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Conserved domains on  [gi|1907126631|ref|XP_036016715|]
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serine/arginine repetitive matrix protein 2 isoform X5 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
39-102 8.09e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


:

Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 116.65  E-value: 8.09e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907126631   39 EEELRHLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375      1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
309-686 6.45e-10

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 65.19  E-value: 6.45e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  309 PSVEPGATNIQQPSSPAPSTKQSSSPyeDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEP 388
Cdd:PHA03307    75 PGTEAPANESRSTPTWSLSTLAPASP--AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP 152
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  389 VNPSSEASPTRGCSPPKSPEKPPQSTSSES--CPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAK 466
Cdd:PHA03307   153 PAAGASPAAVASDAASSRQAALPLSSPEETarAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDA 232
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  467 RDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGwSRSRNTQ 546
Cdd:PHA03307   233 GASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPG-SGPAPSS 311
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  547 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPARRRSRSRTPARRGRSRSRTPARRRSRTRS 626
Cdd:PHA03307   312 PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  627 pvrrrsrsrsqarrsgrsrsrtPARRSGRSRSRTPARRGRSRSRTPARRSARSRSRTPAR 686
Cdd:PHA03307   392 ----------------------AAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR 429
PHA03247 super family cl33720
large tegument protein UL36; Provisional
1982-2466 1.06e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.57  E-value: 1.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 1982 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPraargkrsltrsPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2061
Cdd:PHA03247  2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPD------------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR 2663
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2062 sSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSArtpmsvlqqtgGSMMDGPGPRIPDHPRSsvpenhaqsrialalTAIS 2141
Cdd:PHA03247  2664 -PRRARRLGRAAQASSPPQRPRRRAARPTVGSL-----------TSLADPPPPPPTPEPAP---------------HALV 2716
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2142 LGTARPPPSMSAAGLAARMSQVPAPVPLMslrTAPAANLASRIPAASAAAMNLASARTSAIPASvnladsrTPAAAAAMN 2221
Cdd:PHA03247  2717 SATPLPPGPAAARQASPALPAAPAPPAVP---AGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------GPPRRLTRP 2786
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2222 LASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAAlsltgSGTPPTAANYPSSSRTPQAPTPANLVVGprsaHGTA 2301
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-----GPLPPPTSAQPTAPPPPPGPPPPSLPLG----GSVA 2857
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2302 PVNIAGSRTPAGLAPTNLSSSRMAPALSganLTSPRVPLSAydrvsgRTSPLMLDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PHA03247  2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---LARPAVSRST------ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2382 PASRM-VQASSQSLLPPAQDRPRSPVPS-AFSDQSRSVVQTTPVAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGIS--- 2456
Cdd:PHA03247  2929 PQPPPpPPPRPQPPLAPTTDPAGAGEPSgAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSswa 3008
                          490
                   ....*....|....*
gi 1907126631 2457 -----HAEGGEPPAS 2466
Cdd:PHA03247  3009 sslalHEETDPPPVS 3023
 
Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
39-102 8.09e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 116.65  E-value: 8.09e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907126631   39 EEELRHLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375      1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
309-686 6.45e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 65.19  E-value: 6.45e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  309 PSVEPGATNIQQPSSPAPSTKQSSSPyeDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEP 388
Cdd:PHA03307    75 PGTEAPANESRSTPTWSLSTLAPASP--AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP 152
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  389 VNPSSEASPTRGCSPPKSPEKPPQSTSSES--CPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAK 466
Cdd:PHA03307   153 PAAGASPAAVASDAASSRQAALPLSSPEETarAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDA 232
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  467 RDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGwSRSRNTQ 546
Cdd:PHA03307   233 GASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPG-SGPAPSS 311
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  547 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPARRRSRSRTPARRGRSRSRTPARRRSRTRS 626
Cdd:PHA03307   312 PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  627 pvrrrsrsrsqarrsgrsrsrtPARRSGRSRSRTPARRGRSRSRTPARRSARSRSRTPAR 686
Cdd:PHA03307   392 ----------------------AAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR 429
PHA03247 PHA03247
large tegument protein UL36; Provisional
1982-2466 1.06e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.57  E-value: 1.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 1982 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPraargkrsltrsPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2061
Cdd:PHA03247  2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPD------------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR 2663
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2062 sSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSArtpmsvlqqtgGSMMDGPGPRIPDHPRSsvpenhaqsrialalTAIS 2141
Cdd:PHA03247  2664 -PRRARRLGRAAQASSPPQRPRRRAARPTVGSL-----------TSLADPPPPPPTPEPAP---------------HALV 2716
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2142 LGTARPPPSMSAAGLAARMSQVPAPVPLMslrTAPAANLASRIPAASAAAMNLASARTSAIPASvnladsrTPAAAAAMN 2221
Cdd:PHA03247  2717 SATPLPPGPAAARQASPALPAAPAPPAVP---AGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------GPPRRLTRP 2786
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2222 LASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAAlsltgSGTPPTAANYPSSSRTPQAPTPANLVVGprsaHGTA 2301
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-----GPLPPPTSAQPTAPPPPPGPPPPSLPLG----GSVA 2857
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2302 PVNIAGSRTPAGLAPTNLSSSRMAPALSganLTSPRVPLSAydrvsgRTSPLMLDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PHA03247  2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---LARPAVSRST------ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2382 PASRM-VQASSQSLLPPAQDRPRSPVPS-AFSDQSRSVVQTTPVAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGIS--- 2456
Cdd:PHA03247  2929 PQPPPpPPPRPQPPLAPTTDPAGAGEPSgAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSswa 3008
                          490
                   ....*....|....*
gi 1907126631 2457 -----HAEGGEPPAS 2466
Cdd:PHA03247  3009 sslalHEETDPPPVS 3023
cwf21 pfam08312
cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a ...
58-101 1.35e-07

cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe. The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevent Prp8 from binding. The structure of this domain has recently been solved which shows this domain to be composed of two alpha helices.


Pssm-ID: 462421 [Multi-domain]  Cd Length: 44  Bit Score: 49.73  E-value: 1.35e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1907126631   58 LDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEK 101
Cdd:pfam08312    1 LEHERKREIEVKVLELRDELEEQGLSEEEIEEKVDELRKKLLAE 44
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
499-603 1.53e-05

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 50.28  E-value: 1.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  499 KRGHSRSRSPQWRRSRSAQRWgKSRSPQRRGRSRSpqRPGWSRSRNtqrrgrSRSARRGRSHSRSPATRGRSRSRTPARR 578
Cdd:TIGR01642   12 SRGRDRDRSSERPRRRSRDRS-RFRDRHRRSRERS--YREDSRPRD------RRRYDSRSPRSLRYSSVRRSRDRPRRRS 82
                           90       100
                   ....*....|....*....|....*
gi 1907126631  579 GRSRSRTPARRRSRSRTPARRRSRS 603
Cdd:TIGR01642   83 RSVRSIEQHRRRLRDRSPSNQWRKD 107
RSRP pfam17069
Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.
436-604 1.21e-03

Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.


Pssm-ID: 293674 [Multi-domain]  Cd Length: 299  Bit Score: 43.61  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  436 PESLKPTPAPGSRREISSS-PTSKNRSHGRAKRDKSHSHTPSHRAGRSRS-PATKRGRSRSRTPTKR---GHSRSRSPQW 510
Cdd:pfam17069   10 PGSPQEKKSPSTSSSGSSSrLSSRSRSRSSSRSSRSHSRSSSRFSSRSRSrPRRSRSRSRSRRRHQRkyrRYSRSYSRSR 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  511 RRSRSAQRWGKSRSPQRRGRSRSPQRpgwSRSRNTQRRGRSRSARRGRSHSRSpatrGRSRSRTPARRGRSRSRTpaRRR 590
Cdd:pfam17069   90 SRSRRRRYYRRSRYRYSRRYYRSPSR---SRSRSRSRSRGRSYYAIWRGSRYY----GFGRTVYPERSPRWRSRS--RTR 160
                          170
                   ....*....|....
gi 1907126631  591 SRSRTPARRRSRSR 604
Cdd:pfam17069  161 SRSRTPFRLSEKER 174
 
Name Accession Description Interval E-value
cwf21_SRRM2 cd21375
cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive ...
39-102 8.09e-31

cwf21 domain found in serine/arginine repetitive matrix protein 2; Serine/arginine repetitive matrix protein 2 (SRRM2) is also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803). It is required for pre-mRNA splicing as component of the spliceosome. It contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410601 [Multi-domain]  Cd Length: 64  Bit Score: 116.65  E-value: 8.09e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907126631   39 EEELRHLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21375      1 EEELRRLEAALVKKPNPDILDHERKRRVELKCLELEEMMEEQGYSEEEIQEKVATFRLMLLEKD 64
cwf21_SRRM3 cd21376
cwf21 domain found in serine/arginine repetitive matrix protein 3 and similar proteins; Serine ...
37-102 3.22e-23

cwf21 domain found in serine/arginine repetitive matrix protein 3 and similar proteins; Serine/arginine repetitive matrix protein 3 (SRRM3) may play a role in regulating breast cancer cell invasiveness. It may also be involved in RYBP-mediated breast cancer progression. SRRM3 contains a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410602 [Multi-domain]  Cd Length: 68  Bit Score: 95.19  E-value: 3.22e-23
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907126631   37 KGEEELRHLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21376      1 KSEEEIKKLDAALVKKPNREILDHERKRKVELKCMEMQELMEEQGYTEEEIRQKVSTFRQMLMEKE 66
cwf21_SRRM2-like cd21373
cwf21 domain found in serine/arginine repetitive matrix proteins, SRRM2, SRRM3 and similar ...
53-102 5.63e-17

cwf21 domain found in serine/arginine repetitive matrix proteins, SRRM2, SRRM3 and similar proteins; This subfamily includes SRRM2 and SRRM3, both of which contain a cwf21 domain at the N-terminus. SRRM2, also called 300 kDa nuclear matrix antigen, serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa, SR-related nuclear matrix protein of 300 kDa, Ser/Arg-related nuclear matrix protein of 300 kDa, splicing coactivator subunit SRm300, or Tax-responsive enhancer element-binding protein 803 (TaxREB803), is required for pre-mRNA splicing as component of the spliceosome. SRRM3 may play a role in regulating breast cancer cell invasiveness. It may be involved in RYBP-mediated breast cancer progression. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410600 [Multi-domain]  Cd Length: 50  Bit Score: 76.46  E-value: 5.63e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907126631   53 PNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21373      1 PNKEILDHERKRKIEVKCLELEDLLEEQGYTEEEIQAKVDEYRALLLEKD 50
cwf21_CWC21-like cd21372
cwf21 domain found in fungal complexed with CEF1 protein 21 (CWC21) and similar proteins; This ...
54-102 3.96e-10

cwf21 domain found in fungal complexed with CEF1 protein 21 (CWC21) and similar proteins; This subfamily includes complexed with CEF1 protein 21 (CWC21) from budding yeast, complexed with cdc5 protein 21 (CWF21) from fission yeast, as well as their orthologs, serine/arginine repetitive matrix proteins (SRRM2 and SRRM3) from vertebrates. Both CWC21 and CWF21 are pre-mRNA-splicing factors that may function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome, together with ISY1. SRRM2 is required for pre-mRNA splicing as a component of the spliceosome. SRRM3 may play a role in regulating breast cancer cell invasiveness. It may be involved in RYBP-mediated breast cancer progression. Members of this family contain a cwf21 domain at the N-terminus. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8.


Pssm-ID: 410599 [Multi-domain]  Cd Length: 49  Bit Score: 57.10  E-value: 3.96e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1907126631   54 NPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD 102
Cdd:cd21372      1 DKEILEHERKRQIELKCLELRDELEDEGLSEEEIEEKVDELREKLLKEL 49
cwf21 cd21369
cwf21 domain; The cwf21 domain is involved in mRNA splicing; it binds directly to the ...
55-101 4.05e-10

cwf21 domain; The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevents its binding to Prp8. The domain is composed of two alpha helices. Proteins containing the cwf21 domain include complexed with CEF1 protein 21 (CWC21) from budding yeast, complexed with cdc5 protein 21 (CWF21) from fission yeast, as well as their orthologs, serine/arginine repetitive matrix proteins (SRRM2 and SRRM3) from vertebrates. This domain family also includes U2-associated protein SR140 from Eumetazoa, protein RRC1, and similar proteins from plants.


