NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1952711416|ref|XP_038312362|]
View 

diacylglycerol O-acyltransferase 2 isoform X1 [Canis lupus familiaris]

Protein Classification

2-acylglycerol O-acyltransferase family protein( domain architecture ID 11146611)

2-acylglycerol O-acyltransferase family protein such as 2-acylglycerol O-acyltransferase, which catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DAGAT pfam03982
Diacylglycerol acyltransferase; The terminal step of triacylglycerol (TAG) formation is ...
 221-517 0e+00

Diacylglycerol acyltransferase; The terminal step of triacylglycerol (TAG) formation is catalyzed by the enzyme diacylglycerol acyltransferase (DAGAT).


:

Pssm-ID: 112781 [Multi-domain]  Cd Length: 297  Bit Score: 519.68  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 221 MYTFCTDCWLIAVLYFTWLAFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAF 300
Cdd:pfam03982   1 FVLFFTPQWSLLVLYALWLFYDWNSPKRGGYRSNWARNWRIWKWFANYFPVKLHKTAELPPNRNYLFGYHPHGILSVGAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 301 CNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNGSGNAIIIVVGGAAESLSSMPGK 380
Cdd:pfam03982  81 SNFSTNATGFMDKFPGIRPNICTLAGQFYTPFRREILLSLGLIEVSRESIEYVLDKCGKGRAVVLVVGGAAEALEAHPGK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 381 NAVTLRNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYS 460
Cdd:pfam03982 161 HTLTLKNRKGFVRIALKTGADLVPVYSFGENDVYKQWENPEGSRLRWVQEKLKRAIGFSPPIFHGRGVFNSYTFGLLPFR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1952711416 461 KPITTVVGEPITIPKLEHPTQQDIDLYHAMYMEALVKLFDKHKTKFGLPETEVLEVN 517
Cdd:pfam03982 241 KPITTVVGAPIEVTKTLNPTQEQIDELHGQYMEALRELFEEHKTKFGVPPDTDLVLN 297
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 3-143 5.26e-06

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.21  E-value: 5.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   3 LAIPSAQAGPRA-HAPAEALVRLHVLGVGAQE-----PRGRGGAAAERAGsspepapappgrgagwNGRPRPARVGPPGC 76
Cdd:PRK07764  362 MLLPSASDDERGlLARLERLERRLGVAGGAGApaaaaPSAAAAAPAAAPA----------------PAAAAPAAAAAPAP 425

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1952711416  77 EVIKRRAPGARAQWPPPTARFRLLLGLRRAPSPAPR-SPLPAPRAASAVPRPPTPELGAKPWPRRPGH 143
Cdd:PRK07764  426 AAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAApSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAA 493
 
Name Accession Description Interval E-value
DAGAT pfam03982
Diacylglycerol acyltransferase; The terminal step of triacylglycerol (TAG) formation is ...
 221-517 0e+00

Diacylglycerol acyltransferase; The terminal step of triacylglycerol (TAG) formation is catalyzed by the enzyme diacylglycerol acyltransferase (DAGAT).


Pssm-ID: 112781 [Multi-domain]  Cd Length: 297  Bit Score: 519.68  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 221 MYTFCTDCWLIAVLYFTWLAFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAF 300
Cdd:pfam03982   1 FVLFFTPQWSLLVLYALWLFYDWNSPKRGGYRSNWARNWRIWKWFANYFPVKLHKTAELPPNRNYLFGYHPHGILSVGAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 301 CNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNGSGNAIIIVVGGAAESLSSMPGK 380
Cdd:pfam03982  81 SNFSTNATGFMDKFPGIRPNICTLAGQFYTPFRREILLSLGLIEVSRESIEYVLDKCGKGRAVVLVVGGAAEALEAHPGK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 381 NAVTLRNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYS 460
Cdd:pfam03982 161 HTLTLKNRKGFVRIALKTGADLVPVYSFGENDVYKQWENPEGSRLRWVQEKLKRAIGFSPPIFHGRGVFNSYTFGLLPFR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1952711416 461 KPITTVVGEPITIPKLEHPTQQDIDLYHAMYMEALVKLFDKHKTKFGLPETEVLEVN 517
Cdd:pfam03982 241 KPITTVVGAPIEVTKTLNPTQEQIDELHGQYMEALRELFEEHKTKFGVPPDTDLVLN 297
LPLAT_MGAT-like cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ...
 265-504 1.14e-51

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.


Pssm-ID: 153249 [Multi-domain]  Cd Length: 212  Bit Score: 174.78  E-value: 1.14e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 265 FRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGL-GAFCNFsteatEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGIC 343
Cdd:cd07987     1 HRKYFRVYEVRGLENIPDEGPALLVHPHGGLPIdGALLAA-----AFLLLFPGRLPRALADHFLFPLPGLRDLLRRLGAV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 344 PVNRDTIDYLLSKngsGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGS 423
Cdd:cd07987    76 PGSRENCVRLLRE---GELVLIFPGGAREALKSKREEYYLLWKKRKGFARLALRAGAPIVPVFTFGEEELFRVLGDPDGP 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 424 WGRWvqkkfqkyigfapcifHGRGLfssdtwgLVPYSKPITTVVGEPI--TIPKLEHPTQQDIDLYHAMYMEALVKLFDK 501
Cdd:cd07987   153 VGKR----------------LFRLL-------PLPRRLPLYPVFGEPIvvPRPPIPDPPDEDVEELHQKYIAALRELIEK 209


                  ...
gi 1952711416 502 HKT 504
Cdd:cd07987   210 HKK 212
PLN02783 PLN02783
diacylglycerol O-acyltransferase
 201-512 8.07e-44

diacylglycerol O-acyltransferase


Pssm-ID: 178380  Cd Length: 315  Bit Score: 157.47  E-value: 8.07e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 201 SVLQWVLSFLVLG----VACSAILMYTFCTDCWLIAVLYFtWLAFDW----NTPKKGGRRSQWVRnwavwRYFRDYFPIQ 272
Cdd:PLN02783   15 SVLSILAVAIWLGaihfNVALVLASLFFLPSPVALTVLAL-LLLLMFipahPTSKLGRKIARFIC-----KYACAYFPVR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 273 LVKT--HNLLTTRNYIFGYHPHGIM--GLGAFCNFSTEAtevskKFPGIRPyLATLAgNFRMPVLREYLMSGGICPVNRD 348
Cdd:PLN02783   89 LHVEdeEAFDPNRAYVFGYEPHSVLpiGVIALADLSGFL-----PLPKIRA-LASSA-VFYTPFLRHIWTWLGLDPASRK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 349 TIDYLLSKngsGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPTYSFGENEVYKqvifeegsW---- 424
Cdd:PLN02783  162 NFTSLLKA---GYSCIIVPGGVQECLYMEHGSEVAYLKSRKGFVKIAMETGAPLVPVFCFGQTRAYK--------Wwkpg 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 425 GRWVQkKFQKYIGFAPCIFHGRglfssdtWGL-VPYSKPITTVVGEPITIPKLEHPTQQDIDLYHAMYMEALVKLFDKHK 503
Cdd:PLN02783  231 GPLVP-KLSRAIGFTPIVFWGR-------YGSpIPHRTPMHVVVGKPIEVKKNPQPSQEEVAEVLEQFVEALQDLFEKHK 302


                  ....*....
gi 1952711416 504 TKFGLPETE 512
Cdd:PLN02783  303 ARAGYGDLE 311
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 3-143 5.26e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.21  E-value: 5.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   3 LAIPSAQAGPRA-HAPAEALVRLHVLGVGAQE-----PRGRGGAAAERAGsspepapappgrgagwNGRPRPARVGPPGC 76
Cdd:PRK07764  362 MLLPSASDDERGlLARLERLERRLGVAGGAGApaaaaPSAAAAAPAAAPA----------------PAAAAPAAAAAPAP 425

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1952711416  77 EVIKRRAPGARAQWPPPTARFRLLLGLRRAPSPAPR-SPLPAPRAASAVPRPPTPELGAKPWPRRPGH 143
Cdd:PRK07764  426 AAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAApSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAA 493
GGN pfam15685
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the ...
 68-146 5.88e-05

Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the maturation of sperm and is expressed virtually only in the testis. It is found to be associated with the intracellular membrane, binds with GGNBP1 and may be involved in vesicular trafficking.


