NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1806705737|ref|XP_032229282|]
View 

aspartyl/asparaginyl beta-hydroxylase isoform X2 [Nematostella vectensis]

Protein Classification

similar to aspartyl beta-hydroxylase, isoform A( domain architecture ID 11420810)

protein similar to aspartyl beta-hydroxylase, isoform A

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Asp_Arg_Hydrox pfam05118
Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases ...
 381-534 1.56e-78

Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.


:

Pssm-ID: 461552  Cd Length: 157  Bit Score: 243.71  E-value: 1.56e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 381 EKNWHVIREEGLAIMDQKSGGFIPEEENLRDTGD--WKQFTLYQQGRKQVANCRKTPRTCAIMDTIP-DAIGCKRGQVKF 457
Cdd:pfam05118   1 EANWQVIRDELLALLKQEEGLPPYEEEALDDFGDigWKTFYLYAYGARLPENCALCPKTAALLEQPGvKASGCPRGQAMF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1806705737 458 SVMLPGTHVWPHTGPTNCRLRSHLGLVIPDNVFIRVGTATKTWQEGKVIIIDDSIDHEVWHNGTSFRLIFIVDFWHP 534
Cdd:pfam05118  81 SRLQPGTHIPPHRGPTNGRLRCHLGLVVPPGCRIRVGGETRTWREGECLLFDDSFEHEAWNETDEPRVVLLVDVWRP 157
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
134-299 7.23e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 97.77  E-value: 7.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 134 NKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADqrrsndlLQECIQNYRKIPEL-PDCPAelkkiALV 212
Cdd:COG0457    13 NLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGR-------YEEALADYEQALELdPDDAE-----ALN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 213 RMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHY 292
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160


                  ....*..
gi 1806705737 293 QEAIPFL 299
Cdd:COG0457   161 EEALELL 167
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 248-353 3.56e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 3.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 248 LGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFLiEGVTSGDPgaDDGRFYFHLGDALTRTG 327
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIH-QKLLERDP--DRAEALLELAQDYLKAG 90

                          90       100
                  ....*....|....*....|....*.
gi 1806705737 328 KPEEANKWYADAARKGIFLSAMQRSL 353
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLL 116
 
Name Accession Description Interval E-value
Asp_Arg_Hydrox pfam05118
Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases ...
 381-534 1.56e-78

Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.


Pssm-ID: 461552  Cd Length: 157  Bit Score: 243.71  E-value: 1.56e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 381 EKNWHVIREEGLAIMDQKSGGFIPEEENLRDTGD--WKQFTLYQQGRKQVANCRKTPRTCAIMDTIP-DAIGCKRGQVKF 457
Cdd:pfam05118   1 EANWQVIRDELLALLKQEEGLPPYEEEALDDFGDigWKTFYLYAYGARLPENCALCPKTAALLEQPGvKASGCPRGQAMF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1806705737 458 SVMLPGTHVWPHTGPTNCRLRSHLGLVIPDNVFIRVGTATKTWQEGKVIIIDDSIDHEVWHNGTSFRLIFIVDFWHP 534
Cdd:pfam05118  81 SRLQPGTHIPPHRGPTNGRLRCHLGLVVPPGCRIRVGGETRTWREGECLLFDDSFEHEAWNETDEPRVVLLVDVWRP 157
LpxO2 COG3555
Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, ...
 376-542 1.16e-54

Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442776  Cd Length: 220  Bit Score: 183.92  E-value: 1.16e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 376 ELRKLEKNWHVIREEGLAIMDQKSG-----GFIPEEENLRDTGDWKQFTLYQQGRKQVANCRKTPRTCAIMDTIPdaiGC 450
Cdd:COG3555    19 WLAELEANWPTIRAELLALLAEIEAlppyhDISFDQANIFFDRGWKRFYLYWYGERHPSNCALCPKTAALLEQIP---GV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 451 KrgQVKFSVMLPGTHVWPHTGPTNCRLRSHLGLVIP--DNVFIRVGTATKTWQEGKVIIIDDSIDHEVWHNGTSFRLIFI 528
Cdd:COG3555    96 K--AAMFSILPPGKHIPPHRGPYNGRLRYHLGLIVPndDRCRIRVDGETYSWREGEAVLFDDTYEHEAWNDTDETRVVLF 173

                         170
                  ....*....|....
gi 1806705737 529 VDFWHPELTPRQRA 542
Cdd:COG3555   174 CDVWRPMLSPWERA 187
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
134-299 7.23e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 97.77  E-value: 7.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 134 NKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADqrrsndlLQECIQNYRKIPEL-PDCPAelkkiALV 212
Cdd:COG0457    13 NLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGR-------YEEALADYEQALELdPDDAE-----ALN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 213 RMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHY 292
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160


                  ....*..
gi 1806705737 293 QEAIPFL 299
Cdd:COG0457   161 EEALELL 167
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 75-273 1.15e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.79  E-value: 1.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737  75 RTQTQNK--------LKDTVKEEPVSSTNKKSKIKPQNRMSQESKANKE-KKTVDPKNTYDRSIakeLNKGMALLDKQKV 145
Cdd:TIGR02917 609 RAQLAAGdlnkavssFKKLLALQPDSALALLLLADAYAVMKNYAKAITSlKRALELKPDNTEAQ---IGLAQLLLAAKRT 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 146 EDALRYFRQLVEEHPKSPL--ALYGKAVAldkladqrRSNDLlQECIQNYRKIPELpdcpaELKKIALVRMAGRLSFLGR 223
Cdd:TIGR02917 686 ESAKKIAKSLQKQHPKAALgfELEGDLYL--------RQKDY-PAAIQAYRKALKR-----APSSQNAIKLHRALLASGN 751

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1806705737 224 MRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNP 273
Cdd:TIGR02917 752 TAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 133-173 6.76e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.17  E-value: 6.76e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1806705737 133 LNKGMALLDKQKVEDALRYFRQLVEEHPKSPL---ALYGKAVAL 173
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPDaaaALLLLGLAA 44
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 248-353 3.56e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 3.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 248 LGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFLiEGVTSGDPgaDDGRFYFHLGDALTRTG 327
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIH-QKLLERDP--DRAEALLELAQDYLKAG 90

                          90       100
                  ....*....|....*....|....*.
gi 1806705737 328 KPEEANKWYADAARKGIFLSAMQRSL 353
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLL 116
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 248-354 9.55e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 9.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 248 LGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPfLIEGVTSGDpgaDDGR--FYFHLGDALTR 325
Cdd:TIGR02917  62 LGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLD-ELPGKTLLD---DEGAaeLLALRGLAYLG 137

                          90       100
                  ....*....|....*....|....*....
gi 1806705737 326 TGKPEEANKWYADAarkgifLSAMQRSLY 354
Cdd:TIGR02917 138 LGQLELAQKSYEQA------LAIDPRSLY 160
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 222-279 2.08e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 2.08e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1806705737 222 GRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAK 279
Cdd:cd24142    14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEK 71
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 282-343 6.80e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 35.39  E-value: 6.80e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1806705737 282 LGFALKVQLHYQEAIPFLIEGVTSGDPGADDGRFYFHLGDALTRTGKPEEANKWYADAARKG 343
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAALARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAA 64
 
Name Accession Description Interval E-value
Asp_Arg_Hydrox pfam05118
Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases ...
 381-534 1.56e-78

Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.


Pssm-ID: 461552  Cd Length: 157  Bit Score: 243.71  E-value: 1.56e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 381 EKNWHVIREEGLAIMDQKSGGFIPEEENLRDTGD--WKQFTLYQQGRKQVANCRKTPRTCAIMDTIP-DAIGCKRGQVKF 457
Cdd:pfam05118   1 EANWQVIRDELLALLKQEEGLPPYEEEALDDFGDigWKTFYLYAYGARLPENCALCPKTAALLEQPGvKASGCPRGQAMF 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1806705737 458 SVMLPGTHVWPHTGPTNCRLRSHLGLVIPDNVFIRVGTATKTWQEGKVIIIDDSIDHEVWHNGTSFRLIFIVDFWHP 534
Cdd:pfam05118  81 SRLQPGTHIPPHRGPTNGRLRCHLGLVVPPGCRIRVGGETRTWREGECLLFDDSFEHEAWNETDEPRVVLLVDVWRP 157
LpxO2 COG3555
Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, ...
 376-542 1.16e-54

Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442776  Cd Length: 220  Bit Score: 183.92  E-value: 1.16e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 376 ELRKLEKNWHVIREEGLAIMDQKSG-----GFIPEEENLRDTGDWKQFTLYQQGRKQVANCRKTPRTCAIMDTIPdaiGC 450
Cdd:COG3555    19 WLAELEANWPTIRAELLALLAEIEAlppyhDISFDQANIFFDRGWKRFYLYWYGERHPSNCALCPKTAALLEQIP---GV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 451 KrgQVKFSVMLPGTHVWPHTGPTNCRLRSHLGLVIP--DNVFIRVGTATKTWQEGKVIIIDDSIDHEVWHNGTSFRLIFI 528
Cdd:COG3555    96 K--AAMFSILPPGKHIPPHRGPYNGRLRYHLGLIVPndDRCRIRVDGETYSWREGEAVLFDDTYEHEAWNDTDETRVVLF 173

                         170
                  ....*....|....
gi 1806705737 529 VDFWHPELTPRQRA 542
Cdd:COG3555   174 CDVWRPMLSPWERA 187
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
134-299 7.23e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 97.77  E-value: 7.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 134 NKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADqrrsndlLQECIQNYRKIPEL-PDCPAelkkiALV 212
Cdd:COG0457    13 NLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGR-------YEEALADYEQALELdPDDAE-----ALN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 213 RMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHY 292
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160


                  ....*..
gi 1806705737 293 QEAIPFL 299
Cdd:COG0457   161 EEALELL 167
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
156-411 2.98e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 90.07  E-value: 2.98e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 156 VEEHPKSPLALYGKAVALDKLADqrrsndlLQECIQNYRKIPEL-PDCPAELKKIALVRMAgrlsfLGRMRQAAAALEKV 234
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGR-------YEEAIEDYEKALELdPDDAEALYNLGLAYLR-----LGRYEEALADYEQA 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 235 ASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFLIEGVTSgDPgaDDGR 314
Cdd:COG0457    69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL-DP--DDAD 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 315 FYFHLGDALTRTGKPEEANKWYADAARKGIFLSAMQRSLYNADTSLTAKPWWTPEETGYAEELRKLEKNWHVIREEGLAI 394
Cdd:COG0457   146 ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLL 225

                         250
                  ....*....|....*..
gi 1806705737 395 MDQKSGGFIPEEENLRD 411
Cdd:COG0457   226 ALALLLALRLAALALYQ 242
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 133-342 4.19e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.70  E-value: 4.19e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 133 LNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNYRKIPElpdcpaelkkiALV 212
Cdd:COG2956    46 LALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE-----------ALR 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 213 RMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHY 292
Cdd:COG2956   115 LLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDY 194

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1806705737 293 QEAIPFLIEGVTSgDPgaDDGRFYFHLGDALTRTGKPEEANKWYADAARK 342
Cdd:COG2956   195 EEAIAALERALEQ-DP--DYLPALPRLAELYEKLGDPEEALELLRKALEL 241
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 210-342 1.43e-16

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 76.38  E-value: 1.43e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 210 ALVRMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQ 289
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1806705737 290 LHYQEAIPFLiEGVTSGDPgaDDGRFYFHLGDALTRTGKPEEANKWYADAARK 342
Cdd:COG4783    86 GDYDEALALL-EKALKLDP--EHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 133-342 3.77e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 78.62  E-value: 3.77e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 133 LNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYgkavALDKLADQRRSNDLLQECIQNYRKIpelpdcpAELKKIALV 212
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHL----ALGNLYRRRGEYDRAIRIHQKLLER-------DPDRAEALL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 213 RMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHY 292
Cdd:COG2956    81 ELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDY 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1806705737 293 QEAIPFLIEGVTSgDPgaDDGRFYFHLGDALTRTGKPEEANKWYADAARK 342
Cdd:COG2956   161 DEAIEALEKALKL-DP--DCARALLLLAELYLEQGDYEEAIAALERALEQ 207
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 138-318 3.00e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 78.88  E-value: 3.00e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 138 ALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADqrrsndlLQECIQNYRKIPEL-PDCPAelkkiALVRMAG 216
Cdd:COG3914    87 LLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGR-------LEEALAALRRALALnPDFAE-----AYLNLGE 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 217 RLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAI 296
Cdd:COG3914   155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYD 234

                         170       180
                  ....*....|....*....|..
gi 1806705737 297 PFLIEGVTSGDPGADDGRFYFH 318
Cdd:COG3914   235 RFEELLAALARGPSELSPFALL 256
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
125-270 2.80e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 72.73  E-value: 2.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 125 YDRSIAKE-------LNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADqrrsndlLQECIQNYRKIP 197
Cdd:COG0457    31 YEKALELDpddaealYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGR-------YEEALEDYDKAL 103

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1806705737 198 EL-PDCPAELKKIALVRMAgrlsfLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLK 270
Cdd:COG0457   104 ELdPDDAEALYNLGLALLE-----LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 137-339 6.80e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.64  E-value: 6.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 137 MALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNYRKIPELPDCPAELKKIALVRM-- 214
Cdd:COG3914     5 ALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLEla 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 215 AGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQE 294
Cdd:COG3914    85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1806705737 295 AIPFLiEGVTSGDPgaDDGRFYFHLGDALTRTGKPEEANKWYADA 339
Cdd:COG3914   165 AIAAL-RRALELDP--DNAEALNNLGNALQDLGRLEEAIAAYRRA 206
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 213-299 2.07e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 67.34  E-value: 2.07e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 213 RMAGRLSF-LGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLH 291
Cdd:COG4235    21 LLLGRAYLrLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGD 100


                  ....*...
gi 1806705737 292 YQEAIPFL 299
Cdd:COG4235   101 YAEAIAAW 108
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 132-273 2.76e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.14  E-value: 2.76e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 132 ELNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNYRKIPElpdcpaelkkiAL 211
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPE-----------AR 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1806705737 212 VRMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNP 273
Cdd:COG4783    76 LNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 164-299 1.46e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 65.75  E-value: 1.46e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 164 LALYGKAVALDKLADQRRSNDLLQECIQNYRKIPELPDCPAELKKIALVRMAGRLSF--LGRMRQAAAALEKVASLFPSD 241
Cdd:COG5010     8 DRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYnkLGDFEESLALLEQALQLDPNN 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1806705737 242 VKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFL 299
Cdd:COG5010    88 PELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAAL 145
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 111-301 2.21e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 2.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 111 KANKEKKTVDPKNTYDRSIAKELnkGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADqrrsndlLQECI 190
Cdd:COG2956    94 RAEELLEKLLELDPDDAEALRLL--AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD-------YDEAI 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 191 QNYRKIPEL-PDCPAELKKIALVRMAgrlsfLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVL 269
Cdd:COG2956   165 EALEKALKLdPDCARALLLLAELYLE-----QGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL 239

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1806705737 270 KLNPGSgFAKSHLGFALKVQLHYQEAIPFLIE 301
Cdd:COG2956   240 ELDPSD-DLLLALADLLERKEGLEAALALLER 270
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 226-332 4.08e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 63.49  E-value: 4.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 226 QAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPfLIEGVTS 305
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEE-LLERALA 79

                          90       100
                  ....*....|....*....|....*..
gi 1806705737 306 GDPgaDDGRFYFHLGDALTRTGKPEEA 332
Cdd:COG4235    80 LDP--DNPEALYLLGLAAFQQGDYAEA 104
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 137-240 5.46e-11

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 59.62  E-value: 5.46e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 137 MALLDKQKVEDALRYFRQLVEEHPKSPL---ALYGKAVALDKLADQRRSNDLLQECIQNYRKIPELPDcpaelkkiALVR 213
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYPNSPLapdALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPD--------ALLK 72

                          90       100
                  ....*....|....*....|....*..
gi 1806705737 214 MAGRLSFLGRMRQAAAALEKVASLFPS 240
Cdd:COG1729    73 LGLSYLELGDYDKARATLEELIKKYPD 99
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
252-342 1.99e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.49  E-value: 1.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 252 YLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFliEGVTSGDPgaDDGRFYFHLGDALTRTGKPEE 331
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL--EKALKLDP--NNAEALLNLAELLLELGDYDE 77

                          90
                  ....*....|.
gi 1806705737 332 ANKWYADAARK 342
Cdd:COG3063    78 ALAYLERALEL 88
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 204-341 2.30e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 59.20  E-value: 2.30e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 204 AELKKIALVRMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMY---GNNQDAEKVFKKVLKLNPGSGFAKS 280
Cdd:COG5010    13 YLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYnklGDFEESLALLEQALQLDPNNPELYY 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1806705737 281 HLGFALKVQLHYQEAIPFLIEGVTSgDPgaDDGRFYFHLGDALTRTGKPEEANKWYADAAR 341
Cdd:COG5010    93 NLALLYSRSGDKDEAKEYYEKALAL-SP--DNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 147-275 9.20e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.94  E-value: 9.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 147 DALRYFRQLVEEHPKSPLALYgkavaldKLADQRRSNDLLQECIQNYRKIPEL-PDCPAelkkiALVRMAGRLSFLGRMR 225
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWL-------LLGRAYLRLGRYDEALAAYEKALRLdPDNAD-----ALLDLAEALLAAGDTE 68

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1806705737 226 QAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGS 275
Cdd:COG4235    69 EAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 240-342 1.33e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 1.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 240 SDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFLIEGVtSGDPgaDDGRFYFHL 319
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEAL-ELDP--DEPEARLNL 78

                          90       100
                  ....*....|....*....|...
gi 1806705737 320 GDALTRTGKPEEANKWYADAARK 342
Cdd:COG4783    79 GLALLKAGDYDEALALLEKALKL 101
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 125-273 3.22e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.12  E-value: 3.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 125 YDRSIAKELNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLadqrrsndllqeciqnyrkipelpdcpa 204
Cdd:COG5010    50 LAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRS---------------------------- 101

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1806705737 205 elkkialvrmagrlsflGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNP 273
Cdd:COG5010   102 -----------------GDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
221-299 6.33e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 53.25  E-value: 6.33e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1806705737 221 LGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKvFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFL 299
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYL 82
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 75-273 1.15e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.79  E-value: 1.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737  75 RTQTQNK--------LKDTVKEEPVSSTNKKSKIKPQNRMSQESKANKE-KKTVDPKNTYDRSIakeLNKGMALLDKQKV 145
Cdd:TIGR02917 609 RAQLAAGdlnkavssFKKLLALQPDSALALLLLADAYAVMKNYAKAITSlKRALELKPDNTEAQ---IGLAQLLLAAKRT 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 146 EDALRYFRQLVEEHPKSPL--ALYGKAVAldkladqrRSNDLlQECIQNYRKIPELpdcpaELKKIALVRMAGRLSFLGR 223
Cdd:TIGR02917 686 ESAKKIAKSLQKQHPKAALgfELEGDLYL--------RQKDY-PAAIQAYRKALKR-----APSSQNAIKLHRALLASGN 751

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1806705737 224 MRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNP 273
Cdd:TIGR02917 752 TAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 140-338 1.99e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.40  E-value: 1.99e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 140 LDKQKVEDALRYFRQLVEEHPKSPLALygkaVALDKLADQRRSNDllqECIQNYRKIPELpDCPAELKKIALvrmAGRLS 219
Cdd:TIGR02917 510 IQEGNPDDAIQRFEKVLTIDPKNLRAI----LALAGLYLRTGNEE---EAVAWLEKAAEL-NPQEIEPALAL---AQYYL 578

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 220 FLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFL 299
Cdd:TIGR02917 579 GKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSL 658

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1806705737 300 IEGVTSgDPGADDGRFYfhLGDALTRTGKPEEANKWYAD 338
Cdd:TIGR02917 659 KRALEL-KPDNTEAQIG--LAQLLLAAKRTESAKKIAKS 694
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 133-241 3.05e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.50  E-value: 3.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 133 LNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNYrkipelPDCPAELKKIALV 212
Cdd:COG4783    42 ALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLD------PEHPEAYLRLARA 115

                          90       100
                  ....*....|....*....|....*....
gi 1806705737 213 RMAgrlsfLGRMRQAAAALEKVASLFPSD 241
Cdd:COG4783   116 YRA-----LGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 226-343 4.61e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 4.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 226 QAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFLIEGVts 305
Cdd:COG2956    26 KAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLL-- 103

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1806705737 306 gDPGADDGRFYFHLGDALTRTGKPEEANKWYADAARKG 343
Cdd:COG2956   104 -ELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLG 140
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 133-241 5.23e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.55  E-value: 5.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 133 LNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNYrkipelPDCPAelkkiALV 212
Cdd:COG4235    21 LLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD------PDNPE-----ALY 89

                          90       100
                  ....*....|....*....|....*....
gi 1806705737 213 RMAGRLSFLGRMRQAAAALEKVASLFPSD 241
Cdd:COG4235    90 LLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
172-384 7.06e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.38  E-value: 7.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 172 ALDKLADQRRSNDLLqecIQNYRKIPELPDCPAELKKIALVRMAGRLSFLGRMRQAAAALEKVASLF-----PSDVKVLK 246
Cdd:COG4785     1 LYALALALLLALALA---AAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDralalPDLAQLYY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 247 DLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFLIEGVTSgDPgaDDGRFYFHLGDALTRT 326
Cdd:COG4785    78 ERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALEL-DP--DYAYAYLNRGIALYYL 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1806705737 327 GKPEEAnkwYADaarkgiFLSAMQrsLYNADTSLTAKPWWTPEETGYAEELRKLEKNW 384
Cdd:COG4785   155 GRYELA---IAD------LEKALE--LDPNDPERALWLYLAERKLDPEKALALLLEDW 201
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 139-341 1.84e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 52.99  E-value: 1.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 139 LLDKQKVEDALRYFRQLVEEHPKSPLAL------Y---GKAVALDKLADQ-RRSN----------------DLLQECIQN 192
Cdd:COG3071    95 LLDQGQAEQALATLEALRAGAPRHPQVLrlllqaYrqlGDWEELLELLPAlRKHKalsaeeaqalerraylGLLRQAARD 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 193 YRKIPE----LPDcpAELKKIALV-RMAGRLSFLGRMRQAAAALEKVASLFPSDvkvlkDLGVQY--LMYGNNQDAEKVF 265
Cdd:COG3071   175 AEALKAlwkaLPR--AERRDPELAaAYARALIALGDHDEAERLLREALKRQWDP-----RLVRLYgrLQGGDPAKQLKRA 247

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1806705737 266 KKVLKLNPGSGFAKSHLG-FALKVQLhYQEAIPFLiEGVTSGDPGADDgrfYFHLGDALTRTGKPEEANKWYADAAR 341
Cdd:COG3071   248 EKWLKKHPNDPDLLLALGrLCLRNQL-WGKAREYL-EAALALRPSAEA---YAELARLLEQLGDPEEAAEHYRKALA 319
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
124-296 8.49e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.91  E-value: 8.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 124 TYDRSIAKELNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDllqeciqnyrKIPELPDCP 203
Cdd:COG4785     1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAE----------RIDRALALP 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 204 aelKKIALVRMAGRLSF-LGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHL 282
Cdd:COG4785    71 ---DLAQLYYERGVAYDsLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNR 147

                         170
                  ....*....|....
gi 1806705737 283 GFALKVQLHYQEAI 296
Cdd:COG4785   148 GIALYYLGRYELAI 161
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 136-209 9.37e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 47.68  E-value: 9.37e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1806705737 136 GMALLDKQKVEDALRYFRQLVEEHPKSPL---ALYGKAVALDKLADQRRSNDLLQECIQNYRKIPELPDCPAELKKI 209
Cdd:COG1729    37 GEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDKARATLEELIKKYPDSEAAKEARARLARL 113
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 170-344 1.21e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.15  E-value: 1.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 170 AVALDKLADQRRSNDLL-QECIQNYRKIPELPDCPAELKKIA--LVRMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLK 246
Cdd:COG3914     3 AAALLALAALAAAALLAaAAAAELALAAELEAAALAAALGLAllLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 247 DLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFLiEGVTSGDPgaDDGRFYFHLGDALTRT 326
Cdd:COG3914    83 LAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAAL-RRALALNP--DFAEAYLNLGEALRRL 159

                         170
                  ....*....|....*...
gi 1806705737 327 GKPEEAnkwyADAARKGI 344
Cdd:COG3914   160 GRLEEA----IAALRRAL 173
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 127-341 2.03e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 127 RSIAKELNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKA----------VALDKLADQRRSNdllqeciqnyrki 196
Cdd:TIGR02917 225 NNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKAlvdfqkknyeDARETLQDALKSA------------- 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 197 PELPdcPAELkkialvrMAGRLSF-LGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGS 275
Cdd:TIGR02917 292 PEYL--PALL-------LAGASEYqLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDD 362

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1806705737 276 GFAKSHLGFALKVQLHYQEAIpFLIEGVTSGDPgaDDGRFYFHLGDALTRTGKPEEANKWYADAAR 341
Cdd:TIGR02917 363 PAALSLLGEAYLALGDFEKAA-EYLAKATELDP--ENAAARTQLGISKLSQGDPSEAIADLETAAQ 425
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
138-273 1.00e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.39  E-value: 1.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 138 ALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALdkladqrrsndllqeciqnyrkipelpdcpaelkkialvRMAGR 217
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLL---------------------------------------LEQGR 41

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1806705737 218 LsflgrmrQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNP 273
Cdd:COG3063    42 Y-------DEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 135-296 1.32e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 135 KGMALLDKQKVEDALRYFRQLVEEHPKSPLALYgkavaldKLADQRRSNDLLQECIQNYRKIPEL-PD-CPAELKKIALV 212
Cdd:TIGR02917 607 LGRAQLAAGDLNKAVSSFKKLLALQPDSALALL-------LLADAYAVMKNYAKAITSLKRALELkPDnTEAQIGLAQLL 679

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 213 RMAGRL---------------------SFLGR--MRQ-----AAAALEKVASLFPSDVKVLKdLGVQYLMYGNNQDAEKV 264
Cdd:TIGR02917 680 LAAKRTesakkiakslqkqhpkaalgfELEGDlyLRQkdypaAIQAYRKALKRAPSSQNAIK-LHRALLASGNTAEAVKT 758

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1806705737 265 FKKVLKLNPGSGFAKSHLGFALKVQLHYQEAI 296
Cdd:TIGR02917 759 LEAWLKTHPNDAVLRTALAELYLAQKDYDKAI 790
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 250-342 1.49e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.21  E-value: 1.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 250 VQYLMYGNNQDAEKVFKKVLKLNPGSGFAKS---HLGFALKVQLHYQEAIPFLIEGVTSGDPGADDGRFYFHLGDALTRT 326
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLEL 80

                          90
                  ....*....|....*.
gi 1806705737 327 GKPEEANKWYADAARK 342
Cdd:COG1729    81 GDYDKARATLEELIKK 96
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 120-342 1.67e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 1.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 120 DPKNTYDRSIAkelnkGMALLDKQKVEDALRYFRQLVEEHPKSPlALYGKaVALDKLADQRRSndllqECIQNYRKI--- 196
Cdd:TIGR02917 359 DPDDPAALSLL-----GEAYLALGDFEKAAEYLAKATELDPENA-AARTQ-LGISKLSQGDPS-----EAIADLETAaql 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 197 -PELPDcpAELkkiALVrmagrLSFL--GRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNP 273
Cdd:TIGR02917 427 dPELGR--ADL---LLI-----LSYLrsGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEP 496

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1806705737 274 GSGFAKSHLgfalkVQLHYQEAIPFL----IEGVTSGDPGadDGRFYFHLGDALTRTGKPEEANKWYADAARK 342
Cdd:TIGR02917 497 DFFPAAANL-----ARIDIQEGNPDDaiqrFEKVLTIDPK--NLRAILALAGLYLRTGNEEEAVAWLEKAAEL 562
tol_pal_ybgF TIGR02795
tol-pal system protein YbgF; Members of this protein family are the product of one of seven ...
 139-240 2.44e-05

tol-pal system protein YbgF; Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.


Pssm-ID: 188247 [Multi-domain]  Cd Length: 117  Bit Score: 43.81  E-value: 2.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 139 LLDKQKVEDALRYFRQLVEEHPKSPL---ALYGKAVALDKLADQRRSNDLLQECIQNYRKIPELPDcpaelkkiALVRMA 215
Cdd:TIGR02795  10 VLKAGDYADAIQAFQAFLKKYPKSTYapnAHYWLGEAYYAQGDYADAAKAFLAVVKKYPKSPKAPD--------ALLKLG 81

                          90       100
                  ....*....|....*....|....*
gi 1806705737 216 GRLSFLGRMRQAAAALEKVASLFPS 240
Cdd:TIGR02795  82 MSLQELGDKEKAKATLQQVIKRYPG 106
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 119-193 5.10e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 5.10e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1806705737 119 VDPKNTYDRsiakeLNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNY 193
Cdd:COG4783    67 LDPDEPEAR-----LNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 133-173 6.76e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.17  E-value: 6.76e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1806705737 133 LNKGMALLDKQKVEDALRYFRQLVEEHPKSPL---ALYGKAVAL 173
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPDaaaALLLLGLAA 44
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
111-301 1.08e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.75  E-value: 1.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 111 KANKEKKTVDPKNTYDRSIAKELNKGMALLDKQKVEDALRYFRqlveeHPKSPLALYGKAVALDKLADqrrsndlLQECI 190
Cdd:COG4785    26 LAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALA-----LPDLAQLYYERGVAYDSLGD-------YDLAI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 191 QNYRKIPEL-PDCPAelkkiALVRMAGRLSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVL 269
Cdd:COG4785    94 ADFDQALELdPDLAE-----AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKAL 168

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1806705737 270 KLNPGSGFAKSHLGFALKvQLHYQEAIPFLIE 301
Cdd:COG4785   169 ELDPNDPERALWLYLAER-KLDPEKALALLLE 199
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
133-270 1.67e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 133 LNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADqrrsndlLQECIQNYRKIPEL-PDCPAelkkiAL 211
Cdd:COG4785    77 YERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGD-------YDAALEDFDRALELdPDYAY-----AY 144

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1806705737 212 VRMAGRLSFLGRMRQAAAALEKVASLFPSDV--------------------KVLKDLGVQYLMYGNNQDAEKVFKKVLK 270
Cdd:COG4785   145 LNRGIALYYLGRYELAIADLEKALELDPNDPeralwlylaerkldpekalaLLLEDWATAYLLQGDTEEARELFKLALA 223
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
125-194 1.77e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.46  E-value: 1.77e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1806705737 125 YDRSIAKE-------LNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNYR 194
Cdd:COG0457    99 YDKALELDpddaealYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175
TPR_19 pfam14559
Tetratricopeptide repeat;
222-275 1.90e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.49  E-value: 1.90e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1806705737 222 GRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGS 275
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDD 55
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 248-353 3.56e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 3.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 248 LGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPFLiEGVTSGDPgaDDGRFYFHLGDALTRTG 327
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIH-QKLLERDP--DRAEALLELAQDYLKAG 90

                          90       100
                  ....*....|....*....|....*.
gi 1806705737 328 KPEEANKWYADAARKGIFLSAMQRSL 353
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLL 116
OM_YfiO TIGR03302
outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a ...
 112-239 5.49e-04

outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274513 [Multi-domain]  Cd Length: 235  Bit Score: 41.77  E-value: 5.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 112 ANKEKKTVDPknTYDRSIAKELNKGMALLDKQKVEDALRYFRQLVEEHPKSPLAlygkAVALDKLAD-QRRSNDLLQ--E 188
Cdd:TIGR03302  18 SSKKKKEADP--VEEWPAEELYEEAKEALDSGDYTEAIKYFEALESRYPFSPYA----EQAQLDLAYaYYKSGDYAEaiA 91

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1806705737 189 CIQNYRKI-PELPDCPAELKKIALVRMAGRLSF---LGRMRQAAAALEKVASLFP 239
Cdd:TIGR03302  92 AADRFIRLhPNHPDADYAYYLRGLSNYNQIDRVdrdQTAAREAFEAFQELIRRYP 146
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 248-354 9.55e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.99  E-value: 9.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 248 LGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFALKVQLHYQEAIPfLIEGVTSGDpgaDDGR--FYFHLGDALTR 325
Cdd:TIGR02917  62 LGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLD-ELPGKTLLD---DEGAaeLLALRGLAYLG 137

                          90       100
                  ....*....|....*....|....*....
gi 1806705737 326 TGKPEEANKWYADAarkgifLSAMQRSLY 354
Cdd:TIGR02917 138 LGQLELAQKSYEQA------LAIDPRSLY 160
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 122-279 1.38e-03

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 40.63  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 122 KNTYDRSIAKELNKGMALLDKQKVEDALRYFRQLVEEHPKSPLA---LYGKAVALDKLADQRRSNDLLQECIQNYRKIPE 198
Cdd:COG4105    25 KALKSWDAEELYEEAKEALEKGDYEKAIKLFEELEPRYPGSPYAeqaQLMLAYAYYKQGDYEEAIAAADRFIKLYPNSPN 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 199 LPDCpaeLKKIALVRMAGRLSF---LGRMRQAAAALEKVASLFP-----SDVKVL----------KDLGV--QYLMYGNN 258
Cdd:COG4105   105 ADYA---YYLRGLSYYEQSPDSdrdQTSTRKAIEAFQELINRYPdseyaEDAKKRidelrdklarKELEVarYYLKRGAY 181

                         170       180
                  ....*....|....*....|.
gi 1806705737 259 QDAEKVFKKVLKLNPGSGFAK 279
Cdd:COG4105   182 VAAINRFQNVLEDYPDTPAVE 202
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 222-279 2.08e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 2.08e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1806705737 222 GRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAK 279
Cdd:cd24142    14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEK 71
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 207-383 2.12e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 2.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 207 KKIALVRMAGRLSFLGRMRQAAAALEKVASLF-PSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGFA 285
Cdd:TIGR02917  89 KNQVLPLLARAYLLQGKFQQVLDELPGKTLLDdEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQL 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 286 LKVQLHYQEAIPfLIEGVTSGDPGADDGrfYFHLGDALTRTGKPEEANKWYADAARKGIFLSAmqrSLYNADTSLTAKPW 365
Cdd:TIGR02917 169 ALAENRFDEARA-LIDEVLTADPGNVDA--LLLKGDLLLSLGNIELALAAYRKAIALRPNNIA---VLLALATILIEAGE 242

                         170
                  ....*....|....*...
gi 1806705737 366 WTPEETgYAEELRKLEKN 383
Cdd:TIGR02917 243 FEEAEK-HADALLKKAPN 259
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 92-279 2.44e-03

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 39.86  E-value: 2.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737  92 SSTNKKSKIKP--------QNRMSQE--SKANKEKKTVDPKNTYDRSIAK-ELNKGMALLDKQKVEDALRYFRQLVEEHP 160
Cdd:COG4105    21 SSFKKALKSWDaeelyeeaKEALEKGdyEKAIKLFEELEPRYPGSPYAEQaQLMLAYAYYKQGDYEEAIAAADRFIKLYP 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 161 KSPL---ALYGKAVALDKLA-----DQ---RRSNDLLQECIQNYRKIPELPDCpaeLKKIALVR--------MAGRLSF- 220
Cdd:COG4105   101 NSPNadyAYYLRGLSYYEQSpdsdrDQtstRKAIEAFQELINRYPDSEYAEDA---KKRIDELRdklarkelEVARYYLk 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1806705737 221 LGRMRQAAAALEKVASLFP---SDVKVLKDLGVQYLMYGNNQDAEKVFkKVLKLN-PGSGFAK 279
Cdd:COG4105   178 RGAYVAAINRFQNVLEDYPdtpAVEEALYLLVEAYYALGRYDEAQDAA-AVLGKNyPDSPYLK 239
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
133-195 3.81e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 3.81e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1806705737 133 LNKGMALLDKQKVEDALRyFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNYRK 195
Cdd:COG3063    30 NNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 133-204 4.13e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.98  E-value: 4.13e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1806705737 133 LNKGMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADqrrsndlLQECIQNYRKIPEL-PDCPA 204
Cdd:COG3914   150 LNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGR-------LEEAIAAYRRALELdPDNAD 215
TPR_1 pfam00515
Tetratricopeptide repeat;
242-273 4.45e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 4.45e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1806705737 242 VKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNP 273
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 136-339 5.21e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.68  E-value: 5.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 136 GMALLDKQKVEDALRYFRQLVEEHPKSPLALYGKAVALDKLADQRRSNDLLQECIQNyrkipeLPDCPAelkkiaLVRMA 215
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGL------DPDDPA------ALSLL 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1806705737 216 GR-LSFLGRMRQAAAALEKVASLFPSDVKVLKDLGVQYLMYGNNQDAEKVFKKVLKLNPGSGFAKSHLGF---------- 284
Cdd:TIGR02917 370 GEaYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILsylrsgqfdk 449

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1806705737 285 ALKVQLHYQEAIPfliegvtsgdpgaDDGRFYFHLGDALTRTGKPEEANKWYADA 339
Cdd:TIGR02917 450 ALAAAKKLEKKQP-------------DNASLHNLLGAIYLGKGDLAKAREAFEKA 491
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 282-343 6.80e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 35.39  E-value: 6.80e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1806705737 282 LGFALKVQLHYQEAIPFLIEGVTSGDPGADDGRFYFHLGDALTRTGKPEEANKWYADAARKG 343
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAALARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAA 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH