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Conserved domains on  [gi|2025692012|ref|XP_040601840|]
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excitatory amino acid transporter 3 [Mesocricetus auratus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
16-467 1.03e-121

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 362.89  E-value: 1.03e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  16 RNNWLLLSTVAAVVLGIVIGVLVRGHSELsnldkfYFAFPGEILMRMLKLVILPLIISSMITGVAAL-DSNVSGKIGLRA 94
Cdd:COG1301     1 FKLSLTLQILIALVLGILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  95 VVYYFCTTIIAVILGIVLVVSIKPGVSqkVSEINRSGKSPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkpvsd 174
Cdd:COG1301    75 LLYFLVTTTIALVIGLVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA----------------- 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 175 pggnatevsvttamttmpknrtkeykivglYSDGiNVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIM 254
Cdd:COG1301   136 ------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVM 184
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 255 CYMPIGILFLIAGKIIEVeDWEIFRKLGLYMATVLSGLAIHSTVVLPLIYFIIVRKNPFRFALGMAQALLTALMISSSSA 334
Cdd:COG1301   185 KLAPIGVFALIAATVAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEA 263
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 335 TLPVTFRCAEEKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGAAGVPQAG 414
Cdd:COG1301   264 TLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAG 343
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2025692012 415 LVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 467
Cdd:COG1301   344 LVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
16-467 1.03e-121

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 362.89  E-value: 1.03e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  16 RNNWLLLSTVAAVVLGIVIGVLVRGHSELsnldkfYFAFPGEILMRMLKLVILPLIISSMITGVAAL-DSNVSGKIGLRA 94
Cdd:COG1301     1 FKLSLTLQILIALVLGILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  95 VVYYFCTTIIAVILGIVLVVSIKPGVSqkVSEINRSGKSPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkpvsd 174
Cdd:COG1301    75 LLYFLVTTTIALVIGLVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA----------------- 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 175 pggnatevsvttamttmpknrtkeykivglYSDGiNVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIM 254
Cdd:COG1301   136 ------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVM 184
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 255 CYMPIGILFLIAGKIIEVeDWEIFRKLGLYMATVLSGLAIHSTVVLPLIYFIIVRKNPFRFALGMAQALLTALMISSSSA 334
Cdd:COG1301   185 KLAPIGVFALIAATVAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEA 263
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 335 TLPVTFRCAEEKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGAAGVPQAG 414
Cdd:COG1301   264 TLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAG 343
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2025692012 415 LVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 467
Cdd:COG1301   344 LVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
SDF pfam00375
Sodium:dicarboxylate symporter family;
20-464 8.20e-119

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 354.91  E-value: 8.20e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  20 LLLSTVAAVVLGIVIGVLVRGHSElsnldkfYFAFPGEILMRMLKLVILPLIISSMITGVAAL-DSNVSGKIGLRAVVYY 98
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAA-------WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  99 FCTTIIAVILGIVLVVSIKPGVSQKVSEInrSGKSPEVSTVDAMLDLIRNMFPENLVQACFQQyktkreevkpvsdpggn 178
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAA--SLKEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 179 atevsvttamttmpknrtkeykivglysdgiNVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMP 258
Cdd:pfam00375 135 -------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAP 183
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 259 IGILFLIAGKIIEvEDWEIFRKLGLYMATVLSGLAIHSTVVLPLIYFIIVRKNPFRFALGMAQALLTALMISSSSATLPV 338
Cdd:pfam00375 184 IGVFALIANTVGT-YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPV 262
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 339 TFRCAEEKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGAAGVPQAGLVTM 418
Cdd:pfam00375 263 TLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVAL 342
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2025692012 419 VIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKL 464
Cdd:pfam00375 343 GLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
27-463 2.69e-43

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 159.16  E-value: 2.69e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  27 AVVLGIVIGVLVRGHSELSNLDKFYFAFP-GEILMRMLKLVILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTII 104
Cdd:PRK11283   15 ALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITTV 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 105 AVILGIVLVVSIKPGVSQKVSEInrsgkspevSTVDamldlirnmfpenlvqacFQQYKTKREEVKPVSdpggnatEVSV 184
Cdd:PRK11283   95 AIILGITLANVFQPGAGIDMSQL---------ATVD------------------ISKYQSTTEEVQSHS-------HGLM 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 185 TTAMTTMPKNrtkeykIVGLYSDGiNVLGLIIFCLVFGLVIGKMGEK-GQILVDFFNALSDATMKIVQIIMCYMPIGILF 263
Cdd:PRK11283  141 GTILSLIPTN------IFASMAKG-EMLPIIFFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVGVFA 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 264 LIAgkiIEVEDWEIFRKLGLYMATVLSGLAI--HSTVVLPLIYFIIvRKNPFRFALGMAQALLTALMISSSSATLPvtfR 341
Cdd:PRK11283  214 LIA---VTVANFGFASLWPLAKLVLLVYFAIlfFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLP---R 286
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 342 CAE--EKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGAAGVPQAGLVTMV 419
Cdd:PRK11283  287 IIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLL 366
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 2025692012 420 IVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 463
Cdd:PRK11283  367 ATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAK 410
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
16-467 1.03e-121

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 362.89  E-value: 1.03e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  16 RNNWLLLSTVAAVVLGIVIGVLVRGHSELsnldkfYFAFPGEILMRMLKLVILPLIISSMITGVAAL-DSNVSGKIGLRA 94
Cdd:COG1301     1 FKLSLTLQILIALVLGILLGLLLPELVAA------VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  95 VVYYFCTTIIAVILGIVLVVSIKPGVSqkVSEINRSGKSPEVSTVDAMLDLIRNMFPENLVQAcfqqyktkreevkpvsd 174
Cdd:COG1301    75 LLYFLVTTTIALVIGLVVANLFQPGAG--LNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA----------------- 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 175 pggnatevsvttamttmpknrtkeykivglYSDGiNVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIM 254
Cdd:COG1301   136 ------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVM 184
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 255 CYMPIGILFLIAGKIIEVeDWEIFRKLGLYMATVLSGLAIHSTVVLPLIYFIIVRKNPFRFALGMAQALLTALMISSSSA 334
Cdd:COG1301   185 KLAPIGVFALIAATVAKY-GLDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEA 263
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 335 TLPVTFRCAEEKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGAAGVPQAG 414
Cdd:COG1301   264 TLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAG 343
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2025692012 415 LVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 467
Cdd:COG1301   344 LVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGE 396
SDF pfam00375
Sodium:dicarboxylate symporter family;
20-464 8.20e-119

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 354.91  E-value: 8.20e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  20 LLLSTVAAVVLGIVIGVLVRGHSElsnldkfYFAFPGEILMRMLKLVILPLIISSMITGVAAL-DSNVSGKIGLRAVVYY 98
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAA-------WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  99 FCTTIIAVILGIVLVVSIKPGVSQKVSEInrSGKSPEVSTVDAMLDLIRNMFPENLVQACFQQyktkreevkpvsdpggn 178
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAA--SLKEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 179 atevsvttamttmpknrtkeykivglysdgiNVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMP 258
Cdd:pfam00375 135 -------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAP 183
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 259 IGILFLIAGKIIEvEDWEIFRKLGLYMATVLSGLAIHSTVVLPLIYFIIVRKNPFRFALGMAQALLTALMISSSSATLPV 338
Cdd:pfam00375 184 IGVFALIANTVGT-YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPV 262
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 339 TFRCAEEKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGAAGVPQAGLVTM 418
Cdd:pfam00375 263 TLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVAL 342
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2025692012 419 VIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKL 464
Cdd:pfam00375 343 GLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
27-463 2.69e-43

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 159.16  E-value: 2.69e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  27 AVVLGIVIGVLVRGHSELSNLDKFYFAFP-GEILMRMLKLVILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFCTTII 104
Cdd:PRK11283   15 ALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITTV 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 105 AVILGIVLVVSIKPGVSQKVSEInrsgkspevSTVDamldlirnmfpenlvqacFQQYKTKREEVKPVSdpggnatEVSV 184
Cdd:PRK11283   95 AIILGITLANVFQPGAGIDMSQL---------ATVD------------------ISKYQSTTEEVQSHS-------HGLM 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 185 TTAMTTMPKNrtkeykIVGLYSDGiNVLGLIIFCLVFGLVIGKMGEK-GQILVDFFNALSDATMKIVQIIMCYMPIGILF 263
Cdd:PRK11283  141 GTILSLIPTN------IFASMAKG-EMLPIIFFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVGVFA 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 264 LIAgkiIEVEDWEIFRKLGLYMATVLSGLAI--HSTVVLPLIYFIIvRKNPFRFALGMAQALLTALMISSSSATLPvtfR 341
Cdd:PRK11283  214 LIA---VTVANFGFASLWPLAKLVLLVYFAIlfFALVVLGIVARLC-GLSIWILIRILKDELILAYSTASSETVLP---R 286
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 342 CAE--EKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGAAGVPQAGLVTMV 419
Cdd:PRK11283  287 IIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLL 366
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 2025692012 420 IVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 463
Cdd:PRK11283  367 ATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAK 410
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
28-463 1.17e-41

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 154.67  E-value: 1.17e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  28 VVLGIVIGVLVrGHselsnldkFYFAFP------GEILMRMLKLVILPLIISSMITGVAAL-DSNVSGKIGLRAVVYYFC 100
Cdd:PRK01663   13 VLVAIIIGILL-GH--------FYPELGaqmkplGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEI 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 101 TTIIAVILGIVLVVSIKPGVsqkvseinrsGKSPEVSTVDAmldlirnmfpenlvqacfqqyktkreevKPVSDPGGNAT 180
Cdd:PRK01663   84 VSTIALIIGLIVVNVVQPGA----------GMNIDPATLDA----------------------------KAVAQYAAQAH 125
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 181 EVSVTT-AMTTMPKNrtkeykIVGLYSDGiNVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPI 259
Cdd:PRK01663  126 EQGTVDfLMDIIPTT------VVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPI 198
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 260 GILFLIA--------GKIIevedweifrKLGLYMATVLSGLAIHSTVVLPLIY----FIIvrknpFRFALGMAQALLTAL 327
Cdd:PRK01663  199 GAFGAMAftigkygvGSLV---------QLGQLIGCFYITCILFVFVVLGAIArltgFSI-----FKFIRYIKEELLIVL 264
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 328 MISSSSATLPVTFRcAEEKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGA 407
Cdd:PRK01663  265 GTSSSESALPRMME-KMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGA 343
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2025692012 408 AGVPQAGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEK 463
Cdd:PRK01663  344 AGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVVVAK 400
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
12-461 7.33e-37

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 141.34  E-value: 7.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  12 RRFLRNnwLLLSTVAAVVLGIVIGVLVRGHSE-LSNLdkfyfafpGEILMRMLKLVILPLIISSMITGVA-ALDSNVSGK 89
Cdd:PRK13027    2 KKFLRS--LFGQVVIALVLGVALGAFFPHFAEsLKPL--------GDGFIKLIKMLIGPIVFCVVVSGIAgAGDLKKVGR 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012  90 IGLRAVVYYFCTTIIAVILGIVLVVSIKPGVsqkvseinrsGKSPEVSTVDAmldlirnmfpenlvqacfqqyktkreev 169
Cdd:PRK13027   72 VGLKAVIYFEVMTTIALVIGLVLAYLTGPGV----------GMNIDLRSLDA---------------------------- 113
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 170 KPVSDPGGNATEVSVTTA--MTTMPKNrtkeykIVGLYSDGiNVLGLIIFCLVFGLVIGKMGEKGQILVDFFNALSDATM 247
Cdd:PRK13027  114 ASLAGYAKNAQSLKGTAGflLKLIPTT------AVDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLF 186
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 248 KIVQIIMCYMPIGILFLIAgkiIEVEDWEI--FRKLGLYMATVLSGLAIHSTVVLPLIyfiiVRKNPFR-FAL--GMAQA 322
Cdd:PRK13027  187 RIMGFIIKLAPLGVLGAIA---FTTGKYGVgsLKQLGMLVAVFYLTCFVFVVVVLGAV----MRLAGFSvFKLirYLREE 259
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 323 LLTALMISSSSATLPVTFRcAEEKNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIITISITATA 402
Cdd:PRK13027  260 LLIVLGTASSDAVLPQVMR-KLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLV 338
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 403 ASIGAAGVPQAGLVTMVIVLSAVG-LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIV 461
Cdd:PRK13027  339 TSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
237-410 1.21e-11

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 66.43  E-value: 1.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 237 DFFNALSDATMKIVQIIMCYMPIGILFLIAGKIIEvEDWEIFRKLGLYMATVLSGLAIHSTVVLPLIYFIIVRKNPFRFA 316
Cdd:PRK13628  170 NVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAE-TGFSALAGYAQLLAVLVGCMLFVALVVNPLIVFWKIRRNPYPLV 248
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 317 LG-MAQALLTALMISSSSATLPVTFRCAEEKNqVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIIT 395
Cdd:PRK13628  249 FTcLRESGVTAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDLPTALL 327
                         170
                  ....*....|....*
gi 2025692012 396 ISITATAASIGAAGV 410
Cdd:PRK13628  328 LSVVAAISACGASGV 342
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
210-468 1.26e-11

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 65.84  E-value: 1.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 210 NVLGLIIFCLVFGLVigkMGEKGQILVDFFNALSDATMKIVQIIMCYMPIGILFLIAgKIIEVEDWEIFRKLGLYMATVL 289
Cdd:PRK14695   60 NYIGILSWAVIFGIA---MREASKNSKELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLANYGILLVLLV 135
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 290 SGLAIHSTVVLPLIYFIIVRKNPFRFALG-MAQALLTALMISSSSATLPVTFRCAEEKNqVDKRITRFVLPVGATINMDG 368
Cdd:PRK14695  136 TTMLFVAPVVNPLIAFFFMRRNPYPLVWNcLRVSGVTAFFTRSSATNIPVNMKLCHDLG-LNPDTYSVSIPLGSTINMAG 214
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 369 TALYEAVAAVFIAQLNDMDLSIGQIITISITATAASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLL----DR 444
Cdd:PRK14695  215 VAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqDS 294
                         250       260
                  ....*....|....*....|....
gi 2025692012 445 FRTMVNVLGDAFGTGIVEKLSKKE 468
Cdd:PRK14695  295 CETALNSSTDVLFTAVAEYAATRK 318
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
237-411 1.62e-11

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 65.96  E-value: 1.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 237 DFFNALSDATMKIVQIIMCYMPIGILFLIAGKIIEVeDWEIFRKLGLYMATVLSGLAIHSTVVLPLIYFIIVRKNPFRFA 316
Cdd:COG3633   169 TVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATT-GFSALLGYAHLLAVLVGCMLFVALVVNPLIVFLKIRRNPYPLV 247
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025692012 317 LG-MAQALLTALMISSSSATLPVTFRCAEEKNqVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDMDLSIGQIIT 395
Cdd:COG3633   248 FTcLRESGITAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEVDLPTALL 326
                         170
                  ....*....|....*.
gi 2025692012 396 ISITATAASIGAAGVP 411
Cdd:COG3633   327 LSVVAAVSACGASGVA 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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