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Conserved domains on  [gi|1907199123|ref|XP_036011033|]
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GPI mannosyltransferase 3 isoform X2 [Mus musculus]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229536)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PMT_2 super family cl21590
Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are ...
 159-416 2.20e-52

Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are not captured by pfam02366.


The actual alignment was detected with superfamily member PLN02816:

Pssm-ID: 473917  Cd Length: 546  Bit Score: 184.08  E-value: 2.20e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 159 WTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRRLhiLLLTVLWTLLVYSMLGHKEFRF 238
Cdd:PLN02816  265 WVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK--LSALILWVLAIYSILGHKEFRF 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 239 IYPVLPFCMVFCGYSLAHLKT----------------------WR---KAALSFLLLSNVPLAFYTGLVHQRGTLDVMNH 293
Cdd:PLN02816  343 VLPVLPIALIFSGYAFAQMEVsgssssssvtkkkqvprqnhtkWSpklRLSVYFLLATNIPMALYMSLFHQRGTEDAMNY 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 294 IQKVCPRGpdpASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPdlTGKTQYLDEADMFYLNPLRWLQQEFHSNASLPTH 373
Cdd:PLN02816  423 LSDEAYKG---RVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDESDQFLVNPLGFASELARNWSEPPSH 497

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1907199123 374 LVTFNVLEKEINTFLTSGNYERAATFFHTHWP-ERRTGSHIHVY 416
Cdd:PLN02816  498 IVLFASEETKLRDFMIQHSFKEVRRFFHAHFKvDRDLQSSVVVY 541
 
Name Accession Description Interval E-value
PLN02816 PLN02816
mannosyltransferase
 159-416 2.20e-52

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 184.08  E-value: 2.20e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 159 WTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRRLhiLLLTVLWTLLVYSMLGHKEFRF 238
Cdd:PLN02816  265 WVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK--LSALILWVLAIYSILGHKEFRF 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 239 IYPVLPFCMVFCGYSLAHLKT----------------------WR---KAALSFLLLSNVPLAFYTGLVHQRGTLDVMNH 293
Cdd:PLN02816  343 VLPVLPIALIFSGYAFAQMEVsgssssssvtkkkqvprqnhtkWSpklRLSVYFLLATNIPMALYMSLFHQRGTEDAMNY 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 294 IQKVCPRGpdpASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPdlTGKTQYLDEADMFYLNPLRWLQQEFHSNASLPTH 373
Cdd:PLN02816  423 LSDEAYKG---RVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDESDQFLVNPLGFASELARNWSEPPSH 497

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1907199123 374 LVTFNVLEKEINTFLTSGNYERAATFFHTHWP-ERRTGSHIHVY 416
Cdd:PLN02816  498 IVLFASEETKLRDFMIQHSFKEVRRFFHAHFKvDRDLQSSVVVY 541
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 153-325 3.96e-47

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 166.77  E-value: 3.96e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 153 SFFTCRWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPR----RLHILLLTVLWTLLVY 228
Cdd:pfam03901 226 SYFYGRFVFTPLNFLKYNVLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLrkvsRLSQLLAPILIWLFIY 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 229 SMLGHKEFRFIYPVLPFCMVFCGYSLAHLK----TWRK--AALSFLLLSNVPLAFYTGLVHQRGTL----DVMNHIQKVC 298
Cdd:pfam03901 306 SLQPHKEERFLYPVYPLILLSAAIALTRLSrrswKVRKklSLLFLLLFFNVSLARLFGLVHQYGAPlavyDVMSFLNETP 385

                         170       180
                  ....*....|....*....|....*....
gi 1907199123 299 PRGPDPA--SASVFIMMPCHSTPYYSHVH 325
Cdd:pfam03901 386 RENRNPAgpPVNVCIGMECYSTPSSFFLH 414
 
Name Accession Description Interval E-value
PLN02816 PLN02816
mannosyltransferase
 159-416 2.20e-52

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 184.08  E-value: 2.20e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 159 WTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRRLhiLLLTVLWTLLVYSMLGHKEFRF 238
Cdd:PLN02816  265 WVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK--LSALILWVLAIYSILGHKEFRF 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 239 IYPVLPFCMVFCGYSLAHLKT----------------------WR---KAALSFLLLSNVPLAFYTGLVHQRGTLDVMNH 293
Cdd:PLN02816  343 VLPVLPIALIFSGYAFAQMEVsgssssssvtkkkqvprqnhtkWSpklRLSVYFLLATNIPMALYMSLFHQRGTEDAMNY 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 294 IQKVCPRGpdpASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPdlTGKTQYLDEADMFYLNPLRWLQQEFHSNASLPTH 373
Cdd:PLN02816  423 LSDEAYKG---RVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDESDQFLVNPLGFASELARNWSEPPSH 497

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1907199123 374 LVTFNVLEKEINTFLTSGNYERAATFFHTHWP-ERRTGSHIHVY 416
Cdd:PLN02816  498 IVLFASEETKLRDFMIQHSFKEVRRFFHAHFKvDRDLQSSVVVY 541
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 153-325 3.96e-47

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 166.77  E-value: 3.96e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 153 SFFTCRWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPR----RLHILLLTVLWTLLVY 228
Cdd:pfam03901 226 SYFYGRFVFTPLNFLKYNVLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLrkvsRLSQLLAPILIWLFIY 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199123 229 SMLGHKEFRFIYPVLPFCMVFCGYSLAHLK----TWRK--AALSFLLLSNVPLAFYTGLVHQRGTL----DVMNHIQKVC 298
Cdd:pfam03901 306 SLQPHKEERFLYPVYPLILLSAAIALTRLSrrswKVRKklSLLFLLLFFNVSLARLFGLVHQYGAPlavyDVMSFLNETP 385

                         170       180
                  ....*....|....*....|....*....
gi 1907199123 299 PRGPDPA--SASVFIMMPCHSTPYYSHVH 325
Cdd:pfam03901 386 RENRNPAgpPVNVCIGMECYSTPSSFFLH 414
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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