procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform X2 [Mus musculus]
prolyl hydroxylase family protein( domain architecture ID 10653727)
prolyl hydroxylase family protein similar to prolyl 3-hydroxylase 1, a member of the 2-oxoglutarate dioxygenase superfamily, plays a crucial role in collagen synthesis, folding, and assembly
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
P4Hc | smart00702 | Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of ... |
220-383 | 2.10e-19 | ||||
Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides. These are 2-oxoglutarate-dependent dioxygenases, requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as a cofactor. : Pssm-ID: 214780 Cd Length: 165 Bit Score: 84.36 E-value: 2.10e-19
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Name | Accession | Description | Interval | E-value | ||||
P4Hc | smart00702 | Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of ... |
220-383 | 2.10e-19 | ||||
Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides. These are 2-oxoglutarate-dependent dioxygenases, requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as a cofactor. Pssm-ID: 214780 Cd Length: 165 Bit Score: 84.36 E-value: 2.10e-19
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2OG-FeII_Oxy | pfam03171 | 2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and ... |
305-385 | 1.07e-09 | ||||
2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity EC:1.14.11.2 catalysing the reaction: Procollagen L-proline + 2-oxoglutarate + O2 <=> procollagen trans- 4-hydroxy-L-proline + succinate + CO2. The full enzyme consists of a alpha2 beta2 complex with the alpha subunit contributing most of the parts of the active site. The family also includes lysyl hydrolases, isopenicillin synthases and AlkB. Pssm-ID: 397334 [Multi-domain] Cd Length: 101 Bit Score: 55.15 E-value: 1.07e-09
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Name | Accession | Description | Interval | E-value | ||||
P4Hc | smart00702 | Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of ... |
220-383 | 2.10e-19 | ||||
Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides. These are 2-oxoglutarate-dependent dioxygenases, requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as a cofactor. Pssm-ID: 214780 Cd Length: 165 Bit Score: 84.36 E-value: 2.10e-19
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2OG-FeII_Oxy | pfam03171 | 2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and ... |
305-385 | 1.07e-09 | ||||
2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity EC:1.14.11.2 catalysing the reaction: Procollagen L-proline + 2-oxoglutarate + O2 <=> procollagen trans- 4-hydroxy-L-proline + succinate + CO2. The full enzyme consists of a alpha2 beta2 complex with the alpha subunit contributing most of the parts of the active site. The family also includes lysyl hydrolases, isopenicillin synthases and AlkB. Pssm-ID: 397334 [Multi-domain] Cd Length: 101 Bit Score: 55.15 E-value: 1.07e-09
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Blast search parameters | ||||
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