NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1953340826|ref|XP_038290683|]
View 

transcription factor SPT20 homolog isoform X1 [Canis lupus familiaris]

Protein Classification

SPT20 family protein( domain architecture ID 10572640)

SPT20 family protein similar to transcription factor SPT20 that may recruit TATA binding protein (TBP) and possibly other basal factors to bind to the TATA box

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Spt20 pfam12090
Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. ...
77-214 7.42e-23

Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains.


:

Pssm-ID: 463459 [Multi-domain]  Cd Length: 176  Bit Score: 96.33  E-value: 7.42e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953340826  77 LVVNLYPgnEGYSLMlrgkngSDSETIRLPYEE--GELLEYLDAEELPPILVDLLEKSQVnIFHCGCVIAEIRDYR---- 150
Cdd:pfam12090   7 LILHLYP--KHFRIN------NSTDEGIFPYNSemRKFLEHIERGTIPPEILELLRDFNI-KFYDGCLIVQIIDHRntpq 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953340826 151 ---------QSSNMKSPGYQSR-------------HILLRPTMQTLICDVhSITSDN--HKWTQEDKLLLESQLILATAE 206
Cdd:pfam12090  78 qspkttnpqQNQQQPAPGNNNSskkkkttvkprvyRTLLRPTPQSLYADL-TSLSDTpkMRLSDEDLLELESEILLATNP 156

                  ....*...
gi 1953340826 207 PLCLDPSI 214
Cdd:pfam12090 157 PLCLDPSP 164
 
Name Accession Description Interval E-value
Spt20 pfam12090
Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. ...
77-214 7.42e-23

Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains.


Pssm-ID: 463459 [Multi-domain]  Cd Length: 176  Bit Score: 96.33  E-value: 7.42e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953340826  77 LVVNLYPgnEGYSLMlrgkngSDSETIRLPYEE--GELLEYLDAEELPPILVDLLEKSQVnIFHCGCVIAEIRDYR---- 150
Cdd:pfam12090   7 LILHLYP--KHFRIN------NSTDEGIFPYNSemRKFLEHIERGTIPPEILELLRDFNI-KFYDGCLIVQIIDHRntpq 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953340826 151 ---------QSSNMKSPGYQSR-------------HILLRPTMQTLICDVhSITSDN--HKWTQEDKLLLESQLILATAE 206
Cdd:pfam12090  78 qspkttnpqQNQQQPAPGNNNSskkkkttvkprvyRTLLRPTPQSLYADL-TSLSDTpkMRLSDEDLLELESEILLATNP 156

                  ....*...
gi 1953340826 207 PLCLDPSI 214
Cdd:pfam12090 157 PLCLDPSP 164
 
Name Accession Description Interval E-value
Spt20 pfam12090
Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. ...
77-214 7.42e-23

Spt20 family; This presumed domain is found in the Spt20 proteins from both human and yeast. The Spt20 protein is part of the SAGA complex which is a large complex mediating histone deacetylation. Yeast Spt20 has been shown to play a role in structural integrity of the SAGA complex as as no intact SAGA could be purified in spt20 deletion strains.


Pssm-ID: 463459 [Multi-domain]  Cd Length: 176  Bit Score: 96.33  E-value: 7.42e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953340826  77 LVVNLYPgnEGYSLMlrgkngSDSETIRLPYEE--GELLEYLDAEELPPILVDLLEKSQVnIFHCGCVIAEIRDYR---- 150
Cdd:pfam12090   7 LILHLYP--KHFRIN------NSTDEGIFPYNSemRKFLEHIERGTIPPEILELLRDFNI-KFYDGCLIVQIIDHRntpq 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953340826 151 ---------QSSNMKSPGYQSR-------------HILLRPTMQTLICDVhSITSDN--HKWTQEDKLLLESQLILATAE 206
Cdd:pfam12090  78 qspkttnpqQNQQQPAPGNNNSskkkkttvkprvyRTLLRPTPQSLYADL-TSLSDTpkMRLSDEDLLELESEILLATNP 156

                  ....*...
gi 1953340826 207 PLCLDPSI 214
Cdd:pfam12090 157 PLCLDPSP 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH