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Conserved domains on  [gi|1753147357|ref|XP_030896703|]
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golgin subfamily A member 4 isoform X1 [Leptonychotes weddellii]

Protein Classification

SMC_prok_B and Grip domain-containing protein( domain architecture ID 13279029)

protein containing domains PTZ00121, SMC_prok_B, and Grip

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 666-1377 6.60e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 6.60e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  666 KTELESLQHqqdTLWTEKLQVLKQE-HQTEMEKLREKHEQEK-ETLLKDKESLFQAHIEEMNEKTfEKLDVKQTELEsls 743
Cdd:TIGR02168  219 KAELRELEL---ALLVLRLEELREElEELQEELKEAEEELEElTAELQELEEKLEELRLEVSELE-EEIEELQKELY--- 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  744 selsDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESiiKEQEMSIQRTEKELKDEINQLGLLLKEKDK 823
Cdd:TIGR02168  292 ----ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL--AEELAELEEKLEELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  824 HLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETEriLLTEQVAEVETQKK 903
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK--LEEAELKELQAELE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  904 DVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYEsqlrdtnteQAQTKQNLIEKENVILQMREGQSKEIETLKQK 983
Cdd:TIGR02168  444 ELEEELEELQEELERLEEALEELREELEEAEQALDAAER---------ELAQLQARLDSLERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  984 LSAKEDSFSVLHEEYEIKfKNQEKKMEKI------------KQKAKEMQETLKKKLLDQEAKL------KKELENTVLEL 1045
Cdd:TIGR02168  515 QSGLSGILGVLSELISVD-EGYEAAIEAAlggrlqavvvenLNAAKKAIAFLKQNELGRVTFLpldsikGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1046 SQKEKQFNAKILEMAQA-------------------------NSAGISDAVSRLETNQKEQI-------------ESLTE 1087
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFdpklrkalsyllggvlvvddldnalELAKKLRPGYRIVTLDGDLVrpggvitggsaktNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1088 VHRRELSDVvsvwEKRLNQQAEELQEQhEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQ 1167
Cdd:TIGR02168  674 ERRREIEEL----EEKIEELEEKIAEL-EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1168 LHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHER 1247
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1248 NEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAKTNelinissnkINAILARISHCQNHTTKVKEALviktckaSEL 1327
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL---------IEELESELEALLNERASLEEAL-------ALL 892

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1328 EAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQ 1377
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1422-2145 9.20e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 9.20e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1422 ISSLSKQLTDLNTQLQNS-ISLTEKEAAISSLSKRYEEQQRELlgqvQDLSLKVETLSKEKVSALEQVDHLSNKFSEwkk 1500
Cdd:TIGR02168  248 LKEAEEELEELTAELQELeEKLEELRLEVSELEEEIEELQKEL----YALANEISRLEQQKQILRERLANLERQLEE--- 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1501 kaqskfiqYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETeLKTQTARI 1580
Cdd:TIGR02168  321 --------LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET-LRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1581 VELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQH-----IQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELE 1655
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaelkeLQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1656 TKKKELEHANSGMKGKEEELKALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGE-----L 1730
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrlqavV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1731 NTKLQEKEREIQVLEEK-----------LQSVEGPPQSEASAVPRSAEHMAACAEQEEAglqgcvQKAYEDKVSALQRSL 1799
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKF------DPKLRKALSYLLGGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1800 MEKEKLLQRLEQEKEE-------------------MVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELEEKSK 1860
Cdd:TIGR02168  626 LVVDDLDNALELAKKLrpgyrivtldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1861 NYSLIASQHVEEEGGKNNIGAKQNLEnvvddvQKTLQEKELACQILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQA 1940
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISAL------RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1941 LQQQMEgknkpteALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELD 2020
Cdd:TIGR02168  780 AEAEIE-------ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2021 IMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAEL------LESHQEETN 2094
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELeelrekLAQLELRLE 932

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 2095 QLYKKIAEKEDDLQRTAKRYEEILDAREEEMTAKVMDLQTQLEELQNKYQE 2145
Cdd:TIGR02168  933 GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
PTZ00121 super family cl31754
MAEBL; Provisional
 340-925 4.83e-14

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 78.64  E-value: 4.83e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  340 QRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMV 419
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  420 I---AETKRQMHEtLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIK 496
Cdd:PTZ00121  1307 AkkkAEEAKKADE-AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  497 AIEKTREEERTSLQLELSRVKQEAV----------DVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKI 566
Cdd:PTZ00121  1386 KAEEKKKADEAKKKAEEDKKKADELkkaaaakkkaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  567 ALEKSQSEYLKITQEKEQQESLALEELELQKK----AILMESENKLRDLQQEAETYRtRILELESSLEKSLQESKNQSED 642
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKkadeAKKAAEAKKKADEAKKAEEAK-KADEAKKAEEAKKADEAKKAEE 1544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  643 LAihlEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIE 722
Cdd:PTZ00121  1545 KK---KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK 1621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  723 EMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQvesiiKEQEMSIQR 802
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE-----KKAAEALKK 1696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  803 TEKElkdeinqlglllKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEH---LAQLQQ 879
Cdd:PTZ00121  1697 EAEE------------AKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEkkkIAHLKK 1764

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1753147357  880 KLLDLETERILLTEQVAEVETQKKDVCTELDTHKiQVRDLLQQLEN 925
Cdd:PTZ00121  1765 EEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK-KIKDIFDNFAN 1809
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2227-2270 5.30e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.07  E-value: 5.30e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1753147357  2227 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2270
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
mukB super family cl35272
chromosome partition protein MukB;
192-458 4.74e-04

chromosome partition protein MukB;


The actual alignment was detected with superfamily member PRK04863:

Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 4.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  192 EQLIQLLRR----MERRLNSYKGKCSEFVIAYQTLQREKKKLQGILSQS----QDKALRRIGELREELQMDQQAKKHLQ- 262
Cdd:PRK04863   836 EAELRQLNRrrveLERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllaDETLADRVEEIREQLDEAEEAKRFVQq 915

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  263 --------EEFDASLEEKDQHISVLQTQVSLLKQRLRNGPMNVDLPKPFPQmepQAEGVSKENTDGDIepvvvdGASAKT 334
Cdd:PRK04863   916 hgnalaqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEML------AKNSDL 986

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  335 LEVLQQRVKRQENLLQRCKETIQSHKEQC-------ALLTSEKEALQEQLDERLQELEKM--------KELHMAEKTKLI 399
Cdd:PRK04863   987 NEKLRQRLEQAEQERTRAREQLRQAQAQLaqynqvlASLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELH 1066

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357  400 TQLRDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTAQGEELREQ 458
Cdd:PRK04863  1067 ARLSANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 666-1377 6.60e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 6.60e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  666 KTELESLQHqqdTLWTEKLQVLKQE-HQTEMEKLREKHEQEK-ETLLKDKESLFQAHIEEMNEKTfEKLDVKQTELEsls 743
Cdd:TIGR02168  219 KAELRELEL---ALLVLRLEELREElEELQEELKEAEEELEElTAELQELEEKLEELRLEVSELE-EEIEELQKELY--- 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  744 selsDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESiiKEQEMSIQRTEKELKDEINQLGLLLKEKDK 823
Cdd:TIGR02168  292 ----ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL--AEELAELEEKLEELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  824 HLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETEriLLTEQVAEVETQKK 903
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK--LEEAELKELQAELE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  904 DVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYEsqlrdtnteQAQTKQNLIEKENVILQMREGQSKEIETLKQK 983
Cdd:TIGR02168  444 ELEEELEELQEELERLEEALEELREELEEAEQALDAAER---------ELAQLQARLDSLERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  984 LSAKEDSFSVLHEEYEIKfKNQEKKMEKI------------KQKAKEMQETLKKKLLDQEAKL------KKELENTVLEL 1045
Cdd:TIGR02168  515 QSGLSGILGVLSELISVD-EGYEAAIEAAlggrlqavvvenLNAAKKAIAFLKQNELGRVTFLpldsikGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1046 SQKEKQFNAKILEMAQA-------------------------NSAGISDAVSRLETNQKEQI-------------ESLTE 1087
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFdpklrkalsyllggvlvvddldnalELAKKLRPGYRIVTLDGDLVrpggvitggsaktNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1088 VHRRELSDVvsvwEKRLNQQAEELQEQhEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQ 1167
Cdd:TIGR02168  674 ERRREIEEL----EEKIEELEEKIAEL-EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1168 LHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHER 1247
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1248 NEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAKTNelinissnkINAILARISHCQNHTTKVKEALviktckaSEL 1327
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL---------IEELESELEALLNERASLEEAL-------ALL 892

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1328 EAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQ 1377
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942
PTZ00121 PTZ00121
MAEBL; Provisional
 369-1148 1.17e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 1.17e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  369 EKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 448
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  449 TAQGEELREQKE--KSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKK 526
Cdd:PTZ00121  1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  527 SSEQIVKLQKLHEEELASKEQELTKkfqTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKK---AILME 603
Cdd:PTZ00121  1261 RMAHFARRQAAIKAEEARKADELKK---AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  604 SENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDL----AIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTL 679
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKkkadAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  680 WTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKAR---NKL 756
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKaeeAKK 1497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  757 EEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSiQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLE 836
Cdd:PTZ00121  1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAK-KAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  837 ADIKRSEEELQQASAK-----LALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKK--DVCTEL 909
Cdd:PTZ00121  1577 NMALRKAEEAKKAEEArieevMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKaeELKKAE 1656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  910 DTHKIQVRDLLQQLENQKSEMEE-KLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMREGQSKEIETLKQK---LS 985
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKAEEaKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKaeeAK 1736

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  986 AKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQF---NAKILEMAQA 1062
Cdd:PTZ00121  1737 KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKE 1816

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1063 NSAGISDAVSRLETNQKEQIESLTEVhrRELSDVV--------SVWEKRLNQQAEELQEQHEIQLQEKEQEVAELKQKIL 1134
Cdd:PTZ00121  1817 GNLVINDSKEMEDSAIKEVADSKNMQ--LEEADAFekhkfnknNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKID 1894

                          810
                   ....*....|....
gi 1753147357 1135 RSACEKEEMNRELA 1148
Cdd:PTZ00121  1895 KDDIEREIPNNNMA 1908
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1422-2145 9.20e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 9.20e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1422 ISSLSKQLTDLNTQLQNS-ISLTEKEAAISSLSKRYEEQQRELlgqvQDLSLKVETLSKEKVSALEQVDHLSNKFSEwkk 1500
Cdd:TIGR02168  248 LKEAEEELEELTAELQELeEKLEELRLEVSELEEEIEELQKEL----YALANEISRLEQQKQILRERLANLERQLEE--- 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1501 kaqskfiqYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETeLKTQTARI 1580
Cdd:TIGR02168  321 --------LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET-LRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1581 VELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQH-----IQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELE 1655
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaelkeLQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1656 TKKKELEHANSGMKGKEEELKALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGE-----L 1730
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrlqavV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1731 NTKLQEKEREIQVLEEK-----------LQSVEGPPQSEASAVPRSAEHMAACAEQEEAglqgcvQKAYEDKVSALQRSL 1799
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKF------DPKLRKALSYLLGGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1800 MEKEKLLQRLEQEKEE-------------------MVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELEEKSK 1860
Cdd:TIGR02168  626 LVVDDLDNALELAKKLrpgyrivtldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1861 NYSLIASQHVEEEGGKNNIGAKQNLEnvvddvQKTLQEKELACQILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQA 1940
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISAL------RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1941 LQQQMEgknkpteALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELD 2020
Cdd:TIGR02168  780 AEAEIE-------ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2021 IMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAEL------LESHQEETN 2094
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELeelrekLAQLELRLE 932

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 2095 QLYKKIAEKEDDLQRTAKRYEEILDAREEEMTAKVMDLQTQLEELQNKYQE 2145
Cdd:TIGR02168  933 GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 371-986 1.22e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 1.22e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  371 EALQEQLDERLQELEKMKElhmaektklitQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTA 450
Cdd:COG1196    192 EDILGELERQLEPLERQAE-----------KAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  451 QGEELREQKEKsEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAiektREEERTSLQLELSRVKQEAvdvmkkssEQ 530
Cdd:COG1196    261 ELAELEAELEE-LRLELEELELELEEAQAEEYELLAELARLEQDIAR----LEERRRELEERLEELEEEL--------AE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  531 IVKLQKLHEEELASKEQELTKkfQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAILmESENKLRD 610
Cdd:COG1196    328 LEEELEELEEELEELEEELEE--AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA-ELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  611 LQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDT-LWTEKLQVLKQ 689
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAaLLEAALAELLE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  690 EHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKAR-NKLEEELSVLKDQAD 768
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALqNIVVEDDEVAAAAIE 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  769 KVKQELEAKLDEqkshhqQQVESIIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAH--VENLEADIKRSEEEL 846
Cdd:COG1196    565 YLKAAKAGRATF------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTllGRTLVAARLEAALRR 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  847 QQASAKLALFQSQQSTTHEQAKASEEHLA-QLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLEN 925
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRrELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1753147357  926 QKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQmREGQSKEIETLKQKLSA 986
Cdd:COG1196    719 EELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 340-925 4.83e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 78.64  E-value: 4.83e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  340 QRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMV 419
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  420 I---AETKRQMHEtLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIK 496
Cdd:PTZ00121  1307 AkkkAEEAKKADE-AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  497 AIEKTREEERTSLQLELSRVKQEAV----------DVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKI 566
Cdd:PTZ00121  1386 KAEEKKKADEAKKKAEEDKKKADELkkaaaakkkaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  567 ALEKSQSEYLKITQEKEQQESLALEELELQKK----AILMESENKLRDLQQEAETYRtRILELESSLEKSLQESKNQSED 642
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKkadeAKKAAEAKKKADEAKKAEEAK-KADEAKKAEEAKKADEAKKAEE 1544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  643 LAihlEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIE 722
Cdd:PTZ00121  1545 KK---KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK 1621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  723 EMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQvesiiKEQEMSIQR 802
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE-----KKAAEALKK 1696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  803 TEKElkdeinqlglllKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEH---LAQLQQ 879
Cdd:PTZ00121  1697 EAEE------------AKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEkkkIAHLKK 1764

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1753147357  880 KLLDLETERILLTEQVAEVETQKKDVCTELDTHKiQVRDLLQQLEN 925
Cdd:PTZ00121  1765 EEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK-KIKDIFDNFAN 1809
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 365-901 3.26e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.74  E-value: 3.26e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  365 LLTSEKEALQEQLDERLQELEKmKELHMAEKTKLITQLRDAKNLIEQLEQDKGmviaETKRQMHETLEMKEEEIAQLRSR 444
Cdd:COG1196    236 ELEAELEELEAELEELEAELEE-LEAELAELEAELEELRLELEELELELEEAQ----AEEYELLAELARLEQDIARLEER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  445 IKQMTAQGEELREQKEKSEKAAfEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVM 524
Cdd:COG1196    311 RRELEERLEELEEELAELEEEL-EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  525 KKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEyLKITQEKEQQESLALEELELQKKAILMES 604
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE-EEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  605 ENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKL 684
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  685 QVLKQEHQTEMEKLREKHEQEKE--------TLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARNKL 756
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAgratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  757 EEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEinqlgLLLKEKDKHLKEQQAHVENLE 836
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE-----ELAERLAEEELELEEALLAEE 703

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357  837 ADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQ 901
Cdd:COG1196    704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
PTZ00121 PTZ00121
MAEBL; Provisional
 1478-2151 1.21e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.02  E-value: 1.21e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1478 SKEKVSALEQVDHLSNKFSEWKKKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMED 1557
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1558 KKsKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAE 1637
Cdd:PTZ00121  1163 AR-KAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1638 EKVSRLEKQVSSMKSELETKKKELEHANSGMKGKE----EELKALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQME 1713
Cdd:PTZ00121  1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEarkaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1714 EKEQQYKKDTEghlgELNTKLQEKEREIQVLEEKlqsvEGPPQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVS 1793
Cdd:PTZ00121  1322 KKAEEAKKKAD----AAKKKAEEAKKAAEAAKAE----AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1794 ALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRYQEllIKIEHAEAKQHEDQIMINHLQKELEEKSKNYSliASQHVEEE 1873
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE--KKKADEAKKKAEEAKKADEAKKKAEEAKKAEE--AKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1874 GGKNNIGAKQNLENVVDDVQKTLQEKELACQILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTE 1953
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD 1549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1954 ALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQ-EMEE 2032
Cdd:PTZ00121  1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAE 1629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2033 KIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAK 2112
Cdd:PTZ00121  1630 EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1753147357 2113 RYEE------ILDAREEEMTAKVMDLQTQLEELQNKYQERLQQEE 2151
Cdd:PTZ00121  1710 KEAEekkkaeELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE 1754
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1519-2141 3.51e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 3.51e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1519 QLELKTKEVSEKAEQIHSLKENLDQQNERLVclkgEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLN 1598
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1599 EALNKYNQQKDTEQKEMLQKLQHIQELGEEKDN---RVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEEL 1675
Cdd:COG1196    295 AELARLEQDIARLEERRRELEERLEELEEELAEleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1676 KALEDRLELESAAKLAELKKKAEQkiaaikKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQSVEgpp 1755
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAEL------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE--- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1756 qseasavprSAEHMAACAEQEEAGLqgcvqkayEDKVSALQRSLMEKEKLLQRLEQEKEEMVSshsemqgryQELLIKIE 1835
Cdd:COG1196    446 ---------EAAEEEAELEEEEEAL--------LELLAELLEEAALLEAALAELLEELAEAAA---------RLLLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1836 HAEAKQHEDQIMINHLQKELEEKSKNYSLIASQHVEEEGGKNNIGAKQNLENVVDDVQKTLQEKELACQILEQKIKELDS 1915
Cdd:COG1196    500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1916 CLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQ 1995
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1996 KLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMtiKETI 2075
Cdd:COG1196    660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE--REEL 737

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 2076 DKAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAKRYEEI-------------LDAREEEMTAKVMDLQTQLEELQN 2141
Cdd:COG1196    738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaieeyeeLEERYDFLSEQREDLEEARETLEE 816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 192-961 3.07e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 3.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  192 EQLIQLLRRMERRLNSYKgKCSEFVIAYQTLQREKKKLQGILSQSQDKALRrigELREELQMDQQAKKHLQEEFDASLEE 271
Cdd:TIGR02168  189 DRLEDILNELERQLKSLE-RQAEKAERYKELKAELRELELALLVLRLEELR---EELEELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  272 KDQHISVLQTQVSLLKQRLRNGpmnvdlpkpfpQMEPQAEGVSKENTDGDIEPVVVDGASA-KTLEVLQQRVKRQENLLQ 350
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEEL-----------QKELYALANEISRLEQQKQILRERLANLeRQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  351 RCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKElHMAEKTKLITQLRDAKNLIEQLEQdkgmVIAETKRQMHET 430
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELES-RLEELEEQLETLRSKVAQLELQIA----SLNNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  431 LEMKEEEIAQLRSRIKQmtaQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQ 510
Cdd:TIGR02168  409 LERLEDRRERLQQEIEE---LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  511 LELSRVKQEAVDVMKKSSEQI-VKLQKLHEEELASKEQELTKKFQTQErQFQEQMKIALEKSQSEYLKITQEKEQQESLA 589
Cdd:TIGR02168  486 QLQARLDSLERLQENLEGFSEgVKALLKNQSGLSGILGVLSELISVDE-GYEAAIEAALGGRLQAVVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  590 LEELELQKKAILMESENKLRDLQ-------QEAETYRTRILELESSLEK------------------------------- 631
Cdd:TIGR02168  565 LKQNELGRVTFLPLDSIKGTEIQgndreilKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvddldnalelakklrpg 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  632 --------------------------SLQESKNQSEDLAIHLEAEKNKhNKEITIMVEKHKTELESLQHQQDTLWTEKLQ 685
Cdd:TIGR02168  645 yrivtldgdlvrpggvitggsaktnsSILERRREIEELEEKIEELEEK-IAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  686 VLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKD 765
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  766 QADkvkqELEAKLDEQKSHHQQQvesiikeqemsiQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEE 845
Cdd:TIGR02168  804 ALD----ELRAELTLLNEEAANL------------RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  846 LQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLEN 925
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE 947

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1753147357  926 QKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIE 961
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 663-1462 4.24e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.83  E-value: 4.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  663 EKHKTELESLQHQQDTLWTEKLQVLKQEhqtEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESL 742
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLK---EQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  743 SSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSI---------QRTEKELKDEINQ 813
Cdd:pfam02463  253 IESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVddeeklkesEKEKKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  814 LGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTE 893
Cdd:pfam02463  333 EKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  894 QVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALT-----QRYESQLRDTNTEQAQTKQNLIEKENVILQ 968
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQElkllkDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  969 MREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEK-KMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQ 1047
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLgDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1048 KEKQFNAKILEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVA 1127
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1128 ELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQsaQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQ 1207
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR--RQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1208 ERMVELEMLAEKDKLKVFELTDKLKTTD--------AQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEA 1279
Cdd:pfam02463  731 QDKINEELKLLKQKIDEEEEEEEKSRLKkeekeeekSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1280 LLQAKTNELINISSNKINAILARISHCQNHTTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQI 1359
Cdd:pfam02463  811 KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELES 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1360 KSMKADIEGLvmEKEALQREGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNS 1439
Cdd:pfam02463  891 KEEKEKEEKK--ELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLA 968

                          810       820
                   ....*....|....*....|...
gi 1753147357 1440 ISLTEKEAAISSLSKRYEEQQRE 1462
Cdd:pfam02463  969 KEELGKVNLMAIEEFEEKEERYN 991
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2227-2270 5.30e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.07  E-value: 5.30e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1753147357  2227 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2270
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1586-2202 2.23e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 2.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1586 HLTQKITEIESLNEALNKYNQQKdteQKEMLQKLQ-HIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHA 1664
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNK---IELLLQQHQdRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQ 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1665 NSGMKGKEEELKALEDRLELEsaakLAELKKKAEQKIAAIKKQLLSQMEEkeqqykkdteghLGELNTKLQEKEREIQVL 1744
Cdd:pfam15921  312 NSMYMRQLSDLESTVSQLRSE----LREAKRMYEDKIEELEKQLVLANSE------------LTEARTERDQFSQESGNL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1745 EEKLQSVEGPPQSEASAVPRSAEHMAACAEQEEAGlqgcvqkayEDKVSALQRSLMEKEKLLQRLEQEKEEMvssHSEMQ 1824
Cdd:pfam15921  376 DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGN---------SITIDHLRRELDDRNMEVQRLEALLKAM---KSECQ 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1825 GRYQELLIKIEhaeaKQHEDQIMINHLQKELEEKSKnyslIASQHVEEEGGKNNigAKQNLENVVDDVQKTLQEKELACQ 1904
Cdd:pfam15921  444 GQMERQMAAIQ----GKNESLEKVSSLTAQLESTKE----MLRKVVEELTAKKM--TLESSERTVSDLTASLQEKERAIE 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1905 ILEQKIKELDSCL---VREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHN 1981
Cdd:pfam15921  514 ATNAEITKLRSRVdlkLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKA 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1982 DLEFKLAGAEQEKQKLgkEIVKLQKDLRMLRKEHQ-QELDIMKKEYEQEMEEK------IKQEQEDL--ELKHN-STLKQ 2051
Cdd:pfam15921  594 QLEKEINDRRLELQEF--KILKDKKDAKIRELEARvSDLELEKVKLVNAGSERlravkdIKQERDQLlnEVKTSrNELNS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2052 LMREFHT---QLAQKDQELEMTIKETIDKAQDVEAELleshqEETNQLYKKIAEKEDDLQRTAKryeeildAREEEMTAK 2128
Cdd:pfam15921  672 LSEDYEVlkrNFRNKSEEMETTTNKLKMQLKSAQSEL-----EQTRNTLKSMEGSDGHAMKVAM-------GMQKQITAK 739

