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Conserved domains on  [gi|1835671658|ref|XP_033815845|]
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lysophospholipid acyltransferase 7 [Geotrypetes seraphini]

Protein Classification

membrane-bound O-acyltransferase family protein( domain architecture ID 326)

membrane-bound O-acyltransferase (MBOAT) family protein may be an integral transmembrane enzyme that modifies protective cell-surface polymers, catalyzing the transfer of an acetyl group from acetyl-CoA to its target substrates

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MBOAT super family cl00738
MBOAT, membrane-bound O-acyltransferase family; The MBOAT (membrane bound O-acyl transferase) ...
6-445 3.01e-38

MBOAT, membrane-bound O-acyltransferase family; The MBOAT (membrane bound O-acyl transferase) family of membrane proteins contains a variety of acyltransferase enzymes. A conserved histidine has been suggested to be the active site residue.


The actual alignment was detected with superfamily member PLN02332:

Pssm-ID: 445070  Cd Length: 465  Bit Score: 144.81  E-value: 3.01e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658   6 LTYLAILIFSIPIGFVFKS-KGPSVKQLGGAALGVLLILLTCHIHS-LHSLITILGTWLILKLTPRSCHFLVLSWTFIYL 83
Cdd:PLN02332   19 LRFLLCFVASIPLSALWRFiPSGTLRHLYAALSGAFLSYLSFGFSSnLHFVVPMIAGYLAMALARRRCGAITFLFAFAYL 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658  84 LFFRtVTYFrlppptpFANA----------VQLLLTLKMVSLANEVQEYYsAKRQDMSSFRKPAAIgviPRIPNLVETLC 153
Cdd:PLN02332   99 IYCH-VFYM-------SGDAwkeggidftgALMVLTLKVISCAMNYQDGL-LKEEGLREAQKKNRL---IQLPSLIEYLG 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 154 YSYCYMGLMTGPFYRYKTYHDWLQ-----------QPDSLYIPSWRPLLlrlrPAPVFGLLFFLVSYLFPLAYVQTDEFY 222
Cdd:PLN02332  167 YCLCCGSHLAGPVFEFRDYLDWTEgkglwdpnakgKCPSPYGATLRALL----QAAICMGLYLYLTPQFPLSRFTEPDYQ 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 223 ERPFLYRLFYMAPTFFVFRMRFYVAWIFAECGCIAAafgaypaaaksrpGGGPTvdytsaGRSPEGERLAidyDYETVKN 302
Cdd:PLN02332  243 EWGFWHRFGYQYMSGFTARWKYYFIWSISEAAIIIS-------------GLGFS------GWDGEGKPKA---KWDRAKN 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 303 IDCYGTDFCVKVKDGMRYWNMTVQWWLAQYIY-------KNAPLRSFIFrstwTMLISAYWHGIHPGYYLSFLTIPLCLA 375
Cdd:PLN02332  301 VDILGVELAKSAVQIPLVWNIQVSTWLRHYVYerlvpkgKKPGFFQLLA----TQTVSAVWHGLYPGYILFFVQSALMIA 376
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1835671658 376 AEGAMEVGLRHHLSSSGQLV--FDWVQWFLKMRAYDYMCMGFVLLTFSDTVRYWGSIYYCIHMLALGLMLVG 445
Cdd:PLN02332  377 GSRVIYRWQQAIPPSMALARnlLVFINFLYTVLVLNYSCVGFMLLSLDETLAAYGSVYYIGTIIPVVLILLG 448
 
Name Accession Description Interval E-value
PLN02332 PLN02332
membrane bound O-acyl transferase (MBOAT) family protein
6-445 3.01e-38

