFEYELVTYKWPSWLRKQTEKQRII 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1247 WGYKILFLDVLFPLSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGFTPMCDSRTEMEGFRFWKQGYWANYLRGLPYHIS 1326
Cdd:pfam18404 81 WGYKILFLDVLFPLDLDKVIFVDADQVVRTDLKELVDMDLEGAPYGYTPMCDSRKEMEGFRFWKQGYWKDHLRGRPYHIS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1327 ALYVVDLNRFRQLAAGDRLRQQYHALSADPNSLSNLDQDLPNNMQFTIPIHSLPQEWLWCETWCSDESLAQARTIDLCNN 1406
Cdd:pfam18404 161 ALYVVDLKRFRQMAAGDRLRSHYQQLSADPNSLANLDQDLPNNMQHQVPIFSLPQEWLWCETWCSDESLKKAKTIDLCNN 240
|
250 260
....*....|....*....|....*...
gi 2124654928 1407 PQTKEPKLDRARRQVPEWTLYDEEIAAL 1434
Cdd:pfam18404 241 PLTKEPKLDRAKRIIPEWTDYDEEVAAL 268
|
|
| GT8_HUGT1_C_like |
cd06432 |
The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family; C-terminal domain ... |
1167-1414 |
0e+00 |
|
The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family; C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
Pssm-ID: 133054 Cd Length: 248 Bit Score: 549.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHLYERMLNIMMVSVMRNTKHTVKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREI 1246
Cdd:cd06432 1 INIFSVASGHLYERFLRIMMLSVMKNTKSPVKFWFIKNFLSPQFKEFLPEMAKEYGFEYELVTYKWPRWLHKQTEKQRII 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1247 WGYKILFLDVLFPLSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGFTPMCDSRTEMEGFRFWKQGYWANYLRGLPYHIS 1326
Cdd:cd06432 81 WGYKILFLDVLFPLNVDKVIFVDADQIVRTDLKELMDMDLKGAPYGYTPFCDSRKEMDGFRFWKQGYWKSHLRGRPYHIS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1327 ALYVVDLNRFRQLAAGDRLRQQYHALSADPNSLSNLDQDLPNNMQFTIPIHSLPQEWLWCETWCSDESLAQARTIDLCNN 1406
Cdd:cd06432 161 ALYVVDLKRFRRIAAGDRLRGQYQQLSQDPNSLANLDQDLPNNMQHQVPIFSLPQEWLWCETWCSDESKKKAKTIDLCNN 240
|
....*...
gi 2124654928 1407 PQTKEPKL 1414
Cdd:cd06432 241 PLTKEPKL 248
|
|
| Thioredoxin_14 |
pfam18402 |
Thioredoxin-like domain; This is the third out of four TRXL(thioredoxin-like) domains found in ... |
402-644 |
1.35e-89 |
|
Thioredoxin-like domain; This is the third out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
Pssm-ID: 465750 Cd Length: 248 Bit Score: 291.10 E-value: 1.35e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 402 FDWTDRLEEGKALLWLNDLEKDARYQKLPSDLTALLQRTYPGQLPQVALNLFHIVAPVDFTNIEDGR-AFGQLAQFMQRG 480
Cdd:pfam18402 1 FDIRDRIEGGGVIIWLNDLEKDKRYSRWPSSLQELLRPTYPGQLPPIRKNLFNLVLVVDLSQPEDLLlLVETLQSFVQRG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 481 VTLRFGILPLV-TTPASAAQAKVVYHLMETYGFESLITYLQESEE---GPEGAANKKAFTRAIDGRETLPgaNKMTLAEI 556
Cdd:pfam18402 81 IPVRFGLVPLVnSTEDGLAQAKLFYYLLENYGLKAALSFLTASLYalaKKVLSPTKAIFSSALKERTLRP--QALSFDEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 557 LEADTYKQRVEASKAWANRLNADTTVRPVFVNGLAIPREKSWVQAMGQRLTEDQQAIQKAVYFGQIEEGTPVSDLF--LR 634
Cdd:pfam18402 159 LKSEVYDERLKKAKEYLKRLGLDSLSGPVFVNGVPLPRDENWLQALSQRISEDLQLLQKAVYEGALTDDDDVPDFFydLP 238
|
250
....*....|
gi 2124654928 635 DAISKRNTYI 644
Cdd:pfam18402 239 NALPRRNPLI 248
|
|
| Thioredoxin_15 |
pfam18403 |
Thioredoxin-like domain; This is the fourth TRXL(thioredoxin-like) domain found in UDP-glucose: ... |
656-851 |
3.69e-64 |
|
Thioredoxin-like domain; This is the fourth TRXL(thioredoxin-like) domain found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
Pssm-ID: 465751 Cd Length: 205 Bit Score: 216.71 E-value: 3.69e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 656 DINKLHKDFVGLFGNIAVLPSDSkaPKESWAVLTAVADLATDDGQDLLLAALEFKRKNPGVRLDLVHNPPSSAEAH-VIN 734
Cdd:pfam18403 1 DLNKLYSEHADLFDKMPYLEASS--DKEDWATLWVVADLDSESGRKLLLSALEFRKSNPGVRLGIIHNPASPSEASsLIS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 735 GAFKLNEGKLAEMKNKDDLKAILEA----------SWTAEDDGLGTALADFLSASNILPGTKGLLLNGRVVGPLPSDVSF 804
Cdd:pfam18403 79 SALLAALLKLKNLDALEFLTKLLEEeeaaasesgkSSAEAAADYWKALQPFLRVLGLKPGQNALVLNGRVVGPIPEDEEF 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2124654928 805 NEDDLQQLLEFERRNRILPVYAAIKDLGFEDKLSDPIAAAKLTSITA 851
Cdd:pfam18403 159 SADDFELLLSYERSKRIEPVYKAIEELGLEDKISDPDAVAKLTSLVA 205
|
|
| Thioredoxin_12 |
pfam18400 |
Thioredoxin-like domain; This is one of four TRXL(thioredoxin-like) domains found in ... |
36-215 |
7.47e-61 |
|
Thioredoxin-like domain; This is one of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
Pssm-ID: 465748 Cd Length: 187 Bit Score: 206.32 E-value: 7.47e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 36 PYLLELLETAAGENSTAYFPLLDKIAG--GHFQSTNSDAELYDRFLEVLQQdgHITkPEALSTYKLALSLRVAAPRIEAH 113
Cdd:pfam18400 3 PLLLEALETLAEENPDLFFPFLDALTNldGEFADASTDEELYEAALKLASD--HLS-PLALSLFKLALSLRSASPRIEAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 114 YQYYTtavDSVSKGDTNDDCSTWALIDNKKYCS-ETLGKAVEGDFSAR-QVNLLPFDRVLGFGKD---AILYADPTSASF 188
Cdd:pfam18400 80 YQIYA---ESVSFEGAPPECDSWVDWGGEVYCDpEDLDALLKSEASSRpQPELLPFDHVYPDSGSspvAILYADLGSPNF 156
|
170 180
....*....|....*....|....*..
gi 2124654928 189 GPFHIALSKAAKQGDVSYRLRYRRSAG 215
Cdd:pfam18400 157 REFHKYLSELAKDGKIRYVLRHVPPSG 183
|
|
| UDP-g_GGTase |
pfam06427 |
UDP-glucose:Glycoprotein Glucosyltransferase; This domain consists of 7 stranded ... |
1021-1129 |
1.58e-60 |
|
UDP-glucose:Glycoprotein Glucosyltransferase; This domain consists of 7 stranded beta-sandwiches found in UDP-glucose-glycoprotein glucosyltransferase-like proteins. UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.
Pssm-ID: 461910 Cd Length: 109 Bit Score: 202.33 E-value: 1.58e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1021 EGHSRDGKRGA-PRGAQLSLATEKEPLITDTIVMANLGYFQFKANPGFYNIQLKQGRTSKIFTIESVGAHGYaPVPGDEG 1099
Cdd:pfam06427 1 EGHARDVTTGSpPRGLQLVLGTEKNPHVADTIVMANLGYFQLKANPGVWKLELREGRSSDIYEIESVGAEGW-PSPGDEG 79
|
90 100 110
....*....|....*....|....*....|
gi 2124654928 1100 TEIALMDFKGTTLYPRLNRKPGMEEVDVLE 1129
Cdd:pfam06427 80 TEVALTSFEGLTLYPRLSRKPGMENEDVLE 109
|
|
| Glyco_transf_8 |
cd00505 |
Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis ... |
1167-1414 |
4.14e-59 |
|
Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis; Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+.
Pssm-ID: 132996 [Multi-domain] Cd Length: 246 Bit Score: 203.83 E-value: 4.14e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHLYERMLNIMMVSVMRNTKHTVKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKWPHWLRQQ-KEKQRE 1245
Cdd:cd00505 1 IAIVIVATGDEYLRGAIVLMKSVLRHRTKPLRFHVLTNPLSDTFKAALDNLRKLYNFNYELIPVDILDSVDSEhLKRPIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1246 IWGYKILFLDVLFPlSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGFTPMCDSRTEMEGFRFWKQGYWANYlrglpYHI 1325
Cdd:cd00505 81 IVTLTKLHLPNLVP-DYDKILYVDADILVLTDIDELWDTPLGGQELAAAPDPGDRREGKYYRQKRSHLAGPD-----YFN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1326 SALYVVDLNRFRQL-AAGDRLRQQYHALSadpnSLSNLDQDLPNNM--QFTIPIHSLPQEWLWCETWCSDESLAQ----- 1397
Cdd:cd00505 155 SGVFVVNLSKERRNqLLKVALEKWLQSLS----SLSGGDQDLLNTFfkQVPFIVKSLPCIWNVRLTGCYRSLNCFkafvk 230
|
250
....*....|....*...
gi 2124654928 1398 -ARTIDLCNNpqTKEPKL 1414
Cdd:cd00505 231 nAKVIHFNGP--TKPWNK 246
|
|
| Thioredoxin_13 |
pfam18401 |
Thioredoxin-like domain; This is the second out of four TRXL(thioredoxin-like) domains found ... |
264-397 |
2.37e-56 |
|
Thioredoxin-like domain; This is the second out of four TRXL(thioredoxin-like) domains found in UDP-glucose:glycoprotein glucosyltransferase (UGGT).
Pssm-ID: 465749 Cd Length: 136 Bit Score: 191.63 E-value: 2.37e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 264 EEVADLKPLSTSELASLGLKTASFILNSENPLDALVKSTQDFPKFSASIATHEVAKEFAAEQEKNVAAGIPSGINFLWMN 343
Cdd:pfam18401 1 EEVEDLKPLSVWELQDLGLQAAQFIMSSDDPLDTLLKLSQDFPKYASSLARHNVSDELREEIEENQERLLPPGDNALWLN 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2124654928 344 GVQLIERQIEPFTLIEMIRRERKLIDGVRDLGFNGQQANSLLGHSEVASSKAED 397
Cdd:pfam18401 81 GLQLDERDIDPFSLLDILRRERKLINGLRKLGLSGSEAVDLLSHPALAAAQADS 134
|
|
| RfaJ |
COG1442 |
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope ... |
1167-1383 |
1.07e-12 |
|
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441051 [Multi-domain] Cd Length: 301 Bit Score: 70.39 E-value: 1.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHlYERMLNIMMVSVMRNTKHT-VKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKwPHWLRQQKEKQR- 1244
Cdd:COG1442 6 INIVFAIDDN-YLPGLGVSIASLLENNPDRpYDFHILTDGLSDENKERLEALAAKYNVSIEFIDVD-DELLKDLPVSKHi 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1245 --EIWgYKiLFLDVLFPLSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGFTPMCDSRTEMEgfrfwkqgYWANYLrGLP 1322
Cdd:COG1442 84 skATY-YR-LLIPELLPDDYDKVLYLDADTLVLGDLSELWDIDLGGNLLAAVRDGTVTGSQK--------KRAKRL-GLP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1323 ----YHISALYVVDLNRFRQLAAGDRLRQqyhALSADPNSLSNLDQD-----LPNNmqftipIHSLPQEW 1383
Cdd:COG1442 153 dddgYFNSGVLLINLKKWREENITEKALE---FLKENPDKLKYPDQDilnivLGGK------VKFLPPRY 213
|
|
| GT8_A4GalT_like |
cd04194 |
A4GalT_like proteins catalyze the addition of galactose or glucose residues to the ... |
1167-1383 |
2.17e-08 |
|
A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.
Pssm-ID: 133037 [Multi-domain] Cd Length: 248 Bit Score: 56.84 E-value: 2.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1167 INIFSVASGHlYERMLNIMMVSVMRNTKHT-VKFWFIEQFLSPSFKEFIPHMAAEYGFKYEMVTYKwphwLRQQKEKQRE 1245
Cdd:cd04194 1 MNIVFAIDDN-YAPYLAVTIKSILANNSKRdYDFYILNDDISEENKKKLKELLKKYNSSIEFIKID----NDDFKFFPAT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124654928 1246 IWGYKI-----LFLDVLFPlSLDKVIFVDADQIVRTDMIDLVNHDLEGAPYGftpMCdsrTEMEGFRFWKQGYWANYLRG 1320
Cdd:cd04194 76 TDHISYatyyrLLIPDLLP-DYDKVLYLDADIIVLGDLSELFDIDLGDNLLA---AV---RDPFIEQEKKRKRRLGGYDD 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2124654928 1321 LPYHISALYVVDLNRFRQLAAGDRLRQqyhALSADPNSLSNLDQD-LpnNMQFTIPIHSLPQEW 1383
Cdd:cd04194 149 GSYFNSGVLLINLKKWREENITEKLLE---LIKEYGGRLIYPDQDiL--NAVLKDKILYLPPRY 207
|
|
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