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Conserved domains on  [gi|1953366521|ref|XP_038299671|]
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pericentrin isoform X4 [Canis lupus familiaris]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3065-3143 7.13e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


:

Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 7.13e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521 3065 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3143
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2457-3013 6.32e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 6.32e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2457 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2536
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2537 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2616
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2617 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2696
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2697 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2776
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2777 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2856
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2857 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2935
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366521 2936 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3013
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 4.60e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.37  E-value: 4.60e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  299 RTLEAQHEEALRQLREDLQSERcqyvqdLELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS 378
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELL------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  379 ARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERR 458
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  459 EQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---VV 535
Cdd:COG1196    522 LAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  536 ARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHRE 597
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  598 ELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILD 677
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|.
gi 1953366521  678 LEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    758 EPPDLEELERELERLEREIEA 778
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-1723 1.41e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 1.41e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1358 EARKQSEKDRAALlSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL--------RSQRQFMDEQAVEREHE 1429
Cdd:TIGR02168  176 ETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1430 REEFQREIQRLEEQLrqaarprphgprvsdeEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETN 1509
Cdd:TIGR02168  255 LEELTAELQELEEKL----------------EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1510 ASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQR 1589
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELES-------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1590 ESEVLDLKEQLGkmkddlvsksdevlhlnlELDAQSSRAAVSVRELQEENASLKAFLQNKEKeimcvsEQLEAQLAGMGS 1669
Cdd:TIGR02168  392 ELQIASLNNEIE------------------RLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEE 447

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366521 1670 gALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEME--QLHEVIERLQEELS 1723
Cdd:TIGR02168  448 -ELEELQEELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLE 502
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 1.97e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953366521 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1507 1.60e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 1.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAAL 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1346 RREVECL--TQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEacaKQAEELSALRQQMAALDKHLRSQRQFMDEQA 1423
Cdd:TIGR02168  827 ESLERRIaaTERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE---SELEALLNERASLEEALALLRSELEELSEEL 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1424 VEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREK-SDGFNELVIKKELADRQVMIQEEEI 1502
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRL 974


                   ....*
gi 1953366521 1503 RRLEE 1507
Cdd:TIGR02168  975 KRLEN 979
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1633-1866 1.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1633 RELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGsgALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1712
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIA--ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1713 EVIERLQEELSLGAPAVPAAVDcelpavpapavGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAEL 1792
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPE-----------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366521 1793 ERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAA 1866
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3065-3143 7.13e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 7.13e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521 3065 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3143
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2457-3013 6.32e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 6.32e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2457 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2536
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2537 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2616
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2617 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2696
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2697 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2776
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2777 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2856
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2857 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2935
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366521 2936 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3013
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 4.60e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.37  E-value: 4.60e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  299 RTLEAQHEEALRQLREDLQSERcqyvqdLELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS 378
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELL------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  379 ARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERR 458
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  459 EQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---VV 535
Cdd:COG1196    522 LAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  536 ARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHRE 597
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  598 ELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILD 677
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|.
gi 1953366521  678 LEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    758 EPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-1723 1.41e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 1.41e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1358 EARKQSEKDRAALlSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL--------RSQRQFMDEQAVEREHE 1429
Cdd:TIGR02168  176 ETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1430 REEFQREIQRLEEQLrqaarprphgprvsdeEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETN 1509
Cdd:TIGR02168  255 LEELTAELQELEEKL----------------EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1510 ASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQR 1589
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELES-------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1590 ESEVLDLKEQLGkmkddlvsksdevlhlnlELDAQSSRAAVSVRELQEENASLKAFLQNKEKeimcvsEQLEAQLAGMGS 1669
Cdd:TIGR02168  392 ELQIASLNNEIE------------------RLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEE 447

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366521 1670 gALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEME--QLHEVIERLQEELS 1723
Cdd:TIGR02168  448 -ELEELQEELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLE 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1199-1734 3.71e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.21  E-value: 3.71e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1199 QSLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGF 1278
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1279 KEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAALRREVEcLTQEQSE 1358
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE-ELEELAE 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1359 ARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQ 1438
Cdd:COG1196    387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1439 RLEEQLRQAARprpHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQ--------VMIQEEEIRRLEETNA 1510
Cdd:COG1196    467 ELLEEAALLEA---ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIGVEAAYEAALEAA 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1511 SCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcPVPPADSCPEGPEVQLEAVQRALQQRE 1590
Cdd:COG1196    544 LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARG-AIGAAVDLVASDLREADARYYVLGDTL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1591 SEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEimcvsEQLEAQLAGMGSG 1670
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL-----AERLAEEELELEE 697

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366521 1671 ALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAAVD 1734
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761
PTZ00121 PTZ00121
MAEBL; Provisional
 2466-2907 1.58e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.41  E-value: 1.58e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2466 EQEKSLEHLRASDRSSLLSEIQalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAykveQEKRIASD 2545
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVK--KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA----EEARKADE 1282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2546 VQKTltEEQEKASSVRKLLVVEQTVVRDLRSELR----ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELE 2621
Cdd:PTZ00121  1283 LKKA--EEKKKADEAKKAEEKKKADEAKKKAEEAkkadEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2622 SERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLA 2699
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKkkADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2700 QERGQLSELQRslEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvq 2779
Cdd:PTZ00121  1441 EEAKKADEAKK--KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA--- 1515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2780 KRRAELEREKEVRAAQAREPGRCLRReghaSQQQAGLEPLQAglaAQEGRKDARRADVGPGRADAEMRPTGAK--EKLRE 2857
Cdd:PTZ00121  1516 KKAEEAKKADEAKKAEEAKKADEAKK----AEEKKKADELKK---AEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKK 1588

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953366521 2858 LELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERL---QEERLGLERVRQQ 2907
Cdd:PTZ00121  1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKK 1641
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2457-2797 5.29e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.40  E-value: 5.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2457 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAqlrmthlqnqEKLQQLCAALTSAEARgsrqehqlrrqveLLAYKV 2536
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL----------ERQAEKA----------ERYKELKAELRELELA-------------LLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2537 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQdnerllaSLGEAQKEVLQLRSVLDSKESNLRAA 2616
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE-------EIEELQKELYALANEISRLEQQKQIL 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2617 LQELESergkeraLQSRLEEAQLQhLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEA 2696
Cdd:TIGR02168  308 RERLAN-------LERQLEELEAQ-LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2697 LLAQERGQLSELQRSLEAEKGRSLELAAAL-----RHERLLTEQLSRGPR-ESPAHHALLRKLKEEKSRAAELQARLEQV 2770
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLerledRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERL 459

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1953366521 2771 QRQ----QEADVQKRRAELEREKEVRAAQAR 2797
Cdd:TIGR02168  460 EEAleelREELEEAEQALDAAERELAQLQAR 490
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 1.97e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953366521 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1507 1.60e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 1.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAAL 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1346 RREVECL--TQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEacaKQAEELSALRQQMAALDKHLRSQRQFMDEQA 1423
Cdd:TIGR02168  827 ESLERRIaaTERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE---SELEALLNERASLEEALALLRSELEELSEEL 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1424 VEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREK-SDGFNELVIKKELADRQVMIQEEEI 1502
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRL 974


                   ....*
gi 1953366521 1503 RRLEE 1507
Cdd:TIGR02168  975 KRLEN 979
PTZ00121 PTZ00121
MAEBL; Provisional
 172-876 4.24e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 4.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  172 ELRAMLNGRHAQELALLRSRQQQElELAREQHAREQEEMR----LRCSQETAKLKEKLQSEMERNARAVESLKRDWESER 247
Cdd:PTZ00121  1150 DAKRVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRkaeeLRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEA 1228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  248 GLCLENLRRELSAKHRSELENLQDQFkRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQYVQDL 327
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEI-RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  328 ----ELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTPHGEELEQRErecgvqQQRRGR 403
Cdd:PTZ00121  1308 kkkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE------AKKKAD 1381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  404 RAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRvgpslqpelAENHRchltawtS 483
Cdd:PTZ00121  1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK---------AEEAK-------K 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  484 SLEAQQQAGlvETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEvvarglglEAEHRLKLLLLQTELKEEMDvl 563
Cdd:PTZ00121  1446 ADEAKKKAE--EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE--------EAKKKADEAKKAAEAKKKAD-- 1513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  564 klENRNLHEKLQHEVCLKEDLERVKHSLVEdhREELKKANErlqlVKQELKDKEAEWKVASEDlKRKAEEELTLMLHDLK 643
Cdd:PTZ00121  1514 --EAKKAEEAKKADEAKKAEEAKKADEAKK--AEEKKKADE----LKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAE 1584

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  644 EQAEAEKQSVINKFELREiKMRQLQDQQAAQildlegslvEQQGRLRQLEHGLEAEECPRCGHCGQEPAGRVAPADQdwe 723
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYE-EEKKMKAEEAKK---------AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE--- 1651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  724 laTRRLREDCALQLMQAQSRFLKERKELTEKFTAEQD------ALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRR 797
Cdd:PTZ00121  1652 --LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDekkaaeALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521  798 AEVEELKASVESERWALAEARVAELQTEHAAAISALEARHSallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA------EEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
PTZ00121 PTZ00121
MAEBL; Provisional
 1213-1877 1.86e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.93  E-value: 1.86e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1213 LDSTRQLEEARQIHSRFEKEFSCKNEET--AQVVRKQQQLLERLEEENAARTRLMLELHQAQGIiEGFKEEKASLQEALC 1290
Cdd:PTZ00121  1166 AEEARKAEDAKKAEAARKAEEVRKAEELrkAEDARKAEAARKAEEERKAEEARKAEDAKKAEAV-KKAEEAKKDAEEAKK 1244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1291 RQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEA-REAALRREVECLTQEQSEARKQSEKDRAA 1369
Cdd:PTZ00121  1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEaKKAEEKKKADEAKKKAEEAKKADEAKKKA 1324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1370 LLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQfmDEQAVEREHEREEFQREIQRLEEQLRQAAR 1449
Cdd:PTZ00121  1325 EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK--KEEAKKKADAAKKKAEEKKKADEAKKKAEE 1402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1450 PRPHGPRVSDEEQLDEEVELLQEKLREKSDGfNELVIKKELADR--QVMIQEEEIRRLEETN--ASCRREAAQLREELER 1525
Cdd:PTZ00121  1403 DKKKADELKKAAAAKKKADEAKKKAEEKKKA-DEAKKKAEEAKKadEAKKKAEEAKKAEEAKkkAEEAKKADEAKKKAEE 1481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1526 QRDAMKALQQDKEAlqEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpevQLEAVQRALQQRESEVLDLKEQLGKMKD 1605
Cdd:PTZ00121  1482 AKKADEAKKKAEEA--KKKADEAKKAAEAKKKADEAK---------------KAEEAKKADEAKKAEEAKKADEAKKAEE 1544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1606 dlVSKSDEVlhlnleLDAQSSRAAVSVRELQE-ENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIE 1684
Cdd:PTZ00121  1545 --KKKADEL------KKAEELKKAEEKKKAEEaKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE 1616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1685 ELRSIIENLRenqqrlqkeKAEEMEQLHEVIERLQEELSLGAPAVPAAVDCELPAVPAPAVGPEALAAAGAASRLFAEQE 1764
Cdd:PTZ00121  1617 EAKIKAEELK---------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1765 HRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQamaSQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAE 1844
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEE---NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764

                          650       660       670
                   ....*....|....*....|....*....|....
gi 1953366521 1845 LETILAAFSRF-RRTLERQPLAAEDEPPELQRLR 1877
Cdd:PTZ00121  1765 EEEKKAEEIRKeKEAVIEEELDEEDEKRRMEVDK 1798
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1214-1708 2.41e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.11  E-value: 2.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1214 DSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLML-------ELHQAQGIIEGFKEEKASLQ 1286
Cdd:pfam05483  258 DLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMStqkaleeDLQIATKTICQLTEEKEAQM 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1287 EALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENsalwsqkeasaaeaeareaalRREVECLTQEQSEARKQSEK- 1365
Cdd:pfam05483  338 EELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKN---------------------EDQLKIITMELQKKSSELEEm 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1366 -----DRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRL 1440
Cdd:pfam05483  397 tkfknNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDL 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1441 EEQLRQAARPRPHGPRVSDEEQLDEevellQEKLREKSDGFNELviKKELADRQVMIQEEE-----IRRLEETNASCRRE 1515
Cdd:pfam05483  477 KTELEKEKLKNIELTAHCDKLLLEN-----KELTQEASDMTLEL--KKHQEDIINCKKQEErmlkqIENLEEKEMNLRDE 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1516 AAQLREELERQRDAMKAlQQDKEALQEKQMSNLLLVSTLQSKLDEGRCpvppadscpEGPEVQLEAVQRALQQRESEVLD 1595
Cdd:pfam05483  550 LESVREEFIQKGDEVKC-KLDKSEENARSIEYEVLKKEKQMKILENKC---------NNLKKQIENKNKNIEELHQENKA 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1596 LKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSV----RELQEENASLKAFLQNKEKEIMCVSEQLEAQlagmgsga 1671
Cdd:pfam05483  620 LKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIdnyqKEIEDKKISEEKLLEEVEKAKAIADEAVKLQ-------- 691

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1953366521 1672 lREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEM 1708
Cdd:pfam05483  692 -KEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSEL 727
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 137-875 4.20e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 4.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  137 SLELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQeLALLRSRQQQELELAREQHAREQEEMRLRCSQ 216
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ-WKEKRDELNGELSAADAAVAKDRSELEALEDQ 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  217 ETAKLKEKLQSEMERNARAvESLKRDWE--SERGLCLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQA 294
Cdd:pfam12128  331 HGAFLDADIETAAADQEQL-PSWQSELEnlEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  295 ECALRTLEAQHEEALRQLREDLQSErcqyVQDLELRLRDQEVEKQLELESLRASYAEL--KAQSQEEIRRLWSQLESPRP 372
Cdd:pfam12128  410 LAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPELLlqLENFDERIERAREEQEAANA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  373 DRQDAsartphgeeleQRERecgvqQQRRGRRAEQESELGQSPEGAAERgredpvllEQRLQDATEEPSLESGGIGPSSM 452
Cdd:pfam12128  486 EVERL-----------QSEL-----RQARKRRDQASEALRQASRRLEER--------QSALDELELQLFPQAGTLLHFLR 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  453 REGERREQRVGPSLQPELAenHRCHLTAwtssleaqqqaglVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDT 532
Cdd:pfam12128  542 KEAPDWEQSIGKVISPELL--HRTDLDP-------------EVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  533 EVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLEnrnlheklqhevclkedLERVKHSLvEDHREELKKANERLQLVKQE 612
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASRE-----------------ETFARTAL-KNARLDLRRLFDEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  613 LKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQsvinkfELREIKMRQLQDQQAaqildLEGSLVEQQGRLRQL 692
Cdd:pfam12128  669 KNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKE------QKREARTEKQAYWQV-----VEGALDAQLALLKAA 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  693 EHGLEAEECPRCGHCGQEPAGRVAPADQDWELATRRLREdcALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKHAc 772
Cdd:pfam12128  738 IAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKRE--IRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLAT- 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  773 dmrlLQERHQQHVLSLTAQLeARRRAEVEELKASVESERWAL--AEARVAELQTEHAAAISALEARHSALLGSLESRHLS 850
Cdd:pfam12128  815 ----QLSNIERAISELQQQL-ARLIADTKLRRAKLEMERKASekQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIG 889

                          730       740
                   ....*....|....*....|....*
gi 1953366521  851 EVQAMREEHRQALEQLRVDLEKQLQ 875
Cdd:pfam12128  890 ERLAQLEDLKLKRDYLSESVKKYVE 914
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2469-2897 2.01e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 2.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2469 KSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRR-----------QVELLAYKVE 2537
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAledqhgafldaDIETAAADQE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2538 QEKRIASDVQ------KTLTEEQ---EKASSVRKLLVVEQ--TVVRDLRSELRECKQDNERLLASL-GEAQKEVLQLRSV 2605
Cdd:pfam12128  348 QLPSWQSELEnleerlKALTGKHqdvTAKYNRRRSKIKEQnnRDIAGIKDKLAKIREARDRQLAVAeDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2606 LDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREgQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK 2685
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLE-NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASE 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2686 ELQieasRCEALLAQERGQLSELQRSLEAEKGRSLE----------------LAAALRHERLLTEQLSRGPR-------- 2741
Cdd:pfam12128  507 ALR----QASRRLEERQSALDELELQLFPQAGTLLHflrkeapdweqsigkvISPELLHRTDLDPEVWDGSVggelnlyg 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2742 --------ESPAHHALLRKLKEEKSRAAE-LQARLEQVQRQQEADVQKRRA-ELEREKEVRAAQAREPGRcLRREGHASQ 2811
Cdd:pfam12128  583 vkldlkriDVPEWAASEEELRERLDKAEEaLQSAREKQAAAEEQLVQANGElEKASREETFARTALKNAR-LDLRRLFDE 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2812 QQAGLEPLQAGLAAQEGRKDARRADVgpgraDAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEA 2891
Cdd:pfam12128  662 KQSEKDKKNKALAERKDSANERLNSL-----EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA 736


                   ....*.
gi 1953366521 2892 ERLQEE 2897
Cdd:pfam12128  737 AIAARR 742
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 169-439 3.21e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 3.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  169 ALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAvESLKRDWESERG 248
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-EQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  249 LcLENLRRELSAKHRsELENLqdqfKRELSEQKAELEKIFQAKNQAECALRTLEAQ-HEEALRQLREDLQSERcQYVQDL 327
Cdd:TIGR02169  738 R-LEELEEDLSSLEQ-EIENV----KSELKELEARIEELEEDLHKLEEALNDLEARlSHSRIPEIQAELSKLE-EEVSRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  328 ELRLrdQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS----------ARTPHGEELEQRERECGVQ 397
Cdd:TIGR02169  811 EARL--REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLngkkeeleeeLEELEAALRDLESRLGDLK 888

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1953366521  398 QQRRGRRA---EQESELGQSpEGAAERGREDPVLLEQRLQDATEE 439
Cdd:TIGR02169  889 KERDELEAqlrELERKIEEL-EAQIEKKRKRLSELKAKLEALEEE 932
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1633-1866 1.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1633 RELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGsgALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1712
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIA--ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1713 EVIERLQEELSLGAPAVPAAVDcelpavpapavGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAEL 1792
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPE-----------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366521 1793 ERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAA 1866
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3065-3143 7.13e-26

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 103.06  E-value: 7.13e-26
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521 3065 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAdkkTTTSRPFTRFRTAVRVVIAILRLRFLVKKW 3143
Cdd:pfam10495    2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD---RPSRKPRRKLKSAALAVIAIARMKRLAREW 77
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2457-3013 6.32e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 6.32e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2457 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAQlRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVELLAYKV 2536
Cdd:COG1196    188 LERLEDILGELERQLEPL----------ERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELE-ELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2537 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAA 2616
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2617 LQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLcVALKHEQTAKDNLQKELQIEASRCEA 2696
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2697 LLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEA 2776
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE------EEEALLELLAELLEEAALLEAALAELLEELAE 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2777 DVQKRRAELEREKEVRAaqarepgrclRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKeklR 2856
Cdd:COG1196    489 AAARLLLLLEAEADYEG----------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE---D 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2857 ELELQRQRDEHKIRQLQR-TVQALEAKEEAAQRPEAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNE 2935
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRaTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366521 2936 KAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRR 3013
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2452-2909 1.67e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.38  E-value: 1.67e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2452 EHSSLLERLEKVVQEQEKSLEHLRAS--DRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2529
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLEleELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2530 ELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSvLDSK 2609
Cdd:COG1196    330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-LEEA 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2610 ESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQI 2689
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2690 EASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQ 2769
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2770 -----VQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAA--------QEGRKDARRAD 2836
Cdd:COG1196    569 akagrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAarleaalrRAVTLAGRLRE 648

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953366521 2837 VGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQQLL 2909
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 139-698 4.60e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.37  E-value: 4.60e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  139 ELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLrcsQET 218
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---AEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  219 AKLKEKLQSEMERNARAVESLKRdweserglclENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEE----------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  299 RTLEAQHEEALRQLREDLQSERcqyvqdLELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS 378
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELL------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  379 ARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERR 458
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  459 EQRVGPSLQPELAEnhrcHLTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTE---VV 535
Cdd:COG1196    522 LAGAVAVLIGVEAA----YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALargAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  536 ARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERV------------------KHSLVEDHRE 597
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVtlegeggsaggsltggsrRELLAALLEA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  598 ELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILD 677
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          570       580
                   ....*....|....*....|.
gi 1953366521  678 LEGSLVEQQGRLRQLEHGLEA 698
Cdd:COG1196    758 EPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-1723 1.41e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 1.41e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1358 EARKQSEKDRAALlSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL--------RSQRQFMDEQAVEREHE 1429
Cdd:TIGR02168  176 ETERKLERTRENL-DRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1430 REEFQREIQRLEEQLrqaarprphgprvsdeEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETN 1509
Cdd:TIGR02168  255 LEELTAELQELEEKL----------------EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1510 ASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQR 1589
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELES-------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1590 ESEVLDLKEQLGkmkddlvsksdevlhlnlELDAQSSRAAVSVRELQEENASLKAFLQNKEKeimcvsEQLEAQLAGMGS 1669
Cdd:TIGR02168  392 ELQIASLNNEIE------------------RLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEE 447

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366521 1670 gALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEME--QLHEVIERLQEELS 1723
Cdd:TIGR02168  448 -ELEELQEELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLE 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1199-1734 3.71e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.21  E-value: 3.71e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1199 QSLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGF 1278
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1279 KEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAALRREVEcLTQEQSE 1358
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE-ELEELAE 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1359 ARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQ 1438
Cdd:COG1196    387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1439 RLEEQLRQAARprpHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQ--------VMIQEEEIRRLEETNA 1510
Cdd:COG1196    467 ELLEEAALLEA---ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIGVEAAYEAALEAA 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1511 SCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcPVPPADSCPEGPEVQLEAVQRALQQRE 1590
Cdd:COG1196    544 LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARG-AIGAAVDLVASDLREADARYYVLGDTL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1591 SEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEimcvsEQLEAQLAGMGSG 1670
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL-----AERLAEEELELEE 697

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366521 1671 ALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAAVD 1734
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1354-1890 1.59e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.59e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1354 QEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSA----LRQQMAALDK---HLRSQRQFMDEQAVER 1426
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyeLLAELARLEQdiaRLEERRRELEERLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1427 EHEREE-------FQREIQRLEEQLRQAARPRPHgpRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQE 1499
Cdd:COG1196    322 EEELAEleeeleeLEEELEELEEELEEAEEELEE--AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1500 EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGrcpvppadscpegpEVQL 1579
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL--------------LELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1580 EAVQRALQQRESEVLDLKEQLGKmkddlvSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQ 1659
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1660 LEAQLAGMGSGALREVTYDRSSEIEEL------RSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAAV 1733
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLkaakagRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1734 D--CELPAVPAPAVGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMA-SQI 1810
Cdd:COG1196    620 DtlLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELeEAL 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1811 QAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRLSRQLQVL 1890
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 2466-2907 1.58e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.41  E-value: 1.58e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2466 EQEKSLEHLRASDRSSLLSEIQalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAykveQEKRIASD 2545
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVK--KAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA----EEARKADE 1282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2546 VQKTltEEQEKASSVRKLLVVEQTVVRDLRSELR----ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELE 2621
Cdd:PTZ00121  1283 LKKA--EEKKKADEAKKAEEKKKADEAKKKAEEAkkadEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2622 SERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLA 2699
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKkkADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2700 QERGQLSELQRslEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvq 2779
Cdd:PTZ00121  1441 EEAKKADEAKK--KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA--- 1515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2780 KRRAELEREKEVRAAQAREPGRCLRReghaSQQQAGLEPLQAglaAQEGRKDARRADVGPGRADAEMRPTGAK--EKLRE 2857
Cdd:PTZ00121  1516 KKAEEAKKADEAKKAEEAKKADEAKK----AEEKKKADELKK---AEELKKAEEKKKAEEAKKAEEDKNMALRkaEEAKK 1588

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953366521 2858 LELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERL---QEERLGLERVRQQ 2907
Cdd:PTZ00121  1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKK 1641
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2457-2797 5.29e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.40  E-value: 5.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2457 LERLEKVVQEQEKSLEHLrasdrssllsEIQALRAqlrmthlqnqEKLQQLCAALTSAEARgsrqehqlrrqveLLAYKV 2536
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL----------ERQAEKA----------ERYKELKAELRELELA-------------LLVLRL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2537 EQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQdnerllaSLGEAQKEVLQLRSVLDSKESNLRAA 2616
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE-------EIEELQKELYALANEISRLEQQKQIL 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2617 LQELESergkeraLQSRLEEAQLQhLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEA 2696
Cdd:TIGR02168  308 RERLAN-------LERQLEELEAQ-LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2697 LLAQERGQLSELQRSLEAEKGRSLELAAAL-----RHERLLTEQLSRGPR-ESPAHHALLRKLKEEKSRAAELQARLEQV 2770
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLerledRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERL 459

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1953366521 2771 QRQ----QEADVQKRRAELEREKEVRAAQAR 2797
Cdd:TIGR02168  460 EEAleelREELEEAEQALDAAERELAQLQAR 490
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1255-1914 8.41e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 8.41e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1255 EEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALwSQKEAS 1334
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL-ANEISR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1335 AAEAEAREAALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRS 1414
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1415 QRQFMDEQAVEREHEREEFQREIQRLEEQLRQAA--RPRPHGPRVSDEEQLDE-EVELLQEKLREKSDGFNELVIKKELA 1491
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEdrRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1492 DRQVMIQEEEIRRLEETNASCRREAAQLREELerqrDAMKALQQDKEALQEkQMSNLLLVstlQSKLDEGRCPVPPADSC 1571
Cdd:TIGR02168  460 EEALEELREELEEAEQALDAAERELAQLQARL----DSLERLQENLEGFSE-GVKALLKN---QSGLSGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1572 PEGPEVQLEAVqralqqresevldlkeqLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVREL-----QEENASLKAFL 1646
Cdd:TIGR02168  532 DEGYEAAIEAA-----------------LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLdsikgTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1647 QNKE------KEIMCVSEQLEAQLAGMGSGAL-------------------REVTYD----------------RSSEIEE 1685
Cdd:TIGR02168  595 KNIEgflgvaKDLVKFDPKLRKALSYLLGGVLvvddldnalelakklrpgyRIVTLDgdlvrpggvitggsakTNSSILE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1686 LRSIIENLRENQQRLQkekaEEMEQLHEVIERLQEELSLGAPAVPAAVDCELPAVPAPAVGPEALAAAGAASRLFAEQEH 1765
Cdd:TIGR02168  675 RRREIEELEEKIEELE----EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1766 RHGQALEALQQRLQAAEEAAAGQLAELERSAALR---EAEVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHS 1842
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIeelEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953366521 1843 AELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRLSRQLQVLnqrflrcQKEADKQQARGARLRPR 1914
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL-------LNERASLEEALALLRSE 895
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1245-1815 1.57e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1245 RKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEEN 1324
Cdd:COG1196    239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1325 SALwsqkeasaaeaEAREAALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQ 1404
Cdd:COG1196    319 EEL-----------EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1405 MAALDKHLRSQRQfmdeQAVEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREKSDGFNEL 1484
Cdd:COG1196    388 LLEALRAAAELAA----QLEELEEAEEALLERLERLEEELEELEE---------ALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1485 VIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQ-DKEALQEKQMSNLLLVSTLQSKLDEGRC 1563
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGfLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1564 PVPPADSCPEGPEVQLEAVQRALQQRESEVLDLKEQLGKM----------------KDDLVSKSDEVLHLNLELDAQSSR 1627
Cdd:COG1196    535 AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflpldkiraraalaaALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1628 AAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEE 1707
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1708 MEQLHEVIERLQEELSLGApavpaavdcelpavpapavgpEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAG 1787
Cdd:COG1196    695 LEEALLAEEEEERELAEAE---------------------EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753

                          570       580
                   ....*....|....*....|....*...
gi 1953366521 1788 QLAELERSAALREAEVQAMASQIQAFEA 1815
Cdd:COG1196    754 EELPEPPDLEELERELERLEREIEALGP 781
PTZ00121 PTZ00121
MAEBL; Provisional
 2515-2898 1.86e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2515 EARGSRQEHQLRRQVELLAYKVEqEKRIASDVQKTLTEEQEKASSVRKllvveQTVVRDLRSELRECKQDNERLLASLGE 2594
Cdd:PTZ00121  1458 KAEEAKKKAEEAKKADEAKKKAE-EAKKADEAKKKAEEAKKKADEAKK-----AAEAKKKADEAKKAEEAKKADEAKKAE 1531

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2595 AQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQlcvALK 2674
Cdd:PTZ00121  1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK---KMK 1608

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2675 HEQTAKDNLQKELQIEASRCEallaQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLK 2754
Cdd:PTZ00121  1609 AEEAKKAEEAKIKAEELKKAE----EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2755 EEKSRAAELQAR-------LEQVQRQQEADVQKRRaELEREKEVRAAQAREpgrcLRREGHASQQQagleplqaglaAQE 2827
Cdd:PTZ00121  1685 EDEKKAAEALKKeaeeakkAEELKKKEAEEKKKAE-ELKKAEEENKIKAEE----AKKEAEEDKKK-----------AEE 1748

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953366521 2828 GRKDarradvgpgradaemrpTGAKEKLRELELQRQRDEHKIRQLQRTVqaleAKEEAAQRPEAERLQEER 2898
Cdd:PTZ00121  1749 AKKD-----------------EEEKKKIAHLKKEEEKKAEEIRKEKEAV----IEEELDEEDEKRRMEVDK 1798
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 566-1066 1.97e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  566 ENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAE--EELTLMLHDLK 643
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEErlEELEEELAELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  644 EQAEAEKQSVINKfELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcgqepAGRVAPADQDWE 723
Cdd:COG1196    330 EELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA-----------EELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  724 LATRRLREDCALQ-LMQAQSRFLKERKELTEKFTAEQDAL--LQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEV 800
Cdd:COG1196    398 LAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  801 EELKASVESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEAS 880
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  881 HPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQ 960
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  961 LHCQEEPEVLECPSEPFLEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQIL 1040
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          490       500
                   ....*....|....*....|....*.
gi 1953366521 1041 SLSHEVEERRRDLEQLQQRRERENQE 1066
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2455-3018 2.78e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 2.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2455 SLLERLEKVvQEQEKSLEHLRASdRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAY 2534
Cdd:TIGR02168  236 ELREELEEL-QEELKEAEEELEE-LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2535 KVEQEKRIASD---VQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKE- 2610
Cdd:TIGR02168  314 LERQLEELEAQleeLESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEl 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2611 ---------SNLRAALQELESERGKER----ALQSRLEEAQLQHLQRE-GQSSKTLEELRASLEKQFAQSSQLCVALKHE 2676
Cdd:TIGR02168  394 qiaslnneiERLEARLERLEDRRERLQqeieELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2677 QTAKDNLQKELQIEASRCEALLAQER--------------------GQLSELQRSLEAEKGRSLELAAALRhERLL---- 2732
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQEnlegfsegvkallknqsglsGILGVLSELISVDEGYEAAIEAALG-GRLQavvv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2733 -TEQLSRGPRESPAHHALLRK--LKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHA 2809
Cdd:TIGR02168  553 eNLNAAKKAIAFLKQNELGRVtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2810 S-QQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQr 2888
Cdd:TIGR02168  633 NaLELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE- 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2889 peaERLQEERLGLERVRQQLLCAAGLLTSFisRTVDRTISDWTSSNEKAVTSLLHTLEELKSELSTPSSSQKKMTAELQT 2968
Cdd:TIGR02168  712 ---EELEQLRKELEELSRQISALRKDLARL--EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1953366521 2969 --QLVDVLLKDNDSLTKALRTVTQEKAELCRAVSQLEKSLKHHVLRRGVCSK 3018
Cdd:TIGR02168  787 leAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1408-1720 5.27e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 5.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1408 LDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAArprphgprvSDEEQLDEEVELLQEKLREKSDGFNELVIK 1487
Cdd:TIGR02168  650 LDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELE---------EKIAELEKALAELRKELEELEEELEQLRKE 720

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1488 KELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRCPVPP 1567
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1568 ADScpegpevQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEvlhlNLELDAQSSRAAVSVRELQEENASLKAFLQ 1647
Cdd:TIGR02168  801 LRE-------ALDELRAELTLLNEEAANLRERLESLERRIAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953366521 1648 NKEKEIMCVSEQLEAQLAGMGSgalrevtydRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQE 1720
Cdd:TIGR02168  870 ELESELEALLNERASLEEALAL---------LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2416-2881 6.32e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 6.32e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2416 LDWRGEFLQAVQEAFGKEREMLRAELQprpcgsapgEHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRm 2495
Cdd:COG1196    321 LEEELAELEEELEELEEELEELEEELE---------EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE- 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2496 tHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLR 2575
Cdd:COG1196    391 -ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2576 SELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAAL------------QELESERGKERALQSRLEEAQLQHLQ 2643
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKaalllaglrglaGAVAVLIGVEAAYEAALEAALAAALQ 549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2644 REG-QSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLEL 2722
Cdd:COG1196    550 NIVvEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2723 AAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRC 2802
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521 2803 LRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELelqrqrdEHKIRQLQRTVQALEA 2881
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL-------ERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2575-2896 6.40e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 6.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2575 RSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQ---SRLEEAQLQHLQREGQSSKT 2651
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2652 LEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQieasRCEALLAQERGQLSELQRSLEAEKGRSLElaaalrherl 2731
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----QLKEELKALREALDELRAELTLLNEEAAN---------- 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2732 LTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQ 2811
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2812 QQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRE---------------LELQRQRDEHKIRQLQRTV 2876
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeysltleeaealenkIEDDEEEARRRLKRLENKI 981

                          330       340
                   ....*....|....*....|....*
gi 1953366521 2877 QA-----LEAKEEAAQrpEAERLQE 2896
Cdd:TIGR02168  982 KElgpvnLAAIEEYEE--LKERYDF 1004
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2455-2798 1.28e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 1.28e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2455 SLLERLEKVvQEQEKSLEHLRAS---DRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEhQLRRQVEL 2531
Cdd:TIGR02169  671 SEPAELQRL-RERLEGLKRELSSlqsELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE-ELEEDLSS 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2532 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLvvEQTVVRDLRSELREckqdnerLLASLGEAQKEVLQLRSVLDSKES 2611
Cdd:TIGR02169  749 LEQEIENVKSELKELEARIEELEEDLHKLEEAL--NDLEARLSHSRIPE-------IQAELSKLEEEVSRIEARLREIEQ 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2612 NLRAALQELESERGKERALQSRLEEAQLQHLQREGQ---SSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK--- 2685
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEienLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAqlr 899

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2686 ELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELaaalrherlltEQLSRGPRESPAHHALLRKLKEEKSRAAELQA 2765
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI-----------EDPKGEDEEIPEEELSLEDVQAELQRVEEEIR 968

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1953366521 2766 RLEQVQR---QQEADVQKRRAELEREKEVRAAQARE 2798
Cdd:TIGR02169  969 ALEPVNMlaiQEYEEVLKRLDELKEKRAKLEEERKA 1004
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1186-1507 1.60e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 1.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1186 SSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLM 1265
Cdd:TIGR02168  671 SILERRREIEE----LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAAL 1345
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1346 RREVECL--TQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEacaKQAEELSALRQQMAALDKHLRSQRQFMDEQA 1423
Cdd:TIGR02168  827 ESLERRIaaTERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE---SELEALLNERASLEEALALLRSELEELSEEL 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1424 VEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREK-SDGFNELVIKKELADRQVMIQEEEI 1502
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRL 974


                   ....*
gi 1953366521 1503 RRLEE 1507
Cdd:TIGR02168  975 KRLEN 979
PTZ00121 PTZ00121
MAEBL; Provisional
 2452-2906 1.68e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.39  E-value: 1.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2452 EHSSLLERLEKVVQEQEKSLEHLRA-SDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAE---ARGSRQEHQLRR 2527
Cdd:PTZ00121  1312 EEAKKADEAKKKAEEAKKKADAAKKkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAkkkADAAKKKAEEKK 1391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2528 QVELLAYKVEQEKRIASDVQKTlTEEQEKASSVRKLlVVEQTVVRDLRSELRECKQDNErlLASLGEAQKEVLQLRSvlD 2607
Cdd:PTZ00121  1392 KADEAKKKAEEDKKKADELKKA-AAAKKKADEAKKK-AEEKKKADEAKKKAEEAKKADE--AKKKAEEAKKAEEAKK--K 1465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2608 SKESNLRAALQELESERGKERALQSRLEEAQ--LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK 2685
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2686 ELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERLLTEQLSRGPRESpahhallRKLKEEKSRAA-EL 2763
Cdd:PTZ00121  1546 KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaEEARIEEVMKLYEEE-------KKMKAEEAKKAeEA 1618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2764 QARLEQVQRQQEADVQKRRAELEREKEVRAAQ---AREPGRCLRREGHASQQQAGLEPLQAGLAAQEGRKDARRA---DV 2837
Cdd:PTZ00121  1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEelkKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAlkkEA 1698

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953366521 2838 GPGRADAEMRPTGAKEKLRELELQRQRDEHKIR--QLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQ 2906
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
PTZ00121 PTZ00121
MAEBL; Provisional
 172-876 4.24e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 4.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  172 ELRAMLNGRHAQELALLRSRQQQElELAREQHAREQEEMR----LRCSQETAKLKEKLQSEMERNARAVESLKRDWESER 247
Cdd:PTZ00121  1150 DAKRVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRkaeeLRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEA 1228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  248 GLCLENLRRELSAKHRSELENLQDQFkRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQYVQDL 327
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEI-RKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  328 ----ELRLRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTPHGEELEQRErecgvqQQRRGR 403
Cdd:PTZ00121  1308 kkkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE------AKKKAD 1381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  404 RAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRvgpslqpelAENHRchltawtS 483
Cdd:PTZ00121  1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK---------AEEAK-------K 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  484 SLEAQQQAGlvETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEvvarglglEAEHRLKLLLLQTELKEEMDvl 563
Cdd:PTZ00121  1446 ADEAKKKAE--EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE--------EAKKKADEAKKAAEAKKKAD-- 1513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  564 klENRNLHEKLQHEVCLKEDLERVKHSLVEdhREELKKANErlqlVKQELKDKEAEWKVASEDlKRKAEEELTLMLHDLK 643
Cdd:PTZ00121  1514 --EAKKAEEAKKADEAKKAEEAKKADEAKK--AEEKKKADE----LKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAE 1584

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  644 EQAEAEKQSVINKFELREiKMRQLQDQQAAQildlegslvEQQGRLRQLEHGLEAEECPRCGHCGQEPAGRVAPADQdwe 723
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYE-EEKKMKAEEAKK---------AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE--- 1651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  724 laTRRLREDCALQLMQAQSRFLKERKELTEKFTAEQD------ALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRR 797
Cdd:PTZ00121  1652 --LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDekkaaeALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521  798 AEVEELKASVESERWALAEARVAELQTEHAAAISALEARHSallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA------EEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1219-1896 8.09e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 8.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1219 LEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQ-------AQGIIEGFKEEKASLQEALCR 1291
Cdd:TIGR02168  290 LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEleekleeLKEELESLEAELEELEAELEE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1292 QETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKeasaaeaeareAALRREVECLTQEQSEARKQ-SEKDRAAL 1370
Cdd:TIGR02168  370 LESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL-----------ERLEDRRERLQQEIEELLKKlEEAELKEL 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1371 LSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARP 1450
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1451 RPHGPRVSDEEQLDEEVEL-LQEKLREKSDgfNELVIKKELADRQVMIQEE-EIRR---LEETNASCRREAAQLREELER 1525
Cdd:TIGR02168  519 SGILGVLSELISVDEGYEAaIEAALGGRLQ--AVVVENLNAAKKAIAFLKQnELGRvtfLPLDSIKGTEIQGNDREILKN 596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1526 QRDAMKALQQDKEALQEKQ------MSNLLLVSTLQSKLD-------EGRCPVPPADSCPEGPEVQLEAVQRA--LQQRE 1590
Cdd:TIGR02168  597 IEGFLGVAKDLVKFDPKLRkalsylLGGVLVVDDLDNALElakklrpGYRIVTLDGDLVRPGGVITGGSAKTNssILERR 676

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1591 SEVLDLKEQLGKMKDDLvsksdevlhlnLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAqlAGMGSG 1670
Cdd:TIGR02168  677 REIEELEEKIEELEEKI-----------AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR--LEAEVE 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1671 ALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAE---EMEQLHEVIERLQEELSLgapavpaavdcelpavpapavgp 1747
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA----------------------- 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1748 EALAAAGAASRLFAEQEHRHGQALEalQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAALRAKEARLAER 1827
Cdd:TIGR02168  801 LREALDELRAELTLLNEEAANLRER--LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521 1828 DLEIDAMKRQKLAHSAELETilaaFSRFRRTLERQPLAAEDeppELQRLRVQCVRLSRQLQVLNQRFLR 1896
Cdd:TIGR02168  879 LNERASLEEALALLRSELEE----LSEELRELESKRSELRR---ELEELREKLAQLELRLEGLEVRIDN 940
PTZ00121 PTZ00121
MAEBL; Provisional
 2405-2905 1.14e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 1.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2405 QKGEQEPPDPGLDWRGEFLQAVQEAFGKEREMLRAELQPRPCGSAPGEHSSLLERLEKVvqEQEKSLEHLRASDRSSLLS 2484
Cdd:PTZ00121  1096 AFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRV--EIARKAEDARKAEEARKAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2485 EIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEhqlRRQVEllAYKVEQEKRI-----ASDVQKTlTEEQEKASS 2559
Cdd:PTZ00121  1174 DAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEE---RKAEE--ARKAEDAKKAeavkkAEEAKKD-AEEAKKAEE 1247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2560 VRKLLVVEQTVVRDLRSELR--------------ECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRA--ALQELESE 2623
Cdd:PTZ00121  1248 ERNNEEIRKFEEARMAHFARrqaaikaeearkadELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEA 1327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2624 RGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAllaQERG 2703
Cdd:PTZ00121  1328 KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA---EEDK 1404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2704 QLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHAllRKLKEEKSRAAELQARLEQVQRQQEADVQKRRA 2783
Cdd:PTZ00121  1405 KKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA--KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA 1482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2784 ELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAAQEGRK--DARRADvgpgradaEMRPTGAKEKLRELelq 2861
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaeEAKKAD--------EAKKAEEKKKADEL--- 1551

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1953366521 2862 rqRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVR 2905
Cdd:PTZ00121  1552 --KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1410-1722 1.34e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.23  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1410 KHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAAR-----PRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNEL 1484
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKeleelSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1485 VIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRCP 1564
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1565 VppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSR---AAVSVRELQEENAS 1641
Cdd:TIGR02168  840 L-------EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEleeLSEELRELESKRSE 912

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1642 LKAFLQNKEKEImcvsEQLEAQLAGMGSgalrevtydrsseieELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEE 1721
Cdd:TIGR02168  913 LRRELEELREKL----AQLELRLEGLEV---------------RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR 973


                   .
gi 1953366521 1722 L 1722
Cdd:TIGR02168  974 L 974
PTZ00121 PTZ00121
MAEBL; Provisional
 1213-1877 1.86e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.93  E-value: 1.86e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1213 LDSTRQLEEARQIHSRFEKEFSCKNEET--AQVVRKQQQLLERLEEENAARTRLMLELHQAQGIiEGFKEEKASLQEALC 1290
Cdd:PTZ00121  1166 AEEARKAEDAKKAEAARKAEEVRKAEELrkAEDARKAEAARKAEEERKAEEARKAEDAKKAEAV-KKAEEAKKDAEEAKK 1244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1291 RQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEA-REAALRREVECLTQEQSEARKQSEKDRAA 1369
Cdd:PTZ00121  1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEaKKAEEKKKADEAKKKAEEAKKADEAKKKA 1324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1370 LLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQfmDEQAVEREHEREEFQREIQRLEEQLRQAAR 1449
Cdd:PTZ00121  1325 EEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK--KEEAKKKADAAKKKAEEKKKADEAKKKAEE 1402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1450 PRPHGPRVSDEEQLDEEVELLQEKLREKSDGfNELVIKKELADR--QVMIQEEEIRRLEETN--ASCRREAAQLREELER 1525
Cdd:PTZ00121  1403 DKKKADELKKAAAAKKKADEAKKKAEEKKKA-DEAKKKAEEAKKadEAKKKAEEAKKAEEAKkkAEEAKKADEAKKKAEE 1481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1526 QRDAMKALQQDKEAlqEKQMSNLLLVSTLQSKLDEGRcpvppadscpegpevQLEAVQRALQQRESEVLDLKEQLGKMKD 1605
Cdd:PTZ00121  1482 AKKADEAKKKAEEA--KKKADEAKKAAEAKKKADEAK---------------KAEEAKKADEAKKAEEAKKADEAKKAEE 1544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1606 dlVSKSDEVlhlnleLDAQSSRAAVSVRELQE-ENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIE 1684
Cdd:PTZ00121  1545 --KKKADEL------KKAEELKKAEEKKKAEEaKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE 1616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1685 ELRSIIENLRenqqrlqkeKAEEMEQLHEVIERLQEELSLGAPAVPAAVDCELPAVPAPAVGPEALAAAGAASRLFAEQE 1764
Cdd:PTZ00121  1617 EAKIKAEELK---------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1765 HRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQamaSQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAE 1844
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEE---NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764

                          650       660       670
                   ....*....|....*....|....*....|....
gi 1953366521 1845 LETILAAFSRF-RRTLERQPLAAEDEPPELQRLR 1877
Cdd:PTZ00121  1765 EEEKKAEEIRKeKEAVIEEELDEEDEKRRMEVDK 1798
PTZ00121 PTZ00121
MAEBL; Provisional
 165-700 4.44e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 4.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  165 EKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWE 244
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  245 SERGLCL---ENLRRELSAKHRSELENLQDQFKRELSEQKAELEkifQAKNQAECALRTLEAQHEEALRQLREDLQSERC 321
Cdd:PTZ00121  1289 KKKADEAkkaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD---AAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  322 QYVQDL---ELRLRDQEVEKQLElESLRASYAELKAqsqEEIRRLWSQLESPRPDRQDASARTPHGEELEQ-RERECGVQ 397
Cdd:PTZ00121  1366 AEAAEKkkeEAKKKADAAKKKAE-EKKKADEAKKKA---EEDKKKADELKKAAAAKKKADEAKKKAEEKKKaDEAKKKAE 1441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  398 QQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGErrEQRVGPSLQPELAENHRCH 477
Cdd:PTZ00121  1442 EAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAD--EAKKAAEAKKKADEAKKAE 1519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  478 LTAWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEVV-----ARGLGLEAEHRLKLLLL 552
Cdd:PTZ00121  1520 EAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNmalrkAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  553 QTELKEEMDVLKL----ENRNLHEKLQHEVCLKEDLERVKHSLVEDHR--EELKKANERLQLVKQELKDKEAEWKVASED 626
Cdd:PTZ00121  1600 LYEEEKKMKAEEAkkaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKkaEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366521  627 LKRKAEEELTLMLHDLKEQAEAEKQSVINKFELREI-KMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEE 700
Cdd:PTZ00121  1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE 1754
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2463-2788 4.55e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 4.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2463 VVQEQEKSLEHLRAsDRSSLLSEIQALRAQLRMTHLQNQEKLQQLcAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRI 2542
Cdd:TIGR02168  671 SILERRREIEELEE-KIEELEEKIAELEKALAELRKELEELEEEL-EQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2543 ASDVQKTLTEEQEKASSVRKLLvveqtvvRDLRSELRECKQDNERLLASLGEAQKEVLQLRSvldskesnlraALQELES 2622
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERL-------EEAEEELAEAEAEIEELEAQIEQLKEELKALRE-----------ALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2623 ERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQI---EASRCEALLA 2699
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllnERASLEEALA 890

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2700 QERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPREspahhaLLRKLKEEKSRAAELQARLEQVQRQQEADVQ 2779
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG------LEVRIDNLQERLSEEYSLTLEEAEALENKIE 964


                   ....*....
gi 1953366521 2780 KRRAELERE 2788
Cdd:TIGR02168  965 DDEEEARRR 973
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1349-1722 9.53e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.15  E-value: 9.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1349 VECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSqrqfMDEQAVEREH 1428
Cdd:PRK03918   191 IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRK----LEEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1429 EREEFQREIQRLEEQLRqaarprphgpRVSDEEQLDEEVELLQEKLREKSDGFNElvIKKELADRQVMIQ--EEEIRRLE 1506
Cdd:PRK03918   267 RIEELKKEIEELEEKVK----------ELKELKEKAEEYIKLSEFYEEYLDELRE--IEKRLSRLEEEINgiEERIKELE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1507 ETNascrREAAQLREELERQRDAMKALQQDKEALQEkqmsnlllVSTLQSKLDEGRCPVppADSCPEGPEVQLEAVQRAL 1586
Cdd:PRK03918   335 EKE----ERLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRL--TGLTPEKLEKELEELEKAK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1587 QQRESEVLDLKEQLGKMKDDLVSKSDEVlhlnLELDAQSSRAAVSVRELQEEN-----ASLKAFLQNKEKEIMCVSEQLE 1661
Cdd:PRK03918   401 EEIEEEISKITARIGELKKEIKELKKAI----EELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKELKEIEEKER 476

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953366521 1662 AQLAgmgsgALREV--TYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEEL 1722
Cdd:PRK03918   477 KLRK-----ELRELekVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKL 534
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1214-1542 1.46e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 1.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1214 DSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQE 1293
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR 792

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1294 TAEhgLAEELEGLRQQLQQAAQQQAELKEENSALwsqkeasaaeaeareaalrrevECLTQEQSEARKQSEKDRAALLSQ 1373
Cdd:TIGR02169  793 IPE--IQAELSKLEEEVSRIEARLREIEQKLNRL----------------------TLEKEYLEKEIQELQEQRIDLKEQ 848

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1374 MKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAArprph 1453
Cdd:TIGR02169  849 IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK----- 923

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1454 gprVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMiqEEEIRRLEETNAScrreAAQLREELERQRDAMKA- 1532
Cdd:TIGR02169  924 ---AKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRV--EEEIRALEPVNML----AIQEYEEVLKRLDELKEk 994

                          330
                   ....*....|...
gi 1953366521 1533 ---LQQDKEALQE 1542
Cdd:TIGR02169  995 rakLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1267-1543 1.64e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1267 ELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALwSQKEASAAEAEAREAALR 1346
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL-EAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1347 REVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEAcakQAEELSALRQQMAALDKHLRSQRQfmDEQAVER 1426
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA---LREALDELRAELTLLNEEAANLRE--RLESLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1427 EHEREEfqREIQRLEEQLRQAArprphgprvSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVM-------IQE 1499
Cdd:TIGR02168  832 RIAATE--RRLEDLEEQIEELS---------EDIESLAAEIEELEELIEELESELEALLNERASLEEALAllrseleELS 900

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1953366521 1500 EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEK 1543
Cdd:TIGR02168  901 EELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 580-1063 1.75e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  580 LKEDLERVKHSLVEDhREELKKANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLmlhdlkEQAEAEKQSVINKFEL 659
Cdd:COG1196    314 LEERLEELEEELAEL-EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA------EAELAEAEEELEELAE 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  660 REIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcGQEPAGRVAPADQDWELATRRLREDCALQLMQ 739
Cdd:COG1196    387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE-------EALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  740 AQSRFLKERKELTEKFTAEQDALLQEAQEKHAcdmrllqerhqqhVLSLTAQLEARRRAEVEELKASVESERWALAEARV 819
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAA-------------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  820 AELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQlRVDLEKQLQEKEASHPTPLTQALEKHPLSHGQE 899
Cdd:COG1196    527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG-RATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  900 LPPVEGGLRTQTSSGQLEGVKAPVPP----------------EVQGAQQEGAPVPAEVEAQRPALLAELRQETGKQQLHC 963
Cdd:COG1196    606 SDLREADARYYVLGDTLLGRTLVAARleaalrravtlagrlrEVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  964 QEEPEVLEcpsepFLEQQILQpkgefESEKKVALHEKEIHGLECAQAQSLYQKEKESLFLQLQEKNNQILQLKEQILSLS 1043
Cdd:COG1196    686 ERLAEEEL-----ELEEALLA-----EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                          490       500
                   ....*....|....*....|
gi 1953366521 1044 HEVEERRRDLEQLQQRRERE 1063
Cdd:COG1196    756 LPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1392-1723 1.90e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.90e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1392 AKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREH--EREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLD---EE 1466
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKaeRYQALLKEKREYEGYELLKEKEALERQKEAIERQLAsleEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1467 VELLQEKLREKSDGFNELVIKKELADRQVM-IQEEEIRRLeetnascRREAAQLREELERQRDAMKALQQDKEALQEKQM 1545
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEELNKKIKdLGEEEQLRV-------KEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1546 SNLLLVSTLQSKLdegrcpvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLgkmkDDLVSKSDEVLHLNLELDAQS 1625
Cdd:TIGR02169  326 KLEAEIDKLLAEI--------------EELEREIEEERKRRDKLTEEYAELKEEL----EDLRAELEEVDKEFAETRDEL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1626 SRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQ---LEAQLAGMgSGALREVTYDRSSEIEELRSIIENLRENQQRLQK 1702
Cdd:TIGR02169  388 KDYREKLEKLKREINELKRELDRLQEELQRLSEEladLNAAIAGI-EAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340
                   ....*....|....*....|.
gi 1953366521 1703 EKaEEMEQLHEVIERLQEELS 1723
Cdd:TIGR02169  467 YE-QELYDLKEEYDRVEKELS 486
PTZ00121 PTZ00121
MAEBL; Provisional
 2524-2907 1.96e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2524 QLRRQVELLAYkvEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRdlRSELRECKQDNERLLASLGEAQKEVLQLR 2603
Cdd:PTZ00121  1083 AKEDNRADEAT--EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARK--AEEARKAEDARKAEEARKAEDAKRVEIAR 1158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2604 SVLDSKESNLRAALQELESERGKERALQSR-LEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDN 2682
Cdd:PTZ00121  1159 KAEDARKAEEARKAEDAKKAEAARKAEEVRkAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKD 1238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2683 LQKELQIEASRC-EALLAQERGQLSELQRSLEAEKGRSLELAAALR--HERLLTEQLSRGPRESPAHHAllRKLKEEKSR 2759
Cdd:PTZ00121  1239 AEEAKKAEEERNnEEIRKFEEARMAHFARRQAAIKAEEARKADELKkaEEKKKADEAKKAEEKKKADEA--KKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2760 AAELQARLEQVQRQqeADVQKRRAElEREKEVRAAQAREPGRCLRREGHASQQQAG-LEPLQAGLAAQEGRKDA---RRA 2835
Cdd:PTZ00121  1317 ADEAKKKAEEAKKK--ADAAKKKAE-EAKKAAEAAKAEAEAAADEAEAAEEKAEAAeKKKEEAKKKADAAKKKAeekKKA 1393

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366521 2836 DVGPGRADAEMRPTgakEKLRELELQRQRDEHKIRQLQRTVQALEAK---EEAAQRPEAERLQEERLGLERVRQQ 2907
Cdd:PTZ00121  1394 DEAKKKAEEDKKKA---DELKKAAAAKKKADEAKKKAEEKKKADEAKkkaEEAKKADEAKKKAEEAKKAEEAKKK 1465
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 251-872 2.27e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 2.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  251 LENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERcqyvqdlELR 330
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY-------ELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  331 LRDQEVEKQLELESLRASYAELKAQSQEEIRRLWSQlesprpDRQDASARTPhgEELEQRERECGVQQQRRGRRAEQESE 410
Cdd:COG1196    295 AELARLEQDIARLEERRRELEERLEELEEELAELEE------ELEELEEELE--ELEEELEEAEEELEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  411 LGQSPEGAAERGREDPVLLEQRLQDATEEPSLEsggigpSSMREGERREQRvgpslqpelAENHRCHLTAWTSSLEAQQQ 490
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELA------AQLEELEEAEEA---------LLERLERLEEELEELEEALA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  491 AGLVETQESEGEQREglsegpgqeltqvpvpcAQGTALKVDTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRNL 570
Cdd:COG1196    432 ELEEEEEEEEEALEE-----------------AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  571 heklqhevcLKEDLERVKHSLVEDHREELKKANERL--QLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEA 648
Cdd:COG1196    495 ---------LLLEAEADYEGFLEGVKAALLLAGLRGlaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  649 EKQSVINKFE-LREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEEcprcghcGQEPAGRVAPADQDWELATR 727
Cdd:COG1196    566 LKAAKAGRATfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL-------GDTLLGRTLVAARLEAALRR 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  728 RLREDCALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKhacdMRLLQERHQQHVLSLTAQLEARRRAEVEELKASV 807
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE----LEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366521  808 ESERWALAEARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAmREEHRQALEQLRVDLEK 872
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLEREIEA 778
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1236-1720 2.67e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.59  E-value: 2.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1236 KNEETAQVVRKQQQLLERLEEENA-ARTRLMLELHQAQGI---IEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQ 1311
Cdd:PRK02224   273 EREELAEEVRDLRERLEELEEERDdLLAEAGLDDADAEAVearREELEDRDEELRDRLEECRVAAQAHNEEAESLREDAD 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1312 QAAQQQAELKEENSALWSQkeasaaeaearEAALRREVECLTQEQSEARKQSEKDRAALLSQmkvfEAELEEQLSRHEAC 1391
Cdd:PRK02224   353 DLEERAEELREEAAELESE-----------LEEAREAVEDRREEIEELEEEIEELRERFGDA----PVDLGNAEDFLEEL 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1392 akqAEELSALRQQMAALDKHLRSQRQFMDE--------------QAVERE---HEREEFQREIQRLEEQLRQAArprphg 1454
Cdd:PRK02224   418 ---REERDELREREAELEATLRTARERVEEaealleagkcpecgQPVEGSphvETIEEDRERVEELEAELEDLE------ 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1455 prvSDEEQLDEEVELLqEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQ 1534
Cdd:PRK02224   489 ---EEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAE 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1535 QDKEALQEKqmsnlllVSTLQSKLDEGRCPVPPADSCPEGPEvQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEV 1614
Cdd:PRK02224   565 EEAEEAREE-------VAELNSKLAELKERIESLERIRTLLA-AIADAEDEIERLREKREALAELNDERRERLAEKRERK 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1615 LHLNLELDAQssraavSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSgalrevtydRSSEIEELrsiiENLR 1694
Cdd:PRK02224   637 RELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGA---------VENELEEL----EELR 697

                          490       500
                   ....*....|....*....|....*.
gi 1953366521 1695 ENQQRLQkEKAEEMEQLHEVIERLQE 1720
Cdd:PRK02224   698 ERREALE-NRVEALEALYDEAEELES 722
PTZ00121 PTZ00121
MAEBL; Provisional
 1214-1537 2.91e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1214 DSTRQLEEARQIHSRFEKEFSCKNEET--AQVVRKQQQLlERLEEENAARTRLMLELHQAQgiiEGFKEEKASLQEALCR 1291
Cdd:PTZ00121  1525 DEAKKAEEAKKADEAKKAEEKKKADELkkAEELKKAEEK-KKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKL 1600

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1292 QETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAALRREVECLTQEQSEARKQSEKDRAALL 1371
Cdd:PTZ00121  1601 YEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1372 SQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQ--RLEEQLRQAAR 1449
Cdd:PTZ00121  1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEeaKKDEEEKKKIA 1760

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1450 PRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIK--KELADRQVMIQEEEIRRLEETNASCRREAAQLREELER-- 1525
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKkiKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSkn 1840

                          330
                   ....*....|...
gi 1953366521 1526 -QRDAMKALQQDK 1537
Cdd:PTZ00121  1841 mQLEEADAFEKHK 1853
PTZ00121 PTZ00121
MAEBL; Provisional
 245-1080 6.69e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 6.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  245 SERGLCLENLRRELSAKHRS-ELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQLREDLQSERCQY 323
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNrADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  324 VQDLELRLRDQEVEKQLELESLR----ASYAElKAQSQEEIRRlwsqlesprpdrqdasartphGEELEQRERecgVQQQ 399
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARkaedAKKAE-AARKAEEVRK---------------------AEELRKAED---ARKA 1202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  400 RRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRVGPSLQPELAENHRchlt 479
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR---- 1278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  480 AWTSSLEAQQQAGLVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDTEVVARglGLEAEHRLKLLLLQTELKEE 559
Cdd:PTZ00121  1279 KADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKK--KAEEAKKAAEAAKAEAEAAA 1356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  560 MDVLKLENRNLHEKLQHEVCLKEDLERVKHSLVEDHREELKKANERLQLVKQELKDKEAEWKVAsEDLKRKAEEELTlmL 639
Cdd:PTZ00121  1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKK--A 1433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  640 HDLKEQAEAEKQSVINKFELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEECPRcghcGQEPAGRVAPAD 719
Cdd:PTZ00121  1434 DEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKK----KADEAKKAAEAK 1509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  720 QDWELATRRLREDCALQLMQA-QSRFLKERKELTEKFTAEQ---DALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEAR 795
Cdd:PTZ00121  1510 KKADEAKKAEEAKKADEAKKAeEAKKADEAKKAEEKKKADElkkAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA 1589

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  796 RRAEVEELKASVESERWALAEarvaELQTEHAAAISALEARHSallgSLESRHLSEVQAMREEHRQALEQLRVDLEKQL- 874
Cdd:PTZ00121  1590 EEARIEEVMKLYEEEKKMKAE----EAKKAEEAKIKAEELKKA----EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKi 1661

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  875 -QEKEASHPTPLTQALEKHPLSHGQELPPVEGGLRTQTSSGQLEGVKAPVPPEVQGAQQ-----EGAPVPAEvEAQRPA- 947
Cdd:PTZ00121  1662 kAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEElkkaeEENKIKAE-EAKKEAe 1740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  948 ----LLAELRQETGK----QQLHCQEEPEVLECPSEpflEQQILQPKGEFESEKKVALHEKEIHGLECAQAQSLYQKEKE 1019
Cdd:PTZ00121  1741 edkkKAEEAKKDEEEkkkiAHLKKEEEKKAEEIRKE---KEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEG 1817

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953366521 1020 SLFLQlQEKNNQILQLKEQILSlSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSDADL 1080
Cdd:PTZ00121  1818 NLVIN-DSKEMEDSAIKEVADS-KNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDL 1876
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1238-1542 8.31e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 8.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1238 EETAQVVRKQQQLLERLEEENAARTR---LMLELHQAQGII-----EGFKEEKASLQEALCRQETAEHGLAEELEGLRQQ 1309
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERyqaLLKEKREYEGYEllkekEALERQKEAIERQLASLEEELEKLTEEISELEKR 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1310 LQQAAQQQAELKEENSALWS------QKEASAAEAEAREAALRREVECLTQEQSEAR-KQSEKDRAALLSQMKVFEAELE 1382
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKDLGEeeqlrvKEKIGELEAEIASLERSIAEKERELEDAEERlAKLEAEIDKLLAEIEELEREIE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1383 EQLSRHEAC----AKQAEELSALRQQMAALDKHLRSQRQFMDEQAVERE---HEREEFQREIQRLEEQLRQA----ARPR 1451
Cdd:TIGR02169  347 EERKRRDKLteeyAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEklkREINELKRELDRLQEELQRLseelADLN 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1452 PHGPRVSDE-EQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAqlreELERQRDAM 1530
Cdd:TIGR02169  427 AAIAGIEAKiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELA----EAEAQARAS 502

                          330
                   ....*....|..
gi 1953366521 1531 KALQQDKEALQE 1542
Cdd:TIGR02169  503 EERVRGGRAVEE 514
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1354-1721 2.64e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 2.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1354 QEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELS----ALRQQMAALDKHLRSQRQFMDEQAVEREHE 1429
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEkeieQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1430 REEFQREIQRLEEQLRQAARPRphgprvsdEEQLDEEVELLQEKLREKSDGFNELvikkeladrqvmiqEEEIRRLEETN 1509
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLE--------EALNDLEARLSHSRIPEIQAELSKL--------------EEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1510 ASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEgrcpvppadscpegPEVQLEAVQRALQQR 1589
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE--------------LEEELEELEAALRDL 880

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1590 ESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAA---VSVRELQEENASLKAFLQNKEKEIMCVS--EQLEAQL 1664
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSelkAKLEALEEELSEIEDPKGEDEEIPEEELslEDVQAEL 960

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521 1665 AGMGSG--ALREVTYDRSSEIEELRSIIENLRENQQRLQKEKaeemEQLHEVIERLQEE 1721
Cdd:TIGR02169  961 QRVEEEirALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEER----KAILERIEEYEKK 1015
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2452-2906 2.91e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 2.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2452 EHSSLLERLEKVVQEQEKsLEHLRASDRSSLL-SEIQALRAQLRmthlQNQEKLQQLCAALTSAEARGSRQEHQLR---- 2526
Cdd:COG4913    263 RYAAARERLAELEYLRAA-LRLWFAQRRLELLeAELEELRAELA----RLEAELERLEARLDALREELDELEAQIRgngg 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2527 RQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELREckqdnerLLASLGEAQKEVLQLRSVL 2606
Cdd:COG4913    338 DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA-------LLEALEEELEALEEALAEA 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2607 DSKESNLRAALQELESERGKERALQSRLEEAQLQHLQR-EGQSSKTLEEL----------------RASLEK---QFAQS 2666
Cdd:COG4913    411 EAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAlAEALGLDEAELpfvgelievrpeeerwRGAIERvlgGFALT 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2667 sqLCVALKHEQTAK---DNLQKELQIEASRCEALLAQERGQ--------------LSELQRSLEAEKGRSLELA-----A 2724
Cdd:COG4913    491 --LLVPPEHYAAALrwvNRLHLRGRLVYERVRTGLPDPERPrldpdslagkldfkPHPFRAWLEAELGRRFDYVcvdspE 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2725 AL-RHERLLTEQ-LSRGPRESPAH--------------------HALLRKLKEEKSRAAELQARLEQVQRQQEAdVQKRR 2782
Cdd:COG4913    569 ELrRHPRAITRAgQVKGNGTRHEKddrrrirsryvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDA-LQERR 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2783 AELEREKEVRAAQAREPGrcLRREGHASQQQ-AGLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELELQ 2861
Cdd:COG4913    648 EALQRLAEYSWDEIDVAS--AEREIAELEAElERLDASSDDLAALEEQLEELEAE----LEELEEELDELKGEIGRLEKE 721

