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Conserved domains on  [gi|2024472865|ref|XP_040520940|]
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acidic amino acid decarboxylase GADL1 isoform X1 [Gallus gallus]

Protein Classification

pyridoxal phosphate-dependent decarboxylase family protein( domain architecture ID 10000562)

pyridoxal phosphate-dependent decarboxylase family protein is primarily involved in the biosynthesis of amino acids and amino acid-derived metabolites, but it is also found in the biosynthetic pathways of amino sugars and in the synthesis or catabolism of neurotransmitters

CATH:  3.40.640.10
EC:  4.1.1.-
Gene Ontology:  GO:0016830|GO:0030170|GO:0019752
PubMed:  8690703|7748903
SCOP:  4003328

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 46-510 5.64e-144

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


:

Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 421.55  E-value: 5.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865  46 IMEEIIQKADDVTEKVCEWrAPETLKKILDLEMRDTGESHQKLLQ-LCQDVIQYSVKTNHPRFFNQLYAGIDYYSLVARF 124
Cdd:COG0076     9 ALDLAADYLAGLDRPVFGP-SPEELRAALDEPLPEEGLPPEEALAeLEDLVLPGSVDWNHPRFLAFVTGGTTPAALAADL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 125 ITEALNPSVYTYEVSPVFLLVEEAVIKKMIEFIGW-EEGDGIFNPGGSVSNMYAMNLARYKFCPE-IKEKGLSGLPRLVL 202
Cdd:COG0076    88 LASALNQNMGDWDTSPAATELEREVVRWLADLLGLpEGAGGVFTSGGTEANLLALLAARDRALARrVRAEGLPGAPRPRI 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 203 FTSEECHYSMKKAASFLGIGTENVYFVKTDERGKMIPEELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICE 282
Cdd:COG0076   168 VVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPLAEIADIAR 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 283 KHDLWLHVDASWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKDnSGLLKKCYSAKAAYLFQQDkfyD 362
Cdd:COG0076   248 EHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRD-PELLREAFSFHASYLGPAD---D 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 363 VSYDTGDKSIQCSRRPDAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVCFWYIPPSLrkm 442
Cdd:COG0076   324 GVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNIVCFRYKPAGL--- 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024472865 443 edgPEFWQKLHRVApvvkERMMKKGSMMLGYQPNQGKVNfFRQVVISPQVSREDMDFLLDEIELLAKD 510
Cdd:COG0076   401 ---DEEDALNYALR----DRLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAAE 460
 
Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 46-510 5.64e-144

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 421.55  E-value: 5.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865  46 IMEEIIQKADDVTEKVCEWrAPETLKKILDLEMRDTGESHQKLLQ-LCQDVIQYSVKTNHPRFFNQLYAGIDYYSLVARF 124
Cdd:COG0076     9 ALDLAADYLAGLDRPVFGP-SPEELRAALDEPLPEEGLPPEEALAeLEDLVLPGSVDWNHPRFLAFVTGGTTPAALAADL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 125 ITEALNPSVYTYEVSPVFLLVEEAVIKKMIEFIGW-EEGDGIFNPGGSVSNMYAMNLARYKFCPE-IKEKGLSGLPRLVL 202
Cdd:COG0076    88 LASALNQNMGDWDTSPAATELEREVVRWLADLLGLpEGAGGVFTSGGTEANLLALLAARDRALARrVRAEGLPGAPRPRI 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 203 FTSEECHYSMKKAASFLGIGTENVYFVKTDERGKMIPEELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICE 282
Cdd:COG0076   168 VVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPLAEIADIAR 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 283 KHDLWLHVDASWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKDnSGLLKKCYSAKAAYLFQQDkfyD 362
Cdd:COG0076   248 EHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRD-PELLREAFSFHASYLGPAD---D 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 363 VSYDTGDKSIQCSRRPDAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVCFWYIPPSLrkm 442
Cdd:COG0076   324 GVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNIVCFRYKPAGL--- 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024472865 443 edgPEFWQKLHRVApvvkERMMKKGSMMLGYQPNQGKVNfFRQVVISPQVSREDMDFLLDEIELLAKD 510
Cdd:COG0076   401 ---DEEDALNYALR----DRLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAAE 460
DOPA_deC_like cd06450
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 107-505 3.48e-127

DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.


Pssm-ID: 99743 [Multi-domain]  Cd Length: 345  Bit Score: 374.23  E-value: 3.48e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 107 FFNQLYAGIDYYSLVARFITEALNPSVYTYEVSPVFLLVEEAVIKKMIEFIGW--EEGDGIFNPGGSVSNMYAMNLARYK 184
Cdd:cd06450     1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLpsEDADGVFTSGGSESNLLALLAARDR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 185 FCPEIKEKGLSGLPRLVLFTSEECHYSMKKAASFLGIgteNVYFVKTDERGKMIPEELEKQVQRARKEGSAPFLVCATAG 264
Cdd:cd06450    81 ARKRLKAGGGRGIDKLVIVCSDQAHVSVEKAAAYLDV---KVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVATAG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 265 TTVLGAFDPLDKIADICEKHDLWLHVDASWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKdnsgllk 344
Cdd:cd06450   158 TTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLVR------- 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 345 kcysakaaylfqqdkfydvsydtgdksiqcsrrpdAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLE 424
Cdd:cd06450   231 -----------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGFELLGE 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 425 PEYANVCFWYIPPSlrkmedgpefwqKLHRVAPVVKERMMKKGSMMLGYQPnQGKVNFFRQVVISPQVSREDMDFLLDEI 504
Cdd:cd06450   276 PNLSLVCFRLKPSV------------KLDELNYDLSDRLNERGGWHVPATT-LGGPNVLRFVVTNPLTTRDDADALLEDI 342


                  .
gi 2024472865 505 E 505
Cdd:cd06450   343 E 343
Pyridoxal_deC pfam00282
Pyridoxal-dependent decarboxylase conserved domain;
67-435 3.11e-126

Pyridoxal-dependent decarboxylase conserved domain;


Pssm-ID: 395219  Cd Length: 373  Bit Score: 372.91  E-value: 3.11e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865  67 PETLKKILDLEMRDTGESHQKLLQLCQDVIQYSVKTNH-PRFFNQLYAGIDYYSLVARFITEALNPSVYTYEVSPVFLLV 145
Cdd:pfam00282   1 PGYLKPLLPLAAPIIPEPELQIDGDIRRNLMPGVTTWHsPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 146 EEAVIKKMIEFIGW------EEGDGIFNPGGSVSNMYAMNLARYKFCPEIKEKG-----LSGLPRLVLFTSEECHYSMKK 214
Cdd:pfam00282  81 ENVVMNWLGEMLGLpaeflgQEGGGVLQPGSSESNLLALLAARTKWIKRMKAAGkpadsSGILAKLVAYTSDQAHSSIEK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 215 AASFLGIGtenVYFVKTDERGKMIPEELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICEKHDLWLHVDASW 294
Cdd:pfam00282 161 AALYGGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAY 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 295 GGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKDnSGLLKKCYSAKAAYLFQQDKfydvSYDTGDKSIQC 374
Cdd:pfam00282 238 GGSAFICPEFRHWLFGIERADSITFNPHKWMLVLLDCSAVWVKD-KEALQQAFQFNPLYLGHTDS----AYDTGHKQIPL 312

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024472865 375 SRRPDAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVCFWYI 435
Cdd:pfam00282 313 SRRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGRFEICAEVGLGLVCFRLK 373
PLN02590 PLN02590
probable tyrosine decarboxylase
 67-436 1.67e-42

probable tyrosine decarboxylase


Pssm-ID: 178200 [Multi-domain]  Cd Length: 539  Bit Score: 159.11  E-value: 1.67e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865  67 PETLKKILDLEMRDTGESHQKLLQ-LCQDVIQYSVKTNHPRFFnQLYAGidyYSLVARFITEALNPSV----YTYEVSPV 141
Cdd:PLN02590   92 PGYLRDMLPDSAPERPESLKELLDdVSKKIMPGITHWQSPSYF-AYYAS---STSVAGFLGEMLNAGLsvvgFTWLTSPA 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 142 FLLVEEAVIK---KMIE----FIGWEEGDGIFNPGGSVSNMYAMNLARYKFcpeIKEKGLSGLPRLVLFTSEECHYSMKK 214
Cdd:PLN02590  168 ATELEIIVLDwlaKLLQlpdhFLSTGNGGGVIQGTGCEAVLVVVLAARDRI---LKKVGKTLLPQLVVYGSDQTHSSFRK 244

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 215 AASFLGIGTENVYFVKTDERGK--MIPEELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICEKHDLWLHVDA 292
Cdd:PLN02590  245 ACLIGGIHEENIRLLKTDSSTNygMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDA 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 293 SWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKDNSGLLKKCYSAKAAYLFQQDKfYDVSYDTGDKSI 372
Cdd:PLN02590  325 AYAGNACICPEYRKFIDGIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEFKVSK-KDTVVNYKDWQI 403

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024472865 373 QCSRRPDAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVCFWYIP 436
Cdd:PLN02590  404 SLSRRFRSLKLWMVLRLYGSENLRNFIRDHVNLAKHFEDYVAQDPSFEVVTTRYFSLVCFRLAP 467
 
Name Accession Description Interval E-value
GadA COG0076
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ...
 46-510 5.64e-144

Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 439846 [Multi-domain]  Cd Length: 460  Bit Score: 421.55  E-value: 5.64e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865  46 IMEEIIQKADDVTEKVCEWrAPETLKKILDLEMRDTGESHQKLLQ-LCQDVIQYSVKTNHPRFFNQLYAGIDYYSLVARF 124
Cdd:COG0076     9 ALDLAADYLAGLDRPVFGP-SPEELRAALDEPLPEEGLPPEEALAeLEDLVLPGSVDWNHPRFLAFVTGGTTPAALAADL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 125 ITEALNPSVYTYEVSPVFLLVEEAVIKKMIEFIGW-EEGDGIFNPGGSVSNMYAMNLARYKFCPE-IKEKGLSGLPRLVL 202
Cdd:COG0076    88 LASALNQNMGDWDTSPAATELEREVVRWLADLLGLpEGAGGVFTSGGTEANLLALLAARDRALARrVRAEGLPGAPRPRI 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 203 FTSEECHYSMKKAASFLGIGTENVYFVKTDERGKMIPEELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICE 282
Cdd:COG0076   168 VVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPLAEIADIAR 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 283 KHDLWLHVDASWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKDnSGLLKKCYSAKAAYLFQQDkfyD 362
Cdd:COG0076   248 EHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRD-PELLREAFSFHASYLGPAD---D 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 363 VSYDTGDKSIQCSRRPDAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVCFWYIPPSLrkm 442
Cdd:COG0076   324 GVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELLAPPELNIVCFRYKPAGL--- 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024472865 443 edgPEFWQKLHRVApvvkERMMKKGSMMLGYQPNQGKVNfFRQVVISPQVSREDMDFLLDEIELLAKD 510
Cdd:COG0076   401 ---DEEDALNYALR----DRLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAAE 460
DOPA_deC_like cd06450
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 107-505 3.48e-127

DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.


Pssm-ID: 99743 [Multi-domain]  Cd Length: 345  Bit Score: 374.23  E-value: 3.48e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 107 FFNQLYAGIDYYSLVARFITEALNPSVYTYEVSPVFLLVEEAVIKKMIEFIGW--EEGDGIFNPGGSVSNMYAMNLARYK 184
Cdd:cd06450     1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLpsEDADGVFTSGGSESNLLALLAARDR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 185 FCPEIKEKGLSGLPRLVLFTSEECHYSMKKAASFLGIgteNVYFVKTDERGKMIPEELEKQVQRARKEGSAPFLVCATAG 264
Cdd:cd06450    81 ARKRLKAGGGRGIDKLVIVCSDQAHVSVEKAAAYLDV---KVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVATAG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 265 TTVLGAFDPLDKIADICEKHDLWLHVDASWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKdnsgllk 344
Cdd:cd06450   158 TTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLVR------- 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 345 kcysakaaylfqqdkfydvsydtgdksiqcsrrpdAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLE 424
Cdd:cd06450   231 -----------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGFELLGE 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 425 PEYANVCFWYIPPSlrkmedgpefwqKLHRVAPVVKERMMKKGSMMLGYQPnQGKVNFFRQVVISPQVSREDMDFLLDEI 504
Cdd:cd06450   276 PNLSLVCFRLKPSV------------KLDELNYDLSDRLNERGGWHVPATT-LGGPNVLRFVVTNPLTTRDDADALLEDI 342