Pssm-ID: 434857 [Multi-domain]  Cd Length: 668  Bit Score: 45.91  E-value: 5.88e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1952711416  68 PARVGPPGCEVIKRRAPGARAQWPPPtarfrlllglrRAPSPAPRSPLPAPRAASAVpRPPTPelgakpwprRPGHGPG 146
Cdd:pfam15685 429 PVRPGPPAPQALLPRPPPPTPPATPP-----------PVPPPIPQLPALQPMPLAAA-RPPTP---------RPCPGHG 486
 
Name Accession Description Interval E-value
DAGAT pfam03982
Diacylglycerol acyltransferase; The terminal step of triacylglycerol (TAG) formation is ...
 221-517 0e+00

Diacylglycerol acyltransferase; The terminal step of triacylglycerol (TAG) formation is catalyzed by the enzyme diacylglycerol acyltransferase (DAGAT).


Pssm-ID: 112781 [Multi-domain]  Cd Length: 297  Bit Score: 519.68  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 221 MYTFCTDCWLIAVLYFTWLAFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAF 300
Cdd:pfam03982   1 FVLFFTPQWSLLVLYALWLFYDWNSPKRGGYRSNWARNWRIWKWFANYFPVKLHKTAELPPNRNYLFGYHPHGILSVGAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 301 CNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNGSGNAIIIVVGGAAESLSSMPGK 380
Cdd:pfam03982  81 SNFSTNATGFMDKFPGIRPNICTLAGQFYTPFRREILLSLGLIEVSRESIEYVLDKCGKGRAVVLVVGGAAEALEAHPGK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 381 NAVTLRNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYS 460
Cdd:pfam03982 161 HTLTLKNRKGFVRIALKTGADLVPVYSFGENDVYKQWENPEGSRLRWVQEKLKRAIGFSPPIFHGRGVFNSYTFGLLPFR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1952711416 461 KPITTVVGEPITIPKLEHPTQQDIDLYHAMYMEALVKLFDKHKTKFGLPETEVLEVN 517
Cdd:pfam03982 241 KPITTVVGAPIEVTKTLNPTQEQIDELHGQYMEALRELFEEHKTKFGVPPDTDLVLN 297
LPLAT_MGAT-like cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ...
 265-504 1.14e-51

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.


Pssm-ID: 153249 [Multi-domain]  Cd Length: 212  Bit Score: 174.78  E-value: 1.14e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 265 FRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGL-GAFCNFsteatEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGIC 343
Cdd:cd07987     1 HRKYFRVYEVRGLENIPDEGPALLVHPHGGLPIdGALLAA-----AFLLLFPGRLPRALADHFLFPLPGLRDLLRRLGAV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 344 PVNRDTIDYLLSKngsGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGS 423
Cdd:cd07987    76 PGSRENCVRLLRE---GELVLIFPGGAREALKSKREEYYLLWKKRKGFARLALRAGAPIVPVFTFGEEELFRVLGDPDGP 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 424 WGRWvqkkfqkyigfapcifHGRGLfssdtwgLVPYSKPITTVVGEPI--TIPKLEHPTQQDIDLYHAMYMEALVKLFDK 501
Cdd:cd07987   153 VGKR----------------LFRLL-------PLPRRLPLYPVFGEPIvvPRPPIPDPPDEDVEELHQKYIAALRELIEK 209