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1953366521 2862 RQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERLGLERVRQ 2906
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERE 766
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1356-1542 3.00e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1356 QSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEEL----SALRQQMAALDKHLRSQRQFMDEQAVEREHERE 1431
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALerriAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1432 EFQREIQRLEEQLRQAARPRPHGP---RVSDE----------------EQLDEEVELLQEKLREKSDGFNELVIKKELAD 1492
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPlalLLSPEdfldavrrlqylkylaPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1493 RQVMIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQE 1542
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 950-1596 3.86e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 3.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  950 AELRQETGKQQLHCQEEPEVLecpsepfLEQQILQPKGEFESEKKvALHEKEihglecAQAQSLYQKEKEsLFLQLQEKN 1029
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAE-------LEEKLEELKEELESLEA-ELEELE------AELEELESRLEE-LEEQLETLR 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1030 NQILQLKEQILSLSHEVEERRRDLEQLQQRRERENQEGTNLismLKSDADLSDRERRALRDALRRLLSLFGEMLKVAIAL 1109
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEL---LKKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1110 KSRISERVGLCLEDEDPPG-------------------------------AWPSGQALSAAPVLE--ETWPGSEAALLEL 1156
Cdd:TIGR02168  463 LEELREELEEAEQALDAAErelaqlqarldslerlqenlegfsegvkallKNQSGLSGILGVLSEliSVDEGYEAAIEAA 542

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1157 DRSLPECVEMPSEAEISSHICesfFMSPESS-----LEYEQPIRRIYQSLGLAVEGLLELALDSTRQLEEARqihSRFEK 1231
Cdd:TIGR02168  543 LGGRLQAVVVENLNAAKKAIA---FLKQNELgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD---PKLRK 616

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1232 EFS--------CKNEETAQVVRKQQQLLERL------------------EEENAARTRLMLELHQAQGIIEGFKEEKASL 1285
Cdd:TIGR02168  617 ALSyllggvlvVDDLDNALELAKKLRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAEL 696

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1286 QEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALwSQKEASAAEAEAREAALRREVECLTQEQSEARKQSEK 1365
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL-EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1366 DRAALLSQMKVFEAELEEQLSRHEAcakQAEELSALRQQMAALDKHLRSQRQfmDEQAVEREHEREEfqREIQRLEEQLR 1445
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKA---LREALDELRAELTLLNEEAANLRE--RLESLERRIAATE--RRLEDLEEQIE 848

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1446 QAArprphgprvSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELER 1525
Cdd:TIGR02168  849 ELS---------EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953366521 1526 QRDAMKALQQDKEALQekqmsnlLLVSTLQSKL-DEGRCPVPPADSCPEGPEVQLEAVQRALQQRESEVLDL 1596
Cdd:TIGR02168  920 LREKLAQLELRLEGLE-------VRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2572-2893 1.03e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2572 RDLRSELRECKQdnERLLASLGEAQKEVLQLRSVLDSKESNLrAALQELESERGKE-RALQSRLEEAQLQHLQREGQSSK 2650
Cdd:TIGR02169  214 QALLKEKREYEG--YELLKEKEALERQKEAIERQLASLEEEL-EKLTEEISELEKRlEEIEQLLEELNKKIKDLGEEEQL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2651 TLEELRASLEKQFAQssqlcvaLKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHER 2730
Cdd:TIGR02169  291 RVKEKIGELEAEIAS-------LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2731 LLTEQL-SRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQARepgrclrREGHA 2809
Cdd:TIGR02169  364 EELEDLrAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAG-------IEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2810 SQQQAGLEPLQAGLAAQEGRKDARRADVGPgradaemrptgAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRP 2889
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSK-----------YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505


                   ....
gi 1953366521 2890 EAER 2893
Cdd:TIGR02169  506 VRGG 509
PTZ00121 PTZ00121
MAEBL; Provisional
 1353-2068 1.10e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.68  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1353 TQEQSEARKQSEKDRaallsqmKVFEAELEEQLSRHEAcAKQAEELSALRQQMAALD-KHLRSQRQFMDEQAVEREHERE 1431
Cdd:PTZ00121  1090 DEATEEAFGKAEEAK-------KTETGKAEEARKAEEA-KKKAEDARKAEEARKAEDaRKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1432 EFQR--EIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQvmiqeEEIRRLEETN 1509
Cdd:PTZ00121  1162 DARKaeEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKA-----EAVKKAEEAK 1236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1510 ascRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLllvstlqsKLDEGRcpvpPADSCPEGPEV-QLEAVQRALQQ 1588
Cdd:PTZ00121  1237 ---KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAI--------KAEEAR----KADELKKAEEKkKADEAKKAEEK 1301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1589 RESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELD--AQSSRAAVSVRELQEENASLKAFLQNKEKEimcvSEQLEAQLAG 1666
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAE----AAEKKKEEAK 1377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1667 MGSGALREVTyDRSSEIEELRSIIENLRENQQRLQKEKAEE--MEQLHEVIERLQEELSLGAPAVPAAVDCELPAVPAPA 1744
Cdd:PTZ00121  1378 KKADAAKKKA-EEKKKADEAKKKAEEDKKKADELKKAAAAKkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEA 1456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1745 VGPEALAAAGAASRLFAE-----QEHRHGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAALRA 1819
Cdd:PTZ00121  1457 KKAEEAKKKAEEAKKADEakkkaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA 1536

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1820 KEARLAERDLEIDAMKRQKLAHSAELetilaafsrfRRTLERQPLAAEDEPPELQRLRVQcvrlsrqlqvlnqrflrcqk 1899
Cdd:PTZ00121  1537 DEAKKAEEKKKADELKKAEELKKAEE----------KKKAEEAKKAEEDKNMALRKAEEA-------------------- 1586

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1900 eadkQQARGARLRPRGARGLQGPGPRAEEASRDEASQQDVDSRQVASATQGQVRDPQNAVNDDLQPAElpvtsgppGLLK 1979
Cdd:PTZ00121  1587 ----KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE--------ELKK 1654

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1980 QDSVMSVLAVCQRQLESELLLLKNEMHLRTEDRGKAPARMKNKENllEDRQLQKVGliSQVKELQEKLNHLVRSVNFQNI 2059
Cdd:PTZ00121  1655 AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE--EAKKAEELK--KKEAEEKKKAEELKKAEEENKI 1730


                   ....*....
gi 1953366521 2060 ETEDFKSQQ 2068
Cdd:PTZ00121  1731 KAEEAKKEA 1739
mukB PRK04863
chromosome partition protein MukB;
2458-2900 1.38e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.11  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2458 ERLEKVVQEQEKSlehlrASDRSSLLSEIQALRA--QLRMTHLQNQEKLQQLCAALTSAEARgsrqehqLRRQVELLAyk 2535
Cdd:PRK04863   307 YRLVEMARELAEL-----NEAESDLEQDYQAASDhlNLVQTALRQQEKIERYQADLEELEER-------LEEQNEVVE-- 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2536 VEQEKRIASDVQKTLTEEQekassvrkllvveqtvVRDLRSELRECKQdnerllaSLGEAQKEVLQLR---SVLDSKESN 2612
Cdd:PRK04863   373 EADEQQEENEARAEAAEEE----------------VDELKSQLADYQQ-------ALDVQQTRAIQYQqavQALERAKQL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2613 LRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRaslekQFAQSSQLCVALKHE-------QTAKDNLQK 2685
Cdd:PRK04863   430 CGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHS-----QFEQAYQLVRKIAGEvsrseawDVARELLRR 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2686 --ELQIEASRCEALlaqeRGQLSELQRSLEAEKgrslelaaalRHERLLTE---QLSRGP-------RESPAHHALLRKL 2753
Cdd:PRK04863   505 lrEQRHLAEQLQQL----RMRLSELEQRLRQQQ----------RAERLLAEfckRLGKNLddedeleQLQEELEARLESL 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2754 KEEKSRAAELQARLEQVQRQQEADVQKRRAeleREKEVRAAQARepgrclrreghasqqqagLEPLQAglaaQEGRKDAR 2833
Cdd:PRK04863   571 SESVSEARERRMALRQQLEQLQARIQRLAA---RAPAWLAAQDA------------------LARLRE----QSGEEFED 625

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521 2834 RADVgpgraDAEMRPTgaKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAaqrpEAERLQE--ERLG 2900
Cdd:PRK04863   626 SQDV-----TEYMQQL--LERERELTVERDELAARKQALDEEIERLSQPGGS----EDPRLNAlaERFG 683
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2457-2668 2.22e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2457 LERLEKVVQEQEKSLEHLRAsDRSSLLSEIQALRAQLRMTHLQ---NQEKLQQLCAALTSAEARGSRQEHQLRRQVELLA 2533
Cdd:COG4942     29 LEQLQQEIAELEKELAALKK-EEKALLKQLAALERRIAALARRiraLEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2534 YKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDskesNL 2613
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA----EL 183

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1953366521 2614 RAALQELESERGKERALQSRLE---EAQLQHLQREGQSSKTLEELRASLEKQFAQSSQ 2668
Cdd:COG4942    184 EEERAALEALKAERQKLLARLEkelAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1214-1708 2.41e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.11  E-value: 2.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1214 DSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLML-------ELHQAQGIIEGFKEEKASLQ 1286
Cdd:pfam05483  258 DLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMStqkaleeDLQIATKTICQLTEEKEAQM 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1287 EALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENsalwsqkeasaaeaeareaalRREVECLTQEQSEARKQSEK- 1365
Cdd:pfam05483  338 EELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKN---------------------EDQLKIITMELQKKSSELEEm 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1366 -----DRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRL 1440
Cdd:pfam05483  397 tkfknNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDL 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1441 EEQLRQAARPRPHGPRVSDEEQLDEevellQEKLREKSDGFNELviKKELADRQVMIQEEE-----IRRLEETNASCRRE 1515
Cdd:pfam05483  477 KTELEKEKLKNIELTAHCDKLLLEN-----KELTQEASDMTLEL--KKHQEDIINCKKQEErmlkqIENLEEKEMNLRDE 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1516 AAQLREELERQRDAMKAlQQDKEALQEKQMSNLLLVSTLQSKLDEGRCpvppadscpEGPEVQLEAVQRALQQRESEVLD 1595
Cdd:pfam05483  550 LESVREEFIQKGDEVKC-KLDKSEENARSIEYEVLKKEKQMKILENKC---------NNLKKQIENKNKNIEELHQENKA 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1596 LKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSV----RELQEENASLKAFLQNKEKEIMCVSEQLEAQlagmgsga 1671
Cdd:pfam05483  620 LKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIdnyqKEIEDKKISEEKLLEEVEKAKAIADEAVKLQ-------- 691

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1953366521 1672 lREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEM 1708
Cdd:pfam05483  692 -KEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSEL 727
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 137-875 4.20e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 4.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  137 SLELEALRLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQeLALLRSRQQQELELAREQHAREQEEMRLRCSQ 216
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ-WKEKRDELNGELSAADAAVAKDRSELEALEDQ 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  217 ETAKLKEKLQSEMERNARAvESLKRDWE--SERGLCLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQA 294
Cdd:pfam12128  331 HGAFLDADIETAAADQEQL-PSWQSELEnlEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  295 ECALRTLEAQHEEALRQLREDLQSErcqyVQDLELRLRDQEVEKQLELESLRASYAEL--KAQSQEEIRRLWSQLESPRP 372
Cdd:pfam12128  410 LAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPELLlqLENFDERIERAREEQEAANA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  373 DRQDAsartphgeeleQRERecgvqQQRRGRRAEQESELGQSPEGAAERgredpvllEQRLQDATEEPSLESGGIGPSSM 452
Cdd:pfam12128  486 EVERL-----------QSEL-----RQARKRRDQASEALRQASRRLEER--------QSALDELELQLFPQAGTLLHFLR 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  453 REGERREQRVGPSLQPELAenHRCHLTAwtssleaqqqaglVETQESEGEQREGLSEGPGQELTQVPVPCAQGTALKVDT 532
Cdd:pfam12128  542 KEAPDWEQSIGKVISPELL--HRTDLDP-------------EVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  533 EVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLEnrnlheklqhevclkedLERVKHSLvEDHREELKKANERLQLVKQE 612
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASRE-----------------ETFARTAL-KNARLDLRRLFDEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  613 LKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQsvinkfELREIKMRQLQDQQAaqildLEGSLVEQQGRLRQL 692
Cdd:pfam12128  669 KNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKE------QKREARTEKQAYWQV-----VEGALDAQLALLKAA 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  693 EHGLEAEECPRCGHCGQEPAGRVAPADQDWELATRRLREdcALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKHAc 772
Cdd:pfam12128  738 IAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKRE--IRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLAT- 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  773 dmrlLQERHQQHVLSLTAQLeARRRAEVEELKASVESERWAL--AEARVAELQTEHAAAISALEARHSALLGSLESRHLS 850
Cdd:pfam12128  815 ----QLSNIERAISELQQQL-ARLIADTKLRRAKLEMERKASekQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIG 889

                          730       740
                   ....*....|....*....|....*
gi 1953366521  851 EVQAMREEHRQALEQLRVDLEKQLQ 875
Cdd:pfam12128  890 ERLAQLEDLKLKRDYLSESVKKYVE 914
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1355-1553 4.87e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.35  E-value: 4.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1355 EQSEARKQSEKDRAALLSQMKVFEAELEE-QLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEF 1433
Cdd:pfam17380  354 RQEERKRELERIRQEEIAMEISRMRELERlQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1434 QREIQRLEEQ-------LRQAARPRPHGP---RVSDEEQLDEEVELLQEKL-REKSDGFNELVIKKEL-ADRQVMIQEEE 1501
Cdd:pfam17380  434 QREVRRLEEEraremerVRLEEQERQQQVerlRQQEEERKRKKLELEKEKRdRKRAEEQRRKILEKELeERKQAMIEEER 513

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1953366521 1502 IRRLEETNASCRREAAQlreELERQRDAMKALQQDKEALQEKQMSNLLLVST 1553
Cdd:pfam17380  514 KRKLLEKEMEERQKAIY---EEERRREAEEERRKQQEMEERRRIQEQMRKAT 562
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2502-2785 5.03e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 49.28  E-value: 5.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2502 EKLQQLCAALTS-AEARGSRQEHQLRRQVellaykVEQEKRIASDVQKTLTEEQEKASSVRKLLVV---EQTVVrdlrse 2577
Cdd:PRK10929    45 EIVEALQSALNWlEERKGSLERAKQYQQV------IDNFPKLSAELRQQLNNERDEPRSVPPNMSTdalEQEIL------ 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2578 lreckQDNERLLASLGEAQKEVLQLRSVLDS------KESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSK- 2650
Cdd:PRK10929   113 -----QVSSQLLEKSRQAQQEQDRAREISDSlsqlpqQQTEARRQLNEIERRLQTLGTPNTPLAQAQLTALQAESAALKa 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2651 TLEELraslekQFAQSSqlcvALKHEQTAKdnLQKEL-QIEASRCEALLAQERGQLSElQRSLEAEKgrslelaaALRHE 2729
Cdd:PRK10929   188 LVDEL------ELAQLS----ANNRQELAR--LRSELaKKRSQQLDAYLQALRNQLNS-QRQREAER--------ALEST 246

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953366521 2730 RLLTEQLSRGPRespahhALLRKLK--EEKSRAAELQA-RLEQV---QRQQEADVQKRRAEL 2785
Cdd:PRK10929   247 ELLAEQSGDLPK------SIVAQFKinRELSQALNQQAqRMDLIasqQRQAASQTLQVRQAL 302
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 88-382 5.63e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 5.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521   88 QDREQDCKLEIAQPMGRQEDEAGAQQQVAVELRQPAGMQQVQLQTQPVPSLELEALRLSLSNMHTAQLELTQANLQKEKE 167
Cdd:pfam17380  298 QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRM 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  168 TALTELRamlngrhaQELALLRSRQQQELELAREQHAREQEEMR-----------LRCSQETAKLKEKLQSEMERnARAV 236
Cdd:pfam17380  378 RELERLQ--------MERQQKNERVRQELEAARKVKILEEERQRkiqqqkvemeqIRAEQEEARQREVRRLEEER-AREM 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  237 ESLKRDwESERGLCLENLRRELSAKHRSELENLQDQFKRELSEQ------KAELEKIFQAKNQAECALRTLEAQHEEALR 310
Cdd:pfam17380  449 ERVRLE-EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEqrrkilEKELEERKQAMIEEERKRKLLEKEMEERQK 527

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366521  311 QLREDLQSERCQyvqdlELRLRDQEVE--KQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDASARTP 382
Cdd:pfam17380  528 AIYEEERRREAE-----EERRKQQEMEerRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEATTP 596
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2460-2899 5.75e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 5.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2460 LEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRM------THLQNQEKLQQLCAALTSAEARGSRQEHQLRR-QVELL 2532
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEaeekeeEYAELQEELEELEEELEELEAELEELREELEKlEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2533 AYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEvlQLRSVLDSKESn 2612
Cdd:COG4717    127 LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEE--ELQDLAEELEE- 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2613 LRAALQELESERGKERALQSRLEEaQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKE---LQI 2689
Cdd:COG4717    204 LQQRLAELEEELEEAQEELEELEE-ELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2690 EASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQ---LSRGPRESPAHHALLRKLKEEKSRAAELQAR 2766
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALglpPDLSPEELLELLDRIEELQELLREAEELEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2767 LEQVQRQQEADVQKRRAELEREKEVRAAqarepgrcLRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEM 2846
Cdd:COG4717    363 LQLEELEQEIAALLAEAGVEDEEELRAA--------LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEEL 434

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953366521 2847 RptGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERL 2899
Cdd:COG4717    435 E--ELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAEL 485
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1352-1722 6.17e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 6.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1352 LTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEE--------LSALRQQMAALDKhLRSQRQFMDEQA 1423
Cdd:PRK02224   189 LDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQAREtrdeadevLEEHEERREELET-LEAEIEDLRETI 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1424 VEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLDEE-VELLQEKLREKSDGfnelvIKKELADRQVMIQE--- 1499
Cdd:PRK02224   268 AETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEaVEARREELEDRDEE-----LRDRLEECRVAAQAhne 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1500 ------EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKqmsnlllvstlqskLDEGRCPVppadscpE 1573
Cdd:PRK02224   343 eaeslrEDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEE--------------IEELRERF-------G 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1574 GPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDA----------QSSRAAVSVRELQEENASLK 1643
Cdd:PRK02224   402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1644 AFLQNKEKEIMCVSEQLEA--QLAGMGSG---------ALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1712
Cdd:PRK02224   482 AELEDLEEEVEEVEERLERaeDLVEAEDRierleerreDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAA 561

                          410
                   ....*....|
gi 1953366521 1713 EVIERLQEEL 1722
Cdd:PRK02224   562 EAEEEAEEAR 571
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1245-1535 8.38e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.58  E-value: 8.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1245 RKQQQLLERLEEEN--AARTRLMLELHQAQGIIEGFKEEKASL-QEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELK 1321
Cdd:pfam17380  287 RQQQEKFEKMEQERlrQEKEEKAREVERRRKLEEAEKARQAEMdRQAAIYAEQERMAMERERELERIRQEERKRELERIR 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1322 EENSALWSQKEASAAEAEAREAALRREVEcltQEQSEARKQS--EKDRaallsQMKVFEAELEEQLSRHEACAKQAEELS 1399
Cdd:pfam17380  367 QEEIAMEISRMRELERLQMERQQKNERVR---QELEAARKVKilEEER-----QRKIQQQKVEMEQIRAEQEEARQREVR 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1400 ALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKsd 1479
Cdd:pfam17380  439 RLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRK-- 516

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366521 1480 gfnelVIKKELADRQVMIQEEEIRRLEETNascRREAAQLREELERQRDAMKALQQ 1535
Cdd:pfam17380  517 -----LLEKEMEERQKAIYEEERRREAEEE---RRKQQEMEERRRIQEQMRKATEE 564
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1217-1549 1.12e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.84  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1217 RQLEEARQIHSRFEKEFSCKNEETAQVVRKQ-QQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETA 1295
Cdd:COG4717    163 EELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1296 EHGLAEE----LEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAALRREVECLTQEQSEARKQSEKDRAALL 1371
Cdd:COG4717    243 ERLKEARllllIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1372 SQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMD----------------EQAVEREHEREEFQR 1435
Cdd:COG4717    323 ELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEiaallaeagvedeeelRAALEQAEEYQELKE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1436 EIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELviKKELADRQVMIQE-EEIRRLEETNASCRR 1514
Cdd:COG4717    403 ELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEEL--REELAELEAELEQlEEDGELAELLQELEE 480

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 1953366521 1515 EAAQLREELER---QRDAMKALQQDKEALQEKQMSNLL 1549
Cdd:COG4717    481 LKAELRELAEEwaaLKLALELLEEAREEYREERLPPVL 518
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1220-1893 1.29e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.14  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1220 EEARQIHSRFEKEFSckneETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGL 1299
Cdd:TIGR02169  287 EEQLRVKEKIGELEA----EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1300 AEELEGLRQQLQQAAQQQAELKEENSALwSQKEASAAEAEAREAALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEA 1379
Cdd:TIGR02169  363 KEELEDLRAELEEVDKEFAETRDELKDY-REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1380 ELEEqlsRHEACAKQAEELSALRQQMAALDKHLRSQRQfmDEQAVEREheREEFQREIQRLEEQlRQAARPRPHGpRVSD 1459
Cdd:TIGR02169  442 EKED---KALEIKKQEWKLEQLAADLSKYEQELYDLKE--EYDRVEKE--LSKLQRELAEAEAQ-ARASEERVRG-GRAV 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1460 EEQLDEEVELLQEKLRE-------------------------KSDGFNELVI---KKELADRQVMIQEEEIRRLEETNAS 1511
Cdd:TIGR02169  513 EEVLKASIQGVHGTVAQlgsvgeryataievaagnrlnnvvvEDDAVAKEAIellKRRKAGRATFLPLNKMRDERRDLSI 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1512 CRRE-----AAQLREELERQRDAMKALQQDKEALQE-----KQMSNLLLVsTLQSKLDEgrcpvpPADSCPEGPEVQLEA 1581
Cdd:TIGR02169  593 LSEDgvigfAVDLVEFDPKYEPAFKYVFGDTLVVEDieaarRLMGKYRMV-TLEGELFE------KSGAMTGGSRAPRGG 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1582 VQRALQQREsEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEenaslkaflqnKEKEImcvsEQLE 1661
Cdd:TIGR02169  666 ILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE-----------IEKEI----EQLE 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1662 AQLAgmgsgALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEvierLQEELSlgapavpaavdcELPAVP 1741
Cdd:TIGR02169  730 QEEE-----KLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK----LEEALN------------DLEARL 788

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1742 APAVGPEALAAAGAASRLFAEQEHRhGQALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAALRAKE 1821
Cdd:TIGR02169  789 SHSRIPEIQAELSKLEEEVSRIEAR-LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE 867

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366521 1822 ARLAERDLEIdamkrqklahsAELETILAAFSRFRRTLERQPLAAEDEPPEL----QRLRVQCVRLSRQLQVLNQR 1893
Cdd:TIGR02169  868 EELEELEAAL-----------RDLESRLGDLKKERDELEAQLRELERKIEELeaqiEKKRKRLSELKAKLEALEEE 932
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1632-1717 1.32e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1632 VRELQEENASLKAFLQNKEKEImcvsEQLEAQLAGMGSGALREVTYDRS-----SEIEELRSIIENLRENQQRLqKEKAE 1706
Cdd:COG2433    422 VERLEAEVEELEAELEEKDERI----ERLERELSEARSEERREIRKDREisrldREIERLERELEEERERIEEL-KRKLE 496

                           90
                   ....*....|.
gi 1953366521 1707 EMEQLHEVIER 1717
Cdd:COG2433    497 RLKELWKLEHS 507
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1421-1537 1.37e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.55  E-value: 1.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1421 EQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDE-EQLDEEVELLQEKLREKSDGFNElvikKELADRQVMIQE 1499
Cdd:COG2433    396 EAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAElEEKDERIERLERELSEARSEERR----EIRKDREISRLD 471

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1953366521 1500 EEIRRLEETNASCRREAAQLREELERQRDAMKALQQDK 1537
Cdd:COG2433    472 REIERLERELEEERERIEELKRKLERLKELWKLEHSGE 509
mukB PRK04863
chromosome partition protein MukB;
2594-2896 1.37e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.03  E-value: 1.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2594 EAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQ---------LQHLQREGQSSKTLEELRASLEKQfa 2664
Cdd:PRK04863   290 ELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASdhlnlvqtaLRQQEKIERYQADLEELEERLEEQ-- 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2665 qssQLCVALKHEQtakdnlQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERllTEQLSRGPRES 2743
Cdd:PRK04863   368 ---NEVVEEADEQ------QEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQAlER--AKQLCGLPDLT 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2744 PA-----HHALLRKLKE--EKSRAAELQARLEQVQRQQEADVQK--RRAELEREKEVRAAQAREPGRCLRREGHASQQqa 2814
Cdd:PRK04863   437 ADnaedwLEEFQAKEQEatEELLSLEQKLSVAQAAHSQFEQAYQlvRKIAGEVSRSEAWDVARELLRRLREQRHLAEQ-- 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2815 gLEPLQAGLAAQEGR----KDARR----------------ADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQR 2874
Cdd:PRK04863   515 -LQQLRMRLSELEQRlrqqQRAERllaefckrlgknlddeDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQA 593

                          330       340
                   ....*....|....*....|....
gi 1953366521 2875 TVQALEAKEEA--AQRPEAERLQE 2896
Cdd:PRK04863   594 RIQRLAARAPAwlAAQDALARLRE 617
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 949-1721 1.37e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.04  E-value: 1.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  949 LAELRQETGKQQLHCQEEPEVLECPSEPfLEQQILQPKGEFESEKKVALHEKEIHGlECAQAQSLYQKEKESLFLQLQEK 1028
Cdd:pfam02463  221 LEEEYLLYLDYLKLNEERIDLLQELLRD-EQEEIESSKQEIEKEEEKLAQVLKENK-EEEKEKKLQEEELKLLAKEEEEL 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1029 NNQILQLKEQILSLSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSdADLSDRERRALRDALRRLLSLFGEMLKVAIA 1108
Cdd:pfam02463  299 KSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE-LEIKREAEEEEEEELEKLQEKLEQLEEELLA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1109 LKSRISERVGLCLEDEDPPGAWPSGQALSAAPVLEETWPGSEAALLELDRSLPECVEMPSEAE-------ISSHICESFF 1181
Cdd:pfam02463  378 KKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIElkqgkltEEKEELEKQE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1182 MSPESSLEYEQPIRRIYQSLGLAVEGLLELALDSTRQLEEARQ----IHSRFEKEFSCKNEETAQVVRKQQQLLERLEE- 1256
Cdd:pfam02463  458 LKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQkeskARSGLKVLLALIKDGVGGRIISAHGRLGDLGVa 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1257 ----ENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLaeELEGLRQQLQQAAQQQAELKEENSALWSQKE 1332
Cdd:pfam02463  538 venyKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI--PKLKLPLKSIAVLEIDPILNLAQLDKATLEA 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1333 ASAAEAEAREAALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHL 1412
Cdd:pfam02463  616 DEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEIL 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1413 RSQ----RQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRVSDEEQLDEEvELLQEKLREKSDGFNELVIKK 1488
Cdd:pfam02463  696 RRQleikKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEE-KSRLKKEEKEEEKSELSLKEK 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1489 ELADRQV-----MIQEEEIRRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGrc 1563
Cdd:pfam02463  775 ELAEEREkteklKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLA-- 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1564 pvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASLK 1643
Cdd:pfam02463  853 ---------EEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1644 AFLQNKE--KEIMCVSEQLEAQLAGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEE 1721
Cdd:pfam02463  924 KEEAEILlkYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2615-2847 1.46e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2615 AALQELESERGKERALQSRLEEAQlQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRC 2694
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELE-KELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2695 EALLAQERGQLSELQRSLEAEKGRSL--------ELAAALRHERLLTEQlsrgpreSPAHHALLRKLKEEKSRAAELQAR 2766
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPlalllspeDFLDAVRRLQYLKYL-------APARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2767 LEQVQRQQE---ADVQKRRAELEREKEVRAAQAREPGRCLRREGHA----SQQQAGLEPLQAGLAAQEGRKDARRADVGP 2839
Cdd:COG4942    169 LEAERAELEallAELEEERAALEALKAERQKLLARLEKELAELAAElaelQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ....*...
gi 1953366521 2840 GRADAEMR 2847
Cdd:COG4942    249 AALKGKLP 256
PRK11281 PRK11281
mechanosensitive channel MscK;
2463-2737 1.90e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2463 VVQEQEKSLEHLRASDRSSllSEIQALRAQL-----RMThlQNQEKLQQLCAALTSA-------------EAR-GSRQEH 2523
Cdd:PRK11281    61 VQQDLEQTLALLDKIDRQK--EETEQLKQQLaqapaKLR--QAQAELEALKDDNDEEtretlstlslrqlESRlAQTLDQ 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2524 QLRRQVELLAYKVE------QEKRiasdVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQK 2597
Cdd:PRK11281   137 LQNAQNDLAEYNSQlvslqtQPER----AQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQR 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2598 EVLQLRSVLdskesnlraalQELESERGKERALQSRLEEAQLQHLQ------REGQSSKTLEELRASLEKQFAQSSQLcv 2671
Cdd:PRK11281   213 KSLEGNTQL-----------QDLLQKQRDYLTARIQRLEHQLQLLQeainskRLTLSEKTVQEAQSQDEAARIQANPL-- 279

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366521 2672 alkheqtakdnLQKELQIEASRCEALLAQERgQLSEL-QRSLEAEKgrslELAAALRHERLLTEQLS 2737
Cdd:PRK11281   280 -----------VAQELEINLQLSQRLLKATE-KLNTLtQQNLRVKN----WLDRLTQSERNIKEQIS 330
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2469-2897 2.01e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 2.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2469 KSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRR-----------QVELLAYKVE 2537
Cdd:pfam12128  268 KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAledqhgafldaDIETAAADQE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2538 QEKRIASDVQ------KTLTEEQ---EKASSVRKLLVVEQ--TVVRDLRSELRECKQDNERLLASL-GEAQKEVLQLRSV 2605
Cdd:pfam12128  348 QLPSWQSELEnleerlKALTGKHqdvTAKYNRRRSKIKEQnnRDIAGIKDKLAKIREARDRQLAVAeDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2606 LDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREgQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQK 2685
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLE-NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASE 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2686 ELQieasRCEALLAQERGQLSELQRSLEAEKGRSLE----------------LAAALRHERLLTEQLSRGPR-------- 2741
Cdd:pfam12128  507 ALR----QASRRLEERQSALDELELQLFPQAGTLLHflrkeapdweqsigkvISPELLHRTDLDPEVWDGSVggelnlyg 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2742 --------ESPAHHALLRKLKEEKSRAAE-LQARLEQVQRQQEADVQKRRA-ELEREKEVRAAQAREPGRcLRREGHASQ 2811
Cdd:pfam12128  583 vkldlkriDVPEWAASEEELRERLDKAEEaLQSAREKQAAAEEQLVQANGElEKASREETFARTALKNAR-LDLRRLFDE 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2812 QQAGLEPLQAGLAAQEGRKDARRADVgpgraDAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEA 2891
Cdd:pfam12128  662 KQSEKDKKNKALAERKDSANERLNSL-----EAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA 736


                   ....*.
gi 1953366521 2892 ERLQEE 2897
Cdd:pfam12128  737 AIAARR 742
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
164-314 2.18e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  164 KEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRlRCSQETAKLKEKL----QSEMERNARAVESL 239
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELE-RLEARLDALREELdeleAQIRGNGGDRLEQL 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  240 KRD---WESERGLCLENLRR--------ELSAKH-RSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEE 307
Cdd:COG4913    344 EREierLERELEERERRRARleallaalGLPLPAsAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE 423


                   ....*..
gi 1953366521  308 ALRQLRE 314
Cdd:COG4913    424 LEAEIAS 430
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2526-2785 2.27e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2526 RRQVELLAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVR------DLRSELRECkQDNERLLASLGEAQKEV 2599
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeiDVASAEREI-AELEAELERLDASSDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2600 LQLRSVLDSKESNLRAALQELESERGKERALQSRLEEA--QLQHLQR--EGQSSKTLEELRASLEKQFAQSSQlcvaLKH 2675
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAeeELDELQDrlEAAEDLARLELRALLEERFAAALG----DAV 763

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2676 EQTAKDNLQKE---LQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALR--HERLLTEQLsrgpresPAHHALL 2750
Cdd:COG4913    764 ERELRENLEERidaLRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLalLDRLEEDGL-------PEYEERF 836

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953366521 2751 RKLKEEKSRA--AELQARLeqvqRQQEADVQKRRAEL 2785
Cdd:COG4913    837 KELLNENSIEfvADLLSKL----RRAIREIKERIDPL 869
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1349-1740 2.50e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.81  E-value: 2.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1349 VECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQR------------ 1416
Cdd:pfam07888   57 REKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRaahearirelee 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1417 --QFMDEQAVEREHEREEFQREIQRLEEQLRQAArprphgprvSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQ 1494
Cdd:pfam07888  137 diKTLTQRVLERETELERMKERAKKAGAQRKEEE---------AERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQ 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1495 VMIQEEEIRRLEETNASCRREAAQ---LREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppadsc 1571
Cdd:pfam07888  208 VLQLQDTITTLTQKLTTAHRKEAEneaLLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQAR--------- 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1572 pegpevqLEAVQRALQQRESEvLDLKEQLGKMkddlvSKSDEVLHLNLELDAQSsraavsVRELQEENASLKAFLQNKEK 1651
Cdd:pfam07888  279 -------LQAAQLTLQLADAS-LALREGRARW-----AQERETLQQSAEADKDR------IEKLSAELQRLEERLQEERM 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1652 EimcvSEQLEAQLAGMGSGALREVTyDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEELSLGAPAVPA 1731
Cdd:pfam07888  340 E----REKLEVELGREKDCNRVQLS-ESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVADAKWSEAAL 414


                   ....*....
gi 1953366521 1732 AVDCELPAV 1740
Cdd:pfam07888  415 TSTERPDSP 423
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1427-1847 2.75e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 2.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1427 EHEREEFQREIQRLEEQLRQAARPRphgprvsdeeqldEEVELLQEKLREKSDGFNELvikkeladrqvmiqEEEIRRLE 1506
Cdd:PRK02224   212 ESELAELDEEIERYEEQREQARETR-------------DEADEVLEEHEERREELETL--------------EAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1507 ETNASCRREAAQLREELERQRDAmkalqqdkealqekqmsnlllVSTLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRAL 1586
Cdd:PRK02224   265 ETIAETEREREELAEEVRDLRER---------------------LEELEEERDDLLAEAGLDDADAEAVEARREELEDRD 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1587 QQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNleldaqsSRAAvsvrELQEENASLKAFLQNKEKEIMCVSEQLEAQLAG 1666
Cdd:PRK02224   324 EELRDRLEECRVAAQAHNEEAESLREDADDLE-------ERAE----ELREEAAELESELEEAREAVEDRREEIEELEEE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1667 MGSgaLREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQEelslgAPAVPAAVDCelpavpapavg 1746
Cdd:PRK02224   393 IEE--LRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-----AEALLEAGKC----------- 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1747 PEALAAAGAASRLFAEQEHRhgQALEALQQRLQAAEEAAAGQLAELERSAALREAE--VQAMASQIQAFEAALRAKEARL 1824
Cdd:PRK02224   455 PECGQPVEGSPHVETIEEDR--ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEdrIERLEERREDLEELIAERRETI 532

                          410       420
                   ....*....|....*....|...
gi 1953366521 1825 AERDLEIDAMKRQKLAHSAELET 1847
Cdd:PRK02224   533 EEKRERAEELRERAAELEAEAEE 555
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2585-2897 3.08e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2585 NER--LLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQ---------LQHLQREGQSSKTLE 2653
Cdd:COG3096    278 NERreLSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASdhlnlvqtaLRQQEKIERYQEDLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2654 ELRASLEKQfaqssQLCVALKHEQtakdnlQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRH-ERll 2732
Cdd:COG3096    358 ELTERLEEQ-----EEVVEEAAEQ------LAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQAlEK-- 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2733 TEQLSRGPRESPA-----HHALLRKLKE--EKSRAAELQARLEQVQRQQ-----------------EADVQKRRAELERE 2788
Cdd:COG3096    425 ARALCGLPDLTPEnaedyLAAFRAKEQQatEEVLELEQKLSVADAARRQfekayelvckiageverSQAWQTARELLRRY 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2789 KEVRAAQAREPG--RCLRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDE 2866
Cdd:COG3096    505 RSQQALAQRLQQlrAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELR 584

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1953366521 2867 HKIRQLQRTVQALEAKEEA--AQRPEAERLQEE 2897
Cdd:COG3096    585 QQLEQLRARIKELAARAPAwlAAQDALERLREQ 617
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1266-1907 3.20e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.76  E-value: 3.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1266 LELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQkeasaaeAEAREAAL 1345
Cdd:pfam12128  227 IRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQL-------LRTLDDQW 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1346 RREVECLTQEQSEARKQSEKDRA---ALLSQMKVFEAELEEQLSRHeacakqAEELSALRQQMAALDKHLRSQRQfmDEQ 1422
Cdd:pfam12128  300 KEKRDELNGELSAADAAVAKDRSeleALEDQHGAFLDADIETAAAD------QEQLPSWQSELENLEERLKALTG--KHQ 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1423 AVEREHER------EEFQREIQRLEEQL--------RQAARPRPHGPRVsdEEQLDEEVELLQEKLREKSDGFNELVIKK 1488
Cdd:pfam12128  372 DVTAKYNRrrskikEQNNRDIAGIKDKLakireardRQLAVAEDDLQAL--ESELREQLEAGKLEFNEEEYRLKSRLGEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1489 ELADRQVMIQEEEIRRLEETNASCRReaaqLREELERQRDAMKALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppa 1568
Cdd:pfam12128  450 KLRLNQATATPELLLQLENFDERIER----AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQ------ 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1569 DSCPEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKD-------DLVSKSDE--------VLHLNLELDA-QSSRAAVSV 1632
Cdd:pfam12128  520 SALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISpellhrtDLDPEVWDgsvggelnLYGVKLDLKRiDVPEWAASE 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1633 RELQEENASLKAFLQNKEKEIMCVSEQLeaqlaGMGSGALREVtydrSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1712
Cdd:pfam12128  600 EELRERLDKAEEALQSAREKQAAAEEQL-----VQANGELEKA----SREETFARTALKNARLDLRRLFDEKQSEKDKKN 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1713 EVIERLQEElslgapAVPAAVDCElpavpapavgpeaLAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAEL 1792
Cdd:pfam12128  671 KALAERKDS------ANERLNSLE-------------AQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1793 ERSAALREAEVQAMASQIQAFE-------AALRAKEARLAERDLEIDAMKRqKLAHSAELETILAAFSRFRR---TLERQ 1862
Cdd:pfam12128  732 ALLKAAIAARRSGAKAELKALEtwykrdlASLGVDPDVIAKLKREIRTLER-KIERIAVRRQEVLRYFDWYQetwLQRRP 810

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 1953366521 1863 PLAAEDEPPE--LQRLRVQCVRLSRQLQVLNQRFLRCQKEADKQQAR 1907
Cdd:pfam12128  811 RLATQLSNIEraISELQQQLARLIADTKLRRAKLEMERKASEKQQVR 857
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 169-439 3.21e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 3.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  169 ALTELRAMLNGRHAQELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAvESLKRDWESERG 248
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-EQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  249 LcLENLRRELSAKHRsELENLqdqfKRELSEQKAELEKIFQAKNQAECALRTLEAQ-HEEALRQLREDLQSERcQYVQDL 327
Cdd:TIGR02169  738 R-LEELEEDLSSLEQ-EIENV----KSELKELEARIEELEEDLHKLEEALNDLEARlSHSRIPEIQAELSKLE-EEVSRI 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  328 ELRLrdQEVEKQLELESLRASYAELKAQSQEEIRRLWSQLESPRPDRQDAS----------ARTPHGEELEQRERECGVQ 397
Cdd:TIGR02169  811 EARL--REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLngkkeeleeeLEELEAALRDLESRLGDLK 888

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1953366521  398 QQRRGRRA---EQESELGQSpEGAAERGREDPVLLEQRLQDATEE 439
Cdd:TIGR02169  889 KERDELEAqlrELERKIEEL-EAQIEKKRKRLSELKAKLEALEEE 932
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1207-1535 4.73e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.10  E-value: 4.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1207 GLLELALDSTRQLEEARQIHSRFEKEFscknEETAQVVRKQQQLLERLEEE-NAARTRL--MLELHQAQGIIEGFKEEKA 1283
Cdd:COG3096    282 ELSERALELRRELFGARRQLAEEQYRL----VEMARELEELSARESDLEQDyQAASDHLnlVQTALRQQEKIERYQEDLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1284 SLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEE----NSALWSQKEASAAEAEAREAALRREVEC----LTQE 1355
Cdd:COG3096    358 ELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQladyQQALDVQQTRAIQYQQAVQALEKARALCglpdLTPE 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1356 QSEARKQSEKDRAALLSQMKVfeaELEEQLSRHEACAKQAEELSALRQQMAAldkhlrsqrqfmdeqAVEREHEREEFQR 1435
Cdd:COG3096    438 NAEDYLAAFRAKEQQATEEVL---ELEQKLSVADAARRQFEKAYELVCKIAG---------------EVERSQAWQTARE 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1436 EIQRLEEQLRQAARPRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRRE 1515
Cdd:COG3096    500 LLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQ 579

                          330       340
                   ....*....|....*....|
gi 1953366521 1516 AAQLREELERQRDAMKALQQ 1535
Cdd:COG3096    580 RSELRQQLEQLRARIKELAA 599
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2454-2796 5.29e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.87  E-value: 5.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2454 SSLLERLEKVVQEQEKSLEHLRA--SDRSSLLSEiqalRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVEL 2531
Cdd:pfam05483  390 SSELEEMTKFKNNKEVELEELKKilAEDEKLLDE----KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTS 465

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2532 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVR---DLRSELRE-------CKQDNERLLASLGEAQKEVLQ 2601
Cdd:pfam05483  466 EEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQeasDMTLELKKhqediinCKKQEERMLKQIENLEEKEMN 545

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2602 LRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLE---KQFAQSSQLCVALKHEQT 2678
Cdd:pfam05483  546 LRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEnknKNIEELHQENKALKKKGS 625

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2679 AKDNLQKELQIEASRCEALLAQERGQLSEL----QRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPahhallrklK 2754
Cdd:pfam05483  626 AENKQLNAYEIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID---------K 696

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1953366521 2755 EEKSRAAELQARLEQVQRQQEADVQKRRAEL----EREKEVRAAQA 2796
Cdd:pfam05483  697 RCQHKIAEMVALMEKHKHQYDKIIEERDSELglykNKEQEQSSAKA 742
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1361-1720 5.32e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 5.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1361 KQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQ----AEELSALRQQMAALDKHLRSQR---QFMDEQAVEREHEREEF 1433
Cdd:TIGR04523  345 SQLKKELTNSESENSEKQRELEEKQNEIEKLKKEnqsyKQEIKNLESQINDLESKIQNQEklnQQKDEQIKKLQQEKELL 424

