|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
15-460 |
4.80e-97 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 301.43 E-value: 4.80e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 15 SKFRNVYGKVANRE-HCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSflVIPLEQTGRIEPNYPKVCGHQGNVLDI 93
Cdd:PTZ00421 4 SRFRHTQGVPARPDrHFLNVTPSTALWDCSNTIACNDRFIAVPWQQLGSTA--VLKHTDYGKLASNPPILLGQEGPIIDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 94 KWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPV 173
Cdd:PTZ00421 82 AFNPFDPQKLFTASEDGTIMGWGIPEEGLTQNISDPIVHLQGHTKKVGIVSFHPSAMNVLASAGADMVVNVWDVERGKAV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 174 KMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANC-KNHRVNRVVFLGNMKRLLTTGVSRWNTRQIAL 252
Cdd:PTZ00421 162 EVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAhASAKSQRCLWAKRKDLIITLGCSKSQQRQIML 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 253 WDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPFLSYlmEFRSPAPQKGLGVMPKHGLDV 332
Cdd:PTZ00421 242 WDTRKMASPYSTVDLDQSSALFIPFFDEDTNLLYIGSKGEGNIRCFELMNERLTFCS--SYSSVEPHKGLCMMPKWSLDT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 333 SACEVFRFYKLvTLKGLIePISMIVPRR-SDS-YQEDIYPMTPGTEPALTPDEWLGGMNRDPVLMSLKEGYKKSSKMVFK 410
Cdd:PTZ00421 320 RKCEIARFYAL-TYHSLY-TIQMLLPRKqADSeLQVDVYPPTFADHPAITADEYFSGGNAEPLVYDMSAVFDGTSPELMG 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 411 AP------IKEKKSVVVNGID-----------------LLENVPPRTEN----------ELLRMFFRQQDEIRRLKEELA 457
Cdd:PTZ00421 398 ASalspsgKPRHSGVSVPASTsamthsfddntskhadpCAMGVKRMDEGilderlgrlqALSEKLRTQHEEIKRCREALQ 477
|
...
gi 1952744023 458 QKD 460
Cdd:PTZ00421 478 KKE 480
|
|
| DUF1899 |
pfam08953 |
Domain of unknown function (DUF1899); This set of domains is found in various eukaryotic ... |
12-75 |
1.39e-33 |
|
Domain of unknown function (DUF1899); This set of domains is found in various eukaryotic proteins. Function is unknown.
Pssm-ID: 462645 [Multi-domain] Cd Length: 66 Bit Score: 121.07 E-value: 1.39e-33
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1952744023 12 YRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGR 75
Cdd:pfam08953 3 VRASKFRHVYGKPAKKELCYDNIKVTKNAWDSNFIAANPKFLAVNWESSGGGAFAVLPLNQTGR 66
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
84-305 |
3.97e-28 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 113.20 E-value: 3.97e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 84 CGHQGNVLDIKWNPFiDNIIASCSEDTSVRIWEIPEGGLKRnmteallELHGHSRRVGLVEWHPTtNNILFSAGYDYKVL 163
Cdd:cd00200 48 KGHTGPVRDVAASAD-GTYLASGSSDKTIRLWDLETGECVR-------TLTGHTSYVSSVAFSPD-GRILSSSSRDKTIK 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 164 IWNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGvs 243
Cdd:cd00200 119 VWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSS-- 196
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1952744023 244 rwNTRQIALWDQ--EDLSMPLIEEEiDGLSGLLFpfydADTHMLYLAGKGDGNIRYYEISTEKP 305
Cdd:cd00200 197 --SDGTIKLWDLstGKCLGTLRGHE-NGVNSVAF----SPDGYLLASGSEDGTIRVWDLRTGEC 253
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
85-305 |
6.85e-26 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 109.23 E-value: 6.85e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 85 GHQGNVLDIKWNPfiD-NIIASCSEDTSVRIWEIPEGGLkrnmteaLLELHGHSRRVGLVEWHPTtNNILFSAGYDYKVL 163
Cdd:COG2319 160 GHSGAVTSVAFSP--DgKLLASGSDDGTVRLWDLATGKL-------LRTLTGHTGAVRSVAFSPD-GKLLASGSADGTVR 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 164 IWNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGvs 243
Cdd:COG2319 230 LWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGS-- 307
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1952744023 244 rwNTRQIALWDQEDlsmpliEEEIDGLSGLLFPFYDA----DTHMLYLAGkGDGNIRYYEISTEKP 305
Cdd:COG2319 308 --DDGTVRLWDLAT------GKLLRTLTGHTGAVRSVafspDGKTLASGS-DDGTVRLWDLATGEL 364
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
85-116 |
5.78e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 43.07 E-value: 5.78e-06
10 20 30
....*....|....*....|....*....|..
