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Conserved domains on  [gi|1756860160|ref|XP_030918913|]
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succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial [Geospiza fortis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00187 super family cl36524
succinyl-CoA synthetase alpha subunit; Provisional
 12-264 7.07e-151

succinyl-CoA synthetase alpha subunit; Provisional


The actual alignment was detected with superfamily member PTZ00187:

Pssm-ID: 240307 [Multi-domain]  Cd Length: 317  Bit Score: 423.74  E-value: 7.07e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  12 GKTHL--GLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKHRLLRQNKTRLVG 89
Cdd:PTZ00187   66 GTTHLkhGLPVFATVKEAKKATGADASVIYVPPPHAASAIIEAIEAEIPLVVCITEGIPQHDMVKVKHALLSQNKTRLIG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  90 PNCPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKDPHT 169
Cdd:PTZ00187  146 PNCPGIIKPGECKIGIMPGHIHKKGKIGIVSRSGTLTYEAVAQTTAVGLGQSTCVGIGGDPFNGTNFIDCLKLFLNDPET 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 170 EGIILIGEIGGNAEEDAAAFLKENnsgPNAKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVSMSP 249
Cdd:PTZ00187  226 EGIILIGEIGGTAEEEAAEWIKNN---PIKKPVVSFIAGITAPPGRRMGHAGAIISGGKGTAPGKIEALEAAGVRVVKSP 302

                         250
                  ....*....|....*
gi 1756860160 250 AQLGSTIYKEFEKRK 264
Cdd:PTZ00187  303 AQLGKTMLEVMKKKG 317
 
Name Accession Description Interval E-value
PTZ00187 PTZ00187
succinyl-CoA synthetase alpha subunit; Provisional
 12-264 7.07e-151

succinyl-CoA synthetase alpha subunit; Provisional


Pssm-ID: 240307 [Multi-domain]  Cd Length: 317  Bit Score: 423.74  E-value: 7.07e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  12 GKTHL--GLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKHRLLRQNKTRLVG 89
Cdd:PTZ00187   66 GTTHLkhGLPVFATVKEAKKATGADASVIYVPPPHAASAIIEAIEAEIPLVVCITEGIPQHDMVKVKHALLSQNKTRLIG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  90 PNCPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKDPHT 169
Cdd:PTZ00187  146 PNCPGIIKPGECKIGIMPGHIHKKGKIGIVSRSGTLTYEAVAQTTAVGLGQSTCVGIGGDPFNGTNFIDCLKLFLNDPET 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 170 EGIILIGEIGGNAEEDAAAFLKENnsgPNAKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVSMSP 249
Cdd:PTZ00187  226 EGIILIGEIGGTAEEEAAEWIKNN---PIKKPVVSFIAGITAPPGRRMGHAGAIISGGKGTAPGKIEALEAAGVRVVKSP 302

                         250
                  ....*....|....*
gi 1756860160 250 AQLGSTIYKEFEKRK 264
Cdd:PTZ00187  303 AQLGKTMLEVMKKKG 317
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 10-258 1.13e-131

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 373.63  E-value: 1.13e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  10 HPGK---THLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKhRLLRQNKTR 86
Cdd:COG0074    39 TPGKggqTVLGVPVFDTVAEAVEETGADASVIFVPPPFAADAILEAIDAGIKLIVCITEGIPVLDMVRVK-RYAKAKGTR 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  87 LVGPNCPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKD 166
Cdd:COG0074   118 LIGPNCPGIITPGECKLGIMPGHIFKPGRVGIVSRSGTLTYEAVWQLTQAGLGQSTCVGIGGDPIIGTSFIDVLELFEED 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 167 PHTEGIILIGEIGGNAEEDAAAFLKENNSgpnaKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVS 246
Cdd:COG0074   198 PETEAIVMIGEIGGSAEEEAAEYIKENMT----KPVVAYIAGRTAPPGKRMGHAGAIISGGKGTAESKIEALEAAGVPVA 273

