|
Name |
Accession |
Description |
Interval |
E-value |
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
176-342 |
6.58e-36 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 133.20 E-value: 6.58e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 176 RVSLTIGVAGVGKTTLVRHFVHCWARGQVGKGFSRVLPLTFRDLNTYEK-LSADRLIQSIFSSIGEA-----SLVATAPD 249
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGFDFVFFLPCRELSRSGNaRSLADLLFSQWPEPAAPvsevwAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 250 RVLLVLDGLDECKTPLEFSNTmacsdpkkEIQVDHLITNIIRGNLFPEISVWITSRPSAAGQIPGGLVD-RMTEIRGLTE 328
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDG--------PCPVLTLLSSLLRKKLLPGASLLLTVRPDALRDLRRGLEEpRYLEVRGFSE 152
|
170
....*....|....
gi 1907117907 329 EEIKVCLEQMFPEE 342
Cdd:pfam05729 153 SDRKQYVRKYFSDE 166
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
678-815 |
3.51e-28 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 118.35 E-value: 3.51e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 678 SLRLDNNQFQDPVMELLGSVLSGkDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKI 757
Cdd:COG5238 268 TLYLSGNQIGAEGAIALAKALQG-NTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQE 346
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907117907 758 NRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNR 815
Cdd:COG5238 347 NTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTNR 404
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
28-776 |
1.31e-19 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 94.49 E-value: 1.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 28 ALYSQLLAANTDSTRKQEVWTDRETCLAYSVGSPAEQVKALVDLLAGKGSQLLQVRDKMPDSPLGSQSNESRIPKHSEAL 107
Cdd:COG5635 29 LAALLLLALVALGLALLALLDLLLADLGALLALVSRSALSAAALLARALSALLLVLLLLESLLLLLLLLLLLAEALLALL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 108 LSRVGNDPELGSPSHRLASLMLVEGLTDLQLKEHDFTQVEAtrgvwhpaRVITLDRLFLPLSRVSIPPRVSLT------- 180
Cdd:COG5635 109 ELAALLKAVLLSLSGGSDLVLLLSESDLLLALLILLLDADG--------LLVSLDDLYVPLNLLERIESLKRLelleakk 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 181 -----IGVAGVGKTTLVRHFVHCWARGqvGKGFSRVLPL--TFRDLNTYEKLSA--DRLIQSIFSSIGEASLVATAPDRV 251
Cdd:COG5635 181 krlliLGEPGSGKTTLLRYLALELAER--YLDAEDPIPIliELRDLAEEASLEDllAEALEKRGGEPEDALERLLRNGRL 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 252 LLVLDGLDECKTPLEFSntmacsdpkkeiQVDHLITNIIRGnlFPEISVWITSRPSAAGQIPGGLVDRMtEIRGLTEEEI 331
Cdd:COG5635 259 LLLLDGLDEVPDEADRD------------EVLNQLRRFLER--YPKARVIITSRPEGYDSSELEGFEVL-ELAPLSDEQI 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 332 KVCLEQMFPEEQNLLGQVLSQVQANRALYLMCTVPAFCRLtgLALGHLYRTRlavqdielpLPQTLCELYSWYFRMALgg 411
Cdd:COG5635 324 EEFLKKWFEATERKAERLLEALEENPELRELARNPLLLTL--LALLLRERGE---------LPDTRAELYEQFVELLL-- 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 412 EGQDKEKVSPRIKQVTQGARKMVgtLGRLAFHGLVKKKYVFYEQDMKAF---------GVDLALLQNTLCSCLLQREetl 482
Cdd:COG5635 391 ERWDEQRGLTIYRELSREELREL--LSELALAMQENGRTEFAREELEEIlreylgrrkDAEALLDELLLRTGLLVER--- 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 483 aSSVAYCFIHLSLQEFVAATYYYSASKRAIFDLFtesgmswprlgflahfrcaaqrATQAKDGRLDVFLRFLSGLLSPR- 561
Cdd:COG5635 466 -GEGRYSFAHRSFQEYLAARALVEELDEELLELL----------------------AEHLEDPRWREVLLLLAGLLDDVk 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 562 -----VNTLLAGSLLSQGEHQSYRDQVAEVLQGFLHPDAAVCARAINVLYCLSELRHTELACSVEEAMRSGTLAGMTSPS 636
Cdd:COG5635 523 qikelIDALLARDDAAALALAAALLLALLLALALLALLALLLLLRLLLALLALLLLALLLLLLLALLLALLALDLGLAAL 602
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 637 HRTALAYLLQMSDICSPEADFSLCLSQHVLQSLLPQLLYCQ--SLRLDNNQFQDPVMELLGSVLSGKDCRIRKISLAENQ 714
Cdd:COG5635 603 LLLLLLLLLLLLLLALALLLALLLLLLLLLLAELLLLALLAlvLLSLLLASRLLLITLLLLAAASAALLLLLLLLLAELL 682
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907117907 715 IGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGV 776
Cdd:COG5635 683 LALLALASLLLLLLLALALALALLLLAVLLAAALDLLLLLVLLLALLLVLALALSLLLLALA 744
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
662-820 |
2.21e-19 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 90.11 E-value: 2.21e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 662 SQHVLQSLLpQLLYCQSLRLDNNQFQDPVMELLGSVLSGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSN 741
Cdd:cd00116 97 GCGVLESLL-RSSSLQELKLNNNGLGDRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEALAKALRANRDLKELNLANN 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 742 SIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQ-NRSLKAL 820
Cdd:cd00116 176 GIGDAGIRALAEGLKANCNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASALLSpNISLLTL 255
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
492-617 |
4.01e-18 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 80.80 E-value: 4.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 492 HLSLQEFVAATYYYSASKRAIFDLFTESGMSWPRLGFlahfRCAAQRATQAKDGRLDVFLRFLSGLLSPRVNTLLAGSL- 570
Cdd:pfam17776 1 HLSFQEFFAALFYVLSFKEEKSNPLKEFFGLRKRESL----KSLLDKALKSKNGHLDLFLRFLFGLLNEENQRLLEGLLg 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1907117907 571 --LSQGEHQSYRDQVAEVLQGFLHPDaavcaRAINVLYCLSELRHTELA 617
Cdd:pfam17776 77 ckLSSEIKQELLQWIKSLIQKELSSE-----RFLNLFHCLYELQDESFV 120
|
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
730-756 |
2.95e-04 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 38.54 E-value: 2.95e-04
|
| LRR_6 |
pfam13516 |
Leucine Rich repeat; |
729-752 |
4.79e-03 |
|
Leucine Rich repeat;
Pssm-ID: 463907 [Multi-domain] Cd Length: 24 Bit Score: 34.90 E-value: 4.79e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
176-342 |
6.58e-36 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 133.20 E-value: 6.58e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 176 RVSLTIGVAGVGKTTLVRHFVHCWARGQVGKGFSRVLPLTFRDLNTYEK-LSADRLIQSIFSSIGEA-----SLVATAPD 249
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGFDFVFFLPCRELSRSGNaRSLADLLFSQWPEPAAPvsevwAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 250 RVLLVLDGLDECKTPLEFSNTmacsdpkkEIQVDHLITNIIRGNLFPEISVWITSRPSAAGQIPGGLVD-RMTEIRGLTE 328
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDG--------PCPVLTLLSSLLRKKLLPGASLLLTVRPDALRDLRRGLEEpRYLEVRGFSE 152
|
170
....*....|....
gi 1907117907 329 EEIKVCLEQMFPEE 342
Cdd:pfam05729 153 SDRKQYVRKYFSDE 166
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
678-815 |
3.51e-28 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 118.35 E-value: 3.51e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 678 SLRLDNNQFQDPVMELLGSVLSGkDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKI 757
Cdd:COG5238 268 TLYLSGNQIGAEGAIALAKALQG-NTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQE 346
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907117907 758 NRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNR 815
Cdd:COG5238 347 NTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQTNR 404
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
678-820 |
9.05e-26 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 111.04 E-value: 9.05e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 678 SLRLDNNQFQDPVMELLGSVLSGKDcRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKI 757
Cdd:COG5238 212 TLWLKRNPIGDEGAEILAEALKGNK-SLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQG 290
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907117907 758 NRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKAL 820
Cdd:COG5238 291 NTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
678-820 |
4.47e-25 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 109.11 E-value: 4.47e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 678 SLRLDNNQFQDPVMELLGSVLSGKDcRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKI 757
Cdd:COG5238 240 TLDLSNNQIGDEGVIALAEALKNNT-TVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQG 318
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907117907 758 NRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKAL 820
Cdd:COG5238 319 NKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLREL 381
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
665-820 |
7.74e-25 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 108.34 E-value: 7.74e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 665 VLQSLLPQLLYCQSLRLDNNQFQDPVMELLGSVLSGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIG 744
Cdd:COG5238 142 NLIQVLKDPLGGNAVHLLGLAARLGLLAAISMAKALQNNSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIG 221
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907117907 745 PPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKAL 820
