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Conserved domains on  [gi|2123875648|ref|XP_044400183|]
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ubiquinone biosynthesis monooxygenase COQ6, mitochondrial-like isoform X1 [Triticum aestivum]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 63-511 0e+00

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01989:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 437  Bit Score: 630.64  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  63 LDVAIVGGGMVGLAVACALSNMPLTKHLRVAVIDS--NPALKSTNYLKKDGIPDSRVSTVTPATISFFRDIGAWEHILQQ 140
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAvdNPKLKSRNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 141 RHAFFGKMQVWDYTGLGYTRYNASDVcKEYLGCVVENKVLCNSLLLRLQEQKEDIEKMVYPTRLVSLAFPSKSRNvgvag 220
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNG-KEDMACIIENDNIQNSLYNRLQEYNGDNVKILNPARLISVTIPSKYPN----- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 221 lkppsteaeelRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHT--AENDTAWQRFL 298
Cdd:TIGR01989 155 -----------DNSNWVHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEeaTENDVAWQRFL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 299 PSGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRALDFGYGPHPNSSSLDHYVERLFSDFGGTAASTKECF 378
Cdd:TIGR01989 224 PTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCF 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 379 EVPPRAIGLISE-RMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLL 457
Cdd:TIGR01989 304 QVPPRVIGVVDKsRAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSL 383

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2123875648 458 NRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNII 511
Cdd:TIGR01989 384 KPYERERYAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 63-511 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 630.64  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  63 LDVAIVGGGMVGLAVACALSNMPLTKHLRVAVIDS--NPALKSTNYLKKDGIPDSRVSTVTPATISFFRDIGAWEHILQQ 140
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAvdNPKLKSRNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 141 RHAFFGKMQVWDYTGLGYTRYNASDVcKEYLGCVVENKVLCNSLLLRLQEQKEDIEKMVYPTRLVSLAFPSKSRNvgvag 220
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNG-KEDMACIIENDNIQNSLYNRLQEYNGDNVKILNPARLISVTIPSKYPN----- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 221 lkppsteaeelRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHT--AENDTAWQRFL 298
Cdd:TIGR01989 155 -----------DNSNWVHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEeaTENDVAWQRFL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 299 PSGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRALDFGYGPHPNSSSLDHYVERLFSDFGGTAASTKECF 378
Cdd:TIGR01989 224 PTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCF 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 379 EVPPRAIGLISE-RMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLL 457
Cdd:TIGR01989 304 QVPPRVIGVVDKsRAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSL 383

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2123875648 458 NRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNII 511
Cdd:TIGR01989 384 KPYERERYAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
PRK07364 PRK07364
FAD-dependent hydroxylase;
60-511 6.08e-90

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 281.91  E-value: 6.08e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  60 DDELDVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPALKStnyLKKDgipdsRVSTVTPATISFFRDIGAWEHILQ 139
Cdd:PRK07364   16 SLTYDVAIVGGGIVGLTLAAALKD----SGLRIALIEAQPAEAA---AAKG-----QAYALSLLSARIFEGIGVWEKILP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 140 QRhAFFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLcnslLLRLQEQKEDIEKMVY--PTRLVSLAFPSKSRNVg 217
Cdd:PRK07364   84 QI-GKFRQIRLSDADYPGVVKFQPTDLGTEALGYVGEHQVL----LEALQEFLQSCPNITWlcPAEVVSVEYQQDAATV- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 218 vaglkppsteaeELRRSNLVkldlsdgQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHTA-ENDTAWQR 296
Cdd:PRK07364  158 ------------TLEIEGKQ-------QTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEApHNDIAYER 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 297 FLPSGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVmsvnraldfgygphpnsssldHYVERLFSDFGGTaastke 376
Cdd:PRK07364  219 FWPSGPFAILPLPGNRCQIVWTAPHAQAKALLALPEAEFL---------------------AELQQRYGDQLGK------ 271

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 377 cfevppraIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSL 456
Cdd:PRK07364  272 --------LELLGDRFLFPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAV 343

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2123875648 457 LNRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNII 511
Cdd:PRK07364  344 LKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLKRLAL 398
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 64-507 2.53e-57

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 194.00  E-value: 2.53e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPALKstnylkkdgiPDSRVSTVTPATISFFRDIGAWEHILQQRHA 143
Cdd:COG0654     5 DVLIVGGGPAGLALALALAR----AGIRVTVVERAPPPR----------PDGRGIALSPRSLELLRRLGLWDRLLARGAP 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 144 FFGkMQVWD-YTGLGYTRYNASDVCKEYlGCVVENKVLCNSLLLRLQEQKEDIekmVYPTRLVSLAfpsksrnvgvaglk 222
Cdd:COG0654    71 IRG-IRVRDgSDGRVLARFDAAETGLPA-GLVVPRADLERALLEAARALGVEL---RFGTEVTGLE-------------- 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 223 ppsteaeelRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEhtaendtawqrflpsgp 302
Cdd:COG0654   132 ---------QDADGVTVTLADGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR----------------- 185

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 303 iallpigdnfsnivwtmspeeasrhksmssedfvmsvnraldfgygphpnsssldHYVERLFSDFGGtaastkecfevPP 382
Cdd:COG0654   186 -------------------------------------------------------TELRARLAAAGP-----------RL 199

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 383 RAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEgvsVGADIGDLSLLNRYEN 462
Cdd:COG0654   200 GELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAA---ALRGRDDEAALARYER 276

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 2123875648 463 DRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLK 507
Cdd:COG0654   277 ERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 62-474 7.47e-14

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 72.74  E-value: 7.47e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  62 ELDVAIVGGGMVGLAVACALSnmplTKHLRVAVIDSNPALkstnylkkdgIPDSRVSTVTPATISFFRDIGAWEHILQQ- 140
Cdd:pfam01494   1 ETDVLIVGGGPAGLMLALLLA----RAGVRVVLVERHATT----------SVLPRAHGLNQRTMELLRQAGLEDRILAEg 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 141 -RHAFFGKMQvwdYTGLGYTRYNASDVCKEYLGCVvENKVLcNSLLLRLQEQKEDIEkmvYPTRLVSLafpsksrnvgva 219
Cdd:pfam01494  67 vPHEGMGLAF---YNTRRRADLDFLTSPPRVTVYP-QTELE-PILVEHAEARGAQVR---FGTEVLSL------------ 126

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 220 gLKPPSTEAEELRrsnlvklDLSDG--QTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICT------VEHTAEND 291
Cdd:pfam01494 127 -EQDGDGVTAVVR-------DRRDGeeYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVlfdapdLSDPVERA 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 292 T--AWQRFLPSGPIALLPIGDNFSN---IVWTMSPEEASRhksmsSEDFvmsvnraldfgygphpnssSLDHYVERLFSD 366
Cdd:pfam01494 199 FvhYLIYAPHSRGFMVGPWRSAGREryyVQVPWDEEVEER-----PEEF-------------------TDEELKQRLRSI 254

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 367 FGgtaastkecfevPPRAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEgvs 446
Cdd:pfam01494 255 VG------------IDLALVEILWKSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLAA--- 319