                  .
gi 2024472865 505 E 505
Cdd:cd06450   343 E 343
Pyridoxal_deC pfam00282
Pyridoxal-dependent decarboxylase conserved domain;
67-435 3.11e-126

Pyridoxal-dependent decarboxylase conserved domain;


Pssm-ID: 395219  Cd Length: 373  Bit Score: 372.91  E-value: 3.11e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865  67 PETLKKILDLEMRDTGESHQKLLQLCQDVIQYSVKTNH-PRFFNQLYAGIDYYSLVARFITEALNPSVYTYEVSPVFLLV 145
Cdd:pfam00282   1 PGYLKPLLPLAAPIIPEPELQIDGDIRRNLMPGVTTWHsPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 146 EEAVIKKMIEFIGW------EEGDGIFNPGGSVSNMYAMNLARYKFCPEIKEKG-----LSGLPRLVLFTSEECHYSMKK 214
Cdd:pfam00282  81 ENVVMNWLGEMLGLpaeflgQEGGGVLQPGSSESNLLALLAARTKWIKRMKAAGkpadsSGILAKLVAYTSDQAHSSIEK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 215 AASFLGIGtenVYFVKTDERGKMIPEELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICEKHDLWLHVDASW 294
Cdd:pfam00282 161 AALYGGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAY 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 295 GGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKDnSGLLKKCYSAKAAYLFQQDKfydvSYDTGDKSIQC 374
Cdd:pfam00282 238 GGSAFICPEFRHWLFGIERADSITFNPHKWMLVLLDCSAVWVKD-KEALQQAFQFNPLYLGHTDS----AYDTGHKQIPL 312

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024472865 375 SRRPDAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVCFWYI 435
Cdd:pfam00282 313 SRRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGRFEICAEVGLGLVCFRLK 373
PLN02590 PLN02590
probable tyrosine decarboxylase
 67-436 1.67e-42

probable tyrosine decarboxylase


Pssm-ID: 178200 [Multi-domain]  Cd Length: 539  Bit Score: 159.11  E-value: 1.67e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865  67 PETLKKILDLEMRDTGESHQKLLQ-LCQDVIQYSVKTNHPRFFnQLYAGidyYSLVARFITEALNPSV----YTYEVSPV 141
Cdd:PLN02590   92 PGYLRDMLPDSAPERPESLKELLDdVSKKIMPGITHWQSPSYF-AYYAS---STSVAGFLGEMLNAGLsvvgFTWLTSPA 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 142 FLLVEEAVIK---KMIE----FIGWEEGDGIFNPGGSVSNMYAMNLARYKFcpeIKEKGLSGLPRLVLFTSEECHYSMKK 214
Cdd:PLN02590  168 ATELEIIVLDwlaKLLQlpdhFLSTGNGGGVIQGTGCEAVLVVVLAARDRI---LKKVGKTLLPQLVVYGSDQTHSSFRK 244

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 215 AASFLGIGTENVYFVKTDERGK--MIPEELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICEKHDLWLHVDA 292
Cdd:PLN02590  245 ACLIGGIHEENIRLLKTDSSTNygMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDA 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 293 SWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKDNSGLLKKCYSAKAAYLFQQDKfYDVSYDTGDKSI 372
Cdd:PLN02590  325 AYAGNACICPEYRKFIDGIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEFKVSK-KDTVVNYKDWQI 403