                  ...
gi 1952711416 502 HKT 504
Cdd:cd07987   210 HKK 212
PLN02783 PLN02783
diacylglycerol O-acyltransferase
 201-512 8.07e-44

diacylglycerol O-acyltransferase


Pssm-ID: 178380  Cd Length: 315  Bit Score: 157.47  E-value: 8.07e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 201 SVLQWVLSFLVLG----VACSAILMYTFCTDCWLIAVLYFtWLAFDW----NTPKKGGRRSQWVRnwavwRYFRDYFPIQ 272
Cdd:PLN02783   15 SVLSILAVAIWLGaihfNVALVLASLFFLPSPVALTVLAL-LLLLMFipahPTSKLGRKIARFIC-----KYACAYFPVR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 273 LVKT--HNLLTTRNYIFGYHPHGIM--GLGAFCNFSTEAtevskKFPGIRPyLATLAgNFRMPVLREYLMSGGICPVNRD 348
Cdd:PLN02783   89 LHVEdeEAFDPNRAYVFGYEPHSVLpiGVIALADLSGFL-----PLPKIRA-LASSA-VFYTPFLRHIWTWLGLDPASRK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 349 TIDYLLSKngsGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPTYSFGENEVYKqvifeegsW---- 424
Cdd:PLN02783  162 NFTSLLKA---GYSCIIVPGGVQECLYMEHGSEVAYLKSRKGFVKIAMETGAPLVPVFCFGQTRAYK--------Wwkpg 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416 425 GRWVQkKFQKYIGFAPCIFHGRglfssdtWGL-VPYSKPITTVVGEPITIPKLEHPTQQDIDLYHAMYMEALVKLFDKHK 503
Cdd:PLN02783  231 GPLVP-KLSRAIGFTPIVFWGR-------YGSpIPHRTPMHVVVGKPIEVKKNPQPSQEEVAEVLEQFVEALQDLFEKHK 302


                  ....*....
gi 1952711416 504 TKFGLPETE 512
Cdd:PLN02783  303 ARAGYGDLE 311
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 3-143 5.26e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.21  E-value: 5.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   3 LAIPSAQAGPRA-HAPAEALVRLHVLGVGAQE-----PRGRGGAAAERAGsspepapappgrgagwNGRPRPARVGPPGC 76
Cdd:PRK07764  362 MLLPSASDDERGlLARLERLERRLGVAGGAGApaaaaPSAAAAAPAAAPA----------------PAAAAPAAAAAPAP 425

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1952711416  77 EVIKRRAPGARAQWPPPTARFRLLLGLRRAPSPAPR-SPLPAPRAASAVPRPPTPELGAKPWPRRPGH 143
Cdd:PRK07764  426 AAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAApSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAA 493
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 6-151 2.97e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.90  E-value: 2.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   6 PSAQAGPRAHAPAEALVRLHvlGVGAQEPRGRGGAAAERAGSSPEPAPAPPGRGAGWNGRPRPARVGPPGCEVIKRRAPG 85
Cdd:PRK07764  625 AAPAPAGAAAAPAEASAAPA--PGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA 702

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1952711416  86 ARAQWPPPTArfRLLLGLRRAPSPAPRSPLPAPRAASAVPRPPTPEL-GAKPWPRRPGHGPGARGRE 151
Cdd:PRK07764  703 PAPAATPPAG--QADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDpPDPAGAPAQPPPPPAPAPA 767
GGN pfam15685
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the ...
 68-146 5.88e-05

Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the maturation of sperm and is expressed virtually only in the testis. It is found to be associated with the intracellular membrane, binds with GGNBP1 and may be involved in vesicular trafficking.


Pssm-ID: 434857 [Multi-domain]  Cd Length: 668  Bit Score: 45.91  E-value: 5.88e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1952711416  68 PARVGPPGCEVIKRRAPGARAQWPPPtarfrlllglrRAPSPAPRSPLPAPRAASAVpRPPTPelgakpwprRPGHGPG 146
Cdd:pfam15685 429 PVRPGPPAPQALLPRPPPPTPPATPP-----------PVPPPIPQLPALQPMPLAAA-RPPTP---------RPCPGHG 486
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 6-182 6.90e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 6.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   6 PSAQAGPRAHAPAEALVRLHVLGVGAQEPRGRGGAAAERAGSSPEPAPAPPGRGAGWNGRPRPARVGPPGCEViKRRAPG 85
Cdd:PRK07764  638 EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPP-AGQADD 716

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416  86 ARAQWPPPTARFRLLLGLRRAPSPAPRSP--LPAPRAASAVPRPPTPELGAKPWPRRPGHGPGARGRELQRLsmktliAA 163
Cdd:PRK07764  717 PAAQPPQAAQGASAPSPAADDPVPLPPEPddPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAED------DA 790

                         170
                  ....*....|....*....
gi 1952711416 164 YSGVLRGTGSSILSALQDL 182
Cdd:PRK07764  791 PSMDDEDRRDAEEVAMELL 809
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2-147 1.95e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.10  E-value: 1.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   2 GLAIPSAQAGPRAhAPAEALVRLHVlgvgAQEPRGRGGAAAERAGSSPEPAPAPpgrgAGWNGRPRPARVGPPGCEVIKR 81
Cdd:PRK12323  371 GAGPATAAAAPVA-QPAPAAAAPAA----AAPAPAAPPAAPAAAPAAAAAARAV----AAAPARRSPAPEALAAARQASA 441

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1952711416  82 RAPGARaqwPPPtarfrlllglrrAPSPAPrSPLPAPRAASAVPRPPTPELGAKPWPRRPGHGPGA 147
Cdd:PRK12323  442 RGPGGA---PAP------------APAPAA-APAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
4-148 3.92e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 43.30  E-value: 3.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   4 AIPSAQAGPRAHAPAEALVRLhvlGVGAQEPRGRGGAAAERAGSSPEPApappgRGAGWNGRPRPARVGPPGCEVIKRRA 83
Cdd:PRK07003  404 GAAGAALAPKAAAAAAATRAE---APPAAPAPPATADRGDDAADGDAPV-----PAKANARASADSRCDERDAQPPADSG 475

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1952711416  84 PGARAQWPPPTARFRLLLGLRRAPSPAPRSPLPAPRAASAVPRPPTPELGAKPWPRRPGHGPGAR 148
Cdd:PRK07003  476 SASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAA 540
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
31-150 4.12e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.94  E-value: 4.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416  31 AQEPRGRGGAAAERAGSspepapappgrgAGWNGRPRPARVGPPGCEVIKRRAPGARAQWPPPTARFRLLLGLRRAPSPA 110
Cdd:PRK12323  362 AFRPGQSGGGAGPATAA------------AAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPA 429

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1952711416 111 PrSPLPAPRAASAVPRP----PTPELGAKPWPRRPGHGPGARGR 150
Cdd:PRK12323  430 P-EALAAARQASARGPGgapaPAPAPAAAPAAAARPAAAGPRPV 472
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
3-145 1.22e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   3 LAIPSAQAGPRAHAPAEALVRLHVlgVGAQEPRGRGGAAAERAGSSPEPAPAPPGRGAGWNGRPRPARVGPPgcevikrr 82
Cdd:PRK12323  389 AAAPAAAAPAPAAPPAAPAAAPAA--AAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAP-------- 458

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1952711416  83 APGARAQWPPPtarfrlllglrrAPSPAPRSPLPAPRAASAVPRPptPELGAKPWPRRPGHGP 145
Cdd:PRK12323  459 AAAARPAAAGP------------RPVAAAAAAAPARAAPAAAPAP--ADDDPPPWEELPPEFA 507
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
4-147 1.35e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   4 AIPSAQAGPRAHAPAEALVRLHVLGVGAQEPRGRGGAAAERAgSSPEPAPAPPGRGAGWNGRPRPARVGPPGCEVIKRRA 83
Cdd:PRK12323  410 PAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA-PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAA 488

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1952711416  84 PGARAQWPPPtarFRLLLGLRRAPSPAPRSPLPAPRAASAVPRPPTpelgAKPWPRRPGHGPGA 147
Cdd:PRK12323  489 PAPADDDPPP---WEELPPEFASPAPAQPDAAPAGWVAESIPDPAT----ADPDDAFETLAPAP 545
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 2-148 1.72e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 1.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   2 GLAIPSAQAGPRAHAPAEALVRL-HVLGVGAQEPRGRGGAAAERAGSSPEPAPAPPGRGAGWNGRPRPARVGPPGCEVIK 80
Cdd:PRK07764  593 GAAGGEGPPAPASSGPPEEAARPaAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAK 672

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1952711416  81 RRAPGARAQWPPPTARFRLLLGLRRAPSPAPRSPLPAPRAASAVPRPPTPELGAKPWPRRPGHGPGAR 148
Cdd:PRK07764  673 AGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVP 740
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 29-151 1.99e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416  29 VGAQEPRGRGGAAAERAGSSPEPAPAPPGRGAGWNGRPRPARVGPPGCEVIKRRAPGARAQWPPPTARFRLLLGLRRAPS 108
Cdd:PRK07764  588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGD 667

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1952711416 109 PAPRSP------LPAPRAASAVPRPPTPELGAKPWPRRPGHGPGARGRE 151
Cdd:PRK07764  668 GWPAKAggaapaAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADD 716
PHA03378 PHA03378
EBNA-3B; Provisional
 2-155 2.27e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 40.82  E-value: 2.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   2 GLAIPSAQAGPRAHAPAEALVRlhvlgvgAQEPRGRGGAAAERAGS-------SPEPAPAPPGRGAGWNGRP---RPARV 71
Cdd:PHA03378  692 GTMQPPPRAPTPMRPPAAPPGR-------AQRPAAATGRARPPAAApgrarppAAAPGRARPPAAAPGRARPpaaAPGRA 764

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416  72 GPPgcevikRRAPGARAQWPPPTARFRLLLGLRRAPSPAPRsPLPAPRAASAVPRPPTPELG-AKPWPRRPGHGPGARGR 150
Cdd:PHA03378  765 RPP------AAAPGAPTPQPPPQAPPAPQQRPRGAPTPQPP-PQAGPTSMQLMPRAAPGQQGpTKQILRQLLTGGVKRGR 837


                  ....*
gi 1952711416 151 ELQRL 155
Cdd:PHA03378  838 PSLKK 842
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
28-141 7.72e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.06  E-value: 7.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416  28 GVGAQEPRGRGGAAAERAGSSPEPAPAPPGR-GAGWNGRPRPARVGPPGCEVikRRAPGARAQwPPPTARFRLLLGLRRA 106
Cdd:PRK07003  371 GVPARVAGAVPAPGARAAAAVGASAVPAVTAvTGAAGAALAPKAAAAAAATR--AEAPPAAPA-PPATADRGDDAADGDA 447

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1952711416 107 PSPAPrSPLPAPRAASAVPRPPTP----ELGAKPWPRRP 141
Cdd:PRK07003  448 PVPAK-ANARASADSRCDERDAQPpadsGSASAPASDAP 485
PHA03247 PHA03247
large tegument protein UL36; Provisional
 4-148 8.84e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.15  E-value: 8.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416    4 AIPSAQAGPRAHAPAEALVRLHVLGVGA----QEPRGRGGAAAERAGSSPEPAPAPPGRGA-----GWNGRPRPARVG-- 72
Cdd:PHA03247  2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPptvpPPERPRDDPAPGRVSRPRRARRLGRAAQAssppqRPRRRAARPTVGsl 2695

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1952711416   73 -------PPGCEVIKRRAPGARAQWPPPTARFRLLLGLRRAPSPAPRSPLPAPRAASAVPRPPTPELGAKPW----PRRP 141
Cdd:PHA03247  2696 tsladppPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPapapPAAP 2775


                   ....*..
gi 1952711416  142 GHGPGAR 148
Cdd:PHA03247  2776 AAGPPRR 2782
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH