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Conserved domains on  [gi|2038122266|ref|XP_041437813|]
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sodium-dependent phosphate transporter 2 isoform X2 [Xenopus laevis]

Protein Classification

inorganic phosphate transporter( domain architecture ID 10475700)

inorganic phosphate transporter is involved in phosphate transport, such as bacterial low-affinity inorganic phosphate transporter and vertebrate sodium-dependent phosphate transporters, which play fundamental housekeeping roles in phosphate transport

Gene Ontology:  GO:0005315|GO:0006817|GO:0016020
TCDB:  2.A.20

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
478-638 2.60e-71

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


:

Pssm-ID: 460184  Cd Length: 322  Bit Score: 233.55  E-value: 2.60e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 478 EKDKSQVHLLFHFLQILTACFGSFAHGGNDVSNAIGPLV-ALWLIYQQGGVMQEASTPVWLLLYGGVGICAGLWVWGRRV 556
Cdd:pfam01384 161 AKYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRI 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 557 IQTMGKDLTPITPSSGFCIEVMCAITVLVSSNVGIPISSTHCKVGSVVAVGWIRSRKAVDWRLFRNIFLAWFVTVPVAGL 636
Cdd:pfam01384 241 IKTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAAL 320

                  ..
gi 2038122266 637 FS 638
Cdd:pfam01384 321 LS 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
25-232 2.67e-64

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


:

Pssm-ID: 460184  Cd Length: 322  Bit Score: 215.06  E-value: 2.67e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266  25 GANDVANSFGTAVGSGVVTLRQACILASIFETIGSVLLGAKVGETIRKGIIDVNLynnTVDLLMAGEVSAMVGSAVWQLI 104
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 105 ASFLKLPVSGTHCIVGATIGFSLVAVGAHSVQWMQLVKIVASWFISPLLSGLMSGALFLMIKFFILNKEDP--------- 175
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPlkalrllpg 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2038122266 176 ---------VPNGLKALPVFYAA-------------TIGINVFSILFTGAPLLGLQTFPVWATALLSVGIAIVFALVVW 232
Cdd:pfam01384 158 lirakydnkVERLFRFLQILSAAlvsfahgandvqnAMGPLTAALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTG 236
 
Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
478-638 2.60e-71

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 233.55  E-value: 2.60e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 478 EKDKSQVHLLFHFLQILTACFGSFAHGGNDVSNAIGPLV-ALWLIYQQGGVMQEASTPVWLLLYGGVGICAGLWVWGRRV 556
Cdd:pfam01384 161 AKYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRI 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 557 IQTMGKDLTPITPSSGFCIEVMCAITVLVSSNVGIPISSTHCKVGSVVAVGWIRSRKAVDWRLFRNIFLAWFVTVPVAGL 636
Cdd:pfam01384 241 IKTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAAL 320

                  ..
gi 2038122266 637 FS 638
Cdd:pfam01384 321 LS 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
25-232 2.67e-64

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 215.06  E-value: 2.67e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266  25 GANDVANSFGTAVGSGVVTLRQACILASIFETIGSVLLGAKVGETIRKGIIDVNLynnTVDLLMAGEVSAMVGSAVWQLI 104
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 105 ASFLKLPVSGTHCIVGATIGFSLVAVGAHSVQWMQLVKIVASWFISPLLSGLMSGALFLMIKFFILNKEDP--------- 175
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPlkalrllpg 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2038122266 176 ---------VPNGLKALPVFYAA-------------TIGINVFSILFTGAPLLGLQTFPVWATALLSVGIAIVFALVVW 232
Cdd:pfam01384 158 lirakydnkVERLFRFLQILSAAlvsfahgandvqnAMGPLTAALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTG 236
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
482-646 3.15e-47

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 169.19  E-value: 3.15e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 482 SQVHLLFHFLQILTACFGSFAHGGNDVSNAIGPLVALWLIyqqGGVMQEASTPVWLLLYGGVGICAGLWVWGRRVIQTMG 561
Cdd:COG0306   166 RRVNRGFRRLQIVSAALMAFSHGANDAQKAMGIITLALLA---AGLLSGFEVPLWVILLCALAIALGTLLGGWRIIKTLG 242
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 562 KDLTPITPSSGFCIEVMCAITVLVSSNVGIPISSTHCKVGSVVAVGWIRSRKAVDWRLFRNIFLAWFVTVPVAGLFSAGV 641
Cdd:COG0306   243 KKITKLDPLQGFAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGAARRLSAVRWGVAGRIVLAWVLTLPAAALLAALL 322

                  ....*
gi 2038122266 642 MAILQ 646
Cdd:COG0306   323 YLLLS 327
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
7-225 6.75e-43

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 157.25  E-value: 6.75e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266   7 LWMVIVGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETIGSVLLGAKVGETIRKGIIDVnlynNTVDL 86
Cdd:COG0306     4 LLLLIVVILLALFFDFNNGFHDAANAIATAVGTRALSPRTAVLLAAVFNFLGALLFGTAVAKTIGKGIVDP----GILTL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266  87 LMAgeVSAMVGSAVWQLIASFLKLPVSGTHCIVGATIGFSLVAVGAHSVQWMQLVKIVASWFISPLLSGLMSGALFLMIK 166
Cdd:COG0306    80 EVV--LAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLAAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLLY 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2038122266 167 FFILNKE-DPVPNGLKALPVFYAA-------------TIGINVFSILFTGapLLGLQTFPVWATALLSVGIAI 225
Cdd:COG0306   158 WLFRRANpRRVNRGFRRLQIVSAAlmafshgandaqkAMGIITLALLAAG--LLSGFEVPLWVILLCALAIAL 228
 
Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
478-638 2.60e-71

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 233.55  E-value: 2.60e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 478 EKDKSQVHLLFHFLQILTACFGSFAHGGNDVSNAIGPLV-ALWLIYQQGGVMQEASTPVWLLLYGGVGICAGLWVWGRRV 556
Cdd:pfam01384 161 AKYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRI 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 557 IQTMGKDLTPITPSSGFCIEVMCAITVLVSSNVGIPISSTHCKVGSVVAVGWIRSRKAVDWRLFRNIFLAWFVTVPVAGL 636
Cdd:pfam01384 241 IKTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAAL 320

                  ..
gi 2038122266 637 FS 638
Cdd:pfam01384 321 LS 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
25-232 2.67e-64

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 215.06  E-value: 2.67e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266  25 GANDVANSFGTAVGSGVVTLRQACILASIFETIGSVLLGAKVGETIRKGIIDVNLynnTVDLLMAGEVSAMVGSAVWQLI 104
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 105 ASFLKLPVSGTHCIVGATIGFSLVAVGAHSVQWMQLVKIVASWFISPLLSGLMSGALFLMIKFFILNKEDP--------- 175
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPlkalrllpg 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2038122266 176 ---------VPNGLKALPVFYAA-------------TIGINVFSILFTGAPLLGLQTFPVWATALLSVGIAIVFALVVW 232
Cdd:pfam01384 158 lirakydnkVERLFRFLQILSAAlvsfahgandvqnAMGPLTAALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTG 236
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
482-646 3.15e-47

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 169.19  E-value: 3.15e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 482 SQVHLLFHFLQILTACFGSFAHGGNDVSNAIGPLVALWLIyqqGGVMQEASTPVWLLLYGGVGICAGLWVWGRRVIQTMG 561
Cdd:COG0306   166 RRVNRGFRRLQIVSAALMAFSHGANDAQKAMGIITLALLA---AGLLSGFEVPLWVILLCALAIALGTLLGGWRIIKTLG 242
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 562 KDLTPITPSSGFCIEVMCAITVLVSSNVGIPISSTHCKVGSVVAVGWIRSRKAVDWRLFRNIFLAWFVTVPVAGLFSAGV 641
Cdd:COG0306   243 KKITKLDPLQGFAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGAARRLSAVRWGVAGRIVLAWVLTLPAAALLAALL 322

                  ....*
gi 2038122266 642 MAILQ 646
Cdd:COG0306   323 YLLLS 327
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
7-225 6.75e-43

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 157.25  E-value: 6.75e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266   7 LWMVIVGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETIGSVLLGAKVGETIRKGIIDVnlynNTVDL 86
Cdd:COG0306     4 LLLLIVVILLALFFDFNNGFHDAANAIATAVGTRALSPRTAVLLAAVFNFLGALLFGTAVAKTIGKGIVDP----GILTL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266  87 LMAgeVSAMVGSAVWQLIASFLKLPVSGTHCIVGATIGFSLVAVGAHSVQWMQLVKIVASWFISPLLSGLMSGALFLMIK 166
Cdd:COG0306    80 EVV--LAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLAAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLLY 157
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2038122266 167 FFILNKE-DPVPNGLKALPVFYAA-------------TIGINVFSILFTGapLLGLQTFPVWATALLSVGIAI 225
Cdd:COG0306   158 WLFRRANpRRVNRGFRRLQIVSAAlmafshgandaqkAMGIITLALLAAG--LLSGFEVPLWVILLCALAIAL 228
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
14-169 6.21e-16

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 79.44  E-value: 6.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266  14 FIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQAC--------ILASIFETIGSVLLGAKVGETIRKGIIDVNLYNNtvd 85
Cdd:COG0306   177 IVSAALMAFSHGANDAQKAMGIITLALLAAGLLSGfevplwviLLCALAIALGTLLGGWRIIKTLGKKITKLDPLQG--- 253
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266  86 llmageVSAMVGSAVWQLIASFLKLPVSGTHCIVGATIGFSLvAVGAHSVQWMQLVKIVASWFISPLLSGLMSGALFLMI 165
Cdd:COG0306   254 ------FAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGA-ARRLSAVRWGVAGRIVLAWVLTLPAAALLAALLYLLL 326

                  ....
gi 2038122266 166 KFFI 169
Cdd:COG0306   327 SLLG 330
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
504-650 1.03e-15

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 78.70  E-value: 1.03e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 504 GGNDVSNAIGPLVAlwliyqqGGVMqeasTPVWLLLYGGVGICAGLWVWGRRVIQTMGKDLTPITPSSGFCIEVM----- 578
Cdd:pfam01384   1 GANDVANAFATSVG-------SRAL----TPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSFDPGVLMLGMlaall 69
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2038122266 579 -CAITVLVSSNVGIPISSTHCKVGSVVAVGW-IRSRKAVDWRLFRNIFLAWFVTVPVAGLFSAGVMAILQYGIL 650
Cdd:pfam01384  70 gAAIWLLIATYLGLPVSSTHALVGALIGAGLaAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLIL 143
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
15-158 2.32e-15

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 77.54  E-value: 2.32e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266  15 IIAFVLAFSVGANDVANSFG------------TAVGSGVVTLRQACILASIFETIGSVLLGAKVGETIRKGIIDVNLYNn 82
Cdd:pfam01384 177 LSAALVSFAHGANDVQNAMGpltaalyaigttGEVASKAPVPLWVLLLGALAIALGTWTGGWRIIKTVGNKITKLTPSR- 255
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2038122266  83 tvdllmaGeVSAMVGSAVWQLIASFLKLPVSGTHCIVGATIGFSLVAvGAHSVQWMQLVKIVASWFISPLLSGLMS 158
Cdd:pfam01384 256 -------G-FAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLAR-GLSAVNWGVVGNIVLAWVLTLPVAALLS 322
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
493-645 7.87e-14

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 72.89  E-value: 7.87e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038122266 493 ILTACFGSFAHGGNDVSNAIGPLVAlwliyqqGGVMqeasTPVWLLLYGGVGICAGLWVWGRRVIQTMGKDLTP---ITP 569
Cdd:COG0306    11 ILLALFFDFNNGFHDAANAIATAVG-------TRAL----SPRTAVLLAAVFNFLGALLFGTAVAKTIGKGIVDpgiLTL 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2038122266 570 SSGFCIEVMCAITVLVSSNVGIPISSTHCKVGSVVAVGW-IRSRKAVDWRLFRNIFLAWFVTVPVAGLFSAGVMAIL 645
Cdd:COG0306    80 EVVLAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLaAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLL 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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