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Conserved domains on  [gi|1958759707|ref|XP_038960137|]
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solute carrier family 12 member 5 isoform X5 [Rattus norvegicus]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
1-1072 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1309.31  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707    1 MALFEEEMDTSPMVSSLLSGLANYTNLPQGSKEHEEAENNEGGKKKPV-QAPRMGTFMGVYLPCLQNIFGVILFLRLTWV 79
Cdd:TIGR00930   25 RPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPaGAVKFGWVMGVLVPCLLNIWGVILFLRLSWI 104
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707   80 VGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEIL 159
Cdd:TIGR00930  105 VGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETV 184
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  160 LAylfpamaIFKaEDASGEAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPN 239
Cdd:TIGR00930  185 LD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPA 256
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  240 FPICLLGNRTLSRHgfdvcaklawegnetvttrlwglfcssrllnatcdeyftrnnvtEIQGIPGAASGlikenlwssyl 319
Cdd:TIGR00930  257 KGFFGLGNEIFSEN--------------------------------------------FIPGIPGPEGG----------- 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  320 tkgviverrgmpsvgladgtpvdmdhpyvfsdmtsyFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTS 399
Cdd:TIGR00930  282 ------------------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTT 325
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  400 AVYISSVVLFGACIEGVVLRDKFGEAVN---------------------GNLVVGTLAWPSPWVIVIGSFFSTCGAGLQS 458
Cdd:TIGR00930  326 VVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALAS 405
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  459 LTGAPRLLQAISRDGIVPFLQVFGHGKA-NGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTL 537
Cdd:TIGR00930  406 LVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASL 485
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  538 LRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLE 617
Cdd:TIGR00930  486 LRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLE 565
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  618 EGPPHTKNWRPQLLVLVRVDqdqnVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGF 697
Cdd:TIGR00930  566 EVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAF 641
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  698 CQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQkEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNP--- 774
Cdd:TIGR00930  642 YAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqv 720
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  775 -----------------------------------ERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQ 819
Cdd:TIGR00930  721 qeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQ 800
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  820 MDDNSIQMKKDLTTFLYHLRITAEVEVVEMhesDISAytYEKTLVMEQRSQILKQMHLTKNEREREIqsitdesrgsirr 899
Cdd:TIGR00930  801 KDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA------------- 862
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  900 knpantrlrlnvpeetacdneekpeeevqlihdqsapscpssspspgeepegegeTDPekvHLTWTKDKSAAQKNkgpsp 979
Cdd:TIGR00930  863 -------------------------------------------------------KDP---KMTWTKPWKITDAE----- 879
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  980 vssegikdffsmkpewenlNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDENYMEFLEVLTEQLDRVML 1059
Cdd:TIGR00930  880 -------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLL 940
                         1130
                   ....*....|...
gi 1958759707 1060 VRGGGREVITIYS 1072
Cdd:TIGR00930  941 VRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
1-1072 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1309.31  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707    1 MALFEEEMDTSPMVSSLLSGLANYTNLPQGSKEHEEAENNEGGKKKPV-QAPRMGTFMGVYLPCLQNIFGVILFLRLTWV 79
Cdd:TIGR00930   25 RPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPaGAVKFGWVMGVLVPCLLNIWGVILFLRLSWI 104
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707   80 VGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEIL 159
Cdd:TIGR00930  105 VGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETV 184
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  160 LAylfpamaIFKaEDASGEAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPN 239
Cdd:TIGR00930  185 LD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPA 256
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  240 FPICLLGNRTLSRHgfdvcaklawegnetvttrlwglfcssrllnatcdeyftrnnvtEIQGIPGAASGlikenlwssyl 319
Cdd:TIGR00930  257 KGFFGLGNEIFSEN--------------------------------------------FIPGIPGPEGG----------- 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  320 tkgviverrgmpsvgladgtpvdmdhpyvfsdmtsyFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTS 399
Cdd:TIGR00930  282 ------------------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTT 325
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  400 AVYISSVVLFGACIEGVVLRDKFGEAVN---------------------GNLVVGTLAWPSPWVIVIGSFFSTCGAGLQS 458
Cdd:TIGR00930  326 VVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALAS 405
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  459 LTGAPRLLQAISRDGIVPFLQVFGHGKA-NGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTL 537
Cdd:TIGR00930  406 LVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASL 485
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  538 LRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLE 617
Cdd:TIGR00930  486 LRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLE 565
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  618 EGPPHTKNWRPQLLVLVRVDqdqnVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGF 697
Cdd:TIGR00930  566 EVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAF 641
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  698 CQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQkEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNP--- 774
Cdd:TIGR00930  642 YAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqv 720
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  775 -----------------------------------ERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQ 819
Cdd:TIGR00930  721 qeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQ 800
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  820 MDDNSIQMKKDLTTFLYHLRITAEVEVVEMhesDISAytYEKTLVMEQRSQILKQMHLTKNEREREIqsitdesrgsirr 899
Cdd:TIGR00930  801 KDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA------------- 862
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  900 knpantrlrlnvpeetacdneekpeeevqlihdqsapscpssspspgeepegegeTDPekvHLTWTKDKSAAQKNkgpsp 979
Cdd:TIGR00930  863 -------------------------------------------------------KDP---KMTWTKPWKITDAE----- 879
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  980 vssegikdffsmkpewenlNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDENYMEFLEVLTEQLDRVML 1059
Cdd:TIGR00930  880 -------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLL 940
                         1130
                   ....*....|...
gi 1958759707 1060 VRGGGREVITIYS 1072
Cdd:TIGR00930  941 VRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
58-631 7.94e-44

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 166.34  E-value: 7.94e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707   58 GVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVpAGGSYYMISRSLGPEFGGAVG 137
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  138 LcFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEdasgeaaamlnnmrVYGTCVLTCMATVVFVGVKYVNKFALVFLG 217
Cdd:pfam00324   80 W-NYWLSWITVLALELTAASILIQFWELVPDIPYLW--------------VWGAVFLVLLTIINLVGVKWYGEAEFWFAL 144
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  218 CVILSILAIYAGVIksafdppnfpicllgnrtlsrhgfdvcaklawegnetvttrlwGLFCSSRLLNATCDEYFTRNnvt 297
Cdd:pfam00324  145 IKIIAIIGFIIVGI-------------------------------------------ILLSGGNPNDGAIFRYLGDN--- 178
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  298 eiqgipgaasgLIKENLwSSYLTKGVIverrgmpsvgladgtpvdmdhpYVFSdmtsyftllvgIYFPSVTGIMAGSNRS 377
Cdd:pfam00324  179 -----------GGKNNF-PPGFGKGFI----------------------SVFV-----------IAFFAFTGIELVGIAA 213
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  378 GDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVV------GTLAWPSpwVIVIGSFFST 451
Cdd:pfam00324  214 GEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASPFViffkflGISGLAP--LINAVILTAA 291
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  452 CGAGLQSLTGAPRLLQAISRDGIVPFlqVFGHGKANGEPTWALLLTACICEIGILIASLdeVAPILSMFFLMCYMFVNLA 531
Cdd:pfam00324  292 LSAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGLI 367
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  532 CAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARY 611
Cdd:pfam00324  368 VWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLL 447
                          570       580
                   ....*....|....*....|
gi 1958759707  612 ALLRLEEGPPHTKNWRPQLL 631
Cdd:pfam00324  448 FLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
66-591 1.28e-31

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 129.25  E-value: 1.28e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707   66 NIFGVILFLRLTWVVGIAG--IMESFCMVFICCsctMLTAISMSAIATNgvVP-AGGSYYMISRSLGPEFGGAVGLCFYL 142
Cdd:COG0531     25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  143 GTTFAGAMYILGTIEiLLAYLFPAMAIFkaedasgeaaamlnnmrVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILS 222
Cdd:COG0531    100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  223 ILAIYAGVIkSAFDPPNFpicllgnrtlsrHGFDvcaklawegneTVTTRLWGLFcssrllnatcdeyftrnnvteiqgi 302
Cdd:COG0531    162 LLLFIVVGL-FAFDPANF------------TPFL-----------PAGGGLSGVL------------------------- 192
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  303 pgAASGLIkenlwssyltkgviverrgmpsvgladgtpvdmdhpyvfsdmtsyftllvgiyFPSVTGIMAGSNRSGDLRD 382
Cdd:COG0531    193 --AALALA-----------------------------------------------------FFAFTGFEAIANLAEEAKN 217
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  383 AQKSIPTGTILAIATTSAVYISSVVLFGacieGVVLRDKFGEAVNGNLVVGTLAWPSP--WVIVIGSFFSTCGAGLQSLT 460
Cdd:COG0531    218 PKRNIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASIL 293
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  461 GAPRLLQAISRDGIVPflQVFGH-GKANGEPTWALLLTACICEIGILI--ASLDEVAPILSMFFLMCYMFVNLACAVQtL 537
Cdd:COG0531    294 GASRLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAVIVL-R 370
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958759707  538 LRTPNWRPRFRYYHWTLSFLGMSLCLALMFIC---SWYYALVAMLIAGLIYKYIEYR 591
Cdd:COG0531    371 RRRPDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
1-1072 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1309.31  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707    1 MALFEEEMDTSPMVSSLLSGLANYTNLPQGSKEHEEAENNEGGKKKPV-QAPRMGTFMGVYLPCLQNIFGVILFLRLTWV 79
Cdd:TIGR00930   25 RPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPaGAVKFGWVMGVLVPCLLNIWGVILFLRLSWI 104
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707   80 VGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEIL 159
Cdd:TIGR00930  105 VGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETV 184
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  160 LAylfpamaIFKaEDASGEAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPN 239
Cdd:TIGR00930  185 LD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFDKPA 256
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  240 FPICLLGNRTLSRHgfdvcaklawegnetvttrlwglfcssrllnatcdeyftrnnvtEIQGIPGAASGlikenlwssyl 319
Cdd:TIGR00930  257 KGFFGLGNEIFSEN--------------------------------------------FIPGIPGPEGG----------- 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  320 tkgviverrgmpsvgladgtpvdmdhpyvfsdmtsyFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTS 399
Cdd:TIGR00930  282 ------------------------------------FFSLFGIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTT 325
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  400 AVYISSVVLFGACIEGVVLRDKFGEAVN---------------------GNLVVGTLAWPSPWVIVIGSFFSTCGAGLQS 458
Cdd:TIGR00930  326 VVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLVSPFPPLITAGIFSATLSSALAS 405
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  459 LTGAPRLLQAISRDGIVPFLQVFGHGKA-NGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTL 537
Cdd:TIGR00930  406 LVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASL 485
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  538 LRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLE 617
Cdd:TIGR00930  486 LRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLE 565
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  618 EGPPHTKNWRPQLLVLVRVDqdqnVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGF 697
Cdd:TIGR00930  566 EVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAF 641
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  698 CQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQkEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNP--- 774
Cdd:TIGR00930  642 YAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLPISVlqv 720
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  775 -----------------------------------ERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQ 819
Cdd:TIGR00930  721 qeelendcsedsielndgkistqpdmhleastqfqKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQ 800
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  820 MDDNSIQMKKDLTTFLYHLRITAEVEVVEMhesDISAytYEKTLVMEQRSQILKQMHLTKNEREREIqsitdesrgsirr 899
Cdd:TIGR00930  801 KDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRLHKTEKDREA------------- 862
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  900 knpantrlrlnvpeetacdneekpeeevqlihdqsapscpssspspgeepegegeTDPekvHLTWTKDKSAAQKNkgpsp 979
Cdd:TIGR00930  863 -------------------------------------------------------KDP---KMTWTKPWKITDAE----- 879
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  980 vssegikdffsmkpewenlNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDENYMEFLEVLTEQLDRVML 1059
Cdd:TIGR00930  880 -------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLL 940
                         1130
                   ....*....|...
gi 1958759707 1060 VRGGGREVITIYS 1072
Cdd:TIGR00930  941 VRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
58-631 7.94e-44

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 166.34  E-value: 7.94e-44
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707   58 GVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVpAGGSYYMISRSLGPEFGGAVG 137
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  138 LcFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEdasgeaaamlnnmrVYGTCVLTCMATVVFVGVKYVNKFALVFLG 217
Cdd:pfam00324   80 W-NYWLSWITVLALELTAASILIQFWELVPDIPYLW--------------VWGAVFLVLLTIINLVGVKWYGEAEFWFAL 144
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  218 CVILSILAIYAGVIksafdppnfpicllgnrtlsrhgfdvcaklawegnetvttrlwGLFCSSRLLNATCDEYFTRNnvt 297
Cdd:pfam00324  145 IKIIAIIGFIIVGI-------------------------------------------ILLSGGNPNDGAIFRYLGDN--- 178
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  298 eiqgipgaasgLIKENLwSSYLTKGVIverrgmpsvgladgtpvdmdhpYVFSdmtsyftllvgIYFPSVTGIMAGSNRS 377
Cdd:pfam00324  179 -----------GGKNNF-PPGFGKGFI----------------------SVFV-----------IAFFAFTGIELVGIAA 213
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  378 GDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVV------GTLAWPSpwVIVIGSFFST 451
Cdd:pfam00324  214 GEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASPFViffkflGISGLAP--LINAVILTAA 291
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  452 CGAGLQSLTGAPRLLQAISRDGIVPFlqVFGHGKANGEPTWALLLTACICEIGILIASLdeVAPILSMFFLMCYMFVNLA 531
Cdd:pfam00324  292 LSAANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGLI 367
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  532 CAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARY 611
Cdd:pfam00324  368 VWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLL 447
                          570       580
                   ....*....|....*....|
gi 1958759707  612 ALLRLEEGPPHTKNWRPQLL 631
Cdd:pfam00324  448 FLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
66-591 1.28e-31

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 129.25  E-value: 1.28e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707   66 NIFGVILFLRLTWVVGIAG--IMESFCMVFICCsctMLTAISMSAIATNgvVP-AGGSYYMISRSLGPEFGGAVGLCFYL 142
Cdd:COG0531     25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  143 GTTFAGAMYILGTIEiLLAYLFPAMAIFkaedasgeaaamlnnmrVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILS 222
Cdd:COG0531    100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  223 ILAIYAGVIkSAFDPPNFpicllgnrtlsrHGFDvcaklawegneTVTTRLWGLFcssrllnatcdeyftrnnvteiqgi 302
Cdd:COG0531    162 LLLFIVVGL-FAFDPANF------------TPFL-----------PAGGGLSGVL------------------------- 192
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  303 pgAASGLIkenlwssyltkgviverrgmpsvgladgtpvdmdhpyvfsdmtsyftllvgiyFPSVTGIMAGSNRSGDLRD 382
Cdd:COG0531    193 --AALALA-----------------------------------------------------FFAFTGFEAIANLAEEAKN 217
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  383 AQKSIPTGTILAIATTSAVYISSVVLFGacieGVVLRDKFGEAVNGNLVVGTLAWPSP--WVIVIGSFFSTCGAGLQSLT 460
Cdd:COG0531    218 PKRNIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASIL 293
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  461 GAPRLLQAISRDGIVPflQVFGH-GKANGEPTWALLLTACICEIGILI--ASLDEVAPILSMFFLMCYMFVNLACAVQtL 537
Cdd:COG0531    294 GASRLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALAVIVL-R 370
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958759707  538 LRTPNWRPRFRYYHWTLSFLGMSLCLALMFIC---SWYYALVAMLIAGLIYKYIEYR 591
Cdd:COG0531    371 RRRPDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
SLC12 pfam03522
Solute carrier family 12;
645-1072 5.03e-24

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 106.16  E-value: 5.03e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  645 PQLLSLTSQLKAGKGLTIVGSVLEGTfldnHPQAQRAE--ESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGL 722
Cdd:pfam03522    2 PALVDFAHLITKNVSLMICGHVVKGR----LSQKLRSElqKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKL 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  723 QHNTVLVGWPRNWR-----------------------------------------------------------QKEDHQT 743
Cdd:pfam03522   78 KPNILLMGYKSDWRtcdkeeleeyfnvihdafdlqyavailrlpegldvshllqdqdteelglgdetnssyaeQSSEEQS 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  744 WRNFIELVRETTAGH-------LALLVTKNVSMFPGNPE------------------------------RFSEGSIDVWW 786
Cdd:pfam03522  158 TSNSKQDDDKSKLSKkdsnlslSPDKSTKNPSGKDSSKSdklkkkspsiilrtasnekeilnnitqfqkKQKKGTIDVWW 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  787 IVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRIT-AEVEVVemheSDISAYTYEKTlvm 865
Cdd:pfam03522  238 LYDDGGLTLLLPYILSTRSKWSDCKLRVFALGNRKDELEEEQRNMASLLSKFRIDySDLTVI----PDITKKPKKET--- 310
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  866 eqrsqilKQMH--LTKNEREREiqsitdesrgsirrknpantrlrlnvpeetacdnEEKPEEEVQLIhdqsapscpsssp 943
Cdd:pfam03522  311 -------KKFFdeLIEPFRLHE----------------------------------DDKEEESAEKI------------- 336
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  944 spgeepegegeTDPEKVHLtwtKDKSAAQknkgpspvssegikdffsmkpewenlnqsnvrrmhtaVRLNEVIVNKSRDA 1023
Cdd:pfam03522  337 -----------TDSELEAL---KEKTNRQ-------------------------------------LRLRELLLEHSSDA 365
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1958759707 1024 KLVLLNMPGPPRNRNGDENYMEFLEVLTEQLDRVMLVRGGGREVITIYS 1072
Cdd:pfam03522  366 NLIVMTLPMPRKGTVSAPLYMAWLETLTKDLPPFLLVRGNQTSVLTFYS 414
AA_permease_2 pfam13520
Amino acid permease;
340-588 8.65e-14

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 74.65  E-value: 8.65e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  340 PVDMDHPYVFSDMTSYFTLLVGIYFpSVTGIMAGSNRSGDLRdaQKSIPTGTILAIATTSAVYISSVVLFGACI--EGVV 417
Cdd:pfam13520  175 LSGEWHTFFPDGWPGVFAGFLGVLW-SFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYILVNIAFFGVVpdDEIA 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  418 LRD-------KFGEAVNGNLVVGtlawpspwVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEP 490
Cdd:pfam13520  252 LSSglgqvaaLLFQAVGGKWGAI--------IVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFGSP 323
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  491 TWALLLTACICEIGILIASLDEVAPI----LSMFFLMCYMFVNLACAVqtLLRTPNWRPRFRYYHWTLSFLGMsLCLALM 566
Cdd:pfam13520  324 IRAIILTAILSLILLLLFLLSPAAYNallsLSAYGYLLSYLLPIIGLL--ILRKKRPDLGRIPGRWPVAIFGI-LFSLFL 400
                          250       260
                   ....*....|....*....|..
gi 1958759707  567 FICSWYYALVAMLIAGLIYKYI 588
Cdd:pfam13520  401 IVALFFPPVGPATGSSLNYAII 422
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
378-579 5.80e-04

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 43.58  E-value: 5.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  378 GDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVN-GNLVVGTLAWPSPwvIVIGsfFSTCGAGL 456
Cdd:TIGR00911  259 EEVKNPYRTLPIAIIISMPIVTFIYVLTNIAYFTVLSPEELLASLAVAVDfGERLLGVMSWAMP--ALVG--LSCFGSVN 334
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958759707  457 QSLTGAPRLLQAISRDGIVPFLQVFGHGKANgEPTWALLLTaciCEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQT 536
Cdd:TIGR00911  335 GSLFSSSRLFFVGGREGHLPSLLSMIHVKRL-TPLPSLLIV---CTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLL 410
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1958759707  537 LLR--TPNWRPRFRyyhwtlsflgMSLCLALMFICSWYYALVAML 579
Cdd:TIGR00911  411 WLRykRPEMNRPIK----------VPLFFPVFFLLSCLFLIILSL 445
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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