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Conserved domains on  [gi|2024440217|ref|XP_040514292|]
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NEDD4-binding protein 2-like 2 isoform X8 [Gallus gallus]

Protein Classification

ATP-binding protein( domain architecture ID 12153064)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain may function as an ATPase; similar to NEDD4-binding protein 2-like 1/2 (N4BP2L1 and N4BP2L2), whose functions are not clear

Gene Ontology:  GO:0005524
PubMed:  15037234|18208389

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 457-589 2.63e-23

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


:

Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 97.00  E-value: 2.63e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKSTLSRFLLDhSRDGIVLSTDDYFRQ------QDGYTYNAAqLGDAHDWNQKRAKQAMEQGKsPVIIDN 530
Cdd:pfam13671    1 LILLVGLPGSGKSTLARRLLE-ELGAVRLSSDDERKRlfgegrPSISYYTDA-TDRTYERLHELARIALRAGR-PVILDA 77

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024440217  531 TNTQAWEMKPYVEVALEKGYRVEFREPDTwwkfDPEELEKRNK---------HGVTREKIAQMLERYE 589
Cdd:pfam13671   78 TNLRRDERARLLALAREYGVPVRIVVFEA----PEEVLRERLAararaggdpSDVPEEVLDRQKARFE 141
 
Name Accession Description Interval E-value
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 457-589 2.63e-23

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 97.00  E-value: 2.63e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKSTLSRFLLDhSRDGIVLSTDDYFRQ------QDGYTYNAAqLGDAHDWNQKRAKQAMEQGKsPVIIDN 530
Cdd:pfam13671    1 LILLVGLPGSGKSTLARRLLE-ELGAVRLSSDDERKRlfgegrPSISYYTDA-TDRTYERLHELARIALRAGR-PVILDA 77

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024440217  531 TNTQAWEMKPYVEVALEKGYRVEFREPDTwwkfDPEELEKRNK---------HGVTREKIAQMLERYE 589
Cdd:pfam13671   78 TNLRRDERARLLALAREYGVPVRIVVFEA----PEEVLRERLAararaggdpSDVPEEVLDRQKARFE 141
COG4639 COG4639
Predicted kinase [General function prediction only];
457-589 1.41e-21

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 92.20  E-value: 1.41e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKSTLSRfllDHSRDGIVLSTDDyFRQQ--DGYTYNAAQlGDAHDWNQKRAKQAMEQGKsPVIIDNTNTQ 534
Cdd:COG4639      4 LVVLIGLPGSGKSTFAR---RLFAPTEVVSSDD-IRALlgGDENDQSAW-GDVFQLAHEIARARLRAGR-LTVVDATNLQ 77

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  535 AWEMKPYVEVALEKGYRVEFrepdtWWkFDP--EELEKRNK---HGVTREKIAQMLERYE 589
Cdd:COG4639     78 REARRRLLALARAYGALVVA-----VV-LDVplEVCLARNAardRQVPEEVIRRMLRRLR 131
pseT PHA02530
polynucleotide kinase; Provisional
 457-573 6.36e-10

polynucleotide kinase; Provisional


Pssm-ID: 222856 [Multi-domain]  Cd Length: 300  Bit Score: 61.58  E-value: 6.36e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKSTLSRFLLDHSRDGIVLSTDDYfRQQ-------DGYTYNAAQLGDAHDWNQKRAKQAMEQGKSpVIID 529
Cdd:PHA02530     4 IILTVGVPGSGKSTWAREFAAKNPKAVNVNRDDL-RQSlfghgewGEYKFTKEKEDLVTKAQEAAALAALKSGKS-VIIS 81

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 2024440217  530 NTNTQAWEMKPYVEVALEKGyrVEFREPDtwwkFDP--EELEKRNK 573
Cdd:PHA02530    82 DTNLNPERRRKWKELAKELG--AEFEEKV----FDVpvEELVKRNR 121
PNK-3'Pase TIGR01663
polynucleotide 5'-kinase 3'-phosphatase; This model represents the metazoan 5 ...
 446-549 3.17e-04

polynucleotide 5'-kinase 3'-phosphatase; This model represents the metazoan 5'-polynucleotide-kinase-3'-phosphatase, PNKP, which is believed to be involved in repair of oxidative DNA damage. Removal of 3' phosphates is essential for the further processing of the break by DNA polymerases. The central phosphatase domain is a member of the IIIA subfamily (TIGR01662) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. As is common in this superfamily, the enzyme is magnesium dependent. A difference between this enzyme and other HAD-superfamily phosphatases is in the third conserved catalytic motif which usually contains two conserved aspartate residues believed to be involved in binding the magnesium ion. Here, the second aspartate is replaced by a conserved arginine residue which may indicate an interaction with the phosphate backbone of the substrate. Very close relatives of this domain are also found separate from the N- and C-terminal domains seen here, as in the 3'-phosphatase found in plants. The larger family of these domains is described by TIGR01664. Outside of the phosphatase domain is a P-loop ATP-binding motif associated with the kinase activity. The entry for the mouse homolog appears to be missing a large piece of sequence corresponding to the first conserved catalytic motif of the phosphatase domain as well as the conserved threonine of the second motif. Either this is a sequencing artifact or this may represent a pseudo- or non-functional gene. Note that the EC number for the kinase function is: 2.7.1.78


Pssm-ID: 130724 [Multi-domain]  Cd Length: 526  Bit Score: 44.63  E-value: 3.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  446 PEERS-DCSQKVLLILRGLPGSGKST-LSRFLldhsrdgivlstddyfrQQDGYTY-NAAQLGDahdWNQ--KRAKQAME 520
Cdd:TIGR01663  359 PDDLAlDDAPCEMVIAVGFPGAGKSHfCKKFF-----------------QPAGYKHvNADTLGS---TQNclTACERALD 418

                           90       100
                   ....*....|....*....|....*....
gi 2024440217  521 QGKSpVIIDNTNTQAWEMKPYVEVALEKG 549
Cdd:TIGR01663  419 QGKR-CAIDNTNPDAASRAKFLQCARAAG 446
 
Name Accession Description Interval E-value
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 457-589 2.63e-23

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 97.00  E-value: 2.63e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKSTLSRFLLDhSRDGIVLSTDDYFRQ------QDGYTYNAAqLGDAHDWNQKRAKQAMEQGKsPVIIDN 530
Cdd:pfam13671    1 LILLVGLPGSGKSTLARRLLE-ELGAVRLSSDDERKRlfgegrPSISYYTDA-TDRTYERLHELARIALRAGR-PVILDA 77

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024440217  531 TNTQAWEMKPYVEVALEKGYRVEFREPDTwwkfDPEELEKRNK---------HGVTREKIAQMLERYE 589
Cdd:pfam13671   78 TNLRRDERARLLALAREYGVPVRIVVFEA----PEEVLRERLAararaggdpSDVPEEVLDRQKARFE 141
COG4639 COG4639
Predicted kinase [General function prediction only];
457-589 1.41e-21

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 92.20  E-value: 1.41e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKSTLSRfllDHSRDGIVLSTDDyFRQQ--DGYTYNAAQlGDAHDWNQKRAKQAMEQGKsPVIIDNTNTQ 534
Cdd:COG4639      4 LVVLIGLPGSGKSTFAR---RLFAPTEVVSSDD-IRALlgGDENDQSAW-GDVFQLAHEIARARLRAGR-LTVVDATNLQ 77

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  535 AWEMKPYVEVALEKGYRVEFrepdtWWkFDP--EELEKRNK---HGVTREKIAQMLERYE 589
Cdd:COG4639     78 REARRRLLALARAYGALVVA-----VV-LDVplEVCLARNAardRQVPEEVIRRMLRRLR 131
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
457-589 3.40e-12

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 65.70  E-value: 3.40e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKSTLSRFLLDHsRDGIVLSTD--------------DYFRQQDGYTYNAAqlgdahdwnQKRAKQAMEQG 522
Cdd:COG0645      1 LILVCGLPGSGKSTLARALAER-LGAVRLRSDvvrkrlfgaglaplERSPEATARTYARL---------LALARELLAAG 70

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024440217  523 KSpVIIDNTNTQAWEMKPYVEVALEKGYRVEFREPDTwwkfDPEE----LEKRNKHG----VTREKIAQMLERYE 589
Cdd:COG0645     71 RS-VILDATFLRRAQREAFRALAEEAGAPFVLIWLDA----PEEVlrerLEARNAEGgdsdATWEVLERQLAFEE 140
pseT PHA02530
polynucleotide kinase; Provisional
 457-573 6.36e-10

polynucleotide kinase; Provisional


Pssm-ID: 222856 [Multi-domain]  Cd Length: 300  Bit Score: 61.58  E-value: 6.36e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKSTLSRFLLDHSRDGIVLSTDDYfRQQ-------DGYTYNAAQLGDAHDWNQKRAKQAMEQGKSpVIID 529
Cdd:PHA02530     4 IILTVGVPGSGKSTWAREFAAKNPKAVNVNRDDL-RQSlfghgewGEYKFTKEKEDLVTKAQEAAALAALKSGKS-VIIS 81

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 2024440217  530 NTNTQAWEMKPYVEVALEKGyrVEFREPDtwwkFDP--EELEKRNK 573
Cdd:PHA02530    82 DTNLNPERRRKWKELAKELG--AEFEEKV----FDVpvEELVKRNR 121
KTI12 pfam08433
Chromatin associated protein KTI12; This is a family of chromatin associated proteins which ...
 457-613 1.98e-07

Chromatin associated protein KTI12; This is a family of chromatin associated proteins which interact with the Elongator complex, a component of the elongating form of RNA polymerase II. The Elongator complex has histone acetyltransferase activity.


Pssm-ID: 400643  Cd Length: 269  Bit Score: 53.84  E-value: 1.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  457 LLILRGLPGSGKST----LSRFLLDHSRDGIVLSTDDYFRQQDGYTyNAAQLGDAHDWNQKRAKQAMEQGKSpVIIDNTN 532
Cdd:pfam08433    1 LVLLTGLPSSGKSTrakqLAKYLEESNYDVIVISDESLGIEKDDYK-DSAKEKFLRGSLRSAVKRDLSKNTI-VIVDSLN 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  533 tqawemkpYVevaleKGYRVEF----REPDT-----WWKFDPEELEKRN-----KHGVTREKIAQMLERYE--------- 589
Cdd:pfam08433   79 --------YI-----KGFRYELyciaKAARTtycviHCKAPLDLCRKWNeergqKSRYPDELLDALIQRYEepnsknrwd 145

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2024440217  590 --------YQISIP-------IVMNSELPPHKHTQRPPL 613
Cdd:pfam08433  146 splftvlsDDETLPldeiwkaLIEKQPLPPNQATQLKPL 184
Kti12 COG4088
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ...
 456-536 7.58e-07

tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];


Pssm-ID: 443264 [Multi-domain]  Cd Length: 179  Bit Score: 50.50  E-value: 7.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  456 VLLILRGLPGSGKST----LSRFLLDHSRDGIVLSTDDY--FRQQDGYTYNAA-QLgdAHDWNQKRAKQAMEQGKSpVII 528
Cdd:COG4088      5 MLLILTGPPGSGKTTfakaLAQRLYAEGIAVALLHSDDFrrFLVNESFPKETYeEV--VEDVRTTTADNALDNGYS-VIV 81


                   ....*...
gi 2024440217  529 DNTNTQAW 536
Cdd:COG4088     82 DGTFYYRS 89
Zeta_toxin pfam06414
Zeta toxin; This family consists of several bacterial zeta toxin proteins. Zeta toxin is ...
 454-555 5.54e-06

Zeta toxin; This family consists of several bacterial zeta toxin proteins. Zeta toxin is thought to be part of a postregulational killing system in bacteria. It relies on antitoxin/toxin systems that secure stable inheritance of low and medium copy number plasmids during cell division and kill cells that have lost the plasmid.


Pssm-ID: 428926  Cd Length: 192  Bit Score: 48.13  E-value: 5.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  454 QKVLLILRGLPGSGKSTLSRFLLDHS---RDGIVLSTDDY---------FRQQDGYTYNAAQLGDAHDWNQKRAKQAMEQ 521
Cdd:pfam06414   10 RPKAILLGGQPGAGKTELARALLDELgrqGNVVRIDPDDFrelhphyreLQAADPKTASEYTQPDASRWVEKLLQHAIEN 89

                           90       100       110
                   ....*....|....*....|....*....|....
gi 2024440217  522 GKSpVIIDNTNTQAWEMKPYVEVALEKGYRVEFR 555
Cdd:pfam06414   90 GYN-IILEGTLRSPDVAKKIARALKAAGYRVEVA 122
PNK-3'Pase TIGR01663
polynucleotide 5'-kinase 3'-phosphatase; This model represents the metazoan 5 ...
 446-549 3.17e-04

polynucleotide 5'-kinase 3'-phosphatase; This model represents the metazoan 5'-polynucleotide-kinase-3'-phosphatase, PNKP, which is believed to be involved in repair of oxidative DNA damage. Removal of 3' phosphates is essential for the further processing of the break by DNA polymerases. The central phosphatase domain is a member of the IIIA subfamily (TIGR01662) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. As is common in this superfamily, the enzyme is magnesium dependent. A difference between this enzyme and other HAD-superfamily phosphatases is in the third conserved catalytic motif which usually contains two conserved aspartate residues believed to be involved in binding the magnesium ion. Here, the second aspartate is replaced by a conserved arginine residue which may indicate an interaction with the phosphate backbone of the substrate. Very close relatives of this domain are also found separate from the N- and C-terminal domains seen here, as in the 3'-phosphatase found in plants. The larger family of these domains is described by TIGR01664. Outside of the phosphatase domain is a P-loop ATP-binding motif associated with the kinase activity. The entry for the mouse homolog appears to be missing a large piece of sequence corresponding to the first conserved catalytic motif of the phosphatase domain as well as the conserved threonine of the second motif. Either this is a sequencing artifact or this may represent a pseudo- or non-functional gene. Note that the EC number for the kinase function is: 2.7.1.78


Pssm-ID: 130724 [Multi-domain]  Cd Length: 526  Bit Score: 44.63  E-value: 3.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  446 PEERS-DCSQKVLLILRGLPGSGKST-LSRFLldhsrdgivlstddyfrQQDGYTY-NAAQLGDahdWNQ--KRAKQAME 520
Cdd:TIGR01663  359 PDDLAlDDAPCEMVIAVGFPGAGKSHfCKKFF-----------------QPAGYKHvNADTLGS---TQNclTACERALD 418

                           90       100
                   ....*....|....*....|....*....
gi 2024440217  521 QGKSpVIIDNTNTQAWEMKPYVEVALEKG 549
Cdd:TIGR01663  419 QGKR-CAIDNTNPDAASRAKFLQCARAAG 446
AAA_18 pfam13238
AAA domain;
459-586 6.54e-04

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 40.87  E-value: 6.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  459 ILRGLPGSGKSTLSRFLLDHSRDGIVLStdDYFRQQDGYTYNAAQLGDAH---DWNQKRAKQAMEQ-----GKSPVIIDN 530
Cdd:pfam13238    2 LITGTPGVGKTTLAKELSKRLGFGDNVR--DLALENGLVLGDDPETRESKrldEDKLDRLLDLLEEnaaleEGGNLIIDG 79

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024440217  531 TNTQ--AWEMKPYVEVALekgyRVefrepdtwwkfDPEELEKRNKH-GVTREKIAQMLE 586
Cdd:pfam13238   80 HLAElePERAKDLVGIVL----RA-----------SPEELLERLEKrGYEEAKIKENEE 123
AAA_28 pfam13521
AAA domain;
455-594 2.22e-03

AAA domain;


Pssm-ID: 433278 [Multi-domain]  Cd Length: 164  Bit Score: 39.94  E-value: 2.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  455 KVLLIlrGLPGSGKSTLSRFLldHSRDGIVLSTD---DYFRQQDGYTYNAAQLGDAHDWNQK-----RAKQAMEQGKSPV 526
Cdd:pfam13521    1 RIVIT--GGPSTGKTTLAEAL--AARFGYPVVPEaarEILEELGADGGDALPWVEDLLAFARgvleaQLEDEAAAAANDL 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  527 IIDNTN---TQAW-------EMKPYVEVALEKGY-RVEFREPDTWWKFD---PEELEKRNKhgvTREKIAQMLERYEYQI 592
Cdd:pfam13521   77 LFFDRGpldTLAYsrayggpCPPELEAAARASRYdLVFLLPPDPEIVQDgerREDPEERER---FHERLREALRELGIPV 153


                   ..
gi 2024440217  593 SI 594
Cdd:pfam13521  154 II 155
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 458-523 3.05e-03

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 40.50  E-value: 3.05e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  458 LILRGLPGSGKSTLSRFLldHSRDGIV-LSTDDYFRQqdgytyNAAQ---LGdahdwnqKRAKQAMEQGK 523
Cdd:COG0563      3 IILLGPPGAGKGTQAKRL--AEKYGIPhISTGDMLRA------AVKAgteLG-------KKAKEYMDAGE 57
COG4185 COG4185
Predicted ABC-type ATPase or kinase [General function prediction only];
453-589 3.10e-03

Predicted ABC-type ATPase or kinase [General function prediction only];


Pssm-ID: 443339  Cd Length: 197  Bit Score: 40.26  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024440217  453 SQKVLLILRGLPGSGKSTLSRFLLDH-SRDGIVLSTDDYFRQQDGYTYNAAQLgDAHDWNQKRAKQAMEQGKS------- 524
Cdd:COG4185      2 AMPRLYIIAGPNGAGKSTFARTILPEeLGGLEFVNADLIARGLSPFNPETAAY-EAGRLALERREELLAAGRSfafettl 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024440217  525 --PVIIDntntqawemkpYVEVALEKGYRVEFrepdtW--WKFDPEELEKRNK-------HGVTREKIaqmLERYE 589
Cdd:COG4185     81 sgPSKLD-----------LIREAKAAGYRVRL-----IfvGLDSPELAIARVAqrvaeggHDVPEDKI---RRRYP 137
ADK pfam00406
Adenylate kinase;
460-523 6.31e-03

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 39.21  E-value: 6.31e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024440217  460 LRGLPGSGKSTLSRFLLDHSrdGIV-LSTDDYFRQQdgyTYNAAQLGdahdwnqKRAKQAMEQGK 523
Cdd:pfam00406    1 LLGPPGAGKGTQAEKIVQKY--GLPhLSTGDLLRAE---IKSGTELG-------KEAKEYMDKGE 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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