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phosphatidate phosphatase LPIN1 isoform X11 [Mus musculus]
phosphatidate phosphatase( domain architecture ID 11151321)
phosphatidate phosphatase is a magnesium-dependent enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the metabolism of fatty acids at different levels
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
LNS2 | pfam08235 | LNS2 (Lipin/Ned1/Smp2); This domain is found in Saccharomyces cerevisiae protein SMP2, ... |
660-885 | 1.56e-141 | ||||
LNS2 (Lipin/Ned1/Smp2); This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain (Pfam: PF04571). SMP2 (also known as PAH1) is involved in plasmid maintenance and respiration, and has been identified as a Mg2+-dependent phosphatidate phosphatase (EC:3.1.3.4) that contains a haloacid dehalogenase (HAD)-like domain. Lipin proteins are involved in adipose tissue development and insulin resistance. : Pssm-ID: 462403 Cd Length: 226 Bit Score: 419.99 E-value: 1.56e-141
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Lipin_N | pfam04571 | lipin, N-terminal conserved region; Mutations in the lipin gene lead to fatty liver dystrophy ... |
1-107 | 2.05e-63 | ||||
lipin, N-terminal conserved region; Mutations in the lipin gene lead to fatty liver dystrophy in mice. The protein has been shown to be phosphorylated by the TOR Ser/Thr protein kinases in response to insulin stimulation. The conserved region is found at the N-terminus of the member proteins. : Pssm-ID: 461356 Cd Length: 103 Bit Score: 208.55 E-value: 2.05e-63
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Lipin_mid | pfam16876 | Lipin/Ned1/Smp2 multi-domain protein middle domain; This is a middle domain of lipins. Overall ... |
498-591 | 3.39e-43 | ||||
Lipin/Ned1/Smp2 multi-domain protein middle domain; This is a middle domain of lipins. Overall the enzyme acts as a magnesium-dependent phosphatidate phosphatase enzyme that catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. EC:5.2.1.8. : Pssm-ID: 465292 Cd Length: 98 Bit Score: 151.67 E-value: 3.39e-43
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Name | Accession | Description | Interval | E-value | ||||
LNS2 | pfam08235 | LNS2 (Lipin/Ned1/Smp2); This domain is found in Saccharomyces cerevisiae protein SMP2, ... |
660-885 | 1.56e-141 | ||||
LNS2 (Lipin/Ned1/Smp2); This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain (Pfam: PF04571). SMP2 (also known as PAH1) is involved in plasmid maintenance and respiration, and has been identified as a Mg2+-dependent phosphatidate phosphatase (EC:3.1.3.4) that contains a haloacid dehalogenase (HAD)-like domain. Lipin proteins are involved in adipose tissue development and insulin resistance. Pssm-ID: 462403 Cd Length: 226 Bit Score: 419.99 E-value: 1.56e-141
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LNS2 | smart00775 | This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal ... |
708-864 | 7.72e-78 | ||||
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; SMP2 is involved in plasmid maintenance and respiration. Lipin proteins are involved in adipose tissue development and insulin resistance. Pssm-ID: 197870 Cd Length: 157 Bit Score: 249.88 E-value: 7.72e-78
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Lipin_N | pfam04571 | lipin, N-terminal conserved region; Mutations in the lipin gene lead to fatty liver dystrophy ... |
1-107 | 2.05e-63 | ||||
lipin, N-terminal conserved region; Mutations in the lipin gene lead to fatty liver dystrophy in mice. The protein has been shown to be phosphorylated by the TOR Ser/Thr protein kinases in response to insulin stimulation. The conserved region is found at the N-terminus of the member proteins. Pssm-ID: 461356 Cd Length: 103 Bit Score: 208.55 E-value: 2.05e-63
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Lipin_mid | pfam16876 | Lipin/Ned1/Smp2 multi-domain protein middle domain; This is a middle domain of lipins. Overall ... |
498-591 | 3.39e-43 | ||||
Lipin/Ned1/Smp2 multi-domain protein middle domain; This is a middle domain of lipins. Overall the enzyme acts as a magnesium-dependent phosphatidate phosphatase enzyme that catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. EC:5.2.1.8. Pssm-ID: 465292 Cd Length: 98 Bit Score: 151.67 E-value: 3.39e-43
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Name | Accession | Description | Interval | E-value | ||||
LNS2 | pfam08235 | LNS2 (Lipin/Ned1/Smp2); This domain is found in Saccharomyces cerevisiae protein SMP2, ... |
660-885 | 1.56e-141 | ||||
LNS2 (Lipin/Ned1/Smp2); This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain (Pfam: PF04571). SMP2 (also known as PAH1) is involved in plasmid maintenance and respiration, and has been identified as a Mg2+-dependent phosphatidate phosphatase (EC:3.1.3.4) that contains a haloacid dehalogenase (HAD)-like domain. Lipin proteins are involved in adipose tissue development and insulin resistance. Pssm-ID: 462403 Cd Length: 226 Bit Score: 419.99 E-value: 1.56e-141
|
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LNS2 | smart00775 | This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal ... |
708-864 | 7.72e-78 | ||||
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; SMP2 is involved in plasmid maintenance and respiration. Lipin proteins are involved in adipose tissue development and insulin resistance. Pssm-ID: 197870 Cd Length: 157 Bit Score: 249.88 E-value: 7.72e-78
|
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Lipin_N | pfam04571 | lipin, N-terminal conserved region; Mutations in the lipin gene lead to fatty liver dystrophy ... |
1-107 | 2.05e-63 | ||||
lipin, N-terminal conserved region; Mutations in the lipin gene lead to fatty liver dystrophy in mice. The protein has been shown to be phosphorylated by the TOR Ser/Thr protein kinases in response to insulin stimulation. The conserved region is found at the N-terminus of the member proteins. Pssm-ID: 461356 Cd Length: 103 Bit Score: 208.55 E-value: 2.05e-63
|
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Lipin_mid | pfam16876 | Lipin/Ned1/Smp2 multi-domain protein middle domain; This is a middle domain of lipins. Overall ... |
498-591 | 3.39e-43 | ||||
Lipin/Ned1/Smp2 multi-domain protein middle domain; This is a middle domain of lipins. Overall the enzyme acts as a magnesium-dependent phosphatidate phosphatase enzyme that catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. EC:5.2.1.8. Pssm-ID: 465292 Cd Length: 98 Bit Score: 151.67 E-value: 3.39e-43
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Blast search parameters | ||||
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