membrane bound O-acyl transferase (MBOAT) family protein


Pssm-ID: 215190  Cd Length: 465  Bit Score: 144.81  E-value: 3.01e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658   6 LTYLAILIFSIPIGFVFKS-KGPSVKQLGGAALGVLLILLTCHIHS-LHSLITILGTWLILKLTPRSCHFLVLSWTFIYL 83
Cdd:PLN02332   19 LRFLLCFVASIPLSALWRFiPSGTLRHLYAALSGAFLSYLSFGFSSnLHFVVPMIAGYLAMALARRRCGAITFLFAFAYL 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658  84 LFFRtVTYFrlppptpFANA----------VQLLLTLKMVSLANEVQEYYsAKRQDMSSFRKPAAIgviPRIPNLVETLC 153
Cdd:PLN02332   99 IYCH-VFYM-------SGDAwkeggidftgALMVLTLKVISCAMNYQDGL-LKEEGLREAQKKNRL---IQLPSLIEYLG 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 154 YSYCYMGLMTGPFYRYKTYHDWLQ-----------QPDSLYIPSWRPLLlrlrPAPVFGLLFFLVSYLFPLAYVQTDEFY 222
Cdd:PLN02332  167 YCLCCGSHLAGPVFEFRDYLDWTEgkglwdpnakgKCPSPYGATLRALL----QAAICMGLYLYLTPQFPLSRFTEPDYQ 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 223 ERPFLYRLFYMAPTFFVFRMRFYVAWIFAECGCIAAafgaypaaaksrpGGGPTvdytsaGRSPEGERLAidyDYETVKN 302
Cdd:PLN02332  243 EWGFWHRFGYQYMSGFTARWKYYFIWSISEAAIIIS-------------GLGFS------GWDGEGKPKA---KWDRAKN 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 303 IDCYGTDFCVKVKDGMRYWNMTVQWWLAQYIY-------KNAPLRSFIFrstwTMLISAYWHGIHPGYYLSFLTIPLCLA 375
Cdd:PLN02332  301 VDILGVELAKSAVQIPLVWNIQVSTWLRHYVYerlvpkgKKPGFFQLLA----TQTVSAVWHGLYPGYILFFVQSALMIA 376
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1835671658 376 AEGAMEVGLRHHLSSSGQLV--FDWVQWFLKMRAYDYMCMGFVLLTFSDTVRYWGSIYYCIHMLALGLMLVG 445
Cdd:PLN02332  377 GSRVIYRWQQAIPPSMALARnlLVFINFLYTVLVLNYSCVGFMLLSLDETLAAYGSVYYIGTIIPVVLILLG 448
COG5202 COG5202
Predicted membrane protein [Function unknown];
3-456 7.72e-35

Predicted membrane protein [Function unknown];


Pssm-ID: 227529  Cd Length: 512  Bit Score: 136.25  E-value: 7.72e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658   3 PDELTYLAILIFSIPIGFVFKS--KGPSVKQLGGAALGVLLILLTCHIHS--LHSLITILGTWLILKLTPRSCHFLVLSW 78
Cdd:COG5202    20 YLELRFLACLLLTLPFVSILKRnpTRIRTHNLFSISLILFYLFGVRHLVSgaYILASISLFTYLLRYFYRSAYMPTVLFI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658  79 TFIYLLF-FRTVTYFRLPPPTPF-ANAVQLLLTLKMVSLAnevQEYYSAK--RQDMSSFRKPAAIgviPRIPNLVETLCY 154
Cdd:COG5202   100 VILGHYKiFHAAQLFEERISTSFdITGSQMVLTMKLTSFA---WSYYDGKeySSDLTEHQKSRAR---RGTPTVLDFLSY 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 155 SYCYMGLMTGPFYRYKTYHDWLQQ------PDSLY-----IPSWRPLLLRLRPAPVFGLLFFLVSYLFPLAYVQTDEFYE 223
Cdd:COG5202   174 IFFIPGLLLGPAFDYADFDSWLTCemfrslMENPYerpkrPPNGKLALATFLKGLGWLILFQVGRISIPRKHLLEEDFPV 253
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 224 RPFLYRLFYMAPTFFVFRMRFYVAWIFAECGCIAAafgaypaaaksrpgggptvdytsaGRSPEGERLAIDYDYETVKNI 303
Cdd:COG5202   254 RLLPMRWAYLYLFTFGNRIKYYFAWHFSHGSCILF------------------------GLGYNGPDSTQKIRWDRVRNI 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 304 DCYGTDFCVKVKDGMRYWNMTVQWWLAQYIY-KNAPL-RSFIFRST-WTMLISAYWHGIHPGYYLSFLTiplcLAAEGAM 380
Cdd:COG5202   310 DFMKVELATNVKDLLEAWNMNTNKWLKNSVYlRVVKKgKKPGFWSTlGTFAISALWHGINPGYYLTFLS----LAASQTI 385
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 381 EVGLRHHLSS-------SGQLVFDWVQWFLKMRA----YDYMCMGFVLLTFSDTVRYWGSIYYCIHMlalgLMLVGHALA 449
Cdd:COG5202   386 VKENRRLLRPfflredgVTPLPSKSLYDVLGRIAmlllTTYFSASFFLLSLKDSMYVWRSVYFAVHI----FLAFSLAVF 461

                  ....*..
gi 1835671658 450 SGVTRSP 456
Cdd:COG5202   462 IAPIRKK 468
MBOAT pfam03062
MBOAT, membrane-bound O-acyltransferase family; The MBOAT (membrane bound O-acyl transferase) ...
122-380 2.29e-17

MBOAT, membrane-bound O-acyltransferase family; The MBOAT (membrane bound O-acyl transferase) family of membrane proteins contains a variety of acyltransferase enzymes. A conserved histidine has been suggested to be the active site residue.


Pssm-ID: 427117  Cd Length: 334  Bit Score: 82.87  E-value: 2.29e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 122 YYSAKRQDMSSFRKPAAIGVIPRIPNLVETLCYSYCYMGLMTGPFYRYKTYHDWLQQP----DSLYIPSWRPLLLRLRPA 197
Cdd:pfam03062  55 LLFSYRPVSLSFRKLASAAALSQDPSLLEYLGYVFFYPGLLVGPIFSYSDYMSFPRDPlfrwLYYVKRNLAPALGALFLG 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 198 PVFGLLFFLVSYLFPLAYVQTDEFYERPFLYRLFYMAPTFFVFRMRFYVAWIFAECgciaaafgayPAAAKSRPGGGPTV 277
Cdd:pfam03062 135 LTYLILIQYLLSHLPDKDFSKFKFLSYAFLLRFSVIMRILLGLLWLFLLIFDFLGW----------LFAEGEDILFGLGF 204
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 278 DYTSagrspegerlaidydyeTVKNIDCYGT-DFCVKVKDGMRYWNMTVQWWLAQYIYK---NAPLRSFIFRSTWTMLIS 353
Cdd:pfam03062 205 NGWD-----------------RVAPENIYRCwENAVSFSEFWRAWNIPVHKWLKRYVYKplgKKGKLNKFLATLATFLFS 267
                         250       260
                  ....*....|....*....|....*..
gi 1835671658 354 AYWHGIHPGYYLSFLTIPLCLAAEGAM 380
Cdd:pfam03062 268 AVWHGYYLGYLLWFVLRVLLLLAEKLI 294
 
Name Accession Description Interval E-value
PLN02332 PLN02332
membrane bound O-acyl transferase (MBOAT) family protein
6-445 3.01e-38

membrane bound O-acyl transferase (MBOAT) family protein


Pssm-ID: 215190  Cd Length: 465  Bit Score: 144.81  E-value: 3.01e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658   6 LTYLAILIFSIPIGFVFKS-KGPSVKQLGGAALGVLLILLTCHIHS-LHSLITILGTWLILKLTPRSCHFLVLSWTFIYL 83
Cdd:PLN02332   19 LRFLLCFVASIPLSALWRFiPSGTLRHLYAALSGAFLSYLSFGFSSnLHFVVPMIAGYLAMALARRRCGAITFLFAFAYL 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658  84 LFFRtVTYFrlppptpFANA----------VQLLLTLKMVSLANEVQEYYsAKRQDMSSFRKPAAIgviPRIPNLVETLC 153
Cdd:PLN02332   99 IYCH-VFYM-------SGDAwkeggidftgALMVLTLKVISCAMNYQDGL-LKEEGLREAQKKNRL---IQLPSLIEYLG 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 154 YSYCYMGLMTGPFYRYKTYHDWLQ-----------QPDSLYIPSWRPLLlrlrPAPVFGLLFFLVSYLFPLAYVQTDEFY 222
Cdd:PLN02332  167 YCLCCGSHLAGPVFEFRDYLDWTEgkglwdpnakgKCPSPYGATLRALL----QAAICMGLYLYLTPQFPLSRFTEPDYQ 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 223 ERPFLYRLFYMAPTFFVFRMRFYVAWIFAECGCIAAafgaypaaaksrpGGGPTvdytsaGRSPEGERLAidyDYETVKN 302
Cdd:PLN02332  243 EWGFWHRFGYQYMSGFTARWKYYFIWSISEAAIIIS-------------GLGFS------GWDGEGKPKA---KWDRAKN 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 303 IDCYGTDFCVKVKDGMRYWNMTVQWWLAQYIY-------KNAPLRSFIFrstwTMLISAYWHGIHPGYYLSFLTIPLCLA 375
Cdd:PLN02332  301 VDILGVELAKSAVQIPLVWNIQVSTWLRHYVYerlvpkgKKPGFFQLLA----TQTVSAVWHGLYPGYILFFVQSALMIA 376
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1835671658 376 AEGAMEVGLRHHLSSSGQLV--FDWVQWFLKMRAYDYMCMGFVLLTFSDTVRYWGSIYYCIHMLALGLMLVG 445
Cdd:PLN02332  377 GSRVIYRWQQAIPPSMALARnlLVFINFLYTVLVLNYSCVGFMLLSLDETLAAYGSVYYIGTIIPVVLILLG 448
COG5202 COG5202
Predicted membrane protein [Function unknown];
3-456 7.72e-35

Predicted membrane protein [Function unknown];


Pssm-ID: 227529  Cd Length: 512  Bit Score: 136.25  E-value: 7.72e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658   3 PDELTYLAILIFSIPIGFVFKS--KGPSVKQLGGAALGVLLILLTCHIHS--LHSLITILGTWLILKLTPRSCHFLVLSW 78
Cdd:COG5202    20 YLELRFLACLLLTLPFVSILKRnpTRIRTHNLFSISLILFYLFGVRHLVSgaYILASISLFTYLLRYFYRSAYMPTVLFI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658  79 TFIYLLF-FRTVTYFRLPPPTPF-ANAVQLLLTLKMVSLAnevQEYYSAK--RQDMSSFRKPAAIgviPRIPNLVETLCY 154
Cdd:COG5202   100 VILGHYKiFHAAQLFEERISTSFdITGSQMVLTMKLTSFA---WSYYDGKeySSDLTEHQKSRAR---RGTPTVLDFLSY 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 155 SYCYMGLMTGPFYRYKTYHDWLQQ------PDSLY-----IPSWRPLLLRLRPAPVFGLLFFLVSYLFPLAYVQTDEFYE 223
Cdd:COG5202   174 IFFIPGLLLGPAFDYADFDSWLTCemfrslMENPYerpkrPPNGKLALATFLKGLGWLILFQVGRISIPRKHLLEEDFPV 253
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 224 RPFLYRLFYMAPTFFVFRMRFYVAWIFAECGCIAAafgaypaaaksrpgggptvdytsaGRSPEGERLAIDYDYETVKNI 303
Cdd:COG5202   254 RLLPMRWAYLYLFTFGNRIKYYFAWHFSHGSCILF------------------------GLGYNGPDSTQKIRWDRVRNI 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 304 DCYGTDFCVKVKDGMRYWNMTVQWWLAQYIY-KNAPL-RSFIFRST-WTMLISAYWHGIHPGYYLSFLTiplcLAAEGAM 380
Cdd:COG5202   310 DFMKVELATNVKDLLEAWNMNTNKWLKNSVYlRVVKKgKKPGFWSTlGTFAISALWHGINPGYYLTFLS----LAASQTI 385
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 381 EVGLRHHLSS-------SGQLVFDWVQWFLKMRA----YDYMCMGFVLLTFSDTVRYWGSIYYCIHMlalgLMLVGHALA 449
Cdd:COG5202   386 VKENRRLLRPfflredgVTPLPSKSLYDVLGRIAmlllTTYFSASFFLLSLKDSMYVWRSVYFAVHI----FLAFSLAVF 461

                  ....*..
gi 1835671658 450 SGVTRSP 456
Cdd:COG5202   462 IAPIRKK 468
MBOAT pfam03062
MBOAT, membrane-bound O-acyltransferase family; The MBOAT (membrane bound O-acyl transferase) ...
122-380 2.29e-17

MBOAT, membrane-bound O-acyltransferase family; The MBOAT (membrane bound O-acyl transferase) family of membrane proteins contains a variety of acyltransferase enzymes. A conserved histidine has been suggested to be the active site residue.


Pssm-ID: 427117  Cd Length: 334  Bit Score: 82.87  E-value: 2.29e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 122 YYSAKRQDMSSFRKPAAIGVIPRIPNLVETLCYSYCYMGLMTGPFYRYKTYHDWLQQP----DSLYIPSWRPLLLRLRPA 197
Cdd:pfam03062  55 LLFSYRPVSLSFRKLASAAALSQDPSLLEYLGYVFFYPGLLVGPIFSYSDYMSFPRDPlfrwLYYVKRNLAPALGALFLG 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 198 PVFGLLFFLVSYLFPLAYVQTDEFYERPFLYRLFYMAPTFFVFRMRFYVAWIFAECgciaaafgayPAAAKSRPGGGPTV 277
Cdd:pfam03062 135 LTYLILIQYLLSHLPDKDFSKFKFLSYAFLLRFSVIMRILLGLLWLFLLIFDFLGW----------LFAEGEDILFGLGF 204
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1835671658 278 DYTSagrspegerlaidydyeTVKNIDCYGT-DFCVKVKDGMRYWNMTVQWWLAQYIYK---NAPLRSFIFRSTWTMLIS 353
Cdd:pfam03062 205 NGWD-----------------RVAPENIYRCwENAVSFSEFWRAWNIPVHKWLKRYVYKplgKKGKLNKFLATLATFLFS 267
                         250       260
                  ....*....|....*....|....*..
gi 1835671658 354 AYWHGIHPGYYLSFLTIPLCLAAEGAM 380
Cdd:pfam03062 268 AVWHGYYLGYLLWFVLRVLLLLAEKLI 294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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