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Conserved domains on  [gi|1953299597|ref|XP_038545070|]
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pleiotrophin [Canis lupus familiaris]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTN_MK_N super family cl02505
PTN/MK heparin-binding protein family, N-terminal domain;
47-131 8.89e-41

PTN/MK heparin-binding protein family, N-terminal domain;


The actual alignment was detected with superfamily member smart00193:

Pssm-ID: 470593  Cd Length: 80  Bit Score: 131.93  E-value: 8.89e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953299597   47 CGEWQWSVCVPTSGDCGLGTREGTrtgaeCKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSLKRAL 126
Cdd:smart00193   1 CGEWQWGPCIPNSKDCGLGTREGT-----CGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKAL 75


                   ....*
gi 1953299597  127 HNADC 131
Cdd:smart00193  76 YNADC 80
 
Name Accession Description Interval E-value
PTN smart00193
Pleiotrophin / midkine family; Heparin-binding domain family.
 47-131 8.89e-41

Pleiotrophin / midkine family; Heparin-binding domain family.


Pssm-ID: 128490  Cd Length: 80  Bit Score: 131.93  E-value: 8.89e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953299597   47 CGEWQWSVCVPTSGDCGLGTREGTrtgaeCKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSLKRAL 126
Cdd:smart00193   1 CGEWQWGPCIPNSKDCGLGTREGT-----CGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKAL 75


                   ....*
gi 1953299597  127 HNADC 131
Cdd:smart00193  76 YNADC 80
PTN_MK_C pfam01091
PTN/MK heparin-binding protein family, C-terminal domain;
96-151 1.09e-22

PTN/MK heparin-binding protein family, C-terminal domain;


Pssm-ID: 460059  Cd Length: 65  Bit Score: 85.58  E-value: 1.09e-22
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953299597  96 GAECKYQFQAWGECDLNTALKTRTGSLKRALHNADCQKTVTISKPCGKLTKPKPQA 151
Cdd:pfam01091   1 GADCKYKFGAWGECDPATGTKTRTGTLKKALFNAECQQTVSVTKPCKPKTKTKAKG 56
 
Name Accession Description Interval E-value
PTN smart00193
Pleiotrophin / midkine family; Heparin-binding domain family.
 47-131 8.89e-41

Pleiotrophin / midkine family; Heparin-binding domain family.


Pssm-ID: 128490  Cd Length: 80  Bit Score: 131.93  E-value: 8.89e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953299597   47 CGEWQWSVCVPTSGDCGLGTREGTrtgaeCKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSLKRAL 126
Cdd:smart00193   1 CGEWQWGPCIPNSKDCGLGTREGT-----CGQETRKLKCKIPCNWKKQFGADCKYKFESWGECDANTGLKTRSGTLKKAL 75


                   ....*
gi 1953299597  127 HNADC 131
Cdd:smart00193  76 YNADC 80
PTN_MK_C pfam01091
PTN/MK heparin-binding protein family, C-terminal domain;
96-151 1.09e-22

PTN/MK heparin-binding protein family, C-terminal domain;


Pssm-ID: 460059  Cd Length: 65  Bit Score: 85.58  E-value: 1.09e-22
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953299597  96 GAECKYQFQAWGECDLNTALKTRTGSLKRALHNADCQKTVTISKPCGKLTKPKPQA 151
Cdd:pfam01091   1 GADCKYKFGAWGECDPATGTKTRTGTLKKALFNAECQQTVSVTKPCKPKTKTKAKG 56
PTN_MK_N pfam05196
PTN/MK heparin-binding protein family, N-terminal domain;
45-95 3.59e-21

PTN/MK heparin-binding protein family, N-terminal domain;


Pssm-ID: 461582  Cd Length: 57  Bit Score: 81.35  E-value: 3.59e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1953299597  45 SDCGEWQWSVCVPTSGDCGLGTREGTrtgaeCKQTMKTQRCKIPCNWKKQF 95
Cdd:pfam05196  12 SDCAEWQWGKCVPNSGDCGLGFREGT-----CKEQTKKIKCKIPCNWKKEF 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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