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Conserved domains on  [gi|1785375376|ref|XP_031760087|]
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oocyte zinc finger protein XlCOF6-like isoform X2 [Xenopus tropicalis]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11473154)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940|11179890|12665246|10940247
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
78-462 4.43e-13

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 72.04  E-value: 4.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376  78 KLYSCTECGKRFSLFPSLVTHIRIHAGEKPFTCIECGKTFNRKD------HLRMHQKLHRE--------QKQFTC----A 139
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplelsrHLRTHHNNPSDlnskslplSNSKASssslS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 140 ICAERFVSERKLQTHQAIHMEKNLFTCTECGKSFSKKSSLRVHHRIHTGEK-------PFTCRECGKSFSSTHSLRMHER 212
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 213 IHTGEKPFTCAKCGRSFVEKGRL-TRHEMTHKNKPYVCSECDRKFPDMEKLRLHQAVHIQNKCSNCKVCGKCFSHERFLK 291
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSsSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 292 KHERIHTAE-------KPFSCTECWKTFTEKSRLLIHQR--IHTGE--KPFFCTE--CGKSFIEKRILQIHQRCHTGEKP 358
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 359 FTC-------TKCGKGFNEKRTLRVHEIIHTRKRPFIC--KECGKSFSAKSTFHVHKRFHTRKKP--FTCPECGKSFTAK 427
Cdd:COG5048   352 AKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 1785375376 428 RTLLIHERTHTGEKPFACIECGKCFTAKTGLNRHQ 462
Cdd:COG5048   432 YNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
598-622 2.43e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.43e-04
                          10        20
                  ....*....|....*....|....*
gi 1785375376 598 LRRHERTHTGEKPYTCTECGKSFTT 622
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
570-593 3.64e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 3.64e-04
                          10        20
                  ....*....|....*....|....
gi 1785375376 570 LRRHERTHTGEKPFKCSKCGKSFT 593
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 495-578 2.03e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 495 EEKPFTCRGDGKNVT-ENSSLCKHERIHTEEKPFTcrgdgknvTENSSLCKHERIHTGEKPFTCSECGKRYTEKFQLRRH 573
Cdd:COG5189   346 DGKPYKCPVEGCNKKyKNQNGLKYHMLHGHQNQKL--------HENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH 417


                  ....*
gi 1785375376 574 eRTHT 578
Cdd:COG5189   418 -RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
458-482 5.10e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.10e-03
                          10        20
                  ....*....|....*....|....*
gi 1785375376 458 LNRHQKVHTGEKPFTCKKCGKCFTR 482
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
78-462 4.43e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 72.04  E-value: 4.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376  78 KLYSCTECGKRFSLFPSLVTHIRIHAGEKPFTCIECGKTFNRKD------HLRMHQKLHRE--------QKQFTC----A 139
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplelsrHLRTHHNNPSDlnskslplSNSKASssslS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 140 ICAERFVSERKLQTHQAIHMEKNLFTCTECGKSFSKKSSLRVHHRIHTGEK-------PFTCRECGKSFSSTHSLRMHER 212
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 213 IHTGEKPFTCAKCGRSFVEKGRL-TRHEMTHKNKPYVCSECDRKFPDMEKLRLHQAVHIQNKCSNCKVCGKCFSHERFLK 291
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSsSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 292 KHERIHTAE-------KPFSCTECWKTFTEKSRLLIHQR--IHTGE--KPFFCTE--CGKSFIEKRILQIHQRCHTGEKP 358
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 359 FTC-------TKCGKGFNEKRTLRVHEIIHTRKRPFIC--KECGKSFSAKSTFHVHKRFHTRKKP--FTCPECGKSFTAK 427
Cdd:COG5048   352 AKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 1785375376 428 RTLLIHERTHTGEKPFACIECGKCFTAKTGLNRHQ 462
Cdd:COG5048   432 YNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
598-622 2.43e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.43e-04
                          10        20
                  ....*....|....*....|....*
gi 1785375376 598 LRRHERTHTGEKPYTCTECGKSFTT 622
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
570-593 3.64e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 3.64e-04
                          10        20
                  ....*....|....*....|....
gi 1785375376 570 LRRHERTHTGEKPFKCSKCGKSFT 593
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 495-578 2.03e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 495 EEKPFTCRGDGKNVT-ENSSLCKHERIHTEEKPFTcrgdgknvTENSSLCKHERIHTGEKPFTCSECGKRYTEKFQLRRH 573
Cdd:COG5189   346 DGKPYKCPVEGCNKKyKNQNGLKYHMLHGHQNQKL--------HENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH 417