                         250
                  ....*....|..
gi 1756860160 247 MSPAQLGSTIYK 258
Cdd:COG0074   274 ESPSEIGELLKK 285
sucCoAalpha TIGR01019
succinyl-CoA synthetase, alpha subunit; This model describes succinyl-CoA synthetase alpha ...
 11-256 3.25e-121

succinyl-CoA synthetase, alpha subunit; This model describes succinyl-CoA synthetase alpha subunits but does not discriminate between GTP-specific and ATP-specific reactions. The model is designated as subfamily rather than equivalog for that reason. ATP citrate lyases appear to form an outgroup. [Energy metabolism, TCA cycle]


Pssm-ID: 130091 [Multi-domain]  Cd Length: 286  Bit Score: 347.48  E-value: 3.25e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  11 PGK---THLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKhRLLRQNKTRL 87
Cdd:TIGR01019  39 PGKggtTVLGLPVFDSVKEAVEETGANASVIFVPAPFAADAIFEAIDAGIELIVCITEGIPVHDMLKVK-RYMEESGTRL 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  88 VGPNCPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKDP 167
Cdd:TIGR01019 118 IGPNCPGIITPGECKIGIMPGHIHKPGNVGIVSRSGTLTYEAVHQLTKAGFGQSTCVGIGGDPVNGTSFIDVLEAFEKDP 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 168 HTEGIILIGEIGGNAEEDAAAFLKENNSgpnaKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVSM 247
Cdd:TIGR01019 198 ETEAIVMIGEIGGSAEEEAADFIKQNMS----KPVVGFIAGATAPPGKRMGHAGAIISGGKGTAESKIEALEAAGVTVVK 273


                  ....*....
gi 1756860160 248 SPAQLGSTI 256
Cdd:TIGR01019 274 SPSDIGELL 282
Ligase_CoA pfam00549
CoA-ligase; This family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, ...
 119-244 4.11e-23

CoA-ligase; This family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, malate CoA ligase and ATP-citrate lyase. Some members of the family utilize ATP others use GTP.


Pssm-ID: 395434 [Multi-domain]  Cd Length: 128  Bit Score: 91.17  E-value: 4.11e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 119 VSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKDPHTEGIILIGEIGGNAEED-AAAFLKE-NNSG 196
Cdd:pfam00549   1 LVNGGTLAMEAMDLIKLAGGGPHNFIDLGGDAFTPTTRIDALKLEAADPEVKVILLDIVLGYGACEDpAGGLLKAiKEAR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1756860160 197 PNAKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVV 244
Cdd:pfam00549  81 ARELPVVARVCGTEADPQGRSGQAKALAESGVLIASSNNQALRAAGAV 128
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 12-67 2.62e-16

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 72.16  E-value: 2.62e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1756860160   12 GKTHLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGI 67
Cdd:smart00881  45 GPKVDGVPVYDSVAEAPEETGVDVAVIFVPAEAAPDAIDEAIEAGIKGIVVITEGI 100
 
Name Accession Description Interval E-value
PTZ00187 PTZ00187
succinyl-CoA synthetase alpha subunit; Provisional
 12-264 7.07e-151

succinyl-CoA synthetase alpha subunit; Provisional


Pssm-ID: 240307 [Multi-domain]  Cd Length: 317  Bit Score: 423.74  E-value: 7.07e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  12 GKTHL--GLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKHRLLRQNKTRLVG 89
Cdd:PTZ00187   66 GTTHLkhGLPVFATVKEAKKATGADASVIYVPPPHAASAIIEAIEAEIPLVVCITEGIPQHDMVKVKHALLSQNKTRLIG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  90 PNCPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKDPHT 169
Cdd:PTZ00187  146 PNCPGIIKPGECKIGIMPGHIHKKGKIGIVSRSGTLTYEAVAQTTAVGLGQSTCVGIGGDPFNGTNFIDCLKLFLNDPET 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 170 EGIILIGEIGGNAEEDAAAFLKENnsgPNAKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVSMSP 249
Cdd:PTZ00187  226 EGIILIGEIGGTAEEEAAEWIKNN---PIKKPVVSFIAGITAPPGRRMGHAGAIISGGKGTAPGKIEALEAAGVRVVKSP 302

