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Conserved domains on  [gi|1958759819|ref|XP_038960185|]
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G-protein-signaling modulator 1 isoform X1 [Rattus norvegicus]

Protein Classification

TPR and TPR_12 domain-containing protein( domain architecture ID 11421204)

protein containing domains TPR, TPR_12, and GoLoco

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
69-322 1.53e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.67  E-value: 1.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  69 YSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARA 148
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 149 LYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTF 228
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 229 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEY 308
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1958759819 309 HLRHLVIAQELADR 322
Cdd:COG0457   207 LRKKLAILTLAALA 220
GoLoco pfam02188
GoLoco motif;
494-515 1.07e-07

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 48.19  E-value: 1.07e-07
                          10        20
                  ....*....|....*....|..
gi 1958759819 494 ECFFDLLSKFQSSRMDDQRCPL 515
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
547-567 7.96e-06

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.79  E-value: 7.96e-06
                          10        20
                  ....*....|....*....|.
gi 1958759819 547 EEFFDLIASSQSRRLDDQRAS 567
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
TPR_12 pfam13424
Tetratricopeptide repeat;
290-358 4.44e-04

Tetratricopeptide repeat;


:

Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 4.44e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958759819 290 YSLGNTYTLLQDYERAAEYHLRHLVIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQE 358
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
69-322 1.53e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.67  E-value: 1.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  69 YSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARA 148
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 149 LYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTF 228
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 229 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEY 308
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1958759819 309 HLRHLVIAQELADR 322
Cdd:COG0457   207 LRKKLAILTLAALA 220
TPR_12 pfam13424
Tetratricopeptide repeat;
207-278 4.99e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.16  E-value: 4.99e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958759819 207 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEF--GDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQ 278
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco pfam02188
GoLoco motif;
494-515 1.07e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 48.19  E-value: 1.07e-07
                          10        20
                  ....*....|....*....|..
gi 1958759819 494 ECFFDLLSKFQSSRMDDQRCPL 515
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
547-567 7.96e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.79  E-value: 7.96e-06
                          10        20
                  ....*....|....*....|.
gi 1958759819 547 EEFFDLIASSQSRRLDDQRAS 567
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 493-515 9.13e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 42.49  E-value: 9.13e-06
                           10        20
                   ....*....|....*....|...
gi 1958759819  493 EECFFDLLSKFQSSRMDDQRCPL 515
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 546-568 1.83e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.72  E-value: 1.83e-05
                           10        20
                   ....*....|....*....|...
gi 1958759819  546 TEEFFDLIASSQSRRLDDQRASV 568
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 40-431 2.41e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 44.52  E-value: 2.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  40 KAGDFKAGVAFFEAAVQV-----GTEDLKTLSAiYSQLGNAYFYLKEYARALQfhkhdllLARTIGDRMGEAK------- 107
Cdd:NF040586  404 LRGDYESARDLAERALERwrerlGPDDRQTLRL-RFHLANALRSLGRYEEARE-------LDEDTLERQRRVLglgedhp 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 108 ----ASGNLGNTLKVLGRFDEAivccqrhLDIAQEqgdkvgearalynignvyhakgkqlSWNAAQDPghLPPDVRETLh 183
Cdd:NF040586  476 htlmTAGGLGADLRALGRFREA-------LELDEE-------------------------TLERHRRV--FGEDHPRTL- 520

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 184 rasefyernlslvkelgdraaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFG--DKAAERRAYSNLGNAHIFLGR 261
Cdd:NF040586  521 -----------------------RAANNLAVSLRLLGDYREALELDREVLRRRRRVLgpDHPRTLLSANNLARDLRELGR 577

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 262 FDVAAEHYKKTLQLSRQLR---DQAVEAQACYSLGNTYTLLQDYERAAEYHLRhlvIAQELADRVGEG----RAC-WSLG 333
Cdd:NF040586  578 YAEALDLLEEALERYREVLggpDHPDTLRAAKSLAVALRRAGRLEEALELAED---TYERYRRRFGPDhpdtLAAaLSLA 654