gi 1952744023 85 GHQGNVLDIKWNPFiDNIIASCSEDTSVRIWE 116
Cdd:smart00320 10 GHTGPVTSVAFSPD-GKYLASGSDDGTIKLWD 40
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
15-460 |
4.80e-97 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 301.43 E-value: 4.80e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 15 SKFRNVYGKVANRE-HCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSflVIPLEQTGRIEPNYPKVCGHQGNVLDI 93
Cdd:PTZ00421 4 SRFRHTQGVPARPDrHFLNVTPSTALWDCSNTIACNDRFIAVPWQQLGSTA--VLKHTDYGKLASNPPILLGQEGPIIDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 94 KWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPV 173
Cdd:PTZ00421 82 AFNPFDPQKLFTASEDGTIMGWGIPEEGLTQNISDPIVHLQGHTKKVGIVSFHPSAMNVLASAGADMVVNVWDVERGKAV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 174 KMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANC-KNHRVNRVVFLGNMKRLLTTGVSRWNTRQIAL 252
Cdd:PTZ00421 162 EVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAhASAKSQRCLWAKRKDLIITLGCSKSQQRQIML 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 253 WDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPFLSYlmEFRSPAPQKGLGVMPKHGLDV 332
Cdd:PTZ00421 242 WDTRKMASPYSTVDLDQSSALFIPFFDEDTNLLYIGSKGEGNIRCFELMNERLTFCS--SYSSVEPHKGLCMMPKWSLDT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 333 SACEVFRFYKLvTLKGLIePISMIVPRR-SDS-YQEDIYPMTPGTEPALTPDEWLGGMNRDPVLMSLKEGYKKSSKMVFK 410
Cdd:PTZ00421 320 RKCEIARFYAL-TYHSLY-TIQMLLPRKqADSeLQVDVYPPTFADHPAITADEYFSGGNAEPLVYDMSAVFDGTSPELMG 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 411 AP------IKEKKSVVVNGID-----------------LLENVPPRTEN----------ELLRMFFRQQDEIRRLKEELA 457
Cdd:PTZ00421 398 ASalspsgKPRHSGVSVPASTsamthsfddntskhadpCAMGVKRMDEGilderlgrlqALSEKLRTQHEEIKRCREALQ 477
|
...
gi 1952744023 458 QKD 460
Cdd:PTZ00421 478 KKE 480
|
|
| PTZ00420 |
PTZ00420 |
coronin; Provisional |
18-445 |
1.83e-63 |
|
coronin; Provisional
Pssm-ID: 240412 [Multi-domain] Cd Length: 568 Bit Score: 215.58 E-value: 1.83e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 18 RNVYGKVANRehCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRiEPNYPKVCGHQGNVLDIKWNP 97
Cdd:PTZ00420 8 KNLYPDPSNN--LFDDLRICSRVIDSCGIACSSGFVAVPWEVEGGGLIGAIRLENQMR-KPPVIKLKGHTSSILDLQFNP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 98 FIDNIIASCSEDTSVRIWEIPEGGLKRN-MTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLD-------V 169
Cdd:PTZ00420 85 CFSEILASGSEDLTIRVWEIPHNDESVKeIKDPQCILKGHKKKISIIDWNPMNYYIMCSSGFDSFVNIWDIEnekrafqI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 170 GEPVKMIDchsdvilcMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQE-------ANCKNHRVNRvvFLGNMKRLLTTGV 242
Cdd:PTZ00420 165 NMPKKLSS--------LKWNIKGNLLSGTCVGKHMHIIDPRKQEIASSfhihdggKNTKNIWIDG--LGGDDNYILSTGF 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 243 SRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKpfLSYLMEFRSPAPQKGL 322
Cdd:PTZ00420 235 SKNNMREMKLWDLKNTTSALVTMSIDNASAPLIPHYDESTGLIYLIGKGDGNCRYYQHSLGS--IRKVNEYKSCSPFRSF 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 323 GVMPKHGLDVSACEVFRFYKLVTlKGLIEPISMIVPRRSDS-YQEDIYPMTPGTEPALTPDEWLGGMNRDPVLMSLKEGY 401
Cdd:PTZ00420 313 GFLPKQICDVYKCEIGRVYKNEN-NSSIRPISFYVPRKNPTkFQEDLYPPILMHDPERSSRNWIDGKDNKMKRINIKDLT 391
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1952744023 402 KKSSKMV--FKAPIKEKKSVVVNGidllENVPPRTenELLRMFFRQ 445
Cdd:PTZ00420 392 EDDLRITkkYKFVPQSFNSIIIGE----NYTSKRT--SIIRQFTKK 431
|
|
| DUF1899 |
pfam08953 |
Domain of unknown function (DUF1899); This set of domains is found in various eukaryotic ... |
12-75 |
1.39e-33 |
|
Domain of unknown function (DUF1899); This set of domains is found in various eukaryotic proteins. Function is unknown.
Pssm-ID: 462645 [Multi-domain] Cd Length: 66 Bit Score: 121.07 E-value: 1.39e-33
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1952744023 12 YRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGR 75
Cdd:pfam08953 3 VRASKFRHVYGKPAKKELCYDNIKVTKNAWDSNFIAANPKFLAVNWESSGGGAFAVLPLNQTGR 66
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
84-305 |
3.97e-28 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 113.20 E-value: 3.97e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 84 CGHQGNVLDIKWNPFiDNIIASCSEDTSVRIWEIPEGGLKRnmteallELHGHSRRVGLVEWHPTtNNILFSAGYDYKVL 163
Cdd:cd00200 48 KGHTGPVRDVAASAD-GTYLASGSSDKTIRLWDLETGECVR-------TLTGHTSYVSSVAFSPD-GRILSSSSRDKTIK 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 164 IWNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGvs 243
Cdd:cd00200 119 VWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSS-- 196
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1952744023 244 rwNTRQIALWDQ--EDLSMPLIEEEiDGLSGLLFpfydADTHMLYLAGKGDGNIRYYEISTEKP 305
Cdd:cd00200 197 --SDGTIKLWDLstGKCLGTLRGHE-NGVNSVAF----SPDGYLLASGSEDGTIRVWDLRTGEC 253
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
85-305 |
6.85e-26 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 109.23 E-value: 6.85e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 85 GHQGNVLDIKWNPfiD-NIIASCSEDTSVRIWEIPEGGLkrnmteaLLELHGHSRRVGLVEWHPTtNNILFSAGYDYKVL 163
Cdd:COG2319 160 GHSGAVTSVAFSP--DgKLLASGSDDGTVRLWDLATGKL-------LRTLTGHTGAVRSVAFSPD-GKLLASGSADGTVR 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 164 IWNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGvs 243
Cdd:COG2319 230 LWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGS-- 307
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1952744023 244 rwNTRQIALWDQEDlsmpliEEEIDGLSGLLFPFYDA----DTHMLYLAGkGDGNIRYYEISTEKP 305
Cdd:COG2319 308 --DDGTVRLWDLAT------GKLLRTLTGHTGAVRSVafspDGKTLASGS-DDGTVRLWDLATGEL 364
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
85-304 |
4.17e-25 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 104.72 E-value: 4.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 85 GHQGNVLDIKWNPfIDNIIASCSEDTSVRIWEIPEGGLKRnmteallELHGHSRRVGLVEWHPTTNNiLFSAGYDYKVLI 164
Cdd:cd00200 7 GHTGGVTCVAFSP-DGKLLATGSGDGTIKVWDLETGELLR-------TLKGHTGPVRDVAASADGTY-LASGSSDKTIRL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 165 WNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNmKRLLTTGvsr 244
Cdd:cd00200 78 WDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPD-GTFVASS--- 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1952744023 245 WNTRQIALWDQEDLS-MPLIEEEIDGLSGLLFpfyDADTHMLYLAGkGDGNIRYYEISTEK 304
Cdd:cd00200 154 SQDGTIKLWDLRTGKcVATLTGHTGEVNSVAF---SPDGEKLLSSS-SDGTIKLWDLSTGK 210
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
85-254 |
2.63e-22 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 96.64 E-value: 2.63e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 85 GHQGNVLDIKWNPFiDNIIASCSEDTSVRIWEIPEGGLKRNmtealleLHGHSRRVGLVEWHPTTNNILFSAGyDYKVLI 164
Cdd:cd00200 133 GHTDWVNSVAFSPD-GTFVASSSQDGTIKLWDLRTGKCVAT-------LTGHTGEVNSVAFSPDGEKLLSSSS-DGTIKL 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 165 WNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSR 244