                         250
                  ....*....|....*
gi 1756860160 250 AQLGSTIYKEFEKRK 264
Cdd:PTZ00187  303 AQLGKTMLEVMKKKG 317
PRK05678 PRK05678
succinyl-CoA synthetase subunit alpha; Validated
 10-256 1.60e-133

succinyl-CoA synthetase subunit alpha; Validated


Pssm-ID: 180194 [Multi-domain]  Cd Length: 291  Bit Score: 378.75  E-value: 1.60e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  10 HPGK---THLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKhRLLRQNKTR 86
Cdd:PRK05678   40 TPGKggtTVLGLPVFNTVAEAVEATGANASVIYVPPPFAADAILEAIDAGIDLIVCITEGIPVLDMLEVK-AYLERKKTR 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  87 LVGPNCPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKD 166
Cdd:PRK05678  119 LIGPNCPGIITPGECKIGIMPGHIHKKGRVGVVSRSGTLTYEAVAQLTDLGFGQSTCVGIGGDPINGTNFIDVLEAFEED 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 167 PHTEGIILIGEIGGNAEEDAAAFLKENNSgpnaKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVS 246
Cdd:PRK05678  199 PETEAIVMIGEIGGSAEEEAAEYIKANVT----KPVVGYIAGVTAPPGKRMGHAGAIISGGKGTAEEKKEALEAAGVKVA 274

                         250
                  ....*....|
gi 1756860160 247 MSPAQLGSTI 256
Cdd:PRK05678  275 RTPSEIGELL 284
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 10-258 1.13e-131

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 373.63  E-value: 1.13e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  10 HPGK---THLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKhRLLRQNKTR 86
Cdd:COG0074    39 TPGKggqTVLGVPVFDTVAEAVEETGADASVIFVPPPFAADAILEAIDAGIKLIVCITEGIPVLDMVRVK-RYAKAKGTR 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  87 LVGPNCPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKD 166
Cdd:COG0074   118 LIGPNCPGIITPGECKLGIMPGHIFKPGRVGIVSRSGTLTYEAVWQLTQAGLGQSTCVGIGGDPIIGTSFIDVLELFEED 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 167 PHTEGIILIGEIGGNAEEDAAAFLKENNSgpnaKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVS 246
Cdd:COG0074   198 PETEAIVMIGEIGGSAEEEAAEYIKENMT----KPVVAYIAGRTAPPGKRMGHAGAIISGGKGTAESKIEALEAAGVPVA 273

                         250
                  ....*....|..
gi 1756860160 247 MSPAQLGSTIYK 258
Cdd:COG0074   274 ESPSEIGELLKK 285
PLN00125 PLN00125
Succinyl-CoA ligase [GDP-forming] subunit alpha
 12-266 5.38e-130

Succinyl-CoA ligase [GDP-forming] subunit alpha


Pssm-ID: 215066 [Multi-domain]  Cd Length: 300  Bit Score: 370.07  E-value: 5.38e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  12 GKTHLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKHRLLRQNKTRLVGPN 91
Cdd:PLN00125   49 GTEHLGLPVFNTVAEAKAETKANASVIYVPPPFAAAAILEAMEAELDLVVCITEGIPQHDMVRVKAALNRQSKTRLIGPN 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  92 CPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKDPHTEG 171
Cdd:PLN00125  129 CPGIIKPGECKIGIMPGYIHKPGRIGIVSRSGTLTYEAVFQTTAVGLGQSTCVGIGGDPFNGTNFVDCLEKFVKDPQTEG 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 172 IILIGEIGGNAEEDAAAFLKENNSgpnAKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVSMSPAQ 251
Cdd:PLN00125  209 IILIGEIGGTAEEDAAAFIKESGT---EKPVVAFIAGLTAPPGRRMGHAGAIVSGGKGTAQDKIKALREAGVTVVESPAK 285

                         250
                  ....*....|....*
gi 1756860160 252 LGSTIYKEFEKRKLL 266
Cdd:PLN00125  286 IGVAMLEVFKERGLL 300
sucCoAalpha TIGR01019
succinyl-CoA synthetase, alpha subunit; This model describes succinyl-CoA synthetase alpha ...
 11-256 3.25e-121

succinyl-CoA synthetase, alpha subunit; This model describes succinyl-CoA synthetase alpha subunits but does not discriminate between GTP-specific and ATP-specific reactions. The model is designated as subfamily rather than equivalog for that reason. ATP citrate lyases appear to form an outgroup. [Energy metabolism, TCA cycle]


Pssm-ID: 130091 [Multi-domain]  Cd Length: 286  Bit Score: 347.48  E-value: 3.25e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  11 PGK---THLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGIPQQDMVRVKhRLLRQNKTRL 87
Cdd:TIGR01019  39 PGKggtTVLGLPVFDSVKEAVEETGANASVIFVPAPFAADAIFEAIDAGIELIVCITEGIPVHDMLKVK-RYMEESGTRL 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  88 VGPNCPGVINHGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKDP 167
Cdd:TIGR01019 118 IGPNCPGIITPGECKIGIMPGHIHKPGNVGIVSRSGTLTYEAVHQLTKAGFGQSTCVGIGGDPVNGTSFIDVLEAFEKDP 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 168 HTEGIILIGEIGGNAEEDAAAFLKENNSgpnaKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVVVSM 247
Cdd:TIGR01019 198 ETEAIVMIGEIGGSAEEEAADFIKQNMS----KPVVGFIAGATAPPGKRMGHAGAIISGGKGTAESKIEALEAAGVTVVK 273


                  ....*....
gi 1756860160 248 SPAQLGSTI 256
Cdd:TIGR01019 274 SPSDIGELL 282
Ligase_CoA pfam00549
CoA-ligase; This family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, ...
 119-244 4.11e-23

CoA-ligase; This family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, malate CoA ligase and ATP-citrate lyase. Some members of the family utilize ATP others use GTP.


Pssm-ID: 395434 [Multi-domain]  Cd Length: 128  Bit Score: 91.17  E-value: 4.11e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 119 VSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLDVFLKDPHTEGIILIGEIGGNAEED-AAAFLKE-NNSG 196
Cdd:pfam00549   1 LVNGGTLAMEAMDLIKLAGGGPHNFIDLGGDAFTPTTRIDALKLEAADPEVKVILLDIVLGYGACEDpAGGLLKAiKEAR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1756860160 197 PNAKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKIAALQSAGVV 244
Cdd:pfam00549  81 ARELPVVARVCGTEADPQGRSGQAKALAESGVLIASSNNQALRAAGAV 128
CoA_binding pfam02629
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 12-66 8.15e-20

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 396961 [Multi-domain]  Cd Length: 97  Bit Score: 81.48  E-value: 8.15e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1756860160  12 GKTHLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEG 66
Cdd:pfam02629  43 GTEILGIPVYNSVDELEEKTGVDVAVITVPAPFAQEAIDELVDAGIKGIVNITPG 97
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 12-67 2.62e-16

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 72.16  E-value: 2.62e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1756860160   12 GKTHLGLPVFNSVKEAKEQTGASATVIYVPPPFAAAAINEAIDAEMPLVVCITEGI 67
Cdd:smart00881  45 GPKVDGVPVYDSVAEAPEETGVDVAVIFVPAEAAPDAIDEAIEAGIKGIVVITEGI 100
PLN02522 PLN02522
ATP citrate (pro-S)-lyase
 12-262 6.77e-15

ATP citrate (pro-S)-lyase


Pssm-ID: 178137 [Multi-domain]  Cd Length: 608  Bit Score: 74.09  E-value: 6.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  12 GKTHLGLPVFNSVKEA-KEQTGASATVIYVPPPFAAAAINEAIDAE-MPLVVCITEGIPQQDMVRVkHRLLRQNKTRLVG 89
Cdd:PLN02522   57 GQEEIAIPVHGSIEAAcKAHPTADVFINFASFRSAAASSMEALKQPtIRVVAIIAEGVPESDTKQL-IAYARANNKVVIG 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  90 PNCPGVINHGECKIG--------IMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFNGTNFIDCLD 161
Cdd:PLN02522  136 PATVGGIQAGAFKIGdtagtldnIIQCKLYRPGSVGFVSKSGGMSNEMYNVIARVTDGIYEGIAIGGDVFPGSTLSDHVL 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160 162 VFLKDPHTEGIILIGEIGGNAEEDAAAFLKennSGPNAKPVVSFIAGLTA---PPGRRMGHAGAIIAGGKGGAKEKIAAL 238
Cdd:PLN02522  216 RFNNIPQIKMIVVLGELGGRDEYSLVEALK---QGKVSKPVVAWVSGTCArlfKSEVQFGHAGAKSGGDMESAQAKNKAL 292

                         250       260
                  ....*....|....*....|....
gi 1756860160 239 QSAGVVVSMSPAQLGSTIYKEFEK 262
Cdd:PLN02522  293 KDAGAIVPTSFEALEAAIKETFEK 316
PRK06091 PRK06091
membrane protein FdrA; Validated
 33-169 5.42e-06

membrane protein FdrA; Validated


Pssm-ID: 180395 [Multi-domain]  Cd Length: 555  Bit Score: 47.35  E-value: 5.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  33 ASATVIYVPPPFAAAAINEAIDAEMPlVVCITEGIPQQDMVRVKHRLlRQNKTRLVGPNCpgvinhGECKIGIMP---GH 109
Cdd:PRK06091  118 ANLALISVAGEYAAELAEQALDRNLN-VMMFSDNVTLEDEIRLKTRA-REKGLLVMGPDC------GTAMIAGTPlafAN 189

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1756860160 110 IHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGGDPFN----GTNFIDCLDVFLKDPHT 169
Cdd:PRK06091  190 VMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSaevgGISALTALEMLSADEKS 253
Succ_CoA_lig pfam13607
Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from ...
 113-169 2.92e-05

Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from Succinyl-CoA ligase alpha subunit and other related enzymes. A conserved histidine is involved in phosphoryl transfer.


Pssm-ID: 433345 [Multi-domain]  Cd Length: 138  Bit Score: 42.84  E-value: 2.92e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1756860160 113 KGRIGIVSRSGTLTYEAVHQTTQVGLGQSFCVGIGgdpfNGT--NFIDCLDVFLKDPHT 169
Cdd:pfam13607   1 PGNIALVSQSGALGAALLDWARSRGIGFSKFVSLG----NEAdvDFADLLEYLADDPET 55
CoA_binding_2 pfam13380
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 10-97 4.21e-04

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 433162 [Multi-domain]  Cd Length: 116  Bit Score: 39.06  E-value: 4.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1756860160  10 HPGKTH-LGLPVFNSVKEAKEQTGASatVIYVPPPFAAAAINEAIDAEMPLVVCITeGIPQQDMVRvkhrLLRQNKTRLV 88
Cdd:pfam13380  34 NPKAKEiLGEPVYPSLADPPEPVDLV--DVFRPPEAVPEIVEEALALGAKAVWLQP-GIENEEAAA----IARAAGIRVV 106


                  ....*....
gi 1756860160  89 GPNCPGVIN 97
Cdd:pfam13380 107 GDRCLGVEH 115
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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