                  ....*
gi 1785375376 574 eRTHT 578
Cdd:COG5189   418 -RKHS 421
transpos_ISL3 NF033550
ISL3 family transposase;
351-411 3.05e-03

ISL3 family transposase;


Pssm-ID: 468079 [Multi-domain]  Cd Length: 369  Bit Score: 40.26  E-value: 3.05e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1785375376 351 RCHTGEKPFTCTKCGKG-----FNEKRTLRvHE-------IIHTRKRPFICKECGKSFSAKSTFHVHKRFHTR 411
Cdd:NF033550    3 EAELTRGDATCPECGKPsrrvhDTGKRRIR-HLpifgrpvYLELRVRRFKCPECGKTFTEELPWARKRSRITL 74
zf-H2C2_2 pfam13465
Zinc-finger double domain;
178-203 3.28e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.28e-03
                          10        20
                  ....*....|....*....|....*.
gi 1785375376 178 SLRVHHRIHTGEKPFTCRECGKSFSS 203
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
458-482 5.10e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.10e-03
                          10        20
                  ....*....|....*....|....*
gi 1785375376 458 LNRHQKVHTGEKPFTCKKCGKCFTR 482
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 332-377 9.89e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 35.61  E-value: 9.89e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1785375376 332 FCTECGKSFIEKRILQIHQRchtgEKPFTCTKCGKGFNEKRTLRVH 377
Cdd:cd20908     3 WCYYCDREFDDEKILIQHQK----AKHFKCHICHKKLYTAGGLAVH 44
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
78-462 4.43e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 72.04  E-value: 4.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376  78 KLYSCTECGKRFSLFPSLVTHIRIHAGEKPFTCIECGKTFNRKD------HLRMHQKLHRE--------QKQFTC----A 139
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplelsrHLRTHHNNPSDlnskslplSNSKASssslS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 140 ICAERFVSERKLQTHQAIHMEKNLFTCTECGKSFSKKSSLRVHHRIHTGEK-------PFTCRECGKSFSSTHSLRMHER 212
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 213 IHTGEKPFTCAKCGRSFVEKGRL-TRHEMTHKNKPYVCSECDRKFPDMEKLRLHQAVHIQNKCSNCKVCGKCFSHERFLK 291
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSsSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 292 KHERIHTAE-------KPFSCTECWKTFTEKSRLLIHQR--IHTGE--KPFFCTE--CGKSFIEKRILQIHQRCHTGEKP 358
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 359 FTC-------TKCGKGFNEKRTLRVHEIIHTRKRPFIC--KECGKSFSAKSTFHVHKRFHTRKKP--FTCPECGKSFTAK 427
Cdd:COG5048   352 AKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 1785375376 428 RTLLIHERTHTGEKPFACIECGKCFTAKTGLNRHQ 462
Cdd:COG5048   432 YNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
147-592 4.63e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.49  E-value: 4.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 147 SERKLQTHQAIHMEKNLFTCTECGKSFSKKSSLRVHHRIHTGEKPFTCR--ECGKSFSSTHSLRMHERIHTGEKPFTCAK 224
Cdd:COG5048    17 SSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSK 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 225 CGRSFVEKGRLTRHEMTHKNKPYVCSECDRKFPDMEKLRLHQAVHiqnkcSNCKVcGKCFSHERFLKKHERIHTAEKPFS 304
Cdd:COG5048    97 SLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLL-----SISNL-RNNPLPGNNSSSVNTPQSNSLHPP 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 305 CT--ECWKTFTEKSRLLIHQRIHTGEKPFFCTECGKSFIEKRILQIHQRCHTGEKPFTCTKCGKGFNEKRTLrvheiiht 382
Cdd:COG5048   171 LPanSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLS-------- 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 383 rkrpfickeCGKSFSAKSTFHVHKrfhtrKKPFTCPECGKSFTAKRTLLIHERTHTG-EKPFACIECGKCFTAKTGLNRH 461
Cdd:COG5048   243 ---------QSPSSLSSSDSSSSA-----SESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRH 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 462 Q--KVHTGE--KPFTCKK--CGKCFTRKENLKMHQNIHTEEKPFTC--RGDGKNVTENSSLCKHERIH-----TEEKPFT 528
Cdd:COG5048   309 LrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSE 388

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1785375376 529 CRGDG--KNVTENSSLCKHERIHTGEKP--FTCSECGKRYTEKFQLRRHERTHTGEKPFKCSKCGKSF 592
Cdd:COG5048   389 TLSNSciRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFR 456
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
257-677 5.19e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.49  E-value: 5.19e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 257 PDMEKLRLHQAVHIQNKCSNCKVCGKCFSHERFLKKHERIHTAEKPFSCT--ECWKTFTEKSRLLIHQRIHTGEKPffct 334
Cdd:COG5048    16 LSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPS---- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 335 ecgksfiekrILQIHQRCHTGEKPFTC--TKCGKGFNEKRTLRVHEIIHTRKRPFICKECGKSFSAKSTFHVHKRFHTRK 412
Cdd:COG5048    92 ----------DLNSKSLPLSNSKASSSslSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNT 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 413 K-------PFTCPECGKSFTAKRTLLIHERTHTGEKPFACIECGKCFTAKTGLNRHQKVHTGEKPFTCKKCGKCFTRKEN 485
Cdd:COG5048   162 PqsnslhpPLPANSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 486 LKMHQNIHTEEKPFTCRGDGKNVTENSSLCKHERIHTEE-------KPFTCRGDGKNVTENSSLCKHER--IHTGE--KP 554
Cdd:COG5048   242 SQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKP 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 555 FTCSE--CGKRYTEKFQLRRHERTHTGEKPFKC--SKCGKSFT-----EKFQLRRHERTHTGEKPYTCT--ECGKSFTTK 623
Cdd:COG5048   322 FSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRD 401

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1785375376 624 SILKRHHSAHNGEKP--FTCTECGKGFVSLYNLDVHKATHTgrNHSPVQNDEKGSF 677
Cdd:COG5048   402 SNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT--NHAPLLCSILKSF 455
zf-H2C2_2 pfam13465
Zinc-finger double domain;
598-622 2.43e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.43e-04
                          10        20
                  ....*....|....*....|....*
gi 1785375376 598 LRRHERTHTGEKPYTCTECGKSFTT 622
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
570-593 3.64e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 3.64e-04
                          10        20
                  ....*....|....*....|....
gi 1785375376 570 LRRHERTHTGEKPFKCSKCGKSFT 593
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 551-633 1.48e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 1.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 551 GEKPFTCS--ECGKRYTEKFQLRRHeRTHtgekpfkcSKCGKSFTEKFQLRRHERTHTGEKPYTCTECGKSFTTKSILKR 628
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*..
gi 1785375376 629 H--HSAH 633
Cdd:COG5189   417 HrkHSHD 423
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 495-578 2.03e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375376 495 EEKPFTCRGDGKNVT-ENSSLCKHERIHTEEKPFTcrgdgknvTENSSLCKHERIHTGEKPFTCSECGKRYTEKFQLRRH 573
Cdd:COG5189   346 DGKPYKCPVEGCNKKyKNQNGLKYHMLHGHQNQKL--------HENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH 417


                  ....*
gi 1785375376 574 eRTHT 578
Cdd:COG5189   418 -RKHS 421
transpos_ISL3 NF033550
ISL3 family transposase;
351-411 3.05e-03

ISL3 family transposase;


Pssm-ID: 468079 [Multi-domain]  Cd Length: 369  Bit Score: 40.26  E-value: 3.05e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1785375376 351 RCHTGEKPFTCTKCGKG-----FNEKRTLRvHE-------IIHTRKRPFICKECGKSFSAKSTFHVHKRFHTR 411
Cdd:NF033550    3 EAELTRGDATCPECGKPsrrvhDTGKRRIR-HLpifgrpvYLELRVRRFKCPECGKTFTEELPWARKRSRITL 74
zf-H2C2_2 pfam13465
Zinc-finger double domain;
178-203 3.28e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.28e-03
                          10        20
                  ....*....|....*....|....*.
gi 1785375376 178 SLRVHHRIHTGEKPFTCRECGKSFSS 203
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
458-482 5.10e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.10e-03
                          10        20
                  ....*....|....*....|....*
gi 1785375376 458 LNRHQKVHTGEKPFTCKKCGKCFTR 482
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
206-230 8.85e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 8.85e-03
                          10        20
                  ....*....|....*....|....*
gi 1785375376 206 SLRMHERIHTGEKPFTCAKCGRSFV 230
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 332-377 9.89e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 35.61  E-value: 9.89e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1785375376 332 FCTECGKSFIEKRILQIHQRchtgEKPFTCTKCGKGFNEKRTLRVH 377
Cdd:cd20908     3 WCYYCDREFDDEKILIQHQK----AKHFKCHICHKKLYTAGGLAVH 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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