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 334 NAYVSMGSPAQALTFAKKHLQISQEigdRNGE-----LTARMNIAHLQLALGRltsPAAAEkpdlagyeaqgarpkrtqR 408
Cdd:NF040586  655 NDLRALGDADEARELAREVLDRYRR---VLGEdhpftLACRNNLAVLLRALGD---PEEAR------------------E 710

                         410       420
                  ....*....|....*....|...
gi 1958759819 409 LSAETWDLLrlpldREQNGETHH 431
Cdd:NF040586  711 LAEAALEGL-----RERLGPDHP 728
TPR_12 pfam13424
Tetratricopeptide repeat;
290-358 4.44e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 4.44e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958759819 290 YSLGNTYTLLQDYERAAEYHLRHLVIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQE 358
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 106-138 6.98e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 6.98e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1958759819  106 AKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQE 138
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
69-322 1.53e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.67  E-value: 1.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  69 YSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARA 148
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 149 LYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTF 228
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 229 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEY 308
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1958759819 309 HLRHLVIAQELADR 322
Cdd:COG0457   207 LRKKLAILTLAALA 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
105-389 1.94e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.28  E-value: 1.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 105 EAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEqgdkvgEARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHR 184
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPD------DAEALYNLGLAYLRLGR--------------------YEE 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 185 ASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDV 264
Cdd:COG0457    61 ALADYEQALEL------DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGRYDE 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 265 AAEHYKKTLQLSRQLrdqaveAQACYSLGNTYTLLQDYERAAEYHLRHLviAQELADRVGEGRACWSLGNAYVSMGSPAQ 344
Cdd:COG0457   129 AIEAYERALELDPDD------ADALYNLGIALEKLGRYEEALELLEKLE--AAALAALLAAALGEAALALAAAEVLLALL 200

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1958759819 345 ALTFAKKHLQISQEIGDRNGELTARMNIAHLQLALGRLTSPAAAE 389
Cdd:COG0457   201 LALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
145-424 3.23e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.81  E-value: 3.23e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 145 EARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLVKELGDraaqgrAYGNLGNTHYLLGNFTE 224
Cdd:COG0457     7 DAEAYNNLGLAYRRLGR--------------------YEEAIEDYEKALELDPDDAE------ALYNLGLAYLRLGRYEE 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 225 ATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLrdqaveAQACYSLGNTYTLLQDYER 304
Cdd:COG0457    61 ALADYEQALELDPDDAE------ALNNLGLALQALGRYEEALEDYDKALELDPDD------AEALYNLGLALLELGRYDE 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 305 AAEYHLRHLVIAQELADrvgegrACWSLGNAYVSMGSPAQALTFAKKHLQisQEIGDRNGELTARMNIAHLQLALGRLTS 384
Cdd:COG0457   129 AIEAYERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEA--AALAALLAAALGEAALALAAAEVLLALL 200

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1958759819 385 PAAAEKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLDRE 424
Cdd:COG0457   201 LALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 33-354 5.94e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.45  E-value: 5.94e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  33 LEGERLCKAGDFKAGVAFFEAAVQVGTEDLKTlsaiYSQLGNAYFYLKEYARALQFHKHdlLLARTiGDRmgeAKASGNL 112
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEA----HLALGNLYRRRGEYDRAIRIHQK--LLERD-PDR---AEALLEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 113 GNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERn 192
Cdd:COG2956    83 AQDYLKAGLLDRAEELLEKLLELDPDD------AEALRLLAEIYEQEGD--------------------WEKAIEVLER- 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 193 lsLVKELGDRAaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFgdkaaeRRAYSNLGNAHIFLGRFDVAAEHYKKT 272
Cdd:COG2956   136 --LLKLGPENA---HAYCELAELYLEQGDYDEAIEALEKALKLDPDC------ARALLLLAELYLEQGDYEEAIAALERA 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 273 LQLSRQLrdqaveAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADRVgegracwSLGNAYVSMGSPAQALTFAKKH 352
Cdd:COG2956   205 LEQDPDY------LPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL-------ALADLLERKEGLEAALALLERQ 271


                  ..
gi 1958759819 353 LQ 354
Cdd:COG2956   272 LR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 2-285 3.07e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.01  E-value: 3.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819   2 ASPAPPAAEELPGPAARRLYSRMEASCLELALEGERLCKAGDFKAGVAFFEAAvqvgtEDLKTLSAIYSQLGNAYFYLKE 81
Cdd:COG3914    19 AAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAA-----AALLLLAALLELAALLLQALGR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  82 YARALQFHKHDLLLARTigdrmgEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGK 161
Cdd:COG3914    94 YEEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDF------AEAYLNLGEALRRLGR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 162 qlswnaaqdpghlppdvretLHRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFgd 241
Cdd:COG3914   162 --------------------LEEAIAALRRALEL------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN-- 213

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1958759819 242 kaaeRRAYSNLgnahIFLGRFDVAAEHYKKTLQLSRQLRDQAVE 285
Cdd:COG3914   214 ----ADAHSNL----LFALRQACDWEVYDRFEELLAALARGPSE 249
TPR_12 pfam13424
Tetratricopeptide repeat;
207-278 4.99e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.16  E-value: 4.99e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958759819 207 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEF--GDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQ 278
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 184-382 1.00e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 1.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 184 RASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFD 263
Cdd:COG3914    16 ALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 264 VAAEHYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADrvgegrACWSLGNAYVSMGSPA 343
Cdd:COG3914    96 EALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE------AYLNLGEALRRLGRLE 163

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1958759819 344 QALTFAKKHLQIsqeigdRNGELTARMNIAHLQLALGRL 382
Cdd:COG3914   164 EAIAALRRALEL------DPDNAEALNNLGNALQDLGRL 196
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 111-382 1.09e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.66  E-value: 1.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 111 NLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYE 190
Cdd:COG2956    47 ALGNLYRRRGEYDRAIRIHQKLLERDPDR------AEALLELAQDYLKAGL--------------------LDRAEELLE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 191 RnlsLVKELGDRAaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEfgdkaaERRAYSNLGNAHIFLGRFDVAAEHYK 270
Cdd:COG2956   101 K---LLELDPDDA---EALRLLAEIYEQEGDWEKAIEVLERLLKLGPE------NAHAYCELAELYLEQGDYDEAIEALE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 271 KTLQLSRQlrdqAVEAQacYSLGNTYTLLQDYERAAEyHLRHLVIAQELADRVGEgracwSLGNAYVSMGSPAQALTFAK 350
Cdd:COG2956   169 KALKLDPD----CARAL--LLLAELYLEQGDYEEAIA-ALERALEQDPDYLPALP-----RLAELYEKLGDPEEALELLR 236

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1958759819 351 KHLQisqeigdRNGELTARMNIAHLQLALGRL 382
Cdd:COG2956   237 KALE-------LDPSDDLLLALADLLERKEGL 261
COG3899 COG3899
Predicted ATPase [General function prediction only];
122-424 6.43e-08

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 56.02  E-value: 6.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  122 FDEAIVCCQRHLDIAQEQGDKVGEARALYNIGNVYHAKGKqlswnaaqdpghlPPDVRETLHRASEFYERNLSLVKELGD 201
Cdd:COG3899    721 YAEALRYLERALELLPPDPEEEYRLALLLELAEALYLAGR-------------FEEAEALLERALAARALAALAALRHGN 787

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  202 RAAQGRAYGNLGntHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRD 281
Cdd:COG3899    788 PPASARAYANLG--LLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGD 865

