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Conserved domains on  [gi|2092231403|ref|XP_043396651|]
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beta-galactosidase isoform X4 [Chelonia mydas]

Protein Classification

glycoside hydrolase family 35 protein( domain architecture ID 10472897)

glycoside hydrolase family 35 protein similar to Xanthomonas phaseoli beta-galactosidase that catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides

CAZY:  GH35
EC:  3.2.1.-
Gene Ontology:  GO:0004565|GO:0005975
SCOP:  4003303

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Glyco_hydro_35 pfam01301
Glycosyl hydrolases family 35;
79-393 1.67e-163

Glycosyl hydrolases family 35;


:

Pssm-ID: 396048 [Multi-domain]  Cd Length: 316  Bit Score: 467.50  E-value: 1.67e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403  79 FLKDGKPFRYISGSIHYSRVPRYYWKDRLVKMKMAGLDAIQTYVPWNYHEFKPGVYNFYGDRDIKYFLELANEIGLLVIL 158
Cdd:pfam01301   2 FLIDGKRFRLISGSIHYFRIPPEMWPDRLQKAKALGLNAIETYVFWNLHEPEPGQYDFSGILDLVKFIKLAQEAGLYVIL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 159 RAGPYICAEWDMGGLPAWLLEKESIVLRSSDLDYLEAVDRWMGVLLPKMKPHLYQNGGPVIMVQVENEYGSYfACDYDYL 238
Cdd:pfam01301  82 RPGPYICAEWDFGGLPAWLLTVPGIRLRTSDPPFLEAVERYLTALLPKMKPLQATNGGPIIMVQVENEYGSY-GVDKAYL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 239 RHLQKLFHRHLGDEVVLFTTDGANKYYLRCGALQG--LYATVDFAPGGNVTAAFLTQRGSEPRGPLVNSEFYTGWLDHWG 316
Cdd:pfam01301 161 RALRKAYKEWGADMALLFTTDGPWGMCLQCGDLPGpdIYATNGFGCGANPPSNFKLLRPFSPNKPLMWSEFWTGWFDHWG 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2092231403 317 HPHSVVPTNTIAKTLDEILARGANVNMYMFIGGTNFAYWNGANMPYsSQPTSYDYDAPLSEAGDLTDKYFALREVIG 393
Cdd:pfam01301 241 GPHAIRPAEDIAFEVARFLAKNSSVNLYMFHGGTNFGFTNGANFYG-PQTTSYDYDAPIDEAGDPTPKYGHLKDLIT 316
 
Name Accession Description Interval E-value
Glyco_hydro_35 pfam01301
Glycosyl hydrolases family 35;
79-393 1.67e-163

Glycosyl hydrolases family 35;


Pssm-ID: 396048 [Multi-domain]  Cd Length: 316  Bit Score: 467.50  E-value: 1.67e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403  79 FLKDGKPFRYISGSIHYSRVPRYYWKDRLVKMKMAGLDAIQTYVPWNYHEFKPGVYNFYGDRDIKYFLELANEIGLLVIL 158
Cdd:pfam01301   2 FLIDGKRFRLISGSIHYFRIPPEMWPDRLQKAKALGLNAIETYVFWNLHEPEPGQYDFSGILDLVKFIKLAQEAGLYVIL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 159 RAGPYICAEWDMGGLPAWLLEKESIVLRSSDLDYLEAVDRWMGVLLPKMKPHLYQNGGPVIMVQVENEYGSYfACDYDYL 238
Cdd:pfam01301  82 RPGPYICAEWDFGGLPAWLLTVPGIRLRTSDPPFLEAVERYLTALLPKMKPLQATNGGPIIMVQVENEYGSY-GVDKAYL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 239 RHLQKLFHRHLGDEVVLFTTDGANKYYLRCGALQG--LYATVDFAPGGNVTAAFLTQRGSEPRGPLVNSEFYTGWLDHWG 316
Cdd:pfam01301 161 RALRKAYKEWGADMALLFTTDGPWGMCLQCGDLPGpdIYATNGFGCGANPPSNFKLLRPFSPNKPLMWSEFWTGWFDHWG 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2092231403 317 HPHSVVPTNTIAKTLDEILARGANVNMYMFIGGTNFAYWNGANMPYsSQPTSYDYDAPLSEAGDLTDKYFALREVIG 393
Cdd:pfam01301 241 GPHAIRPAEDIAFEVARFLAKNSSVNLYMFHGGTNFGFTNGANFYG-PQTTSYDYDAPIDEAGDPTPKYGHLKDLIT 316
GanA COG1874
Beta-galactosidase GanA [Carbohydrate transport and metabolism];
84-524 3.93e-52