                         410       420
                  ....*....|....*....|....*...
gi 2123875648 447 VGADIGDLSLLNRYENDRkgANVAMAAV 474
Cdd:pfam01494 320 VLRGQAGESLLDTYSAER--LPVAWAVV 345
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 63-511 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 630.64  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  63 LDVAIVGGGMVGLAVACALSNMPLTKHLRVAVIDS--NPALKSTNYLKKDGIPDSRVSTVTPATISFFRDIGAWEHILQQ 140
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAvdNPKLKSRNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 141 RHAFFGKMQVWDYTGLGYTRYNASDVcKEYLGCVVENKVLCNSLLLRLQEQKEDIEKMVYPTRLVSLAFPSKSRNvgvag 220
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDNG-KEDMACIIENDNIQNSLYNRLQEYNGDNVKILNPARLISVTIPSKYPN----- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 221 lkppsteaeelRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHT--AENDTAWQRFL 298
Cdd:TIGR01989 155 -----------DNSNWVHITLSDGQVLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEeaTENDVAWQRFL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 299 PSGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRALDFGYGPHPNSSSLDHYVERLFSDFGGTAASTKECF 378
Cdd:TIGR01989 224 PTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCF 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 379 EVPPRAIGLISE-RMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLL 457
Cdd:TIGR01989 304 QVPPRVIGVVDKsRAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSL 383

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2123875648 458 NRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNII 511
Cdd:TIGR01989 384 KPYERERYAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 64-516 2.35e-161

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 463.21  E-value: 2.35e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNMPLtkhlRVAVIDSNPALKStnylkKDGIPDSRVSTVTPATISFFRDIGAWEHILQQRHA 143
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARSGL----KVALIEATPLPAP-----ADPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQ 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 144 FFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQKEdiekmvyptrlVSLAFPsksrnvgvaglkp 223
Cdd:TIGR01988  72 PIRDIHVSDGGSFGALRFDADEIGLEALGYVVENRVLQQALWERLQELPN-----------VTLLCP------------- 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 224 psTEAEELRR-SNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEH-TAENDTAWQRFLPSG 301
Cdd:TIGR01988 128 --ARVVELPRhSDHVELTLDDGQQLRARLLVGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHeRPHQGTAWERFTPTG 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 302 PIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRALDFGYGphpnsssldhyverlfsdfggtaastkecfevp 381
Cdd:TIGR01988 206 PLALLPLPDNRSSLVWTLPPEEAERLLALSDEEFLAELQRAFGSRLG--------------------------------- 252

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 382 prAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLLNRYE 461
Cdd:TIGR01988 253 --AITLVGERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYE 330

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2123875648 462 NDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:TIGR01988 331 RRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
PRK07364 PRK07364
FAD-dependent hydroxylase;
60-511 6.08e-90

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 281.91  E-value: 6.08e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  60 DDELDVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPALKStnyLKKDgipdsRVSTVTPATISFFRDIGAWEHILQ 139
Cdd:PRK07364   16 SLTYDVAIVGGGIVGLTLAAALKD----SGLRIALIEAQPAEAA---AAKG-----QAYALSLLSARIFEGIGVWEKILP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 140 QRhAFFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLcnslLLRLQEQKEDIEKMVY--PTRLVSLAFPSKSRNVg 217
Cdd:PRK07364   84 QI-GKFRQIRLSDADYPGVVKFQPTDLGTEALGYVGEHQVL----LEALQEFLQSCPNITWlcPAEVVSVEYQQDAATV- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 218 vaglkppsteaeELRRSNLVkldlsdgQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHTA-ENDTAWQR 296
Cdd:PRK07364  158 ------------TLEIEGKQ-------QTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEApHNDIAYER 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 297 FLPSGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVmsvnraldfgygphpnsssldHYVERLFSDFGGTaastke 376
Cdd:PRK07364  219 FWPSGPFAILPLPGNRCQIVWTAPHAQAKALLALPEAEFL---------------------AELQQRYGDQLGK------ 271

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 377 cfevppraIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSL 456
Cdd:PRK07364  272 --------LELLGDRFLFPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAV 343

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2123875648 457 LNRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNII 511
Cdd:PRK07364  344 LKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLKRLAL 398
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 63-516 1.51e-87

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 275.11  E-value: 1.51e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  63 LDVAIVGGGMVGLAVACALSNmpltKHLRVAVIDS---NPALKStnylkkdgIPDSRVSTVTPATISFFRDIGAWEHILQ 139
Cdd:PRK08850    5 VDVAIIGGGMVGLALAAALKE----SDLRIAVIEGqlpEEALNE--------LPDVRVSALSRSSEHILRNLGAWQGIEA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 140 QRHAFFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQkeDIEKMVYPTRLVSLAFpsksrnvgva 219
Cdd:PRK08850   73 RRAAPYIAMEVWEQDSFARIEFDAESMAQPDLGHIVENRVIQLALLEQVQKQ--DNVTLLMPARCQSIAV---------- 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 220 glkppsTEAEELrrsnlvkLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEhTAE--NDTAWQRF 297
Cdd:PRK08850  141 ------GESEAW-------LTLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVANVR-TVDphNSVARQIF 206

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 298 LPSGPIALLPIGD-NFSNIVWTMSPEEASRHKSMSSEDFvmsvNRALdfgygphpnsssldhyverlfsdfggTAAstke 376
Cdd:PRK08850  207 TPQGPLAFLPMSEpNMSSIVWSTEPLRAEALLAMSDEQF----NKAL--------------------------TAE---- 252

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 377 cFEVPPRAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSL 456
Cdd:PRK08850  253 -FDNRLGLCEVVGERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEILALWQQGRDIGLKRN 331

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 457 LNRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:PRK08850  332 LRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRALG 391
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 64-516 8.84e-82

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 259.92  E-value: 8.84e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVID-SNPALkstnyLKKDGIPDSRVSTVTPATISFFRDIGAWEHILQQRH 142
Cdd:PRK08020    7 DIAIVGGGMVGAALALGLAQ----HGFSVAVLEhAAPAP-----FDADSQPDVRISAISAASVALLKGLGVWDAVQAMRS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 143 AFFGKMQVWDYTGlGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQkEDIEKMVyPTRLVSLAfpsksrnvgvaglk 222
Cdd:PRK08020   78 HPYRRLETWEWET-AHVVFDAAELKLPELGYMVENRVLQLALWQALEAH-PNVTLRC-PASLQALQ-------------- 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 223 ppsteaeelRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVE-HTAENDTAWQRFLPSG 301
Cdd:PRK08020  141 ---------RDDDGWELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVKcENPPGDSTWQQFTPSG 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 302 PIALLPIGDNFSNIVWTMSPEEASRHKSMSSEdfvmSVNRALdfgygphpnsssLDHYVERLfsdfgGTaastkecfeVP 381
Cdd:PRK08020  212 PRAFLPLFDNWASLVWYDSPARIRQLQAMSMA----QLQQEI------------AAHFPARL-----GA---------VT 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 382 PRAIGlisermAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLLNRYE 461
Cdd:PRK08020  262 PVAAG------AFPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAWASEAVLKRYQ 335

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2123875648 462 NDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:PRK08020  336 RRRMADNLLMQSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYALG 390
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 64-516 2.82e-79

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 253.98  E-value: 2.82e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPAlkSTNYLKKDGIPDSRVSTVTPATISFFRDIGAWEHILQQRHA 143
Cdd:PRK05714    4 DLLIVGAGMVGSALALALQG----SGLEVLLLDGGPL--SVKPFDPQAPFEPRVSALSAASQRILERLGAWDGIAARRAS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 144 FFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQkediekmvyptrlvslafpsksrNVGVAglkp 223
Cdd:PRK05714   78 PYSEMQVWDGSGTGQIHFSAASVHAEVLGHIVENRVVQDALLERLHDS-----------------------DIGLL---- 130

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 224 PSTEAEELRRS-NLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHT-AENDTAWQRFLPSG 301
Cdd:PRK05714  131 ANARLEQMRRSgDDWLLTLADGRQLRAPLVVAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSePHRATAWQRFTDDG 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 302 PIALLPI----GDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRALDFGYGphpnsssldhyverlfsdfggtaastkEC 377
Cdd:PRK05714  211 PLAFLPLerdgDEHWCSIVWSTTPEEAERLMALDDDAFCAALERAFEGRLG---------------------------EV 263

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 378 FEVPPRaigliserMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLL 457
Cdd:PRK05714  264 LSADPR--------LCVPLRQRHAKRYVEPGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVL 335

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2123875648 458 NRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:PRK05714  336 SRFERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKLVDQMPEAKALFVRQALG 394
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 64-516 2.36e-76

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 245.30  E-value: 2.36e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpLTKhLRVAVIDSN--PALKSTNylkkdgipDSRVSTVTPATISFFRDIGAWEHiLQQR 141
Cdd:TIGR01984   1 DVIIVGGGLVGLSLALALSR--LGK-IKIALIEANspSAAQPGF--------DARSLALSYGSKQILEKLGLWPK-LAPF 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 142 HAFFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQKediekmvyptrlvslafpsksrnvgVAGL 221
Cdd:TIGR01984  69 ATPILDIHVSDQGHFGATHLRASEFGLPALGYVVELADLGQALLSRLALLT-------------------------NIQL 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 222 KPPSTEAEELRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHTA-ENDTAWQRFLPS 300
Cdd:TIGR01984 124 YCPARYKEIIRNQDYVRVTLDNGQQLRAKLLIAADGANSKVRELLSIPTEEHDYNQTALIANIRHEQpHQGCAFERFTPH 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 301 GPIALLPIGDNF-SNIVWTMSPEEASRHKSMSSEDFVMSVNRAldFGYgphpnsssldhyverlfsDFGgtaastkecfe 379
Cdd:TIGR01984 204 GPLALLPLKDNYrSSLVWCLPSKQADTIANLPDAEFLAELQQA--FGW------------------RLG----------- 252

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 380 vpprAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSvgaDIGDLSLLNR 459
Cdd:TIGR01984 253 ----KITQVGERKTYPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVLIDARI---DLGTYALLQE 325

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2123875648 460 YENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:TIGR01984 326 YLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPPLKKRLARQAMG 382
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
63-516 2.24e-75

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 243.73  E-value: 2.24e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  63 LDVAIVGGGMVGLAVACALSNMplTKHLRVAVIDSNPALKSTNylkkdgipDSRVSTVTPATISFFRDIGAWEHILQQRH 142
Cdd:PRK07333    2 CDVVIAGGGYVGLALAVALKQA--APHLPVTVVDAAPAGAWSR--------DPRASAIAAAARRMLEALGVWDEIAPEAQ 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 143 AFFgKMQVWDytglGYTrynaSDVCK-------------EYLGCVVENKVLCNSLLLRLQEqkEDIEkMVYPTRLVSlaF 209
Cdd:PRK07333   72 PIT-DMVITD----SRT----SDPVRpvfltfegevepgEPFAHMVENRVLINALRKRAEA--LGID-LREATSVTD--F 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 210 PSKSRNVGVAglkppsteaeelrrsnlvkldLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHT-A 288
Cdd:PRK07333  138 ETRDEGVTVT---------------------LSDGSVLEARLLVAADGARSKLRELAGIKTVGWDYGQSGIVCTVEHErP 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 289 ENDTAWQRFLPSGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRAldFGygphpnsssldHYVERLfsdfg 368
Cdd:PRK07333  197 HGGRAEEHFLPAGPFAILPLKGNRSSLVWTERTADAERLVALDDLVFEAELEQR--FG-----------HRLGEL----- 258

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 369 gtaastkecfevppRAIGlisERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVG 448
Cdd:PRK07333  259 --------------KVLG---KRRAFPLGLTLARSFVAPRFALVGDAAHGIHPIAGQGLNLGLKDVAALAEVVVEAARLG 321

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2123875648 449 ADIGDLSLLNRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:PRK07333  322 LDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVDRLPKLKSFFIRQAAG 389
PRK08013 PRK08013
oxidoreductase; Provisional
 64-516 2.94e-75

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 243.03  E-value: 2.94e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPALKstnyLKKDGIPDSRVSTVTPATISFFRDIGAWEHILQQRHA 143
Cdd:PRK08013    5 DVVIAGGGMVGLAVACGLQG----SGLRVAVLEQRVPEP----LAADAPPALRVSAINAASEKLLTRLGVWQDILARRAS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 144 FFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQKEdiekmvyptrlVSLAFPSKSRNVGVAglkp 223
Cdd:PRK08013   77 CYHGMEVWDKDSFGRIAFDDQSMGYSHLGHIIENSVIHYALWQKAQQSSD-----------ITLLAPAELQQVAWG---- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 224 psteaeelrrSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEhTAE--NDTAWQRFLPSG 301
Cdd:PRK08013  142 ----------ENEAFLTLKDGSMLTARLVVGADGANSWLRNKADIPLTFWDYQHHALVATIR-TEEphDAVARQVFHGDG 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 302 PIALLPIGD-NFSNIVWTMSPEEASRHKSMSSEDFvmsvNRALdfgygphpnSSSLDHyveRLfsdfggtaastKECfev 380
Cdd:PRK08013  211 ILAFLPLSDpHLCSIVWSLSPEEAQRMQQAPEEEF----NRAL---------AIAFDN---RL-----------GLC--- 260

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 381 ppraiGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLLNRY 460
Cdd:PRK08013  261 -----ELESERQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHRQGKDIGQHLYLRRY 335

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2123875648 461 ENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:PRK08013  336 ERSRKHSAALMLAGMQGFRDLFAGNNPAKKLLRDIGLKLADTLPGVKPQLIRQAMG 391
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
64-516 2.12e-72

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 235.23  E-value: 2.12e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPALkstnyLKKDGIPDSRVSTVTPATISFFRDIGAWEHILQQRHA 143
Cdd:PRK07608    7 DVVVVGGGLVGASLALALAQ----SGLRVALLAPRAPP-----RPADDAWDSRVYAISPSSQAFLERLGVWQALDAARLA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 144 FFGKMQVWDYTGlGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQkEDIEkmVYPTRLVSLAFpsksrnvgvaglkp 223
Cdd:PRK07608   78 PVYDMRVFGDAH-ARLHFSAYQAGVPQLAWIVESSLIERALWAALRFQ-PNLT--WFPARAQGLEV-------------- 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 224 psteaeelrRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAII----CTVEHtaeNDTAWQRFLP 299
Cdd:PRK07608  140 ---------DPDAATLTLADGQVLRADLVVGADGAHSWVRSQAGIKAERRPYRQTGVVanfkAERPH---RGTAYQWFRD 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 300 SGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRALDFGYGphpnsssldhyverlfsdfggtaastkecfe 379
Cdd:PRK07608  208 DGILALLPLPDGHVSMVWSARTAHADELLALSPEALAARVERASGGRLG------------------------------- 256

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 380 vpprAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVgADIGDLSLLNR 459
Cdd:PRK07608  257 ----RLECVTPAAGFPLRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAGREPF-RDLGDLRLLRR 331

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2123875648 460 YENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAA--AFHGAQyiSPLKKNIISYAMG 516
Cdd:PRK07608  332 YERARREDILALQVATDGLQRLFALPGPLARWLRNAgmALVGAL--PLVKRWLVRHALG 388
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 61-516 5.23e-69

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 226.58  E-value: 5.23e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  61 DELDVAIVGGGMVGLAVACALSNMPLTkhlrVAVIDSnpalKSTNYLKKDGIPDSRVSTVTPATISFFRDIGAWEHILQQ 140
Cdd:PRK08849    2 NKYDIAVVGGGMVGAATALGFAKQGRS----VAVIEG----GEPKAFEPSQPMDIRVSAISQTSVDLLESLGAWSSIVAM 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 141 RHAFFGKMQVWDYTGLgYTRYNASDVCKEYLGCVVENKVLcnSLLLRLQEQKEDIEKMVYPTRLVSLAFPSKSrnvgvag 220
Cdd:PRK08849   74 RVCPYKRLETWEHPEC-RTRFHSDELNLDQLGYIVENRLI--QLGLWQQFAQYPNLTLMCPEKLADLEFSAEG------- 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 221 lkppsteaeelrrsNLVKLDlsDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVE-HTAENDTAWQRFLP 299
Cdd:PRK08849  144 --------------NRVTLE--SGAEIEAKWVIGADGANSQVRQLAGIGITAWDYRQHCMLINVEtEQPQQDITWQQFTP 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 300 SGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEdfvmsvnraldfgygphpnssSLDHYVERLFsdfggtaastkecfe 379
Cdd:PRK08849  208 SGPRSFLPLCGNQGSLVWYDSPKRIKQLSAMNPE---------------------QLRSEILRHF--------------- 251

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 380 vpPRAIGLIS--ERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEgvsvgADIGDLSLL 457
Cdd:PRK08849  252 --PAELGEIKvlQHGSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVLLAETEK-----QGVLNDASF 324

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2123875648 458 NRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:PRK08849  325 ARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKTQVLKYALG 383
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
63-506 1.33e-65

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 217.81  E-value: 1.33e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  63 LDVAIVGGGMVGLAVACALSNMPLTkhlrVAVIDS-NPALKSTNYlkkdgiPDSRVSTVTPATISFFRDIGAWEHILQQR 141
Cdd:PRK08773    7 RDAVIVGGGVVGAACALALADAGLS----VALVEGrEPPRWQADQ------PDLRVYAFAADNAALLDRLGVWPAVRAAR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 142 HAFFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLqeqkediekmvyPTRLVSLAFPSKsrnvgVAGL 221
Cdd:PRK08773   77 AQPYRRMRVWDAGGGGELGFDADTLGREQLGWIVENDLLVDRLWAAL------------HAAGVQLHCPAR-----VVAL 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 222 KPPSTEaeelrrsnlVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVE-HTAENDTAWQRFLPS 300
Cdd:PRK08773  140 EQDADR---------VRLRLDDGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAFVDtEHPHQATAWQRFLPT 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 301 GPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRAldfgygphpnsssldhyverlfsdFGGTAASTKecfev 380
Cdd:PRK08773  211 GPLALLPFADGRSSIVWTLPDAEAERVLALDEAAFSRELTQA------------------------FAARLGEVR----- 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 381 ppraigLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLLNRY 460
Cdd:PRK08773  262 ------VASPRTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARRADWAAPHRLQRW 335

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2123875648 461 ENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPL 506
Cdd:PRK08773  336 ARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLPPL 381
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 64-516 1.02e-62

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 210.10  E-value: 1.02e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSnmPLTKH-LRVAVIDSN-PALkstnylkkDGIP--DSRVSTVTPATISFFRDIGAWEHI-- 137
Cdd:PRK05732    5 DVIIVGGGMAGATLALALS--RLSHGgLPVALIEAFaPES--------DAHPgfDARAIALAAGTCQQLARLGVWQALad 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 138 ----LQQRHaffgkmqVWDYTGLGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEqkediekmvypTRLVSLAFPSKs 213
Cdd:PRK05732   75 catpITHIH-------VSDRGHAGFVRLDAEDYGVPALGYVVELHDVGQRLFALLDK-----------APGVTLHCPAR- 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 214 rnvgVAGLKppsteaeelRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEhTAE--ND 291
Cdd:PRK05732  136 ----VANVE---------RTQGSVRVTLDDGETLTGRLLVAADGSHSALREALGIDWQQHPYEQVAVIANVT-TSEahQG 201

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 292 TAWQRFLPSGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNRAldFGYgphpnsssldhyveRLfsdfgGTA 371
Cdd:PRK05732  202 RAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSWSDAQFLAELQQA--FGW--------------RL-----GRI 260

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 372 astkecfevppRAIGlisERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADI 451
Cdd:PRK05732  261 -----------THAG---KRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEDI 326

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2123875648 452 GDLSLLNRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMG 516
Cdd:PRK05732  327 GDYAVLQRYQQRRQQDREATIGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLPPARDWLARRTLG 391
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 64-507 2.53e-57

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 194.00  E-value: 2.53e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPALKstnylkkdgiPDSRVSTVTPATISFFRDIGAWEHILQQRHA 143
Cdd:COG0654     5 DVLIVGGGPAGLALALALAR----AGIRVTVVERAPPPR----------PDGRGIALSPRSLELLRRLGLWDRLLARGAP 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 144 FFGkMQVWD-YTGLGYTRYNASDVCKEYlGCVVENKVLCNSLLLRLQEQKEDIekmVYPTRLVSLAfpsksrnvgvaglk 222
Cdd:COG0654    71 IRG-IRVRDgSDGRVLARFDAAETGLPA-GLVVPRADLERALLEAARALGVEL---RFGTEVTGLE-------------- 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 223 ppsteaeelRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEhtaendtawqrflpsgp 302
Cdd:COG0654   132 ---------QDADGVTVTLADGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVR----------------- 185

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 303 iallpigdnfsnivwtmspeeasrhksmssedfvmsvnraldfgygphpnsssldHYVERLFSDFGGtaastkecfevPP 382
Cdd:COG0654   186 -------------------------------------------------------TELRARLAAAGP-----------RL 199

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 383 RAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEgvsVGADIGDLSLLNRYEN 462
Cdd:COG0654   200 GELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLAA---ALRGRDDEAALARYER 276

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 2123875648 463 DRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLK 507
Cdd:COG0654   277 ERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLK 321
PRK09126 PRK09126
FAD-dependent hydroxylase;
64-519 5.92e-49

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 173.59  E-value: 5.92e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNP--ALKSTNYlkkdgipDSRVSTVTPATISFFRDIGAWEHILQQR 141
Cdd:PRK09126    5 DIVVVGAGPAGLSFARSLAG----SGLKVTLIERQPlaALADPAF-------DGREIALTHASREILQRLGAWDRIPEDE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 142 HAFFGKMQVWDYTGLGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQKEdiekmvypTRLVSlafpsksrNVGVAGL 221
Cdd:PRK09126   74 ISPLRDAKVLNGRSPFALTFDARGRGADALGYLVPNHLIRRAAYEAVSQQDG--------IELLT--------GTRVTAV 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 222 KPPSTEAEelrrsnlvkLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHT-AENDTAWQRFLPS 300
Cdd:PRK09126  138 RTDDDGAQ---------VTLANGRRLTARLLVAADSRFSATRRQLGIGADMHDFGRTMLVCRMRHElPHHHTAWEWFGYG 208

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 301 GPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFvmsvnraldfgygphpnsssldhyverlfsdfggtAASTKECFEV 380
Cdd:PRK09126  209 QTLALLPLNGHLSSLVLTLPPDQIEALLALDPEAF-----------------------------------AAEVTARFKG 253

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 381 PPRAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGDLSLLNRY 460
Cdd:PRK09126  254 RLGAMRLVSSRHAYPLVAVYAHRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAASLLERY 333

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2123875648 461 ENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMGDRK 519
Cdd:PRK09126  334 ERKHRLATRPLYHATNAIAALYTDDRPPARLLRRAVLRAANRFPPLKQAIAKQLTGRKK 392
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
64-508 7.00e-48

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 170.47  E-value: 7.00e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSnmplTKHLRVAVIDSNPAlkstnylkkdgIPDSRVSTVTPATISFFRDIGAWEHiLQQRHA 143
Cdd:PRK07494    9 DIAVIGGGPAGLAAAIALA----RAGASVALVAPEPP-----------YADLRTTALLGPSIRFLERLGLWAR-LAPHAA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 144 FFGKMQVWDYTG----LGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEqkediekmvyptrlvslafpsksrnvgVA 219
Cdd:PRK07494   73 PLQSMRIVDATGrlirAPEVRFRAAEIGEDAFGYNIPNWLLNRALEARVAE---------------------------LP 125

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 220 GLKPPSTEAEELR-RSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHTAEND---TAWQ 295
Cdd:PRK07494  126 NITRFGDEAESVRpREDEVTVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVLNFTHSRPHQnvsTEFH 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 296 RflPSGPIALLPIGDNFSNIVWTMSPEEASRHKSMSSEDFVMSVNraldfgygphpnsssldhyvERLFSDFGgtaastk 375
Cdd:PRK07494  206 T--EGGPFTQVPLPGRRSSLVWVVRPAEAERLLALSDAALSAAIE--------------------ERMQSMLG------- 256

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 376 ecfevpprAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEgvsVGADIGDLS 455
Cdd:PRK07494  257 --------KLTLEPGRQAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLVEIVED---RPEDPGSAA 325

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2123875648 456 LLNRYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKK 508
Cdd:PRK07494  326 VLAAYDRARRPDILSRTASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRR 378
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
64-515 4.15e-41

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 152.53  E-value: 4.15e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNMPLTKHLRVAVIDSNPALKSTNylkkdgipDSRVSTVTPATISFFRDIGAW-------EH 136
Cdd:PRK06996   13 DIAIVGAGPVGLALAGWLARRSATRALSIALIDAREPAASAN--------DPRAIALSHGSRVLLETLGAWpadatpiEH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 137 I-LQQRHAFfgkmqvwdytglGYTRYNASDVCKEYLGCVVENKVLCNSLLLRLQEQKEDiekmvYPTRLVSLAfpsksrn 215
Cdd:PRK06996   85 IhVSQRGHF------------GRTLIDRDDHDVPALGYVVRYGSLVAALARAVRGTPVR-----WLTSTTAHA------- 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 216 vgvaglkpPSTEAEELrrsnLVKLDLSDGQ-TLYSKLVVGADGSK-SNVRQIAGIKTTGWSYPQSAIICTVEHTA-ENDT 292
Cdd:PRK06996  141 --------PAQDADGV----TLALGTPQGArTLRARIAVQAEGGLfHDQKADAGDSARRRDYGQTAIVGTVTVSApRPGW 208

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 293 AWQRFLPSGPIALLPIGD----NFSnIVWTMSPEEASRHKSMSSEDFVMSVNRAldFGygphpnsssldhyvERL--FSd 366
Cdd:PRK06996  209 AWERFTHEGPLALLPLGGprqaDYA-LVWCCAPDEAARRAALPDDAFLAELGAA--FG--------------TRMgrFT- 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 367 fggtaastkecfevppraigLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGvs 446
Cdd:PRK06996  271 --------------------RIAGRHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTLADALSDH-- 328

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 447 vGADIGDLSLLNRyendRKGANVAM-AAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAM 515
Cdd:PRK06996  329 -GATPLALATFAA----RRALDRRVtIGATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKHALARQMM 393
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 63-518 4.13e-26

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 109.63  E-value: 4.13e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  63 LDVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNpALKSTNYLKkdgipDSRVSTVTPATISFFRDIGAWEHILQqrh 142
Cdd:PRK06617    2 SNTVILGCGLSGMLTALSFAQ----KGIKTTIFESK-SVKSPEFFK-----DIRTTALTPHSKNFLFSIDIWEELEK--- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 143 aFFGKMQvwdytglgytrynasDVCkeylgcVVENKVlcnSLLLRLQEQKEDIEKMVYPTRLVSLAFPSKSRNVGVAGLK 222
Cdd:PRK06617   69 -FVAEMQ---------------DIY------VVDNKA---SEILDLRNDADAVLGYVVKNSDFKKILLSKITNNPLITLI 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 223 PPSTEAEELRRSNLVKLDLSDGQTLYSKLVVgADGSKSNVRQIAGIKTTGWSYpQSAIICTVEH-TAENDTAWQRFLPSG 301
Cdd:PRK06617  124 DNNQYQEVISHNDYSIIKFDDKQIKCNLLII-CDGANSKVRSHYFANEIEKPY-QTALTFNIKHeKPHENCAMEHFLPLG 201

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 302 PIALLPIGDNF-SNIVWTMSPEEASRHKSMSSE--DFVMSVNRALDFGygphpnsssldhyverlfsdfggtaastkecf 378
Cdd:PRK06617  202 PFALLPLKDQYaSSVIWSTSSDQAALIVNLPVEevRFLTQRNAGNSLG-------------------------------- 249

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 379 evpprAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGvsvgadigdlSLLN 458
Cdd:PRK06617  250 -----KITIDSEISSFPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSMIVSNN----------GTLQ 314

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 459 RYENDRKGANVAMAAVLDGFQKMYSVDFGPLNVLRAAAFHGAQYISPLKKNIISYAMGDR 518
Cdd:PRK06617  315 EYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYAMGKR 374
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 62-474 7.47e-14