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  282 QAVEAQACYSLGNTyTLLQDYERAAEYHLRHLVIAQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQEIGD 361
Cdd:COG3899    866 AALALLALAAAAAA-AAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAA 944

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958759819  362 RNGELTARMNIAHLQLALGRLTSPAAAEKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLDRE 424
Cdd:COG3899    945 LAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAA 1007
GoLoco pfam02188
GoLoco motif;
494-515 1.07e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 48.19  E-value: 1.07e-07
                          10        20
                  ....*....|....*....|..
gi 1958759819 494 ECFFDLLSKFQSSRMDDQRCPL 515
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 203-358 1.46e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.96  E-value: 1.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 203 AAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQlrdq 282
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPE------AFALLGEILLQLGDLDEAIVLLHEALELDPD---- 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958759819 283 avEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADrvgegrACWSLGNAYVSMGSPAQALTFAKKHLQISQE 358
Cdd:COG4783    71 --EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE------AYLRLARAYRALGRPDEAIAALEKALELDPD 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
35-161 4.11e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.85  E-value: 4.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  35 GERLCKAGDFKAGVAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEYARALQfhkhdlLLARTIGDRMGEAKASGNLGN 114
Cdd:COG0457    49 GLAYLRLGRYEEALADYEQALELDPDD----AEALNNLGLALQALGRYEEALE------DYDKALELDPDDAEALYNLGL 118

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1958759819 115 TLKVLGRFDEAIVCCQRHLDIaqeqgdKVGEARALYNIGNVYHAKGK 161
Cdd:COG0457   119 ALLELGRYDEAIEAYERALEL------DPDDADALYNLGIALEKLGR 159
TPR_12 pfam13424
Tetratricopeptide repeat;
247-318 5.67e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 44.69  E-value: 5.67e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958759819 247 RAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLR--DQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQE 318
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLLgpDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco pfam02188
GoLoco motif;
547-567 7.96e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.79  E-value: 7.96e-06
                          10        20
                  ....*....|....*....|.
gi 1958759819 547 EEFFDLIASSQSRRLDDQRAS 567
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 493-515 9.13e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 42.49  E-value: 9.13e-06
                           10        20
                   ....*....|....*....|...
gi 1958759819  493 EECFFDLLSKFQSSRMDDQRCPL 515
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR_12 pfam13424
Tetratricopeptide repeat;
106-162 1.54e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.53  E-value: 1.54e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958759819 106 AKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQ--GDKVGEARALYNIGNVYHAKGKQ 162
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRY 61
COG3899 COG3899
Predicted ATPase [General function prediction only];
174-418 1.58e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 48.32  E-value: 1.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  174 LPPDVRETLH-RASEFYERNLSLVKEL------------GDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFG 240
Cdd:COG3899    660 LPPEERRALHrRIARALEARGPEPLEErlfelahhlnraGERDRAARLLLRAARRALARGAYAEALRYLERALELLPPDP 739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  241 DKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYT-----LLQDYERAAEYHLRHLVI 315
Cdd:COG3899    740 EEEYRLALLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYAnlgllLLGDYEEAYEFGELALAL 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  316 AQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQEIGDRNGELTARMNIAHLQLALGRLTSPAAAEKPDLAG 395
Cdd:COG3899    820 AERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAA 899

                          250       260
                   ....*....|....*....|...
gi 1958759819  396 YEAQGARPKRTQRLSAETWDLLR 418
Cdd:COG3899    900 AAAALAAAAAAAALAAAELARLA 922
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 546-568 1.83e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.72  E-value: 1.83e-05
                           10        20
                   ....*....|....*....|...
gi 1958759819  546 TEEFFDLIASSQSRRLDDQRASV 568
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR_12 pfam13424
Tetratricopeptide repeat;
146-238 7.24e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 7.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 146 ARALYNIGNVYHAKGKqlswnaaqdpghlppdvretLHRASEFYERNLSLVKEL--GDRAAQGRAYGNLGNTHYLLGNFT 223
Cdd:pfam13424   3 ATALNNLAAVLRRLGR--------------------YDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYE 62

                          90
                  ....*....|....*
gi 1958759819 224 EATTFHKERLAIAKE 238
Cdd:pfam13424  63 EALELLERALALAEK 77
TPR_12 pfam13424
Tetratricopeptide repeat;
65-138 1.01e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 1.01e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958759819  65 LSAIYSQLGNAYFYLKEYARALQFHKHDLLLARTI--GDRMGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQE 138
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 243-382 1.20e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 243 AAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYhlrhlvIAQELADR 322
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPD------NPEAFALLGEILLQLGDLDEAIVL------LHEALELD 68

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 323 VGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQEIGDrngeltARMNIAHLQLALGRL 382
Cdd:COG4783    69 PDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE------AYLRLARAYRALGRP 122
COG3899 COG3899
Predicted ATPase [General function prediction only];
29-480 1.59e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 45.23  E-value: 1.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819   29 LELALE-GERLCKAGDFKAGVAFFEAAVQVGT-------EDLKTLSAIYSQLGNAYFYLKEYARALQFHKHDLLLARTIG 100
Cdd:COG3899    745 LALLLElAEALYLAGRFEEAEALLERALAARAlaalaalRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLG 824

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  101 DRMGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQGDKVGEARALYnignvyhakgkQLSWNAAQDPGHLPPDVRE 180
Cdd:COG3899    825 DRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALA-----------AAAAAAAAAAALAAAAAAA 893

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  181 TLHRASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLG 260
Cdd:COG3899    894 ARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALA 973

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  261 RFDVAAEHY---KKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADRVGEGRACWSLGNAYV 337
Cdd:COG3899    974 AAAAAAAAAaaaAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAA 1053

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  338 SMGSPAQALTFAKKHLQISQEIGDRNGELTARMNIAHLQLALGRLTSPAAAEKPDLAGYEAQGARPKRTQRLSAETWDLL 417
Cdd:COG3899   1054 AAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAA 1133

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958759819  418 RLPLDREQNGETHHTGDWRGPSRDSLPLPMRSRKYQEGPDAIERRPREGSHSPLDSADVRVQV 480
Cdd:COG3899   1134 ALLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALL 1196
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 30-161 1.94e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 1.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  30 ELALEGERLCKAGDFKAGVAFFEAAVQVGTEDLktlsAIYSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKAS 109
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALELDPDNP----EAFALLGEILLQLGDLDEAIVLLHEALELDP------DEPEAR 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958759819 110 GNLGNTLKVLGRFDEAIVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGK 161
Cdd:COG4783    76 LNLGLALLKAGDYDEALALLEKALKLDPEH------PEAYLRLARAYRALGR 121
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 40-431 2.41e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 44.52  E-value: 2.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  40 KAGDFKAGVAFFEAAVQV-----GTEDLKTLSAiYSQLGNAYFYLKEYARALQfhkhdllLARTIGDRMGEAK------- 107
Cdd:NF040586  404 LRGDYESARDLAERALERwrerlGPDDRQTLRL-RFHLANALRSLGRYEEARE-------LDEDTLERQRRVLglgedhp 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 108 ----ASGNLGNTLKVLGRFDEAivccqrhLDIAQEqgdkvgearalynignvyhakgkqlSWNAAQDPghLPPDVRETLh 183
Cdd:NF040586  476 htlmTAGGLGADLRALGRFREA-------LELDEE-------------------------TLERHRRV--FGEDHPRTL- 520

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 184 rasefyernlslvkelgdraaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFG--DKAAERRAYSNLGNAHIFLGR 261
Cdd:NF040586  521 -----------------------RAANNLAVSLRLLGDYREALELDREVLRRRRRVLgpDHPRTLLSANNLARDLRELGR 577

