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Conserved domains on  [gi|1842254856|ref|XP_034405622|]
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alpha-1,2-mannosyltransferase ALG9 isoform X2 [Cyclopterus lumpus]

Protein Classification

Glyco_transf_22 domain-containing protein( domain architecture ID 10511211)

Glyco_transf_22 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
1-392 2.92e-103

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


:

Pssm-ID: 281842  Cd Length: 414  Bit Score: 315.84  E-value: 2.92e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856   1 MHYLLYGTGMQTWEYSPLYAIRSYAYLWLHALPACLHAHVLQTNKVLVFYFVRCVLAFSCCVCELYFYKAVCKKFGLHVG 80
Cdd:pfam03901  32 LHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGDSKYLVFYAPRLLLGLFSALCDYYLYRAVCRKYGLEIA 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856  81 RLMLAFLVLSTGMFCSSAAFLPSSFCMYTTLVAMTGW--------FQDSTSLAVMGVAAGAIVGWPFSALVGIPIAFDLL 152
Cdd:pfam03901 112 RWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLleygntsvSNYKYLKAVLLIAALAILGRPTSALLWLPLVLYLL 191
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 153 VL--KRQWKGF--ITWSAVALLLLLVPLVA--VDSYFYGKLVIAPLNILLYNVFTpHGPDLYGTEPWHFYFSNGILNFNL 226
Cdd:pfam03901 192 LRlrGKRLKLFlfLAISLGLLVALLVLGAVilIDSYFYGRFVFTPLNFLKYNVLS-NGSSFYGTHPWYFYFSNGLPNILG 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 227 VFALALLSLPLtalmetLLHRFNVQNLgrpyWLTLSPMYLWMLVFFTRPHKEERFLFPIYPLICLSGAVALSSLQkcyhf 306
Cdd:pfam03901 271 PFLLAFILGPL------VLLLRKVSRL----SQLLAPILIWLFIYSLQPHKEERFLYPVYPLILLSAAIALTRLS----- 335
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 307 lfQRYRLEHYTVSSNWLalstvVVFSVLSLSRSVALFKGYHAPLDLYPEFHRIAKDPTLHSVPEGRPVIVCVGKEWHRFP 386
Cdd:pfam03901 336 --RRSWKVRKKLSLLFL-----LLFFNVSLARLFGLVHQYGAPLAVYDVMSFLNETPRENRNPAGPPVNVCIGMECYSTP 408

                  ....*.
gi 1842254856 387 SSFLLP 392
Cdd:pfam03901 409 SSFFLH 414
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
1-392 2.92e-103

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 315.84  E-value: 2.92e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856   1 MHYLLYGTGMQTWEYSPLYAIRSYAYLWLHALPACLHAHVLQTNKVLVFYFVRCVLAFSCCVCELYFYKAVCKKFGLHVG 80
Cdd:pfam03901  32 LHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGDSKYLVFYAPRLLLGLFSALCDYYLYRAVCRKYGLEIA 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856  81 RLMLAFLVLSTGMFCSSAAFLPSSFCMYTTLVAMTGW--------FQDSTSLAVMGVAAGAIVGWPFSALVGIPIAFDLL 152
Cdd:pfam03901 112 RWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLleygntsvSNYKYLKAVLLIAALAILGRPTSALLWLPLVLYLL 191
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 153 VL--KRQWKGF--ITWSAVALLLLLVPLVA--VDSYFYGKLVIAPLNILLYNVFTpHGPDLYGTEPWHFYFSNGILNFNL 226
Cdd:pfam03901 192 LRlrGKRLKLFlfLAISLGLLVALLVLGAVilIDSYFYGRFVFTPLNFLKYNVLS-NGSSFYGTHPWYFYFSNGLPNILG 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 227 VFALALLSLPLtalmetLLHRFNVQNLgrpyWLTLSPMYLWMLVFFTRPHKEERFLFPIYPLICLSGAVALSSLQkcyhf 306
Cdd:pfam03901 271 PFLLAFILGPL------VLLLRKVSRL----SQLLAPILIWLFIYSLQPHKEERFLYPVYPLILLSAAIALTRLS----- 335
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 307 lfQRYRLEHYTVSSNWLalstvVVFSVLSLSRSVALFKGYHAPLDLYPEFHRIAKDPTLHSVPEGRPVIVCVGKEWHRFP 386
Cdd:pfam03901 336 --RRSWKVRKKLSLLFL-----LLFFNVSLARLFGLVHQYGAPLAVYDVMSFLNETPRENRNPAGPPVNVCIGMECYSTP 408

                  ....*.
gi 1842254856 387 SSFLLP 392
Cdd:pfam03901 409 SSFFLH 414
PLN02816 PLN02816
mannosyltransferase
2-301 8.96e-11

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 64.28  E-value: 8.96e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856   2 HYLLYGTGMQTWEYSplYAIRSYaylwLHALPACLHAHVLQTNKVLVFYFV----RCVLAFSCCVCELYFYKAVCKKFGL 77
Cdd:PLN02816   73 HRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMikapRLMQSIFSAIGDLYLYKLSDALYGG 146
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856  78 HVGRLMLaFLVLSTGM--FCSSAAFlpsSFCMYTTLVAMTGWF-----QDSTSLAV-----MGVAAGAIVGWPFSALVGI 145
Cdd:PLN02816  147 NVATWSL-FCQMANWFifFCLNRTF---SNCLETVLTIMGLYYwpcirDSSIDYPVnrkwgLVIAALACAIRPTSAVIWL 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 146 PIA-FDLLVLKRQWKGFITWSAVALLLLLVPLVAVDSYFYGKLVIAPLNILLYNvFTPHGPDLYGTEPWHFYFSNGILNF 224
Cdd:PLN02816  223 YVGmLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFN-FLSSGGDYYGTHPWHWYFTQGFLVM 301
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1842254856 225 NLVFAlallslpltalmetllhRFNVQNLGRPYWLTLSPMYLWMLVFFT-RPHKEERFLFPIYPLICLSGAVALSSLQ 301
Cdd:PLN02816  302 LFTFT-----------------PFSIAGIIKSKNQKLSALILWVLAIYSiLGHKEFRFVLPVLPIALIFSGYAFAQME 362
 
Name Accession Description Interval E-value
Glyco_transf_22 pfam03901
Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. ...
1-392 2.92e-103

Alg9-like mannosyltransferase family; Members of this family are mannosyltransferase enzymes. At least some members are localized in endoplasmic reticulum and involved in GPI anchor biosynthesis.


Pssm-ID: 281842  Cd Length: 414  Bit Score: 315.84  E-value: 2.92e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856   1 MHYLLYGTGMQTWEYSPLYAIRSYAYLWLHALPACLHAHVLQTNKVLVFYFVRCVLAFSCCVCELYFYKAVCKKFGLHVG 80
Cdd:pfam03901  32 LHYLIFGYGFLTWEWSPKYGIRSYLYPLLFALPYYLLARLFGDSKYLVFYAPRLLLGLFSALCDYYLYRAVCRKYGLEIA 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856  81 RLMLAFLVLSTGMFCSSAAFLPSSFCMYTTLVAMTGW--------FQDSTSLAVMGVAAGAIVGWPFSALVGIPIAFDLL 152
Cdd:pfam03901 112 RWALLLSLTSWGMFFASTRTLPNSFEMILTSIALYYLleygntsvSNYKYLKAVLLIAALAILGRPTSALLWLPLVLYLL 191
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 153 VL--KRQWKGF--ITWSAVALLLLLVPLVA--VDSYFYGKLVIAPLNILLYNVFTpHGPDLYGTEPWHFYFSNGILNFNL 226
Cdd:pfam03901 192 LRlrGKRLKLFlfLAISLGLLVALLVLGAVilIDSYFYGRFVFTPLNFLKYNVLS-NGSSFYGTHPWYFYFSNGLPNILG 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 227 VFALALLSLPLtalmetLLHRFNVQNLgrpyWLTLSPMYLWMLVFFTRPHKEERFLFPIYPLICLSGAVALSSLQkcyhf 306
Cdd:pfam03901 271 PFLLAFILGPL------VLLLRKVSRL----SQLLAPILIWLFIYSLQPHKEERFLYPVYPLILLSAAIALTRLS----- 335
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 307 lfQRYRLEHYTVSSNWLalstvVVFSVLSLSRSVALFKGYHAPLDLYPEFHRIAKDPTLHSVPEGRPVIVCVGKEWHRFP 386
Cdd:pfam03901 336 --RRSWKVRKKLSLLFL-----LLFFNVSLARLFGLVHQYGAPLAVYDVMSFLNETPRENRNPAGPPVNVCIGMECYSTP 408

                  ....*.
gi 1842254856 387 SSFLLP 392
Cdd:pfam03901 409 SSFFLH 414
PLN02816 PLN02816
mannosyltransferase
2-301 8.96e-11

mannosyltransferase


Pssm-ID: 215437  Cd Length: 546  Bit Score: 64.28  E-value: 8.96e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856   2 HYLLYGTGMQTWEYSplYAIRSYaylwLHALPACLHAHVLQTNKVLVFYFV----RCVLAFSCCVCELYFYKAVCKKFGL 77
Cdd:PLN02816   73 HRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMikapRLMQSIFSAIGDLYLYKLSDALYGG 146
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856  78 HVGRLMLaFLVLSTGM--FCSSAAFlpsSFCMYTTLVAMTGWF-----QDSTSLAV-----MGVAAGAIVGWPFSALVGI 145
Cdd:PLN02816  147 NVATWSL-FCQMANWFifFCLNRTF---SNCLETVLTIMGLYYwpcirDSSIDYPVnrkwgLVIAALACAIRPTSAVIWL 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842254856 146 PIA-FDLLVLKRQWKGFITWSAVALLLLLVPLVAVDSYFYGKLVIAPLNILLYNvFTPHGPDLYGTEPWHFYFSNGILNF 224
Cdd:PLN02816  223 YVGmLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFN-FLSSGGDYYGTHPWHWYFTQGFLVM 301
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1842254856 225 NLVFAlallslpltalmetllhRFNVQNLGRPYWLTLSPMYLWMLVFFT-RPHKEERFLFPIYPLICLSGAVALSSLQ 301
Cdd:PLN02816  302 LFTFT-----------------PFSIAGIIKSKNQKLSALILWVLAIYSiLGHKEFRFVLPVLPIALIFSGYAFAQME 362
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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