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1434 QREIQRLEEQLrqaarprphgprvsdeEQLDEEVELLQEKLREKSDGFNELVIKKEladrqvmIQEEEIRRLEETNASCR 1513
Cdd:TIGR04523  425 EKEIERLKETI----------------IKNNSEIKDLTNQDSVKELIIKNLDNTRE-------SLETQLKVLSRSINKIK 481

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1514 REAAQLREELERQRDAMKALQQDKEALQEKqmsnlllVSTLQSKLDEGrcpvppadscpegpEVQLEAVQRALQQRESEV 1593
Cdd:TIGR04523  482 QNLEQKQKELKSKEKELKKLNEEKKELEEK-------VKDLTKKISSL--------------KEKIEKLESEKKEKESKI 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1594 LDLKEQLGKMKDDLVSKS--DEVLHLNLELDaqssraavsvrELQEENASLKA-------FLQNKEKEIMCVSEQLEAQl 1664
Cdd:TIGR04523  541 SDLEDELNKDDFELKKENleKEIDEKNKEIE-----------ELKQTQKSLKKkqeekqeLIDQKEKEKKDLIKEIEEK- 608

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366521 1665 aGMGSGALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLHEVIERLQE 1720
Cdd:TIGR04523  609 -EKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPE 663
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2507-2745 5.36e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 5.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2507 LCAALTSAEARGSRQEHQLRRQvellaykvEQEKRIASdVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNE 2586
Cdd:COG4942      9 LLLALAAAAQADAAAEAEAELE--------QLQQEIAE-LEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2587 RLLASLGEAQKEVLQLRSVLDSKESNLR---AALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQF 2663
Cdd:COG4942     80 ALEAELAELEKEIAELRAELEAQKEELAellRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2664 AQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRES 2743
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239


                   ..
gi 1953366521 2744 PA 2745
Cdd:COG4942    240 AE 241
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 126-346 5.80e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 5.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  126 QQVQLQTQPVPSLELEALRLSLSNMHTAQleltQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELarEQHAR 205
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELES----KLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL--ESRLE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  206 EQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWESerglcLENLRRELSAKHRSELENLQDQFKRELSEQKAELE 285
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR-----RERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366521  286 KIFQAKNQAECALRTLE---AQHEEALRQLREDLQ--SERCQYVQDLELRLRD-QEVEKQLELESLR 346
Cdd:TIGR02168  451 ELQEELERLEEALEELReelEEAEQALDAAERELAqlQARLDSLERLQENLEGfSEGVKALLKNQSG 517
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2450-2911 5.98e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 5.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2450 PGEHSSLLERLEKVVQEQEKSLEHLRASdrSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2529
Cdd:TIGR00618  162 SKEKKELLMNLFPLDQYTQLALMEFAKK--KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQ 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2530 ELLAYKVEQEkriasdvqktltEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERL-----LASLGEAQKEVLQLRS 2604
Cdd:TIGR00618  240 QSHAYLTQKR------------EAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERInrarkAAPLAAHIKAVTQIEQ 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2605 VLDSKESNLRAALQELESERGKERALQSRLEEAQ-----LQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTA 2679
Cdd:TIGR00618  308 QAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEeqrrlLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2680 KDNLQKELQIEASRCEALLAQERGQLSELQRS-------LEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRK 2752
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFrdlqgqlAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2753 LKEEKSRAAELQARLEQVQR--QQEADVQKRRAELEREKEvraaqarepGRCLRREGHAsQQQAGLEPLQAGLAAQEgrk 2830
Cdd:TIGR00618  468 LKEREQQLQTKEQIHLQETRkkAVVLARLLELQEEPCPLC---------GSCIHPNPAR-QDIDNPGPLTRRMQRGE--- 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2831 dARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEaERLQEERLGLERVRQQLLC 2910
Cdd:TIGR00618  535 -QTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNIT-VRLQDLTEKLSEAEDMLAC 612


                   .
gi 1953366521 2911 A 2911
Cdd:TIGR00618  613 E 613
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2631-2995 5.99e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 5.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2631 QSRLEEAQlQHLQREGQsskTLEELRASLEKQFAQSSQlCVALKHEQTAKDNLQKELQIeasrceALLAQERGQLSELQR 2710
Cdd:TIGR02168  178 ERKLERTR-ENLDRLED---ILNELERQLKSLERQAEK-AERYKELKAELRELELALLV------LRLEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2711 SLEAEKGRSLELAAALRherLLTEQLSRGPRESPAHHALLRKLKEEKSRAAELQARLEQVQRQQeadvQKRRAELEREKE 2790
Cdd:TIGR02168  247 ELKEAEEELEELTAELQ---ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQIL----RERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2791 VRAAQAREPGR---CLRREGHASQQQagLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELELQRQRDEH 2867
Cdd:TIGR02168  320 ELEAQLEELESkldELAEELAELEEK--LEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2868 KIRQLQRTVQALEAKEEAAQRpEAERLQEERLGLERvrqQLLCAAGLLTSFISRTVDRTISDWTSSNEKAVTsLLHTLEE 2947
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLED-RRERLQQEIEELLK---KLEEAELKELQAELEELEEELEELQEELERLEE-ALEELRE 468

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2948 LKSELSTPSSSQKKMTAELQTQL--VDVLLKDNDSLTKALRTVTQEKAEL 2995
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARLdsLERLQENLEGFSEGVKALLKNQSGL 518
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2475-2706 6.16e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2475 RASDRSSLLSEIQALRAQLRmthlQNQEKLQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASDVQKTLTEEQ 2554
Cdd:COG4942     25 AEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2555 EKASSVRKLLVVEQTVVRDLRSEL---RECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQ 2631
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953366521 2632 SRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAL-LAQERGQLS 2706
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAgFAALKGKLP 256
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
224-635 7.52e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 7.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  224 KLQSEMER--NAR-AVESLKRDWESErglcLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRT 300
Cdd:PRK02224   163 KLEEYRERasDARlGVERVLSDQRGS----LDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  301 LE---AQHEEALRQLrEDLQSErcqyVQDLELRLRDQEVEKQL---ELESLRASYAELkaqsQEEIRRLWSQLESPRPDR 374
Cdd:PRK02224   239 ADevlEEHEERREEL-ETLEAE----IEDLRETIAETEREREElaeEVRDLRERLEEL----EEERDDLLAEAGLDDADA 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  375 QDASAR----TPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEPSLESGGIGPS 450
Cdd:PRK02224   310 EAVEARreelEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  451 SMREGERREQRVGPSLQPELAENHRCHLTAWTSSL---EAQQQAGLVETQESEGEQREGLSEGP----GQELTQVPVPCa 523
Cdd:PRK02224   390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELrerEAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVE- 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  524 qgtALKVDTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLENRnlHEKLQHEVCLKEDLERVKHSLVEDHREELKKAN 603
Cdd:PRK02224   469 ---TIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR--IERLEERREDLEELIAERRETIEEKRERAEELR 543

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1953366521  604 ERlqlvKQELKDKEAEWKVASEDLKRKAEEEL 635
Cdd:PRK02224   544 ER----AAELEAEAEEKREAAAEAEEEAEEAR 571
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 154-875 7.52e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 7.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  154 QLELTQANLQKeKETALTELRAMLNGRHAQ-ELALlrsrQQQELELAREQHAREQEEMRLrcsQETAKLKEKLQSEMERN 232
Cdd:TIGR02168  180 KLERTRENLDR-LEDILNELERQLKSLERQaEKAE----RYKELKAELRELELALLVLRL---EELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  233 ARAVESLKRDwESERGLCLENLRRElsakhRSELENLQDQFKRELSEQKAELEKIFQAKNQAECALRTLEAQHEEALRQL 312
Cdd:TIGR02168  252 EEELEELTAE-LQELEEKLEELRLE-----VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  313 REDLQS-----ERCQYVQDLELRLRDQEVEKQLELESLRASYAELKAQSQE------------------------EIRRL 363
Cdd:TIGR02168  326 EELESKldelaEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEleeqletlrskvaqlelqiaslnnEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  364 WSQLES--PRPDRQDASARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREDPVLLEQRLQDATEEps 441
Cdd:TIGR02168  406 EARLERleDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE-- 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  442 LESGGIGPSSMREGERREQRVGPSLQPELAENHRCHLTA------------WTSSLEA----QQQAGLVETQESEGEQRE 505
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlselisvdegYEAAIEAalggRLQAVVVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  506 GLSEGPGQELTQVPVPCAQGTALKVDTEVVARG----LGLEAEHRLKLLLLQTELKEEM------DVLKLENRNLHEKLQ 575
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNiegfLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  576 HEVCLKEDLERV------------KHSLVEDHREELKKANERLQLVKQELKDKEAEWKVAsedlkRKAEEELTLMLHDLK 643
Cdd:TIGR02168  644 GYRIVTLDGDLVrpggvitggsakTNSSILERRREIEELEEKIEELEEKIAELEKALAEL-----RKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  644 EQAEAEKQSV------INKFELREIKMRQLQDQQAAQILDLEGSLVEQQGRLRQLEHGLEAEECPRcghcgQEPAGRVAP 717
Cdd:TIGR02168  719 KELEELSRQIsalrkdLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI-----EELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  718 ADQDWELATRRLRE-DCALQLMQAQSRFLKERKELTEKFTAEQDALLQEAQEKHAcDMRLLQERHQQHVLSLTAQLEARR 796
Cdd:TIGR02168  794 LKEELKALREALDElRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE-ELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1953366521  797 RaEVEELKASVESERWALAEARvaELQTEHAAAISALEARHSALLGSLEsrhlsEVQAMREEHRQALEQLRVDLEKQLQ 875
Cdd:TIGR02168  873 S-ELEALLNERASLEEALALLR--SELEELSEELRELESKRSELRRELE-----ELREKLAQLELRLEGLEVRIDNLQE 943
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1230-1723 7.59e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 7.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1230 EKEFscknEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQ 1309
Cdd:PRK03918   199 EKEL----EEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1310 LQQAAQQQAELKEensalwsqkeasaaeaEAREAALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHE 1389
Cdd:PRK03918   275 IEELEEKVKELKE----------------LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1390 ACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGPRvsDEEQLDEEVEL 1469
Cdd:PRK03918   339 RLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEE--EISKITARIGE 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1470 LQEKLREKSDGFNEL--------VIKKELAD--RQVMIQE--EEIRRLEETNASCRREAAQLREELERQRdamKALQQDK 1537
Cdd:PRK03918   417 LKKEIKELKKAIEELkkakgkcpVCGRELTEehRKELLEEytAELKRIEKELKEIEEKERKLRKELRELE---KVLKKES 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1538 EALQEKQMSNLLlvSTLQSKLDegrcpvppadscpegpEVQLEAVQRALQQRESevldLKEQLGKMKDDLVSKSDEVLHL 1617
Cdd:PRK03918   494 ELIKLKELAEQL--KELEEKLK----------------KYNLEELEKKAEEYEK----LKEKLIKLKGEIKSLKKELEKL 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1618 NleldaqssraavsvrELQEENASLKAFLQNKEKEImcvsEQLEAQLAGMGSGALREVtydrSSEIEELRSIIE---NLR 1694
Cdd:PRK03918   552 E---------------ELKKKLAELEKKLDELEEEL----AELLKELEELGFESVEEL----EERLKELEPFYNeylELK 608

                          490       500
                   ....*....|....*....|....*....
gi 1953366521 1695 ENQQRLQKEKaEEMEQLHEVIERLQEELS 1723
Cdd:PRK03918   609 DAEKELEREE-KELKKLEEELDKAFEELA 636
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2448-2899 7.91e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 7.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2448 SAPGEHSSLLERLEkVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSA-----EARGSRQE 2522
Cdd:pfam15921  289 SARSQANSIQSQLE-IIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLAnseltEARTERDQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2523 H-----QLRRQVE-LLA--YKVEQEKRIASDVQKTLTEEQEKAS----SVRKLLVVEQTVVRDLRSELR----ECKQDNE 2586
Cdd:pfam15921  368 FsqesgNLDDQLQkLLAdlHKREKELSLEKEQNKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKamksECQGQME 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2587 RLLASL---GEAQKEVLQLRSVLDSKESNLRAALQEL--------ESERG----------KERA----------LQSR-- 2633
Cdd:pfam15921  448 RQMAAIqgkNESLEKVSSLTAQLESTKEMLRKVVEELtakkmtleSSERTvsdltaslqeKERAieatnaeitkLRSRvd 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2634 LEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNLQKE-------LQIEASRCEALLAQERGQLS 2706
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQLEKEINDRRLELQ 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2707 ELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRE--------SPAHHALLRKLKEEKSRAAELQARLEQVQR------ 2772
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSErlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnks 687

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2773 -QQEADVQKRRAELeREKEVRAAQAREPGRCLR-REGHASQQQAGlepLQAGLAAQEGRKDARRADVgpgRADAEMRPTG 2850
Cdd:pfam15921  688 eEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEgSDGHAMKVAMG---MQKQITAKRGQIDALQSKI---QFLEEAMTNA 760

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1953366521 2851 AKEK--LRElelqrqrDEHKIRQLQRTVQAleAKEEAAQRPEAERLQEERL 2899
Cdd:pfam15921  761 NKEKhfLKE-------EKNKLSQELSTVAT--EKNKMAGELEVLRSQERRL 802
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2421-2893 9.72e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.17  E-value: 9.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2421 EFLQAVQEAFGKEREMlRAELQPRPcgsapGEHSSLLERLEKVVQEQEKSLEHLRaSDRSSLLSEIQALRAQLRmthlQN 2500
Cdd:pfam01576   47 EQLQAETELCAEAEEM-RARLAARK-----QELEEILHELESRLEEEEERSQQLQ-NEKKKMQQHIQDLEEQLD----EE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2501 QEKLQQLCAALTSAEARGSRQEHQL----RRQVELLAYKVEQEKRIaSDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRS 2576
Cdd:pfam01576  116 EAARQKLQLEKVTTEAKIKKLEEDIllleDQNSKLSKERKLLEERI-SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEE 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2577 ELRECKQDNERLLAS--------------LGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEE--AQLQ 2640
Cdd:pfam01576  195 RLKKEEKGRQELEKAkrklegestdlqeqIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIREleAQIS 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2641 HLQREGQSSKTleeLRASLEKQFAQSSQLCVALKHEqtakdnLQKELQIEASRCEaLLAQERGQLSELQRSLEAEKGRSL 2720
Cdd:pfam01576  275 ELQEDLESERA---ARNKAEKQRRDLGEELEALKTE------LEDTLDTTAAQQE-LRSKREQEVTELKKALEEETRSHE 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2721 ELAAALRHERL-----LTEQLSRGPRESPAHHALLRKLKEEKsraAELQARLEQVQrQQEADVQKRRAELEREKEVRAAQ 2795
Cdd:pfam01576  345 AQLQEMRQKHTqaleeLTEQLEQAKRNKANLEKAKQALESEN---AELQAELRTLQ-QAKQDSEHKRKKLEGQLQELQAR 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2796 AREPGRC-LRREGHASQQQAGLEPLQAGLAAQEGRKDARRADVgpgrADAEMRPTGAKEKLRELELQRQRDEHKIRQLQR 2874
Cdd:pfam01576  421 LSESERQrAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV----SSLESQLQDTQELLQEETRQKLNLSTRLRQLED 496

                          490       500
                   ....*....|....*....|.
gi 1953366521 2875 TVQALEAK--EEAAQRPEAER 2893
Cdd:pfam01576  497 ERNSLQEQleEEEEAKRNVER 517
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1373-1546 9.93e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 9.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1373 QMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLR--SQRQFMDEQAVEREHEREEFQREIQR----------L 1440
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAELERldassddlaaL 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1441 EEQLRQAarprphgprVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQV-----MIQEEEIRRLEET--NASCR 1513
Cdd:COG4913    691 EEQLEEL---------EAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLeaaedLARLELRALLEERfaAALGD 761

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1953366521 1514 REAAQLREELERQRDAMKALQQDKEALQEKQMS 1546
Cdd:COG4913    762 AVERELRENLEERIDALRARLNRAEEELERAMR 794
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1251-1962 1.00e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.11  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1251 LERLEEENAARTRLMLELHQAQgiiegfkeekaslqealCRQETAEHGLaeELEGLRQQLQQAAQQQAELKEENSALWSQ 1330
Cdd:pfam15921  247 LEALKSESQNKIELLLQQHQDR-----------------IEQLISEHEV--EITGLTEKASSARSQANSIQSQLEIIQEQ 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1331 KEASAAEAEAREAALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAAlDK 1410
Cdd:pfam15921  308 ARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLA-DL 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1411 HLRSQRQFMDEQAVER------------EHEREEF---QREIQRLEEQL------------RQAARPRPHGPRVSDEEQL 1463
Cdd:pfam15921  387 HKREKELSLEKEQNKRlwdrdtgnsitiDHLRRELddrNMEVQRLEALLkamksecqgqmeRQMAAIQGKNESLEKVSSL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1464 DEEVELLQEKLREKSDgfnELVIKK--------ELADRQVMIQEEEiRRLEETNAscrrEAAQLREELERQRDAMKALQQ 1535
Cdd:pfam15921  467 TAQLESTKEMLRKVVE---ELTAKKmtlesserTVSDLTASLQEKE-RAIEATNA----EITKLRSRVDLKLQELQHLKN 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1536 DKEALQEkqmsnlllvstLQSKLDEGRCPVPPADSCPEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVL 1615
Cdd:pfam15921  539 EGDHLRN-----------VQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1616 HLNLELDAQSSRaavsVRELQEENASLKAflqNKEKEIMCVSEQLEaqlagmgsgALREVTYDRS---SEIEELRSIIEN 1692
Cdd:pfam15921  608 EFKILKDKKDAK----IRELEARVSDLEL---EKVKLVNAGSERLR---------AVKDIKQERDqllNEVKTSRNELNS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1693 LRENQQRLQKEKAEEMEQLHEVIERLQEELSlgapavpaavdcelpavpapavgpEALAAAGAASRLFAEQEHRHGQALE 1772
Cdd:pfam15921  672 LSEDYEVLKRNFRNKSEEMETTTNKLKMQLK------------------------SAQSELEQTRNTLKSMEGSDGHAMK 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1773 AlqqrlqaaeeaaagqLAELERSAALREAEVQAMASQIQAFEAAlrakearLAERDLEIDAMKRQKLAHSAELETIlaaf 1852
Cdd:pfam15921  728 V---------------AMGMQKQITAKRGQIDALQSKIQFLEEA-------MTNANKEKHFLKEEKNKLSQELSTV---- 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1853 srfrrTLERQPLAAEDEPPELQ--RLRVQCVRLSRQLQVLNQRFLRCQKEADKQQARGARLRPR---GARGLQGPG---- 1923
Cdd:pfam15921  782 -----ATEKNKMAGELEVLRSQerRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQhtlDVKELQGPGytsn 856

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 1953366521 1924 ----PRAEEASRDEASQQDVDSRQVASATQGQVRDPQNAVNDD 1962
Cdd:pfam15921  857 ssmkPRLLQPASFTRTHSNVPSSQSTASFLSHHSRKTNALKED 899
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1352-1863 1.02e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1352 LTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALD---KHLRSQRQFMD--EQAVER 1426
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEaelEELREELEKLEklLQLLPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1427 EHEREEFQREIQRLEEQLRQAARprphgpRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQ-EEEIRRL 1505
Cdd:COG4717    131 YQELEALEAELAELPERLEELEE------RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDlAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1506 EETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQ-----------MSNLLLVSTLQSKLDEGRCPVPPADSCPEG 1574
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlkearlllliAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1575 P---EVQLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVS-VRELQEENASLKAflQNKE 1650
Cdd:COG4717    285 LlalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDrIEELQELLREAEE--LEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1651 KEIMCVSEQLEAQLAGMGSgalrevtydrsSEIEELRSIIENLRENQQRLQKekaeemeqlhevIERLQEELSLGAPAVP 1730
Cdd:COG4717    363 LQLEELEQEIAALLAEAGV-----------EDEEELRAALEQAEEYQELKEE------------LEELEEQLEELLGELE 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1731 AAVDCELPAvpapavgpealaaagaasrlfaeqehrhgqALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMASqi 1810
Cdd:COG4717    420 ELLEALDEE------------------------------ELEEELEELEEELEELEEELEELREELAELEAELEQLEE-- 467

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1953366521 1811 qafEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRtlERQP 1863
Cdd:COG4717    468 ---DGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE--ERLP 515
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2452-2896 1.05e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2452 EHSSLLERLEKVVQEQEKSLEHLRA--SDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQV 2529
Cdd:PRK02224   245 EHEERREELETLEAEIEDLRETIAEteREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2530 ELLAYKVEQEKRI-------------ASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQ 2596
Cdd:PRK02224   325 ELRDRLEECRVAAqahneeaeslredADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2597 KEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAqlQHLQREG----------------------QSSKTLEE 2654
Cdd:PRK02224   405 VDLGNAEDFLEELREERDELREREAELEATLRTARERVEEA--EALLEAGkcpecgqpvegsphvetieedrERVEELEA 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2655 LRASLEKQFAQSSQLCVALKHEQTAKDNLQKeLQIEASRCEALLAQERGQLSELQRSLEAEKGRSLEL-AAALRHERLLT 2733
Cdd:PRK02224   483 ELEDLEEEVEEVEERLERAEDLVEAEDRIER-LEERREDLEELIAERRETIEEKRERAEELRERAAELeAEAEEKREAAA 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2734 EQLSRGPRESPAHHALLRKLKEEKSR------AAELQARLEQVQRQQEADVQKR--RAELEREKEVRAAQAREPGRCLR- 2804
Cdd:PRK02224   562 EAEEEAEEAREEVAELNSKLAELKERieslerIRTLLAAIADAEDEIERLREKReaLAELNDERRERLAEKRERKRELEa 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2805 --REGHASQQQAGLEPLQAGLAAQEGRKDARRADvgpgRADAEMRPTGAKEKLRELElqRQRDEHKirQLQRTVQALEAK 2882
Cdd:PRK02224   642 efDEARIEEAREDKERAEEYLEQVEEKLDELREE----RDDLQAEIGAVENELEELE--ELRERRE--ALENRVEALEAL 713

