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Conserved domains on  [gi|1785375374|ref|XP_031760086|]
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oocyte zinc finger protein XlCOF6-like isoform X1 [Xenopus tropicalis]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11473154)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940|11179890|12665246|10940247
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
82-466 6.42e-13

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 71.27  E-value: 6.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374  82 KLYSCTECGKRFSLFPSLVTHIRIHAGEKPFTCIECGKTFNRKD------HLRMHQKLHRE--------QKQFTC----A 143
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplelsrHLRTHHNNPSDlnskslplSNSKASssslS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 144 ICAERFVSERKLQTHQAIHMEKNLFTCTECGKSFSKKSSLRVHHRIHTGEK-------PFTCRECGKSFSSTHSLRMHER 216
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 217 IHTGEKPFTCAKCGRSFVEKGRL-TRHEMTHKNKPYVCSECDRKFPDMEKLRLHQAVHIQNKCSNCKVCGKCFSHERFLK 295
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSsSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 296 KHERIHTAE-------KPFSCTECWKTFTEKSRLLIHQR--IHTGE--KPFFCTE--CGKSFIEKRILQIHQRCHTGEKP 362
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 363 FTC-------TKCGKGFNEKRTLRVHEIIHTRKRPFIC--KECGKSFSAKSTFHVHKRFHTRKKP--FTCPECGKSFTAK 431
Cdd:COG5048   352 AKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 1785375374 432 RTLLIHERTHTGEKPFACIECGKCFTAKTGLNRHQ 466
Cdd:COG5048   432 YNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
602-626 2.37e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.37e-04
                          10        20
                  ....*....|....*....|....*
gi 1785375374 602 LRRHERTHTGEKPYTCTECGKSFTT 626
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
574-597 3.55e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 3.55e-04
                          10        20
                  ....*....|....*....|....
gi 1785375374 574 LRRHERTHTGEKPFKCSKCGKSFT 597
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 499-582 2.11e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 499 EEKPFTCRGDGKNVT-ENSSLCKHERIHTEEKPFTcrgdgknvTENSSLCKHERIHTGEKPFTCSECGKRYTEKFQLRRH 577
Cdd:COG5189   346 DGKPYKCPVEGCNKKyKNQNGLKYHMLHGHQNQKL--------HENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH 417


                  ....*
gi 1785375374 578 eRTHT 582
Cdd:COG5189   418 -RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
462-486 5.03e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.03e-03
                          10        20
                  ....*....|....*....|....*
gi 1785375374 462 LNRHQKVHTGEKPFTCKKCGKCFTR 486
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
82-466 6.42e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 71.27  E-value: 6.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374  82 KLYSCTECGKRFSLFPSLVTHIRIHAGEKPFTCIECGKTFNRKD------HLRMHQKLHRE--------QKQFTC----A 143
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplelsrHLRTHHNNPSDlnskslplSNSKASssslS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 144 ICAERFVSERKLQTHQAIHMEKNLFTCTECGKSFSKKSSLRVHHRIHTGEK-------PFTCRECGKSFSSTHSLRMHER 216
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 217 IHTGEKPFTCAKCGRSFVEKGRL-TRHEMTHKNKPYVCSECDRKFPDMEKLRLHQAVHIQNKCSNCKVCGKCFSHERFLK 295
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSsSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 296 KHERIHTAE-------KPFSCTECWKTFTEKSRLLIHQR--IHTGE--KPFFCTE--CGKSFIEKRILQIHQRCHTGEKP 362
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 363 FTC-------TKCGKGFNEKRTLRVHEIIHTRKRPFIC--KECGKSFSAKSTFHVHKRFHTRKKP--FTCPECGKSFTAK 431
Cdd:COG5048   352 AKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 1785375374 432 RTLLIHERTHTGEKPFACIECGKCFTAKTGLNRHQ 466
Cdd:COG5048   432 YNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
602-626 2.37e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.37e-04
                          10        20
                  ....*....|....*....|....*
gi 1785375374 602 LRRHERTHTGEKPYTCTECGKSFTT 626
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
574-597 3.55e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 3.55e-04
                          10        20
                  ....*....|....*....|....
gi 1785375374 574 LRRHERTHTGEKPFKCSKCGKSFT 597
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 499-582 2.11e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 499 EEKPFTCRGDGKNVT-ENSSLCKHERIHTEEKPFTcrgdgknvTENSSLCKHERIHTGEKPFTCSECGKRYTEKFQLRRH 577
Cdd:COG5189   346 DGKPYKCPVEGCNKKyKNQNGLKYHMLHGHQNQKL--------HENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH 417


                  ....*
gi 1785375374 578 eRTHT 582
Cdd:COG5189   418 -RKHS 421
transpos_ISL3 NF033550
ISL3 family transposase;
355-415 2.97e-03

ISL3 family transposase;


Pssm-ID: 468079 [Multi-domain]  Cd Length: 369  Bit Score: 40.26  E-value: 2.97e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1785375374 355 RCHTGEKPFTCTKCGKG-----FNEKRTLRvHE-------IIHTRKRPFICKECGKSFSAKSTFHVHKRFHTR 415
Cdd:NF033550    3 EAELTRGDATCPECGKPsrrvhDTGKRRIR-HLpifgrpvYLELRVRRFKCPECGKTFTEELPWARKRSRITL 74
zf-H2C2_2 pfam13465
Zinc-finger double domain;
182-207 3.20e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.20e-03
                          10        20
                  ....*....|....*....|....*.
gi 1785375374 182 SLRVHHRIHTGEKPFTCRECGKSFSS 207
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
462-486 5.03e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.03e-03
                          10        20
                  ....*....|....*....|....*
gi 1785375374 462 LNRHQKVHTGEKPFTCKKCGKCFTR 486
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 336-381 9.20e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 35.61  E-value: 9.20e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1785375374 336 FCTECGKSFIEKRILQIHQRchtgEKPFTCTKCGKGFNEKRTLRVH 381
Cdd:cd20908     3 WCYYCDREFDDEKILIQHQK----AKHFKCHICHKKLYTAGGLAVH 44
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
82-466 6.42e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 71.27  E-value: 6.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374  82 KLYSCTECGKRFSLFPSLVTHIRIHAGEKPFTCIECGKTFNRKD------HLRMHQKLHRE--------QKQFTC----A 143
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplelsrHLRTHHNNPSDlnskslplSNSKASssslS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 144 ICAERFVSERKLQTHQAIHMEKNLFTCTECGKSFSKKSSLRVHHRIHTGEK-------PFTCRECGKSFSSTHSLRMHER 216
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 217 IHTGEKPFTCAKCGRSFVEKGRL-TRHEMTHKNKPYVCSECDRKFPDMEKLRLHQAVHIQNKCSNCKVCGKCFSHERFLK 295
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSsSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 296 KHERIHTAE-------KPFSCTECWKTFTEKSRLLIHQR--IHTGE--KPFFCTE--CGKSFIEKRILQIHQRCHTGEKP 362
Cdd:COG5048   272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 363 FTC-------TKCGKGFNEKRTLRVHEIIHTRKRPFIC--KECGKSFSAKSTFHVHKRFHTRKKP--FTCPECGKSFTAK 431
Cdd:COG5048   352 AKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 1785375374 432 RTLLIHERTHTGEKPFACIECGKCFTAKTGLNRHQ 466
Cdd:COG5048   432 YNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
151-596 6.24e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.10  E-value: 6.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 151 SERKLQTHQAIHMEKNLFTCTECGKSFSKKSSLRVHHRIHTGEKPFTCR--ECGKSFSSTHSLRMHERIHTGEKPFTCAK 228
Cdd:COG5048    17 SSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSK 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 229 CGRSFVEKGRLTRHEMTHKNKPYVCSECDRKFPDMEKLRLHQAVHiqnkcSNCKVcGKCFSHERFLKKHERIHTAEKPFS 308
Cdd:COG5048    97 SLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLL-----SISNL-RNNPLPGNNSSSVNTPQSNSLHPP 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 309 CT--ECWKTFTEKSRLLIHQRIHTGEKPFFCTECGKSFIEKRILQIHQRCHTGEKPFTCTKCGKGFNEKRTLrvheiiht 386
Cdd:COG5048   171 LPanSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLS-------- 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 387 rkrpfickeCGKSFSAKSTFHVHKrfhtrKKPFTCPECGKSFTAKRTLLIHERTHTG-EKPFACIECGKCFTAKTGLNRH 465
Cdd:COG5048   243 ---------QSPSSLSSSDSSSSA-----SESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRH 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 466 Q--KVHTGE--KPFTCKK--CGKCFTRKENLKMHQNIHTEEKPFTC--RGDGKNVTENSSLCKHERIH-----TEEKPFT 532
Cdd:COG5048   309 LrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSE 388

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1785375374 533 C--RGDGKNVTENSSLCKHERIHTGEKP--FTCSECGKRYTEKFQLRRHERTHTGEKPFKCSKCGKSF 596
Cdd:COG5048   389 TlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFR 456
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
261-681 6.87e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.10  E-value: 6.87e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 261 PDMEKLRLHQAVHIQNKCSNCKVCGKCFSHERFLKKHERIHTAEKPFSCT--ECWKTFTEKSRLLIHQRIHTGEKPffct 338
Cdd:COG5048    16 LSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPS---- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 339 ecgksfiekrILQIHQRCHTGEKPFTC--TKCGKGFNEKRTLRVHEIIHTRKRPFICKECGKSFSAKSTFHVHKRFHTRK 416
Cdd:COG5048    92 ----------DLNSKSLPLSNSKASSSslSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNT 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 417 K-------PFTCPECGKSFTAKRTLLIHERTHTGEKPFACIECGKCFTAKTGLNRHQKVHTGEKPFTCKKCGKCFTRKEN 489
Cdd:COG5048   162 PqsnslhpPLPANSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 490 LKMHQNIHTEEKPFTCRGDGKNVTENSSLCKHERIHTEE-------KPFTCRGDGKNVTENSSLCKHER--IHTGE--KP 558
Cdd:COG5048   242 SQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKP 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 559 FTCSE--CGKRYTEKFQLRRHERTHTGEKPFKC--SKCGKSFT-----EKFQLRRHERTHTGEKPYTCT--ECGKSFTTK 627
Cdd:COG5048   322 FSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpllnnEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRD 401

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1785375374 628 SILKRHHSAHNGEKP--FTCTECGKGFVSLYNLDVHKATHTgrNHSPVQNDEKGSF 681
Cdd:COG5048   402 SNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT--NHAPLLCSILKSF 455
zf-H2C2_2 pfam13465
Zinc-finger double domain;
602-626 2.37e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.37e-04
                          10        20
                  ....*....|....*....|....*
gi 1785375374 602 LRRHERTHTGEKPYTCTECGKSFTT 626
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
574-597 3.55e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 3.55e-04
                          10        20
                  ....*....|....*....|....
gi 1785375374 574 LRRHERTHTGEKPFKCSKCGKSFT 597
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 555-637 1.55e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 555 GEKPFTCS--ECGKRYTEKFQLRRHeRTHtgekpfkcSKCGKSFTEKFQLRRHERTHTGEKPYTCTECGKSFTTKSILKR 632
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*..
gi 1785375374 633 H--HSAH 637
Cdd:COG5189   417 HrkHSHD 423
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 499-582 2.11e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785375374 499 EEKPFTCRGDGKNVT-ENSSLCKHERIHTEEKPFTcrgdgknvTENSSLCKHERIHTGEKPFTCSECGKRYTEKFQLRRH 577
Cdd:COG5189   346 DGKPYKCPVEGCNKKyKNQNGLKYHMLHGHQNQKL--------HENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH 417


                  ....*
gi 1785375374 578 eRTHT 582
Cdd:COG5189   418 -RKHS 421
transpos_ISL3 NF033550
ISL3 family transposase;
355-415 2.97e-03

ISL3 family transposase;


Pssm-ID: 468079 [Multi-domain]  Cd Length: 369  Bit Score: 40.26  E-value: 2.97e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1785375374 355 RCHTGEKPFTCTKCGKG-----FNEKRTLRvHE-------IIHTRKRPFICKECGKSFSAKSTFHVHKRFHTR 415
Cdd:NF033550    3 EAELTRGDATCPECGKPsrrvhDTGKRRIR-HLpifgrpvYLELRVRRFKCPECGKTFTEELPWARKRSRITL 74
zf-H2C2_2 pfam13465
Zinc-finger double domain;
182-207 3.20e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.20e-03
                          10        20
                  ....*....|....*....|....*.
gi 1785375374 182 SLRVHHRIHTGEKPFTCRECGKSFSS 207
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
462-486 5.03e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.03e-03
                          10        20
                  ....*....|....*....|....*
gi 1785375374 462 LNRHQKVHTGEKPFTCKKCGKCFTR 486
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
210-234 8.72e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 8.72e-03
                          10        20
                  ....*....|....*....|....*
gi 1785375374 210 SLRMHERIHTGEKPFTCAKCGRSFV 234
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 336-381 9.20e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 35.61  E-value: 9.20e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1785375374 336 FCTECGKSFIEKRILQIHQRchtgEKPFTCTKCGKGFNEKRTLRVH 381
Cdd:cd20908     3 WCYYCDREFDDEKILIQHQK----AKHFKCHICHKKLYTAGGLAVH 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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