Cdd:cd00200 204 WDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADG 283
|
170
....*....|
gi 1952744023 245 WntrqIALWD 254
Cdd:cd00200 284 T----IRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
85-254 |
2.80e-21 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 95.75 E-value: 2.80e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 85 GHQGNVLDIKWNPfiDN-IIASCSEDTSVRIWEIPEGglkrnmtEALLELHGHSRRVGLVEWHPTtNNILFSAGYDYKVL 163
Cdd:COG2319 244 GHSGSVRSVAFSP--DGrLLASGSADGTVRLWDLATG-------ELLRTLTGHSGGVNSVAFSPD-GKLLASGSDDGTVR 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 164 IWNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEAncKNH--RVNRVVFLGNMKRLLTTG 241
Cdd:COG2319 314 LWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTL--TGHtgAVTSVAFSPDGRTLASGS 391
|
170
....*....|...
gi 1952744023 242 vsrwNTRQIALWD 254
Cdd:COG2319 392 ----ADGTVRLWD 400
|
|
| WD40_4 |
pfam16300 |
Type of WD40 repeat; Most members of this family form part of the 7-bladed beta-propeller at ... |
350-392 |
1.78e-19 |
|
Type of WD40 repeat; Most members of this family form part of the 7-bladed beta-propeller at the N-terminus of coronin proteins.
Pssm-ID: 465087 [Multi-domain] Cd Length: 44 Bit Score: 81.41 E-value: 1.78e-19
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1952744023 350 IEPISMIVPRRS-DSYQEDIYPMTPGTEPALTPDEWLGGMNRDP 392
Cdd:pfam16300 1 IEPISFTVPRKSkEDFQDDLYPDTAGTEPALTAEEWLSGKNAEP 44
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
85-254 |
5.72e-19 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 88.81 E-value: 5.72e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 85 GHQGNVLDIKWNPfIDNIIASCSEDTSVRIWEIPEGGLKRnmteallELHGHSRRVGLVEWHPTtNNILFSAGYDYKVLI 164
Cdd:COG2319 76 GHTAAVLSVAFSP-DGRLLASASADGTVRLWDLATGLLLR-------TLTGHTGAVRSVAFSPD-GKTLASGSADGTVRL 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 165 WNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGvsr 244
Cdd:COG2319 147 WDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGS--- 223
|
170
....*....|
gi 1952744023 245 wNTRQIALWD 254
Cdd:COG2319 224 -ADGTVRLWD 232
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
85-168 |
5.66e-09 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 58.00 E-value: 5.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 85 GHQGNVLDIKWNPFiDNIIASCSEDTSVRIWEIPEGGLkrnmteaLLELHGHSRRVGLVEWHPTtNNILFSAGYDYKVLI 164
Cdd:COG2319 328 GHTGAVRSVAFSPD-GKTLASGSDDGTVRLWDLATGEL-------LRTLTGHTGAVTSVAFSPD-GRTLASGSADGTVRL 398
|
....
gi 1952744023 165 WNLD 168
Cdd:COG2319 399 WDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
172-305 |
1.16e-06 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 50.03 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 172 PVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEanCKNHR--VNRVVFLGNMKRLLTTGvsrwNTRQ 249
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRT--LKGHTgpVRDVAASADGTYLASGS----SDKT 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1952744023 250 IALWDQEDLSMP--LIEEEiDGLSGLLFpfyDADTHMLyLAGKGDGNIRYYEISTEKP 305
Cdd:cd00200 75 IRLWDLETGECVrtLTGHT-SYVSSVAF---SPDGRIL-SSSSRDKTIKVWDVETGKC 127
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
85-116 |
5.78e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 43.07 E-value: 5.78e-06
10 20 30
....*....|....*....|....*....|..
gi 1952744023 85 GHQGNVLDIKWNPFiDNIIASCSEDTSVRIWE 116
Cdd:smart00320 10 GHTGPVTSVAFSPD-GKYLASGSDDGTIKLWD 40
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
79-324 |
1.20e-05 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 47.77 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 79 NYPKV-CGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEallelhgHSRRVGLVEWHPTTNNILFSAG 157
Cdd:PLN00181 523 HYPVVeLASRSKLSGICWNSYIKSQVASSNFEGVVQVWDVARSQLVTEMKE-------HEKRVWSIDYSSADPTLLASGS 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 158 YDYKVLIWNLDVGEPVKMIDCHSDvILCMSFNTD-GSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHR-VNRVVFLGNmk 235
Cdd:PLN00181 596 DDGSVKLWSINQGVSIGTIKTKAN-ICCVQFPSEsGRSLAFGSADHKVYYYDLRNPKLPLCTMIGHSKtVSYVRFVDS-- 672
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 236 rllTTGVSRWNTRQIALWdqeDLSMP---LIEEEIDGLSGL--LFPFYDADTHMLYLAGKGDGN-IRYYEISTEKPFLSY 309
Cdd:PLN00181 673 ---STLVSSSTDNTLKLW---DLSMSisgINETPLHSFMGHtnVKNFVGLSVSDGYIATGSETNeVFVYHKAFPMPVLSY 746
|
250
....*....|....*
gi 1952744023 310 LmeFRSPAPQKGLGV 324
Cdd:PLN00181 747 K--FKTIDPVSGLEV 759
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
170-206 |
2.98e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 41.14 E-value: 2.98e-05
10 20 30
....*....|....*....|....*....|....*..
gi 1952744023 170 GEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRV 206
Cdd:smart00320 2 GELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKL 38
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
170-206 |
3.86e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 40.79 E-value: 3.86e-05
10 20 30
....*....|....*....|....*....|....*..
gi 1952744023 170 GEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRV 206
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKV 37
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
85-116 |
4.89e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 40.41 E-value: 4.89e-05
10 20 30
....*....|....*....|....*....|..
gi 1952744023 85 GHQGNVLDIKWNPFiDNIIASCSEDTSVRIWE 116
Cdd:pfam00400 9 GHTGSVTSLAFSPD-GKLLASGSDDGTVKVWD 39
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
129-305 |
1.02e-04 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 44.52 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 129 ALLELHGHSRRVGLVEWHPTTNNILfSAGYDYKVLIWNLDVGEPVKMIDCHSDVILCMSFNTDGSLLTTTCKDKKLRVIE 208
Cdd:COG2319 28 LLLLLLGLAAAVASLAASPDGARLA-AGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWD 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952744023 209 PRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGvsrwNTRQIALWDQEDLS-MPLIEEEIDGLSGLLFpfyDADTHMLYL 287
Cdd:COG2319 107 LATGLLLRTLTGHTGAVRSVAFSPDGKTLASGS----ADGTVRLWDLATGKlLRTLTGHSGAVTSVAF---SPDGKLLAS 179
|
170
....*....|....*...
gi 1952744023 288 AGkGDGNIRYYEISTEKP 305
Cdd:COG2319 180 GS-DDGTVRLWDLATGKL 196
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
130-166 |
1.54e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 36.14 E-value: 1.54e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1952744023 130 LLELHGHSRRVGLVEWHPTtNNILFSAGYDYKVLIWN 166
Cdd:smart00320 5 LKTLKGHTGPVTSVAFSPD-GKYLASGSDDGTIKLWD 40
|
|
| DivIC |
pfam04977 |
Septum formation initiator; DivIC from B. subtilis is necessary for both vegetative and ... |
439-477 |
3.55e-03 |
|
Septum formation initiator; DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.
Pssm-ID: 428231 [Multi-domain] Cd Length: 69 Bit Score: 36.04 E-value: 3.55e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1952744023 439 LRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNNP 477
Cdd:pfam04977 5 LLTYYQLKQEIAQLQAEIAKLKQENEELEAEIKDLKSDP 43
|
|
|