Beta-galactosidase GanA [Carbohydrate transport and metabolism];


Pssm-ID: 441478 [Multi-domain]  Cd Length: 609  Bit Score: 187.83  E-value: 3.93e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403  84 KPFRYISGSIHYSRVPRYYWKDRLVKMKMAGLDAIQT-YVPWNYHEFKPGVYNFYG-DRdikyFLELANEIGLLVILRAG 161
Cdd:COG1874     7 KPFLILGGDYHPERWPPEVWAEDIRLMKAAGLNTVRIgYFAWNLHEPEEGVFDFDWlDR----FIDLLHEAGLKVILRTP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 162 PYIcaewdmggLPAWLLEKESIVLR-----------------SSDLDYLEAVDRWMGVLLPKmkphlYQNGGPVIMVQVE 224
Cdd:COG1874    83 TAA--------PPAWLLKKYPEILPvdadgrrrgfgsrrhycPSSPVYREAARRIVRALAER-----YGDHPAVIMWQVD 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 225 NEYGSYFACDY-----------------------------------------------------------------DYLR 239
Cdd:COG1874   150 NEYGSYDYCDAcaaafrdwlrerygtldalneawgtafwsqrytdwdeiepprltpttanpslrldfrrfssdqvlEYLR 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 240 HLQKLFHRHlGDEVVLFTTDGANKY---YLRCGALQGLYATVDFAPGGNVTAAFLT-----QRGSEPRGPLVNSEFYTGW 311
Cdd:COG1874   230 AQRDILREA-GPDVPVTTNFMGPFPgldYWKLARDLDVVSWDNYPDGSAADPDEIAfahdlMRGLKGGGPFMVMEQWPGW 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 312 LdHWGHPHSVVPTNTIAKTLDEILARGAN-VNMYMF---IGGtnfaywnganmpyssqpTSYDYDAPLSEAGDLTDKYFA 387
Cdd:COG1874   309 V-NWGPYNPAKRPGQLRLWSLQALAHGADgVNYFQWrpsRGG-----------------TEYDHDAPLDHAGRPTRKFRE 370
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 388 LREVIGRYKHLPEGPIPPTTPKyaygqvameklgtVAELLDDLSpsgpiRSTYPLSFVQLQQYFGFV-----LYRTTLpk 462
Cdd:COG1874   371 VRELGAELARLPEVPGSRVTAR-------------VALLFDWES-----WWALEIQSPPLGQDLGYVdlvraLYRALR-- 430
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2092231403 463 ncseptplfsplngvhdRAYVSVDGVPQGV-LERGK------SYIinITGKAGANLDVLVENMGRVNYG 524
Cdd:COG1874   431 -----------------RAGVTVDIVPPFAdLSGYKllvapaLYL--VSDALAERLLAYVENGGRVNYG 480
PLN03059 PLN03059
beta-galactosidase; Provisional
72-391 6.85e-46

beta-galactosidase; Provisional


Pssm-ID: 166698 [Multi-domain]  Cd Length: 840  Bit Score: 172.88  E-value: 6.85e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403  72 IDYDNNYFLKDGKPFRYISGSIHYSRVPRYYWKDRLVKMKMAGLDAIQTYVPWNYHEFKPGVYNFYGDRDIKYFLELANE 151
Cdd:PLN03059   30 VSYDHRAFIINGQRRILISGSIHYPRSTPEMWPDLIQKAKDGGLDVIQTYVFWNGHEPSPGNYYFEDRYDLVKFIKVVQA 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 152 IGLLVILRAGPYICAEWDMGGLPAWLLEKESIVLRSSDLDYLEAVDRWMGVLLPKMKPH-LYQN-GGPVIMVQVENEYGs 229
Cdd:PLN03059  110 AGLYVHLRIGPYICAEWNFGGFPVWLKYVPGIEFRTDNGPFKAAMQKFTEKIVDMMKSEkLFEPqGGPIILSQIENEYG- 188
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 230 yfACDYDyLRHLQKLFHRHLGDEVVLFttdGANKYYLRCGALQGLYATVDfAPGGNVTAAFLTQRGSEPRgplVNSEFYT 309
Cdd:PLN03059  189 --PVEWE-IGAPGKAYTKWAADMAVKL---GTGVPWVMCKQEDAPDPVID-TCNGFYCENFKPNKDYKPK---MWTEAWT 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 310 GWLDHWGHPHSVVPTNTIAKTLDE-ILARGANVNMYMFIGGTNFAYWNGAnmPYSSqpTSYDYDAPLSEAGDLTD-KYFA 387
Cdd:PLN03059  259 GWYTEFGGAVPNRPAEDLAFSVARfIQNGGSFINYYMYHGGTNFGRTAGG--PFIA--TSYDYDAPLDEYGLPREpKWGH 334

                  ....
gi 2092231403 388 LREV 391
Cdd:PLN03059  335 LRDL 338
 
Name Accession Description Interval E-value
Glyco_hydro_35 pfam01301
Glycosyl hydrolases family 35;
79-393 1.67e-163

Glycosyl hydrolases family 35;


Pssm-ID: 396048 [Multi-domain]  Cd Length: 316  Bit Score: 467.50  E-value: 1.67e-163
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403  79 FLKDGKPFRYISGSIHYSRVPRYYWKDRLVKMKMAGLDAIQTYVPWNYHEFKPGVYNFYGDRDIKYFLELANEIGLLVIL 158
Cdd:pfam01301   2 FLIDGKRFRLISGSIHYFRIPPEMWPDRLQKAKALGLNAIETYVFWNLHEPEPGQYDFSGILDLVKFIKLAQEAGLYVIL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 159 RAGPYICAEWDMGGLPAWLLEKESIVLRSSDLDYLEAVDRWMGVLLPKMKPHLYQNGGPVIMVQVENEYGSYfACDYDYL 238
Cdd:pfam01301  82 RPGPYICAEWDFGGLPAWLLTVPGIRLRTSDPPFLEAVERYLTALLPKMKPLQATNGGPIIMVQVENEYGSY-GVDKAYL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 239 RHLQKLFHRHLGDEVVLFTTDGANKYYLRCGALQG--LYATVDFAPGGNVTAAFLTQRGSEPRGPLVNSEFYTGWLDHWG 316
Cdd:pfam01301 161 RALRKAYKEWGADMALLFTTDGPWGMCLQCGDLPGpdIYATNGFGCGANPPSNFKLLRPFSPNKPLMWSEFWTGWFDHWG 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2092231403 317 HPHSVVPTNTIAKTLDEILARGANVNMYMFIGGTNFAYWNGANMPYsSQPTSYDYDAPLSEAGDLTDKYFALREVIG 393
Cdd:pfam01301 241 GPHAIRPAEDIAFEVARFLAKNSSVNLYMFHGGTNFGFTNGANFYG-PQTTSYDYDAPIDEAGDPTPKYGHLKDLIT 316
GanA COG1874
Beta-galactosidase GanA [Carbohydrate transport and metabolism];
84-524 3.93e-52

Beta-galactosidase GanA [Carbohydrate transport and metabolism];


Pssm-ID: 441478 [Multi-domain]  Cd Length: 609  Bit Score: 187.83  E-value: 3.93e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403  84 KPFRYISGSIHYSRVPRYYWKDRLVKMKMAGLDAIQT-YVPWNYHEFKPGVYNFYG-DRdikyFLELANEIGLLVILRAG 161
Cdd:COG1874     7 KPFLILGGDYHPERWPPEVWAEDIRLMKAAGLNTVRIgYFAWNLHEPEEGVFDFDWlDR----FIDLLHEAGLKVILRTP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 162 PYIcaewdmggLPAWLLEKESIVLR-----------------SSDLDYLEAVDRWMGVLLPKmkphlYQNGGPVIMVQVE 224
Cdd:COG1874    83 TAA--------PPAWLLKKYPEILPvdadgrrrgfgsrrhycPSSPVYREAARRIVRALAER-----YGDHPAVIMWQVD 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 225 NEYGSYFACDY-----------------------------------------------------------------DYLR 239
Cdd:COG1874   150 NEYGSYDYCDAcaaafrdwlrerygtldalneawgtafwsqrytdwdeiepprltpttanpslrldfrrfssdqvlEYLR 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 240 HLQKLFHRHlGDEVVLFTTDGANKY---YLRCGALQGLYATVDFAPGGNVTAAFLT-----QRGSEPRGPLVNSEFYTGW 311
Cdd:COG1874   230 AQRDILREA-GPDVPVTTNFMGPFPgldYWKLARDLDVVSWDNYPDGSAADPDEIAfahdlMRGLKGGGPFMVMEQWPGW 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 312 LdHWGHPHSVVPTNTIAKTLDEILARGAN-VNMYMF---IGGtnfaywnganmpyssqpTSYDYDAPLSEAGDLTDKYFA 387
Cdd:COG1874   309 V-NWGPYNPAKRPGQLRLWSLQALAHGADgVNYFQWrpsRGG-----------------TEYDHDAPLDHAGRPTRKFRE 370
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 388 LREVIGRYKHLPEGPIPPTTPKyaygqvameklgtVAELLDDLSpsgpiRSTYPLSFVQLQQYFGFV-----LYRTTLpk 462
Cdd:COG1874   371 VRELGAELARLPEVPGSRVTAR-------------VALLFDWES-----WWALEIQSPPLGQDLGYVdlvraLYRALR-- 430
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2092231403 463 ncseptplfsplngvhdRAYVSVDGVPQGV-LERGK------SYIinITGKAGANLDVLVENMGRVNYG 524
Cdd:COG1874   431 -----------------RAGVTVDIVPPFAdLSGYKllvapaLYL--VSDALAERLLAYVENGGRVNYG 480
PLN03059 PLN03059
beta-galactosidase; Provisional
72-391 6.85e-46

