NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1907195237|ref|XP_036010534|]
View 

meiosis-specific nuclear structural protein 1 isoform X1 [Mus musculus]

Protein Classification

trichohyalin-plectin-homology domain domain-containing protein( domain architecture ID 12159040)

trichohyalin-plectin-homology domain (TPH) domain-containing protein similar to meiosis-specific nuclear structural protein 1, trichoplein keratin filament-binding protein, and cilia- and flagella-associated proteins

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 173-513 1.03e-65

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


:

Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 217.09  E-value: 1.03e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 173 VRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEK 252
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 253 QLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEF 332
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 333 ANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQD 412
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 413 FEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQ 492
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 1907195237 493 QRRQGCINEIIEEERLRLLKE 513
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 173-513 1.03e-65

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 217.09  E-value: 1.03e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 173 VRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEK 252
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 253 QLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEF 332
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 333 ANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQD 412
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 413 FEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQ 492
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 1907195237 493 QRRQGCINEIIEEERLRLLKE 513
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 117-408 9.67e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 9.67e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 117 RVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKER 196
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 197 AAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMID 276
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 277 EIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDfwRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQ 356
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEA--LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1907195237 357 RQNLLMKQLEETLRQRDDLEQVRQELyQEEQAEIIKLKVKEEAELRLRRQRE 408
Cdd:COG1196   454 LEEEEEALLELLAELLEEAALLEAAL-AELLEELAEAAARLLLLLEAEADYE 504
PTZ00121 PTZ00121
MAEBL; Provisional
 63-517 4.07e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 4.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237   63 KKRALSFSEKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRflrvLQNEQFELDMEEAIQKAEANKMLR 142
Cdd:PTZ00121  1277 ARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK----KKADAAKKKAEEAKKAAEAAKAEA 1352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  143 DRQLEQEERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKDA--MKYEQMKRDAEIERI 220
Cdd:PTZ00121  1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAakKKADEAKKKAEEKKK 1432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  221 MMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLEdqERRKQEAYEQLLKEKLMIDEIVRKiyEEDQVERQQKLEKKNAI 300
Cdd:PTZ00121  1433 ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE--EAKKADEAKKKAEEAKKADEAKKK--AEEAKKKADEAKKAAEA 1508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  301 QKYIEEFQRAQDfwrQKKREEME--EENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEE----TLRQRDD 374
Cdd:PTZ00121  1509 KKKADEAKKAEE---AKKADEAKkaEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEdknmALRKAEE 1585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  375 LEQVR-------------------QELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMALKELilqAAKEEEETFK 435
Cdd:PTZ00121  1586 AKKAEearieevmklyeeekkmkaEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL---KKAEEENKIK 1662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  436 KAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHA 515
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742


                   ..
gi 1907195237  516 AK 517
Cdd:PTZ00121  1743 KK 1744
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 165-489 1.37e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  165 KDKKMRQQVRENSIELRELEQKLKAA---YMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNK 241
Cdd:TIGR02168  664 GSAKTNSSILERRREIEELEEKIEELeekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  242 ERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQK---------LEKKNAIQKYIEEFQRAQD 312
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKeelkalreaLDELRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  313 FWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLmKQLEETLRQRDDLEQVRQELYQEEQAEIIK 392
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-SELEALLNERASLEEALALLRSELEELSEE 902

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  393 LKVKEEAELRLRRQREMKQDFEDQMALKeliLQAAKEEEETFkkamLAKFAEDDRIELMNAqkqrmkqLEHKRAVEKLIE 472
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELR---LEGLEVRIDNL----QERLSEEYSLTLEEA-------EALENKIEDDEE 968

                          330
                   ....*....|....*..
gi 1907195237  473 ERRsQFLADKQRELEEL 489
Cdd:TIGR02168  969 EAR-RRLKRLENKIKEL 984
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 173-513 1.03e-65

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 217.09  E-value: 1.03e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 173 VRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEK 252
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 253 QLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEF 332
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 333 ANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQD 412
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 413 FEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQ 492
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 1907195237 493 QRRQGCINEIIEEERLRLLKE 513
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 117-408 9.67e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 9.67e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 117 RVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKER 196
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 197 AAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMID 276
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 277 EIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDfwRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQ 356
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEA--LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1907195237 357 RQNLLMKQLEETLRQRDDLEQVRQELyQEEQAEIIKLKVKEEAELRLRRQRE 408
Cdd:COG1196   454 LEEEEEALLELLAELLEEAALLEAAL-AELLEELAEAAARLLLLLEAEADYE 504
PTZ00121 PTZ00121
MAEBL; Provisional
 63-517 4.07e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 4.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237   63 KKRALSFSEKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRflrvLQNEQFELDMEEAIQKAEANKMLR 142
Cdd:PTZ00121  1277 ARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK----KKADAAKKKAEEAKKAAEAAKAEA 1352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  143 DRQLEQEERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKDA--MKYEQMKRDAEIERI 220
Cdd:PTZ00121  1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAakKKADEAKKKAEEKKK 1432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  221 MMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLEdqERRKQEAYEQLLKEKLMIDEIVRKiyEEDQVERQQKLEKKNAI 300
Cdd:PTZ00121  1433 ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE--EAKKADEAKKKAEEAKKADEAKKK--AEEAKKKADEAKKAAEA 1508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  301 QKYIEEFQRAQDfwrQKKREEME--EENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEE----TLRQRDD 374
Cdd:PTZ00121  1509 KKKADEAKKAEE---AKKADEAKkaEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEdknmALRKAEE 1585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  375 LEQVR-------------------QELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMALKELilqAAKEEEETFK 435
Cdd:PTZ00121  1586 AKKAEearieevmklyeeekkmkaEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL---KKAEEENKIK 1662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  436 KAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHA 515
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742


                   ..
gi 1907195237  516 AK 517
Cdd:PTZ00121  1743 KK 1744
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 71-516 1.54e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 1.54e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  71 EKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRFLRVLQN-EQFELDMEEAIQKAEANKMLRDRQLEQE 149
Cdd:COG1196   267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERlEELEEELAELEEELEELEEELEELEEEL 346

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 150 ERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLL 229
Cdd:COG1196   347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 230 KEESAKQERRNKERAQYYLDLEKQLEDQERRKQEAyEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQR 309
Cdd:COG1196   427 EEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL-LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 310 AQDFWRQKKRE-------------------------------------EMEEENRKIIEFAniQEQREGERMARVHEIEE 352
Cdd:COG1196   506 FLEGVKAALLLaglrglagavavligveaayeaaleaalaaalqnivvEDDEVAAAAIEYL--KAAKAGRATFLPLDKIR 583

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 353 KRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMALKELILQAAKEEEE 432
Cdd:COG1196   584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 433 TFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQGCINEIIEEERLRLLK 512
Cdd:COG1196   664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743


                  ....
gi 1907195237 513 EHAA 516
Cdd:COG1196   744 EEEL 747
PTZ00121 PTZ00121
MAEBL; Provisional
 39-473 3.18e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.15  E-value: 3.18e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237   39 DAFATEAETHPAGGGGLKPTEMATKKRALSFSEKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRFLRV 118
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADE 1448

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  119 LQNEQFEL-DMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDK----KMRQQVRENSIELRELEQKLKAAYMN 193
Cdd:PTZ00121  1449 AKKKAEEAkKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKadeaKKAAEAKKKADEAKKAEEAKKADEAK 1528

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  194 KERAAQIVEkDAMKYEQMKRDAEIERimMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLED-QERRKQEAYEQLLKEK 272
Cdd:PTZ00121  1529 KAEEAKKAD-EAKKAEEKKKADELKK--AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaEEARIEEVMKLYEEEK 1605

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  273 LMIDEIVRKiyEEDQVERQQKLEKKNAIQKYIEEFQRAQdfwrqkkreemEEENRKiiefanIQEQREGERMARVHEIEE 352
Cdd:PTZ00121  1606 KMKAEEAKK--AEEAKIKAEELKKAEEEKKKVEQLKKKE-----------AEEKKK------AEELKKAEEENKIKAAEE 1666

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  353 KRVQRQNllMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMALKElilQAAKEEEE 432
Cdd:PTZ00121  1667 AKKAEED--KKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAE---EAKKEAEE 1741

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1907195237  433 TFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRA-VEKLIEE 473
Cdd:PTZ00121  1742 DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKeKEAVIEE 1783
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 159-516 3.87e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 3.87e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 159 LKHESLKDKKMRQQVRENSIELRELEQKLKAAymNKERAAQIVEKDAMKYEQMKRDAEIERIMmEEHDRLLKEESAKQER 238
Cdd:COG1196   213 ERYRELKEELKELEAELLLLKLRELEAELEEL--EAELEELEAELEELEAELAELEAELEELR-LELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 239 RNKERAQYyLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKyieefqraqdfwRQKK 318
Cdd:COG1196   290 EYELLAEL-ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE------------LEEA 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 319 REEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLmKQLEETLRQRDDLEQvRQELYQEEQAEiIKLKVKEE 398
Cdd:COG1196   357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA-AQLEELEEAEEALLE-RLERLEEELEE-LEEALAEL 433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 399 AELRLRRQREMKQDFEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRmkqlehkRAVEKLIEERRSQF 478
Cdd:COG1196   434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR-------LLLLLEAEADYEGF 506

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1907195237 479 LADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHAA 516
Cdd:COG1196   507 LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL 544
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 72-376 7.25e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 58.60  E-value: 7.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  72 KHQKLVDEKfrkslniQVMNKLERQAKNQVVQNENDEKVERQRFLRVLQNE---QFELDMEEAI-QKAEANKMLRDRQLE 147
Cdd:pfam17380 279 QHQKAVSER-------QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEkarQAEMDRQAAIyAEQERMAMERERELE 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 148 ----QEERLANELARLKHESLKDKKMRQ-------QVRENSIELRELEQKLKAAYMNKERAAQIVEKdamKYEQMKRDAE 216
Cdd:pfam17380 352 rirqEERKRELERIRQEEIAMEISRMRElerlqmeRQQKNERVRQELEAARKVKILEEERQRKIQQQ---KVEMEQIRAE 428

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 217 IERIMMEEHDRLLKEESAKQERRNKERA--QYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKL 294
Cdd:pfam17380 429 QEEARQREVRRLEEERAREMERVRLEEQerQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 295 ----EKKNAIQKYIEEFQRAqdFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLR 370
Cdd:pfam17380 509 ieeeRKRKLLEKEMEERQKA--IYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEK 586


                  ....*.
gi 1907195237 371 QRDDLE 376
Cdd:pfam17380 587 ARAEYE 592
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 71-401 1.63e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  71 EKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRfLRVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEE 150
Cdd:COG1196   213 ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELE-ELEAELAELEAELEELRLELEELELELEEAQAEEY 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 151 RLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAaymnkeraaqivekdamkyEQMKRDAEIERIMMEEHDRLLK 230
Cdd:COG1196   292 ELLAELARLEQDIARLEERRRELEERLEELEEELAELEE-------------------ELEELEEELEELEEELEEAEEE 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 231 EESAKQERRNKERAQyyLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRA 310
Cdd:COG1196   353 LEEAEAELAEAEEAL--LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 311 QDFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEI 390
Cdd:COG1196   431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510

                         330
                  ....*....|.
gi 1907195237 391 IKLKVKEEAEL 401
Cdd:COG1196   511 KAALLLAGLRG 521
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 160-461 2.35e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 57.06  E-value: 2.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 160 KHESLKDKKMRQQVREnsiELRELEQKLKAAYMNKERAAQIVEKDAMKYEQ----MKRDAEIERIMMEEHDRLLKEESAK 235
Cdd:pfam17380 292 KFEKMEQERLRQEKEE---KAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKRELERIRQE 368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 236 QERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAiqkyieefqraqdfwR 315
Cdd:pfam17380 369 EIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEA---------------R 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 316 QKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQnllmKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKV 395
Cdd:pfam17380 434 QREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKK----LELEKEKRDRKRAEEQRRKILEKELEERKQAMI 509

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907195237 396 KEEAELRL------RRQREMKQDFEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQL 461
Cdd:pfam17380 510 EEERKRKLlekemeERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQI 581
PTZ00121 PTZ00121
MAEBL; Provisional
 56-506 3.94e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 3.94e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237   56 KPTEMATKKRALSFSEKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRFLRvlQNEQFELDMEEAIQKA 135
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK--KAEEDKKKADELKKAA 1414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  136 EANKMLRDRQLEQEERLANELARLKHEslkDKKMRQQVRENSIELRELEQ-KLKAAYMNKERAAQIVEKDAMKYEQMKRD 214
Cdd:PTZ00121  1415 AAKKKADEAKKKAEEKKKADEAKKKAE---EAKKADEAKKKAEEAKKAEEaKKKAEEAKKADEAKKKAEEAKKADEAKKK 1491

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  215 AEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLK-EKLMIDEIVRKIYEEDQVERQQK 293
Cdd:PTZ00121  1492 AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKaDELKKAEELKKAEEKKKAEEAKK 1571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  294 LEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQrd 373
Cdd:PTZ00121  1572 AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKA-- 1649

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  374 dlEQVRQElyqEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMALKELILQAA-----------KEEEETFKKAMLAKF 442
Cdd:PTZ00121  1650 --EELKKA---EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAeeakkaeelkkKEAEEKKKAEELKKA 1724

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907195237  443 AEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQGCINEIIEEE 506
Cdd:PTZ00121  1725 EEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEE 1788
PTZ00121 PTZ00121
MAEBL; Provisional
 105-550 1.78e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 1.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  105 ENDEKVERQRFLRVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEERLANElARLKHESLKDKKMRQQVRENSIELRELE 184
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE-ARMAHFARRQAAIKAEEARKADELKKAE 1287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  185 QKLKAAYMNKERAAQIVE------KDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYyldlEKQLEDQE 258
Cdd:PTZ00121  1288 EKKKADEAKKAEEKKKADeakkkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAA----ADEAEAAE 1363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  259 RRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKleKKNAIQKYIEEFQRAQDfwRQKKREEMEEENRKIIEFANIQEQ 338
Cdd:PTZ00121  1364 EKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK--KAEEDKKKADELKKAAA--AKKKADEAKKKAEEKKKADEAKKK 1439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  339 REGERMARVHEIEEKRVQRQNLLMKQLEETlRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMA 418
Cdd:PTZ00121  1440 AEEAKKADEAKKKAEEAKKAEEAKKKAEEA-KKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA 1518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  419 LKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEelQLQQRRQGC 498
Cdd:PTZ00121  1519 EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK--KAEEARIEE 1596

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907195237  499 INEIIEEERLRLLKEhaakllgylpkgvFKREDDVDMLGEEFRKAYQKRDGV 550
Cdd:PTZ00121  1597 VMKLYEEEKKMKAEE-------------AKKAEEAKIKAEELKKAEEEKKKV 1635
PTZ00121 PTZ00121
MAEBL; Provisional
 56-418 6.74e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.74e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237   56 KPTEMATKKRALSFSEKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRFLRVLQN--EQFELDMEEAIQ 133
Cdd:PTZ00121  1425 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKkaEEAKKKADEAKK 1504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  134 KAEANKMLRDRQLEQEERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKD---AMKYEQ 210
Cdd:PTZ00121  1505 AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknmALRKAE 1584

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  211 MKRDAEIERI----MMEEHDRLLKEESAKQERRNKERAQyyldlEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEED 286
Cdd:PTZ00121  1585 EAKKAEEARIeevmKLYEEEKKMKAEEAKKAEEAKIKAE-----ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEEN 1659

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  287 QVERQQKLEKKNAIQKYIEEFQRAQDFWRQ------------------KKREEMEEENRKIIEFANIQEQREGERMARVH 348
Cdd:PTZ00121  1660 KIKAAEEAKKAEEDKKKAEEAKKAEEDEKKaaealkkeaeeakkaeelKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA 1739

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  349 EiEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMA 418
Cdd:PTZ00121  1740 E-EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFA 1808
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 252-517 1.30e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 51.28  E-value: 1.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 252 KQLEDQERRKQEAYEQLLKEKLMIDEIVRKIyEEDQVERQQKLEKKNAIqkYIEEFQRAQDFWRQKKREEMEEENRkiiE 331
Cdd:pfam17380 288 QQQEKFEKMEQERLRQEKEEKAREVERRRKL-EEAEKARQAEMDRQAAI--YAEQERMAMERERELERIRQEERKR---E 361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 332 FANIQEQREGERMARVHEIEEKRVQRQ--NLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEA-------ELR 402
Cdd:pfam17380 362 LERIRQEEIAMEISRMRELERLQMERQqkNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEarqrevrRLE 441

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 403 LRRQREMKQDFEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIElmnAQKQRMKQLEhkravEKLIEERRSQFLADK 482
Cdd:pfam17380 442 EERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKR---AEEQRRKILE-----KELEERKQAMIEEER 513

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1907195237 483 QRELEELQLQQRRqgciNEIIEEERLRLLKEHAAK 517
Cdd:pfam17380 514 KRKLLEKEMEERQ----KAIYEEERRREAEEERRK 544
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 165-489 1.37e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  165 KDKKMRQQVRENSIELRELEQKLKAA---YMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNK 241
Cdd:TIGR02168  664 GSAKTNSSILERRREIEELEEKIEELeekIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  242 ERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQK---------LEKKNAIQKYIEEFQRAQD 312
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKeelkalreaLDELRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  313 FWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLmKQLEETLRQRDDLEQVRQELYQEEQAEIIK 392
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-SELEALLNERASLEEALALLRSELEELSEE 902

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  393 LKVKEEAELRLRRQREMKQDFEDQMALKeliLQAAKEEEETFkkamLAKFAEDDRIELMNAqkqrmkqLEHKRAVEKLIE 472
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELR---LEGLEVRIDNL----QERLSEEYSLTLEEA-------EALENKIEDDEE 968

                          330
                   ....*....|....*..
gi 1907195237  473 ERRsQFLADKQRELEEL 489
Cdd:TIGR02168  969 EAR-RRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 236-522 1.40e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.48  E-value: 1.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 236 QERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQdfwr 315
Cdd:COG1196   219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL---- 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 316 qKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKV 395
Cdd:COG1196   295 -AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 396 KEEAELRLRRQREMKQDFEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERR 475
Cdd:COG1196   374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1907195237 476 sqfLADKQRELEELQLQQRRQgcINEIIEEERLRLLKEHAAKLLGYL 522
Cdd:COG1196   454 ---LEEEEEALLELLAELLEE--AALLEAALAELLEELAEAAARLLL 495
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 250-513 1.60e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 1.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 250 LEKQLED--QERRKQEAYeQLLKEKLMIDEIVRKIYEEDQVERQQKL--EKKNAIQKYIEEFQRAQDFW---RQKKREEM 322
Cdd:COG1196   198 LERQLEPleRQAEKAERY-RELKEELKELEAELLLLKLRELEAELEEleAELEELEAELEELEAELAELeaeLEELRLEL 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 323 EEENRKIIEfANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEE--AE 400
Cdd:COG1196   277 EELELELEE-AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEelEE 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 401 LRLRRQREMKQDFEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLA 480
Cdd:COG1196   356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1907195237 481 DKQRELEELQLQQRRQGCINEIIEEERLRLLKE 513
Cdd:COG1196   436 EEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468
PRK12704 PRK12704
phosphodiesterase; Provisional
 184-353 3.20e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 46.69  E-value: 3.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 184 EQKLKAAymnKERAAQIVEKDAMKYEQMKRDAEIEriMMEEHDRLLKEesakQERRNKERAQYYLDLEKQLEDQE---RR 260
Cdd:PRK12704   30 EAKIKEA---EEEAKRILEEAKKEAEAIKKEALLE--AKEEIHKLRNE----FEKELRERRNELQKLEKRLLQKEenlDR 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 261 KQEAYEQllKEKLMIDEIVRKIYEEDQVERQQKlEKKNAIQKYIEEFQRAQDFwrqkkreeMEEENRKIIeFANIQEQRE 340
Cdd:PRK12704  101 KLELLEK--REEELEKKEKELEQKQQELEKKEE-ELEELIEEQLQELERISGL--------TAEEAKEIL-LEKVEEEAR 168

                         170
                  ....*....|...
gi 1907195237 341 GERMARVHEIEEK 353
Cdd:PRK12704  169 HEAAVLIKEIEEE 181
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 91-488 7.48e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 7.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  91 NKLERQAKNQVVQNENDEKVERQRFLRVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDKKMR 170
Cdd:COG1196   400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 171 QQVRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDL 250
Cdd:COG1196   480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVA 559

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 251 EKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKII 330
Cdd:COG1196   560 AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 331 EFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMK 410
Cdd:COG1196   640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 411 QDFEDQMALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKL-------IEE-----RRSQF 478
Cdd:COG1196   720 ELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaIEEyeeleERYDF 799

                         410
                  ....*....|
gi 1907195237 479 LADKQRELEE 488
Cdd:COG1196   800 LSEQREDLEE 809
PTZ00121 PTZ00121
MAEBL; Provisional
 99-547 1.11e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237   99 NQVVQNENDEKVERQRFLRVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDKKMRQQVRENSI 178
Cdd:PTZ00121  1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  179 ELRELEQKLKAAYMNKERAAQIVE-----------------KDAMKYEQMKRDAE---------IERIMMEEHDRLLKEE 232
Cdd:PTZ00121  1162 DARKAEEARKAEDAKKAEAARKAEevrkaeelrkaedarkaEAARKAEEERKAEEarkaedakkAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  233 SAKQER-RNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLE--KKNAIQKYIEEFQR 309
Cdd:PTZ00121  1242 AKKAEEeRNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADeaKKKAEEAKKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  310 AQDFWRQKKREEME---EENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQLEETLRQRddlEQVRQELYQEE 386
Cdd:PTZ00121  1322 KKAEEAKKKADAAKkkaEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKK 1398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  387 QAEIIKLKVKE--EAELRLRRQREMKQDFEDQMALKELILQA--AKEEEETFKKAMLAKFAEDDRI---ELMNAQKQRMK 459
Cdd:PTZ00121  1399 KAEEDKKKADElkKAAAAKKKADEAKKKAEEKKKADEAKKKAeeAKKADEAKKKAEEAKKAEEAKKkaeEAKKADEAKKK 1478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  460 QLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQGCINEIIEEERLRllKEHAAKLLGYLPKGVFKREDDVDMLGEE 539
Cdd:PTZ00121  1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK--KAEEAKKADEAKKAEEKKKADELKKAEE 1556


                   ....*...
gi 1907195237  540 FRKAYQKR 547
Cdd:PTZ00121  1557 LKKAEEKK 1564
PTZ00121 PTZ00121
MAEBL; Provisional
 92-334 2.02e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 2.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237   92 KLERQAKNQVVQNENDEKVERQRFLRVLQNEQFELDM--EEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDK-- 167
Cdd:PTZ00121  1571 KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMkaEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKae 1650

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  168 KMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEiERIMMEEHDRLLKEESAKQERRNKERAQYY 247
Cdd:PTZ00121  1651 ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE-EAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  248 LDLEKQLEDQERRKQEAyEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENR 327
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKA-EEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFA 1808


                   ....*..
gi 1907195237  328 KIIEFAN 334
Cdd:PTZ00121  1809 NIIEGGK 1815
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 75-382 3.44e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 3.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237   75 KLVDEKFRKSLNIQVMNKLERQAKNQVVQNEndEKVERQRFLRVLQNEQFELDMEEAIQKAEANKMLRDRQLEQEERLAN 154
Cdd:TIGR02168  716 QLRKELEELSRQISALRKDLARLEAEVEQLE--ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  155 ELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEI-----------ERIMME 223
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlaaeieeleelIEELES 873

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  224 EHDRLLKEESAKQERRNKERAQYYlDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIyEEDQVERQQKLEKKNAIQK- 302
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELE-ELSEELRELESKRSELRRELEELREKLAQLELRL-EGLEVRIDNLQERLSEEYSl 951

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  303 ---YIEEFQRAQDFWRQKKREEMEEENRKIIEFANIQeqregerMARVHEIEEKRvQRQNLLMKQLEETLRQRDDLEQVR 379
Cdd:TIGR02168  952 tleEAEALENKIEDDEEEARRRLKRLENKIKELGPVN-------LAAIEEYEELK-ERYDFLTAQKEDLTEAKETLEEAI 1023


                   ...
gi 1907195237  380 QEL 382
Cdd:TIGR02168 1024 EEI 1026
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 125-246 5.56e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.89  E-value: 5.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237 125 ELDMEEAIQKAEANKMLRDRQLEQEERLANELARLkHESLKDKKMRQQVRENSIeLRELEQKLKAAYMNKERAAQIVEKD 204
Cdd:PRK00409  515 KEKLNELIASLEELERELEQKAEEAEALLKEAEKL-KEELEEKKEKLQEEEDKL-LEEAEKEAQQAIKEAKKEADEIIKE 592

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1907195237 205 AMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQY 246
Cdd:PRK00409  593 LRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQ 634
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 121-516 6.61e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 6.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  121 NEQFELDMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDKKMRQQVRENSIELRELEQKLKAAymnKERAAQI 200
Cdd:pfam02463  637 LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ---REKEELK 713

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  201 VEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVR 280
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE 793

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  281 KIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNL 360
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELL 873

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  361 LMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQdfedQMALKELILQAAKEEEETFKKAMLA 440
Cdd:pfam02463  874 LKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIK----EEAEILLKYEEEPEELLLEEADEKE 949

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907195237  441 KFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHAA 516
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLEL 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 216-492 8.65e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 8.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  216 EIERIMMEEHDRLLKEesaKQERRNKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKL- 294
Cdd:TIGR02169  204 RREREKAERYQALLKE---KREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKk 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  295 ------EKKNAIQKYIEEFQ----RAQDFWRQKKREEMEEENRKIIEFANIQEQREgERMARVHEIEEKRVQRQNlLMKQ 364
Cdd:TIGR02169  281 ikdlgeEEQLRVKEKIGELEaeiaSLERSIAEKERELEDAEERLAKLEAEIDKLLA-EIEELEREIEEERKRRDK-LTEE 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  365 LEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMALKELILQAAKEEEETFKKAMLAKFAE 444
Cdd:TIGR02169  359 YAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE 438

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907195237  445 -----DDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFLADKQRELEELQLQ 492
Cdd:TIGR02169  439 leeekEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 144-473 1.73e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.21  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  144 RQLEQEERLANELARLKHE--SLKDKKMRQQ--VRENSIELRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIER 219
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRElsSLQSELRRIEnrLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  220 IMMEEHDRLLKEESAKQERRNKERAQYYLDLEK--------QLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQV--- 288
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEkey 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  289 ---ERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQNLLMKQL 365
Cdd:TIGR02169  831 lekEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA 910

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  366 E-ETLRQRDDLEQVRQELYQEEQAEIIKLKVKE----EAELRLRRQREMKQDFEDQM-ALKELILQAAKEEEETfkkaml 439
Cdd:TIGR02169  911 QiEKKRKRLSELKAKLEALEEELSEIEDPKGEDeeipEEELSLEDVQAELQRVEEEIrALEPVNMLAIQEYEEV------ 984

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1907195237  440 akfaEDDRIELmnaQKQRMKQLEHKRAVEKLIEE 473
Cdd:TIGR02169  985 ----LKRLDEL---KEKRAKLEEERKAILERIEE 1011
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 278-517 2.99e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.44  E-value: 2.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  278 IVRKIYEEDQVER-QQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQ 356
Cdd:TIGR02169  666 ILFSRSEPAELQRlRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  357 RQNL-------------LMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQR------EMKQDFEDQM 417
Cdd:TIGR02169  746 LSSLeqeienvkselkeLEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRiearlrEIEQKLNRLT 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  418 ALKELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMK-QLEHKRAVEKLIEERRSQFLADKQRELEELQLQQRRQ 496
Cdd:TIGR02169  826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          250       260
                   ....*....|....*....|.
gi 1907195237  497 GCINEIIEEERLRLLKEHAAK 517
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKL 926
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 185-432 7.53e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 7.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  185 QKLKAAYMNKERAAQIVEKDAM--KYEQMKRDAEIERIMMEEHDRLLKEESAKQERRNKERAQyyldLEKQLEDQERRKQ 262
Cdd:TIGR02168  216 KELKAELRELELALLVLRLEELreELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE----LEEEIEELQKELY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  263 EAYE---------QLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNAIQKYIEEFQRAQDFWRQKKREEMEEENRKIIEFA 333
Cdd:TIGR02168  292 ALANeisrleqqkQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195237  334 NIQEQREGERMARVHEIEEKRvQRQNLLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDF 413
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLE-LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          250
                   ....*....|....*....
gi 1907195237  414 EDQMALKELILQAAKEEEE 432
Cdd:TIGR02168  451 ELQEELERLEEALEELREE 469
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH