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Conserved domains on  [gi|1889031752|ref|XP_035642945|]
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GPI mannosyltransferase 3 isoform X1 [Oncorhynchus keta]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229536)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PMT_2 super family cl21590
Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are ...
 42-521 8.90e-109

Dolichyl-phosphate-mannose-protein mannosyltransferase; This family contains members that are not captured by pfam02366.


The actual alignment was detected with superfamily member PLN02816:

Pssm-ID: 473917  Cd Length: 546  Bit Score: 334.70  E-value: 8.90e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752  42 VTVFTVAFRLINCFLVQTSFVPDEYWQSLEIAHLMVFDYGYLTWEWTAGIRGFSYPLFFAAIYKILHFFTYDAVQLLVWL 121
Cdd:PLN02816   41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 122 PRVVQALLSALADIKLYCLIQSLEHSDVAKWTYLCQLCSWFTWYCCTRTLTNTMETTLTTLALYYYPlpgSKTHSSTKY- 200
Cdd:PLN02816  121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWP---CIRDSSIDYp 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 201 ------LILVALAVIVRPTALIVWLPLLVYHFWQEDNKLKLITHLCLPIGALTLGISTLIDCIFYGKWTLVQYNFLKFNV 274
Cdd:PLN02816  198 vnrkwgLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNF 277

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 275 FHNVAEFYGSHPWHWYFTQGFVVVIGPHLPFFLYGcTLASKRYRIMLItIVWTVMVYSCLAHKEFRFIYPVLPFCMVFCG 354
Cdd:PLN02816  278 LSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAG-IIKSKNQKLSAL-ILWVLAIYSILGHKEFRFVLPVLPIALIFSG 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 355 IALV----------------------NLRTWR---RPAACALLVSNLVPALYTGLLHQRGTLDVMGHLQTlcddrDPSTP 409
Cdd:PLN02816  356 YAFAqmevsgssssssvtkkkqvprqNHTKWSpklRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSD-----EAYKG 430

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 410 PLPEVLFLMPCHSTPFYSHIHCPMKMRFLECPPdlTGDKRYVDEAERFFADPHHWLRTSFPYKSMLPTHLVFFDVLEMEL 489
Cdd:PLN02816  431 RVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDESDQFLVNPLGFASELARNWSEPPSHIVLFASEETKL 508

                         490       500       510
                  ....*....|....*....|....*....|...
gi 1889031752 490 SAFLDRNRFMRSREIFHTHVPEGR-VGKSVLVY 521
Cdd:PLN02816  509 RDFMIQHSFKEVRRFFHAHFKVDRdLQSSVVVY 541
 
Name Accession Description Interval E-value
PLN02816 PLN02816
mannosyltransferase
 42-521 8.90e-109

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 334.70  E-value: 8.90e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752  42 VTVFTVAFRLINCFLVQTSFVPDEYWQSLEIAHLMVFDYGYLTWEWTAGIRGFSYPLFFAAIYKILHFFTYDAVQLLVWL 121
Cdd:PLN02816   41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 122 PRVVQALLSALADIKLYCLIQSLEHSDVAKWTYLCQLCSWFTWYCCTRTLTNTMETTLTTLALYYYPlpgSKTHSSTKY- 200
Cdd:PLN02816  121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWP---CIRDSSIDYp 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 201 ------LILVALAVIVRPTALIVWLPLLVYHFWQEDNKLKLITHLCLPIGALTLGISTLIDCIFYGKWTLVQYNFLKFNV 274
Cdd:PLN02816  198 vnrkwgLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNF 277

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 275 FHNVAEFYGSHPWHWYFTQGFVVVIGPHLPFFLYGcTLASKRYRIMLItIVWTVMVYSCLAHKEFRFIYPVLPFCMVFCG 354
Cdd:PLN02816  278 LSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAG-IIKSKNQKLSAL-ILWVLAIYSILGHKEFRFVLPVLPIALIFSG 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 355 IALV----------------------NLRTWR---RPAACALLVSNLVPALYTGLLHQRGTLDVMGHLQTlcddrDPSTP 409
Cdd:PLN02816  356 YAFAqmevsgssssssvtkkkqvprqNHTKWSpklRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSD-----EAYKG 430

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 410 PLPEVLFLMPCHSTPFYSHIHCPMKMRFLECPPdlTGDKRYVDEAERFFADPHHWLRTSFPYKSMLPTHLVFFDVLEMEL 489
Cdd:PLN02816  431 RVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDESDQFLVNPLGFASELARNWSEPPSHIVLFASEETKL 508

                         490       500       510
                  ....*....|....*....|....*....|...
gi 1889031752 490 SAFLDRNRFMRSREIFHTHVPEGR-VGKSVLVY 521
Cdd:PLN02816  509 RDFMIQHSFKEVRRFFHAHFKVDRdLQSSVVVY 541
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 45-430 7.87e-97

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 299.66  E-value: 7.87e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752  45 FTVAFRLINCFLVQTSfVPDEYWQSLEIAHLMVFDYGYLTWEWTA--GIRGFSYPLFFAAIYKILHFFTYDAVQLLVWLP 122
Cdd:pfam03901   5 LLLALRLLLALLVQTS-DPDEHFQSWEPLHYLIFGYGFLTWEWSPkyGIRSYLYPLLFALPYYLLARLFGDSKYLVFYAP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 123 RVVQALLSALADIKLYCLIQSLEHSDVAKWTYLCQLCSWFTWYCCTRTLTNTMETTLTTLALYYYPLPGSKTHSSTKY-- 200
Cdd:pfam03901  84 RLLLGLFSALCDYYLYRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTSVSNYKYlk 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 201 --LILVALAVIVRPTALIVWLPLLVYHFWQEDNK-----LKLITHLCLPIGALTLGISTLIDCIFYGKWTLVQYNFLKFN 273
Cdd:pfam03901 164 avLLIAALAILGRPTSALLWLPLVLYLLLRLRGKrlklfLFLAISLGLLVALLVLGAVILIDSYFYGRFVFTPLNFLKYN 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 274 VFHNVAEFYGSHPWHWYFTQGFVVVIGPHLPFFLYGCTLASKRYR----IMLITIVWTVMVYSCLAHKEFRFIYPVLPFC 349
Cdd:pfam03901 244 VLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLRKVsrlsQLLAPILIWLFIYSLQPHKEERFLYPVYPLI 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 350 MVFCGIALVNL--RTWRRPAACAL----LVSNLVPALYTGLLHQRGTL----DVMGHLQTLCDDRDPSTPPLPEVLFLMP 419
Cdd:pfam03901 324 LLSAAIALTRLsrRSWKVRKKLSLlfllLFFNVSLARLFGLVHQYGAPlavyDVMSFLNETPRENRNPAGPPVNVCIGME 403

                         410
                  ....*....|.
gi 1889031752 420 CHSTPFYSHIH 430
Cdd:pfam03901 404 CYSTPSSFFLH 414
 
Name Accession Description Interval E-value
PLN02816 PLN02816
mannosyltransferase
 42-521 8.90e-109

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 334.70  E-value: 8.90e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752  42 VTVFTVAFRLINCFLVQTSFVPDEYWQSLEIAHLMVFDYGYLTWEWTAGIRGFSYPLFFAAIYKILHFFTYDAVQLLVWL 121
Cdd:PLN02816   41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 122 PRVVQALLSALADIKLYCLIQSLEHSDVAKWTYLCQLCSWFTWYCCTRTLTNTMETTLTTLALYYYPlpgSKTHSSTKY- 200
Cdd:PLN02816  121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWP---CIRDSSIDYp 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 201 ------LILVALAVIVRPTALIVWLPLLVYHFWQEDNKLKLITHLCLPIGALTLGISTLIDCIFYGKWTLVQYNFLKFNV 274
Cdd:PLN02816  198 vnrkwgLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNF 277

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 275 FHNVAEFYGSHPWHWYFTQGFVVVIGPHLPFFLYGcTLASKRYRIMLItIVWTVMVYSCLAHKEFRFIYPVLPFCMVFCG 354
Cdd:PLN02816  278 LSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAG-IIKSKNQKLSAL-ILWVLAIYSILGHKEFRFVLPVLPIALIFSG 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 355 IALV----------------------NLRTWR---RPAACALLVSNLVPALYTGLLHQRGTLDVMGHLQTlcddrDPSTP 409
Cdd:PLN02816  356 YAFAqmevsgssssssvtkkkqvprqNHTKWSpklRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSD-----EAYKG 430

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 410 PLPEVLFLMPCHSTPFYSHIHCPMKMRFLECPPdlTGDKRYVDEAERFFADPHHWLRTSFPYKSMLPTHLVFFDVLEMEL 489
Cdd:PLN02816  431 RVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDESDQFLVNPLGFASELARNWSEPPSHIVLFASEETKL 508

                         490       500       510
                  ....*....|....*....|....*....|...
gi 1889031752 490 SAFLDRNRFMRSREIFHTHVPEGR-VGKSVLVY 521
Cdd:PLN02816  509 RDFMIQHSFKEVRRFFHAHFKVDRdLQSSVVVY 541
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
 45-430 7.87e-97

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 299.66  E-value: 7.87e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752  45 FTVAFRLINCFLVQTSfVPDEYWQSLEIAHLMVFDYGYLTWEWTA--GIRGFSYPLFFAAIYKILHFFTYDAVQLLVWLP 122
Cdd:pfam03901   5 LLLALRLLLALLVQTS-DPDEHFQSWEPLHYLIFGYGFLTWEWSPkyGIRSYLYPLLFALPYYLLARLFGDSKYLVFYAP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 123 RVVQALLSALADIKLYCLIQSLEHSDVAKWTYLCQLCSWFTWYCCTRTLTNTMETTLTTLALYYYPLPGSKTHSSTKY-- 200
Cdd:pfam03901  84 RLLLGLFSALCDYYLYRAVCRKYGLEIARWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLLEYGNTSVSNYKYlk 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 201 --LILVALAVIVRPTALIVWLPLLVYHFWQEDNK-----LKLITHLCLPIGALTLGISTLIDCIFYGKWTLVQYNFLKFN 273
Cdd:pfam03901 164 avLLIAALAILGRPTSALLWLPLVLYLLLRLRGKrlklfLFLAISLGLLVALLVLGAVILIDSYFYGRFVFTPLNFLKYN 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 274 VFHNVAEFYGSHPWHWYFTQGFVVVIGPHLPFFLYGCTLASKRYR----IMLITIVWTVMVYSCLAHKEFRFIYPVLPFC 349
Cdd:pfam03901 244 VLSNGSSFYGTHPWYFYFSNGLPNILGPFLLAFILGPLVLLLRKVsrlsQLLAPILIWLFIYSLQPHKEERFLYPVYPLI 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889031752 350 MVFCGIALVNL--RTWRRPAACAL----LVSNLVPALYTGLLHQRGTL----DVMGHLQTLCDDRDPSTPPLPEVLFLMP 419
Cdd:pfam03901 324 LLSAAIALTRLsrRSWKVRKKLSLlfllLFFNVSLARLFGLVHQYGAPlavyDVMSFLNETPRENRNPAGPPVNVCIGME 403

                         410
                  ....*....|.
gi 1889031752 420 CHSTPFYSHIH 430
Cdd:pfam03901 404 CYSTPSSFFLH 414
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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