beta-galactosidase; Provisional


Pssm-ID: 166698 [Multi-domain]  Cd Length: 840  Bit Score: 172.88  E-value: 6.85e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403  72 IDYDNNYFLKDGKPFRYISGSIHYSRVPRYYWKDRLVKMKMAGLDAIQTYVPWNYHEFKPGVYNFYGDRDIKYFLELANE 151
Cdd:PLN03059   30 VSYDHRAFIINGQRRILISGSIHYPRSTPEMWPDLIQKAKDGGLDVIQTYVFWNGHEPSPGNYYFEDRYDLVKFIKVVQA 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 152 IGLLVILRAGPYICAEWDMGGLPAWLLEKESIVLRSSDLDYLEAVDRWMGVLLPKMKPH-LYQN-GGPVIMVQVENEYGs 229
Cdd:PLN03059  110 AGLYVHLRIGPYICAEWNFGGFPVWLKYVPGIEFRTDNGPFKAAMQKFTEKIVDMMKSEkLFEPqGGPIILSQIENEYG- 188
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 230 yfACDYDyLRHLQKLFHRHLGDEVVLFttdGANKYYLRCGALQGLYATVDfAPGGNVTAAFLTQRGSEPRgplVNSEFYT 309
Cdd:PLN03059  189 --PVEWE-IGAPGKAYTKWAADMAVKL---GTGVPWVMCKQEDAPDPVID-TCNGFYCENFKPNKDYKPK---MWTEAWT 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 310 GWLDHWGHPHSVVPTNTIAKTLDE-ILARGANVNMYMFIGGTNFAYWNGAnmPYSSqpTSYDYDAPLSEAGDLTD-KYFA 387
Cdd:PLN03059  259 GWYTEFGGAVPNRPAEDLAFSVARfIQNGGSFINYYMYHGGTNFGRTAGG--PFIA--TSYDYDAPLDEYGLPREpKWGH 334

                  ....
gi 2092231403 388 LREV 391
Cdd:PLN03059  335 LRDL 338
Glyco_hydro_42 pfam02449
Beta-galactosidase; This group of beta-galactosidase enzymes belong to the glycosyl hydrolase ...
97-249 1.97e-09

Beta-galactosidase; This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.


Pssm-ID: 396834  Cd Length: 376  Bit Score: 59.59  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403  97 RVPRYYWKDRLVKMKMAGLDAIQ-TYVPWNYHEFKPGVYNFYG-DRdikyFLELANEIGLLVILRAGpyicaewdMGGLP 174
Cdd:pfam02449   6 QWPEETWEEDIRLMKEAGVNVVRiGIFAWAKLEPEEGKYDFEWlDE----VIDLLAKAGIKVILATP--------TAAPP 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2092231403 175 AWLLEKESIVLR------------------SSDLdYLEAVDRWMGVLlpkmkPHLYQNGGPVIMVQVENEYGSYFacDYD 236
Cdd:pfam02449  74 AWLVKKHPEILPvdadgrrrgfgsrhhycpSSPV-YREYAARIVEAL-----AERYGDHPALIGWHIDNEYGCHV--SEC 145
                         170
                  ....*....|...
gi 2092231403 237 YLRHLQKLFHRHL 249
Cdd:pfam02449 146 YCETCERAFRKWL 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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