Pssm-ID: 410596 [Multi-domain]  Cd Length: 48  Bit Score: 57.09  E-value: 4.05e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1907126631   55 PDILDHERKRRVELRCLELEEMMEEQG-YEEQQIQEKVATFRLMLLEK 101
Cdd:cd21369      1 MDEEKRAKKREIELKVMELRDELEEQGrKPEQQIQEKVEHYRDKLLQR 48
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
309-686 6.45e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 65.19  E-value: 6.45e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  309 PSVEPGATNIQQPSSPAPSTKQSSSPyeDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEP 388
Cdd:PHA03307    75 PGTEAPANESRSTPTWSLSTLAPASP--AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASP 152
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  389 VNPSSEASPTRGCSPPKSPEKPPQSTSSES--CPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAK 466
Cdd:PHA03307   153 PAAGASPAAVASDAASSRQAALPLSSPEETarAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDA 232
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  467 RDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGwSRSRNTQ 546
Cdd:PHA03307   233 GASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPG-SGPAPSS 311
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  547 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPARRRSRSRTPARRGRSRSRTPARRRSRTRS 626
Cdd:PHA03307   312 PRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  627 pvrrrsrsrsqarrsgrsrsrtPARRSGRSRSRTPARRGRSRSRTPARRSARSRSRTPAR 686
Cdd:PHA03307   392 ----------------------AAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR 429
PHA03247 PHA03247
large tegument protein UL36; Provisional
1982-2466 1.06e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.57  E-value: 1.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 1982 SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPraargkrsltrsPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2061
Cdd:PHA03247  2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPD------------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR 2663
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2062 sSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSArtpmsvlqqtgGSMMDGPGPRIPDHPRSsvpenhaqsrialalTAIS 2141
Cdd:PHA03247  2664 -PRRARRLGRAAQASSPPQRPRRRAARPTVGSL-----------TSLADPPPPPPTPEPAP---------------HALV 2716
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2142 LGTARPPPSMSAAGLAARMSQVPAPVPLMslrTAPAANLASRIPAASAAAMNLASARTSAIPASvnladsrTPAAAAAMN 2221
Cdd:PHA03247  2717 SATPLPPGPAAARQASPALPAAPAPPAVP---AGPATPGGPARPARPPTTAGPPAPAPPAAPAA-------GPPRRLTRP 2786
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2222 LASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAAlsltgSGTPPTAANYPSSSRTPQAPTPANLVVGprsaHGTA 2301
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-----GPLPPPTSAQPTAPPPPPGPPPPSLPLG----GSVA 2857
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2302 PVNIAGSRTPAGLAPTNLSSSRMAPALSganLTSPRVPLSAydrvsgRTSPLMLDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PHA03247  2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---LARPAVSRST------ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2382 PASRM-VQASSQSLLPPAQDRPRSPVPS-AFSDQSRSVVQTTPVAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGIS--- 2456
Cdd:PHA03247  2929 PQPPPpPPPRPQPPLAPTTDPAGAGEPSgAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSswa 3008
                          490
                   ....*....|....*
gi 1907126631 2457 -----HAEGGEPPAS 2466
Cdd:PHA03247  3009 sslalHEETDPPPVS 3023
cwf21 pfam08312
cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a ...
58-101 1.35e-07

cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe. The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevent Prp8 from binding. The structure of this domain has recently been solved which shows this domain to be composed of two alpha helices.


Pssm-ID: 462421 [Multi-domain]  Cd Length: 44  Bit Score: 49.73  E-value: 1.35e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1907126631   58 LDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEK 101
Cdd:pfam08312    1 LEHERKREIEVKVLELRDELEEQGLSEEEIEEKVDELRKKLLAE 44
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2147-2405 3.45e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 52.54  E-value: 3.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2147 PPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTSAI---PASVNLADSRTPAAAAAMNLA 2223
Cdd:PRK07003   360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAaaaAATRAEAPPAAPAPPATADRG 439
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2224 SPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPTPANLVVGPR-SAHGTAP 2302
Cdd:PRK07003   440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARaPAAASRE 519
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2303 VNIAGSRTPAGLAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTSPLMLDRARS-----RTPPSAPSQSRMTSERE 2377
Cdd:PRK07003   520 DAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPaaapaAAPKPAAPRVAVQVPTP 599
                          250       260
                   ....*....|....*....|....*...
gi 1907126631 2378 RAPSPASRMVQASSQSLLPPAQDRPRSP 2405
Cdd:PRK07003   600 RARAATGDAPPNGAARAEQAAESRGAPP 627
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
294-600 1.23e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.94  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  294 QSPPLASGHQGEGDAPSVEPGATNIQQPSSPAPSTKQSSSPYEDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHV 373
Cdd:PHA03307   150 ASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAA 229
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  374 DSPRPLAAIPSSQEPvnPSSEASPTRGCSPPKSPEKPPQSTSSESCPP-SPQPTKGSRHASSSPESLKPTPAPGSRREIS 452
Cdd:PHA03307   230 DDAGASSSDSSSSES--SGCGWGPENECPLPRPAPITLPTRIWEASGWnGPSSRPGPASSSSSPRERSPSPSPSSPGSGP 307
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  453 SSPTSKNRSHGRAKRDkSHSHTPSHRAGRSRSPATKRGRSRSRTPtkrghSRSRSPQWRRSrsaqrwgkSRSPQRRGRSR 532
Cdd:PHA03307   308 APSSPRASSSSSSSRE-SSSSSTSSSSESSRGAAVSPGPSPSRSP-----SPSRPPPPADP--------SSPRKRPRPSR 373
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907126631  533 SPQRPGWSRSRNTqrrgrsrsarrGRSHSRSPATRGRSRSRTPAR-RGRSRSRTPARRRSRSRTPARRR 600
Cdd:PHA03307   374 APSSPAASAGRPT-----------RRRARAAVAGRARRRDATGRFpAGRPRPSPLDAGAASGAFYARYP 431
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
499-603 1.53e-05

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 50.28  E-value: 1.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  499 KRGHSRSRSPQWRRSRSAQRWgKSRSPQRRGRSRSpqRPGWSRSRNtqrrgrSRSARRGRSHSRSPATRGRSRSRTPARR 578
Cdd:TIGR01642   12 SRGRDRDRSSERPRRRSRDRS-RFRDRHRRSRERS--YREDSRPRD------RRRYDSRSPRSLRYSSVRRSRDRPRRRS 82
                           90       100
                   ....*....|....*....|....*
gi 1907126631  579 GRSRSRTPARRRSRSRTPARRRSRS 603
Cdd:TIGR01642   83 RSVRSIEQHRRRLRDRSPSNQWRKD 107
PRK12678 PRK12678
transcription termination factor Rho; Provisional
400-610 4.68e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 48.75  E-value: 4.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  400 GCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAKRDKSHSHTPSHRA 479
Cdd:PRK12678    62 GAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGA 141
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  480 GRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRS 559
Cdd:PRK12678   142 ARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRR 221
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907126631  560 HSRSPATRGRSRSRTPARRGRSRSRTPARRR-----SRSRTPARRRSRSRTPARRG 610
Cdd:PRK12678   222 DGGDRRGRRRRRDRRDARGDDNREDRGDRDGddgegRGGRRGRRFRDRDRRGRRGG 277
PHA03247 PHA03247
large tegument protein UL36; Provisional
1981-2441 4.74e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 4.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 1981 RSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRAARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVA 2060
Cdd:PHA03247  2583 TSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVS 2662
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2061 LSSsRMSCFSRPSMSPTPLDRCRSPGMLEPLGS----ARTPmsvlqqtggsmmdGPGPRIPDHPRSSVPENHAQSRIALA 2136
Cdd:PHA03247  2663 RPR-RARRLGRAAQASSPPQRPRRRAARPTVGSltslADPP-------------PPPPTPEPAPHALVSATPLPPGPAAA 2728
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2137 LTAISLGTARPPPSMSAAGLAARMSqvPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTSAIPASVNLADSRTPAA 2216
Cdd:PHA03247  2729 RQASPALPAAPAPPAVPAGPATPGG--PARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD 2806
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2217 AAAMnlASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALA-ALSLTGSGTP----------------PTAANYPSSS 2279
Cdd:PHA03247  2807 PPAA--VLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPpSLPLGGSVAPggdvrrrppsrspaakPAAPARPPVR 2884
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2280 R------------------------TPQAPTPANLVVGPRSAHGTAPVNIAGSRTPAGLAPTNLSS-------------- 2321
Cdd:PHA03247  2885 RlarpavsrstesfalppdqperppQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAgagepsgavpqpwl 2964
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2322 --------------------SRMAPALSGANLTSPRVPlsaydRVSGRTSPLMLDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PHA03247  2965 galvpgrvavprfrvpqpapSREAPASSTPPLTGHSLS-----RVSSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDA 3039
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907126631 2382 PASRM-----VQASSQSLLP-----PAQDRPRSPVPSAFSDQS-RSVVQTTPVAGSQSLSSGTVAKSTSSA 2441
Cdd:PHA03247  3040 DSLFDsdserSDLEALDPLPpephdPFAHEPDPATPEAGARESpSSQFGPPPLSANAALSRRYVRSTGRSA 3110
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2200-2425 2.53e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.41  E-value: 2.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2200 SAIPASVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAAL------SLTGSGTPPTAA 2273
Cdd:PRK12323   372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALaaarqaSARGPGGAPAPA 451
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2274 NYPSSSRTPQAPTPANLVVGPRSAHGTAPVNIAGSRTPAGLAPTNLSSSRMAPALSGAnltSPRVPLSAYDRVSGRTSPl 2353
Cdd:PRK12323   452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASP---APAQPDAAPAGWVAESIP- 527
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907126631 2354 mldrarsRTPPSAPSQSRMTSERERAPSPASRMVQASSQSLLPPAQDRPRSPVPSAFSDQSRSVVQTTPVAG 2425
Cdd:PRK12323   528 -------DPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARLPVRG 592
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2164-2481 3.17e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 3.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2164 PAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTSAIPASVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPA 2243
Cdd:PHA03307    61 ACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRP 140
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2244 ASAVNLAGARTPAALAAlsltgSGTPPTAANYPSSSRTPQAPTPANLVVGPRSAHGTAPVNIAGSRTPAGLAPTNLSSSR 2323
Cdd:PHA03307   141 VGSPGPPPAASPPAAGA-----SPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISA 215
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2324 MAPALSGANLTSPRVPLSAYDRVSGRTSPLMLDRA-RSRTPPSAPSQSRMTSERERAPSPASRMVQASSQSllPPAQDRP 2402
Cdd:PHA03307   216 SASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGpENECPLPRPAPITLPTRIWEASGWNGPSSRPGPAS--SSSSPRE 293
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2403 RSPVPSAFSDQSRSVVQTTPVAGSQSLS--SGTVAKSTSSASDHNGMLSGPAPGISHAEGGEPPASTGAQQPSTLAALQP 2480
Cdd:PHA03307   294 RSPSPSPSSPGSGPAPSSPRASSSSSSSreSSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSR 373

                   .
gi 1907126631 2481 A 2481
Cdd:PHA03307   374 A 374
PRK12678 PRK12678
transcription termination factor Rho; Provisional
380-592 4.59e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 45.67  E-value: 4.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  380 AAIPSSQEPVNPSSEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREiSSSPTSKN 459
Cdd:PRK12678    65 AAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGE-AARRGAAR 143
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  460 RSHGRAKRDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR-WGKSRSPQRRGRSRSPQRPG 538
Cdd:PRK12678   144 KAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDrDRRDRREQGDRREERGRRDG 223
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907126631  539 WSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSR 592
Cdd:PRK12678   224 GDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGG 277
PRK12678 PRK12678
transcription termination factor Rho; Provisional
379-604 4.63e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 45.67  E-value: 4.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  379 LAAIPSSQEP-VNPSSEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTS 457
Cdd:PRK12678    52 IAAIKEARGGgAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERR 131
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  458 KNRSHGRAKRDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRP 537
Cdd:PRK12678   132 ERGEAARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQ 211
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907126631  538 GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTpARRRSRSRTPARRRSRSR 604
Cdd:PRK12678   212 GDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRG-GRRGRRFRDRDRRGRRGG 277
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2143-2352 5.38e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.25  E-value: 5.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2143 GTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTSAIPASVNLADSRTPAAAAAMNL 2222
Cdd:PRK12323   370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2223 ASPRTAVAPSAVN---LADPRTPAASAVNLAGARTPAALAALSltGSGTPP---TAANYPSSSRTPQAPTPANLVVGPRS 2296
Cdd:PRK12323   450 PAPAPAAAPAAAArpaAAGPRPVAAAAAAAPARAAPAAAPAPA--DDDPPPweeLPPEFASPAPAQPDAAPAGWVAESIP 527
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907126631 2297 AHGTAPvniagsrtPAGLAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTSP 2352
Cdd:PRK12323   528 DPATAD--------PDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2020-2411 9.55e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.78  E-value: 9.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2020 LTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALSSSRMSCFSRPSMSPTPldrcRSPGMLEPLGSARTPms 2099
Cdd:PHA03307    50 LAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTP----PGPSSPDPPPPTPPP-- 123
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2100 vlqqtgGSMMDGPGPRIPDHPRSSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAAN 2179
Cdd:PHA03307   124 ------ASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPST 197
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2180 LASRIPAASAAAMNLASARTSAiPASVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPAASavnLAGARTPAALA 2259
Cdd:PHA03307   198 PPAAASPRPPRRSSPISASASS-PAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAP---ITLPTRIWEAS 273
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2260 ALSLTGSGTPPTAANYPSSSRTPqAPTPANLVVGPRSAHGTAPVNIAGSRTPAGLAPTNLS-SSRMAPALSGANLTSPRV 2338
Cdd:PHA03307   274 GWNGPSSRPGPASSSSSPRERSP-SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSeSSRGAAVSPGPSPSRSPS 352
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907126631 2339 PLSAYDRVSGRTSPlmlDRARSRTPPSAPSQSRMTSERERA-PSPASRMVQASSQSLLPPAQDRPRSPVPSAFS 2411
Cdd:PHA03307   353 PSRPPPPADPSSPR---KRPRPSRAPSSPAASAGRPTRRRArAAVAGRARRRDATGRFPAGRPRPSPLDAGAAS 423
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2223-2431 1.11e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.48  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2223 ASPRTAVAPSAVNLADPRTPAASAVnlAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPTPANLVVGPRSAHGTAP 2302
Cdd:PRK12323   372 AGPATAAAAPVAQPAPAAAAPAAAA--PAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2303 VNIAGSRTPAGLAPTNLSSSRMAPALSgANLTSPRVPLSAYDRVSGRTSPLM-LDRARSRTPPSAPSQSRMTSERERAPS 2381
Cdd:PRK12323   450 PAPAPAAAPAAAARPAAAGPRPVAAAA-AAAPARAAPAAAPAPADDDPPPWEeLPPEFASPAPAQPDAAPAGWVAESIPD 528
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2382 PASRMVQASSQSLLPPAqdrPRSPVPSAFSDQSRSVVQTTPVAGSQSLSS 2431
Cdd:PRK12323   529 PATADPDDAFETLAPAP---AAAPAPRAAAATEPVVAPRPPRASASGLPD 575
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
511-608 1.14e-03

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 44.14  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  511 RRSRSAQRWGKSRSPQRRGRSRSPQRPGwSRSRNTQRRGRSRSARRgrshsrspatRGRSRSRTPARRGRSRSRTPaRRR 590
Cdd:TIGR01622    2 YRDRERERLRDSSSAGDRDRRRDKGRER-SRDRSRDRERSRSRRRD----------RHRDRDYYRGRERRSRSRRP-NRR 69
                           90
                   ....*....|....*...
gi 1907126631  591 SRSRTPARRRSRSRTPAR 608
Cdd:TIGR01622   70 YRPREKRRRRGDSYRRRR 87
PHA03247 PHA03247
large tegument protein UL36; Provisional
165-462 1.20e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  165 PEPPKPYSLVRETSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKK 244
Cdd:PHA03247  2702 PPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPR 2781
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKI------HTTALTGQSPPLASGHQGEGDAP--SVEPGAT 316
Cdd:PHA03247  2782 RLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASpagplpPPTSAQPTAPPPPPGPPPPSLPLggSVAPGGD 2861
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  317 NIQQPSSPAPSTKQSSSPYEDKDKKEKSAVRPSPSPERSSTGPELPAPTPllveqhvDSPRPLAAIPSSQEPVNPSSeAS 396
Cdd:PHA03247  2862 VRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQP-------QAPPPPQPQPQPPPPPQPQP-PP 2933
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907126631  397 PTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSH 462
Cdd:PHA03247  2934 PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGH 2999
RSRP pfam17069
Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.
436-604 1.21e-03

Arginine/Serine-Rich protein 1; RSRP1 is an eukaryotic protein family. Its function is unknown.


Pssm-ID: 293674 [Multi-domain]  Cd Length: 299  Bit Score: 43.61  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  436 PESLKPTPAPGSRREISSS-PTSKNRSHGRAKRDKSHSHTPSHRAGRSRS-PATKRGRSRSRTPTKR---GHSRSRSPQW 510
Cdd:pfam17069   10 PGSPQEKKSPSTSSSGSSSrLSSRSRSRSSSRSSRSHSRSSSRFSSRSRSrPRRSRSRSRSRRRHQRkyrRYSRSYSRSR 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  511 RRSRSAQRWGKSRSPQRRGRSRSPQRpgwSRSRNTQRRGRSRSARRGRSHSRSpatrGRSRSRTPARRGRSRSRTpaRRR 590
Cdd:pfam17069   90 SRSRRRRYYRRSRYRYSRRYYRSPSR---SRSRSRSRSRGRSYYAIWRGSRYY----GFGRTVYPERSPRWRSRS--RTR 160
                          170
                   ....*....|....
gi 1907126631  591 SRSRTPARRRSRSR 604
Cdd:pfam17069  161 SRSRTPFRLSEKER 174
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2104-2402 1.35e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.07  E-value: 1.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2104 TGGSmmdGPGPRIPDHPRSSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASR 2183
Cdd:PRK07003   363 TGGG---APGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRG 439
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2184 IPAASAAAMNLASARTSAIPASVNLADSRTPAAAAAMNlASPRTAVAPSAVNLADPRTPAASAVNLAGARTPAALAALSL 2263
Cdd:PRK07003   440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSA-SAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASR 518
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631 2264 TGSGTPPTAANYPSSSRTPQAPTPANlvvgpRSAHGTAPVNI---AGSRTPAGlaptnlsSSRMAPALSGANLTSPRVPL 2340
Cdd:PRK07003   519 EDAPAAAAPPAPEARPPTPAAAAPAA-----RAGGAAAALDVlrnAGMRVSSD-------RGARAAAAAKPAAAPAAAPK 586
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907126631 2341 SAYDRVSgrtSPLMLDRARSRTPPSAPSQSrmtsererAPSPASrmvqASSQSLLPPAQDRP 2402
Cdd:PRK07003   587 PAAPRVA---VQVPTPRARAATGDAPPNGA--------ARAEQA----AESRGAPPPWEDIP 633
PHA03247 PHA03247
large tegument protein UL36; Provisional
162-610 1.44e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  162 QIAPEPPKPYSLVRETsssRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSK 241
Cdd:PHA03247  2572 RPAPRPSEPAVTSRAR---RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPP 2648
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  242 DKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKIHTTALTGQSPPlasghqgeGDAPSVEPGATNIQQP 321
Cdd:PHA03247  2649 PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP--------PPTPEPAPHALVSATP 2720
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  322 SSPAPSTKQSSSPyedkdkkeksAVRPSPSPERSSTGPELPAPtpllvEQHVDSPRPLAAIPSSQEPVNPSSEASPTrgc 401
Cdd:PHA03247  2721 LPPGPAAARQASP----------ALPAAPAPPAVPAGPATPGG-----PARPARPPTTAGPPAPAPPAAPAAGPPRR--- 2782
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  402 SPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAKRDKSHSHT-----PS 476
Cdd:PHA03247  2783 LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSvapggDV 2862
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  477 HRAGRSRSPATK---RGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS 553
Cdd:PHA03247  2863 RRRPPSRSPAAKpaaPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907126631  554 ARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPaRRRSRSRTPARRRSRSRTPARRG 610
Cdd:PHA03247  2943 LAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVP-RFRVPQPAPSREAPASSTPPLTG 2998
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
313-444 3.25e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.84  E-value: 3.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  313 PGATNIQQPSSPAPStkQSSSPYEdkdkkEKSAVRPSPSPERSSTGPELPAPTPllVEQHVDSPRPLAAIPSSQEPVNPS 392
Cdd:PRK14971   370 SGGRGPKQHIKPVFT--QPAAAPQ-----PSAAAAASPSPSQSSAAAQPSAPQS--ATQPAGTPPTVSVDPPAAVPVNPP 440
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907126631  393 SEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPA 444
Cdd:PRK14971   441 STAPQAVRPAQFKEEKKIPVSKVSSLGPSTLRPIQEKAEQATGNIKEAPTGT 492
PRK12678 PRK12678
transcription termination factor Rho; Provisional
359-590 3.52e-03

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 42.58  E-value: 3.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  359 PELPAPTPLLVEQHVDSPRPLAAIPSSQEPVNPSSEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPES 438
Cdd:PRK12678    68 ATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAARKAGE 147
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  439 LKPTPAPGSRREISSSPTSKNRSHGRAKRDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR 518
Cdd:PRK12678   148 GGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRR 227
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907126631  519 WGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARrgrshsrspatRGRSRSRTPARRGRSRSRTPARRR 590
Cdd:PRK12678   228 GRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGR-----------RFRDRDRRGRRGGDGGNEREPELR 288
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
350-726 4.42e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.47  E-value: 4.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  350 PSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEPVNPSSEASPTRGCSPPKSPEKPPQSTSSEScpPSPQPTKGS 429
Cdd:PHA03307    39 SQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPT--PPGPSSPDP 116
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  430 RHASSSPESLKPTPAPGSRREISSSPTSKNRSHGRAKR-DKSHSHTPSHRAG-RSRSPATKRGRSRSRTPTKRGHSR--S 505
Cdd:PHA03307   117 PPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAaGASPAAVASDAASsRQAALPLSSPEETARAPSSPPAEPppS 196
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  506 RSPQWRRSRSAQRWGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 585
Cdd:PHA03307   197 TPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWN 276
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  586 PARRR---SRSRTPARRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSQARRSGRSRSRTPArrsgrsrsrtpa 662
Cdd:PHA03307   277 GPSSRpgpASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPG------------ 344
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907126631  663 rRGRSRSRTPARRSARSRSRTPARRGRSRSRTPARRRSRSRSLVRRGRShSRTPQRRGRSGSSS 726
Cdd:PHA03307   345 -PSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA-AVAGRARRRDATGR 406
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
309-462 6.35e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.83  E-value: 6.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  309 PSVEPGATNIQQPSSPAP--STKQSSSPYEDKDKKEKSAVRPSPSPERSST---GPELPAPTPLLV--EQHVDSPRPLAA 381
Cdd:pfam05109  449 PSSTHVPTNLTAPASTGPtvSTADVTSPTPAGTTSGASPVTPSPSPRDNGTeskAPDMTSPTSAVTtpTPNATSPTPAVT 528
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  382 IPSSQEPVNPSSEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESlkPTPAPGSRREISSSPTSKNRS 461
Cdd:pfam05109  529 TPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTT--PTPNATSPTVGETSPQANTTN 606

                   .
gi 1907126631  462 H 462
Cdd:pfam05109  607 H 607
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
525-608 7.58e-03

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 41.42  E-value: 7.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907126631  525 PQRRGRSRSPQRP-GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPA-----RRGRSRSRTPARRRSRSR-TPA 597
Cdd:TIGR01642   12 SRGRDRDRSSERPrRRSRDRSRFRDRHRRSRERSYREDSRPRDRRRYDSRSPRslrysSVRRSRDRPRRRSRSVRSiEQH 91
                           90
                   ....*....|.
gi 1907126631  598 RRRSRSRTPAR 608
Cdd:TIGR01642   92 RRRLRDRSPSN 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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