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024472865 373 QCSRRPDAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVCFWYIP 436
Cdd:PLN02590  404 SLSRRFRSLKLWMVLRLYGSENLRNFIRDHVNLAKHFEDYVAQDPSFEVVTTRYFSLVCFRLAP 467
PLN02880 PLN02880
tyrosine decarboxylase
 67-438 6.66e-41

tyrosine decarboxylase


Pssm-ID: 215475 [Multi-domain]  Cd Length: 490  Bit Score: 153.53  E-value: 6.66e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865  67 PETLKKILDLEMRDTGESHQKLLQLCQDVIQYSVKT-NHPRFFNqlyagidYY---SLVARFITEALNPSV----YTYEV 138
Cdd:PLN02880   44 PGYLRELLPDSAPNQPETLDQVLDDVQAKILPGVTHwQSPNYFA-------YYpsnSSVAGFLGEMLSAGLnivgFSWIT 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 139 SPVFLLVEEAVIK---KMI----EFIGWEEGDGIFNPGGSVSNMYAMNLARYKFcpeIKEKGLSGLPRLVLFTSEECHYS 211
Cdd:PLN02880  117 SPAATELEMIVLDwlaKLLnlpeQFLSTGNGGGVIQGTASEAVLVVLLAARDRV---LRKVGKNALEKLVVYASDQTHSA 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 212 MKKAASFLGIGTENVYFVKTDERGK--MIPEELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICEKHDLWLH 289
Cdd:PLN02880  194 LQKACQIAGIHPENCRLLKTDSSTNyaLAPELLSEAISTDLSSGLIPFFLCATVGTTSSTAVDPLLELGKIAKSNGMWFH 273

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 290 VDASWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVKDNSGLLKKcYSAKAAYLFQQDKFYDVSYDTGD 369
Cdd:PLN02880  274 VDAAYAGSACICPEYRHYIDGVEEADSFNMNAHKWFLTNFDCSLLWVKDRNALIQS-LSTNPEFLKNKASQANSVVDYKD 352

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024472865 370 KSIQCSRRPDAFKFWLMWKALGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVCFWYIPPS 438
Cdd:PLN02880  353 WQIPLGRRFRSLKLWMVLRLYGVENLQSYIRNHIKLAKEFEQLVAQDSRFEVVTPRIFSLVCFRLVPPK 421
PRK02769 PRK02769
histidine decarboxylase; Provisional
 118-504 1.40e-23

histidine decarboxylase; Provisional


Pssm-ID: 235068 [Multi-domain]  Cd Length: 380  Bit Score: 102.43  E-value: 1.40e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 118 YSLVARFITEALNPSVYTYEvSPVFLL----VEEAVIKKMIEF--IGWEEGDGIFNPGGSVSNMYAMNLARYKFcpeike 191
Cdd:PRK02769   36 YSALKRFFSFSINNCGDPYS-KSNYPLnsfdFERDVMNFFAELfkIPFNESWGYITNGGTEGNLYGCYLARELF------ 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 192 kglsglPRLVLFTSEECHYSMKKAASFLGIGTEnvyFVKTDERGKMIPEELEkqvQRARKEGSAPFLVCATAGTTVLGAF 271
Cdd:PRK02769  109 ------PDGTLYYSKDTHYSVSKIARLLRIKSR---VITSLPNGEIDYDDLI---SKIKENKNQPPIIFANIGTTMTGAI 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 272 DPLDKIADICEKH---DLWLHVDASWGGSALISRKHRRLL---HGIqraDSVAWNPHKMLLAGIQCCALLVKdnsgllKK 345
Cdd:PRK02769  177 DNIKEIQEILKKIgidDYYIHADAALSGMILPFVNNPPPFsfaDGI---DSIAISGHKFIGSPMPCGIVLAK------KK 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 346 cysakaaylfQQDKFY-DVSY-DTGDKSIQCSRrpDAFKFWLMWKA---LGTTGLEERVNRALALARYLVEEIKKReGFQ 420
Cdd:PRK02769  248 ----------YVERISvDVDYiGSRDQTISGSR--NGHTALLLWAAirsLGSKGLRQRVQHCLDMAQYAVDRLQAN-GIP 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 421 LLLEPEYANVCFwyippslrkmedgpefwqklhrvaPVVKERMMKKGSMmlgyqPNQGKVNffrQVVISPQVSREDMDFL 500
Cdd:PRK02769  315 AWRNPNSITVVF------------------------PCPSERIWKKWHL-----ATSGNQA---HIITMPHHNKQQIDSL 362


                  ....
gi 2024472865 501 LDEI 504
Cdd:PRK02769  363 IDEL 366
AAT_I cd01494
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ...
 146-327 6.84e-10

Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).


Pssm-ID: 99742 [Multi-domain]  Cd Length: 170  Bit Score: 58.16  E-value: 6.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 146 EEAVIKKMIEFIGWEEGDGIFNPGGSVSN-MYAMNLARYKfcpeikekglsglpRLVLFtSEECHYSmkKAASFLGIGTE 224
Cdd:cd01494     2 LEELEEKLARLLQPGNDKAVFVPSGTGANeAALLALLGPG--------------DEVIV-DANGHGS--RYWVAAELAGA 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 225 NVYFVKTDERGKMipeELEKQVQRARKEGSAPFLVCATAGTTVLGAFDPLDKIADICEKHDLWLHVDASWGGSALISRKH 304
Cdd:cd01494    65 KPVPVPVDDAGYG---GLDVAILEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGASPAPGV 141

                         170       180
                  ....*....|....*....|...
gi 2024472865 305 RRllhGIQRADSVAWNPHKMLLA 327
Cdd:cd01494   142 LI---PEGGADVVTFSLHKNLGG 161
PLN03032 PLN03032
serine decarboxylase; Provisional
 170-414 4.82e-07

serine decarboxylase; Provisional


Pssm-ID: 166673 [Multi-domain]  Cd Length: 374  Bit Score: 51.75  E-value: 4.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 170 GSVSNMYAMNLARYKFcpeikekglsglPRLVLFTSEECHYSMKKAASFLGIGTENvyfVKTDERGKMIPEELEKQVQRA 249
Cdd:PLN03032   94 GTEGNLHGILVGREVF------------PDGILYASRESHYSVFKAARMYRMEAVK---VPTLPSGEIDYDDLERALAKN 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 250 RKEgsaPFLVCATAGTTVLGAFDPLDKIADICEK-----HDLWLHVDASWGGSALISRKHRRLLHGIQRADSVAWNPHKM 324
Cdd:PLN03032  159 RDK---PAILNVNIGTTVKGAVDDLDRILRILKElgyteDRFYIHCDGALFGLMMPFVSRAPEVTFRKPIGSVSVSGHKF 235

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 325 LLAGIQCCALLVKdnsgllkkcysAKAAYLFQQDKFYDVSYDTgdkSIQCSRRPDAFKF-WLMWKALGTTGLEERVNRAL 403
Cdd:PLN03032  236 LGCPMPCGVALTR-----------KKHVKALSQNVEYLNSRDA---TIMGSRNGHAPLYlWYTLRRKGYRGIKRDVQHCM 301

                         250
                  ....*....|.
gi 2024472865 404 ALARYLVEEIK 414
Cdd:PLN03032  302 RNAHYLKDRLT 312
Aminotran_5 pfam00266
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ...
 144-431 8.14e-07

Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.


Pssm-ID: 425567 [Multi-domain]  Cd Length: 368  Bit Score: 51.09  E-value: 8.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 144 LVEEAViKKMIEFIGWEEGDGI-FNPGGSVS-NMYAMNLARykfcpEIKEKglsglpRLVLFTSEEcHYSMKKAASFLGI 221
Cdd:pfam00266  44 AYEEAR-EKVAEFINAPSNDEIiFTSGTTEAiNLVALSLGR-----SLKPG------DEIVITEME-HHANLVPWQELAK 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 222 -GTENVYFVKTDERGKMIPEELEKQV-QRARkegsapfLVCATAGTTVLGAFDPLDKIADICEKHDLWLHVDASwggSAL 299
Cdd:pfam00266 111 rTGARVRVLPLDEDGLLDLDELEKLItPKTK-------LVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVDAA---QAI 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 300 ISRKhrrllHGIQR--ADSVAWNPHKML-LAGIQccALLVKDNsgLLKKCysakAAYLFQQDKFYDVSYDTGDKSIQCSR 376
Cdd:pfam00266 181 GHRP-----IDVQKlgVDFLAFSGHKLYgPTGIG--VLYGRRD--LLEKM----PPLLGGGGMIETVSLQESTFADAPWK 247