Cdd:COG5238 222 DEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSL 297
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
677-820 |
1.09e-22 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 101.79 E-value: 1.09e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 677 QSLRLDNNQFQDPVMELLGSVLSgKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALK 756
Cdd:COG5238 183 ETVYLGCNQIGDEGIEELAEALT-QNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALK 261
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907117907 757 INRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKAL 820
Cdd:COG5238 262 NNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTL 325
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
28-776 |
1.31e-19 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 94.49 E-value: 1.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 28 ALYSQLLAANTDSTRKQEVWTDRETCLAYSVGSPAEQVKALVDLLAGKGSQLLQVRDKMPDSPLGSQSNESRIPKHSEAL 107
Cdd:COG5635 29 LAALLLLALVALGLALLALLDLLLADLGALLALVSRSALSAAALLARALSALLLVLLLLESLLLLLLLLLLLAEALLALL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 108 LSRVGNDPELGSPSHRLASLMLVEGLTDLQLKEHDFTQVEAtrgvwhpaRVITLDRLFLPLSRVSIPPRVSLT------- 180
Cdd:COG5635 109 ELAALLKAVLLSLSGGSDLVLLLSESDLLLALLILLLDADG--------LLVSLDDLYVPLNLLERIESLKRLelleakk 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 181 -----IGVAGVGKTTLVRHFVHCWARGqvGKGFSRVLPL--TFRDLNTYEKLSA--DRLIQSIFSSIGEASLVATAPDRV 251
Cdd:COG5635 181 krlliLGEPGSGKTTLLRYLALELAER--YLDAEDPIPIliELRDLAEEASLEDllAEALEKRGGEPEDALERLLRNGRL 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 252 LLVLDGLDECKTPLEFSntmacsdpkkeiQVDHLITNIIRGnlFPEISVWITSRPSAAGQIPGGLVDRMtEIRGLTEEEI 331
Cdd:COG5635 259 LLLLDGLDEVPDEADRD------------EVLNQLRRFLER--YPKARVIITSRPEGYDSSELEGFEVL-ELAPLSDEQI 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 332 KVCLEQMFPEEQNLLGQVLSQVQANRALYLMCTVPAFCRLtgLALGHLYRTRlavqdielpLPQTLCELYSWYFRMALgg 411
Cdd:COG5635 324 EEFLKKWFEATERKAERLLEALEENPELRELARNPLLLTL--LALLLRERGE---------LPDTRAELYEQFVELLL-- 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 412 EGQDKEKVSPRIKQVTQGARKMVgtLGRLAFHGLVKKKYVFYEQDMKAF---------GVDLALLQNTLCSCLLQREetl 482
Cdd:COG5635 391 ERWDEQRGLTIYRELSREELREL--LSELALAMQENGRTEFAREELEEIlreylgrrkDAEALLDELLLRTGLLVER--- 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 483 aSSVAYCFIHLSLQEFVAATYYYSASKRAIFDLFtesgmswprlgflahfrcaaqrATQAKDGRLDVFLRFLSGLLSPR- 561
Cdd:COG5635 466 -GEGRYSFAHRSFQEYLAARALVEELDEELLELL----------------------AEHLEDPRWREVLLLLAGLLDDVk 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 562 -----VNTLLAGSLLSQGEHQSYRDQVAEVLQGFLHPDAAVCARAINVLYCLSELRHTELACSVEEAMRSGTLAGMTSPS 636
Cdd:COG5635 523 qikelIDALLARDDAAALALAAALLLALLLALALLALLALLLLLRLLLALLALLLLALLLLLLLALLLALLALDLGLAAL 602
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 637 HRTALAYLLQMSDICSPEADFSLCLSQHVLQSLLPQLLYCQ--SLRLDNNQFQDPVMELLGSVLSGKDCRIRKISLAENQ 714
Cdd:COG5635 603 LLLLLLLLLLLLLLALALLLALLLLLLLLLLAELLLLALLAlvLLSLLLASRLLLITLLLLAAASAALLLLLLLLLAELL 682
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907117907 715 IGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGV 776
Cdd:COG5635 683 LALLALASLLLLLLLALALALALLLLAVLLAAALDLLLLLVLLLALLLVLALALSLLLLALA 744
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
662-820 |
2.21e-19 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 90.11 E-value: 2.21e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 662 SQHVLQSLLpQLLYCQSLRLDNNQFQDPVMELLGSVLSGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSN 741
Cdd:cd00116 97 GCGVLESLL-RSSSLQELKLNNNGLGDRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEALAKALRANRDLKELNLANN 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 742 SIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQ-NRSLKAL 820
Cdd:cd00116 176 GIGDAGIRALAEGLKANCNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASALLSpNISLLTL 255
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
677-817 |
1.54e-18 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 89.08 E-value: 1.54e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 677 QSLRLDNNQFQDPVMELLGSVLSGKDCrIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALK 756
Cdd:COG5238 295 TSLDLSVNRIGDEGAIALAEGLQGNKT-LHTLNLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLE 373
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117907 757 INRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISmLQLQKNLIGLIGAQQMADALKQNRSL 817
Cdd:COG5238 374 GNTTLRELNLGKNNIGKQGAEALIDALQTNRLHT-LILDGNLIGAEAQQRLEQLLERIKSV 433
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
652-820 |
2.62e-18 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 86.64 E-value: 2.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 652 SPEADFSLCLSQHVLQSLLPQLlycQSLRLDNNQFQDPVMELLGSVLSgKDCRIRKISLAENQIGNKGAKALARSLLVNR 731
Cdd:cd00116 118 NGLGDRGLRLLAKGLKDLPPAL---EKLVLGRNRLEGASCEALAKALR-ANRDLKELNLANNGIGDAGIRALAEGLKANC 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 732 SLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVS-NQTISMLQLQKNLIGLIGAQQMADA 810
Cdd:cd00116 194 NLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASALLSpNISLLTLSLSCNDITDDGAKDLAEV 273
|
170
....*....|
gi 1907117907 811 LKQNRSLKAL 820
Cdd:cd00116 274 LAEKESLLEL 283
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
666-815 |
3.49e-18 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 86.26 E-value: 3.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 666 LQSLLPQLLYCQSLRLDNNQFQDPVMELLGSVLSgKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGP 745
Cdd:cd00116 157 LAKALRANRDLKELNLANNGIGDAGIRALAEGLK-ANCNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTD 235
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907117907 746 PGAKALADALK-INRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNR 815
Cdd:cd00116 236 AGAAALASALLsPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESLLEPG 306
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
492-617 |
4.01e-18 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 80.80 E-value: 4.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 492 HLSLQEFVAATYYYSASKRAIFDLFTESGMSWPRLGFlahfRCAAQRATQAKDGRLDVFLRFLSGLLSPRVNTLLAGSL- 570
Cdd:pfam17776 1 HLSFQEFFAALFYVLSFKEEKSNPLKEFFGLRKRESL----KSLLDKALKSKNGHLDLFLRFLFGLLNEENQRLLEGLLg 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1907117907 571 --LSQGEHQSYRDQVAEVLQGFLHPDaavcaRAINVLYCLSELRHTELA 617
Cdd:pfam17776 77 ckLSSEIKQELLQWIKSLIQKELSSE-----RFLNLFHCLYELQDESFV 120
|
|
| NOD2_WH |
pfam17779 |
NOD2 winged helix domain; This winged helix domain is found in the NOD2 protein. Its molecular ... |
432-490 |
1.92e-11 |
|
NOD2 winged helix domain; This winged helix domain is found in the NOD2 protein. Its molecular function is not known.
Pssm-ID: 465501 Cd Length: 57 Bit Score: 59.89 E-value: 1.92e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1907117907 432 KMVGTLGRLAFHGLVKKKYVFYEQDMKAFGVDLALLQNTLCSCLLQREETLASsvAYCF 490
Cdd:pfam17779 1 KLLLKLGKLAFEGLWKKKLVFSEEDLKEYGLDESDLSSGLLTEILQKDLGCEK--VYSF 57
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
668-820 |
2.20e-07 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 53.51 E-value: 2.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 668 SLLPQLLYCQSLRLDNNQFQDPVMELLGSVL-SGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPP 746
Cdd:cd00116 17 ELLPKLLCLQVLRLEGNTLGEEAAKALASALrPQPSLKELCLSLNETGRIPRGLQSLLQGLTKGCGLQELDLSDNALGPD 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907117907 747 GAKALADALKiNRTLTSLSLQSNVIKDDGVMCVAEALVSNQ-TISMLQLQKNLIGLIGAQQMADALKQNRSLKAL 820
Cdd:cd00116 97 GCGVLESLLR-SSSLQELKLNNNGLGDRGLRLLAKGLKDLPpALEKLVLGRNRLEGASCEALAKALRANRDLKEL 170
|
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
730-756 |
2.95e-04 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 38.54 E-value: 2.95e-04
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
658-773 |
1.59e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 41.84 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907117907 658 SLCLSQHVLQSL---LPQLLYCQSLRLDNNQFQDpvmelLGSVLSGKDcRIRKISLAENQIgnkgaKALARSLLVNRSLI 734
Cdd:COG4886 117 SLDLSGNQLTDLpeeLANLTNLKELDLSNNQLTD-----LPEPLGNLT-NLKSLDLSNNQL-----TDLPEELGNLTNLK 185
|
90 100 110
....*....|....*....|....*....|....*....
gi 1907117907 735 TLDLRSNSIgppgaKALADALKINRTLTSLSLQSNVIKD 773
Cdd:COG4886 186 ELDLSNNQI-----TDLPEPLGNLTNLEELDLSGNQLTD 219
|
|
| LRR_6 |
pfam13516 |
Leucine Rich repeat; |
729-752 |
4.79e-03 |
|
Leucine Rich repeat;
Pssm-ID: 463907 [Multi-domain] Cd Length: 24 Bit Score: 34.90 E-value: 4.79e-03
|
| |
