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Conserved domains on  [gi|1953273923|ref|XP_038534710|]
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melanocyte protein PMEL isoform X3 [Canis lupus familiaris]

Protein Classification

PKD domain-containing protein( domain architecture ID 10638278)

PKD domain-containing protein containing one or more repeats of the polycystic kidney disease (PKD) motif

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PKAT_KLD pfam20433
PKAT, KLD domain; This is the Kringle-like domain (KLD) found in Melanocyte protein PMEL, ...
 529-580 7.72e-19

PKAT, KLD domain; This is the Kringle-like domain (KLD) found in Melanocyte protein PMEL, Transmembrane glycoprotein NMB (GPNMB) and TMEM130, which is downstream the PKD domain. It contains six highly conserved cysteine residues that form the disulphide bonds of mature PMEL dimers. (Chrystal et. al., Molecules 2021, 26(12), 3529; https://doi.org/10.3390/molecules26123529). This domain is perfectly conserved in PMEL and GPNMB which suggests that GPNMB also forms dimers. PMEL and GPNMB, together with TMEM130 (its most ancient paralogue), have a conserved domain architecture and have been recently described as the PKAT (PKD- and KLD-Associated Transmembrane) protein family (Chrystal et. al., Molecules 2021, 26(12), 3529; https://doi.org/10.3390/molecules26123529). PMEL and GPNMB share overlapping phenotypes and disease associations, such as melanin-based pigmentation, cancer, neurodegenerative disease and glaucoma.


:

Pssm-ID: 466582  Cd Length: 51  Bit Score: 80.40  E-value: 7.72e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1953273923 529 SCQGGLPKEACMDISSPGCQPPAQRLCQPVPPSPACQLVLHQVLKgGSGTYC 580
Cdd:pfam20433   1 TCQGSLPTEVCTVVSDPTCQTPQNTVCNPVSPSPECQLVLRRAFN-GSGTYC 51
PKD smart00089
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ...
 257-329 3.18e-07

Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.


:

Pssm-ID: 214510 [Multi-domain]  Cd Length: 79  Bit Score: 48.22  E-value: 3.18e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953273923  257 PLTFALRLHDPSgYLSGADLSYTWDFGDHTgtlISRALVVTHTYLESGPITAQVVLQAAIPlTSCGSSPVPVT 329
Cdd:smart00089  12 VAGESVTFTATS-SDDGSIVSYTWDFGDGT---SSTGPTVTHTYTKPGTYTVTLTVTNAVG-SASATVTVVVQ 79
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 292-475 1.60e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.91  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 292 RALVVTHTYLESGPITAQVVLQAAIPLTSCGSS------PVPVTTDG-----HAPT-AEIPGTTAGRVPTAEVISTTPGq 359
Cdd:pfam05109 401 KTLIITRTATNATTTTHKVIFSKAPESTTTSPTlnttgfAAPNTTTGlpsstHVPTnLTAPASTGPTVSTADVTSPTPA- 479

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 360 vptAEPSGATAVQMTTTEVTGTTLAQMPTTegigTTPEQVPTSEVISTTLAETTGTTPEGSTAEPsgTTGEQVTTKESVE 439
Cdd:pfam05109 480 ---GTTSGASPVTPSPSPRDNGTESKAPDM----TSPTSAVTTPTPNATSPTPAVTTPTPNATSP--TLGKTSPTSAVTT 550

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1953273923 440 PTA-GEGPTPETKGPDTNLFVPTEGITGSQSALLDGT 475
Cdd:pfam05109 551 PTPnATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPT 587
 
Name Accession Description Interval E-value
PKAT_KLD pfam20433
PKAT, KLD domain; This is the Kringle-like domain (KLD) found in Melanocyte protein PMEL, ...
 529-580 7.72e-19

PKAT, KLD domain; This is the Kringle-like domain (KLD) found in Melanocyte protein PMEL, Transmembrane glycoprotein NMB (GPNMB) and TMEM130, which is downstream the PKD domain. It contains six highly conserved cysteine residues that form the disulphide bonds of mature PMEL dimers. (Chrystal et. al., Molecules 2021, 26(12), 3529; https://doi.org/10.3390/molecules26123529). This domain is perfectly conserved in PMEL and GPNMB which suggests that GPNMB also forms dimers. PMEL and GPNMB, together with TMEM130 (its most ancient paralogue), have a conserved domain architecture and have been recently described as the PKAT (PKD- and KLD-Associated Transmembrane) protein family (Chrystal et. al., Molecules 2021, 26(12), 3529; https://doi.org/10.3390/molecules26123529). PMEL and GPNMB share overlapping phenotypes and disease associations, such as melanin-based pigmentation, cancer, neurodegenerative disease and glaucoma.


Pssm-ID: 466582  Cd Length: 51  Bit Score: 80.40  E-value: 7.72e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1953273923 529 SCQGGLPKEACMDISSPGCQPPAQRLCQPVPPSPACQLVLHQVLKgGSGTYC 580
Cdd:pfam20433   1 TCQGSLPTEVCTVVSDPTCQTPQNTVCNPVSPSPECQLVLRRAFN-GSGTYC 51
PKD smart00089
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ...
 257-329 3.18e-07

Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.


Pssm-ID: 214510 [Multi-domain]  Cd Length: 79  Bit Score: 48.22  E-value: 3.18e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953273923  257 PLTFALRLHDPSgYLSGADLSYTWDFGDHTgtlISRALVVTHTYLESGPITAQVVLQAAIPlTSCGSSPVPVT 329
Cdd:smart00089  12 VAGESVTFTATS-SDDGSIVSYTWDFGDGT---SSTGPTVTHTYTKPGTYTVTLTVTNAVG-SASATVTVVVQ 79
PKD cd00146
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ...
 253-328 3.61e-07

polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.


Pssm-ID: 238084 [Multi-domain]  Cd Length: 81  Bit Score: 48.26  E-value: 3.61e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953273923 253 LRNHPLTFALRLHDPSGylsGADLSYTWDFGDHTGTLiSRALVVTHTYLESGPITAQVVLQAAIPLTSCGSSPVPV 328
Cdd:cd00146    10 VAELGASVTFSASDSSG---GSIVSYKWDFGDGEVSS-SGEPTVTHTYTKPGTYTVTLTVTNAVGSSSTKTTTVVV 81
PKD pfam00801
PKD domain; This domain was first identified in the Polycystic kidney disease protein PKD1. ...
 255-321 1.63e-06

PKD domain; This domain was first identified in the Polycystic kidney disease protein PKD1. This domain has been predicted to contain an Ig-like fold.


Pssm-ID: 395646 [Multi-domain]  Cd Length: 70  Bit Score: 45.84  E-value: 1.63e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953273923 255 NHPLTFALRLHDpsgylsGADLSYTWDFGDHTGTlISRALVVTHTYLESGPITAQVVLQAAIPLTSC 321
Cdd:pfam00801  11 GQPVTFTATLAD------GSNVTYTWDFGDSPGT-SGSGPTVTHTYLSPGTYTVTLTASNAVGSANA 70
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 292-475 1.60e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.91  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 292 RALVVTHTYLESGPITAQVVLQAAIPLTSCGSS------PVPVTTDG-----HAPT-AEIPGTTAGRVPTAEVISTTPGq 359
Cdd:pfam05109 401 KTLIITRTATNATTTTHKVIFSKAPESTTTSPTlnttgfAAPNTTTGlpsstHVPTnLTAPASTGPTVSTADVTSPTPA- 479

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 360 vptAEPSGATAVQMTTTEVTGTTLAQMPTTegigTTPEQVPTSEVISTTLAETTGTTPEGSTAEPsgTTGEQVTTKESVE 439
Cdd:pfam05109 480 ---GTTSGASPVTPSPSPRDNGTESKAPDM----TSPTSAVTTPTPNATSPTPAVTTPTPNATSP--TLGKTSPTSAVTT 550

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1953273923 440 PTA-GEGPTPETKGPDTNLFVPTEGITGSQSALLDGT 475
Cdd:pfam05109 551 PTPnATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPT 587
COG3291 COG3291
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
272-477 1.92e-03

Uncharacterized conserved protein, PKD repeat domain [Function unknown];


Pssm-ID: 442520 [Multi-domain]  Cd Length: 333  Bit Score: 40.81  E-value: 1.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 272 SGADLSYTWDFGD-HTGTLISralvVTHTYLESGPITAQVVLQAAIPLTSCGSSPVPVTTDGHAPTAEIPGTTAGRVPTA 350
Cdd:COG3291    21 SGNATSYEWDFGDgTTSTEAN----PSHTYTTPGTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 351 EVISTTPGQVPTAEPSGATAVQMTTTEVTGTTLAQMPTTEGIGTTPEQVPTSEVISTTLAETTGTTPEGSTAEPSGTTGE 430
Cdd:COG3291    97 ANGGATTVVAGSTVGTGVATSTTTAAAPGGGGGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNP 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1953273923 431 QVTTKESVEPTAGEGPTPETKGPDTNLFVPTEGITGSQSALLDGTAT 477
Cdd:COG3291   177 SVTTDTVTTLTGSYTGTIVGGSGSGTVTSGTAGVTTGATSGTSGTGS 223
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 229-310 6.90e-03

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 40.07  E-value: 6.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923  229 ITDQVPFSVSvSQLQALDGGNKH--FLRNHPLTF-ALRLHDPSGYLsgadlsYTWDFGDHTGTLISRALVVTHTYLESGP 305
Cdd:TIGR00864 1075 ISQQINMSVR-AILPRVAIGTEDglLLAGKPADFeAHPLPSPGGIH------YEWDFGDGSALLQGRQPAAAHTFAKRGP 1147


                   ....*
gi 1953273923  306 ITAQV 310
Cdd:TIGR00864 1148 FHVCL 1152
 
Name Accession Description Interval E-value
PKAT_KLD pfam20433
PKAT, KLD domain; This is the Kringle-like domain (KLD) found in Melanocyte protein PMEL, ...
 529-580 7.72e-19

PKAT, KLD domain; This is the Kringle-like domain (KLD) found in Melanocyte protein PMEL, Transmembrane glycoprotein NMB (GPNMB) and TMEM130, which is downstream the PKD domain. It contains six highly conserved cysteine residues that form the disulphide bonds of mature PMEL dimers. (Chrystal et. al., Molecules 2021, 26(12), 3529; https://doi.org/10.3390/molecules26123529). This domain is perfectly conserved in PMEL and GPNMB which suggests that GPNMB also forms dimers. PMEL and GPNMB, together with TMEM130 (its most ancient paralogue), have a conserved domain architecture and have been recently described as the PKAT (PKD- and KLD-Associated Transmembrane) protein family (Chrystal et. al., Molecules 2021, 26(12), 3529; https://doi.org/10.3390/molecules26123529). PMEL and GPNMB share overlapping phenotypes and disease associations, such as melanin-based pigmentation, cancer, neurodegenerative disease and glaucoma.


Pssm-ID: 466582  Cd Length: 51  Bit Score: 80.40  E-value: 7.72e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1953273923 529 SCQGGLPKEACMDISSPGCQPPAQRLCQPVPPSPACQLVLHQVLKgGSGTYC 580
Cdd:pfam20433   1 TCQGSLPTEVCTVVSDPTCQTPQNTVCNPVSPSPECQLVLRRAFN-GSGTYC 51
PKD smart00089
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ...
 257-329 3.18e-07

Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.


Pssm-ID: 214510 [Multi-domain]  Cd Length: 79  Bit Score: 48.22  E-value: 3.18e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953273923  257 PLTFALRLHDPSgYLSGADLSYTWDFGDHTgtlISRALVVTHTYLESGPITAQVVLQAAIPlTSCGSSPVPVT 329
Cdd:smart00089  12 VAGESVTFTATS-SDDGSIVSYTWDFGDGT---SSTGPTVTHTYTKPGTYTVTLTVTNAVG-SASATVTVVVQ 79
PKD cd00146
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ...
 253-328 3.61e-07

polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.


Pssm-ID: 238084 [Multi-domain]  Cd Length: 81  Bit Score: 48.26  E-value: 3.61e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953273923 253 LRNHPLTFALRLHDPSGylsGADLSYTWDFGDHTGTLiSRALVVTHTYLESGPITAQVVLQAAIPLTSCGSSPVPV 328
Cdd:cd00146    10 VAELGASVTFSASDSSG---GSIVSYKWDFGDGEVSS-SGEPTVTHTYTKPGTYTVTLTVTNAVGSSSTKTTTVVV 81
PKD pfam00801
PKD domain; This domain was first identified in the Polycystic kidney disease protein PKD1. ...
 255-321 1.63e-06

PKD domain; This domain was first identified in the Polycystic kidney disease protein PKD1. This domain has been predicted to contain an Ig-like fold.


Pssm-ID: 395646 [Multi-domain]  Cd Length: 70  Bit Score: 45.84  E-value: 1.63e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953273923 255 NHPLTFALRLHDpsgylsGADLSYTWDFGDHTGTlISRALVVTHTYLESGPITAQVVLQAAIPLTSC 321
Cdd:pfam00801  11 GQPVTFTATLAD------GSNVTYTWDFGDSPGT-SGSGPTVTHTYLSPGTYTVTLTASNAVGSANA 70
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 292-475 1.60e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.91  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 292 RALVVTHTYLESGPITAQVVLQAAIPLTSCGSS------PVPVTTDG-----HAPT-AEIPGTTAGRVPTAEVISTTPGq 359
Cdd:pfam05109 401 KTLIITRTATNATTTTHKVIFSKAPESTTTSPTlnttgfAAPNTTTGlpsstHVPTnLTAPASTGPTVSTADVTSPTPA- 479

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 360 vptAEPSGATAVQMTTTEVTGTTLAQMPTTegigTTPEQVPTSEVISTTLAETTGTTPEGSTAEPsgTTGEQVTTKESVE 439
Cdd:pfam05109 480 ---GTTSGASPVTPSPSPRDNGTESKAPDM----TSPTSAVTTPTPNATSPTPAVTTPTPNATSP--TLGKTSPTSAVTT 550

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1953273923 440 PTA-GEGPTPETKGPDTNLFVPTEGITGSQSALLDGT 475
Cdd:pfam05109 551 PTPnATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPT 587
COG3291 COG3291
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
272-477 1.92e-03

Uncharacterized conserved protein, PKD repeat domain [Function unknown];


Pssm-ID: 442520 [Multi-domain]  Cd Length: 333  Bit Score: 40.81  E-value: 1.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 272 SGADLSYTWDFGD-HTGTLISralvVTHTYLESGPITAQVVLQAAIPLTSCGSSPVPVTTDGHAPTAEIPGTTAGRVPTA 350
Cdd:COG3291    21 SGNATSYEWDFGDgTTSTEAN----PSHTYTTPGTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923 351 EVISTTPGQVPTAEPSGATAVQMTTTEVTGTTLAQMPTTEGIGTTPEQVPTSEVISTTLAETTGTTPEGSTAEPSGTTGE 430
Cdd:COG3291    97 ANGGATTVVAGSTVGTGVATSTTTAAAPGGGGGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNP 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1953273923 431 QVTTKESVEPTAGEGPTPETKGPDTNLFVPTEGITGSQSALLDGTAT 477
Cdd:COG3291   177 SVTTDTVTTLTGSYTGTIVGGSGSGTVTSGTAGVTTGATSGTSGTGS 223
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 229-310 6.90e-03

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 40.07  E-value: 6.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953273923  229 ITDQVPFSVSvSQLQALDGGNKH--FLRNHPLTF-ALRLHDPSGYLsgadlsYTWDFGDHTGTLISRALVVTHTYLESGP 305
Cdd:TIGR00864 1075 ISQQINMSVR-AILPRVAIGTEDglLLAGKPADFeAHPLPSPGGIH------YEWDFGDGSALLQGRQPAAAHTFAKRGP 1147


                   ....*
gi 1953273923  306 ITAQV 310
Cdd:TIGR00864 1148 FHVCL 1152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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