                          490
                   ....*....|....
gi 1953366521 2883 EEaaqrpEAERLQE 2896
Cdd:PRK02224   714 YD-----EAEELES 722
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2460-2734 1.15e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2460 LEKVVQEQEKSLEHLRasdrsSLLSEIQALRAQLRMTHLQNQEKLQQLcaaltsaeaRGSRQEHQ-LRRQVELLAYKVEQ 2538
Cdd:TIGR04523  372 IEKLKKENQSYKQEIK-----NLESQINDLESKIQNQEKLNQQKDEQI---------KKLQQEKElLEKEIERLKETIIK 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2539 EKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQ 2618
Cdd:TIGR04523  438 NNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTK 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2619 ELESERGKERALQSRLEEAQLQHLQREGQSSKTLEEL-RASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEAL 2697
Cdd:TIGR04523  518 KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKE 597

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953366521 2698 LAQERGQLSELQRSLEaEKGRSLELAAAlRHERLLTE 2734
Cdd:TIGR04523  598 KKDLIKEIEEKEKKIS-SLEKELEKAKK-ENEKLSSI 632
PTZ00121 PTZ00121
MAEBL; Provisional
 1213-1715 1.16e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1213 LDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTrlmlELHQAQgiiegfkEEKASLQEAlcRQ 1292
Cdd:PTZ00121  1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKAD----ELKKAA-------AAKKKADEA--KK 1425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1293 ETAEHGLAEELEglrqqlqqaaQQQAELKEENSALWSQKEASAAEAEAREAALRREVECLTQEQSEARKQSEKDRAALLS 1372
Cdd:PTZ00121  1426 KAEEKKKADEAK----------KKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA 1495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1373 QMKVFEAELEEQLSRHEACAKQAEELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQR---EIQRLEEQLRQAAR 1449
Cdd:PTZ00121  1496 KKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKkaeEKKKAEEAKKAEED 1575

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1450 PRPHGPRVSDEEQLDEEVELLQEKLREKSDGFNELVIKKELADRqvmIQEEEIRRLEETnascRREAAQLREELERQRda 1529
Cdd:PTZ00121  1576 KNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK---IKAEELKKAEEE----KKKVEQLKKKEAEEK-- 1646

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1530 mkalqQDKEALQEKQMSNLLLVSTLQSKLDEGRCPVPPADSCPEGPEVQLEAVQR-ALQQRESEVLDLKEQLGKMKDDLV 1608
Cdd:PTZ00121  1647 -----KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKeAEEAKKAEELKKKEAEEKKKAEEL 1721

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1609 SKSDEVLHLNLE-LDAQSSRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGSGaLREVTYDRSSEIEE-- 1685
Cdd:PTZ00121  1722 KKAEEENKIKAEeAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE-LDEEDEKRRMEVDKki 1800

                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 1953366521 1686 ------LRSIIENLRENQQRLQKEKAEEMEQLHEVI 1715
Cdd:PTZ00121  1801 kdifdnFANIIEGGKEGNLVINDSKEMEDSAIKEVA 1836
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1633-1866 1.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1633 RELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMGsgALREVTYDRSSEIEELRSIIENLRENQQRLQKEKAEEMEQLH 1712
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIA--ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1713 EVIERLQEELSLGAPAVPAAVDcelpavpapavGPEALAAAGAASRLFAEQEHRHGQALEALQQRLQAAEEAAAGQLAEL 1792
Cdd:COG4942    108 ELLRALYRLGRQPPLALLLSPE-----------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366521 1793 ERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEIDAMKRQKLAHSAELETILAAFSRFRRTLERQPLAA 1866
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 184-877 1.42e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  184 ELALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEKLQSEMERNARAVESLKRDWESErglclENLRRELsakhr 263
Cdd:TIGR00618  180 QLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSH-----AYLTQKR----- 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  264 sELENLQDQFKRELSEQKAELEKifqaknqaecaLRTLEAQHEEALRQLREDLQSERCQYVQDLELRLRDQEVEKQLELE 343
Cdd:TIGR00618  250 -EAQEEQLKKQQLLKQLRARIEE-----------LRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  344 SLRASYAELKAQSQEeirrlwSQLESPRPDRQDASARTPHGEELEQReRECGVQQQRRGRRAEQESELgqSPEGAAERGR 423
Cdd:TIGR00618  318 SKMRSRAKLLMKRAA------HVKQQSSIEEQRRLLQTLHSQEIHIR-DAHEVATSIREISCQQHTLT--QHIHTLQQQK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  424 EDPVLLEQRLQDATEEPSLESGGIGPSSMREGERREQRVGPSLQPELAENHRCHLTAWTSSLEAQQQAGLVETQESEGEQ 503
Cdd:TIGR00618  389 TTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  504 REGLsegpgQELTQVPVPCAQGTALKvdTEVVARGLGLEAEHRLKLLLLQTELKEEMDVLKLE--NRNLHEKLQHEVCLK 581
Cdd:TIGR00618  469 KERE-----QQLQTKEQIHLQETRKK--AVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGplTRRMQRGEQTYAQLE 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  582 EDLERVKHSLVEDhREELKKANERLQLVKQELKDKEAEWKVASEDLKrKAEEELTLMLHDLKEQAEAEKQsvinKFELRE 661
Cdd:TIGR00618  542 TSEEDVYHQLTSE-RKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP-NLQNITVRLQDLTEKLSEAEDM----LACEQH 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  662 IKMRQLQDQQAAQILDLEGSLVEQqgRLRQLEHGLEAEEcprcghcgqepagrVAPADQDWELATRRLREDCALQLMQAQ 741
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRLHLQQCSQ--ELALKLTALHALQ--------------LTLTQERVREHALSIRVLPKELLASRQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  742 SRFLKERKELTE----KFTAEQDALLQEAQEKHACDMRLLQERHQQHVLSLTAQLEARRRAEVEELKASVESERWALAEA 817
Cdd:TIGR00618  680 LALQKMQSEKEQltywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKAR 759

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  818 RVAELQTEHAAAIsalearhsALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEK 877
Cdd:TIGR00618  760 TEAHFNNNEEVTA--------ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE 811
PTZ00121 PTZ00121
MAEBL; Provisional
 2428-2660 1.50e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.75  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2428 EAFGKEREMLRAELQPRpcgsAPGEHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALR----AQLRMTHLQNQEK 2503
Cdd:PTZ00121  1555 EELKKAEEKKKAEEAKK----AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKkaeeAKIKAEELKKAEE 1630

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2504 LQQLCAALTSAEARGSRQEHQLRRQVELLAYKVEQEKRIASdvqktltEEQEKASSVRKLLVVEQTVVRDLRSELREcKQ 2583
Cdd:PTZ00121  1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE-------EDKKKAEEAKKAEEDEKKAAEALKKEAEE-AK 1702

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2584 DNERLLASLGEAQKEVLQLRSvlDSKESNLRAALQELESERGKERALQSRLEEAQ---LQHLQREGQssKTLEELRASLE 2660
Cdd:PTZ00121  1703 KAEELKKKEAEEKKKAEELKK--AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEkkkIAHLKKEEE--KKAEEIRKEKE 1778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2686-2970 1.53e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2686 ELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRK----LKEEKSRAA 2761
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAeveqLEERIAQLS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2762 ELQARLEQVQRQQEADVQKRRAELEREKEVRAAQARepgrclRREGHASQQQAGLEPLQAgLAAQEGRKDARRADVGPGR 2841
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEA------QIEQLKEELKALREALDE-LRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2842 ADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRpEAERLQEERLGLERVRQQLLCAAglltsfisR 2921
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES-ELEALLNERASLEEALALLRSEL--------E 897

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1953366521 2922 TVDRTISDWtssnEKAVTSLLHTLEELKSELSTPSSSQKKMTAELQTQL 2970
Cdd:TIGR02168  898 ELSEELREL----ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
164-700 1.57e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 1.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  164 KEKETALTELRAMLNG--RHAQELALLRSR--QQQELELAREQHAREQEEmRLRCSQETAKLKEKLQSEMERNARAVESL 239
Cdd:PRK03918   210 NEISSELPELREELEKleKEVKELEELKEEieELEKELESLEGSKRKLEE-KIRELEERIEELKKEIEELEEKVKELKEL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  240 KrdWESERGLCLENLRRELS----------AKHRSELENLQDQFKrELSEQKAELEKIFQAKNQAECALRTLEAQHE--E 307
Cdd:PRK03918   289 K--EKAEEYIKLSEFYEEYLdelreiekrlSRLEEEINGIEERIK-ELEEKEERLEELKKKLKELEKRLEELEERHElyE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  308 ALRQLREDLQSercqyvqdLELRLRDQEVEK-QLELESLRASYAELKaQSQEEIRRLWSQLESPRPDRQDASartphgEE 386
Cdd:PRK03918   366 EAKAKKEELER--------LKKRLTGLTPEKlEKELEELEKAKEEIE-EEISKITARIGELKKEIKELKKAI------EE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  387 LEQRERECGVQqqrrGRRAEQESELGQSPEGAAERGRedpvlLEQRLQDATEEpslesggigpssMREGERREQRVGPSL 466
Cdd:PRK03918   431 LKKAKGKCPVC----GRELTEEHRKELLEEYTAELKR-----IEKELKEIEEK------------ERKLRKELRELEKVL 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  467 --QPELAENHRchLTAWTSSLEAQQQAGLVETQESEGEQREGLSEgpgqeltqvpvpcaqgTALKVDTEVvaRGLGLEAE 544
Cdd:PRK03918   490 kkESELIKLKE--LAEQLKELEEKLKKYNLEELEKKAEEYEKLKE----------------KLIKLKGEI--KSLKKELE 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  545 HRLKLLLLQTELKEEMDVLKLENRNLHEKLQHE--VCLKEDLERVKhSLVEDHRE--ELKKANERLQLVKQELKDKEAEW 620
Cdd:PRK03918   550 KLEELKKKLAELEKKLDELEEELAELLKELEELgfESVEELEERLK-ELEPFYNEylELKDAEKELEREEKELKKLEEEL 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  621 KVASEDLKR--KAEEELTlmlhdlKEQAEAEKQSVINKFELREIKMRQLQDQQA---AQILDLEGSLVEQQGRLRQLEHG 695
Cdd:PRK03918   629 DKAFEELAEteKRLEELR------KELEELEKKYSEEEYEELREEYLELSRELAglrAELEELEKRREEIKKTLEKLKEE 702


                   ....*
gi 1953366521  696 LEAEE 700
Cdd:PRK03918   703 LEERE 707
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2809-3005 1.64e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2809 ASQQQAGLEPLQAGLAAQEGRKD---ARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEA 2885
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAalkKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2886 AQRPEAERLQE-ERLGLERVRQQLLCAAGLLTSFISRTVDRTISDWTSSNEKAVTSLLHTLEELKSELSTPSSSQKKMTA 2964
Cdd:COG4942    102 QKEELAELLRAlYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1953366521 2965 ELQTQLVDvLLKDNDSLTKALRTVTQEKAELCRAVSQLEKS 3005
Cdd:COG4942    182 ELEEERAA-LEALKAERQKLLARLEKELAELAAELAELQQE 221
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2566-2896 1.82e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 1.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2566 VEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEE---AQLQHL 2642
Cdd:pfam02463  153 ERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEeylLYLDYL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2643 QREGQSSKTLEELRASLEKQFAQSSQLCVAlkheQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKgRSLEL 2722
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEK----EEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEL-LKLER 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2723 aaalrherllteqlsrgprespAHHALLRKLKEEKSRAAELQARLEQVQRQQEAdvqkRRAELEREKEVRAAQAREPGRC 2802
Cdd:pfam02463  308 ----------------------RKVDDEEKLKESEKEKKKAEKELKKEKEEIEE----LEKELKELEIKREAEEEEEEEL 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2803 LRREGHASQQQAGLEPLQAGLAAQEGRKDARRadvgpgradaemrptGAKEKLRELELQRQRDEHKIRQLQRTVQALEAK 2882
Cdd:pfam02463  362 EKLQEKLEQLEEELLAKKKLESERLSSAAKLK---------------EEELELKSEEEKEAQLLLELARQLEDLLKEEKK 426

                          330
                   ....*....|....
gi 1953366521 2883 EEAAQRPEAERLQE 2896
Cdd:pfam02463  427 EELEILEEEEESIE 440
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1227-1653 1.90e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1227 SRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLElhqaqgiiegFKEEKASLQEALCRQETAEHGLAEELEGL 1306
Cdd:pfam02463  165 SRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQ----------AKKALEYYQLKEKLELEEEYLLYLDYLKL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1307 RQQLQQAAQQQAELKEENSALWSQKEASAAEAEAREAALRREVECLTQEQSEARKQSEKDRAALLSQM---KVFEAELEE 1383
Cdd:pfam02463  235 NEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELlklERRKVDDEE 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1384 QLSRHEACAKQAE-ELSALRQQMAALDKHLRSQrqfmdEQAVEREHEREEFQREIQRLEEQLRQAARPRPHGprvsDEEQ 1462
Cdd:pfam02463  315 KLKESEKEKKKAEkELKKEKEEIEELEKELKEL-----EIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL----ESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1463 LDEEVELLQEKLREKSDGFNELVIKKELADRQVMIQEEEI-----------RRLEETNASCRREAAQLREELERQRDAMK 1531
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKkeeleileeeeESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1532 ALQQDKEALQEKQMSNLLLVSTLQSKLDEGRcpvppADSCPEGPEVQLEAVQRALQQREsEVLDLKEQLGKMKDDLVSKS 1611
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLE-----ERSQKESKARSGLKVLLALIKDG-VGGRIISAHGRLGDLGVAVE 539

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1953366521 1612 DEVLHLNLELDAQSSRAAVSVRELQEENASLKAFLQNKEKEI 1653
Cdd:pfam02463  540 NYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLR 581
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 797-1447 2.12e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  797 RAEVEELKASVESERWALAEARVAELQTEHAAAISALEArhsallgslESRHLSEVQAMREEHRQALEQLRVDLEKQLQE 876
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEE---------LEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  877 KEAshptpltqalekhplsHGQELPPVEGGLRtqtssgqlegvkapvpPEVQGAQQegapvpAEVEAQRpaLLAELRQET 956
Cdd:COG1196    290 EYE----------------LLAELARLEQDIA----------------RLEERRRE------LEERLEE--LEEELAELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  957 GKQQLHCQEEPEVLEcpsepflEQQILQPKgefESEKKVALHEKEihglecaQAQSLYQKEKESLFLQLQEKNNQILQLK 1036
Cdd:COG1196    330 EELEELEEELEELEE-------ELEEAEEE---LEEAEAELAEAE-------EALLEAEAELAEAEEELEELAEELLEAL 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1037 EQILSLSHEVEERRRDLEQLQQRRERENQEGTNLISMLKSDADLSDRERRALRDALRRLLSLFGEMLKVAIALKSRISER 1116
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1117 VGLCLEDED----------------PPGAWPSGQALSAAPVLEETWPGSEAALLELDRSLPECVEMPSEAEISSHICESF 1180
Cdd:COG1196    473 ALLEAALAElleelaeaaarlllllEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1181 FMSPESSLEYEQPIRRiyqsLGLAVEGLLELALDSTRQLEEARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAA 1260
Cdd:COG1196    553 VEDDEVAAAAIEYLKA----AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1261 RTRLMLELHQAQGIIEGFKEEKASLQEALCRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALWSQKEASAAEAEA 1340
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1341 REAALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEEQLSRHEAC---AKQAEELSALRQQ--------MAALD 1409
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpdlEELERELERLEREiealgpvnLLAIE 788

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 1953366521 1410 --KHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQA 1447
Cdd:COG1196    789 eyEELEERYDFLSEQREDLEEARETLEEAIEEIDRETRER 828
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 251-319 2.22e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 43.66  E-value: 2.22e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366521  251 LENLRRELSAKHRsELENL---QDQFKRELSEQKAELEKIFQ-----AKNQAECALRTLEAQHEEALRQLREDLQSE 319
Cdd:PRK00409   525 LEELERELEQKAE-EAEALlkeAEKLKEELEEKKEKLQEEEDklleeAEKEAQQAIKEAKKEADEIIKELRQLQKGG 600
PRK10361 PRK10361
DNA recombination protein RmuC; Provisional
 1359-1524 2.29e-03

DNA recombination protein RmuC; Provisional


Pssm-ID: 182409 [Multi-domain]  Cd Length: 475  Bit Score: 43.43  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1359 ARKQSEKDRAALLSQMKVFEAEL---EEQLSRHEACAKQAE----ELSALRQQMAALDKHLRSQRQFMDEQAVEREHERE 1431
Cdd:PRK10361    23 ASYQHAQQKAEQLAEREEMVAELsaaKQQITQSEHWRAECEllnnEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1432 EFQREIQRLEEQLRQAA-RPRPHGPRVSDeEQLDEEVELLQEKLREKSDGFNELV---IKKELADRQVMIQeeEIRRLEE 1507
Cdd:PRK10361   103 QMINSEQRLSEQFENLAnRIFEHSNRRVD-EQNRQSLNSLLSPLREQLDGFRRQVqdsFGKEAQERHTLAH--EIRNLQQ 179

                          170
                   ....*....|....*..
gi 1953366521 1508 TNASCRREAAQLREELE 1524
Cdd:PRK10361   180 LNAQMAQEAINLTRALK 196
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1430-1610 2.45e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 2.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1430 REEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLR--EKSDGFNELVIKKELADRQVMIQEEEIRRLEE 1507
Cdd:COG4913    612 LAALEAELAELEEELAEAEE---------RLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1508 TN----------ASCRREAAQLREELERQRDAMKALQQDKEALQEkqmsnllLVSTLQSKLDEgrcpvpPADSCPEGPEV 1577
Cdd:COG4913    683 SSddlaaleeqlEELEAELEELEEELDELKGEIGRLEKELEQAEE-------ELDELQDRLEA------AEDLARLELRA 749

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1953366521 1578 QLEAVQRALQQRESEvLDLKEQLGKMKDDLVSK 1610
Cdd:COG4913    750 LLEERFAAALGDAVE-RELRENLEERIDALRAR 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2452-2790 2.50e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 2.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2452 EHSSLLERLEKVVQEQEKSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTSAEARGSRQEHQLRRQVEL 2531
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2532 -----------LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVL 2600
Cdd:COG1196    523 agavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2601 QLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAK 2680
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2681 DNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKEEKSRA 2760
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1953366521 2761 AELQARLEQVQRQQEA-------------DVQKRRAELEREKE 2790
Cdd:COG1196    763 EELERELERLEREIEAlgpvnllaieeyeELEERYDFLSEQRE 805
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1678-1949 3.09e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 3.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1678 DRSSEIEELRSIIENLRENQQRLQKEKAE---EMEQLHEVIERLQEELSlgapavpaavdcelpavpapAVGPEALAAAG 1754
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAEleaELEELRLELEELELELE--------------------EAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1755 AASRLFAEQEHRHG--QALEALQQRLQAAEEAAAGQLAELERSAALREAEVQAMASQIQAFEAALRAKEARLAERDLEID 1832
Cdd:COG1196    296 ELARLEQDIARLEErrRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1833 AMKRQKLAHSAELETILAAFSRFRRTLERQPLAAEDEPPELQRLRVQCVRLSRQLQVLNQRFLRCQKEADKQQARGARLR 1912
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1953366521 1913 pRGARGLQGPGPRAEEASRDEASQQDVDSRQVASATQ 1949
Cdd:COG1196    456 -EEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 1369-1600 3.32e-03

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 43.30  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1369 ALLSQMKVFEAELEEQLSRHEACAKQAE-ELSALRQQMAALDKHLRSQRQfmdeqaverehEREEFQREIQRLEEQLRQA 1447
Cdd:pfam09726  409 AELQASRQTEQELRSQISSLTSLERSLKsELGQLRQENDLLQTKLHNAVS-----------AKQKDKQTVQQLEKRLKAE 477

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1448 ARPRphgprVSDEEQLDEE--------------VELLQEKLREKSDGFN------ELVIKKelADRQVMIQEEEIRRLEE 1507
Cdd:pfam09726  478 QEAR-----ASAEKQLAEEkkrkkeeeataaraVALAAASRGECTESLKqrkrelESEIKK--LTHDIKLKEEQIRELEI 550

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1508 tnascrrEAAQLREELERQRDA---MKALQ--QDKEALQEKQMSnlllvSTLQSKLDegrcpvppADSCPEGPEVQLEAV 1582
Cdd:pfam09726  551 -------KVQELRKYKESEKDTevlMSALSamQDKNQHLENSLS-----AETRIKLD--------LFSALGDAKRQLEIA 610

                          250
                   ....*....|....*...
gi 1953366521 1583 QRALQQRESEVLDLKEQL 1600
Cdd:pfam09726  611 QGQIYQKDQEIKDLKQKI 628
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2582-2841 3.32e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2582 KQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEK 2661
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2662 QFAQSSQLCVALkheqtAKDNLQKELQIEASRCEALLAQERGQLseLQRSLEAEKGRSLELAAALRHERLLTEQLSrgpr 2741
Cdd:COG4942    102 QKEELAELLRAL-----YRLGRQPPLALLLSPEDFLDAVRRLQY--LKYLAPARREQAEELRADLAELAALRAELE---- 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2742 espahhALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREpgrclrreghASQQQAGLEPLQA 2821
Cdd:COG4942    171 ------AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE----------AEELEALIARLEA 234

                          250       260
                   ....*....|....*....|
gi 1953366521 2822 GLAAQEGRKDARRADVGPGR 2841
Cdd:COG4942    235 EAAAAAERTPAAGFAALKGK 254
COG3903 COG3903
Predicted ATPase [General function prediction only];
2574-2915 3.49e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 43.08  E-value: 3.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2574 LRSELRECKQDNERLLASLGEAQKEVLQLRSVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLE 2653
Cdd:COG3903    557 LRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAA 636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2654 ELRASLEKQFAQSSQLCVALKHEQTAKDNLQKELQIEASRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLT 2733
Cdd:COG3903    637 AAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAA 716

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2734 EQLSRGPRESPAHHALLRkLKEEKSRAAELQARLEQVQRQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQ 2813
Cdd:COG3903    717 AAAAAAAAAALLAAAAAA-ALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAA 795

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2814 AGLEPLQAGLAAQEGRKDARRADVGPGRADAEMRPTGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAER 2893
Cdd:COG3903    796 AAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAA 875

                          330       340
                   ....*....|....*....|..
gi 1953366521 2894 LQEERLGLERVRQQLLCAAGLL 2915
Cdd:COG3903    876 AAAAAAAALLAAAAAAAAAAAA 897
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2744-2903 3.57e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 3.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2744 PAHHALLRKLKEEKSRAAELQARLEQVQRQQEADVQKRRAELERE-------KEVRAAQAREPGRCLRREGHASQQQAG- 2815
Cdd:COG4913    258 RELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAelarleaELERLEARLDALREELDELEAQIRGNGg 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2816 --LEPLQAGLAAQEGRKDARRADVGpgRADAEMRPTGAKEKLRELELQRQRDEHK---------IRQLQRTVQALEAKEE 2884
Cdd:COG4913    338 drLEQLEREIERLERELEERERRRA--RLEALLAALGLPLPASAEEFAALRAEAAallealeeeLEALEEALAEAEAALR 415

                          170
                   ....*....|....*....
gi 1953366521 2885 AAQRpEAERLQEERLGLER 2903
Cdd:COG4913    416 DLRR-ELRELEAEIASLER 433
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1396-1721 3.82e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.96  E-value: 3.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1396 EELSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEEQLRQaarprphgprvsdeeqLDEEVELLQEKLR 1475
Cdd:pfam07888   41 QERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQ----------------SREKHEELEEKYK 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1476 EKSDGFNELVIKKELADRQVMIQEEEIRRLEETNASCRREAAQLREELERQRD-AMKALQQDKEALQEKQmsnlllvsTL 1554
Cdd:pfam07888  105 ELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKErAKKAGAQRKEEEAERK--------QL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1555 QSKLDEGRcpvppADSCPEGPEVQleAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNL---------ELDAQS 1625
Cdd:pfam07888  177 QAKLQQTE-----EELRSLSKEFQ--ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEAlleelrslqERLNAS 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1626 SRAAVSVRELQEENASLKAFLQNKEKEIMCVSEQLEAQLAGMgSGALREvtyDRSSEIEELRSIIENLRENQQRLQKEKA 1705
Cdd:pfam07888  250 ERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADA-SLALRE---GRARWAQERETLQQSAEADKDRIEKLSA 325

                          330
                   ....*....|....*.
gi 1953366521 1706 EemeqLHEVIERLQEE 1721
Cdd:pfam07888  326 E----LQRLEERLQEE 337
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
217-416 4.19e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  217 ETAKLKEKLQSEMERNARAVESLKRDwESERGLCLENLRRELSAKHRSELENLQDQFKRELSEQKAELEKIFQAKNQAEC 296
Cdd:COG4913    245 EDAREQIELLEPIRELAERYAAARER-LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALRE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  297 ALRTLEAQHEEALRQLREDLQSERCQYVQDLELRLRD-QEVEKQ-----LELESLRASYAELKAQSQEEIRRLWSQLESP 370
Cdd:COG4913    324 ELDELEAQIRGNGGDRLEQLEREIERLERELEERERRrARLEALlaalgLPLPASAEEFAALRAEAAALLEALEEELEAL 403

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1953366521  371 RPDRQDASAR-TPHGEELEQRERECGVQQQRRGR--------RAEQESELGQSPE 416
Cdd:COG4913    404 EEALAEAEAAlRDLRRELRELEAEIASLERRKSNiparllalRDALAEALGLDEA 458
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 146-879 4.20e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 4.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  146 SLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQeLALLRSRQQQELELAREQHAREQEEMRLRCSQETAKLKEK- 224
Cdd:pfam15921  209 SMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQ-LEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKa 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  225 ---------LQSEME---RNARAVESLKRDWESERGLCLENLRRELSAKHRS---ELENLQDQF---KRELSEQKAELEK 286
Cdd:pfam15921  288 ssarsqansIQSQLEiiqEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMyedKIEELEKQLvlaNSELTEARTERDQ 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  287 IFQAKNQAECALRTLEAQHEEALRQLreDLQSERCQYVQDLEL-------RLRDQEVEKQLELESLRASYAELKAQSQEE 359
Cdd:pfam15921  368 FSQESGNLDDQLQKLLADLHKREKEL--SLEKEQNKRLWDRDTgnsitidHLRRELDDRNMEVQRLEALLKAMKSECQGQ 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  360 IRRLWSQLESPRPDRQDASARTPHGEELEQREREcgVQQQRRGRRAEQESelgqspegaAERGREDpvlLEQRLQDatEE 439
Cdd:pfam15921  446 MERQMAAIQGKNESLEKVSSLTAQLESTKEMLRK--VVEELTAKKMTLES---------SERTVSD---LTASLQE--KE 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  440 PSLESGGIGPSSMRegerreQRVGPSLQP-ELAENHRCHLTAWTSSLEA--QQQAGLVETQESEGEQREGLSEGPGQELT 516
Cdd:pfam15921  510 RAIEATNAEITKLR------SRVDLKLQElQHLKNEGDHLRNVQTECEAlkLQMAEKDKVIEILRQQIENMTQLVGQHGR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  517 QVPVpcAQGTALKVDTEVVARGLGLEAEH--RLKLLLLQTELKEEMDVLKLENRNLHEKLQHEVCLKEDLERVKHSL--- 591
Cdd:pfam15921  584 TAGA--MQVEKAQLEKEINDRRLELQEFKilKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLlne 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  592 VEDHREELKKANERLQLVKQELKDKEAEWKVASEDLK---RKAEEELTLMLHDLKEQAEAEKQSVINKFELREikmrqlq 668
Cdd:pfam15921  662 VKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmqlKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK------- 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  669 dqqaaQILDLEGSLVEQQGRLRQLEHGLEAEECPRcgHCGQEPAGRVapADQDWELATRRLREDCALQLMQAQSRFLKER 748
Cdd:pfam15921  735 -----QITAKRGQIDALQSKIQFLEEAMTNANKEK--HFLKEEKNKL--SQELSTVATEKNKMAGELEVLRSQERRLKEK 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  749 keltekfTAEQDALLQEAQEKHACDMRLLQERHQQHVlsltaQLEARRRAEVEELKASVESERWALAearvAELQTEHAA 828
Cdd:pfam15921  806 -------VANMEVALDKASLQFAECQDIIQRQEQESV-----RLKLQHTLDVKELQGPGYTSNSSMK----PRLLQPASF 869

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1953366521  829 AISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQEKEA 879
Cdd:pfam15921  870 TRTHSNVPSSQSTASFLSHHSRKTNALKEDPTRDLKQLLQELRSVINEEPT 920
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1217-1604 5.48e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 5.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1217 RQLEEARQIHSRFEKefsCKNEETAQVVRKQQQLLERLEEenaARTRLMLELHQAQGIIEGFKEEKASLQEAL------- 1289
Cdd:PRK03918   362 ELYEEAKAKKEELER---LKKRLTGLTPEKLEKELEELEK---AKEEIEEEISKITARIGELKKEIKELKKAIeelkkak 435

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1290 -----CRQETAEHGLAEELEGLRQQLQQAAQQQAELKEENSALwsqkeasaaeaeareAALRREVECLTQEQSEARKQSE 1364
Cdd:PRK03918   436 gkcpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKL---------------RKELRELEKVLKKESELIKLKE 500

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1365 kdraaLLSQMKvfeaELEEQLSRH--EACAKQAEELSALRQQMAALDKHLRSQRQFMdEQAVEREHEREEFQREIQRLEE 1442
Cdd:PRK03918   501 -----LAEQLK----ELEEKLKKYnlEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDELEE 570

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1443 QLRQAARpRPHGPRVSDEEQLDEEVELLQEKLREksdgFNELV-IKKELADRqvmiqEEEIRRLEETNASCRREAAQLRE 1521
Cdd:PRK03918   571 ELAELLK-ELEELGFESVEELEERLKELEPFYNE----YLELKdAEKELERE-----EKELKKLEEELDKAFEELAETEK 640

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1522 ELERQRDAMKALQQDKEALQEKQMSNLLLvsTLQSKLdegrcpvppadscpEGPEVQLEAVQRALQQRESEVLDLKEQLG 1601
Cdd:PRK03918   641 RLEELRKELEELEKKYSEEEYEELREEYL--ELSREL--------------AGLRAELEELEKRREEIKKTLEKLKEELE 704


                   ...
gi 1953366521 1602 KMK 1604
Cdd:PRK03918   705 ERE 707
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 2616-2897 5.94e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 5.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2616 ALQELESERGKERALQSRL---EEAQLQHLQREGQSSKTLEELRASLEKQFA-QSSQLCVALKHEQTAKDNLQKELQIEA 2691
Cdd:pfam17380  283 AVSERQQQEKFEKMEQERLrqeKEEKAREVERRRKLEEAEKARQAEMDRQAAiYAEQERMAMERERELERIRQEERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2692 SRC-EALLAQERGQLSELQRsLEAEKGRSLELA----AALRHERLLTEQLSRGPRESP------------AHHALLRKLK 2754
Cdd:pfam17380  363 ERIrQEEIAMEISRMRELER-LQMERQQKNERVrqelEAARKVKILEEERQRKIQQQKvemeqiraeqeeARQREVRRLE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2755 EEKSRAAEL-----QARLEQVQ--RQQEADVQKRRAELEREKEVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAAQE 2827
Cdd:pfam17380  442 EERAREMERvrleeQERQQQVErlRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKE 521

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366521 2828 grKDARRADVgpgrADAEMRPTGAKEKLRELEL-QRQRDEHKIRQLQRTVQALEA----KEEAAQRPEAERLQEE 2897
Cdd:pfam17380  522 --MEERQKAI----YEEERRREAEEERRKQQEMeERRRIQEQMRKATEERSRLEAmereREMMRQIVESEKARAE 590
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 192-502 6.52e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 6.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  192 QQQELELAREQHAREQEEMRLRCSQETAKlkeklQSEMERNArAVESLKRDWESERGLCLENLRRElsaKHRSELENL-Q 270
Cdd:pfam17380  297 EQERLRQEKEEKAREVERRRKLEEAEKAR-----QAEMDRQA-AIYAEQERMAMERERELERIRQE---ERKRELERIrQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  271 DQFKRELSEQKaELEKIFQAKNQAECALRT-LEAQHEEALrqLREDLQSERCQYVQDLELRLRDQEVEKQLELESLRASY 349
Cdd:pfam17380  368 EEIAMEISRMR-ELERLQMERQQKNERVRQeLEAARKVKI--LEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEER 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  350 A-ELKAQSQEEIRRlWSQLESPrpdRQDASARTPHGEELEQRERECGVQQQRRGRRAEQESELGQSPEGAAERGREdpvL 428
Cdd:pfam17380  445 ArEMERVRLEEQER-QQQVERL---RQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRK---L 517

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953366521  429 LEQRLQD-ATEEPSLESGGIGPSSMREGERREQRVGPSLQPELAENHRCHLTAWTSSLEAQQQAGLVETQESEGE 502
Cdd:pfam17380  518 LEKEMEErQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 593-843 6.52e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 6.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  593 EDHREELKKANERLQLVKQELKDKEAEWKVASEDLKRkaeeeltlmlhdlKEQAEAEKQSVINKFELREIKMRQLQDQQA 672
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA-------------LERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  673 AQILDLEGSLVEQQGRLRQLEHGLEAEecprcghcGQEPAGRVAPADQDWELATRRlredcaLQLMQAQSRFLKERKELT 752
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRL--------GRQPPLALLLSPEDFLDAVRR------LQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  753 EKFTAEQDALLQEAQEKHACDMRLLQERHQQHvlSLTAQLEARRRAEVEELKASVESERWALAE--ARVAELQTEHAAAI 830
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEER--AALEALKAERQKLLARLEKELAELAAELAElqQEAEELEALIARLE 233

                          250
                   ....*....|...
gi 1953366521  831 SALEARHSALLGS 843
Cdd:COG4942    234 AEAAAAAERTPAA 246
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1421-1673 7.17e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 7.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1421 EQAVEREHEREEFQREIQRLEEQLRQAARprphgprvsDEEQLDEEVELLQEKLREKSDGFNELvikkelaDRQVMIQEE 1500
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKK---------EEKALLKQLAALERRIAALARRIRAL-------EQELAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1501 EIRRLEETNASCRREAAQLREELERQ---------RDAMKALQQDKEALQEKQMSNLL---------LVSTLQSKLDEgr 1562
Cdd:COG4942     84 ELAELEKEIAELRAELEAQKEELAELlralyrlgrQPPLALLLSPEDFLDAVRRLQYLkylaparreQAEELRADLAE-- 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1563 cpvppadscpegpevqLEAVQRALQQRESEVLDLKEQLGKMKDDLVSKSDEVLHLNLELDAQSSRAAVSVRELQEENASL 1642
Cdd:COG4942    162 ----------------LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225

                          250       260       270
                   ....*....|....*....|....*....|.
gi 1953366521 1643 KAFLQNKEKEIMCVSEQLEAQLAGMGSGALR 1673
Cdd:COG4942    226 EALIARLEAEAAAAAERTPAAGFAALKGKLP 256
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2455-3007 7.30e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 7.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2455 SLLERLEKVVQEQEKSLEHLRA---SDRSSLLSEIQALRAQLRmthlQNQEKLQQLCAALTSAEARgsrqEHQLRRQVEL 2531
Cdd:TIGR02169  304 ASLERSIAEKERELEDAEERLAkleAEIDKLLAEIEELEREIE----EERKRRDKLTEEYAELKEE----LEDLRAELEE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2532 LAYKVEQEKRIASDVQKTLTEEQEKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLR-------- 2603
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAleikkqew 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2604 ---------SVLDSKESNLRAALQELESERGKERALQSRLEEAQLQHLQREGQSSKTLEELRASLEKQFAQSSQLCVALK 2674
Cdd:TIGR02169  456 kleqlaadlSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE 535

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2675 HEQTA--------KDNLQKELQIEASRCEALLAQERG-----------QLSELQRSLEAEKG------------------ 2717
Cdd:TIGR02169  536 RYATAievaagnrLNNVVVEDDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGvigfavdlvefdpkyepa 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2718 -----------RSLELAAALRHE-RLLT---EQLSRGPRESPAHHALLRKL---KEEKSRAAELQARLEQVQRqQEADVQ 2779
Cdd:TIGR02169  616 fkyvfgdtlvvEDIEAARRLMGKyRMVTlegELFEKSGAMTGGSRAPRGGIlfsRSEPAELQRLRERLEGLKR-ELSSLQ 694

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2780 KRRAELEREKEVRAAQAREPGRCLRR--------EGHASQQQAGLEPLQAGLAAQEGRKDARRADVGPGRAD-AEMRPTG 2850
Cdd:TIGR02169  695 SELRRIENRLDELSQELSDASRKIGEiekeieqlEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARiEELEEDL 774

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2851 AKEKLRELELQRQRDEHKIRQLQRTVQALEAK----EEAAQRPEAE--RLQEERLGLERVRQQLLCAAGLLTSFIsrtvd 2924
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRIPEIQAELSKLEEEvsriEARLREIEQKlnRLTLEKEYLEKEIQELQEQRIDLKEQI----- 849

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2925 rtisdwtSSNEKAVTSLLHTLEELKSELstpsSSQKKMTAELQTQLVDvLLKDNDSLTKALRTVTQEKAELCRAVSQLEK 3004
Cdd:TIGR02169  850 -------KSIEKEIENLNGKKEELEEEL----EELEAALRDLESRLGD-LKKERDELEAQLRELERKIEELEAQIEKKRK 917


                   ...
gi 1953366521 3005 SLK 3007
Cdd:TIGR02169  918 RLS 920
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2610-2908 7.42e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2610 ESNLRAALQELESERGKERALQSRLEEA--QLQHLQREGQSSKTLEELRASLEkqfaqssqlcvalKHEQTAKDNLQKEL 2687
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKrqQLERLRREREKAERYQALLKEKR-------------EYEGYELLKEKEAL 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2688 QIEASRCEALLAQERGQLSELQRSLEAekgRSLELAAALRHERLLTEQLSRGPRESPAhhALLRKLKEEKSRAAELQARL 2767
Cdd:TIGR02169  236 ERQKEAIERQLASLEEELEKLTEEISE---LEKRLEEIEQLLEELNKKIKDLGEEEQL--RVKEKIGELEAEIASLERSI 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2768 EQVQRQQEaDVQKRRAELEREKEVRAAQAREPGRCLRreghasQQQAGLEPLQAGLAAQEGRKDARRADVGPGRAD-AEM 2846
Cdd:TIGR02169  311 AEKERELE-DAEERLAKLEAEIDKLLAEIEELEREIE------EERKRRDKLTEEYAELKEELEDLRAELEEVDKEfAET 383

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953366521 2847 RPTGAKEKLRELELQRQRDEHK--IRQLQRTVQALEAKEEAAqRPEAERLQEERLGLERVRQQL 2908
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKreLDRLQEELQRLSEELADL-NAAIAGIEAKINELEEEKEDK 446
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1360-1508 7.86e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 7.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1360 RKQSEKDRAALLSQMKVFEAELEEQLSRHEacakqaEELSALRQQMAALDKHLRsqrqfmdeqavEREHEREEFQREIQR 1439
Cdd:COG2433    383 EELIEKELPEEEPEAEREKEHEERELTEEE------EEIRRLEEQVERLEAEVE-----------ELEAELEEKDERIER 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1440 LEEQLRQAARPRPHGPRVSDE-EQLDEEVELLQEKLREKSDGFNEL---------VIKKELADRQVMIQE------EEIR 1503
Cdd:COG2433    446 LERELSEARSEERREIRKDREiSRLDREIERLERELEEERERIEELkrklerlkeLWKLEHSGELVPVKVvekftkEAIR 525


                   ....*
gi 1953366521 1504 RLEET 1508
Cdd:COG2433    526 RLEEE 530
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 151-429 8.38e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 8.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  151 HTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQhareqeEMRLRCSQETA-------KLKE 223
Cdd:COG3096    409 QTRAIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLEL------EQKLSVADAARrqfekayELVC 482

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  224 KLQSEMERNA---RAVESLkRDWESERGLC--LENLRRELSakhrsELENLQDQfKRELSEQKAELEKIFQAKNQAECAL 298
Cdd:COG3096    483 KIAGEVERSQawqTARELL-RRYRSQQALAqrLQQLRAQLA-----ELEQRLRQ-QQNAERLLEEFCQRIGQQLDAAEEL 555

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521  299 RTLEAQHEEALRQLrEDLQSErcqyvqdlelrLRDQEVEKQLELESLRASYAELKAQ------SQEEIRRLWSQLESPRP 372
Cdd:COG3096    556 EELLAELEAQLEEL-EEQAAE-----------AVEQRSELRQQLEQLRARIKELAARapawlaAQDALERLREQSGEALA 623

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1953366521  373 DRQDASArtpHGEELEQREREcgVQQQRRGRRAEQESELGQSPEGAAERGREDPVLL 429
Cdd:COG3096    624 DSQEVTA---AMQQLLERERE--ATVERDELAARKQALESQIERLSQPGGAEDPRLL 675
PRK12704 PRK12704
phosphodiesterase; Provisional
 1378-1555 9.79e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 9.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1378 EAELEEQLSRHEACAKQAEELSALRQQMaaldkhlrsqrqfmdeqaverEHEREEFQREIQRLEEQLRQAarprphgprv 1457
Cdd:PRK12704    46 EAKKEAEAIKKEALLEAKEEIHKLRNEF---------------------EKELRERRNELQKLEKRLLQK---------- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 1458 sdEEQLDEEVELLQEKLREKSDGFNELVIKKELADRQVM----IQEEEIRRLEETNASCRREA-AQLREELERQ--RDAM 1530
Cdd:PRK12704    95 --EENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEeleeLIEEQLQELERISGLTAEEAkEILLEKVEEEarHEAA 172

                          170       180
                   ....*....|....*....|....*..
gi 1953366521 1531 KALQQ-DKEALQE-KQMSNLLLVSTLQ 1555
Cdd:PRK12704   173 VLIKEiEEEAKEEaDKKAKEILAQAIQ 199
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2458-2909 9.99e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 9.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2458 ERLEKVVQEQEKSLEHLrASDRSSLLSEIQALRAQLRMthLQNQEKLQQlcaaltsaeARGSRQEHQLRRQVELLAYKVE 2537
Cdd:pfam15921  267 DRIEQLISEHEVEITGL-TEKASSARSQANSIQSQLEI--IQEQARNQN---------SMYMRQLSDLESTVSQLRSELR 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2538 QEKRIASDvqktlteeqeKASSVRKLLVVEQTVVRDLRSELRECKQDNERllaslgeaqkevlqlrsvLDSKESNLRAAL 2617
Cdd:pfam15921  335 EAKRMYED----------KIEELEKQLVLANSELTEARTERDQFSQESGN------------------LDDQLQKLLADL 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2618 QELESERGKERALQSRLEEaqlqhlqREGQSSKTLEELRASLEKQFAQSSQLCVALKHEQTAKDNlQKELQIEA------ 2691
Cdd:pfam15921  387 HKREKELSLEKEQNKRLWD-------RDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQG-QMERQMAAiqgkne 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2692 --SRCEALLAQERGQLSELQRSLEAEKGRSLELAAALRHERLLTEQLSRGPRESPAHHALLRKLKeeksraAELQARLEQ 2769
Cdd:pfam15921  459 slEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLR------SRVDLKLQE 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953366521 2770 VQRQQEADVQKRRAELEREK-EVRAAQAREPGRCLRREGHASQQQAGLEPLQAGLAAQEgrkdarradvgpgRADAEMRP 2848
Cdd:pfam15921  533 LQHLKNEGDHLRNVQTECEAlKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVE-------------KAQLEKEI 599

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953366521 2849 TGAKEKLRELELQRQRDEHKIRQLQRTVQALEAKEEAAQRPEAERLQEERlGLERVRQQLL 2909
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVK-DIKQERDQLL 659
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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