NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1812289002|ref|XP_032441533|]
View 

heparan sulfate glucosamine 3-O-sulfotransferase 5 [Xiphophorus hellerii]

Protein Classification

sulfotransferase family protein( domain architecture ID 229543)

sulfotransferase family protein may utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to its substrate(s)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Sulfotransfer_1 super family cl21551
Sulfotransferase domain;
89-329 3.11e-32

Sulfotransferase domain;


The actual alignment was detected with superfamily member pfam00685:

Pssm-ID: 473908 [Multi-domain]  Cd Length: 253  Bit Score: 120.91  E-value: 3.11e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002  89 LPRAIIIGVRKGGTRALLEMLNLHPAV--VKASQEIHFFDNdKNYARGIDWYRGKmplslphqitiekspAYFITEEVPE 166
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGD---------------TYFDVAEGPV 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002 167 RIFKMNS--------------------SIKLLIIVREPTTRAVSDYTQVLEGKERKNKTYHKFEnlaidantcEVNTKYK 226
Cdd:pfam00685  65 RLNALPSpriikthlplhllpkslwdpNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEF---------VEDFLNG 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002 227 AVRTSIYTKHLERWLKYFPVEQFHIVDGDRLITDPLPELQLVERFLNLPSRISQ-----YNLYFNATRGFYCLRFNII-- 299
Cdd:pfam00685 136 KVNCGSYFDHVKGWWKLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGNPCLNYSKLpk 215

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1812289002 300 -----FNKCLAGSKgriHPEVDPSVVTKLQKFFHP 329
Cdd:pfam00685 216 evspfFRKGLVGDW---KNYFTPEQAEKFDEIYQE 247
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
89-329 3.11e-32

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 120.91  E-value: 3.11e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002  89 LPRAIIIGVRKGGTRALLEMLNLHPAV--VKASQEIHFFDNdKNYARGIDWYRGKmplslphqitiekspAYFITEEVPE 166
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGD---------------TYFDVAEGPV 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002 167 RIFKMNS--------------------SIKLLIIVREPTTRAVSDYTQVLEGKERKNKTYHKFEnlaidantcEVNTKYK 226
Cdd:pfam00685  65 RLNALPSpriikthlplhllpkslwdpNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEF---------VEDFLNG 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002 227 AVRTSIYTKHLERWLKYFPVEQFHIVDGDRLITDPLPELQLVERFLNLPSRISQ-----YNLYFNATRGFYCLRFNII-- 299
Cdd:pfam00685 136 KVNCGSYFDHVKGWWKLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGNPCLNYSKLpk 215

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1812289002 300 -----FNKCLAGSKgriHPEVDPSVVTKLQKFFHP 329
Cdd:pfam00685 216 evspfFRKGLVGDW---KNYFTPEQAEKFDEIYQE 247
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
89-329 3.11e-32

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 120.91  E-value: 3.11e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002  89 LPRAIIIGVRKGGTRALLEMLNLHPAV--VKASQEIHFFDNdKNYARGIDWYRGKmplslphqitiekspAYFITEEVPE 166
Cdd:pfam00685   1 DDDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGD---------------TYFDVAEGPV 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002 167 RIFKMNS--------------------SIKLLIIVREPTTRAVSDYTQVLEGKERKNKTYHKFEnlaidantcEVNTKYK 226
Cdd:pfam00685  65 RLNALPSpriikthlplhllpkslwdpNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEF---------VEDFLNG 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002 227 AVRTSIYTKHLERWLKYFPVEQFHIVDGDRLITDPLPELQLVERFLNLPSRISQ-----YNLYFNATRGFYCLRFNII-- 299
Cdd:pfam00685 136 KVNCGSYFDHVKGWWKLRPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEEldkivKHLSFENMKGNPCLNYSKLpk 215

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1812289002 300 -----FNKCLAGSKgriHPEVDPSVVTKLQKFFHP 329
Cdd:pfam00685 216 evspfFRKGLVGDW---KNYFTPEQAEKFDEIYQE 247
Sulfotransfer_3 pfam13469
Sulfotransferase family;
93-275 1.38e-11

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 62.31  E-value: 1.38e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002  93 IIIGVRKGGTRALLEMLNLHPAVvkASQEIHFFDNDKNYARGIDW---YRGKMPLSLPHQITIEKSPAYFiteEVPERIF 169
Cdd:pfam13469   2 FIVGLPRSGTTLLHRLLAAHPDV--RPPEETWFVIPRILALLQAWgksLEALARVPSYARWLCDKSPSHL---FHLDLLL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812289002 170 KMNSSIKLLIIVREPTTRAVSDYTQVLEGKerkNKTYHKFENLAIDANTCEVNTKYKAVRtsiytkhlERWLKYFPvEQF 249
Cdd:pfam13469  77 KAFPDAKFIHLHRDPVDTVISSYCSLFGFT---LSSYSTAFLRDIGLALARWSRAYERLM--------AARARVPP-GRF 144

                         170       180
                  ....*....|....*....|....*.
gi 1812289002 250 HIVDGDRLITDPLPELQLVERFLNLP 275
Cdd:pfam13469 145 LDVRYEDLVADPEGTLRRILEFLGLP 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH