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Conserved domains on  [gi|1812348123|ref|XP_032423222|]
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phosphatidylinositol N-acetylglucosaminyltransferase subunit A isoform X2 [Xiphophorus hellerii]

Protein Classification

phosphatidylinositol N-acetylglucosaminyltransferase subunit A/GPI3( domain architecture ID 10133424)

phosphatidylinositol N-acetylglucosaminyltransferase subunit A/GPI3 is the catalytic subunit of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis

CAZY:  GT4
EC:  2.4.1.198
Gene Ontology:  GO:0017176|GO:0006486|GO:0006506
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT4_PIG-A-like cd03796
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ...
 31-398 0e+00

phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.


:

Pssm-ID: 340827 [Multi-domain]  Cd Length: 398  Bit Score: 627.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  31 NICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKV-----------------------------MYNQSTATTCFHSLPLL 81
Cdd:cd03796     1 RICMVSDFFYPNLGGVETHIYQLSQCLIKRGHKVivithaygnrvgvryltnglkvyylpfkvFYNQSTLPTLFSTFPLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  82 RCVFVRERITVVHAHSSFSAMAHDALFHAKTLGLNTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIVCVSYTSKENTV 161
Cdd:cd03796    81 RNILIRERIQIVHGHQAFSSLAHEALFHARTLGLKTVFTDHSLFGFADASSILTNKLLRFSLADIDHVICVSHTSKENTV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 162 LRAALNPEIVSVIPNAVDPTDFTPDPSQRPPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLE 241
Cdd:cd03796   161 LRASLDPRIVSVIPNAVDSSDFTPDPSKPDPNKITIVVISRLVYRKGIDLLVGIIPRICKKHPNVRFIIGGDGPKRIELE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 242 EVREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPEDLITLCEPTV 321
Cdd:cd03796   241 EMREKYQLQDRVELLGAVPHEEVRDVLVQGHIFLNTSLTEAFCIAIVEAASCGLLVVSTRVGGIPEVLPPDMILLAEPDP 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1812348123 322 RSLCAGLEKVIAKQRSGSvPFPTSIHSRVKNLYTWKNVAERTERVYDRVAgEEVLPLDRRLRRLRSHCGPVAGSLFA 398
Cdd:cd03796   321 EDIVRKLEEAISILRTGK-HDPWSFHNRVKKMYSWEDVARRTEKVYDRIL-STPNRPFLERLKRYYNCGPIAGKIFC 395
 
Name Accession Description Interval E-value
GT4_PIG-A-like cd03796
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ...
 31-398 0e+00

phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.


Pssm-ID: 340827 [Multi-domain]  Cd Length: 398  Bit Score: 627.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  31 NICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKV-----------------------------MYNQSTATTCFHSLPLL 81
Cdd:cd03796     1 RICMVSDFFYPNLGGVETHIYQLSQCLIKRGHKVivithaygnrvgvryltnglkvyylpfkvFYNQSTLPTLFSTFPLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  82 RCVFVRERITVVHAHSSFSAMAHDALFHAKTLGLNTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIVCVSYTSKENTV 161
Cdd:cd03796    81 RNILIRERIQIVHGHQAFSSLAHEALFHARTLGLKTVFTDHSLFGFADASSILTNKLLRFSLADIDHVICVSHTSKENTV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 162 LRAALNPEIVSVIPNAVDPTDFTPDPSQRPPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLE 241
Cdd:cd03796   161 LRASLDPRIVSVIPNAVDSSDFTPDPSKPDPNKITIVVISRLVYRKGIDLLVGIIPRICKKHPNVRFIIGGDGPKRIELE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 242 EVREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPEDLITLCEPTV 321
Cdd:cd03796   241 EMREKYQLQDRVELLGAVPHEEVRDVLVQGHIFLNTSLTEAFCIAIVEAASCGLLVVSTRVGGIPEVLPPDMILLAEPDP 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1812348123 322 RSLCAGLEKVIAKQRSGSvPFPTSIHSRVKNLYTWKNVAERTERVYDRVAgEEVLPLDRRLRRLRSHCGPVAGSLFA 398
Cdd:cd03796   321 EDIVRKLEEAISILRTGK-HDPWSFHNRVKKMYSWEDVARRTEKVYDRIL-STPNRPFLERLKRYYNCGPIAGKIFC 395
PIGA pfam08288
PIGA (GPI anchor biosynthesis); This domain is found on phosphatidylinositol ...
 63-129 5.00e-33

PIGA (GPI anchor biosynthesis); This domain is found on phosphatidylinositol n-acetylglucosaminyltransferase proteins. These proteins are involved in GPI anchor biosynthesis and are associated with disease the paroxysmal nocturnal haemoglobinuria.


Pssm-ID: 400541  Cd Length: 90  Bit Score: 119.67  E-value: 5.00e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1812348123  63 KVMYNQSTATTCFHSLPLLRCVFVRERITVVHAHSSFSAMAHDALFHAKTLGLNTVFTDHSLFGFAD 129
Cdd:pfam08288  24 LVIYRQSTFPTVFGTFPLFRNILLRERIDIVHGHGSFSTLAHEAILHARTMGLKTVFTDHSLFGFAD 90
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 264-370 3.10e-13

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 66.17  E-value: 3.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 264 VRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPEDLI-TLCEP-TVRSLCAGLEKVIAkQRSGSVP 341
Cdd:COG0438    14 LEALLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETgLLVPPgDPEALAEAILRLLE-DPELRRR 92

                          90       100
                  ....*....|....*....|....*....
gi 1812348123 342 FPTSIHSRVKNLYTWKNVAERTERVYDRV 370
Cdd:COG0438    93 LGEAARERAEERFSWEAIAERLLALYEEL 121
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
171-366 9.68e-08

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 53.64  E-value: 9.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 171 VSVIPNAVDP----TDFTPDPSQR---PPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGE------GPKR 237
Cdd:PRK15484  163 ISIVPNGFCLetyqSNPQPNLRQQlniSPDETVLLYAGRISPDKGILLLMQAFEKLATAHSNLKLVVVGDptasskGEKA 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 238 LVLEEVRE-KYQLHDRVRLLGALE----HKDVRgvlVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPED 312
Cdd:PRK15484  243 AYQKKVLEaAKRIGDRCIMLGGQPpekmHNYYP---LADLVVVPSQVEEAFCMVAVEAMAAGKPVLASTKGGITEFVLEG 319

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1812348123 313 lIT---LCEP-TVRSLCAGLEKVIAKqrsgsvPFPTSIHSRVKNL----YTWKNVAERTERV 366
Cdd:PRK15484  320 -ITgyhLAEPmTSDSIISDINRTLAD------PELTQIAEQAKDFvfskYSWEGVTQRFEEQ 374
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 168-303 2.58e-04

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 43.38  E-value: 2.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 168 PEIVSVIPNAVDPTDFTPDPSQRPPDRITIV-VISRLVYRKGIDLLGGIIPELCLKHPDLH-FLIGGEGPKRLVLEEVR- 244
Cdd:NF038011  279 PERTRVIPNGIDLPRLAPLRAQRPAGIPPVVgLIGRVVPIKDIKTFIRAMRTVVRAMPEAEgWIVGPEEEDPAYAAECRs 358

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1812348123 245 --EKYQLHDRVRLLGaleHKDVRGVLVQ-GHIFLnTSLTEAFCMAIVEGASCGLQVVSTRVG 303
Cdd:NF038011  359 lvASLGLQDKVKFLG---FQKIDDLLPQvGLMVL-SSISEALPLVVLEAFAAGVPVVTTDVG 416
 
Name Accession Description Interval E-value
GT4_PIG-A-like cd03796
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ...
 31-398 0e+00

phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.


Pssm-ID: 340827 [Multi-domain]  Cd Length: 398  Bit Score: 627.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  31 NICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKV-----------------------------MYNQSTATTCFHSLPLL 81
Cdd:cd03796     1 RICMVSDFFYPNLGGVETHIYQLSQCLIKRGHKVivithaygnrvgvryltnglkvyylpfkvFYNQSTLPTLFSTFPLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  82 RCVFVRERITVVHAHSSFSAMAHDALFHAKTLGLNTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIVCVSYTSKENTV 161
Cdd:cd03796    81 RNILIRERIQIVHGHQAFSSLAHEALFHARTLGLKTVFTDHSLFGFADASSILTNKLLRFSLADIDHVICVSHTSKENTV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 162 LRAALNPEIVSVIPNAVDPTDFTPDPSQRPPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLE 241
Cdd:cd03796   161 LRASLDPRIVSVIPNAVDSSDFTPDPSKPDPNKITIVVISRLVYRKGIDLLVGIIPRICKKHPNVRFIIGGDGPKRIELE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 242 EVREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPEDLITLCEPTV 321
Cdd:cd03796   241 EMREKYQLQDRVELLGAVPHEEVRDVLVQGHIFLNTSLTEAFCIAIVEAASCGLLVVSTRVGGIPEVLPPDMILLAEPDP 320

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1812348123 322 RSLCAGLEKVIAKQRSGSvPFPTSIHSRVKNLYTWKNVAERTERVYDRVAgEEVLPLDRRLRRLRSHCGPVAGSLFA 398
Cdd:cd03796   321 EDIVRKLEEAISILRTGK-HDPWSFHNRVKKMYSWEDVARRTEKVYDRIL-STPNRPFLERLKRYYNCGPIAGKIFC 395
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 31-367 2.27e-55

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 187.75  E-value: 2.27e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  31 NICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKV-----------------------MYNQSTATTCFHSLPLLRCVFVR 87
Cdd:cd03801     1 KILLLSPELPPPVGGAERHVRELARALAARGHDVtvltpadpgeppeeledgvivplLPSLAALLRARRLLRELRPLLRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  88 ERITVVHAHSSFSAMAhdALFHAKTLGLNTVFTDHSLFGF------ADVSSVLTNKLLTVSLCDtnHIVCVSYTSKENTV 161
Cdd:cd03801    81 RKFDVVHAHGLLAALL--AALLALLLGAPLVVTLHGAEPGrlllllAAERRLLARAEALLRRAD--AVIAVSEALRDELR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 162 LRAALNPEIVSVIPNAVDPTDFTPDPSQR---PPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLI-GGEGPKR 237
Cdd:cd03801   157 ALGGIPPEKIVVIPNGVDLERFSPPLRRKlgiPPDRPVLLFVGRLSPRKGVDLLLEALAKLLRRGPDVRLVIvGGDGPLR 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 238 LVLEEvrEKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLP-EDLITL 316
Cdd:cd03801   237 AELEE--LELGLGDRVRFLGFVPDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEVVEdGEGGLV 314

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1812348123 317 CEPT-VRSLCAGLEKVI-----AKQRSgsvpfpTSIHSRVKNLYTWKNVAERTERVY 367
Cdd:cd03801   315 VPPDdVEALADALLRLLadpelRARLG------RAARERVAERFSWERVAERLLDLY 365
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 32-319 1.61e-36

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 137.10  E-value: 1.61e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  32 ICMVSDFFYpnMGGVESHIYQLSQCLIEKGHKVM-----------YNQSTATTCFHSLPLLRC---------VFVRERIT 91
Cdd:cd03819     1 ILMLTPALE--IGGAETYILDLARALAERGHRVLvvtaggpllprLRQIGIGLPGLKVPLLRAllgnvrlarLIRRERID 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  92 VVHAHSSFSAMAhdALFHAKTLGLNTVFTDHSLfgfaDVSSVLTNKLLTVSLCDTNHIVCVSYTSKENTVLRAALNPEIV 171
Cdd:cd03819    79 LIHAHSRAPAWL--GWLASRLTGVPLVTTVHGS----YLATYHPKDFALAVRARGDRVIAVSELVRDHLIEALGVDPERI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 172 SVIPNAVDPTDFTPDPSQR-------PPDRITIVVISRLVYRKGIDLLGGIIPELcLKHPDLHFLIGGEGPKRLVLEEVR 244
Cdd:cd03819   153 RVIPNGVDTDRFPPEAEAEeraqlglPEGKPVVGYVGRLSPEKGWLLLVDAAAEL-KDEPDFRLLVAGDGPERDEIRRLV 231

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812348123 245 EKYQLHDRVRLLGAleHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPEDLITLCEP 319
Cdd:cd03819   232 ERLGLRDRVTFTGF--REDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVHGRTGLLVP 304
PIGA pfam08288
PIGA (GPI anchor biosynthesis); This domain is found on phosphatidylinositol ...
 63-129 5.00e-33

PIGA (GPI anchor biosynthesis); This domain is found on phosphatidylinositol n-acetylglucosaminyltransferase proteins. These proteins are involved in GPI anchor biosynthesis and are associated with disease the paroxysmal nocturnal haemoglobinuria.


Pssm-ID: 400541  Cd Length: 90  Bit Score: 119.67  E-value: 5.00e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1812348123  63 KVMYNQSTATTCFHSLPLLRCVFVRERITVVHAHSSFSAMAHDALFHAKTLGLNTVFTDHSLFGFAD 129
Cdd:pfam08288  24 LVIYRQSTFPTVFGTFPLFRNILLRERIDIVHGHGSFSTLAHEAILHARTMGLKTVFTDHSLFGFAD 90
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 31-370 8.50e-31

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 122.00  E-value: 8.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  31 NICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKV------------------MYNQSTATTCFHSLPLLRCV-------F 85
Cdd:cd03817     1 KIAIFTDTYLPQVNGVATSVRNLARALEKRGHEVyvitpsdpgaedeeevvrYRSFSIPIRKYHRQHIPFPFkkavidrI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  86 VRERITVVHAHSSFSAMAHdALFHAKTLGLNTVFTDHSL---------FGFADVSSVLtnKLLTVSLCD-TNHIVCVSYT 155
Cdd:cd03817    81 KELGPDIIHTHTPFSLGKL-GLRIARKLKIPIVHTYHTMyedylhyipKGKLLVKAVV--RKLVRRFYNhTDAVIAPSEK 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 156 SKEntVLRAALNPEIVSVIPNAVDPTDF--TPDPSQR-----PPDRITIVVISRLVYRKGIDLLGGIIPELcLKHPDLHF 228
Cdd:cd03817   158 IKD--TLREYGVKGPIEVIPNGIDLDKFekPLNTEERrklglPPDEPILLYVGRLAKEKNIDFLLRAFAEL-KKEPNIKL 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 229 LIGGEGPKRLVLEEVREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEV 308
Cdd:cd03817   235 VIVGDGPEREELKELARELGLADKVIFTGFVPREELPEYYKAADLFVFASTTETQGLVYLEAMAAGLPVVAAKDPAASEL 314

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812348123 309 LpEDLIT--LCEPTVRSLCAGLEKVIAKQRSgsvpfpTSIHSRVKNLYTWK-NVAERTERVYDRV 370
Cdd:cd03817   315 V-EDGENgfLFEPNDETLAEKLLHLRENLEL------LRKLSKNAEISAREfAFAKSVEKLYEEV 372
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 78-370 9.93e-31

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 121.72  E-value: 9.93e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  78 LPLLRcVFVRERITVVHAHSSFSA-MAhdALFHAKTLGLNTVFTDHS--LFGFADVSSVLTNKLLTVSLCDtnhivCVSY 154
Cdd:cd03798    85 AKLLK-RRRRGPPDLIHAHFAYPAgFA--AALLARLYGVPYVVTEHGsdINVFPPRSLLRKLLRWALRRAA-----RVIA 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 155 TSKE--NTVLRAALNPEIVSVIPNAVDPTDFTPDPSQ--RPPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLI 230
Cdd:cd03798   157 VSKAlaEELVALGVPRDRVDVIPNGVDPARFQPEDRGlgLPLDAFVILFVGRLIPRKGIDLLLEAFARLAKARPDVVLLI 236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 231 GGEGPKRLVLEEVREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLp 310
Cdd:cd03798   237 VGDGPLREALRALAEDLGLGDRVTFTGRLPHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIPEVV- 315

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812348123 311 EDLIT--LCEPT-VRSLCAGLEKVIAKQRSGSVpfPTSIHSRVKNLYTWKNVAERTERVYDRV 370
Cdd:cd03798   316 GDPETglLVPPGdADALAAALRRALAEPYLREL--GEAARARVAERFSWVKAADRIAAAYRDV 376
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 38-309 3.69e-30

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 119.77  E-value: 3.69e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  38 FFYPNM--GGVESHIYQLSQCLIEKGHKV---------------MYNQSTATTCFHSLPL-----------LRCVFVRER 89
Cdd:cd03811     4 FVIPSLsgGGAERVLLNLANALDKRGYDVtlvllrdegdldkqlNGDVKLIRLLIRVLKLiklgllkailkLKRILKRAK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  90 ITVVHAHSSFSAmahDALFHAKTLGLNTVFTDHSlfgFADVSSVLTNKLLTVSLC--DTNHIVCVSYTSKENTVLRAALN 167
Cdd:cd03811    84 PDVVISFLGFAT---YIVAKLAAARSKVIAWIHS---SLSKLYYLKKKLLLKLKLykKADKIVCVSKGIKEDLIRLGPSP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 168 PEIVSVIPNAVDPTDFTPDPSQR----PPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEEV 243
Cdd:cd03811   158 PEKIEVIYNPIDIDRIRALAKEPilnePEDGPVILAVGRLDPQKGHDLLIEAFAKLRKKYPDVKLVILGDGPLREELEKL 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1812348123 244 REKYQLHDRVRLLGalEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVL 309
Cdd:cd03811   238 AKELGLAERVIFLG--FQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPREIL 301
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 77-333 1.15e-29

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 118.57  E-value: 1.15e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  77 SLPLLRCVFVRERITVVHAHssfsaMAHDALF---HAK-TLGLNTVFTDHSLFGFADVSSVL--TNKLLTVSLCDTnhiV 150
Cdd:cd03807    67 VLLRLAKLIRKRNPDVVHTW-----MYHADLIgglAAKlAGGVKVIWSVRSSNIPQRLTRLVrkLCLLLSKFSPAT---V 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 151 CVSYTSKEnTVLRAALNPEIVSVIPNAVDPTDFTPDPSQR---------PPDRITIVVISRLVYRKGIDLLGGIIPELCL 221
Cdd:cd03807   139 ANSSAVAE-FHQEQGYAKNKIVVIYNGIDLFKLSPDDASRararrrlglAEDRRVIGIVGRLHPVKDHSDLLRAAALLVE 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 222 KHPDLHFLIGGEGPKRLVLEEVREKYQLHDRVRLLGalEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTR 301
Cdd:cd03807   218 THPDLRLLLVGRGPERPNLERLLLELGLEDRVHLLG--ERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATD 295

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1812348123 302 VGGIPEVLPEDLITLCEP-TVRSLCAGLEKVIA 333
Cdd:cd03807   296 VGGAAELVDDGTGFLVPAgDPQALADAIRALLE 328
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 42-308 4.02e-28

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 114.23  E-value: 4.02e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  42 NMGGVESHIYQLSQCLIEKGHKV----MYNQSTATTC------FHSLPLLRC----------------VFVRERITVVHA 95
Cdd:cd03808     8 VDGGFQSFRLPLIKALVKKGYEVhviaPDGDKLSDELkelgvkVIDIPILRRginplkdlkalfklykLLKKEKPDIVHC 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  96 HSSFSAMAhdALFHAKTLG-LNTVFTDHSLfGFADVSSVLTNKLLTV----SLCDTNHIVCVSYTSKENTV-LRAALNPE 169
Cdd:cd03808    88 HTPKPGIL--GRLAARLAGvPKVIYTVHGL-GFVFTEGKLLRLLYLLleklALLFTDKVIFVNEDDRDLAIkKGIIKKKK 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 170 IVSVIPNAVDPTDFTPDPSQRPPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEEVREKYQL 249
Cdd:cd03808   165 TVLIPGSGVDLDRFQYSPESLPSEKVVFLFVARLLKDKGIDELIEAAKILKKKGPNVRFLLVGDGELENPSEILIEKLGL 244

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1812348123 250 HDRVRLLGalEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEV 308
Cdd:cd03808   245 EGRIEFLG--FRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCREL 301
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 32-312 3.68e-26

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 105.95  E-value: 3.68e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  32 ICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKVMynqsTATTCFHSLPLLRCVFVRERITVVHAHSSFSAMAHdALFHAK 111
Cdd:cd01635     1 ILLVTGEYPPLRGGLELHVRALARALAALGHEVT----VLALLLLALRRILKKLLELKPDVVHAHSPHAAALA-ALLAAR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 112 TLGLNTVFTDHSL-FGFADVSSVLTNKLLTVSLCDTNHivcvsytskentvlraalnpeivsvipnavdptdftpdpsqr 190
Cdd:cd01635    76 LLGIPIVVTVHGPdSLESTRSELLALARLLVSLPLADK------------------------------------------ 113

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 191 ppdritiVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEEVREKYQLHDRVRLLGALEHKDVRGVLVQ 270
Cdd:cd01635   114 -------VSVGRLVPEKGIDLLLEALALLKARLPDLVLVLVGGGGEREEEEALAAALGLLERVVIIGGLVDDEVLELLLA 186

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1812348123 271 G-HIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPED 312
Cdd:cd01635   187 AaDVFVLPSRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVDG 229
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 193-337 1.33e-23

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 96.57  E-value: 1.33e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 193 DRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEEVREKYQLHDRVRLLGALEHKDVRGVLVQGH 272
Cdd:pfam00534   1 KKKIILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPELLKIAD 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1812348123 273 IFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLpEDLIT--LCEPT-VRSLCAGLEKVIAKQRS 337
Cdd:pfam00534  81 VFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVV-KDGETgfLVKPNnAEALAEAIDKLLEDEEL 147
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
194-309 2.37e-23

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 94.89  E-value: 2.37e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 194 RITIVVISRLV-YRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEEVREkyqLHDRVRLLGALEhkDVRGVLVQGH 272
Cdd:pfam13692   1 RPVILFVGRLHpNVKGVDYLLEAVPLLRKRDNDVRLVIVGDGPEEELEELAAG---LEDRVIFTGFVE--DLAELLAAAD 75

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1812348123 273 IFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVL 309
Cdd:pfam13692  76 VFVLPSLYEGFGLKLLEAMAAGLPVVATDVGGIPELV 112
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 42-299 7.70e-22

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 96.15  E-value: 7.70e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  42 NMGGVESHIYQLSQCLIEKGHKVM--YNQSTATTCFHSLPL---------------------------LRCVFVRER--I 90
Cdd:cd03820    11 NAGGAERVAINLANHLAKKGYDVTiiSLDSAEKPPFYELDDnikiknlgdrkyshfklllkyfkkvrrLRKYLKNNKpdV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  91 TVVHAHSSFSAMAhdalfhAKTLGLNTVFTDHSLFGFA-DVSSVLTNKLLTVSLCDTnhIVCVSYTSKENTvlRAALNPE 169
Cdd:cd03820    91 VISFRTSLLTFLA------LIGLKSKLIVWEHNNYEAYnKGLRRLLLRRLLYKRADK--IVVLTEADKLKK--YKQPNSN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 170 IVsVIPNAVDPTDFTPdpsQRPPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEEVREKYQL 249
Cdd:cd03820   161 VV-VIPNPLSFPSEEP---STNLKSKRILAVGRLTYQKGFDLLIEAWALIAKKHPDWKLRIYGDGPEREELEKLIDKLGL 236

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1812348123 250 HDRVRLLGALehKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVS 299
Cdd:cd03820   237 EDRVKLLGPT--KNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIIS 284
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 149-307 8.26e-22

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 96.37  E-value: 8.26e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 149 IVCVSYTSKENtVLRAALNPEIVSVIPNAVDPTDFTPDPsqRPPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHF 228
Cdd:cd05844   147 FVAVSGFIRDR-LLARGLPAERIHVHYIGIDPAKFAPRD--PAERAPTILFVGRLVEKKGCDVLIEAFRRLAARHPTARL 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 229 LIGGEGPKRLVLEEVREKYqlhDRVRLLGALEHKDVRGVLVQGHIFLNTSLT------EAFCMAIVEGASCGLQVVSTRV 302
Cdd:cd05844   224 VIAGDGPLRPALQALAAAL---GRVRFLGALPHAEVQDWMRRAEIFCLPSVTaasgdsEGLGIVLLEAAACGVPVVSSRH 300


                  ....*
gi 1812348123 303 GGIPE 307
Cdd:cd05844   301 GGIPE 305
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 31-367 9.16e-22

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 95.86  E-value: 9.16e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  31 NICMVSDFFYPN-MGGVESHIYQLSQCLIEKGHKV-----------------------------MYNQSTATTCFHS--- 77
Cdd:cd03823     1 KILLVNSLYPPQrVGGAEISVHDLAEALVAEGHEVavltagvgppgqatvarsvvryrrapdetLPLALKRRGYELFety 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  78 ----LPLLRCVFVRERITVVHAHSsFSAMAHDALFHAKTLGLNTVFTDHSLFGFADVSSVLTNKLLTVslcdtnhiVCVS 153
Cdd:cd03823    81 npglRRLLARLLEDFRPDVVHTHN-LSGLGASLLDAARDLGIPVVHTLHDYWLLCPRQFLFKKGGDAV--------LAPS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 154 -YTskENTVLRAALNPEIVSVIPNAVDPTDFTPDPSQRPPDRITIVVISRLVYRKGIDLLGGIIPElcLKHPDLHFLIGG 232
Cdd:cd03823   152 rFT--ANLHEANGLFSARISVIPNAVEPDLAPPPRRRPGTERLRFGYIGRLTEEKGIDLLVEAFKR--LPREDIELVIAG 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 233 EGPkrlvlEEVREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSL-TEAFCMAIVEGASCGLQVVSTRVGGIPEVLPE 311
Cdd:cd03823   228 HGP-----LSDERQIEGGRRIAFLGRVPTDDIKDFYEKIDVLVVPSIwPEPFGLVVREAIAAGLPVIASDLGGIAELIQP 302

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1812348123 312 DLI-TLCEPT-VRSLCAGLEKVIAKQRsgsvpFPTSIHSRVKNLYTWKNVAERTERVY 367
Cdd:cd03823   303 GVNgLLFAPGdAEDLAAAMRRLLTDPA-----LLERLRAGAEPPRSTESQAEEYLKLY 355
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 92-365 7.14e-21

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 93.84  E-value: 7.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  92 VVHAHSSFSAMAhdALFHAKTLGLNTVFTDHSLfGfadvssvlTNKLLTVSLCDTNHIVC---------------VSYTS 156
Cdd:cd03800   104 LIHSHYWDSGLV--GALLARRLGVPLVHTFHSL-G--------RVKYRHLGAQDTYHPSLritaeeqileaadrvIASTP 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 157 KENTVLRA--ALNPEIVSVIPNAVDPTDFTPDPSQR--------PPDRITIVVISRLVYRKGIDLL---GGIIPELCLKH 223
Cdd:cd03800   173 QEADELISlyGADPSRINVVPPGVDLERFFPVDRAEarrarlllPPDKPVVLALGRLDPRKGIDTLvraFAQLPELRELA 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 224 pDLHFLIGGEGPK----RLVLEEVREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVS 299
Cdd:cd03800   253 -NLVLVGGPSDDPlsmdREELAELAEELGLIDRVRFPGRVSRDDLPELYRAADVFVVPSLYEPFGLTAIEAMACGTPVVA 331

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812348123 300 TRVGGIPEVLpEDLIT--LCEPT-VRSLCAGLEKVIAK----QRSGSvpfptSIHSRVKNLYTWKNVAERTER 365
Cdd:cd03800   332 TAVGGLQDIV-RDGRTglLVDPHdPEALAAALRRLLDDpalwQRLSR-----AGLERARAHYTWESVADQLLT 398
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 45-364 7.47e-21

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 93.59  E-value: 7.47e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  45 GVESHIYQLSQCLIEKGHKVMYNQSTATTCFHSLPLLRC------------VFVRERIT---VVHAHSSFSAMAHDALFH 109
Cdd:cd03821    31 GHEVTIVSTGDGYESLVVEENGRYIPPQDGFASIPLLRQgagrtdfspglpNWLRRNLReydVVHIHGVWTYTSLAACKL 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 110 AKTLGLNTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHI---VCVSYTS-KENTVLRAALNPEIVSVIPNAVDPTDFTP 185
Cdd:cd03821   111 ARRRGIPYVVSPHGMLDPWALQQKHWKKRIALHLIERRNLnnaALVHFTSeQEADELRRFGLEPPIAVIPNGVDIPEFDP 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 186 DPSQR-----PPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPK-RLVLEEVREKYQLHDRVRLLGAL 259
Cdd:cd03821   191 GLRDRrkhngLEDRRIILFLGRIHPKKGLDLLIRAARKLAEQGRDWHLVIAGPDDGaYPAFLQLQSSLGLGDRVTFTGPL 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 260 EHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPEDLITLCEPTVRSLCAGLEKVI---AKQR 336
Cdd:cd03821   271 YGEAKWALYASADLFVLPSYSENFGNVVAEALACGLPVVITDKCGLSELVEAGCGVVVDPNVSSLAEALAEALrdpADRK 350

                         330       340       350
                  ....*....|....*....|....*....|
gi 1812348123 337 SgsvpFPTSIHS--RVKNLYTWKNVAERTE 364
Cdd:cd03821   351 R----LGEMARRarQVEENFSWEAVAGQLG 376
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 147-364 1.73e-18

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 86.65  E-value: 1.73e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 147 NHIVCVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPDPSQR------PPDRiTIVVISRLVYRKGIDLLGGIIPELC 220
Cdd:cd03809   140 DAIITVSEATRDDIIKFYGVPPEKIVVIPLGVDPSFFPPESAAVliakylLPEP-YFLYVGTLEPRKNHERLLKAFALLK 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 221 LKHPDLHFLI-GGEGPKRLVLEEVREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVS 299
Cdd:cd03809   219 KQGGDLKLVIvGGKGWEDEELLDLVKKLGLGGRVRFLGYVSDEDLPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVIA 298

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812348123 300 TRVGGIPEVLPEDlITLCEPT-VRSLCAGLEKVI-------AKQRSGsvpfptsiHSRVKNlYTWKNVAERTE 364
Cdd:cd03809   299 SNISVLPEVAGDA-ALYFDPLdPESIADAILRLLedpslreELIRKG--------LERAKK-FSWEKTAEKTL 361
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 167-312 3.87e-17

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 82.50  E-value: 3.87e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 167 NPEIVSVIPNAVDPTDFTPDPSQRPPD-RITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEEVRE 245
Cdd:cd03799   146 DEKKIIVHRSGIDCNKFRFKPRYLPLDgKIRILTVGRLTEKKGLEYAIEAVAKLAQKYPNIEYQIIGDGDLKEQLQQLIQ 225

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812348123 246 KYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSLT------EAFCMAIVEGASCGLQVVSTRVGGIPEvLPED 312
Cdd:cd03799   226 ELNIGDCVKLLGWKPQEEIIEILDEADIFIAPSVTaadgdqDGPPNTLKEAMAMGLPVISTEHGGIPE-LVED 297
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 32-311 7.48e-17

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 81.57  E-value: 7.48e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  32 ICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKVM-------YNQSTATTCFHSLPLLRC-------------VFVRERI- 90
Cdd:cd03814     2 IALVTDTYHPQVNGVVRTLERLVDHLRRRGHEVRvvapgpfDEAESAEGRVVSVPSFPLpfypeyrlalplpRRVRRLIk 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  91 ----TVVHAHSSFSaMAHDALFHAKTLGLNTVFTDHSLF-------GFADVSSVLTNKLLTVslcdTNHIVCVSYTSKEN 159
Cdd:cd03814    82 efqpDIIHIATPGP-LGLAALRAARRLGLPVVTSYHTDFpeylsyyTLGPLSWLAWAYLRWF----HNPFDTTLVPSPSI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 160 TVLRAALNPEIVSVIPNAVDPTDFtpDPSQR---------PPDRITIVVISRLVYRKGIDLLGGIIPELClKHPDLHFLI 230
Cdd:cd03814   157 ARELEGHGFERVRLWPRGVDTELF--HPSRRdaalrrrlgPPGRPLLLYVGRLAPEKNLEALLDADLPLA-ASPPVRLVV 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 231 GGEGPKRLVLEEVrekyqlHDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLP 310
Cdd:cd03814   234 VGDGPARAELEAR------GPDVIFTGFLTGEELARAYASADVFVFPSRTETFGLVVLEAMASGLPVVAADAGGPRDIVR 307


                  .
gi 1812348123 311 E 311
Cdd:cd03814   308 P 308
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 35-304 1.47e-15

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 77.70  E-value: 1.47e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  35 VSDFFYPNMGGVESHIYQLSQCLIEKGHKVMY-----NQSTATTCFHSLPLLRcvfVRERITVVHAHSSFSAmahdaLFH 109
Cdd:cd03795     5 VFKFYYPDIGGIEQVIYDLAEGLKKKGIEVDVlcfskEKETPEKEENGIRIHR---VKSFLNVASTPFSPSY-----IKR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 110 AKTLGLNT-VFTDHSLFGFADVSSVLTNK------------------------LLTVSLCDTNHIVCVSYTSKENT-VLR 163
Cdd:cd03795    77 FKKLAKEYdIIHYHFPNPLADLLLFFSGAkkpvvvhwhsdivkqkkllklykpLMTRFLRRADRIIATSPNYVETSpTLR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 164 AALNPeiVSVIPNAVDPTDFTPDPS-------QRPPDRItIVVISRLVYRKGIDLLggIIPELCLKHPdlhFLIGGEGPK 236
Cdd:cd03795   157 EFKNK--VRVIPLGIDKNVYNIPRVdfenikrEKKGKKI-FLFIGRLVYYKGLDYL--IEAAQYLNYP---IVIGGEGPL 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 237 RLVLEEvREKYQLHDRVRLLGALEHKDVRGVLVQGHIFLNTSL--TEAFCMAIVEGASCGLQVVSTRVGG 304
Cdd:cd03795   229 KPDLEA-QIELNLLDNVKFLGRVDDEEKVIYLHLCDVFVFPSVlrSEAFGIVLLEAMMCGKPVISTNIGT 297
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 84-311 9.06e-15

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 75.47  E-value: 9.06e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  84 VFVRERITVVHAHSsfsAMAHD-ALFHAKTL---GLNTVFTDHSlfgfADVSSVLTNK----LLTVSLCDTNHIVCVSYT 155
Cdd:cd04962    79 VAKEHKLDVLHAHY---AIPHAsCAYLAREIlgeKIPIVTTLHG----TDITLVGYDPslqpAVRFSINKSDRVTAVSSS 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 156 SKENTVLRAALNPEIvSVIPNAVDPTDFTPDPSQR-------PPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHF 228
Cdd:cd04962   152 LRQETYELFDVDKDI-EVIHNFIDEDVFKRKPAGAlkrrllaPPDEKVVIHVSNFRPVKRIDDVVRVFARVRRKIPAKLL 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 229 LIGgEGPKRLVLEEVREKYQLHDRVRLLGALEHkdVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEV 308
Cdd:cd04962   231 LVG-DGPERVPAEELARELGVEDRVLFLGKQDD--VEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIPEV 307


                  ...
gi 1812348123 309 LPE 311
Cdd:cd04962   308 VKH 310
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
44-180 4.21e-14

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 69.87  E-value: 4.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  44 GGVESHIYQLSQCLIEKGHKV----------MYNQSTATTCFHSLPL---------------LRCVFVRERITVVHAHSS 98
Cdd:pfam13439   1 GGVERYVLELARALARRGHEVtvvtpggpgpLAEEVVRVVRVPRVPLplpprllrslaflrrLRRLLRRERPDVVHAHSP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  99 FSAMAhDALFHAKTLGLNTVFTDHSLF-------GFADVSSVLTNKLLTVSLCDTNHIVCVSYTSKENTVLRAALNPEIV 171
Cdd:pfam13439  81 FPLGL-AALAARLRLGIPLVVTYHGLFpdykrlgARLSPLRRLLRRLERRLLRRADRVIAVSEAVADELRRLYGVPPEKI 159


                  ....*....
gi 1812348123 172 SVIPNAVDP 180
Cdd:pfam13439 160 RVIPNGVDL 168
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 264-370 3.10e-13

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 66.17  E-value: 3.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 264 VRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPEDLI-TLCEP-TVRSLCAGLEKVIAkQRSGSVP 341
Cdd:COG0438    14 LEALLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETgLLVPPgDPEALAEAILRLLE-DPELRRR 92

                          90       100
                  ....*....|....*....|....*....
gi 1812348123 342 FPTSIHSRVKNLYTWKNVAERTERVYDRV 370
Cdd:COG0438    93 LGEAARERAEERFSWEAIAERLLALYEEL 121
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 31-309 3.19e-13

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 70.83  E-value: 3.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  31 NICMVSDFFYPNMGGVESHIYQLSQCLIEKGHKV-----MYN------QSTATTCFHSLPLLR----------------- 82
Cdd:cd03794     1 KILLISQYYPPPKGAAAARVYELAKELVRRGHEVtvltpSPNyplgriFAGATETKDGIRVIRvklgpikknglirrlln 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  83 -----------CVFVRERITVVHAHSS--FSAMAhdALFHAKTLGLNTVFTDHSLFGFADVS-SVLTNKLL--------- 139
Cdd:cd03794    81 ylsfalaallkLLVREERPDVIIAYSPpiTLGLA--ALLLKKLRGAPFILDVRDLWPESLIAlGVLKKGSLlkllkkler 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 140 -TVSLCDtnHIVCVSYTSKENtVLRAALNPEIVSVIPNAVDPTDFTPDPSQR------PPDRITIVVISRLVYRKGIDLL 212
Cdd:cd03794   159 kLYRLAD--AIIVLSPGLKEY-LLRKGVPKEKIIVIPNWADLEEFKPPPKDElrkklgLDDKFVVVYAGNIGKAQGLETL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 213 GGIIPELcLKHPDLHFLIGGEGPKRLVLEEVREKYQLhDRVRLLGALEHKDVRGVLVQGHIFLNTSLTEAFCMAIV---- 288
Cdd:cd03794   236 LEAAERL-KRRPDIRFLFVGDGDEKERLKELAKARGL-DNVTFLGRVPKEEVPELLSAADVGLVPLKDNPANRGSSpskl 313

                         330       340
                  ....*....|....*....|..
gi 1812348123 289 -EGASCGLQVVSTRVGGIPEVL 309
Cdd:cd03794   314 fEYMAAGKPILASDDGGSDLAV 335
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 139-319 1.24e-12

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 68.63  E-value: 1.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 139 LTVSLCDTNHIVcvsytSKENT---VLRAALNPEIVSVIPNAVDPTDFTPDPSQRPP---------DRITIVVISRLVYR 206
Cdd:cd04951   126 LTDFLCDITTNV-----SREALdefIAKKAFSKNKSVPVYNGIDLNKFKKDINVRLKirnklnlknDEFVILNVGRLTEA 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 207 KGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEEVREKYQLHDRVRLLGAleHKDVRGVLVQGHIFLNTSLTEAFCMA 286
Cdd:cd04951   201 KDYPNLLLAISELILSKNDFKLLIAGDGPLRNELERLICNLNLVDRVILLGQ--ISNISEYYNAADLFVLSSEWEGFGLV 278

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1812348123 287 IVEGASCGLQVVSTRVGGIPEVLP--EDLITLCEP 319
Cdd:cd04951   279 VAEAMACERPVVATDAGGVAEVVGdhNYVVPVSDP 313
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 168-309 2.58e-12

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 68.52  E-value: 2.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 168 PEIVSVIPNAVDPTDFTPDPSQRP-PDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHF-LIGGEGPKRLVLEEVRE 245
Cdd:cd03813   266 PDKTRVIPNGIDIQRFAPAREERPeKEPPVVGLVGRVVPIKDVKTFIRAFKLVRRAMPDAEGwLIGPEDEDPEYAQECKR 345

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1812348123 246 KYQ---LHDRVRLLGALEHKDVrgvLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVL 309
Cdd:cd03813   346 LVAslgLENKVKFLGFQNIKEY---YPKLGLLVLTSISEGQPLVILEAMASGVPVVATDVGSCRELI 409
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 193-332 4.37e-12

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 67.49  E-value: 4.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 193 DRITIVVISRLVYRKGIDLLGGIIPELCLKHPDL-----HflIGGeGPKRLVLEEVREKYQLHDRVRLLGALEHKDVRGV 267
Cdd:cd04946   223 GDLRLVSCSSIVPVKRIDLIIETLNSLCVAHPSIciswtH--IGG-GPLKERLEKLAENKLENVKVNFTGEVSNKEVKQL 299

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 268 LVQG--HIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPED---LITLCEPTVRSLCAGLEKVI 332
Cdd:cd04946   300 YKENdvDVFVNVSESEGIPVSIMEAISFGIPVIATNVGGTREIVENEtngLLLDKDPTPNEIVSSIMKFY 369
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 155-302 1.43e-09

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 59.24  E-value: 1.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 155 TSKENTVLRAALNPEI-VSVIPNAVDPTDFTPDPSQrPPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGE 233
Cdd:cd04949   121 TEQQKQDLSERFNKYPpIFTIPVGYVDQLDTAESNH-ERKSNKIITISRLAPEKQLDHLIEAVAKAVKKVPEITLDIYGY 199

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1812348123 234 GPKRLVLEEVREKYQLHDRVRLLGAleHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRV 302
Cdd:cd04949   200 GEEREKLKKLIEELHLEDNVFLKGY--HSNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDV 266
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 42-298 2.15e-09

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 58.84  E-value: 2.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  42 NMGGVESHIYQLSQC-----------------------LIEKGHKVMYNQSTATTCFHSLPLLRCVFVRERITVVHAHSS 98
Cdd:cd03812    10 NVGGIETFLMNLYRKldkskiefdflatsddkgeydeeLEELGGKIFYIPPKKKNIIKYFIKLLKLIKKEKYDIVHVHGS 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  99 FSAMAhdALFHAKTLGL--------NTVFTDHSLFgfADVSSVLTNKLLTVSlcdTNHIVCvsyTSKENTVLRAALNPEI 170
Cdd:cd03812    90 SSNGI--ILLLAAKAGVpvriahshNTKDSSIKLR--KIRKNVLKKLIERLS---TKYLAC---SEDAGEWLFGEVENGK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 171 VSVIPNAVDPTDFTPDPSQR--------PPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKRLVLEE 242
Cdd:cd03812   160 FKVIPNGIDIEKYKFNKEKRrkrrklliLEDKLVLGHVGRFNEQKNHSFLIDIFEELKKKNPNVKLVLVGEGELKEKIKE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1812348123 243 -VREKyQLHDRVRLLGalEHKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVV 298
Cdd:cd03812   240 kVKEL-GLEDKVIFLG--FRNDVSEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCL 293
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 171-309 2.53e-08

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 55.42  E-value: 2.53e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 171 VSVIPNAVDPTDFTPDPSQR-------PPDRITIVVISRLV--YRKGIDLLggiIPELCL--KHPDLHFLIGGEGPKRLV 239
Cdd:cd03825   163 VVVIPNGIDTEIFAPVDKAKarkrlgiPQDKKVILFGAESVtkPRKGFDEL---IEALKLlaTKDDLLLVVFGKNDPQIV 239

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1812348123 240 LE--EVREKYQLHDRVRLLGALEHKDVrgvlvqghiFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVL 309
Cdd:cd03825   240 ILpfDIISLGYIDDDEQLVDIYSAADL---------FVHPSLADNLPNTLLEAMACGTPVVAFDTGGSPEIV 302
PRK15484 PRK15484
lipopolysaccharide N-acetylglucosaminyltransferase;
171-366 9.68e-08

lipopolysaccharide N-acetylglucosaminyltransferase;


Pssm-ID: 185381 [Multi-domain]  Cd Length: 380  Bit Score: 53.64  E-value: 9.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 171 VSVIPNAVDP----TDFTPDPSQR---PPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGE------GPKR 237
Cdd:PRK15484  163 ISIVPNGFCLetyqSNPQPNLRQQlniSPDETVLLYAGRISPDKGILLLMQAFEKLATAHSNLKLVVVGDptasskGEKA 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 238 LVLEEVRE-KYQLHDRVRLLGALE----HKDVRgvlVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIPEVLPED 312
Cdd:PRK15484  243 AYQKKVLEaAKRIGDRCIMLGGQPpekmHNYYP---LADLVVVPSQVEEAFCMVAVEAMAAGKPVLASTKGGITEFVLEG 319

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1812348123 313 lIT---LCEP-TVRSLCAGLEKVIAKqrsgsvPFPTSIHSRVKNL----YTWKNVAERTERV 366
Cdd:PRK15484  320 -ITgyhLAEPmTSDSIISDINRTLAD------PELTQIAEQAKDFvfskYSWEGVTQRFEEQ 374
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 173-306 2.52e-05

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 46.16  E-value: 2.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 173 VIPNAVDPTD-----FTPDPSQR--------PPDRITIVVISRLVYRKGIDLLGGIIPELCLKHPDLHFLIGGEGPKR-- 237
Cdd:cd03792   163 YIPPSIDPLSgknkdLSPADIRYylekpfviDPERPYILQVARFDPSKDPLGVIDAYKLFKRRAEEPQLVICGHGAVDdp 242

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812348123 238 ---LVLEEVREKYQLHDRVRLLGALE-HKDVRGVLVQGHIFLNTSLTEAFCMAIVEGASCGLQVVSTRVGGIP 306
Cdd:cd03792   243 egsVVYEEVMEYAGDDHDIHVLRLPPsDQEINALQRAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIP 315
GlgA COG0297
Glycogen synthase [Carbohydrate transport and metabolism];
192-255 4.18e-05

Glycogen synthase [Carbohydrate transport and metabolism];


Pssm-ID: 440066 [Multi-domain]  Cd Length: 476  Bit Score: 45.85  E-value: 4.18e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1812348123 192 PDRITIVVISRLVYRKGIDLLGGIIPELcLKHpDLHFLIGGEGPKRLV--LEEVREKYqlHDRVRL 255
Cdd:COG0297   293 PDAPLIGMVSRLTEQKGLDLLLEALDEL-LEE-DVQLVVLGSGDPEYEeaFRELAARY--PGRVAV 354
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 171-309 6.44e-05

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 45.05  E-value: 6.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 171 VSVIPNAVDPTDFTPDPSQRPP-DRITIVVISRLV----------YRkGIDLLGGIIPELCLKHPDLHFLI-GGEG---- 234
Cdd:cd03818   181 ISVIHDGVDTDRLAPDPAARLRlLNGTELKAGDPVityvarnlepYR-GFHVFMRALPRIQARRPDARVVVvGGDGvsyg 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 235 --PKRL------VLEEVREKyqlHDRVRLLGALEHKDVRGVL--VQGHIFL------NTSLTEAfcMAivegasCGLQVV 298
Cdd:cd03818   260 spPPDGgswkqkMLAELGVD---LERVHFVGKVPYDQYVRLLqlSDAHVYLtypfvlSWSLLEA--MA------CGCPVI 328

                         170
                  ....*....|.
gi 1812348123 299 STRVGGIPEVL 309
Cdd:cd03818   329 GSDTAPVREVI 339
GT5_Glycogen_synthase_DULL1-like cd03791
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ...
 192-255 7.28e-05

Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.


Pssm-ID: 340822 [Multi-domain]  Cd Length: 474  Bit Score: 44.86  E-value: 7.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1812348123 192 PDRITIVVISRLVYRKGIDLLGGIIPELCLKhpDLHFLIGGEGPKRL--VLEEVREKYqlHDRVRL 255
Cdd:cd03791   292 PDAPLFGFVGRLTEQKGVDLILDALPELLEE--GGQLVVLGSGDPEYeqAFRELAERY--PGKVAV 353
GT4_mannosyltransferase-like cd03822
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ...
 87-367 7.39e-05

mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.


Pssm-ID: 340849 [Multi-domain]  Cd Length: 370  Bit Score: 44.68  E-value: 7.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123  87 RERITVVHAHSSFSAMAHDALFHA----KTLGLNTVFTDHSLFGFADVSSVLTNKLltVSLCDTNHIVCVSYTSKENTVL 162
Cdd:cd03822    73 FKKPDVVHIQHEFGIFGGKYGLYAlgllLHLRIPVITTLHTVLDLSDPGKQALKVL--FRIATLSERVVVMAPISRFLLV 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 163 RAALNP-EIVSVIPNAVDPTDFTPDPS---QRPPDRITIVVISRLVYR-KGIDLLGGIIPELCLKHPDLHFLIGGE---G 234
Cdd:cd03822   151 RIKLIPaVNIEVIPHGVPEVPQDPTTAlkrLLLPEGKKVILTFGFIGPgKGLEILLEALPELKAEFPDVRLVIAGElhpS 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 235 PKRLVLEEVREKYQ----LHDRVRL-LGALEHKDV------RGVLVQGHIFLNTSLTEAFCMAIvegaSCGLQVVSTRVG 303
Cdd:cd03822   231 LARYEGERYRKAAIeelgLQDHVDFhNNFLPEEEVpryisaADVVVLPYLNTEQSSSGTLSYAI----ACGKPVISTPLR 306

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1812348123 304 GIPEVLPEDLITLCEP-TVRSLCAGLEKVIakqrsgSVPFPTSIHSRVKNLY----TWKNVAERTERVY 367
Cdd:cd03822   307 HAEELLADGRGVLVPFdDPSAIAEAILRLL------EDDERRQAIAERAYAYaramTWESIADRYLRLF 369
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 168-303 2.58e-04

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 43.38  E-value: 2.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812348123 168 PEIVSVIPNAVDPTDFTPDPSQRPPDRITIV-VISRLVYRKGIDLLGGIIPELCLKHPDLH-FLIGGEGPKRLVLEEVR- 244
Cdd:NF038011  279 PERTRVIPNGIDLPRLAPLRAQRPAGIPPVVgLIGRVVPIKDIKTFIRAMRTVVRAMPEAEgWIVGPEEEDPAYAAECRs 358

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1812348123 245 --EKYQLHDRVRLLGaleHKDVRGVLVQ-GHIFLnTSLTEAFCMAIVEGASCGLQVVSTRVG 303
Cdd:NF038011  359 lvASLGLQDKVKFLG---FQKIDDLLPQvGLMVL-SSISEALPLVVLEAFAAGVPVVTTDVG 416
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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