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 262 FDVAAEHYKKTLQLSRQLR---DQAVEAQACYSLGNTYTLLQDYERAAEYHLRhlvIAQELADRVGEG----RAC-WSLG 333
Cdd:NF040586  578 YAEALDLLEEALERYREVLggpDHPDTLRAAKSLAVALRRAGRLEEALELAED---TYERYRRRFGPDhpdtLAAaLSLA 654

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 334 NAYVSMGSPAQALTFAKKHLQISQEigdRNGE-----LTARMNIAHLQLALGRltsPAAAEkpdlagyeaqgarpkrtqR 408
Cdd:NF040586  655 NDLRALGDADEARELAREVLDRYRR---VLGEdhpftLACRNNLAVLLRALGD---PEEAR------------------E 710

                         410       420
                  ....*....|....*....|...
gi 1958759819 409 LSAETWDLLrlpldREQNGETHH 431
Cdd:NF040586  711 LAEAALEGL-----RERLGPDHP 728
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 199-316 2.98e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.87  E-value: 2.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 199 LGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQ 278
Cdd:COG5010    47 RDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE------LYYNLALLYSRSGDKDEAKEYYEKALALSPD 120

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1958759819 279 lrdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLVIA 316
Cdd:COG5010   121 ------NPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
TPR_7 pfam13176
Tetratricopeptide repeat;
288-322 2.98e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 38.68  E-value: 2.98e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1958759819 288 ACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADR 322
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDR 35
TPR_12 pfam13424
Tetratricopeptide repeat;
290-358 4.44e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 4.44e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958759819 290 YSLGNTYTLLQDYERAAEYHLRHLVIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQE 358
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_1 pfam00515
Tetratricopeptide repeat;
106-138 5.29e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.79  E-value: 5.29e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1958759819 106 AKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQE 138
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
145-328 6.28e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.82  E-value: 6.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 145 EARALYNIGNVYHAKGKqlsWNAAqdpghlppdvRETLHRAsefyernLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTE 224
Cdd:COG4785    72 LAQLYYERGVAYDSLGD---YDLA----------IADFDQA-------LEL------DPDLAEAYNNRGLAYLLLGDYDA 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 225 ATtfhkERLAIAKEFGDKAAErrAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYslgntytLLQDYER 304
Cdd:COG4785   126 AL----EDFDRALELDPDYAY--AYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAE-------RKLDPEK 192

                         170       180
                  ....*....|....*....|....
gi 1958759819 305 AAEYHLRHLVIAQELADRVGEGRA 328
Cdd:COG4785   193 ALALLLEDWATAYLLQGDTEEARE 216
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 106-138 6.98e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 6.98e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1958759819  106 AKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQE 138
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
247-275 1.35e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.63  E-value: 1.35e-03
                          10        20
                  ....*....|....*....|....*....
gi 1958759819 247 RAYSNLGNAHIFLGRFDVAAEHYKKTLQL 275
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALEL 30
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
184-281 1.42e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 184 RASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKerlAIAKEFGDKaaerRAYSNLGNAHIFLGRFD 263
Cdd:COG3063    10 EAEEYYEKALEL------DPDNADALNNLGLLLLEQGRYDEAIALEK---ALKLDPNNA----EALLNLAELLLELGDYD 76

                          90
                  ....*....|....*...
gi 1958759819 264 VAAEHYKKTLQLSRQLRD 281
Cdd:COG3063    77 EALAYLERALELDPSALR 94
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 247-356 1.42e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.22  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 247 RAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQEladrvgEG 326
Cdd:COG4235    18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPD------NADALLDLAEALLAAGDTEEAEELLERALALDPD------NP 85

                          90       100       110
                  ....*....|....*....|....*....|
gi 1958759819 327 RACWSLGNAYVSMGSPAQALTFAKKHLQIS 356
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
35-205 2.11e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.38  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  35 GERLCKAGDFKAGVAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEYARALQFHKHDLLLARtigdrmGEAKASGNLGN 114
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALELDPDD----AEALYNLGLALLELGRYDEAIEAYERALELDP------DDADALYNLGI 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 115 TLKVLGRFDEAIVCCQRHLDIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAAQDPGHLPPDVRETLHRASEFYERNLS 194
Cdd:COG0457   153 ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232

                         170
                  ....*....|.
gi 1958759819 195 LVKELGDRAAQ 205
Cdd:COG0457   233 LRLAALALYQY 243
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 195-308 2.34e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 2.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 195 LVKELGDRAAQ----GRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEHYK 270
Cdd:COG4235     2 AIARLRQALAAnpndAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNAD------ALLDLAEALLAAGDTEEAEELLE 75

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1958759819 271 KTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEY 308
Cdd:COG4235    76 RALALDPD------NPEALYLLGLAAFQQGDYAEAIAA 107
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
255-358 2.97e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 2.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 255 AHIFLGRFDVAAEHYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHlRHLVIAQELADrvgegrACWSLGN 334
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPD------NADALNNLGLLLLEQGRYDEAIALE-KALKLDPNNAE------ALLNLAE 67

                          90       100
                  ....*....|....*....|....
gi 1958759819 335 AYVSMGSPAQALTFAKKHLQISQE 358
Cdd:COG3063    68 LLLELGDYDEALAYLERALELDPS 91
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
216-308 4.57e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.07  E-value: 4.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 216 HYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDvAAEHYKKTLQLSRQlrdqavEAQACYSLGNT 295
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNAD------ALNNLGLLLLEQGRYD-EAIALEKALKLDPN------NAEALLNLAEL 68

                          90
                  ....*....|...
gi 1958759819 296 YTLLQDYERAAEY 308
Cdd:COG3063    69 LLELGDYDEALAY 81
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 220-382 5.12e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 39.60  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 220 GNFTEATTFHKERLAIAKEfgDKAAER-RAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTl 298
Cdd:pfam17874  15 GDAERALELAEQALALLPE--DDLLARgLATFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTLWALLQQGEILR- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 299 LQDYERAAEYHLRHlviAQELADRVGE------GRACWSLGNAYVSMGSPAQALTFAKKHLQISQEiGDRNGELTARMNI 372
Cdd:pfam17874  92 AQGRLHQALETYQQ---ALQLARDHGLqhlplhGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQ-WEPDAAVDAYVLL 167

                         170
                  ....*....|
gi 1958759819 373 AHLQLALGRL 382
Cdd:pfam17874 168 ARIALAQGEL 177
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 255-351 5.60e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 5.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 255 AHIFLGRFDVAAEHYKktlQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRhlvIAQELADRVGEGRACWSLGN 334
Cdd:COG1729     2 ALLKAGDYDEAIAAFK---AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGL 75

                          90
                  ....*....|....*..
gi 1958759819 335 AYVSMGSPAQALTFAKK 351
Cdd:COG1729    76 SYLELGDYDKARATLEE 92
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 194-274 6.93e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.89  E-value: 6.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819 194 SLVKELGDRAAQGRAYGNLGNTHYLLGNFTEA-TTFhkerLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKT 272
Cdd:COG1729    18 AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAaEAF----EKLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATLEEL 93


                  ..
gi 1958759819 273 LQ 274
Cdd:COG1729    94 IK 95
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
40-138 8.12e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.30  E-value: 8.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759819  40 KAGDFKAGVAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEYARALQFHKhdlllARTIGDRMGEAKAsgNLGNTLKVL 119
Cdd:COG3063     4 KLGDLEEAEEYYEKALELDPDN----ADALNNLGLLLLEQGRYDEAIALEK-----ALKLDPNNAEALL--NLAELLLEL 72

                          90
                  ....*....|....*....
gi 1958759819 120 GRFDEAIVCCQRHLDIAQE 138
Cdd:COG3063    73 GDYDEALAYLERALELDPS 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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