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024472865 377 R----PDAFKFWLMWKA---LGTTGLEERVNRALALARYLVEEIKKREGFQLLLEPEYANVC 431
Cdd:pfam00266 248 FeagtPNIAGIIGLGAAleyLSEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPERRASII 309
PLN02263 PLN02263
serine decarboxylase
 197-432 1.56e-04

serine decarboxylase


Pssm-ID: 177904 [Multi-domain]  Cd Length: 470  Bit Score: 44.04  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 197 LPRLVLFTSEECHYSMKKAASFLGIGTENvyfVKTDERGKMIPEELEKQVQRARKEgsaPFLVCATAGTTVLGAFDPLDK 276
Cdd:PLN02263  176 FPDGILYASRESHYSVFKAARMYRMECVK---VDTLVSGEIDCADFKAKLLANKDK---PAIINVNIGTTVKGAVDDLDL 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 277 IADICEK----HD-LWLHVDASWGGSALISRKHRRLLHGIQRADSVAWNPHKMLLAGIQCCALLVK-DNSGLLKKcysak 350
Cdd:PLN02263  250 VIKTLEEcgfsQDrFYIHCDGALFGLMMPFVKRAPKVTFKKPIGSVSVSGHKFVGCPMPCGVQITRmEHINVLSS----- 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 351 aaylfqqdkfyDVSY-DTGDKSIQCSRRPDAFKF-WLMWKALGTTGLEERVNRALALARYLVEEIKKrEGFQLLLEPEYA 428
Cdd:PLN02263  325 -----------NVEYlASRDATIMGSRNGHAPIFlWYTLNRKGYRGFQKEVQKCLRNAHYLKDRLRE-AGISAMLNELSS 392


                  ....
gi 2024472865 429 NVCF 432
Cdd:PLN02263  393 TVVF 396
CsdA COG0520
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
228-325 1.62e-04

Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];


Pssm-ID: 440286 [Multi-domain]  Cd Length: 396  Bit Score: 43.97  E-value: 1.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 228 FVKTDERGKMIPEELEKQVQRARKegsapfLVCATAGTTVLGAFDPLDKIADICEKHDLWLHVDA--SWGgsalisrkHR 305
Cdd:COG0520   133 VIPLDEDGELDLEALEALLTPRTK------LVAVTHVSNVTGTVNPVKEIAALAHAHGALVLVDGaqSVP--------HL 198

                          90       100
                  ....*....|....*....|.
gi 2024472865 306 RL-LHGIQrADSVAWNPHKML 325
Cdd:COG0520   199 PVdVQALG-CDFYAFSGHKLY 218
Orn_deC_like cd00615
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 274-340 7.40e-03

Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.


Pssm-ID: 99739 [Multi-domain]  Cd Length: 294  Bit Score: 38.38  E-value: 7.40e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024472865 274 LDKIADICEKHDLWLHVDASWGGSALISRKHRR--LLHGiqrADSVAWNPHKMLLAGIQCCALLVKDNS 340
Cdd:cd00615   172 LRKIVEEAHHRGLPVLVDEAHGAHFRFHPILPSsaAMAG---ADIVVQSTHKTLPALTQGSMIHVKGDL 237
PRK06939 PRK06939
2-amino-3-ketobutyrate coenzyme A ligase; Provisional
 240-293 8.19e-03

2-amino-3-ketobutyrate coenzyme A ligase; Provisional


Pssm-ID: 235893 [Multi-domain]  Cd Length: 397  Bit Score: 38.64  E-value: 8.19e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024472865 240 EELEKQVQRARKEGsAPFLVCATAGttVL---GAFDPLDKIADICEKHDLWLHVDAS 293
Cdd:PRK06939  159 ADLEAQLKEAKEAG-ARHKLIATDG--VFsmdGDIAPLPEICDLADKYDALVMVDDS 212
Beta_elim_lyase pfam01212
Beta-eliminating lyase;
229-292 8.42e-03

Beta-eliminating lyase;


Pssm-ID: 426128 [Multi-domain]  Cd Length: 288  Bit Score: 38.35  E-value: 8.42e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024472865 229 VKTDERGKMIPEELEKQVQRARKEGSAPF-LVCAT-----AGTTVLgAFDPLDKIADICEKHDLWLHVDA 292
Cdd:pfam01212 101 LDGDEAGNMDLEDLEAAIREVGADIFPPTgLISLEnthnsAGGQVV-SLENLREIAALAREHGIPVHLDG 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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