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 72.74  E-value: 7.47e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  62 ELDVAIVGGGMVGLAVACALSnmplTKHLRVAVIDSNPALkstnylkkdgIPDSRVSTVTPATISFFRDIGAWEHILQQ- 140
Cdd:pfam01494   1 ETDVLIVGGGPAGLMLALLLA----RAGVRVVLVERHATT----------SVLPRAHGLNQRTMELLRQAGLEDRILAEg 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 141 -RHAFFGKMQvwdYTGLGYTRYNASDVCKEYLGCVvENKVLcNSLLLRLQEQKEDIEkmvYPTRLVSLafpsksrnvgva 219
Cdd:pfam01494  67 vPHEGMGLAF---YNTRRRADLDFLTSPPRVTVYP-QTELE-PILVEHAEARGAQVR---FGTEVLSL------------ 126

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 220 gLKPPSTEAEELRrsnlvklDLSDG--QTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICT------VEHTAEND 291
Cdd:pfam01494 127 -EQDGDGVTAVVR-------DRRDGeeYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVlfdapdLSDPVERA 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 292 T--AWQRFLPSGPIALLPIGDNFSN---IVWTMSPEEASRhksmsSEDFvmsvnraldfgygphpnssSLDHYVERLFSD 366
Cdd:pfam01494 199 FvhYLIYAPHSRGFMVGPWRSAGREryyVQVPWDEEVEER-----PEEF-------------------TDEELKQRLRSI 254

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 367 FGgtaastkecfevPPRAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEgvs 446
Cdd:pfam01494 255 VG------------IDLALVEILWKSIWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLAA--- 319

                         410       420
                  ....*....|....*....|....*...
gi 2123875648 447 VGADIGDLSLLNRYENDRkgANVAMAAV 474
Cdd:pfam01494 320 VLRGQAGESLLDTYSAER--LPVAWAVV 345
PRK07045 PRK07045
putative monooxygenase; Reviewed
 60-471 7.99e-14

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 73.02  E-value: 7.99e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  60 DDELDVAIVGGGMVGLAVACALSnmplTKHLRVAVIDS---NPALKSTNYLKKDGIpdsRVSTVTPATISFFRDIGAWEH 136
Cdd:PRK07045    3 NNPVDVLINGSGIAGVALAHLLG----ARGHSVTVVERaarNRAQNGADLLKPSGI---GVVRAMGLLDDVFAAGGLRRD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 137 ILQQRHaffgkmqvwDYTGLGYTRYNASDVCKEYLgcvvenKVLCNSLLlRLQEQKEDIEkmvyPTrlVSLAFPSKSRNV 216
Cdd:PRK07045   76 AMRLYH---------DKELIASLDYRSASALGYFI------LIPCEQLR-RLLLAKLDGL----PN--VRLRFETSIERI 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 217 gvaglkppsteaEELRRSNLVKLDLSDGQTLYSKLVVGADGSKSNVRQ-IAGIKTTGWSYPQSAIICTVEHTAENDTAWQ 295
Cdd:PRK07045  134 ------------ERDADGTVTSVTLSDGERVAPTVLVGADGARSMIRDdVLRMPAERVPYATPMAFGTIALTDSVRECNR 201

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 296 RFLPS--GPIALLPIGDNFSNIVWTMSPEEasrhksmsSEDFVMSVNRAldfgygphpnssSLDHYVERLFSDFGGTAAS 373
Cdd:PRK07045  202 LYVDSnqGLAYFYPIGDQATRLVVSFPADE--------MQGYLADTTRT------------KLLARLNEFVGDESADAMA 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 374 tkecfevpprAIGLISERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADIGD 453
Cdd:PRK07045  262 ----------AIGAGTAFPLIPLGRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDLHLSGQIALAD 331

                         410
                  ....*....|....*...
gi 2123875648 454 lsLLNRYENDRKGANVAM 471
Cdd:PRK07045  332 --ALERFERIRRPVNEAV 347
PRK06834 PRK06834
hypothetical protein; Provisional
 237-474 1.61e-13

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 72.74  E-value: 1.61e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 237 VKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHTAENDTAWQRflpsGPIALLPIG-DNFSNI 315
Cdd:PRK06834  133 VDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEWGVHR----DALGIHAFGrLEDEGP 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 316 VWTMSPEeasRHKSMSSEDFVMSVNRAL--DFG--YGPH-PNSSSldhyveRlFSDFGGTAAStkecfevppraiglise 390
Cdd:PRK06834  209 VRVMVTE---KQVGATGEPTLDDLREALiaVYGtdYGIHsPTWIS------R-FTDMARQAAS----------------- 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 391 rmafplslmhshdYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAA----ALAKVISeGVSvgADigdlSLLNRYENDRK- 465
Cdd:PRK06834  262 -------------YRDGRVLLAGDAAHVHSPVGGQGLNTGVQDAVnlgwKLAQVVK-GTS--PE----SLLDTYHAERHp 321

                         250
                  ....*....|...
gi 2123875648 466 -GANV---AMAAV 474
Cdd:PRK06834  322 vAARVlrnTMAQV 334
PRK08244 PRK08244
monooxygenase;
64-471 1.26e-11

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 66.69  E-value: 1.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSnmpLTKhLRVAVIDSnpaLKSTnylkkdgIPDSRVSTVTPATISFFRDIGAWEHILQQRHa 143
Cdd:PRK08244    4 EVIIIGGGPVGLMLASELA---LAG-VKTCVIER---LKET-------VPYSKALTLHPRTLEILDMRGLLERFLEKGR- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 144 ffgKMQVWDYTGLGyTRYNASdvckeylgcVVENKvlCNSLLLRLQEQKEDIekmvyptrlvslaFPSKSRNVGVAGLKp 223
Cdd:PRK08244   69 ---KLPSGHFAGLD-TRLDFS---------ALDTS--SNYTLFLPQAETEKV-------------LEEHARSLGVEIFR- 119

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 224 pstEAEEL---RRSNLVKLDLSDG---QTLYSKLVVGADGSKSNVRQIAGIKTTGWSYPQSAIICTV--EHTAENdTAWQ 295
Cdd:PRK08244  120 ---GAEVLavrQDGDGVEVVVRGPdglRTLTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVvlKDPPPS-SVLS 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 296 RFLPSGPIALLPIGDNFSNIVWTmSPE--EASRHKSMSSEDFVMSVNRAL--DFGYgphpNSSSldhyverLFSDFGGTA 371
Cdd:PRK08244  196 LCTREGGVMIVPLSGGIYRVLII-DPErpQVPKDEPVTLEELKTSLIRICgtDFGL----NDPV-------WMSRFGNAT 263

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 372 astkecfevppraigLISERmafplslmhshdYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALakviseGVSVGADI 451
Cdd:PRK08244  264 ---------------RQAER------------YRSGRIFLAGDAAHIHFPAGGQGLNVGLQDAMNL------GWKLAAAI 310

                         410       420
                  ....*....|....*....|...
gi 2123875648 452 GDLS---LLNRYENDRKGANVAM 471
Cdd:PRK08244  311 KGWApdwLLDSYHAERHPVGTAL 333
PRK06126 PRK06126
hypothetical protein; Provisional
 240-465 2.44e-08

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 56.54  E-value: 2.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 240 DLSDGQTL--YSKLVVGADGSKSNVRQIAGIK---TTGWSYPQSAIICTVEHTAendtawqrflpsgpiallPIGDNFSN 314
Cdd:PRK06126  166 DLDGGESLtiRADYLVGCDGARSAVRRSLGISyegTSGLQRDLSIYIRAPGLAA------------------LVGHDPAW 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 315 IVWTMSPEEASRHKSMS-SEDFVMSVNRALDfgygPHPNSSSLDHyVERLFSDFGGTAAstkecFEV----PPRAIGLIS 389
Cdd:PRK06126  228 MYWLFNPDRRGVLVAIDgRDEWLFHQLRGGE----DEFTIDDVDA-RAFVRRGVGEDID-----YEVlsvvPWTGRRLVA 297

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2123875648 390 ERmafplslmhshdYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVIsegVSVGADIGDLSLLNRYENDRK 465
Cdd:PRK06126  298 DS------------YRRGRVFLAGDAAHLFTPTGGYGMNTGIGDAVNLAWKL---AAVLNGWAGPALLDSYEAERR 358
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
70-461 9.75e-08

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 53.43  E-value: 9.75e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  70 GGMVGLAVACALSNmpltKHLRVAVIDsnpalkstnylkKDGIPDSRVST--VTPATISFFRDIGAWEHILQQRHaffgK 147
Cdd:COG0644     1 AGPAGSAAARRLAR----AGLSVLLLE------------KGSFPGDKICGggLLPRALEELEPLGLDEPLERPVR----G 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 148 MQVWDYTGlGYTRYNAsdvcKEYLGCVVENKVLCNSLLLRLQEQkediekmvyptrlvslafpsksrnvGVAGLkpPSTE 227
Cdd:COG0644    61 ARFYSPGG-KSVELPP----GRGGGYVVDRARFDRWLAEQAEEA-------------------------GAEVR--TGTR 108

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 228 AEELRRSN-LVKLDLSDGQTLYSKLVVGADGSKSNVRQIAGIKTTgWSYPQSAIICTVEHtaendtawqrflpsgpiall 306
Cdd:COG0644   109 VTDVLRDDgRVVVRTGDGEEIRADYVVDADGARSLLARKLGLKRR-SDEPQDYALAIKEH-------------------- 167

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 307 pigdnfsnivWTMSPEEASRHksmssEDFVMSVNRALDFGYGphpnsssldhYVerlFSDFGGTAAstkecfevppraIG 386
Cdd:COG0644   168 ----------WELPPLEGVDP-----GAVEFFFGEGAPGGYG----------WV---FPLGDGRVS------------VG 207

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2123875648 387 LisermafPLSLMHSHdYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGADigDLSLLNRYE 461
Cdd:COG0644   208 I-------PLGGPRPR-LVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAIAEALEGGDF--SAEALAEYE 272
PRK06184 PRK06184
hypothetical protein; Provisional
 64-476 1.43e-07

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 53.83  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPALkstnylkkdgIPDSRVSTVTPATISFFRDIGAWEHIL----- 138
Cdd:PRK06184    5 DVLIVGAGPTGLTLAIELAR----RGVSFRLIEKAPEP----------FPGSRGKGIQPRTQEVFDDLGVLDRVVaaggl 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 139 ---QQRHA---FFGKMQVWDYTGlgytryNASDVckEY-LGCVVENKVLCNSLLLRLQEQKEDIEkmvYPTRLVSLAFPS 211
Cdd:PRK06184   71 yppMRIYRddgSVAESDMFAHLE------PTPDE--PYpLPLMVPQWRTERILRERLAELGHRVE---FGCELVGFEQDA 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 212 KSRNVGVAGLkppsteaeelrrsnlvkldlSDGQTLYSKLVVGADGSKSNVRQIAGIKTTGWSY-PQSAIICTVEHTAEN 290
Cdd:PRK06184  140 DGVTARVAGP--------------------AGEETVRARYLVGADGGRSFVRKALGIGFPGETLgIDRMLVADVSLTGLD 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 291 DTAWQRFLPS--GPIALLPIGDnfsnivwtmspeeasrhksmsSEDF-VMSVnraldFGYGPHPNSSSldHYVERLFSDF 367
Cdd:PRK06184  200 RDAWHQWPDGdmGMIALCPLPG---------------------TDLFqIQAP-----LPPGGEPDLSA--DGLTALLAER 251

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 368 GGTAastkecfEVPPRAIGLISE-----RMAfplslmhsHDYVSKRLALVGDAAHtVHPLAG-QGVNLGFGDAA----AL 437
Cdd:PRK06184  252 TGRT-------DIRLHSVTWASAfrmnaRLA--------DRYRVGRVFLAGDAAH-VHPPAGgQGLNTSVQDAYnlgwKL 315

                         410       420       430
                  ....*....|....*....|....*....|....*....
gi 2123875648 438 AKVISegvsvGADIgdlSLLNRYENDRKgaNVAmAAVLD 476
Cdd:PRK06184  316 AAVLA-----GAPE---ALLDTYEEERR--PVA-AAVLG 343
PRK07190 PRK07190
FAD-binding protein;
241-465 1.05e-06

FAD-binding protein;


Pssm-ID: 235955 [Multi-domain]  Cd Length: 487  Bit Score: 51.35  E-value: 1.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 241 LSDGQTLYSKLVVGADGSKSNVRQ-----------------IAGIKTTgwSYPQSAIIcTVEHTAENDTAWqrfLP-SGP 302
Cdd:PRK07190  146 LSNGERIQSRYVIGADGSRSFVRNhfnvpfeiirpqiiwavIDGVIDT--DFPKVPEI-IVFQAETSDVAW---IPrEGE 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 303 IallpigDNFsnivwtmspeeasrHKSMSSEDFVMS-----VNRALDfgygPHpnssSLDHYVERLFSDFggtaaSTKEC 377
Cdd:PRK07190  220 I------DRF--------------YVRMDTKDFTLEqaiakINHAMQ----PH----RLGFKEIVWFSQF-----SVKES 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 378 fevppraiglISERMAfplslmhshdyVSKRLALVGDAAHtVHPL-AGQGVNLGFGDAAALAKVISEGVSVGAdigDLSL 456
Cdd:PRK07190  267 ----------VAEHFF-----------IQDRIFLAGDACH-IHSVnGGQGLNTGLADAFNLIWKLNMVIHHGA---SPEL 321


                  ....*....
gi 2123875648 457 LNRYENDRK 465
Cdd:PRK07190  322 LQSYEAERK 330
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
252-506 2.53e-06

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 49.91  E-value: 2.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 252 VVGADGSKSNVRQIAGIKTTGWSYPQSAIICTVEHTAENDTAWQRFL---PSGPIALLPIGDN-----FsnivwtM---- 319
Cdd:PRK06183  166 VVGCDGANSFVRRTLGVPFEDLTFPERWLVVDVLIANDPLGGPHTYQycdPARPYTSVRLPHGrrrweF------Mllpg 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 320 -SPEEasrhksMSSEDFVmsvnRALDFGYGPHPNSSSLDHYVERLFsdfggtaastkecfevppRAigliseRMAfplsl 398
Cdd:PRK06183  240 eTEEQ------LASPENV----WRLLAPWGPTPDDAELIRHAVYTF------------------HA------RVA----- 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 399 mhsHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALA-K---VISEGVsvgadigDLSLLNRYENDRKGANVAMAAV 474
Cdd:PRK06183  281 ---DRWRSGRVLLAGDAAHLMPPFAGQGMNSGIRDAANLAwKlaaVLRGRA-------GDALLDTYEQERRPHARAMIDL 350

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2123875648 475 LDGFQKMYSVDFGPLNVLRAAAFH-GAQYISPL 506
Cdd:PRK06183  351 AVRLGRVICPTDRLAAALRDAVLPvGTLFPQPR 383
PRK06185 PRK06185
FAD-dependent oxidoreductase;
409-474 7.76e-06

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 48.32  E-value: 7.76e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2123875648 409 LALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEGVSVGAdiGDLSLLNRYENDRKGANVAMAAV 474
Cdd:PRK06185  286 LLCIGDAAHAMSPVGGVGINLAIQDAVAAANILAEPLRRGR--VSDRDLAAVQRRREFPTRVTQAL 349
PRK06475 PRK06475
FAD-binding protein;
242-493 8.30e-06

FAD-binding protein;


Pssm-ID: 180582 [Multi-domain]  Cd Length: 400  Bit Score: 48.28  E-value: 8.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 242 SDGQTLYSK-LVVGADGSKSNVRQIAGIKTTGWS-------------YPQSaiICTVEHTAENDTAWqrFLPSGPIALLP 307
Cdd:PRK06475  148 TNSVETVSAaYLIACDGVWSMLRAKAGFSKARFSghiawrttlaadaLPAS--FLSAMPEHKAVSAW--LGNKAHFIAYP 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 308 IGD----NFSNIVWTMSPEEASRHKSmssedfvmsvnraldfgygphpnssslDHyvERLFSDFGGTAASTKECFEVppr 383
Cdd:PRK06475  224 VKGgkffNFVAITGGENPGEVWSKTG---------------------------DK--AHLKSIYADWNKPVLQILAA--- 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 384 aiglISERMAFPLSLMHSHDYVS-KRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVIsegvsvgaDIGDLS-LLNRYE 461
Cdd:PRK06475  272 ----IDEWTYWPLFEMADAQFVGpDRTIFLGDASHAVTPFAAQGAAMAIEDAAALAEAL--------DSDDQSaGLKRFD 339

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2123875648 462 NDRKGANVAMAAVLDgFQKMYSVDFGPLNVLR 493
Cdd:PRK06475  340 SVRKERIAAVAKRGQ-LNRFAYHATGIFALGR 370
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 64-101 3.55e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 42.77  E-value: 3.55e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2123875648  64 DVAIVGGGMVGLAVACALSnmplTKHLRVAVIDSNPAL 101
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELA----RRGLSVTLLERGDDP 34
PRK07236 PRK07236
hypothetical protein; Provisional
 387-473 6.83e-04

hypothetical protein; Provisional


Pssm-ID: 235980 [Multi-domain]  Cd Length: 386  Bit Score: 42.22  E-value: 6.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 387 LISERMAFplslmhshdyvsKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISegvSVGADIGdlSLLNRYENDRKG 466
Cdd:PRK07236  297 LEVPRMAF------------GRVALLGDAAFVARPHTAAGVAKAAADAVALAEALA---AAAGDID--AALAAWEAERLA 359


                  ....*..
gi 2123875648 467 ANVAMAA 473
Cdd:PRK07236  360 VGAAIVA 366
PRK08255 PRK08255
bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;
401-483 7.21e-04

bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;


Pssm-ID: 236203 [Multi-domain]  Cd Length: 765  Bit Score: 42.23  E-value: 7.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 401 SHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEgvsVGADIGDlsLLNRYENDRK--------GA----- 467
Cdd:PRK08255  263 VHWNRRVPVVLMGDAAHTAHFSIGSGTKLALEDAIELARCLHE---HPGDLPA--ALAAYEEERRvevlriqnAArnste 337

                          90
                  ....*....|....*....
gi 2123875648 468 ---NVAMAAVLDGFQKMYS 483
Cdd:PRK08255  338 wfeNVERYAGLEPEQFAYS 356
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 408-460 8.19e-04

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 41.71  E-value: 8.19e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2123875648 408 RLALVGDAAHTVHPLAGQGVNLgfgdAAALAKVISEGVSVGADIGDLSLLNRY 460
Cdd:PRK08243  280 RLFLAGDAAHIVPPTGAKGLNL----AASDVRYLARALVEFYREGDTALLDAY 328
PLN02927 PLN02927
antheraxanthin epoxidase/zeaxanthin epoxidase
 408-492 1.34e-03

antheraxanthin epoxidase/zeaxanthin epoxidase


Pssm-ID: 178515 [Multi-domain]  Cd Length: 668  Bit Score: 41.62  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 408 RLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISEG----VSVGADIGDLSLLNRYENDRK------GANVAMAAVLDG 477
Cdd:PLN02927  368 RVTLLGDSIHAMQPNMGQGGCMAIEDSFQLALELDEAwkqsVETNTPVDVVSSLKRYEESRRlrvaiiHAMARMAAIMAS 447

                          90
                  ....*....|....*.
gi 2123875648 478 FQKMY-SVDFGPLNVL 492
Cdd:PLN02927  448 TYKAYlGVGLGPLSFL 463
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
64-101 3.34e-03

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 39.74  E-value: 3.34e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2123875648  64 DVAIVGGGMVGLAVACALSnmpLTKHLRVAVIDSNPAL 101
Cdd:COG0579     6 DVVIIGAGIVGLALARELS---RYEDLKVLVLEKEDDV 40
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
64-100 4.67e-03

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 39.50  E-value: 4.67e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2123875648  64 DVAIVGGGMVGLAVACALSNmpltKHLRVAVIDSNPA 100
Cdd:COG0665     4 DVVVIGGGIAGLSTAYHLAR----RGLDVTVLERGRP 36
PRK00685 PRK00685
metal-dependent hydrolase; Provisional
 303-326 6.33e-03

metal-dependent hydrolase; Provisional


Pssm-ID: 234811 [Multi-domain]  Cd Length: 228  Bit Score: 38.25  E-value: 6.33e-03
                          10        20
                  ....*....|....*....|....
gi 2123875648 303 IALLPIGDNFsnivwTMSPEEASR 326
Cdd:PRK00685  160 VALLPIGDNF-----TMGPEDAAL 178
SE pfam08491
Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which ...
 393-497 7.66e-03

Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.


Pssm-ID: 400679  Cd Length: 276  Bit Score: 38.47  E-value: 7.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2123875648 393 AFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVISegvsvgaDIGDLS-------LLNRYENDRK 465
Cdd:pfam08491 116 SMPNSFLPASKNRKKGLILLGDALNMRHPLTGGGMTVGLNDIVLLRKLLG-------PLRDLSdrekvskVLKSFHWKRK 188

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2123875648 466 GanvaMAAVL----DGFQKMYSVDFGPLNVLRAAAF 497
Cdd:pfam08491 189 P----YDAVIntlsIALYSLFAADSDELKALRKGCF 220
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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