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Conserved domains on  [gi|1938261357|ref|XP_037837358|]
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heparan sulfate glucosamine 3-O-sulfotransferase 5 [Kryptolebias marmoratus]

Protein Classification

sulfotransferase family protein( domain architecture ID 229543)

sulfotransferase family protein may utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to its substrate(s)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sulfotransfer_1 super family cl21551
Sulfotransferase domain;
89-329 2.64e-28

Sulfotransferase domain;


The actual alignment was detected with superfamily member pfam00685:

Pssm-ID: 473908 [Multi-domain]  Cd Length: 253  Bit Score: 110.51  E-value: 2.64e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357  89 LPQAIIIGVRKGGTRALLEMLNLHPAV--IKASQEIHFFDNdKNYAWGINWYREKMPFSF---PHQITIEKSPAYFVTEE 163
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGDTYFDVaegPVRLNALPSPRIIKTHL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357 164 VPERIFK--MNSSVKLLIIVREPTTRAVSDYTQVLEGKERKNKTYHKFEhlavdastcEVNTKYKAVRTSIYAKHLERWL 241
Cdd:pfam00685  80 PLHLLPKslWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEF---------VEDFLNGKVNCGSYFDHVKGWW 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357 242 KYFPVEQFHVVDGDRLITDPVPELQLVERFLNLPSKISQ-----YNLYFNVTRGFYCLRFNFGSN-------KCLAGSKg 309
Cdd:pfam00685 151 KLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGNPCLNYSKLPKevspffrKGLVGDW- 229

                         250       260
                  ....*....|....*....|
gi 1938261357 310 RTHPDVDQSvvMKLQKFFHP 329
Cdd:pfam00685 230 KNYFTPEQA--EKFDEIYQE 247
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
89-329 2.64e-28

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 110.51  E-value: 2.64e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357  89 LPQAIIIGVRKGGTRALLEMLNLHPAV--IKASQEIHFFDNdKNYAWGINWYREKMPFSF---PHQITIEKSPAYFVTEE 163
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGDTYFDVaegPVRLNALPSPRIIKTHL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357 164 VPERIFK--MNSSVKLLIIVREPTTRAVSDYTQVLEGKERKNKTYHKFEhlavdastcEVNTKYKAVRTSIYAKHLERWL 241
Cdd:pfam00685  80 PLHLLPKslWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEF---------VEDFLNGKVNCGSYFDHVKGWW 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357 242 KYFPVEQFHVVDGDRLITDPVPELQLVERFLNLPSKISQ-----YNLYFNVTRGFYCLRFNFGSN-------KCLAGSKg 309
Cdd:pfam00685 151 KLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGNPCLNYSKLPKevspffrKGLVGDW- 229

                         250       260
                  ....*....|....*....|
gi 1938261357 310 RTHPDVDQSvvMKLQKFFHP 329
Cdd:pfam00685 230 KNYFTPEQA--EKFDEIYQE 247
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
89-329 2.64e-28

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 110.51  E-value: 2.64e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357  89 LPQAIIIGVRKGGTRALLEMLNLHPAV--IKASQEIHFFDNdKNYAWGINWYREKMPFSF---PHQITIEKSPAYFVTEE 163
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGDTYFDVaegPVRLNALPSPRIIKTHL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357 164 VPERIFK--MNSSVKLLIIVREPTTRAVSDYTQVLEGKERKNKTYHKFEhlavdastcEVNTKYKAVRTSIYAKHLERWL 241
Cdd:pfam00685  80 PLHLLPKslWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEF---------VEDFLNGKVNCGSYFDHVKGWW 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357 242 KYFPVEQFHVVDGDRLITDPVPELQLVERFLNLPSKISQ-----YNLYFNVTRGFYCLRFNFGSN-------KCLAGSKg 309
Cdd:pfam00685 151 KLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGNPCLNYSKLPKevspffrKGLVGDW- 229

                         250       260
                  ....*....|....*....|
gi 1938261357 310 RTHPDVDQSvvMKLQKFFHP 329
Cdd:pfam00685 230 KNYFTPEQA--EKFDEIYQE 247
Sulfotransfer_3 pfam13469
Sulfotransferase family;
93-275 5.37e-11

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 60.77  E-value: 5.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357  93 IIIGVRKGGTRALLEMLNLHPAVikASQEIHFFDNDKNYAWGINWYREK---MPFSFPHQITIEKSPAYFVTeevPERIF 169
Cdd:pfam13469   2 FIVGLPRSGTTLLHRLLAAHPDV--RPPEETWFVIPRILALLQAWGKSLealARVPSYARWLCDKSPSHLFH---LDLLL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938261357 170 KMNSSVKLLIIVREPTTRAVSDYTQvLEGKERKNKTYHKFEHLAVDASTcevntkykavrtsiYAKHLERWL---KYFPV 246
Cdd:pfam13469  77 KAFPDAKFIHLHRDPVDTVISSYCS-LFGFTLSSYSTAFLRDIGLALAR--------------WSRAYERLMaarARVPP 141

                         170       180
                  ....*....|....*....|....*....
gi 1938261357 247 EQFHVVDGDRLITDPVPELQLVERFLNLP 275
Cdd:pfam13469 142 GRFLDVRYEDLVADPEGTLRRILEFLGLP 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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