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1753147357 2129 vmdlQTQLEELQNKYQERLQQEESPGNDKITIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNV 2202
Cdd:pfam15921  740 ----RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 225-1062 4.06e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 4.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  225 EKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQHISVLQTQVSLLKQRLRNGPMNVDLPKPFP 304
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  305 QMEPQAEGVSKEntdgdiepvvvdgasaktlevLQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQEL 384
Cdd:pfam02463  254 ESSKQEIEKEEE---------------------KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  385 EKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSE- 463
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKl 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  464 ----KAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKL-H 538
Cdd:pfam02463  393 keeeLELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSeD 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  539 EEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETY 618
Cdd:pfam02463  473 LLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  619 RTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKL 698
Cdd:pfam02463  553 VSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDT 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  699 REKHEQEKEtllKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKL 778
Cdd:pfam02463  633 ELTKLKESA---KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  779 DEQKSHHQQQVESIIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQS 858
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  859 QQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALT 938
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  939 QRYESQLRDT-------NTEQAQTKQNLIEKENVILQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEK 1011
Cdd:pfam02463  870 QELLLKEEELeeqklkdELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 1012 IKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQA 1062
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERL 1000
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2228-2267 1.18e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 44.27  E-value: 1.18e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1753147357 2228 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2267
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 806-1077 7.18e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 48.29  E-value: 7.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  806 ELKDEINQLGLLLKEkDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEehlAQLQQKLLDLE 885
Cdd:NF012221  1539 ESSQQADAVSKHAKQ-DDAAQNALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETN---GQAQRDAILEE 1614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  886 TERIllTEQVAEVeTQKKDVCTELDTHKIQ-------------VRDLLQQLENQKSEMEEKLQALTQRYESQLRD----- 947
Cdd:NF012221  1615 SRAV--TKELTTL-AQGLDALDSQATYAGEsgdqwrnpfagglLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKvkdav 1691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  948 --TNTEQAQTKQNLIEKENVILQMR-EGQSKEIETLKQKLSAKE---DSFSVLHEEY---EIKFKNQEKKMEKIKQKAKE 1018
Cdd:NF012221  1692 akSEAGVAQGEQNQANAEQDIDDAKaDAEKRKDDALAKQNEAQQaesDANAAANDAQsrgEQDASAAENKANQAQADAKG 1771

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1753147357 1019 MQET--------------LKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANSAGISDAVSRLETN 1077
Cdd:NF012221  1772 AKQDesdkpnrqgaagsgLSGKAYSVEGVAEPGSHINPDSPAAADGRFSEGLTEQEQEALEGATNAVNRLQIN 1844
mukB PRK04863
chromosome partition protein MukB;
192-458 4.74e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 4.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  192 EQLIQLLRR----MERRLNSYKGKCSEFVIAYQTLQREKKKLQGILSQS----QDKALRRIGELREELQMDQQAKKHLQ- 262
Cdd:PRK04863   836 EAELRQLNRrrveLERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllaDETLADRVEEIREQLDEAEEAKRFVQq 915

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  263 --------EEFDASLEEKDQHISVLQTQVSLLKQRLRNGPMNVDLPKPFPQmepQAEGVSKENTDGDIepvvvdGASAKT 334
Cdd:PRK04863   916 hgnalaqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEML------AKNSDL 986

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  335 LEVLQQRVKRQENLLQRCKETIQSHKEQC-------ALLTSEKEALQEQLDERLQELEKM--------KELHMAEKTKLI 399
Cdd:PRK04863   987 NEKLRQRLEQAEQERTRAREQLRQAQAQLaqynqvlASLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELH 1066

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357  400 TQLRDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTAQGEELREQ 458
Cdd:PRK04863  1067 ARLSANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 666-1377 6.60e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 6.60e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  666 KTELESLQHqqdTLWTEKLQVLKQE-HQTEMEKLREKHEQEK-ETLLKDKESLFQAHIEEMNEKTfEKLDVKQTELEsls 743
Cdd:TIGR02168  219 KAELRELEL---ALLVLRLEELREElEELQEELKEAEEELEElTAELQELEEKLEELRLEVSELE-EEIEELQKELY--- 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  744 selsDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESiiKEQEMSIQRTEKELKDEINQLGLLLKEKDK 823
Cdd:TIGR02168  292 ----ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL--AEELAELEEKLEELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  824 HLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETEriLLTEQVAEVETQKK 903
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK--LEEAELKELQAELE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  904 DVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYEsqlrdtnteQAQTKQNLIEKENVILQMREGQSKEIETLKQK 983
Cdd:TIGR02168  444 ELEEELEELQEELERLEEALEELREELEEAEQALDAAER---------ELAQLQARLDSLERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  984 LSAKEDSFSVLHEEYEIKfKNQEKKMEKI------------KQKAKEMQETLKKKLLDQEAKL------KKELENTVLEL 1045
Cdd:TIGR02168  515 QSGLSGILGVLSELISVD-EGYEAAIEAAlggrlqavvvenLNAAKKAIAFLKQNELGRVTFLpldsikGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1046 SQKEKQFNAKILEMAQA-------------------------NSAGISDAVSRLETNQKEQI-------------ESLTE 1087
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFdpklrkalsyllggvlvvddldnalELAKKLRPGYRIVTLDGDLVrpggvitggsaktNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1088 VHRRELSDVvsvwEKRLNQQAEELQEQhEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQ 1167
Cdd:TIGR02168  674 ERRREIEEL----EEKIEELEEKIAEL-EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1168 LHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHER 1247
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1248 NEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAKTNelinissnkINAILARISHCQNHTTKVKEALviktckaSEL 1327
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL---------IEELESELEALLNERASLEEAL-------ALL 892

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1328 EAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQ 1377
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 987-1718 5.10e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 5.10e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  987 KEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKkLLDQEAKLKKELENTVLELSQKEKQFNAkilemAQANSAG 1066
Cdd:TIGR02168  219 KAELRELELALLVLRLEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRLEVSELEEEIEE-----LQKELYA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1067 ISDAVSRLETNQKEQIESLTEVHRRelsdvvsvwekrlNQQAEELQEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRE 1146
Cdd:TIGR02168  293 LANEISRLEQQKQILRERLANLERQ-------------LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1147 LAWLKEEGVKQNTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKvfE 1226
Cdd:TIGR02168  360 LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK--E 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1227 LTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEE-----------------LAVQLEIYSKKTEALLQAKTN--- 1286
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQAldaaerelaqlqarldsLERLQENLEGFSEGVKALLKNqsg 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1287 ---------ELINISSNKINAILARI-SHCQNHTTKVKEA------------------LVIKTCKASELEAQLRQLTEEQ 1338
Cdd:TIGR02168  518 lsgilgvlsELISVDEGYEAAIEAALgGRLQAVVVENLNAakkaiaflkqnelgrvtfLPLDSIKGTEIQGNDREILKNI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1339 NtlnsSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQ-----------------------REGGNQQQAASEKESCIT 1395
Cdd:TIGR02168  598 E----GFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDnalelakklrpgyrivtldgdlvRPGGVITGGSAKTNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1396 QLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQL-QNSISLTEKEAAISSLSKRY---EEQQRELLGQVQDLS 1471
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELeQLRKELEELSRQISALRKDLarlEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1472 LKVETLSKEKVSALEQVDHLSNKFSEWKKKAQskfiQYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCL 1551
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1552 KGEMEDKKSKLEkkecNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGE---E 1628
Cdd:TIGR02168  830 ERRIAATERRLE----DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrE 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1629 KDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEH----ANSGMKGKEEELKALEDRLELESAAKLAELkKKAEQKIAAI 1704
Cdd:TIGR02168  906 LESKRSELRRELEELREKLAQLELRLEGLEVRIDNlqerLSEEYSLTLEEAEALENKIEDDEEEARRRL-KRLENKIKEL 984

                          810
                   ....*....|....
gi 1753147357 1705 KKQLLSQMEEKEQQ 1718
Cdd:TIGR02168  985 GPVNLAAIEEYEEL 998
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 335-1025 5.99e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.80  E-value: 5.99e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  335 LEVLQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDE-RLQELEKMKELHMAEKTklitqLRDAKNLIEQLE 413
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  414 QDKgMVIAETKRQMHETLEMKEEEIAQLRSRI-------KQMTAQGEELREQKE------KSEKAAFEELEKALSTAQKA 480
Cdd:TIGR02168  302 QQK-QILRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  481 EESWRKMKAEVDEQIKAIEKTR---EEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQE 557
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIerlEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  558 RQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILEL-------ESSLE 630
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  631 KSLQES-------KNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLK--------------- 688
Cdd:TIGR02168  541 AALGGRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsy 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  689 --------QEHQTEMEKLREKHEQE-----KETLLKDKESLFQAHiEEMNEKTFEK---LDVKQTELESLSSELSDILKA 752
Cdd:TIGR02168  621 llggvlvvDDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGS-AKTNSSILERrreIEELEEKIEELEEKIAELEKA 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  753 RNKLEEELSVLKDQADKVKQELEAK------LDEQKSHHQQQVESIIKEQEmSIQRTEKELKDEINQLGLLLKEKDKHLK 826
Cdd:TIGR02168  700 LAELRKELEELEEELEQLRKELEELsrqisaLRKDLARLEAEVEQLEERIA-QLSKELTELEAEIEELEERLEEAEEELA 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  827 EQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVC 906
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  907 TELDTHKIQVRDL---LQQLENQKSEMEEKLQALTQRYES---QLRDTNTEQAQTKQNLIEKENVILQMREGQSK---EI 977
Cdd:TIGR02168  859 AEIEELEELIEELeseLEALLNERASLEEALALLRSELEElseELRELESKRSELRRELEELREKLAQLELRLEGlevRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1753147357  978 ETLKQKLSakedsfsvlhEEYEIKFKNQEKKMEKIKQKAKEMQETLKK 1025
Cdd:TIGR02168  939 DNLQERLS----------EEYSLTLEEAEALENKIEDDEEEARRRLKR 976
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 749-1540 1.42e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 86.66  E-value: 1.42e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  749 ILKARNKLEEELSVLKDQADKVKQELEaKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEINQLglllkekDKHLKEQ 828
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELE-KLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-------KEKIGEL 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  829 QAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTE 908
Cdd:TIGR02169  300 EAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  909 LDTHKIQVRDLLQQLENQKSEMEE------KLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMR---EGQSKEIET 979
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINElkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAleiKKQEWKLEQ 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  980 LKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQ--ETLKKKLLDQEAKLKKELEN---TVLELSQKEKQFnA 1054
Cdd:TIGR02169  460 LAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARasEERVRGGRAVEEVLKASIQGvhgTVAQLGSVGERY-A 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1055 KILEMAQANSAGisDAVSRLETNQKEQIESLTEVHRRELS----DVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVAELK 1130
Cdd:TIGR02169  539 TAIEVAAGNRLN--NVVVEDDAVAKEAIELLKRRKAGRATflplNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAF 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1131 QKILRSACEKEEMnrELAWLKEEGVKQNTAVRELQEQ---LHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQ 1207
Cdd:TIGR02169  617 KYVFGDTLVVEDI--EAARRLMGKYRMVTLEGELFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1208 ERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAvQLEIYSKKTEALLQAKTNE 1287
Cdd:TIGR02169  695 SELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE-NVKSELKELEARIEELEED 773

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1288 LINISSnKINAILARISH-----CQNHTTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSM 1362
Cdd:TIGR02169  774 LHKLEE-ALNDLEARLSHsripeIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1363 KADIEGLVMEKEALQREGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNsisL 1442
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA---L 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1443 TEKEAAISSLSKRYEEQQREL--LGQVQDLSLKVEtlskEKVSALEQVDHLSNKFSEWKKKAQSKFiqyhstnKELQMQL 1520
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEElsLEDVQAELQRVE----EEIRALEPVNMLAIQEYEEVLKRLDEL-------KEKRAKL 998

                          810       820
                   ....*....|....*....|
gi 1753147357 1521 ELKTKEVSEKAEQIHSLKEN 1540
Cdd:TIGR02169  999 EEERKAILERIEEYEKKKRE 1018
PTZ00121 PTZ00121
MAEBL; Provisional
 369-1148 1.17e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 1.17e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  369 EKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 448
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  449 TAQGEELREQKE--KSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKK 526
Cdd:PTZ00121  1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  527 SSEQIVKLQKLHEEELASKEQELTKkfqTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKK---AILME 603
Cdd:PTZ00121  1261 RMAHFARRQAAIKAEEARKADELKK---AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  604 SENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDL----AIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTL 679
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKkkadAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  680 WTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKAR---NKL 756
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKaeeAKK 1497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  757 EEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSiQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLE 836
Cdd:PTZ00121  1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAK-KAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  837 ADIKRSEEELQQASAK-----LALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKK--DVCTEL 909
Cdd:PTZ00121  1577 NMALRKAEEAKKAEEArieevMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKaeELKKAE 1656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  910 DTHKIQVRDLLQQLENQKSEMEE-KLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMREGQSKEIETLKQK---LS 985
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKAEEaKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKaeeAK 1736

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  986 AKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQF---NAKILEMAQA 1062
Cdd:PTZ00121  1737 KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKE 1816

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1063 NSAGISDAVSRLETNQKEQIESLTEVhrRELSDVV--------SVWEKRLNQQAEELQEQHEIQLQEKEQEVAELKQKIL 1134
Cdd:PTZ00121  1817 GNLVINDSKEMEDSAIKEVADSKNMQ--LEEADAFekhkfnknNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKID 1894

                          810
                   ....*....|....
gi 1753147357 1135 RSACEKEEMNRELA 1148
Cdd:PTZ00121  1895 KDDIEREIPNNNMA 1908
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 373-1133 4.41e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 4.41e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  373 LQEQLDERLQELEKmkELHMAEKTKLITQLRDAKNLIEQLEQDKGMViAETKRQMHETLEMKEEEIAQLRSRIKQMTAQG 452
Cdd:TIGR02168  207 RQAEKAERYKELKA--ELRELELALLVLRLEELREELEELQEELKEA-EEELEELTAELQELEEKLEELRLEVSELEEEI 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  453 EELrEQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEertsLQLELSRVKQEAVDVMKKSSEQIV 532
Cdd:TIGR02168  284 EEL-QKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE----LAEELAELEEKLEELKEELESLEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  533 KLQKLHE--EELASKEQELTKKFQTQER-QFQEQMKIALEKSQSEYLKItqEKEQQESLALEELELQKKAILMESENKLR 609
Cdd:TIGR02168  359 ELEELEAelEELESRLEELEEQLETLRSkVAQLELQIASLNNEIERLEA--RLERLEDRRERLQQEIEELLKKLEEAELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  610 DLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKteLESLQHQQDTLWTEKLQVLKQ 689
Cdd:TIGR02168  437 ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS--LERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  690 EHQ--------TEMEKLREKHEQEKETLL---------KDKESLFQA------------HIEEMNEKTFEKLDVKQTELE 740
Cdd:TIGR02168  515 QSGlsgilgvlSELISVDEGYEAAIEAALggrlqavvvENLNAAKKAiaflkqnelgrvTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  741 SLSSELSDILKARNKLEEELSVLKD---QADKVKQELEAKLDEQKSHHQQqvESII-----------------KEQEMSI 800
Cdd:TIGR02168  595 KNIEGFLGVAKDLVKFDPKLRKALSyllGGVLVVDDLDNALELAKKLRPG--YRIVtldgdlvrpggvitggsAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  801 QRTEKELKD---EINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQL 877
Cdd:TIGR02168  673 LERRREIEEleeKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  878 QQKLLDLETERILLTEQVAEVETQKKdvctELDTHKIQVRDLLQQLENQKSEMEEKLQALtqryESQLRDTNTEQAQTKQ 957
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELA----EAEAEIEELEAQIEQLKEELKALREALDEL----RAELTLLNEEAANLRE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  958 NLIEKENVIlQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKiKQKAKEMQETLKKKLLDQEAKLKKE 1037
Cdd:TIGR02168  825 RLESLERRI-AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-LLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1038 LENTVLELSQKEKQFNAKILEMAQANSagisdAVSRLETNQKEQIESLTEVHRRELsdvvsvwekrlnQQAEELQEQHEI 1117
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLEL-----RLEGLEVRIDNLQERLSEEYSLTL------------EEAEALENKIED 965

                          810
                   ....*....|....*.
gi 1753147357 1118 QLQEKEQEVAELKQKI 1133
Cdd:TIGR02168  966 DEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 752-1650 7.38e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 7.38e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  752 ARNKLEEELSVLKDQADKVKQELEakLDEQKSHHQQQVESIIKEQEmsiQRTEKELKDEINQLGLLLKEKDKHLKEQQAH 831
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKE--LKAELRELELALLVLRLEEL---REELEELQEELKEAEEELEELTAELQELEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  832 VENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETErillteqvaevetqkkdvcteldt 911
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ------------------------ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  912 hkiqvrdlLQQLENQKSEMEEKLQALTQRYEsqlrdtnteqaqtkqnliekenvilqmregqskEIETLKQKLSAKEDSF 991
Cdd:TIGR02168  325 --------LEELESKLDELAEELAELEEKLE---------------------------------ELKEELESLEAELEEL 363

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  992 SVLHEEYEIKFKNQEKKMEKIKQKAKEMQEtlkkklldQEAKLKKELENTVLELSQkekqfnakilemaqansagISDAV 1071
Cdd:TIGR02168  364 EAELEELESRLEELEEQLETLRSKVAQLEL--------QIASLNNEIERLEARLER-------------------LEDRR 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1072 SRLETNQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEELqEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLK 1151
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1152 ---EEGVKQNTAVRELQEQLHQQSAQTNSLSQN---ETKLKAQLEK-LEGDLNHSLRENTSLQERMVELEMLAEKDKLKV 1224
Cdd:TIGR02168  496 rlqENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAaLGGRLQAVVVENLNAAKKAIAFLKQNELGRVTF 575

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1225 FELTD----KLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAK-----------TNELI 1289
Cdd:TIGR02168  576 LPLDSikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKklrpgyrivtlDGDLV 655

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1290 NI-------SSNKINAILARISHCQNHTTKVKEALViktcKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSM 1362
Cdd:TIGR02168  656 RPggvitggSAKTNSSILERRREIEELEEKIEELEE----KIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL 731

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1363 KADIEGLVMEKEALQREGGNQQQAASEKESCITQLKKELSENinavtlmKEELKEKKSEISSLSKQLTDLNTQLQNSisl 1442
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA-------EEELAEAEAEIEELEAQIEQLKEELKAL--- 801

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1443 tekEAAISSLSKRYEEQQRELlgqvQDLSLKVETLSKEKVSALEQVDHLSNKF---SEWKKKAQSKFIQYHSTNKELQMQ 1519
Cdd:TIGR02168  802 ---REALDELRAELTLLNEEA----ANLRERLESLERRIAATERRLEDLEEQIeelSEDIESLAAEIEELEELIEELESE 874

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1520 LELKTKEVSEKAEQIHSLKENLDQQNERLvclkGEMEDKKSKLEKkecnletELKTQTARIVELQEHLTQKITEIESLNE 1599
Cdd:TIGR02168  875 LEALLNERASLEEALALLRSELEELSEEL----RELESKRSELRR-------ELEELREKLAQLELRLEGLEVRIDNLQE 943

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 1600 ALNkyNQQKDTeqkemlqkLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSM 1650
Cdd:TIGR02168  944 RLS--EEYSLT--------LEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1422-2145 9.20e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 9.20e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1422 ISSLSKQLTDLNTQLQNS-ISLTEKEAAISSLSKRYEEQQRELlgqvQDLSLKVETLSKEKVSALEQVDHLSNKFSEwkk 1500
Cdd:TIGR02168  248 LKEAEEELEELTAELQELeEKLEELRLEVSELEEEIEELQKEL----YALANEISRLEQQKQILRERLANLERQLEE--- 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1501 kaqskfiqYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETeLKTQTARI 1580
Cdd:TIGR02168  321 --------LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET-LRSKVAQL 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1581 VELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQH-----IQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELE 1655
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaelkeLQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1656 TKKKELEHANSGMKGKEEELKALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGE-----L 1730
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrlqavV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1731 NTKLQEKEREIQVLEEK-----------LQSVEGPPQSEASAVPRSAEHMAACAEQEEAglqgcvQKAYEDKVSALQRSL 1799
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKF------DPKLRKALSYLLGGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1800 MEKEKLLQRLEQEKEE-------------------MVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELEEKSK 1860
Cdd:TIGR02168  626 LVVDDLDNALELAKKLrpgyrivtldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1861 NYSLIASQHVEEEGGKNNIGAKQNLEnvvddvQKTLQEKELACQILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQA 1940
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISAL------RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1941 LQQQMEgknkpteALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELD 2020
Cdd:TIGR02168  780 AEAEIE-------ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2021 IMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAEL------LESHQEETN 2094
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELeelrekLAQLELRLE 932

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 2095 QLYKKIAEKEDDLQRTAKRYEEILDAREEEMTAKVMDLQTQLEELQNKYQE 2145
Cdd:TIGR02168  933 GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 371-986 1.22e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 1.22e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  371 EALQEQLDERLQELEKMKElhmaektklitQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTA 450
Cdd:COG1196    192 EDILGELERQLEPLERQAE-----------KAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  451 QGEELREQKEKsEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAiektREEERTSLQLELSRVKQEAvdvmkkssEQ 530
Cdd:COG1196    261 ELAELEAELEE-LRLELEELELELEEAQAEEYELLAELARLEQDIAR----LEERRRELEERLEELEEEL--------AE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  531 IVKLQKLHEEELASKEQELTKkfQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAILmESENKLRD 610
Cdd:COG1196    328 LEEELEELEEELEELEEELEE--AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA-ELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  611 LQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDT-LWTEKLQVLKQ 689
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAaLLEAALAELLE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  690 EHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKAR-NKLEEELSVLKDQAD 768
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALqNIVVEDDEVAAAAIE 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  769 KVKQELEAKLDEqkshhqQQVESIIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAH--VENLEADIKRSEEEL 846
Cdd:COG1196    565 YLKAAKAGRATF------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTllGRTLVAARLEAALRR 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  847 QQASAKLALFQSQQSTTHEQAKASEEHLA-QLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLEN 925
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRrELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1753147357  926 QKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQmREGQSKEIETLKQKLSA 986
Cdd:COG1196    719 EELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1324-2139 2.78e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 2.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1324 ASELEAQLRQLtEEQNTLNSSFQQATRQLEEKE-----NQIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCITQLK 1398
Cdd:TIGR02168  195 LNELERQLKSL-ERQAEKAERYKELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1399 KELSEninavtlMKEELKEKKSEISSLSKQLTDLNTQLQnsiSLTEKEAAISSLSKRYEEQQRELLGQVQDLSLKVETLS 1478
Cdd:TIGR02168  274 LEVSE-------LEEEIEELQKELYALANEISRLEQQKQ---ILRERLANLERQLEELEAQLEELESKLDELAEELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1479 KEKVSALEQVDHLSNKFSEWKKKAQskfiqyhstnkELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDK 1558
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELE-----------ELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1559 KSKLEKKECNLETEL-KTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEkdnrVKEAE 1637
Cdd:TIGR02168  413 EDRRERLQQEIEELLkKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE----LAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1638 EKVSRLEKQVSSMKSELETKKKELEHAN----------SGMKGKEEELKALEDRLELESAAKLAELKKKAEQKIAAIKKQ 1707
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSglsgilgvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQN 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1708 LL-------------SQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQS---VEGPPQSEASAVPRSAEHMAA 1771
Cdd:TIGR02168  569 ELgrvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRPGYRIV 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1772 CAEQEEAGLQGCVQKAYEDKVSalqrSLMEKEKLLQRLEQEKEEMvsshsemQGRYQELLIKIEHAEAKQHEDQIMINHL 1851
Cdd:TIGR02168  649 TLDGDLVRPGGVITGGSAKTNS----SILERRREIEELEEKIEEL-------EEKIAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1852 QKELEEKSKNYSLIASQHVEEEGgknnigAKQNLENVVDDVQKTLQEKELACQILEQKIKELDSCLVREREghrvemeel 1931
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEA------EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA--------- 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1932 tskfeKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRML 2011
Cdd:TIGR02168  783 -----EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2012 RKEH-QQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTqLAQKDQELEMTIKETIDKAQDVEAELLESHQ 2090
Cdd:TIGR02168  858 AAEIeELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE-LESKRSELRRELEELREKLAQLELRLEGLEV 936

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1753147357 2091 EETNQLyKKIAEKEDDLQRTAKRYEEILDAREEEMTAKVMDLQTQLEEL 2139
Cdd:TIGR02168  937 RIDNLQ-ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 340-925 4.83e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 78.64  E-value: 4.83e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  340 QRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMV 419
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  420 I---AETKRQMHEtLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIK 496
Cdd:PTZ00121  1307 AkkkAEEAKKADE-AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  497 AIEKTREEERTSLQLELSRVKQEAV----------DVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKI 566
Cdd:PTZ00121  1386 KAEEKKKADEAKKKAEEDKKKADELkkaaaakkkaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  567 ALEKSQSEYLKITQEKEQQESLALEELELQKK----AILMESENKLRDLQQEAETYRtRILELESSLEKSLQESKNQSED 642
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKkadeAKKAAEAKKKADEAKKAEEAK-KADEAKKAEEAKKADEAKKAEE 1544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  643 LAihlEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIE 722
Cdd:PTZ00121  1545 KK---KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK 1621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  723 EMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQvesiiKEQEMSIQR 802
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE-----KKAAEALKK 1696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  803 TEKElkdeinqlglllKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEH---LAQLQQ 879
Cdd:PTZ00121  1697 EAEE------------AKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEkkkIAHLKK 1764

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1753147357  880 KLLDLETERILLTEQVAEVETQKKDVCTELDTHKiQVRDLLQQLEN 925
Cdd:PTZ00121  1765 EEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK-KIKDIFDNFAN 1809
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 422-1272 2.74e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.86  E-value: 2.74e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  422 ETKRQMHETlemkEEEIAQLRSRIKQMTAQGEELREQKEKSE-----KAAFEELEKALSTAQKaeESWRKMKAEVDEQIK 496
Cdd:TIGR02168  176 ETERKLERT----RENLDRLEDILNELERQLKSLERQAEKAErykelKAELRELELALLVLRL--EELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  497 AIEKTREEERTSLQLELSRV--KQEAVDVMKKSSEQIVKLQKLHEEELASKEQEltKKFQTQERQFQEQmkialeksQSE 574
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLeeLRLEVSELEEEIEELQKELYALANEISRLEQQ--KQILRERLANLER--------QLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  575 YLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAiHLEAEKNKH 654
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  655 NKEITIMvekhKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLfqahieemnektfekldv 734
Cdd:TIGR02168  399 NNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEL------------------ 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  735 kqteleslsselsdilkarNKLEEELSVLKDQADKVKQELEAKLDEQKsHHQQQVESI--IKEQEMSIQRTEKELKDEIN 812
Cdd:TIGR02168  457 -------------------ERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLerLQENLEGFSEGVKALLKNQS 516

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  813 QLGLLLkekdkhlkeqqahveNLEADIKRSEEELQQAsAKLALFQSQQSTTHEQAKASEEHLAQLQQKlldlETERILLT 892
Cdd:TIGR02168  517 GLSGIL---------------GVLSELISVDEGYEAA-IEAALGGRLQAVVVENLNAAKKAIAFLKQN----ELGRVTFL 576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  893 EQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYesqLRDTNTEQAQTKQNLIEKENVILqMREG 972
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV---LVVDDLDNALELAKKLRPGYRIV-TLDG 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  973 QSKEIETLKQKLSAKEDSfSVLHEEYEIkfKNQEKKMEKIKQKAKEMQETLkKKLLDQEAKLKKELENTVLELSQKEKQF 1052
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNS-SILERRREI--EELEEKIEELEEKIAELEKAL-AELRKELEELEEELEQLRKELEELSRQI 728

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1053 NA--KILEMAQANSAGISDAVSRLETNQKEQIESLTEVHRR------ELSDVVSVWEKrLNQQAEELQEQHEI---QLQE 1121
Cdd:TIGR02168  729 SAlrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERleeaeeELAEAEAEIEE-LEAQIEQLKEELKAlreALDE 807

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1122 KEQEVAELKQKILRSACEKEEMNRELAWLKEEgvkqntaVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLR 1201
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRIAATERR-------LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN 880

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 1202 ENTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEI 1272
Cdd:TIGR02168  881 ERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 365-901 3.26e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.74  E-value: 3.26e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  365 LLTSEKEALQEQLDERLQELEKmKELHMAEKTKLITQLRDAKNLIEQLEQDKGmviaETKRQMHETLEMKEEEIAQLRSR 444
Cdd:COG1196    236 ELEAELEELEAELEELEAELEE-LEAELAELEAELEELRLELEELELELEEAQ----AEEYELLAELARLEQDIARLEER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  445 IKQMTAQGEELREQKEKSEKAAfEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVM 524
Cdd:COG1196    311 RRELEERLEELEEELAELEEEL-EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  525 KKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEyLKITQEKEQQESLALEELELQKKAILMES 604
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE-EEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  605 ENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKL 684
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  685 QVLKQEHQTEMEKLREKHEQEKE--------TLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARNKL 756
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAgratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  757 EEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEinqlgLLLKEKDKHLKEQQAHVENLE 836
Cdd:COG1196    629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE-----ELAERLAEEELELEEALLAEE 703

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357  837 ADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQ 901
Cdd:COG1196    704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1093-1876 5.43e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 5.43e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1093 LSDVVSVWEKRLN------QQAEELQEQHE-----------IQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGV 1155
Cdd:TIGR02168  191 LEDILNELERQLKslerqaEKAERYKELKAelrelelallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1156 KQNTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKVFELTDKLKTTD 1235
Cdd:TIGR02168  271 ELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1236 AQFQSLQSSHERNEKSLEdkslEFKKLSEELAVQLEIYSKKteallQAKTNELINISSNKINAILARISHcqnhttkvke 1315
Cdd:TIGR02168  351 EELESLEAELEELEAELE----ELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLER---------- 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1316 alviktckaseLEAQLRQLTEEQNTLNSSFQQAtrQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCIT 1395
Cdd:TIGR02168  412 -----------LEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1396 QLKKELSENINAVTLMKEELKEKKSEISSLS------KQLTDLNTQLQNSISLTEK-EAAISSLskryeeqqreLLGQVQ 1468
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKallknqSGLSGILGVLSELISVDEGyEAAIEAA----------LGGRLQ 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1469 DLSLKVETLSKEKVSALEQVDHLSNKFSEWKKKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQIHSL----------K 1538
Cdd:TIGR02168  549 AVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1539 ENLDQ---------QNERLVCLKGEM------------EDKKSKLEKKE--CNLETELKTQTARIVELQehltQKITEIE 1595
Cdd:TIGR02168  629 DDLDNalelakklrPGYRIVTLDGDLvrpggvitggsaKTNSSILERRReiEELEEKIEELEEKIAELE----KALAELR 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1596 SLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEEL 1675
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1676 KALEDRLE-LESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEghlgELNTKLQEKEREIQVLEEKLQSVEGp 1754
Cdd:TIGR02168  785 EELEAQIEqLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA----ATERRLEDLEEQIEELSEDIESLAA- 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1755 pQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRYQELLIKI 1834
Cdd:TIGR02168  860 -EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1753147357 1835 EHAEAKQHEDQIMINHLQKELEEKSKNYSLIASQHVEEEGGK 1876
Cdd:TIGR02168  939 DNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1444-2196 5.57e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 5.57e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1444 EKEAAISSLSKRYEEQQREL------LGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEWKKKAQSKFIQYHSTNKELQ 1517
Cdd:TIGR02168  222 LRELELALLVLRLEELREELeelqeeLKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1518 MQLEL---KTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEI 1594
Cdd:TIGR02168  302 QQKQIlreRLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1595 ESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRL-EKQVSSMKSELETKKKELEHANSGMKGKEE 1673
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLeEAELKELQAELEELEEELEELQEELERLEE 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1674 ELKALEDRLElesAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQY----------KKDTEGHLGELNTKLQ---EKERE 1740
Cdd:TIGR02168  462 ALEELREELE---EAEQALDAAERELAQLQARLDSLERLQENLEGFsegvkallknQSGLSGILGVLSELISvdeGYEAA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1741 IQ-VLEEKLQSVEGppqSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRsLMEKEKLLQRLEQEKEEMVSS 1819
Cdd:TIGR02168  539 IEaALGGRLQAVVV---ENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKL 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1820 HSEMQGRYQELLIKIEHAEAkqhedqimiNHLQKELEEKSKNYSL----IASQHVEEEGGKNNIGAKQNLENVVDDVQKT 1895
Cdd:TIGR02168  615 RKALSYLLGGVLVVDDLDNA---------LELAKKLRPGYRIVTLdgdlVRPGGVITGGSAKTNSSILERRREIEELEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1896 LQEKELACQILEQKIKELdsclvrereghRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLP-- 1973
Cdd:TIGR02168  686 IEELEEKIAELEKALAEL-----------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLsk 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1974 --GNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQ---ELDIMKKEYEQEMEEKIKQEQEDLELKHNST 2048
Cdd:TIGR02168  755 elTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2049 LKQLMREFHTQLAQKDQELEMTIKETIDKAQdveaELLESHQEETNQLYKKIAEKEDDLQRTAKRYEEiLDAREEEMTAK 2128
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSEDIESLAAEIEELE----ELIEELESELEALLNERASLEEALALLRSELEE-LSEELRELESK 909

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 2129 VMDLQTQLEELQ---NKYQERLQQEEspgndkITIMELQTQLAQK--------TTLISDSKLKEQEFREQIHNLEDRLK 2196
Cdd:TIGR02168  910 RSELRRELEELReklAQLELRLEGLE------VRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 750-1564 7.55e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 7.55e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  750 LKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKE---QEMSIQRTEKELKDEINQLGLLLKEKDKHLK 826
Cdd:TIGR02168  205 LERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEaeeELEELTAELQELEEKLEELRLEVSELEEEIE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  827 EQQAHVENLEADIKRSEEELQQASAKLALFQSQQsttheqaKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVC 906
Cdd:TIGR02168  285 ELQKELYALANEISRLEQQKQILRERLANLERQL-------EELEAQLEELESKLDELAEELAELEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  907 TELDThkiqVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENvILQMREGQSKEIETLKQKLSA 986
Cdd:TIGR02168  358 AELEE----LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLER-LEDRRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  987 KEdsFSVLHEEYEikfknQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKekQFNAKILEMAQANSAG 1066
Cdd:TIGR02168  433 AE--LKELQAELE-----ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL--QARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1067 ISDAVSRLeTNQKEQIESLTEVhrreLSDVVSV---WEKRLNQQAEE-LQEQHEIQLQEKEQEVAELKQK--------IL 1134
Cdd:TIGR02168  504 FSEGVKAL-LKNQSGLSGILGV----LSELISVdegYEAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNelgrvtflPL 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1135 RSACEKEEMNRELAWLKEEG---------VKQNTAVRELQEQLHQQSAQTNSLSQ-----NETKLKAQLEKLEGDLNH-- 1198
Cdd:TIGR02168  579 DSIKGTEIQGNDREILKNIEgflgvakdlVKFDPKLRKALSYLLGGVLVVDDLDNalelaKKLRPGYRIVTLDGDLVRpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1199 ------SLRENTSLQERMVELEMLAEKDKL---KVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEelavQ 1269
Cdd:TIGR02168  659 gvitggSAKTNSSILERRREIEELEEKIEEleeKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK----D 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1270 LEIYSKKTEALLQaktnelinissnKINAILARISHCQNHTTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQAT 1349
Cdd:TIGR02168  735 LARLEAEVEQLEE------------RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1350 RQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISSLSKQL 1429
Cdd:TIGR02168  803 EALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1430 TDLNTQLQnsiSLTEKEAAISSLSKRYEEQQRELLGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEwkkkaqskfiqY 1509
Cdd:TIGR02168  883 ASLEEALA---LLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE-----------E 948

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1510 HSTNKELQMQLELKTKEVSEKAE-QIHSLKENLD--------------QQNERLVCLKGEMEDKKSKLEK 1564
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARrRLKRLENKIKelgpvnlaaieeyeELKERYDFLTAQKEDLTEAKET 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 219-870 8.77e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 8.77e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  219 YQTLQREKKKLQGILsqsqdkALRRIGELREELQMDQQAKKHLQEEfdasLEEKDQHISVLQTQVSLLKQRLrngpmnvd 298
Cdd:COG1196    215 YRELKEELKELEAEL------LLLKLRELEAELEELEAELEELEAE----LEELEAELAELEAELEELRLEL-------- 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  299 lpkpfpqmepqaegvskentdgdiepvvvdgasaktlEVLQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLD 378
Cdd:COG1196    277 -------------------------------------EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  379 ERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQ 458
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  459 KEKsekaafEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAvdvmKKSSEQIVKLQKLH 538
Cdd:COG1196    400 AQL------EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE----EEEEALLELLAELL 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  539 EEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQqesLALEELELQKKAILMESENKLRDLQQEAETY 618
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL---LAGLRGLAGAVAVLIGVEAAYEAALEAALAA 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  619 RT--RILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLW----------TEKLQV 686
Cdd:COG1196    547 ALqnIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREadaryyvlgdTLLGRT 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  687 LKQEHQTEMEKLREKHEQEKETLLKDKESLFQAhiEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQ 766
Cdd:COG1196    627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAG--GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  767 ADKVKQELEAKLDEQKsHHQQQVESIIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKR----- 841
Cdd:COG1196    705 EERELAEAEEERLEEE-LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgpvn 783

                          650       660       670
                   ....*....|....*....|....*....|.
gi 1753147357  842 --SEEELQQASAKLAlFQSQQSTTHEQAKAS 870
Cdd:COG1196    784 llAIEEYEELEERYD-FLSEQREDLEEARET 813
PTZ00121 PTZ00121
MAEBL; Provisional
 1478-2151 1.21e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.02  E-value: 1.21e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1478 SKEKVSALEQVDHLSNKFSEWKKKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMED 1557
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1558 KKsKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAE 1637
Cdd:PTZ00121  1163 AR-KAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1638 EKVSRLEKQVSSMKSELETKKKELEHANSGMKGKE----EELKALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQME 1713
Cdd:PTZ00121  1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEarkaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1714 EKEQQYKKDTEghlgELNTKLQEKEREIQVLEEKlqsvEGPPQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVS 1793
Cdd:PTZ00121  1322 KKAEEAKKKAD----AAKKKAEEAKKAAEAAKAE----AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1794 ALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRYQEllIKIEHAEAKQHEDQIMINHLQKELEEKSKNYSliASQHVEEE 1873
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE--KKKADEAKKKAEEAKKADEAKKKAEEAKKAEE--AKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1874 GGKNNIGAKQNLENVVDDVQKTLQEKELACQILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTE 1953
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD 1549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1954 ALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQ-EMEE 2032
Cdd:PTZ00121  1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAE 1629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2033 KIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAK 2112
Cdd:PTZ00121  1630 EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1753147357 2113 RYEE------ILDAREEEMTAKVMDLQTQLEELQNKYQERLQQEE 2151
Cdd:PTZ00121  1710 KEAEekkkaeELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE 1754
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1519-2141 3.51e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 3.51e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1519 QLELKTKEVSEKAEQIHSLKENLDQQNERLVclkgEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLN 1598
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1599 EALNKYNQQKDTEQKEMLQKLQHIQELGEEKDN---RVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEEL 1675
Cdd:COG1196    295 AELARLEQDIARLEERRRELEERLEELEEELAEleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1676 KALEDRLELESAAKLAELKKKAEQkiaaikKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQSVEgpp 1755
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAEL------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE--- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1756 qseasavprSAEHMAACAEQEEAGLqgcvqkayEDKVSALQRSLMEKEKLLQRLEQEKEEMVSshsemqgryQELLIKIE 1835
Cdd:COG1196    446 ---------EAAEEEAELEEEEEAL--------LELLAELLEEAALLEAALAELLEELAEAAA---------RLLLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1836 HAEAKQHEDQIMINHLQKELEEKSKNYSLIASQHVEEEGGKNNIGAKQNLENVVDDVQKTLQEKELACQILEQKIKELDS 1915
Cdd:COG1196    500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1916 CLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQ 1995
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1996 KLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMtiKETI 2075
Cdd:COG1196    660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE--REEL 737

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 2076 DKAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAKRYEEI-------------LDAREEEMTAKVMDLQTQLEELQN 2141
Cdd:COG1196    738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaieeyeeLEERYDFLSEQREDLEEARETLEE 816
PTZ00121 PTZ00121
MAEBL; Provisional
 439-1177 4.60e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.10  E-value: 4.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  439 AQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQ 518
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  519 EAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKfqTQERQFQEQMKIALEKSQSEYLKitQEKEQQESLALEELELQKK 598
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKAEAARKAEEVRKAEELRKA--EDARKAEAARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKKD 1238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  599 AILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAihlEAEKNKHNKEITIMVEKHKTElESLQHQQDT 678
Cdd:PTZ00121  1239 AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEEA 1314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  679 LWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLEE 758
Cdd:PTZ00121  1315 KKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  759 ELSVLKDQADKVKQELEAKLDEQKSHHQ--QQVESIIKEQEMSIQRTEKELKDEINQLGlLLKEKDKHLKEQQAHVENLE 836
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADEakKKAEEKKKADEAKKKAEEAKKADEAKKKA-EEAKKAEEAKKKAEEAKKAD 1473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  837 ADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKlldleTERILLTEQVAEVETQKKDVCTELDTHKIQV 916
Cdd:PTZ00121  1474 EAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKK-----AEEAKKADEAKKAEEAKKADEAKKAEEKKKA 1548

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  917 RDLLQQLENQKSemEEKLQALTQRYESQLRDTNTEQAQTKQNLIEK--ENVILQMREGQSKEIETLKQKLSAKEDSFSVL 994
Cdd:PTZ00121  1549 DELKKAEELKKA--EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAriEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  995 HEEYEIKFKNQ-EKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANSAGISDAVSR 1073
Cdd:PTZ00121  1627 KAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1074 LETNQKEQIESLTEVHRRELSDVVSVWEkrLNQQAEELQEQHEiQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEE 1153
Cdd:PTZ00121  1707 LKKKEAEEKKKAEELKKAEEENKIKAEE--AKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783

                          730       740
                   ....*....|....*....|....
gi 1753147357 1154 GVKQNTAVRELQEQLHQQSAQTNS 1177
Cdd:PTZ00121  1784 ELDEEDEKRRMEVDKKIKDIFDNF 1807
PTZ00121 PTZ00121
MAEBL; Provisional
 1444-2102 5.72e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 71.71  E-value: 5.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1444 EKEAAISSLSKRYEEQQRELLGQVQDLSLKVETLSK-EKVSALEQVDHLSNKFSEWKKKAQSKF-IQYHSTNKELQMQLE 1521
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKaEEERNNEEIRKFEEARMAHFARRQAAIkAEEARKADELKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1522 LKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEAL 1601
Cdd:PTZ00121  1289 KKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA 1368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1602 NKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKK--ELEHANSGMKGKEEELKALE 1679
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKaeEKKKADEAKKKAEEAKKADE 1448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1680 DRLELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEghlgelntKLQEKEREIQVLEEKLQSVEGPPQSEA 1759
Cdd:PTZ00121  1449 AKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE--------EAKKKADEAKKAAEAKKKADEAKKAEE 1520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1760 SAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEmvsshsEMQGRYQELLIKIEHAEA 1839
Cdd:PTZ00121  1521 AKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK------NMALRKAEEAKKAEEARI 1594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1840 KQHEDQIMINHLQKELEEKSKNYSLIASQHVEEEggknnigakqnlENVVDDVQKTLQEKELACQILEQKIKELDSCLVR 1919
Cdd:PTZ00121  1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA------------EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1920 EREGHRVEMEELtskfEKLQALQQQMEGKNKPTEALEESAEEKSKshvvqprlpgnmeaehndlefklagAEQEKQKLGK 1999
Cdd:PTZ00121  1663 AAEEAKKAEEDK----KKAEEAKKAEEDEKKAAEALKKEAEEAKK-------------------------AEELKKKEAE 1713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2000 EIVKLQKdlrmLRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQ 2079
Cdd:PTZ00121  1714 EKKKAEE----LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEED 1789

                          650       660
                   ....*....|....*....|...
gi 1753147357 2080 DVEAELLESHQEETNQLYKKIAE 2102
Cdd:PTZ00121  1790 EKRRMEVDKKIKDIFDNFANIIE 1812
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1568-2142 1.19e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.35  E-value: 1.19e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1568 NLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEkdnrVKEAEEKVSRLEKQV 1647
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE----LARLEQDIARLEERR 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1648 SSMKSELETKKKELEHANSGMKGKEEELKALEDrlELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKkdteghl 1727
Cdd:COG1196    312 RELEERLEELEEELAELEEELEELEEELEELEE--ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE------- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1728 gELNTKLQEKEREIQVLEEKLQSVEgppQSEASAVPRSAEHMAACAEQEEAglqgcvQKAYEDKVSALQRSLMEKEKLLQ 1807
Cdd:COG1196    383 -ELAEELLEALRAAAELAAQLEELE---EAEEALLERLERLEEELEELEEA------LAELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1808 RLEQEKEEmvsshsemqgryqeLLIKIEHAEAKQHEDQIMINHLQKELEEKSKNYSLIASQHVEEEGGKNNIGAKQNLEN 1887
Cdd:COG1196    453 ELEEEEEA--------------LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1888 vvddvqktLQEKELACQILEQKIKELDSCLVREREGHRVEmeELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHV 1967
Cdd:COG1196    519 --------LRGLAGAVAVLIGVEAAYEAALEAALAAALQN--IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1968 VQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIV-------------KLQKDLRMLRKEHQQELDIMKKEYEQEMEEKI 2034
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLgrtlvaarleaalRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2035 KQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAKRY 2114
Cdd:COG1196    669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580
                   ....*....|....*....|....*...
gi 1753147357 2115 EEILDAREEEMtAKVMDLQTQLEELQNK 2142
Cdd:COG1196    749 EEEALEELPEP-PDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 192-961 3.07e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 3.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  192 EQLIQLLRRMERRLNSYKgKCSEFVIAYQTLQREKKKLQGILSQSQDKALRrigELREELQMDQQAKKHLQEEFDASLEE 271
Cdd:TIGR02168  189 DRLEDILNELERQLKSLE-RQAEKAERYKELKAELRELELALLVLRLEELR---EELEELQEELKEAEEELEELTAELQE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  272 KDQHISVLQTQVSLLKQRLRNGpmnvdlpkpfpQMEPQAEGVSKENTDGDIEPVVVDGASA-KTLEVLQQRVKRQENLLQ 350
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEEL-----------QKELYALANEISRLEQQKQILRERLANLeRQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  351 RCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKElHMAEKTKLITQLRDAKNLIEQLEQdkgmVIAETKRQMHET 430
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELES-RLEELEEQLETLRSKVAQLELQIA----SLNNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  431 LEMKEEEIAQLRSRIKQmtaQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQ 510
Cdd:TIGR02168  409 LERLEDRRERLQQEIEE---LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  511 LELSRVKQEAVDVMKKSSEQI-VKLQKLHEEELASKEQELTKKFQTQErQFQEQMKIALEKSQSEYLKITQEKEQQESLA 589
Cdd:TIGR02168  486 QLQARLDSLERLQENLEGFSEgVKALLKNQSGLSGILGVLSELISVDE-GYEAAIEAALGGRLQAVVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  590 LEELELQKKAILMESENKLRDLQ-------QEAETYRTRILELESSLEK------------------------------- 631
Cdd:TIGR02168  565 LKQNELGRVTFLPLDSIKGTEIQgndreilKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvddldnalelakklrpg 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  632 --------------------------SLQESKNQSEDLAIHLEAEKNKhNKEITIMVEKHKTELESLQHQQDTLWTEKLQ 685
Cdd:TIGR02168  645 yrivtldgdlvrpggvitggsaktnsSILERRREIEELEEKIEELEEK-IAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  686 VLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKD 765
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  766 QADkvkqELEAKLDEQKSHHQQQvesiikeqemsiQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEE 845
Cdd:TIGR02168  804 ALD----ELRAELTLLNEEAANL------------RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  846 LQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLEN 925
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE 947

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1753147357  926 QKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIE 961
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 332-905 4.30e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.81  E-value: 4.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  332 AKTLEVLQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQ---LDERLQELEKMKELHMAEKTKLITQLRDAKNL 408
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELEEE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  409 IEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESwRKMK 488
Cdd:COG1196    325 LAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL-AAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  489 AEVDEQIKAIEKTRE---EERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQ-EQM 564
Cdd:COG1196    403 EELEEAEEALLERLErleEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAlAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  565 KIALEKSQSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLA 644
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  645 IHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEM 724
Cdd:COG1196    563 IEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  725 NEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTE 804
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  805 KELKD-----EINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKL---------ALfqsqqstthEQAKAS 870
Cdd:COG1196    723 EEALEeqleaEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIealgpvnllAI---------EEYEEL 793

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1753147357  871 EEHLAQLQQKLLDLETERILLTEQVAEVETQKKDV 905
Cdd:COG1196    794 EERYDFLSEQREDLEEARETLEEAIEEIDRETRER 828
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 750-1018 5.09e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 5.09e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  750 LKARNKLEEELSVLKDQADKVKQELEAKLDEQkshhqQQVESIIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQ 829
Cdd:COG1196    231 LLKLRELEAELEELEAELEELEAELEELEAEL-----AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  830 AhvenLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTEL 909
Cdd:COG1196    306 R----LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  910 DTHKIQVRDLLQQLENQKSEM---EEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMREGQSKEIETLKQKLSA 986
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLeelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1753147357  987 KEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKE 1018
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARL 493
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 335-888 5.13e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 5.13e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  335 LEVLQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKElhmaektklitQLRDAKNLIEQLEQ 414
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA-----------EEYELLAELARLEQ 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  415 DKgMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEK------AAFEELEKALSTAQKAEESWRKMK 488
Cdd:COG1196    303 DI-ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEeleeaeAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  489 AEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHE-----EELASKEQELTKKFQTQERQfqeq 563
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEleeeeEEEEEALEEAAEEEAELEEE---- 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  564 mKIALEKSQSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDL 643
Cdd:COG1196    458 -EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  644 AIHLEAEknkhnkEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEE 723
Cdd:COG1196    537 EAALEAA------LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  724 MNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQAD-KVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQR 802
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGgSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  803 TEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLL 882
Cdd:COG1196    691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770


                   ....*.
gi 1753147357  883 DLETER 888
Cdd:COG1196    771 RLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1227-2120 6.03e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.16  E-value: 6.03e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1227 LTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQ--AKTNELINISSNKINAILARIS 1304
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEelKEAEEELEELTAELQELEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1305 hcqnhttkvkealviktckasELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQ 1384
Cdd:TIGR02168  271 ---------------------ELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1385 QAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQnsisltekeaaisslskRYEEQQRELL 1464
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE-----------------TLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1465 GQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEWKKKAQSKFIQYHSTN-KELQMQLELKTKEVSEKAEQIHSLKENLDQ 1543
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1544 QNERLVCLKGEMEDKKSKLEKKEcNLETELKTQTARIVELQEHLTQKITEIESLNEALN---KYNQQKDTEQKEMLQKL- 1619
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLE-RLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdeGYEAAIEAALGGRLQAVv 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1620 --------QHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRL-------EL 1684
Cdd:TIGR02168  552 venlnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvdDL 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1685 ESAAKLAElKKKAEQKIAAIKKQLLSQmeeKEQQYKKDTEGHLGelntkLQEKEREIQVLEEKLqsvegppqseasavpr 1764
Cdd:TIGR02168  632 DNALELAK-KLRPGYRIVTLDGDLVRP---GGVITGGSAKTNSS-----ILERRREIEELEEKI---------------- 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1765 saehmaacaeqeeaglqgcvqKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRYQELLIKIEHAEAKQHED 1844
Cdd:TIGR02168  687 ---------------------EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1845 QIMINHLQKELEEKSKNYSLIASQHVEEEggknniGAKQNLENVVDDVQKTLQEKELACQILEQKIKELdsclvreREGH 1924
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAE------EELAEAEAEIEELEAQIEQLKEELKALREALDEL-------RAEL 812

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1925 RVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVvqprlpgNMEAEHNDLEFKLAGAEQEKQKLGKEIVKL 2004
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE-------SLAAEIEELEELIEELESELEALLNERASL 885

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2005 QKDLRMLRKEHQQeldimKKEYEQEMEEKIKQEQEDLELKhnstlkqlmREFHTQLAQKDQELEMTIKETIDKAqdveAE 2084
Cdd:TIGR02168  886 EEALALLRSELEE-----LSEELRELESKRSELRRELEEL---------REKLAQLELRLEGLEVRIDNLQERL----SE 947

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1753147357 2085 LLESHQEETNQLYKKIAEKEDDLQRTAKRYEEILDA 2120
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
PTZ00121 PTZ00121
MAEBL; Provisional
 1479-1925 6.95e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 6.95e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1479 KEKVSALEQVDHLSNKFSEWKKKAQS--KFIQYHSTNKELQMQLELKTK--EVSEKAEQIHSLKENLDQQNERLvclKGE 1554
Cdd:PTZ00121  1384 KKKAEEKKKADEAKKKAEEDKKKADElkKAAAAKKKADEAKKKAEEKKKadEAKKKAEEAKKADEAKKKAEEAK---KAE 1460

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1555 MEDKKSKLEKK--ECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNR 1632
Cdd:PTZ00121  1461 EAKKKAEEAKKadEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAK 1540

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1633 VKEAEEKVSRLEKQVSSMKSE----LETKKKELEHANSGMKGKEEELKALEDRLELESAAKLAELKKKAEQKIAAIKKQL 1708
Cdd:PTZ00121  1541 KAEEKKKADELKKAEELKKAEekkkAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKI 1620

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1709 LSQMEEKEQQYKKDTEghlgelntKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQeeaglqgcVQKAY 1788
Cdd:PTZ00121  1621 KAEELKKAEEEKKKVE--------QLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE--------AKKAE 1684

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1789 EDKVSALQRSLMEKE--KLLQRLEQEKEEMVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELEEKSKnyslia 1866
Cdd:PTZ00121  1685 EDEKKAAEALKKEAEeaKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK------ 1758

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 1867 SQHVEEEGGKNNIGAKQNLENVVDDVQKtlQEKELACQILEQKIKELDSCLVREREGHR 1925
Cdd:PTZ00121  1759 IAHLKKEEEKKAEEIRKEKEAVIEEELD--EEDEKRRMEVDKKIKDIFDNFANIIEGGK 1815
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 422-1019 1.31e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.31e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  422 ETKRQMHETlemkEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAF--EELEKALSTAQKAEESWRKMK-AEVDEQIKAI 498
Cdd:COG1196    176 EAERKLEAT----EENLERLEDILGELERQLEPLERQAEKAERYRElkEELKELEAELLLLKLRELEAElEELEAELEEL 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  499 EKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEyLKI 578
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE-LEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  579 TQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEI 658
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  659 TIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMnektfEKLDVKQTE 738
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE-----AALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  739 LESLSSELSDILKARNKLEEELS-----VLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEINQ 813
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEgvkaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  814 LG----------LLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQ---QSTTHEQAKASEEHLAQLQQK 880
Cdd:COG1196    566 LKaakagratflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTllgRTLVAARLEAALRRAVTLAGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  881 LLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLI 960
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357  961 EKENVILQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEikfknQEKKMEKIKQKAKEM 1019
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE-----LERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1435-2004 1.78e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 1.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1435 QLQNSISLTEKEAAISSLsKRYEEQQRELLGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEWKKK---AQSKFIQYHS 1511
Cdd:COG1196    217 ELKEELKELEAELLLLKL-RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEleeAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1512 TNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKI 1591
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1592 TEIESLNEALNKYnQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGK 1671
Cdd:COG1196    376 EAEEELEELAEEL-LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1672 EEELKALEDRLE--LESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQ 1749
Cdd:COG1196    455 EEEEEALLELLAelLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1750 SVEGPPQSEASA-----VPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRSlmeKEKLLQRLEQEKEEMVSSHSEMQ 1824
Cdd:COG1196    535 AYEAALEAALAAalqniVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAAL---AAALARGAIGAAVDLVASDLREA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1825 GRYQELLIKIEHAEAKQHEDQIMINHLQKELEEKSKnySLIASQHVEEEGGKNNIGAKQNLENVVDDVQKTLQEKELACQ 1904
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR--EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1905 ILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEkskshvvqprLPGNMEAEHNDLE 1984
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE----------LLEEEALEELPEP 759

                          570       580
                   ....*....|....*....|
gi 1753147357 1985 FKLAGAEQEKQKLGKEIVKL 2004
Cdd:COG1196    760 PDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1522-2199 2.16e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 2.16e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1522 LKTKEVSEKAE-QIHSLKENLDQQNERLVCLKGEME--DKKSKLEKKECNLETELKTQTARIveLQEHLTQKITEIESLN 1598
Cdd:TIGR02168  168 SKYKERRKETErKLERTRENLDRLEDILNELERQLKslERQAEKAERYKELKAELRELELAL--LVLRLEELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1599 EALNKYNQQKDTEQKEmlqkLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKAL 1678
Cdd:TIGR02168  246 EELKEAEEELEELTAE----LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1679 EDRLE------LESAAKLAELKKKAEQkiAAIKKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQSVe 1752
Cdd:TIGR02168  322 EAQLEelesklDELAEELAELEEKLEE--LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1753 gppQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRYQELLI 1832
Cdd:TIGR02168  399 ---NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1833 KIEHAEAKQHEDQIMINHLQKELEEKSKNYSLIASQHVEEEGGKNNIGAKQNLENV--------------------VDDV 1892
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVdegyeaaieaalggrlqavvVENL 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1893 QKTLQEKEL-------------ACQILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESA 1959
Cdd:TIGR02168  556 NAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1960 EEKSKSH------------------VVQPRLPGN-------------------MEAEHNDLEFKLAGAEQEKQKLGKEIV 2002
Cdd:TIGR02168  636 ELAKKLRpgyrivtldgdlvrpggvITGGSAKTNssilerrreieeleekieeLEEKIAELEKALAELRKELEELEEELE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2003 KLQKDLRMLRKEH---QQELDIMKKEYEQ--EMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKD--QELEMTIKETI 2075
Cdd:TIGR02168  716 QLRKELEELSRQIsalRKDLARLEAEVEQleERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAeiEELEAQIEQLK 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2076 DKAQDVEAELLESHQEETN-------------QLYKKIAEKEDDLQRTAKRYEEiLDAREEEMTAKVMDLQTQLEELQNK 2142
Cdd:TIGR02168  796 EELKALREALDELRAELTLlneeaanlrerleSLERRIAATERRLEDLEEQIEE-LSEDIESLAAEIEELEELIEELESE 874

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1753147357 2143 YQERLQQEESpgnDKITIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYE 2199
Cdd:TIGR02168  875 LEALLNERAS---LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1444-2127 3.48e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 3.48e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1444 EKEAAISSLsKRYEEQQRELLGQVQDLSLKVETLSKEKVSALEqVDHLSNKFSEWKKKAQSKFIQYHSTNKE-------- 1515
Cdd:TIGR02169  171 KKEKALEEL-EEVEENIERLDLIIDEKRQQLERLRREREKAER-YQALLKEKREYEGYELLKEKEALERQKEaierqlas 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1516 LQMQLELKTKEVSEKAEQIHSLKENLDQQNERL--------VCLKGEMEDKKSKLEKKECNL---ETELKTQTARIVELQ 1584
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgeeeqLRVKEKIGELEAEIASLERSIaekERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1585 EHLTQKITEIESLNEALNKYNQQKD---TEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKEL 1661
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDkltEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1662 EHANSGMKGKEEELKALEDRLElESAAKLAELKKKAEQKIAAIKKQ-----LLSQMEEKEQQYKKDTEGHLGELNTKLQE 1736
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIA-GIEAKINELEEEKEDKALEIKKQewkleQLAADLSKYEQELYDLKEEYDRVEKELSK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1737 KEREIQVLEEKLQSVE--GPPQSEASAVPRS----------------AEHMAACAEQEEAGLQGCVQKAYEDKVSALQrs 1798
Cdd:TIGR02169  488 LQRELAEAEAQARASEerVRGGRAVEEVLKAsiqgvhgtvaqlgsvgERYATAIEVAAGNRLNNVVVEDDAVAKEAIE-- 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1799 LMEKEKL-------LQRLEQEKEEMVSSHSEMQGRYQELLIKIEH-------------------AEAKQHEDQIMINHLQ 1852
Cdd:TIGR02169  566 LLKRRKAgratflpLNKMRDERRDLSILSEDGVIGFAVDLVEFDPkyepafkyvfgdtlvvediEAARRLMGKYRMVTLE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1853 KELEEKS-----------KNYSLIASQHVEEEGGKNNIGAKQNLENV----VDDVQKTLQEKELACQILEQKIKELDSCL 1917
Cdd:TIGR02169  646 GELFEKSgamtggsraprGGILFSRSEPAELQRLRERLEGLKRELSSlqseLRRIENRLDELSQELSDASRKIGEIEKEI 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1918 VREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSkshvvqpRLPGNMEAEHNDLEFKLAGA-----EQ 1992
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELE-------EDLHKLEEALNDLEARLSHSripeiQA 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1993 EKQKLGKEIVKLQKDLRMLRKEHQQELdiMKKEYEQEMEEKIKQEQEDLELKHNSTLKQL------MREFHTQLAQKDQE 2066
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLREIEQKLNRLT--LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIenlngkKEELEEELEELEAA 876

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 2067 LEMTIKETIDKAQDVEAelLESHQEETNQLYKKIAEKEDDLQRTAKRYEEILDAREEEMTA 2127
Cdd:TIGR02169  877 LRDLESRLGDLKKERDE--LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 996-1746 3.69e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 3.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  996 EEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANsAGISDAVSRLE 1075
Cdd:TIGR02169  211 ERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELN-KKIKDLGEEEQ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1076 TNQKEQIESLtEVHRRELSDVVSVWEKRLnQQAEELQEQHEIQLQEKEQEVAELKQKILRSACE-----------KEEMN 1144
Cdd:TIGR02169  290 LRVKEKIGEL-EAEIASLERSIAEKEREL-EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRrdklteeyaelKEELE 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1145 RELAWLKEEGVKQNTAVREL---QEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDK 1221
Cdd:TIGR02169  368 DLRAELEEVDKEFAETRDELkdyREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1222 LKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELA---------VQLEIYSKKTEALLQAKTNELINIS 1292
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAeaeaqarasEERVRGGRAVEEVLKASIQGVHGTV 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1293 SNKINAILARISHCQNHTTKVKEALVIKTckaSELEAQLRQLTEEQNTLNSSFQQATR-QLEEKENQIKSMKADIE---- 1367
Cdd:TIGR02169  528 AQLGSVGERYATAIEVAAGNRLNNVVVED---DAVAKEAIELLKRRKAGRATFLPLNKmRDERRDLSILSEDGVIGfavd 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1368 -------------------GLVMEKEALQREGGNQQqaasekescITQLKKELSENINAVTLMKEELKEKKSEISSLSKQ 1428
Cdd:TIGR02169  605 lvefdpkyepafkyvfgdtLVVEDIEAARRLMGKYR---------MVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAE 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1429 LTDLNTQLQnsiSLTEKEAAISSLSKRYEEQQRELLGQVQDLSLKVETLSKEkvsaleqvdhlsnkfsewkkkaQSKFIQ 1508
Cdd:TIGR02169  676 LQRLRERLE---GLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKE----------------------IEQLEQ 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1509 YHSTNKELQMQLELKTKEVSEKaeqihslKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTAR-IVELQEHL 1587
Cdd:TIGR02169  731 EEEKLKERLEELEEDLSSLEQE-------IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPeIQAELSKL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1588 TQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKK---KELEHA 1664
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEaalRDLESR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1665 NSGMKGK----EEELKALEDRL-ELESAAKLAELKKKAEQKIAAIKKQLLSQMEE--KEQQYKKDTEGHLGELNTKLQEK 1737
Cdd:TIGR02169  884 LGDLKKErdelEAQLRELERKIeELEAQIEKKRKRLSELKAKLEALEEELSEIEDpkGEDEEIPEEELSLEDVQAELQRV 963


                   ....*....
gi 1753147357 1738 EREIQVLEE 1746
Cdd:TIGR02169  964 EEEIRALEP 972
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 999-1670 5.42e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 65.04  E-value: 5.42e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  999 EIKFKNQEKKMEKIKQKAKEMQETLK--KKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANSAGISDAV-SRLE 1075
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKnlDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSkINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1076 TNQKEQIESLTEVHRRELsdvvsvweKRLNQQAEELQEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGV 1155
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKL--------EKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1156 KQNTAVrelqEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERmvelemlAEKDKLKVFELTDKLKTTD 1235
Cdd:TIGR04523  184 NIQKNI----DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDN-------IEKKQQEINEKTTEISNTQ 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1236 AQFQSLQSSHERNEKSLEDKSLEF---KKLSEELAVQLEIYSKKTEALLQAKTNELINISSNKINAILARISHCQNHTTK 1312
Cdd:TIGR04523  253 TQLNQLKDEQNKIKKQLSEKQKELeqnNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQ 332

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1313 VKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKES 1392
Cdd:TIGR04523  333 NNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE 412

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1393 CITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNSISLTEK-EAAISSLSKRYEEQQRELLGQVQDLS 1471
Cdd:TIGR04523  413 QIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESlETQLKVLSRSINKIKQNLEQKQKELK 492

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1472 LKVETLSKEKvsalEQVDHLSNKFSEWKKKaqskfiqyhstNKELQMQLELKTKEVSEKAEQIHSLKENLdqqnerlvcl 1551
Cdd:TIGR04523  493 SKEKELKKLN----EEKKELEEKVKDLTKK-----------ISSLKEKIEKLESEKKEKESKISDLEDEL---------- 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1552 kgemedKKSKLEKKECNLETELKTQTARIVELQehltQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDN 1631
Cdd:TIGR04523  548 ------NKDDFELKKENLEKEIDEKNKEIEELK----QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEK 617

                          650       660       670
                   ....*....|....*....|....*....|....*....
gi 1753147357 1632 RVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKG 1670
Cdd:TIGR04523  618 ELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
PTZ00121 PTZ00121
MAEBL; Provisional
 490-1287 5.68e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.16  E-value: 5.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  490 EVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALE 569
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  570 KSQSEYLKITQEKEQQESLALEelelqKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEA 649
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAKKAEAA-----RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEE 1234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  650 EKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTF 729
Cdd:PTZ00121  1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEA 1314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  730 EKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKD 809
Cdd:PTZ00121  1315 KKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  810 EINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLalfQSQQSTTHEQAKASEEHLAQLQQKLLDLETERI 889
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK---KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  890 LLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRdtNTEQAQTKQNLIEKENVILQM 969
Cdd:PTZ00121  1472 ADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK--KAEEAKKADEAKKAEEKKKAD 1549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  970 REGQSKEIETLKQKLSAKEdsfsvlhEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKE 1049
Cdd:PTZ00121  1550 ELKKAEELKKAEEKKKAEE-------AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1050 KQFNAKILEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELSDVvsvwEKRLNQQAEELQEQHEIQLQEKEQEV--A 1127
Cdd:PTZ00121  1623 EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK----AEEDKKKAEEAKKAEEDEKKAAEALKkeA 1698

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1128 ELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQSAQTNSLSQNETKlKAQLEKLEGDLNHSLRENTSLQ 1207
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEK 1777

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1208 ERMVElEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAKTNE 1287
Cdd:PTZ00121  1778 EAVIE-EELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNK 1856
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1326-1749 1.17e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.91  E-value: 1.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1326 ELEAQLRQLTEEQNTLNSSFQQATRQL----------EEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCIT 1395
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRdeadevleehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1396 QLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQN---SISLTEKEAaisslsKRYEEQQRELLGQVQDLSL 1472
Cdd:PRK02224   290 ELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEEcrvAAQAHNEEA------ESLREDADDLEERAEELRE 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1473 KVETLSKEKVSALEQVDHLSNKFSEWKKKAQskfiqyhstnkELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLK 1552
Cdd:PRK02224   364 EAAELESELEEAREAVEDRREEIEELEEEIE-----------ELRERFGDAPVDLGNAEDFLEELREERDELREREAELE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1553 GEMEDKKSKLEKKECNLET-----------------ELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQK-- 1613
Cdd:PRK02224   433 ATLRTARERVEEAEALLEAgkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRie 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1614 EMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRL-----ELESAA 1688
Cdd:PRK02224   513 RLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLaelkeRIESLE 592

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357 1689 KLAELKKKAEQKIAAIkkqllSQMEEKEQQykkdteghLGELNT----KLQEKEREIQVLEEKLQ 1749
Cdd:PRK02224   593 RIRTLLAAIADAEDEI-----ERLREKREA--------LAELNDerreRLAEKRERKRELEAEFD 644
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
835-1068 3.71e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 61.96  E-value: 3.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  835 LEADIKRSEEELQQASAKLALFQSQQSTTH--EQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTh 912
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEFRQKNGLVDlsEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPE- 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  913 kIQVRDLLQQLENQKSEMEEKLQALTQRYES---QLRDTNTEQAQTKQNLIEKENVILQMREGQSKEIETLKQKLSAKED 989
Cdd:COG3206    259 -LLQSPVIQQLRAQLAELEAELAELSARYTPnhpDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLA 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  990 SfsvlheeyeikfknQEKKMEKIKQKAKEMQEtlkkklLDQEAKLKKELENTVL------ELSQKEKQFNAKILEMAQAN 1063
Cdd:COG3206    338 Q--------------LEARLAELPELEAELRR------LEREVEVARELYESLLqrleeaRLAEALTVGNVRVIDPAVVP 397


                   ....*
gi 1753147357 1064 SAGIS 1068
Cdd:COG3206    398 LKPVS 402
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1606-2197 4.69e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 4.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1606 QQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANsgmkgKEEELKALEDRLELE 1685
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-----LELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1686 SAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQykkdtEGHLGELNTKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRS 1765
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAEL-----EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1766 AEHMAACAEQEEAGLQGcvQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRYQELLIKIEHAEAKQHEDQ 1845
Cdd:COG1196    371 EAELAEAEEELEELAEE--LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1846 IMINHLQKELEEKSKnysLIASQHVEEEGGKNNIGAKQNLENVVDDVQKTLQEKELACQILEQKIKELdsclvrereghr 1925
Cdd:COG1196    449 EEEAELEEEEEALLE---LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA------------ 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1926 vemEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHndLEFKLAGAEQEkqkLGKEIVKLQ 2005
Cdd:COG1196    514 ---LLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY--LKAAKAGRATF---LPLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2006 KDLRMLRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAEL 2085
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2086 LESHQEETNQLYKKIAEKEDDLQRTAKRYEEILDAREEEMTAKVMDLQTQLEELQNKYQERLQQEESPGNDKITIMELQT 2165
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                          570       580       590
                   ....*....|....*....|....*....|...
gi 1753147357 2166 QLAQKTTL-ISDSKLKEQEFREQIHNLEDRLKK 2197
Cdd:COG1196    746 ELLEEEALeELPEPPDLEELERELERLEREIEA 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
375-933 1.32e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.46  E-value: 1.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  375 EQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHEtLEMKEEEIAQLRSRIKQMTAQGEE 454
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSE-LPELREELEKLEKEVKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  455 LREQKEKSEK--AAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQL---------ELSRVKQEAVDV 523
Cdd:PRK03918   240 IEELEKELESleGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLsefyeeyldELREIEKRLSRL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  524 MKKSSEQIVKLQKLheEELASKEQELTKKFQTQERQFQEqmkiaLEKSQSEYLKITQEKEQqeslaleeLELQKKAILME 603
Cdd:PRK03918   320 EEEINGIEERIKEL--EEKEERLEELKKKLKELEKRLEE-----LEERHELYEEAKAKKEE--------LERLKKRLTGL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  604 SENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNK------EITimvEKHKTELESlqhqQD 677
Cdd:PRK03918   385 TPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrELT---EEHRKELLE----EY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  678 TLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKAR-NKL 756
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKlIKL 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  757 EEELSVLKDQADKvKQELE---AKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEINQLG------LLLKEKDKHLKE 827
Cdd:PRK03918   538 KGEIKSLKKELEK-LEELKkklAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEpfyneyLELKDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  828 QQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTheQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKdvct 907
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRRE---- 690

                          570       580
                   ....*....|....*....|....*.
gi 1753147357  908 eldthkiQVRDLLQQLENQKSEMEEK 933
Cdd:PRK03918   691 -------EIKKTLEKLKEELEEREKA 709
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 362-1131 1.47e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.37  E-value: 1.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  362 QCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLiTQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL 441
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKK-KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  442 RSRIKQMTAQGEELREQKEKSEKAafEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLE-LSRVKQEA 520
Cdd:TIGR00618  232 REALQQTQQSHAYLTQKREAQEEQ--LKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKaVTQIEQQA 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  521 VDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQEslaleelelqkkai 600
Cdd:TIGR00618  310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQH-------------- 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  601 lmESENKLRDLQQEAETYrTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLW 680
Cdd:TIGR00618  376 --TLTQHIHTLQQQKTTL-TQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  681 TEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNE-KTFEKLDVKQTELESLSSELSDILKARNKLEEE 759
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLElQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQR 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  760 LSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEK--ELKDEINQLGLLLKEKDKHLKEQQAHVENLEA 837
Cdd:TIGR00618  533 GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCdnRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  838 DIKRSEEELQQASAKLALFQSQQSTTHEQAKAsEEHLAQLQQKLLDLETERILLTEQVAEVEtqkkdvcteldthkiqvr 917
Cdd:TIGR00618  613 EQHALLRKLQPEQDLQDVRLHLQQCSQELALK-LTALHALQLTLTQERVREHALSIRVLPKE------------------ 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  918 dLLQQLENQKSEMEEKLQALTQRYESqlrdtnTEQAQTK-QNLIEKENVILQMREGQSKEIETLKQKLSAKEDSFSVLHE 996
Cdd:TIGR00618  674 -LLASRQLALQKMQSEKEQLTYWKEM------LAQCQTLlRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLK 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  997 EYEIKFKNQEKKMEKIKQKAKEmQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANSAGISDAVSRLET 1076
Cdd:TIGR00618  747 ELMHQARTVLKARTEAHFNNNE-EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET 825

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1077 NQKEQIESLTEVHRR-----ELSDVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVAELKQ 1131
Cdd:TIGR00618  826 LVQEEEQFLSRLEEKsatlgEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1007-1845 1.60e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 60.45  E-value: 1.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1007 KKMEKIKQKAKEMQETL--KKKLLDQEAKLKKELENTVLELSQKEKQfnakiLEMAQANSAGISDAVSRLETNQKEQies 1084
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQItsKEAQLESSREIVKSYENELDPLKNRLKE-----IEHNLSKIMKLDNEIKALKSRKKQM--- 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1085 ltEVHRRELSDVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEgvkqnTAVREL 1164
Cdd:TIGR00606  282 --EKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVE-----QGRLQL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1165 QEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSS 1244
Cdd:TIGR00606  355 QADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1245 HERNEKSLEDKSLEFKKLSEELAV------QLEIYSKKTEALLQAKTNELINISSNKINAILARISHCQNHTTKVKEALV 1318
Cdd:TIGR00606  435 KKGLGRTIELKKEILEKKQEELKFvikelqQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1319 IKTCKASELEAQLRQLTEEQNTLNSsfqqATRQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCITQLK 1398
Cdd:TIGR00606  515 RKLRKLDQEMEQLNHHTTTRTQMEM----LTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTR 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1399 KELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNSISLTEKEAAISSLSKRYEEQQRE---LLGQVQDLSLKVE 1475
Cdd:TIGR00606  591 DRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQramLAGATAVYSQFIT 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1476 TLSKEKVSAL---EQVDHLSNKFSEWKKKAQSKFIQYHSTNKELQMQLELKTKEVSE-------KAEQIHSLKENLDQQN 1545
Cdd:TIGR00606  671 QLTDENQSCCpvcQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEmlglapgRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1546 ERLVCLKGEMEDKKSKLEKKECNLET---------ELKTQTARIVELQEHLTQKITEIESLN------------EALNKY 1604
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTimpeeesakVCLTDVTIMERFQMELKDVERKIAQQAaklqgsdldrtvQQVNQE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1605 NQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLE----------KQVSSMKSELETKKKELEHANSGMKGKEEE 1674
Cdd:TIGR00606  831 KQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKseklqigtnlQRRQQFEEQLVELSTEVQSLIREIKDAKEQ 910

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1675 LKALEDRLE------LESAAKLAELKKKAEQKIAAIKKQ----------LLSQMEEKEQQYKKDTEGHLGELNTKLQEKE 1738
Cdd:TIGR00606  911 DSPLETFLEkdqqekEELISSKETSNKKAQDKVNDIKEKvknihgymkdIENKIQDGKDDYLKQKETELNTVNAQLEECE 990

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1739 REIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKllQRLEQEKEEMVS 1818
Cdd:TIGR00606  991 KHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEH--QKLEENIDLIKR 1068

                          890       900
                   ....*....|....*....|....*..
gi 1753147357 1819 SHSEMQGRYQELLIKIEHAEAKQHEDQ 1845
Cdd:TIGR00606 1069 NHVLALGRQKGYEKEIKHFKKELREPQ 1095
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1582-2145 2.28e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.69  E-value: 2.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1582 ELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELgEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKEL 1661
Cdd:PRK03918   169 EVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEI-SSELPELREELEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1662 EHANSGMKGKEEELKALEDRLElESAAKLAELKKKAEQkiaaikkqlLSQMEEKEQQYKKdTEGHLGELNTKLQEKEREI 1741
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIE-ELKKEIEELEEKVKE---------LKELKEKAEEYIK-LSEFYEEYLDELREIEKRL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1742 QVLEEKLQSVEGPPQSEASAVPRSAEhmaACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLE-QEKEEMVSSH 1820
Cdd:PRK03918   317 SRLEEEINGIEERIKELEEKEERLEE---LKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTgLTPEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1821 SEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELEE--KSKNYSLIASQHVEEEgGKNNIGAKQNLEnvVDDVQKTLQE 1898
Cdd:PRK03918   394 EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElkKAKGKCPVCGRELTEE-HRKELLEEYTAE--LKRIEKELKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1899 KELACQILEQKIKELDSCLVREREGHRV-----EMEELTSKFEKLQAlqQQMEGKNKPTEAL-EESAEEKSKSHVVQPRL 1972
Cdd:PRK03918   471 IEEKERKLRKELRELEKVLKKESELIKLkelaeQLKELEEKLKKYNL--EELEKKAEEYEKLkEKLIKLKGEIKSLKKEL 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1973 pgnmeAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKhnSTLKQL 2052
Cdd:PRK03918   549 -----EKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELE--REEKEL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2053 MREfHTQLAQKDQELEMTIKETIDKAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAKRYEEiLDAREEEMTAKVMDL 2132
Cdd:PRK03918   622 KKL-EEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEE-LEKRREEIKKTLEKL 699

                          570
                   ....*....|...
gi 1753147357 2133 QTQLEELQNKYQE 2145
Cdd:PRK03918   700 KEELEEREKAKKE 712
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 663-1462 4.24e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.83  E-value: 4.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  663 EKHKTELESLQHQQDTLWTEKLQVLKQEhqtEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESL 742
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLK---EQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  743 SSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSI---------QRTEKELKDEINQ 813
Cdd:pfam02463  253 IESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVddeeklkesEKEKKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  814 LGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTE 893
Cdd:pfam02463  333 EKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  894 QVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALT-----QRYESQLRDTNTEQAQTKQNLIEKENVILQ 968
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQElkllkDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  969 MREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEK-KMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQ 1047
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLgDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1048 KEKQFNAKILEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVA 1127
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1128 ELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQsaQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQ 1207
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR--RQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1208 ERMVELEMLAEKDKLKVFELTDKLKTTD--------AQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEA 1279
Cdd:pfam02463  731 QDKINEELKLLKQKIDEEEEEEEKSRLKkeekeeekSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1280 LLQAKTNELINISSNKINAILARISHCQNHTTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQI 1359
Cdd:pfam02463  811 KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELES 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1360 KSMKADIEGLvmEKEALQREGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNS 1439
Cdd:pfam02463  891 KEEKEKEEKK--ELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLA 968

                          810       820
                   ....*....|....*....|...
gi 1753147357 1440 ISLTEKEAAISSLSKRYEEQQRE 1462
Cdd:pfam02463  969 KEELGKVNLMAIEEFEEKEERYN 991
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 601-1260 4.56e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 58.70  E-value: 4.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  601 LMESENKLRDLQQEAETYRTRILELeSSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQqdtLW 680
Cdd:pfam12128  236 IMKIRPEFTKLQQEFNTLESAELRL-SHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGE---LS 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  681 TEKLQVLKQEHQTEM--EKLREKHEQEKETLLKDKESL--FQAHIEEMNEK----TFEKLDVKQTELESLSSELSDILKA 752
Cdd:pfam12128  312 AADAAVAKDRSELEAleDQHGAFLDADIETAAADQEQLpsWQSELENLEERlkalTGKHQDVTAKYNRRRSKIKEQNNRD 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  753 RNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEqemsIQRTEKELKDEINQLGLLLKEK--DKHLKEQQa 830
Cdd:pfam12128  392 IAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQAtaTPELLLQL- 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  831 hvENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQV------------AEV 898
Cdd:pfam12128  467 --ENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqagtllhflrKEA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  899 ETQKKDVCTELDTHKIQVRDL---------------------LQQLE-NQKSEMEEKLQALTQRYESQLRDTNTEQAQTK 956
Cdd:pfam12128  545 PDWEQSIGKVISPELLHRTDLdpevwdgsvggelnlygvkldLKRIDvPEWAASEEELRERLDKAEEALQSAREKQAAAE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  957 QNLIEKENVILQMREGQSKEIETLKQklsAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQ--ETLKKKLLDQEAKL 1034
Cdd:pfam12128  625 EQLVQANGELEKASREETFARTALKN---ARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNslEAQLKQLDKKHQAW 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1035 KKELENTVLELSQKEKQFNAKILEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELSDvvsvwekrlnqqaeelQEQ 1114
Cdd:pfam12128  702 LEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLAS----------------LGV 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1115 HEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQN-----------TAVRELQEQLHQQSAQTNSLSQNET 1183
Cdd:pfam12128  766 DPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRprlatqlsnieRAISELQQQLARLIADTKLRRAKLE 845

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1753147357 1184 KLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDklkvfELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFK 1260
Cdd:pfam12128  846 MERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSE-----QAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFK 917
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1081-1857 5.18e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 5.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1081 QIESLTEVHRRELSDV---VSVWEKRLNQQAEELqEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKE----E 1153
Cdd:TIGR02169  146 DFISMSPVERRKIIDEiagVAEFDRKKEKALEEL-EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEkreyE 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1154 GVKQNTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEgdlnhslrentslqERMVELEMLAEKDKLKVFELT-DKLK 1232
Cdd:TIGR02169  225 GYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELE--------------KRLEEIEQLLEELNKKIKDLGeEEQL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1233 TTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEElavqleiyskkteallQAKTNELINISSNKINAILARISHCQNHTTK 1312
Cdd:TIGR02169  291 RVKEKIGELEAEIASLERSIAEKERELEDAEER----------------LAKLEAEIDKLLAEIEELEREIEEERKRRDK 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1313 VKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKES 1392
Cdd:TIGR02169  355 LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1393 CITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLN----------TQLQNSISLTEKEAAISSLSKRYEEQQRE 1462
Cdd:TIGR02169  435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKeeydrvekelSKLQRELAEAEAQARASEERVRGGRAVEE 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1463 LL--------GQVQDLsLKVEtlsKEKVSALE------------QVDHLSNKFSEWKKKAQSKFIQYHSTNKELQMQLEL 1522
Cdd:TIGR02169  515 VLkasiqgvhGTVAQL-GSVG---ERYATAIEvaagnrlnnvvvEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDL 590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1523 KTK-------------EVSEKAEQIHS-------LKENLDQQNE-----RLVCLKGEMEDKKSKL---EKKECNLETELK 1574
Cdd:TIGR02169  591 SILsedgvigfavdlvEFDPKYEPAFKyvfgdtlVVEDIEAARRlmgkyRMVTLEGELFEKSGAMtggSRAPRGGILFSR 670

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1575 TQTARIVELQEhltqkitEIESLnealnkynqqkDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSEL 1654
Cdd:TIGR02169  671 SEPAELQRLRE-------RLEGL-----------KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE 732

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1655 ETKKKELEHANSGMKGKEEELKALEDRLElESAAKLAELkkkaEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGELNTKL 1734
Cdd:TIGR02169  733 EKLKERLEELEEDLSSLEQEIENVKSELK-ELEARIEEL----EEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEV 807

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1735 QEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQ------EEAGLQGCVQKaYEDKVSALQRSLMEKEKLLQR 1808
Cdd:TIGR02169  808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQiksiekEIENLNGKKEE-LEEELEELEAALRDLESRLGD 886

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1753147357 1809 LEQEKEEMVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELEE 1857
Cdd:TIGR02169  887 LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2227-2270 5.30e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.07  E-value: 5.30e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1753147357  2227 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2270
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1458-2145 5.36e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 5.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1458 EQQRELLGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEWK----KKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQ 1533
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQallkEKREYEGYELLKEKEALERQKEAIERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1534 IHSLKENLDQQNERLVCLK-------------------------GEMEDKKSKLEKKECNLETELKTQTARIVELQEHLT 1588
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEqlleelnkkikdlgeeeqlrvkekiGELEAEIASLERSIAEKERELEDAEERLAKLEAEID 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1589 QKITEIESLNEALNKYNQQKD---TEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHAN 1665
Cdd:TIGR02169  333 KLLAEIEELEREIEEERKRRDkltEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1666 SGMKGKEEELKALEDRLElESAAKLAELKKKAEQKIAAIKKQ-----LLSQMEEKEQQYKKDTEGHLGELNTKLQEKERE 1740
Cdd:TIGR02169  413 EELQRLSEELADLNAAIA-GIEAKINELEEEKEDKALEIKKQewkleQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1741 IQVLEEKLQSVE--GPPQSEASAVPRS----------------AEHMAACAEQEEAGLQGCVQKAYEDKVSALQrsLMEK 1802
Cdd:TIGR02169  492 LAEAEAQARASEerVRGGRAVEEVLKAsiqgvhgtvaqlgsvgERYATAIEVAAGNRLNNVVVEDDAVAKEAIE--LLKR 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1803 EKL-------LQRLEQEKEEMVSSHSEMQGRYQELLIKIEH-------------------AEAKQHEDQIMINHLQKELE 1856
Cdd:TIGR02169  570 RKAgratflpLNKMRDERRDLSILSEDGVIGFAVDLVEFDPkyepafkyvfgdtlvvediEAARRLMGKYRMVTLEGELF 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1857 EKSknySLIASQHVEEEGGknnIGAKQNLENVVDDVQKTLQEKELACQILEQKIKELDSclvrEREGHRVEMEELTSKFE 1936
Cdd:TIGR02169  650 EKS---GAMTGGSRAPRGG---ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN----RLDELSQELSDASRKIG 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1937 KLQALQQQMEGK-NKPTEALEESAEEKSKshvvqprlpgnmeaehndLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKeh 2015
Cdd:TIGR02169  720 EIEKEIEQLEQEeEKLKERLEELEEDLSS------------------LEQEIENVKSELKELEARIEELEEDLHKLEE-- 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2016 qqELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLmREFHTQLAQKDQELEMTIKETIDKAQDVEA--ELLESHQEET 2093
Cdd:TIGR02169  780 --ALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDlkEQIKSIEKEI 856

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1753147357 2094 NQLYKKIAEKEDDLQRTAKRYEEiLDAREEEMTAKVMDLQTQLEELQNKYQE 2145
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALRD-LESRLGDLKKERDELEAQLRELERKIEE 907
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1128-2200 8.38e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 58.14  E-value: 8.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1128 ELKQKIlRSACEKEEMNRELAWLKEEGVKQNTAVRELQE-QLHQQSAQTNSLSQNETKLKAQLEKL-EGDLNHSLRENTS 1205
Cdd:TIGR01612  604 ELKEKI-KNISDKNEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSKIyEDDIDALYNELSS 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1206 L-QERMVElemlAEKDKLKVFELTDKLKTTDAQFQSLQ--------SSHERNEKSLEDKSLEFKK-----LSEELAVQLE 1271
Cdd:TIGR01612  683 IvKENAID----NTEDKAKLDDLKSKIDKEYDKIQNMEtatvelhlSNIENKKNELLDIIVEIKKhihgeINKDLNKILE 758

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1272 IYSKKtEALLQAKTNELINiSSNKINAILARISHCQNHttkVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQ 1351
Cdd:TIGR01612  759 DFKNK-EKELSNKINDYAK-EKDELNKYKSKISEIKNH---YNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKI 833

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1352 LeekeNQIKSMKADIEGLVmeKEALQREGGNQQQAASEKES---CITQLKKELS-ENINAVTLMKEELKEKKSEIS-SLS 1426
Cdd:TIGR01612  834 I----NEMKFMKDDFLNKV--DKFINFENNCKEKIDSEHEQfaeLTNKIKAEISdDKLNDYEKKFNDSKSLINEINkSIE 907

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1427 KQLTDLNTQLQNSISLTEKEAAISSLSKRYEEQQRELLGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEWKKK-AQSK 1505
Cdd:TIGR01612  908 EEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAfKDAS 987

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1506 FIQYHSTNKELqmqlelkTKEVSEKAEQIHSLKEN-LDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQ 1584
Cdd:TIGR01612  988 LNDYEAKNNEL-------IKYFNDLKANLGKNKENmLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEI 1060

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1585 EHLTQKitEIESLNEALNKYNQQKDTEQKEMLQKLQH--IQELGEEKD----NRVKEAEEKVSRLEKQVSSMKSELETKK 1658
Cdd:TIGR01612 1061 EKEIGK--NIELLNKEILEEAEINITNFNEIKEKLKHynFDDFGKEENikyaDEINKIKDDIKNLDQKIDHHIKALEEIK 1138

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1659 KELEHANSGMKGKEEELKALEDRLELESAAKlaELKKKAEQKIAAIKKqllsqmeekeqqyKKDTEGHLGELNTKLQEKE 1738
Cdd:TIGR01612 1139 KKSENYIDEIKAQINDLEDVADKAISNDDPE--EIEKKIENIVTKIDK-------------KKNIYDEIKKLLNEIAEIE 1203

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1739 REIQVLEEKL-------QSVEGPPQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLEQ 1811
Cdd:TIGR01612 1204 KDKTSLEEVKginlsygKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISH 1283

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1812 EKEE----MVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELEEKSKNYSLIaSQHVEEEGGKNNIGAKQNLEN 1887
Cdd:TIGR01612 1284 DDDKdhhiISKKHDENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDI-NLYLNEIANIYNILKLNKIKK 1362

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1888 VVDDVQKTLQEKELACQILEQKIKELDSCLVREREGhrVEMEELTSKFEklqalqQQMEGKNKpTEALEESAEekSKSHV 1967
Cdd:TIGR01612 1363 IIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDD--INLEECKSKIE------STLDDKDI-DECIKKIKE--LKNHI 1431

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1968 VQprlpgnmEAEHNDLEFKLAGAEQEKQKL-----------GKEIVKLQKDlrMLRKEHQQELDIMKKEYEQEMEEKIKQ 2036
Cdd:TIGR01612 1432 LS-------EESNIDTYFKNADENNENVLLlfkniemadnkSQHILKIKKD--NATNDHDFNINELKEHIDKSKGCKDEA 1502

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2037 EQEDLELKHNSTLKQLMREFHTQLAQKDQELEmtIKETIDKAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAKRYEE 2116
Cdd:TIGR01612 1503 DKNAKAIEKNKELFEQYKKDVTELLNKYSALA--IKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFR 1580

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2117 ILD--AREEEMTAKVMDLQTQLEELQNKYQeRLQQEESPGNDKITIME-LQTQLAQKTTLISDSKLKE--------QEFR 2185
Cdd:TIGR01612 1581 IEDdaAKNDKSNKAAIDIQLSLENFENKFL-KISDIKKKINDCLKETEsIEKKISSFSIDSQDTELKEngdnlnslQEFL 1659

                         1130
                   ....*....|....*....
gi 1753147357 2186 E----QIHNLEDRLKKYEK 2200
Cdd:TIGR01612 1660 EslkdQKKNIEDKKKELDE 1678
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 960-1749 1.46e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 57.29  E-value: 1.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  960 IEKENVILQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEmqETLKKKLLDQEAKLKKELE 1039
Cdd:pfam02463  130 ISPEAYNFLVQGGKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAEL--IIDLEELKLQELKLKEQAK 207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1040 NTVLELSQKEKQFNAKILEmaqansagisdAVSRLETNQKEQIESLTEVHRRELSDVVSvwEKRLNQQAEELQEQHEIQL 1119
Cdd:pfam02463  208 KALEYYQLKEKLELEEEYL-----------LYLDYLKLNEERIDLLQELLRDEQEEIES--SKQEIEKEEEKLAQVLKEN 274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1120 QEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHS 1199
Cdd:pfam02463  275 KEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAE 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1200 LRENTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEA 1279
Cdd:pfam02463  355 EEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEE 434

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1280 LLQAKTNELINISSNKINAILARishcqnhTTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATR--QLEEKEN 1357
Cdd:pfam02463  435 EEESIELKQGKLTEEKEELEKQE-------LKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERsqKESKARS 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1358 QIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQ 1437
Cdd:pfam02463  508 GLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKL 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1438 NSISLTEKEAAISSLSKRYEEQQRELLGQVQDLSLKV-ETLSKEKVSALEQVDHLSNKFSEWKKKAQSKFIQYHSTNKEL 1516
Cdd:pfam02463  588 KLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVvEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKAS 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1517 QMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIES 1596
Cdd:pfam02463  668 LSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDE 747

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1597 LNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKvsRLEKQVSSMKSELETKKKELEHANSGMKGKEEELK 1676
Cdd:pfam02463  748 EEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEE--EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIE 825

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1753147357 1677 ALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQ 1749
Cdd:pfam02463  826 QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEE 898
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1586-2202 2.23e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 2.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1586 HLTQKITEIESLNEALNKYNQQKdteQKEMLQKLQ-HIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHA 1664
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNK---IELLLQQHQdRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQ 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1665 NSGMKGKEEELKALEDRLELEsaakLAELKKKAEQKIAAIKKQLLSQMEEkeqqykkdteghLGELNTKLQEKEREIQVL 1744
Cdd:pfam15921  312 NSMYMRQLSDLESTVSQLRSE----LREAKRMYEDKIEELEKQLVLANSE------------LTEARTERDQFSQESGNL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1745 EEKLQSVEGPPQSEASAVPRSAEHMAACAEQEEAGlqgcvqkayEDKVSALQRSLMEKEKLLQRLEQEKEEMvssHSEMQ 1824
Cdd:pfam15921  376 DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGN---------SITIDHLRRELDDRNMEVQRLEALLKAM---KSECQ 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1825 GRYQELLIKIEhaeaKQHEDQIMINHLQKELEEKSKnyslIASQHVEEEGGKNNigAKQNLENVVDDVQKTLQEKELACQ 1904
Cdd:pfam15921  444 GQMERQMAAIQ----GKNESLEKVSSLTAQLESTKE----MLRKVVEELTAKKM--TLESSERTVSDLTASLQEKERAIE 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1905 ILEQKIKELDSCL---VREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHN 1981
Cdd:pfam15921  514 ATNAEITKLRSRVdlkLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKA 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1982 DLEFKLAGAEQEKQKLgkEIVKLQKDLRMLRKEHQ-QELDIMKKEYEQEMEEK------IKQEQEDL--ELKHN-STLKQ 2051
Cdd:pfam15921  594 QLEKEINDRRLELQEF--KILKDKKDAKIRELEARvSDLELEKVKLVNAGSERlravkdIKQERDQLlnEVKTSrNELNS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2052 LMREFHT---QLAQKDQELEMTIKETIDKAQDVEAELleshqEETNQLYKKIAEKEDDLQRTAKryeeildAREEEMTAK 2128
Cdd:pfam15921  672 LSEDYEVlkrNFRNKSEEMETTTNKLKMQLKSAQSEL-----EQTRNTLKSMEGSDGHAMKVAM-------GMQKQITAK 739

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1753147357 2129 vmdlQTQLEELQNKYQERLQQEESPGNDKITIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNV 2202
Cdd:pfam15921  740 ----RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1305-1861 2.51e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 56.39  E-value: 2.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1305 HCQNHTTKVKEALVIKTCKASELEAQLRQLTEEqntLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQ 1384
Cdd:pfam12128  266 GYKSDETLIASRQEERQETSAELNQLLRTLDDQ---WKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETA 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1385 QAASEKESCITQLKKELSENINAVT-----LMKEELKEKKSEISSLSKQLTDLNTQLQNSISLTEKEAAI---------S 1450
Cdd:pfam12128  343 AADQEQLPSWQSELENLEERLKALTgkhqdVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVaeddlqaleS 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1451 SLSKRYEEQQRELLGQVQDLSLKVETLSKEKVSALEQVDHLSNK--FSEWKKKAQSKfiQYHSTNKELQMQLEL-KTKEV 1527
Cdd:pfam12128  423 ELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLenFDERIERAREE--QEAANAEVERLQSELrQARKR 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1528 SEKAEqihslkENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTAR--------IVELQEHLTQKITEI--ESL 1597
Cdd:pfam12128  501 RDQAS------EALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDweqsigkvISPELLHRTDLDPEVwdGSV 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1598 NEALNKYNQQKDTEQKEMLQKLQHIQELGEEKD---NRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEE 1674
Cdd:pfam12128  575 GGELNLYGVKLDLKRIDVPEWAASEEELRERLDkaeEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLD 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1675 LKALEDRLELESAAK---LAELKKKAEQKIAAIKKQlLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREiqVLEEKLQSV 1751
Cdd:pfam12128  655 LRRLFDEKQSEKDKKnkaLAERKDSANERLNSLEAQ-LKQLDKKHQAWLEEQKEQKREARTEKQAYWQV--VEGALDAQL 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1752 EGPPQSEASAVPRSAEHMAACAEQEEAGLQGcvQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRY---- 1827
Cdd:pfam12128  732 ALLKAAIAARRSGAKAELKALETWYKRDLAS--LGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWlqrr 809

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1753147357 1828 QELLIKIEHAEAKQHEDQIMINHLQKELEEKSKN 1861
Cdd:pfam12128  810 PRLATQLSNIERAISELQQQLARLIADTKLRRAK 843
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 751-943 2.65e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 2.65e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  751 KARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQ--QVESIIKEQEMSIQRTEKELK---DEINQLGLLLKEKDKHL 825
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQlaALERRIAALARRIRALEQELAaleAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  826 KEQQAHVENLEADIKR-----------SEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQ 894
Cdd:COG4942    100 EAQKEELAELLRALYRlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1753147357  895 VAEVETQKKdvctELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYES 943
Cdd:COG4942    180 LAELEEERA----ALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1313-2145 3.12e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.23  E-value: 3.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1313 VKEALVIKTCKASELEAQLRQLTEEQNTLnssfqqatrqleEKENQIKSMKADIEG--LVMEKEALQREGGNQQQAASEK 1390
Cdd:TIGR02169  182 VEENIERLDLIIDEKRQQLERLRREREKA------------ERYQALLKEKREYEGyeLLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1391 ESCITQLKKELSENinavtlmKEELKEKKSEISSLSKQLTDLNTQLQNSIslTEKEAAISSLSKRYEEQQRELLGQVQDL 1470
Cdd:TIGR02169  250 EEELEKLTEEISEL-------EKRLEEIEQLLEELNKKIKDLGEEEQLRV--KEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1471 SLKVETLSKEKVSALEQVDHLSNKFSEWKKKAqskfIQYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVC 1550
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRR----DKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1551 LKGEMEDkkskLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALnkynQQKDTEQKEMLQKLQHIQELGEEKD 1630
Cdd:TIGR02169  397 LKREINE----LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEK----EDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1631 NRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLElESAAKLAELKKKAEQKIAAIKKQLLS 1710
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQ-GVHGTVAQLGSVGERYATAIEVAAGN 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1711 QME----------EKEQQYKKDTEGhlGELN----TKLQEKEREIQVLEEK------LQSVEGPPQSEA----------- 1759
Cdd:TIGR02169  548 RLNnvvveddavaKEAIELLKRRKA--GRATflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPafkyvfgdtlv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1760 -----SAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLEQEKeemvsshsEMQGRYQELLIKI 1834
Cdd:TIGR02169  626 vedieAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLE--------GLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1835 EHAEAKQHEDQIMINHLQKELEEKSKNYSLIASQHVEEEGGKNNIGAKQ--------NLENVVDDVQKTLQEKELACQIL 1906
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLssleqeieNVKSELKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1907 EQKIKELDSCLVRER-EGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLpgnMEAEHNDLEF 1985
Cdd:TIGR02169  778 EEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRID---LKEQIKSIEK 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1986 KLAGAEQEKQKLGKEIVKLQKDLRMLRKEH---QQELDIMKKEYEqEMEEKIKQEQEDLELKhnstlKQLMREFHTQLAQ 2062
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLESRLgdlKKERDELEAQLR-ELERKIEELEAQIEKK-----RKRLSELKAKLEA 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2063 KDQELEMTIKETIDKAQDVEAEL-LESHQEETNQLYKKIAEKEDDLQRTAKRYEEILDAREE--EMTAKVMDLQTQLEEL 2139
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEELsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDElkEKRAKLEEERKAILER 1008


                   ....*.
gi 1753147357 2140 QNKYQE 2145
Cdd:TIGR02169 1009 IEEYEK 1014
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 334-1058 3.89e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 3.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  334 TLEVLQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRD--AKNLIEQ 411
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEEllAKKKLES 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  412 LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEV 491
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  492 DEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKS 571
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  572 QSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEK 651
Cdd:pfam02463  544 AISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAK 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  652 NKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEK 731
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  732 LDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQqveSIIKEQEMSIQRTEKELKDEI 811
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK---EEKEEEKSELSLKEKELAEER 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  812 NQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILL 891
Cdd:pfam02463  781 EKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  892 TEQVAEVETQkkdvctELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMRE 971
Cdd:pfam02463  861 EEITKEELLQ------ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE 934

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  972 GQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQ 1051
Cdd:pfam02463  935 EEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014


                   ....*..
gi 1753147357 1052 FNAKILE 1058
Cdd:pfam02463 1015 TCQRLKE 1021
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 828-1062 4.04e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 4.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  828 QQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDvct 907
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE--- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  908 eldthkiqvrdLLQQLENQKSEMEEKLQALtQRYESQLRDTNTEQAQTKQNLIEKENVILQMREGQSKEIETLKQKLSAK 987
Cdd:COG4942     95 -----------LRAELEAQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357  988 EDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQEtlKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQA 1062
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAE--RQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 225-1062 4.06e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 4.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  225 EKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQHISVLQTQVSLLKQRLRNGPMNVDLPKPFP 304
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  305 QMEPQAEGVSKEntdgdiepvvvdgasaktlevLQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQEL 384
Cdd:pfam02463  254 ESSKQEIEKEEE---------------------KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  385 EKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSE- 463
Cdd:pfam02463  313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKl 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  464 ----KAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKL-H 538
Cdd:pfam02463  393 keeeLELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSeD 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  539 EEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETY 618
Cdd:pfam02463  473 LLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  619 RTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKL 698
Cdd:pfam02463  553 VSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDT 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  699 REKHEQEKEtllKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKL 778
Cdd:pfam02463  633 ELTKLKESA---KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  779 DEQKSHHQQQVESIIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQS 858
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  859 QQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALT 938
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  939 QRYESQLRDT-------NTEQAQTKQNLIEKENVILQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEK 1011
Cdd:pfam02463  870 QELLLKEEELeeqklkdELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 1012 IKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQA 1062
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERL 1000
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 422-1233 4.20e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 4.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  422 ETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKaaFEELEKALSTAQKAEESWRKMKAEvdEQIKAIEK- 500
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYELLKEKEALE--RQKEAIERq 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  501 --TREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELAskeqeltkkfQTQERQFQEQMKIALEKSQSEYLKI 578
Cdd:TIGR02169  246 laSLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQL----------RVKEKIGELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  579 TQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKei 658
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK-- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  659 timVEKHKTELESLQHQQDTLWTEKLQVLKQ--EHQTEMEKLREKHEQEKETLLKDKESLFQAhiEEMNEKTFEKLDVKQ 736
Cdd:TIGR02169  394 ---LEKLKREINELKRELDRLQEELQRLSEElaDLNAAIAGIEAKINELEEEKEDKALEIKKQ--EWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  737 TELESLSSELSDILKARNKLEEELSVLKDQADKVKQE--------------------LEAKLDEQKSHHQQQVES----- 791
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERvrggraveevlkasiqgvhgTVAQLGSVGERYATAIEVaagnr 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  792 ---IIKEQEMSIQRTEKELKDEinQLG----LLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTH 864
Cdd:TIGR02169  549 lnnVVVEDDAVAKEAIELLKRR--KAGratfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVV 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  865 EQAKASEEHLAQLQQKLLDLE-------------TERILLTEQVAEVEtQKKDVCTELDTHKIQVRDLLQQLENQKSEME 931
Cdd:TIGR02169  627 EDIEAARRLMGKYRMVTLEGElfeksgamtggsrAPRGGILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  932 EKLQALtqryesqlrdtntEQAQTKQNLIEKENVILQmregqsKEIETLKQKLSAKEDSFSVLHEEYEikfkNQEKKMEK 1011
Cdd:TIGR02169  706 ELSQEL-------------SDASRKIGEIEKEIEQLE------QEEEKLKERLEELEEDLSSLEQEIE----NVKSELKE 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1012 IKQKAKEMQETLKKkLLDQEAKLKKELENTVLELSQKEKQfnaKILEMAQANSAGISDAVSRLetNQKEQIESLTEVHRR 1091
Cdd:TIGR02169  763 LEARIEELEEDLHK-LEEALNDLEARLSHSRIPEIQAELS---KLEEEVSRIEARLREIEQKL--NRLTLEKEYLEKEIQ 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1092 ELSDVVSVWEkrlNQQAEELQEQHEIQLQekeqeVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQ 1171
Cdd:TIGR02169  837 ELQEQRIDLK---EQIKSIEKEIENLNGK-----KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL 908

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1753147357 1172 SAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQErMVELEMLAEKDKLKVFELTDKLKT 1233
Cdd:TIGR02169  909 EAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRA 969
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1246-1810 5.52e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.33  E-value: 5.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1246 ERNEKSLE---DKSLEFKKLSEELAV-QLEIYSKKTEALL--QAKTNELINISSNKINAILARISHCQNHTTKVKEALVI 1319
Cdd:COG1196    199 ERQLEPLErqaEKAERYRELKEELKElEAELLLLKLRELEaeLEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1320 KTCKASELEAQLRQLTEEQNTLNSSF-------QQATRQLEEKENQIKSMKADIEGLVMEKEALQREggnQQQAASEKES 1392
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIarleerrRELEERLEELEEELAELEEELEELEEELEELEEE---LEEAEEELEE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1393 CITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNSISLTEKEAAISSLSKRYEEQQRELLGQVQDLSL 1472
Cdd:COG1196    356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1473 KVETLSKEKVSALEQVDHLSNKfsewkKKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLK 1552
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEE-----EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1553 GEMEDKKSKLEKKEC---NLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQK-----------DTEQKEMLQK 1618
Cdd:COG1196    511 KAALLLAGLRGLAGAvavLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratflpldKIRARAALAA 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1619 LQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLELESAAKLAELKKKAE 1698
Cdd:COG1196    591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1699 QKIAAIKKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQSVEGppQSEASAVPRSAEHMAACAEQEEA 1778
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA--LEEQLEAEREELLEELLEEEELL 748

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1753147357 1779 GLQGCVQKAYEDKVSALQRSLMEKEKLLQRLE 1810
Cdd:COG1196    749 EEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 483-1359 7.09e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.98  E-value: 7.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  483 SWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQE 562
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  563 QMKIALEKSQSEYLKITQEKEQQESLALEElelqkkaiLMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSED 642
Cdd:pfam02463  243 QELLRDEQEEIESSKQEIEKEEEKLAQVLK--------ENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEE 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  643 LAIHLEAEKNKHNKEItimvEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIE 722
Cdd:pfam02463  315 KLKESEKEKKKAEKEL----KKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAA 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  723 EMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQR 802
Cdd:pfam02463  391 KLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKS 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  803 TEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLL 882
Cdd:pfam02463  471 EDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVI 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  883 DLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEK 962
Cdd:pfam02463  551 VEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILK 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  963 ENVILQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELenTV 1042
Cdd:pfam02463  631 DTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ--RE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1043 LELSQKEKQFNAKILEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEELQEQHEIQLQEK 1122
Cdd:pfam02463  709 KEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1123 EQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRE 1202
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1203 NTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQ 1282
Cdd:pfam02463  869 LQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEK 948

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1753147357 1283 AKTNELINISSNKINAILARISHCQNHTTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQI 1359
Cdd:pfam02463  949 EKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLEL 1025
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1079-1752 7.25e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 7.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1079 KEQIESLTEVHRRELSDVvsvwEKRLNqqaeELQEQHEIQLQEKEQEVAELKQKILRSACEKEEMnreLAWLKEEGVKQN 1158
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDL----QRRLN----ESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM---ADIRRRESQSQE 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1159 TAVRELQEQLHQQSAqtnSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKVFElTDKLKTTdaQF 1238
Cdd:pfam15921  142 DLRNQLQNTVHELEA---AKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYE-HDSMSTM--HF 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1239 QSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIY----SKKTEALLQA---KTNELINISSNKINAILARISHCQNHTT 1311
Cdd:pfam15921  216 RSLGSAISKILRELDTEISYLKGRIFPVEDQLEALksesQNKIELLLQQhqdRIEQLISEHEVEITGLTEKASSARSQAN 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1312 KVKEALVIKTCKASELEAQ-LRQLTEEQNT---LNSSFQQATR----QLEEKENQIKSMKADIEGLVMEKEALQREGGNQ 1383
Cdd:pfam15921  296 SIQSQLEIIQEQARNQNSMyMRQLSDLESTvsqLRSELREAKRmyedKIEELEKQLVLANSELTEARTERDQFSQESGNL 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1384 QQAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNSISLTEkeAAISSLSKRYEEQQREL 1463
Cdd:pfam15921  376 DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLK--AMKSECQGQMERQMAAI 453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1464 LGQVQDLSlKVETLSKEKVSALEQVDHLSNKFSEWKKKAQSKfiqyHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQ 1543
Cdd:pfam15921  454 QGKNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESS----ERTVSDLTASLQEKERAIEATNAEITKLRSRVDL 528

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1544 QNERLVCLKGEMED-KKSKLEKKECNLETELKTQTARIVELQ-EHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQH 1621
Cdd:pfam15921  529 KLQELQHLKNEGDHlRNVQTECEALKLQMAEKDKVIEILRQQiENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQE 608

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1622 IQELGEEKDNRVKEAEEKVSRLE----------------------------KQVSSMKSELETKKKELEHANSGMKGKEE 1673
Cdd:pfam15921  609 FKILKDKKDAKIRELEARVSDLElekvklvnagserlravkdikqerdqllNEVKTSRNELNSLSEDYEVLKRNFRNKSE 688

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 1674 ELKALEDRLELESAAKLAELKKkaeqkiaaiKKQLLSQMEEKEQQYKKDTEGhlgeLNTKLQEKEREIQVLEEKLQSVE 1752
Cdd:pfam15921  689 EMETTTNKLKMQLKSAQSELEQ---------TRNTLKSMEGSDGHAMKVAMG----MQKQITAKRGQIDALQSKIQFLE 754
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1569-1815 1.59e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1569 LETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDT--EQKEMLQKLQHIQELGEEK------DNRVKEAEEKV 1640
Cdd:COG4913    615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYswDEIDVASAEREIAELEAELerldasSDDLAALEEQL 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1641 SRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLELESAAKLAELKKKAEQKIAAIKKqllsqmEEKEQQYK 1720
Cdd:COG4913    695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG------DAVERELR 768

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1721 KDTEGHLGELNTKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAA-CAEQEEAGLqgcvqKAYEDKVSALQRSL 1799
Cdd:COG4913    769 ENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLAlLDRLEEDGL-----PEYEERFKELLNEN 843

                          250
                   ....*....|....*...
gi 1753147357 1800 MEKEK--LLQRLEQEKEE 1815
Cdd:COG4913    844 SIEFVadLLSKLRRAIRE 861
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 539-905 1.87e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 1.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  539 EEELASKEQELTKKFQT--QERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKkAILMESENKLRDLQQEAE 616
Cdd:TIGR02169  676 LQRLRERLEGLKRELSSlqSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK-ERLEELEEDLSSLEQEIE 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  617 TYRTRILELESSLEKsLQESKNQSEDLAIHLEAEKNKHN-KEITIMVEKHKTELESLQHQQDTLwTEKLQVLKQEHQTEM 695
Cdd:TIGR02169  755 NVKSELKELEARIEE-LEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREI-EQKLNRLTLEKEYLE 832

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  696 EKLreKHEQEKETLLKDKESLFQAHIEEMN---EKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQadkvKQ 772
Cdd:TIGR02169  833 KEI--QELQEQRIDLKEQIKSIEKEIENLNgkkEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK----IE 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  773 ELEAKLDEQKSHHQQQVESIikeqemsiqrteKELKDEINQLGLLLKEkDKHLKEQQAHVENLEADIKRSEEELQQasak 852
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKL------------EALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEEIRA---- 969

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1753147357  853 lalFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDV 905
Cdd:TIGR02169  970 ---LEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1502-1719 2.52e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 52.14  E-value: 2.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1502 AQSKFIQYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIV 1581
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1582 ELQEH-----LTQKITEIESLNEALNKYNQQKD--TEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSEL 1654
Cdd:COG3883     94 ALYRSggsvsYLDVLLGSESFSDFLDRLSALSKiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357 1655 ETKKKELEHANSGMKGKEEELKALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQY 1719
Cdd:COG3883    174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1904-2195 2.63e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 2.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1904 QILEQKIKELDSCL-VREREGHRVEMEELTskfEKLQALQQQMEGKNKPTEALEESAEEkskshvvqprlpgnMEAEHND 1982
Cdd:COG1196    216 RELKEELKELEAELlLLKLRELEAELEELE---AELEELEAELEELEAELAELEAELEE--------------LRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1983 LEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEhQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLmrefhtQLAQ 2062
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEER-RRELEERLEELEEELAELEEELEELEEELEELEEELE------EAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2063 KDQELEMTIKETIDKAQDVEAELLE------SHQEETNQLYKKIAEKEDDLQRTAKRYEEILDAREEEMTAKVMDLQTQL 2136
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEaeeeleELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 2137 EELQNKYQERLQQEEspgnDKITIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRL 2195
Cdd:COG1196    432 ELEEEEEEEEEALEE----AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
753-937 2.72e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  753 RNKLEEELSVLKDQADKVKQEL-EAKLDEQKSHHQQQvesiiKEQEMSIQRTEKELKDEINQLglllkeKDKHLKEQQAH 831
Cdd:COG4913    271 LAELEYLRAALRLWFAQRRLELlEAELEELRAELARL-----EAELERLEARLDALREELDEL------EAQIRGNGGDR 339

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  832 VENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQK----LLDLETERILLTEQVAEVETQKKDVCT 907
Cdd:COG4913    340 LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEaaalLEALEEELEALEEALAEAEAALRDLRR 419

                          170       180       190
                   ....*....|....*....|....*....|
gi 1753147357  908 ELDthkiQVRDLLQQLENQKSEMEEKLQAL 937
Cdd:COG4913    420 ELR----ELEAEIASLERRKSNIPARLLAL 445
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1524-1766 3.94e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1524 TKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKkecnLETELKTQTARIVELQEHLTQKITEIESLNEALNK 1603
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA----LERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1604 YNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEhansGMKGKEEELKALEDRLE 1683
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE----ELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1684 LESAAKLAELKKKAEQKiaaikKQLLSQMEEKEQQYKK--DTEGHLGELNTKLQEKEREIQVLEEKLQSVEGPPQSEASA 1761
Cdd:COG4942    171 AERAELEALLAELEEER-----AALEALKAERQKLLARleKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245


                   ....*
gi 1753147357 1762 VPRSA 1766
Cdd:COG4942    246 AGFAA 250
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1525-2138 5.35e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1525 KEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKEC-NLETELKTQTARIVELQEHLTQKITEIESLNEALnk 1603
Cdd:COG4913    255 EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELeELRAELARLEAELERLEARLDALREELDELEAQI-- 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1604 ynQQKDTEQKEMLQKLqhIQELGEEKDNRvkeaEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLE 1683
Cdd:COG4913    333 --RGNGGDRLEQLERE--IERLERELEER----ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1684 lESAAKLAELKKKAEQKIAAIKKQLlSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQ----------SVEG 1753
Cdd:COG4913    405 -EALAEAEAALRDLRRELRELEAEI-ASLERRKSNIPARLLALRDALAEALGLDEAELPFVGELIEvrpeeerwrgAIER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1754 -----------PPQSEASAvprsaehmAACAEQEEAGLQGCVQKAYEDKVSALQRSLmEKEKLLQRLEqekeemVSSH-- 1820
Cdd:COG4913    483 vlggfaltllvPPEHYAAA--------LRWVNRLHLRGRLVYERVRTGLPDPERPRL-DPDSLAGKLD------FKPHpf 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1821 -----SEMQGRYQelLIKIEHAEA-KQHEDQIMIN---HLQKELEEKSKNySLIASQHVEeegGKNNIGAKQNLENVVDD 1891
Cdd:COG4913    548 rawleAELGRRFD--YVCVDSPEElRRHPRAITRAgqvKGNGTRHEKDDR-RRIRSRYVL---GFDNRAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1892 VQKTLQEKELACQILEQKIKELDS--CLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKShvvq 1969
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQErrEALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEEL---- 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1970 prlpgnmEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQEMEEKIKQEQEDlelkhnSTL 2049
Cdd:COG4913    698 -------EAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD------AVE 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2050 KQLMREFHTQLAQKDQELEMTIKETIDKAQ-------------DVEAELLESHQEETNQLykkiaeKEDDLqrtAKRYEE 2116
Cdd:COG4913    765 RELRENLEERIDALRARLNRAEEELERAMRafnrewpaetadlDADLESLPEYLALLDRL------EEDGL---PEYEER 835

                          650       660
                   ....*....|....*....|..
gi 1753147357 2117 ILDAREEEMTAKVMDLQTQLEE 2138
Cdd:COG4913    836 FKELLNENSIEFVADLLSKLRR 857
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 792-1365 6.11e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 6.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  792 IIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASE 871
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLN 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  872 EHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDT---------HKIQVRDLLQ----QLENQKSEMEEKLQALT 938
Cdd:TIGR04523  159 NKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKlelllsnlkKKIQKNKSLEsqisELKKQNNQLKDNIEKKQ 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  939 QRYESQLRDTNTEQAQTKQNLIEKENVILQMREGQsKEIETLKQKLSAKEDSFSVLHEEYEI---------------KFK 1003
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ-KELEQNNKKIKELEKQLNQLKSEISDlnnqkeqdwnkelksELK 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1004 NQEKKMEKIKQKAKEMQETLkKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANSAGISdavsrlETNQKEQIE 1083
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKII-SQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS------YKQEIKNLE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1084 SLTEVHRRELSDVvsvweKRLNQQAEELQEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRE 1163
Cdd:TIGR04523  391 SQINDLESKIQNQ-----EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRES 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1164 LQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQS 1243
Cdd:TIGR04523  466 LETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1244 shERNEKSLEDKSLEFKKLSEELAVQLEiYSKKTEALLQAKTNELINISSNKINAILARISHCQNHTTKVKEalviKTCK 1323
Cdd:TIGR04523  546 --ELNKDDFELKKENLEKEIDEKNKEIE-ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISS----LEKE 618

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1753147357 1324 ASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKAD 1365
Cdd:TIGR04523  619 LEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
PRK12704 PRK12704
phosphodiesterase; Provisional
 878-1049 6.18e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 51.32  E-value: 6.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  878 QQKLLDLETERILLTEQV-AEVETQKKDVCTELdthKIQVRDLLQQLENQKSEMEEKLQALtqryESQLRDtnteqaqtK 956
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAkKEAEAIKKEALLEA---KEEIHKLRNEFEKELRERRNELQKL----EKRLLQ--------K 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  957 QNLIEKENVILQMREgqsKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKI----KQKAKEMQ-ETLKKKLLDQE 1031
Cdd:PRK12704    95 EENLDRKLELLEKRE---EELEKKEKELEQKQQELEKKEEELEELIEEQLQELERIsgltAEEAKEILlEKVEEEARHEA 171

                          170
                   ....*....|....*...
gi 1753147357 1032 AKLKKELENTVLELSQKE 1049
Cdd:PRK12704   172 AVLIKEIEEEAKEEADKK 189
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1630-1832 1.05e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 1.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1630 DNRVKEAEEKVSRLEKQVSSMKSELETKKKELEH--ANSGMKGKEEELKALEDRLElESAAKLAELK---KKAEQKIAAI 1704
Cdd:COG3206    167 ELRREEARKALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLS-ELESQLAEARaelAEAEARLAAL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1705 KKQLLSQMEEKE--------QQYKK---DTEGHLGELNTKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACA 1773
Cdd:COG3206    246 RAQLGSGPDALPellqspviQQLRAqlaELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEAL 325

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 1774 EQEEAGLQGcVQKAYEDKVSALQrslmEKEKLLQRLEQEKEEMVSSHSEMQGRYQELLI 1832
Cdd:COG3206    326 QAREASLQA-QLAQLEARLAELP----ELEAELRRLEREVEVARELYESLLQRLEEARL 379
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2228-2267 1.18e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 44.27  E-value: 1.18e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1753147357 2228 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2267
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 335-733 1.29e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 1.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  335 LEVLQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKE-LHMAEKTKLITQLRDAKNLIEQLE 413
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdLARLEAEVEQLEERIAQLSKELTE 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  414 QDKGMVIAETKR-QMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKeKSEKAAFEELEKALSTAQKAEESWRKMKAEVD 492
Cdd:TIGR02168  759 LEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKALREAL-DELRAELTLLNEEAANLRERLESLERRIAATE 837

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  493 EQIKAIEKTREEErtslqlelsrvkqeavdvmkksSEQIVKLQKLHEEelaskeqeltkkFQTQERQFQEQMKIALEKSQ 572
Cdd:TIGR02168  838 RRLEDLEEQIEEL----------------------SEDIESLAAEIEE------------LEELIEELESELEALLNERA 883

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  573 SEYLKITQEKEQQESLALEELELQKKAilMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKN 652
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKR--SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALEN 961

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  653 KHNKEItimvEKHKTELESLQHQQDTLWTEKLQVLkqehqTEMEKLREKHE---QEKETLLKDKESLFQAhIEEMNEKTF 729
Cdd:TIGR02168  962 KIEDDE----EEARRRLKRLENKIKELGPVNLAAI-----EEYEELKERYDfltAQKEDLTEAKETLEEA-IEEIDREAR 1031


                   ....
gi 1753147357  730 EKLD 733
Cdd:TIGR02168 1032 ERFK 1035
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1108-1361 2.02e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1108 AEELQEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQSAQTNSLSQNETKLKA 1187
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1188 QLEKLEGDlnhslrentsLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLsEELA 1267
Cdd:COG4942     98 ELEAQKEE----------LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL-AALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1268 VQLEIYSKKTEALLQAKTNELINISSNKinailarishcqnhtTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQ 1347
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALK---------------AERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                          250
                   ....*....|....
gi 1753147357 1348 ATRQLEEKENQIKS 1361
Cdd:COG4942    232 LEAEAAAAAERTPA 245
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 468-1377 2.14e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 2.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  468 EELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEertslqlelsRVKQEAVDVMKKsseqivKLQKLHEEELASKEQ 547
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE----------REKAERYQALLK------EKREYEGYELLKEKE 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  548 ELTKKFQTQERQFQEqmkiaLEKSQSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELES 627
Cdd:TIGR02169  234 ALERQKEAIERQLAS-----LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  628 SLEKSLQESKNQSEDLAIhLEAEKNKHNKEItimvEKHKTELESLQHQQDTLWTEKlqvlkQEHQTEMEKLREKHEQEke 707
Cdd:TIGR02169  309 SIAEKERELEDAEERLAK-LEAEIDKLLAEI----EELEREIEEERKRRDKLTEEY-----AELKEELEDLRAELEEV-- 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  708 tllkdkeslfqahiEEMNEKTFEKLDvkqteleslsselsdilkarnKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQ 787
Cdd:TIGR02169  377 --------------DKEFAETRDELK---------------------DYREKLEKLKREINELKRELDRLQEELQRLSEE 421

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  788 QVEsiikeqemsIQRTEKELKDEINQLglllkekdkhlkeqQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQA 867
Cdd:TIGR02169  422 LAD---------LNAAIAGIEAKINEL--------------EEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY 478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  868 KASEEHLAQLQQKLLDLETERILLTEQVAEvetqKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQ-ALTQRYESQLR 946
Cdd:TIGR02169  479 DRVEKELSKLQRELAEAEAQARASEERVRG----GRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvAAGNRLNNVVV 554

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  947 DTNTEQAQTKQNLIEKEN---VILQMREGQSKEIETLKQKLSAKEDsFSVLHEEYEIKFKNQEKK-------MEKIKQKA 1016
Cdd:TIGR02169  555 EDDAVAKEAIELLKRRKAgraTFLPLNKMRDERRDLSILSEDGVIG-FAVDLVEFDPKYEPAFKYvfgdtlvVEDIEAAR 633

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1017 KEMQE----TLKKKLLDQE------AKLKKELENTVLELSQKEKQFNAKILEMaQANSAGISDAVSRLETNQKEQIESLT 1086
Cdd:TIGR02169  634 RLMGKyrmvTLEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGL-KRELSSLQSELRRIENRLDELSQELS 712

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1087 EVHR--RELSDVVSVWEKRLNQQAEELqEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKE-----------E 1153
Cdd:TIGR02169  713 DASRkiGEIEKEIEQLEQEEEKLKERL-EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEalndlearlshS 791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1154 GVKQNTA-VRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKVFELTDKLK 1232
Cdd:TIGR02169  792 RIPEIQAeLSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1233 TTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAKTnelinissnKINAILARISHCQNHTTK 1312
Cdd:TIGR02169  872 ELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA---------KLEALEEELSEIEDPKGE 942

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357 1313 VKEaLVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQ 1377
Cdd:TIGR02169  943 DEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 820-1661 2.31e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  820 EKDKHLKEQQAHVENLEADIKRSEEELQ-QASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEV 898
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKeQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  899 ETQKKDVCTEldthKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMREGQSKEIE 978
Cdd:pfam02463  256 SKQEIEKEEE----KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  979 TLKQKLSAKEDSFSvLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNA--KI 1056
Cdd:pfam02463  332 KEKEEIEELEKELK-ELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEaqLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1057 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVAELKQKILRS 1136
Cdd:pfam02463  411 LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1137 ACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQSAQ--TNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELE 1214
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHgrLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1215 MLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAKTNELINISSN 1294
Cdd:pfam02463  571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1295 KINAILARISHCQNhTTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKE 1374
Cdd:pfam02463  651 GVSLEEGLAEKSEV-KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQE 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1375 ALQREGGNQQQAASEKESCI-TQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNSISLTEKEAAISSLS 1453
Cdd:pfam02463  730 AQDKINEELKLLKQKIDEEEeEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1454 KRYEEQQRELLGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEWKKkaqskfiqyhSTNKELQMQLELKTKEVSEKAEQ 1533
Cdd:pfam02463  810 LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEEL----------ERLEEEITKEELLQELLLKEEEL 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1534 IHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQK 1613
Cdd:pfam02463  880 EEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEE 959

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*...
gi 1753147357 1614 EMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKEL 1661
Cdd:pfam02463  960 ERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKL 1007
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1323-1683 2.39e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 2.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1323 KASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLvmeKEALQREGGNQQQAASEKEscitqlkkELS 1402
Cdd:PRK02224   350 DADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEEL---RERFGDAPVDLGNAEDFLE--------ELR 418

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1403 ENINAVTlmkeelkekkseisslsKQLTDLNTQLQNSISLTEKEAAISSLSKRYEEQQ----RELLGQVQDLSLKVETLS 1478
Cdd:PRK02224   419 EERDELR-----------------EREAELEATLRTARERVEEAEALLEAGKCPECGQpvegSPHVETIEEDRERVEELE 481

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1479 KEKVSALEQVDHLSNKFSEWK--KKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQ-----QNERLVCL 1551
Cdd:PRK02224   482 AELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAEleaeaEEKREAAA 561

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1552 KGEMEDKKSKLEKKECNLE-TELKT---QTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGE 1627
Cdd:PRK02224   562 EAEEEAEEAREEVAELNSKlAELKErieSLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEA 641

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1628 EKD-NRVKEAEEKVSRLEK---QVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLE 1683
Cdd:PRK02224   642 EFDeARIEEAREDKERAEEyleQVEEKLDELREERDDLQAEIGAVENELEELEELRERRE 701
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1514-2197 2.76e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 2.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1514 KELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITE 1593
Cdd:pfam02463  207 KKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1594 IESLNEALNKynqqkdtEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEE 1673
Cdd:pfam02463  287 ELKLLAKEEE-------ELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1674 ELKALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQME----------------------EKEQQYKKDTEGHLGELN 1731
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELkseeekeaqlllelarqledllKEEKKEELEILEEEEESI 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1732 TKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDkVSALQRSLMEKEKLLQRLEQ 1811
Cdd:pfam02463  440 ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEER-SQKESKARSGLKVLLALIKD 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1812 EKEEMVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELEEKSKNYSLIASQHVEEEGGKNNIGAKQNLENVVDD 1891
Cdd:pfam02463  519 GVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLE 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1892 VQKTLQEKELACQILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPR 1971
Cdd:pfam02463  599 IDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEI 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1972 LPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQ 2051
Cdd:pfam02463  679 QELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLK 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2052 LMREFHTQLAQKDQELEMTIKETIDKAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAKRYEEILDAREEEMTAKVMD 2131
Cdd:pfam02463  759 KEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL 838

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1753147357 2132 LQTQLEELQNKYQERLQQEESPGNDKITIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKK 2197
Cdd:pfam02463  839 ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEE 904
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1930-2200 2.90e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.67  E-value: 2.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1930 ELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVqprlpgnMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLR 2009
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEE-------LRLEVSELEEEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2010 MLRKEhQQELDIMKKEYEQEMEEKIKQEQEDLE-LKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAELLE- 2087
Cdd:TIGR02168  306 ILRER-LANLERQLEELEAQLEELESKLDELAEeLAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETl 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2088 -----SHQEETNQLYKKIAEKEDDLQRTAKRYE----EILDAREEEMTAKVMDLQTQLEELQnkyQERLQQEESPGNDKI 2158
Cdd:TIGR02168  385 rskvaQLELQIASLNNEIERLEARLERLEDRRErlqqEIEELLKKLEEAELKELQAELEELE---EELEELQEELERLEE 461

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1753147357 2159 TIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2200
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 666-1734 2.99e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 49.66  E-value: 2.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  666 KTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNeKTFEKLDVKQTELESLSSE 745
Cdd:TIGR01612  695 KAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLN-KILEDFKNKEKELSNKIND 773

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  746 LSDILKARNKLEEELSVLKDQ------ADKVKQElEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEInqlgllLK 819
Cdd:TIGR01612  774 YAKEKDELNKYKSKISEIKNHyndqinIDNIKDE-DAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDF------LN 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  820 EKDKHLKEQQAHVENLEADIKRSEEELQQASAKLAlfqSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVE 899
Cdd:TIGR01612  847 KVDKFINFENNCKEKIDSEHEQFAELTNKIKAEIS---DDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVDEYI 923

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  900 TQKKDVCTELDTHKIQvRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEqaqtKQNLIEKENVILQMREGQSKEIET 979
Cdd:TIGR01612  924 KICENTKESIEKFHNK-QNILKEILNKNIDTIKESNLIEKSYKDKFDNTLID----KINELDKAFKDASLNDYEAKNNEL 998

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  980 LKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEM 1059
Cdd:TIGR01612  999 IKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIELLNKEILEE 1078

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1060 AQANSAGISDAVSRL------------------ETNQ-KEQIESLTEV---HRRELSDVVSVWEKRLNQ---QAEELQEQ 1114
Cdd:TIGR01612 1079 AEINITNFNEIKEKLkhynfddfgkeenikyadEINKiKDDIKNLDQKidhHIKALEEIKKKSENYIDEikaQINDLEDV 1158

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1115 HEIQLQEKEQEVAELKQKILRSACEK-----EEMNRELAWLKEEGvKQNTAVRELQ--EQLHQQSAQTNSLSQ-NETKLK 1186
Cdd:TIGR01612 1159 ADKAISNDDPEEIEKKIENIVTKIDKkkniyDEIKKLLNEIAEIE-KDKTSLEEVKgiNLSYGKNLGKLFLEKiDEEKKK 1237

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1187 AQ-----LEKLEGDLnhslrENTSLQERMVELEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKK 1261
Cdd:TIGR01612 1238 SEhmikaMEAYIEDL-----DEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIE 1312

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1262 LSEELAVQLEIYSKKTEALLQA-KTNELINISSNKINAI--LARISHCQNHTTKVKEAlviktckASELEAQLRQLTEEQ 1338
Cdd:TIGR01612 1313 DFSEESDINDIKKELQKNLLDAqKHNSDINLYLNEIANIynILKLNKIKKIIDEVKEY-------TKEIEENNKNIKDEL 1385

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1339 ntlnSSFQQATRQLEEKENqIKSMKADIEGLVMEK---EALQREGGNQQQAASEkESCITQLKKELSENINAVTLMKEEL 1415
Cdd:TIGR01612 1386 ----DKSEKLIKKIKDDIN-LEECKSKIESTLDDKdidECIKKIKELKNHILSE-ESNIDTYFKNADENNENVLLLFKNI 1459

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1416 KEKKSEISSLSKQLTDLNT--------QLQNSISLTEKEAAISSLSKRYEEQQRELLGQVQdlslKVETLSKEKVSALEq 1487
Cdd:TIGR01612 1460 EMADNKSQHILKIKKDNATndhdfninELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYK----KDVTELLNKYSALA- 1534

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1488 vdhLSNKFSEWKKKAQSKFIQYHSTNKELQMQL---ELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEK 1564
Cdd:TIGR01612 1535 ---IKNKFAKTKKDSEIIIKEIKDAHKKFILEAeksEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK 1611

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1565 kecnletelktqtarIVELQEHLTQKITEIESLNEALNKYN-QQKDTEQKEMLQKLQHIQELGEEKDNRvkeaeekvsrl 1643
Cdd:TIGR01612 1612 ---------------ISDIKKKINDCLKETESIEKKISSFSiDSQDTELKENGDNLNSLQEFLESLKDQ----------- 1665

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1644 ekqvssmKSELETKKKELEHANSGMKGKEEELKALEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKK-- 1721
Cdd:TIGR01612 1666 -------KKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTnd 1738

                         1130
                   ....*....|....*..
gi 1753147357 1722 ----DTEGHLGELNTKL 1734
Cdd:TIGR01612 1739 legiDPNEKLEEYNTEI 1755
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
335-571 3.09e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 3.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  335 LEVLQQRVKRQENLLQRCKETIQshkeqcalltsEKEALQEQLDERLQELEKMKELHMAEK--TKLITQLRDAKNLIEQL 412
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLE-----------ALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  413 EQDKGMVIA---------ETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALST---AQKA 480
Cdd:COG4913    681 DASSDDLAAleeqleeleAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEErfaAALG 760

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  481 EESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQE------AVDVMKKSSEQIVK-LQKLHEEELASKEQELTKKF 553
Cdd:COG4913    761 DAVERELRENLEERIDALRARLNRAEEELERAMRAFNREwpaetaDLDADLESLPEYLAlLDRLEEDGLPEYEERFKELL 840

                          250
                   ....*....|....*...
gi 1753147357  554 QTQERQFQEQMKIALEKS 571
Cdd:COG4913    841 NENSIEFVADLLSKLRRA 858
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1936-2154 3.29e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1936 EKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEH 2015
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2016 QQELDIMKKEYEQEMEEKIKQEQEDLELKHNST-LKQLMREFHTQLAQ--KDQELEMTIKETIDKAQDVEAELLESHQEE 2092
Cdd:COG4942    107 AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQyLKYLAPARREQAEElrADLAELAALRAELEAERAELEALLAELEEE 186

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1753147357 2093 TNQLYKKIAEKEDDLQRTAKRYEEiLDAREEEMTAKVMDLQTQLEELQNKYQERLQQEESPG 2154
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAE-LAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 329-1022 3.60e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 3.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  329 GASAKTLEVLQQRVKR----QENLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRD 404
Cdd:TIGR02169  268 EEIEQLLEELNKKIKDlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  405 AKNLIEQLeQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKaafeELEKALSTAQKAEESW 484
Cdd:TIGR02169  348 ERKRRDKL-TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR----ELDRLQEELQRLSEEL 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  485 RKMKAEVdEQIKAIEKTREEERTSLQLELSRVKQE---AVDVMKKSSEQIVKLQKLH---EEELASKEQELTKKFQTQER 558
Cdd:TIGR02169  423 ADLNAAI-AGIEAKINELEEEKEDKALEIKKQEWKleqLAADLSKYEQELYDLKEEYdrvEKELSKLQRELAEAEAQARA 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  559 QFQEQMKialEKSQSEYLK------------ITQEKEQQESLALEELELQKKAILMESE-------NKLRDLQQEAETY- 618
Cdd:TIGR02169  502 SEERVRG---GRAVEEVLKasiqgvhgtvaqLGSVGERYATAIEVAAGNRLNNVVVEDDavakeaiELLKRRKAGRATFl 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  619 -RTRILELESSLEKSlqeSKNQSEDLAIHLEAEKNKHNKEI------TIMVEKHKTELESL-QHQQDTLWTE-------- 682
Cdd:TIGR02169  579 pLNKMRDERRDLSIL---SEDGVIGFAVDLVEFDPKYEPAFkyvfgdTLVVEDIEAARRLMgKYRMVTLEGElfeksgam 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  683 --------KLQVLKQEHQTEMEKLREkheqEKETLLKDKESLFQ--AHIEEMNEKTFEKLDVKQTELESLSSELSDILKA 752
Cdd:TIGR02169  656 tggsraprGGILFSRSEPAELQRLRE----RLEGLKRELSSLQSelRRIENRLDELSQELSDASRKIGEIEKEIEQLEQE 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  753 RNKLEEELSVLKDQADKVKQELEAKLDEQKshhqqQVESIIKEQEMSIQRTEKELKD--------EINQLGLLLKEKDKH 824
Cdd:TIGR02169  732 EEKLKERLEELEEDLSSLEQEIENVKSELK-----ELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAELSKLEEE 806

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  825 LKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKD 904
Cdd:TIGR02169  807 VSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGD 886

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  905 VCTELDTHKIQVRDLLQQLENQKSEMEEKlqaltqryESQLRDTNTEQAQTKQNLIEKENVILQMREGQSKE--IETLKQ 982
Cdd:TIGR02169  887 LKKERDELEAQLRELERKIEELEAQIEKK--------RKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsLEDVQA 958

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1753147357  983 KLSAKEDSFSVLH-------EEYEI---KFKNQEKKMEKIKQKAKEMQET 1022
Cdd:TIGR02169  959 ELQRVEEEIRALEpvnmlaiQEYEEvlkRLDELKEKRAKLEEERKAILER 1008
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 338-1009 4.15e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 4.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  338 LQQRVKRQENLLQRCKETIQSHKEQCALLTSEKEALQEQLdeRLQELEKMKELHMAEKTKLITQLRDAKNLIEQ------ 411
Cdd:TIGR00618  217 YHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL--KKQQLLKQLRARIEELRAQEAVLEETQERINRarkaap 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  412 --LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKA 489
Cdd:TIGR00618  295 laAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQ 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  490 EVDEQ----IKAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMK 565
Cdd:TIGR00618  375 HTLTQhihtLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  566 IALEKSQSEYLKITQEKEQQESLALEELElQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAI 645
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRG 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  646 HLEaeknkhnkeitimVEKHKTELESLQHQQDTLwTEKLQVLK---QEHQTEMEKLREKHEQEKETL--LKDKESLFQAH 720
Cdd:TIGR00618  534 EQT-------------YAQLETSEEDVYHQLTSE-RKQRASLKeqmQEIQQSFSILTQCDNRSKEDIpnLQNITVRLQDL 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  721 IEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKsHHQQQVESIIKEQEMSI 800
Cdd:TIGR00618  600 TEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR-EHALSIRVLPKELLASR 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  801 QRTEKELKDEINQLGLLLKE---KDKHLKEQQAHVENLeadiKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQL 877
Cdd:TIGR00618  679 QLALQKMQSEKEQLTYWKEMlaqCQTLLRELETHIEEY----DREFNEIENASSSLGSDLAAREDALNQSLKELMHQART 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  878 QQKLLDLETERILLTEQVAE-VETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTK 956
Cdd:TIGR00618  755 VLKARTEAHFNNNEEVTAALqTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFL 834

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1753147357  957 QNLIEKENVILQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKM 1009
Cdd:TIGR00618  835 SRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 538-805 4.25e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 4.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  538 HEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEA-- 615
Cdd:pfam17380  280 HQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEErk 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  616 ---ETYRTRILELESS----LEKSLQESKNQSEDLAIHLEAEKNKH--NKEITIMVEKHKTELESLQHQQDTLWTEKLQV 686
Cdd:pfam17380  360 relERIRQEEIAMEISrmreLERLQMERQQKNERVRQELEAARKVKilEEERQRKIQQQKVEMEQIRAEQEEARQREVRR 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  687 LKQEHQTEMEKLREKH---------------EQEKETLLKDKESLFQAHIEEMNEKTFEKldvkqteleSLSSELSDILK 751
Cdd:pfam17380  440 LEEERAREMERVRLEEqerqqqverlrqqeeERKRKKLELEKEKRDRKRAEEQRRKILEK---------ELEERKQAMIE 510

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1753147357  752 ARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEK 805
Cdd:pfam17380  511 EERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE 564
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
374-952 4.46e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 4.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  374 QEQLDERLQ--ELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDkgmvIAETK-RQMHETLEMKEEEIAQLRSRIKQMTA 450
Cdd:PRK02224   152 QDMIDDLLQlgKLEEYRERASDARLGVERVLSDQRGSLDQLKAQ----IEEKEeKDLHERLNGLESELAELDEEIERYEE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  451 QGEELREQKEKSE----------------KAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQL--- 511
Cdd:PRK02224   228 QREQARETRDEADevleeheerreeletlEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLdda 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  512 ----------ELSRVKQEAVDVMKKSSEQIVKLQKLHE------EELASKEQELTKKFQTQERQFQEQmKIALEKSQSEY 575
Cdd:PRK02224   308 daeavearreELEDRDEELRDRLEECRVAAQAHNEEAEslredaDDLEERAEELREEAAELESELEEA-REAVEDRREEI 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  576 LKITQEKEQQESLALEELELqkkaiLMESENKLRDLQQEAETYRTRILELESSLeKSLQESKNQSEDLaihLEA------ 649
Cdd:PRK02224   387 EELEEEIEELRERFGDAPVD-----LGNAEDFLEELREERDELREREAELEATL-RTARERVEEAEAL---LEAgkcpec 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  650 ----EKNKHNKEIT---IMVEKHKTELESLQHQQDTLwTEKLQVLKQ--EHQTEMEKLREKHEQEKEtLLKDKEslfqAH 720
Cdd:PRK02224   458 gqpvEGSPHVETIEedrERVEELEAELEDLEEEVEEV-EERLERAEDlvEAEDRIERLEERREDLEE-LIAERR----ET 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  721 IEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKdqadkvkqELEAKLDEQKSHHQQ--QVESIIKEQEM 798
Cdd:PRK02224   532 IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVA--------ELNSKLAELKERIESleRIRTLLAAIAD 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  799 SIQRTEkELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIkrSEEELQQASAKlalfqsqqsttHEQAkasEEHLAQLQ 878
Cdd:PRK02224   604 AEDEIE-RLREKREALAELNDERRERLAEKRERKRELEAEF--DEARIEEARED-----------KERA---EEYLEQVE 666

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1753147357  879 QKLLDLETERILLTEQVAEVETQKKDVCTELDTHKiQVRDLLQQLENQKSEMEEkLQALTQRYESQLRDTNTEQ 952
Cdd:PRK02224   667 EKLDELREERDDLQAEIGAVENELEELEELRERRE-ALENRVEALEALYDEAEE-LESMYGDLRAELRQRNVET 738
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 353-643 4.47e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 4.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  353 KETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 428
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  429 ETLEMKEEEIAQLRSRIKQM-------TAQGEELREQKEKSEKAAFEELEKALST-----------AQKAEESWRKMKAE 490
Cdd:pfam17380  361 ELERIRQEEIAMEISRMRELerlqmerQQKNERVRQELEAARKVKILEEERQRKIqqqkvemeqirAEQEEARQREVRRL 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  491 VDEQIKAIEKTREEERTSlQLELSRVKQEAVDVMKKsseqivKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEK 570
Cdd:pfam17380  441 EEERAREMERVRLEEQER-QQQVERLRQQEEERKRK------KLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEER 513

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1753147357  571 SQSEYLKITQEKEQ---QESLALEELELQKKAILMESENKLRDLQQEAETYRTRI--LELESSLEKSLQESKNQSEDL 643
Cdd:pfam17380  514 KRKLLEKEMEERQKaiyEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLeaMEREREMMRQIVESEKARAEY 591
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 457-998 6.79e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 48.20  E-value: 6.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  457 EQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSL--QLELSRVKQEAVDVM-KKSSEQIVK 533
Cdd:pfam05557   19 KQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALreQAELNRLKKKYLEALnKKLNEKESQ 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  534 LQKLHEEELASKEQ--ELTKKFQTQERQFQEQMKiALEKSQsEYLKITQEKEQQESLALEELELQKKAiLMESENKLRDL 611
Cdd:pfam05557   99 LADAREVISCLKNElsELRRQIQRAELELQSTNS-ELEELQ-ERLDLLKAKASEAEQLRQNLEKQQSS-LAEAEQRIKEL 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  612 QQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTELESLQHQQdtlwtEKLQVLKQEH 691
Cdd:pfam05557  176 EFEIQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLERE-----EKYREEAATL 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  692 QTEMEKLREKheqeketlLKDKESLFQAHIEEMN-----EKTFEKLDVKQTELESLSSELSDILKARNKLEEELSVLKDQ 766
Cdd:pfam05557  251 ELEKEKLEQE--------LQSWVKLAQDTGLNLRspedlSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELAQ 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  767 ADKVKQELEAKLDEQKSHH---QQQVESIIKEQEMSIQRTEKELKDEIN-----QLGLLLKEKDKHLKEQQAHVENLEAD 838
Cdd:pfam05557  323 YLKKIEDLNKKLKRHKALVrrlQRRVLLLTKERDGYRAILESYDKELTMsnyspQLLERIEEAEDMTQKMQAHNEEMEAQ 402

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  839 IKRSEEEL-----QQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHK 913
Cdd:pfam05557  403 LSVAEEELggykqQAQTLERELQALRQQESLADPSYSKEEVDSLRRKLETLELERQRLREQKNELEMELERRCLQGDYDP 482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  914 IQVRDLLQQL------ENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMREGQSKEIETLKQKLSAK 987
Cdd:pfam05557  483 KKTKVLHLSMnpaaeaYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFKEVLDLRKELESAELKNQRL 562

                          570
                   ....*....|.
gi 1753147357  988 EDSFSVLHEEY 998
Cdd:pfam05557  563 KEVFQAKIQEF 573
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 806-1077 7.18e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 48.29  E-value: 7.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  806 ELKDEINQLGLLLKEkDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEehlAQLQQKLLDLE 885
Cdd:NF012221  1539 ESSQQADAVSKHAKQ-DDAAQNALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNALETN---GQAQRDAILEE 1614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  886 TERIllTEQVAEVeTQKKDVCTELDTHKIQ-------------VRDLLQQLENQKSEMEEKLQALTQRYESQLRD----- 947
Cdd:NF012221  1615 SRAV--TKELTTL-AQGLDALDSQATYAGEsgdqwrnpfagglLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKvkdav 1691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  948 --TNTEQAQTKQNLIEKENVILQMR-EGQSKEIETLKQKLSAKE---DSFSVLHEEY---EIKFKNQEKKMEKIKQKAKE 1018
Cdd:NF012221  1692 akSEAGVAQGEQNQANAEQDIDDAKaDAEKRKDDALAKQNEAQQaesDANAAANDAQsrgEQDASAAENKANQAQADAKG 1771

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1753147357 1019 MQET--------------LKKKLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANSAGISDAVSRLETN 1077
Cdd:NF012221  1772 AKQDesdkpnrqgaagsgLSGKAYSVEGVAEPGSHINPDSPAAADGRFSEGLTEQEQEALEGATNAVNRLQIN 1844
PRK01156 PRK01156
chromosome segregation protein; Provisional
 395-885 7.96e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.97  E-value: 7.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  395 KTKLITQLRDAKNLIEQLEQDKGM--VIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEK 472
Cdd:PRK01156   189 EEKLKSSNLELENIKKQIADDEKShsITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSME 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  473 ALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVK----LQKLHEE-ELASKEQ 547
Cdd:PRK01156   269 LEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKklsvLQKDYNDyIKKKSRY 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  548 ELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAI----------------LMESENKLRDL 611
Cdd:PRK01156   349 DDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEidpdaikkelneinvkLQDISSKVSSL 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  612 QQEAETYRTRILELESSLEKSLQESK----------NQSEDLAIHLEAEKNKHNKEIT---IMVEKHKTELESLQHQQDT 678
Cdd:PRK01156   429 NQRIRALRENLDELSRNMEMLNGQSVcpvcgttlgeEKSNHIINHYNEKKSRLEEKIReieIEVKDIDEKIVDLKKRKEY 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  679 LWTEKLQVLKQEHQtEMEKLRE--KHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTE--LESLSSELSDILKARN 754
Cdd:PRK01156   509 LESEEINKSINEYN-KIESARAdlEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSwlNALAVISLIDIETNRS 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  755 KLEEELSVLKDQADKVkQELEAKLDEQKSHHQQQVESIikEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVEN 834
Cdd:PRK01156   588 RSNEIKKQLNDLESRL-QEIEIGFPDDKSYIDKSIREI--ENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDS 664

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1753147357  835 LEADIK-------RSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLE 885
Cdd:PRK01156   665 IIPDLKeitsrinDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDIN 722
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 353-1229 8.42e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.12  E-value: 8.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  353 KETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKlitqlrdaknlieqLEQDKGMVIAETKRQMHETLE 432
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVR--------------QTQGQKVQEHQMELKYLKQYK 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  433 MKEEEIA-QLRSRIKQMTAQGEELREQKEKSEKaafeelekaLSTAQKAEESWRKMKAEVDEQIKAIEKTREE-ERTSLQ 510
Cdd:TIGR00606  217 EKACEIRdQITSKEAQLESSREIVKSYENELDP---------LKNRLKEIEHNLSKIMKLDNEIKALKSRKKQmEKDNSE 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  511 LELSRVKqeavdVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSqseylkitqekeqqeslal 590
Cdd:TIGR00606  288 LELKMEK-----VFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKT------------------- 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  591 eelelqkkailmESENKLRDLQQEAETYRTRILELESS-LEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEKHKTEL 669
Cdd:TIGR00606  344 ------------ELLVEQGRLQLQADRHQEHIRARDSLiQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAA 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  670 ESLQHQQDTLWTEKLQVLKQEhqTEMEKLREKHEQEKETLLKDKESL----FQAHIEEMNEKTFEKLDVKQTELESLSSE 745
Cdd:TIGR00606  412 QLCADLQSKERLKQEQADEIR--DEKKGLGRTIELKKEILEKKQEELkfviKELQQLEGSSDRILELDQELRKAERELSK 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  746 LSDILKARNKLEEELSVLKDQADKVKQEL-EAKLDEQKSHHQQ---QVESIIKEQEMSIQRTEKELKDEINQL-GLLLKE 820
Cdd:TIGR00606  490 AEKNSLTETLKKEVKSLQNEKADLDRKLRkLDQEMEQLNHHTTtrtQMEMLTKDKMDKDEQIRKIKSRHSDELtSLLGYF 569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  821 KDKHLKEQQAHveNLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDL---ETERILLTEQVAE 897
Cdd:TIGR00606  570 PNKKQLEDWLH--SKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLERLKEE 647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  898 VETQKKDVCTELDTHKIQVRDLLQQLENQKS---------EMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKE---NV 965
Cdd:TIGR00606  648 IEKSSKQRAMLAGATAVYSQFITQLTDENQSccpvcqrvfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEkrrDE 727

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  966 ILQMREGQSKEIETLKQKLsakedsfsvlhEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLEL 1045
Cdd:TIGR00606  728 MLGLAPGRQSIIDLKEKEI-----------PELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMER 796

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1046 SQKEKQFNAKILEMAQANSAGISDAVSRLETNQKEQIEsltevhRRELSDVVSvwEKRLNQQAEELQEQHEIQLQEKEQE 1125
Cdd:TIGR00606  797 FQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEK------QHELDTVVS--KIELNRKLIQDQQEQIQHLKSKTNE 868

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1126 VAELKQKILRSACEKEEMNRELAwlkeegvkqnTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNhslRENTS 1205
Cdd:TIGR00606  869 LKSEKLQIGTNLQRRQQFEEQLV----------ELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELIS---SKETS 935

                          890       900
                   ....*....|....*....|....
gi 1753147357 1206 LQERMVELEMLAEKDKLKVFELTD 1229
Cdd:TIGR00606  936 NKKAQDKVNDIKEKVKNIHGYMKD 959
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
751-1249 9.01e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 9.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  751 KARNKLEEELSVL---KDQADKVKQELEAKLD--EQKSHHQQQVESIIKEQEMSIQRTEKE---LKDEI----NQLGLLL 818
Cdd:PRK02224   213 SELAELDEEIERYeeqREQARETRDEADEVLEehEERREELETLEAEIEDLRETIAETEREreeLAEEVrdlrERLEELE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  819 KEKDKHLKEQ----------QAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETER 888
Cdd:PRK02224   293 EERDDLLAEAglddadaeavEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESEL 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  889 ILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEklqaltqrYESQLRDTNTEQAQTKQNLIEKENVILQ 968
Cdd:PRK02224   373 EEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEE--------LREERDELREREAELEATLRTARERVEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  969 MRE----------GQSKEIETLKQKLSAKEDSFSVLHEEYEiKFKNQEKKMEKIKQKAKEMQETlkkklLDQEAKLKKEL 1038
Cdd:PRK02224   445 AEAlleagkcpecGQPVEGSPHVETIEEDRERVEELEAELE-DLEEEVEEVEERLERAEDLVEA-----EDRIERLEERR 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1039 ENTVLELSQKEKQFNAKILEMAQANsagisDAVSRLETNQKEQIESLTEVHRR--ELSDVVSVWEKRLNQQAEELQEQHE 1116
Cdd:PRK02224   519 EDLEELIAERRETIEEKRERAEELR-----ERAAELEAEAEEKREAAAEAEEEaeEAREEVAELNSKLAELKERIESLER 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1117 IQ-----LQEKEQEVAELKQKiLRSACEKEEMNRElaWLKEegvkQNTAVRELQEQLhqQSAQTNSLSQNETKLKAQLEK 1191
Cdd:PRK02224   594 IRtllaaIADAEDEIERLREK-REALAELNDERRE--RLAE----KRERKRELEAEF--DEARIEEAREDKERAEEYLEQ 664

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1753147357 1192 LEGDLNHSLRENTSLQERMVELEmlAEKDKLKvfELTDKLKTTDAQFQSLQSSHERNE 1249
Cdd:PRK02224   665 VEEKLDELREERDDLQAEIGAVE--NELEELE--ELRERREALENRVEALEALYDEAE 718
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1541-2116 9.97e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 9.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1541 LDQQNERLVCLKGEMEDKKSK-LEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKD--TEQKEMLQ 1617
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKEEKdLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREelETLEAEIE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1618 KLQH-IQELGEEKDN---RVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLElESAAKLAEL 1693
Cdd:PRK02224   262 DLREtIAETEREREElaeEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE-ECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1694 KKKAEQKIAAIKkQLLSQMEEKEQQyKKDTEGHLGELNTKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACA 1773
Cdd:PRK02224   341 NEEAESLREDAD-DLEERAEELREE-AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELR 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1774 EqEEAGLQGCVqKAYEDKVSALQRSLMEKEKLLQ-----RLEQEKEEmvSSHSEMQGRYQELLIKIEhAEAKQHEDQimi 1848
Cdd:PRK02224   419 E-ERDELRERE-AELEATLRTARERVEEAEALLEagkcpECGQPVEG--SPHVETIEEDRERVEELE-AELEDLEEE--- 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1849 nhlQKELEEKSKNYSLIASQHVEEEGGKNNigaKQNLENVVDDVQKTLQEKELACQILEQKIKELDSCLVREREGHRVEM 1928
Cdd:PRK02224   491 ---VEEVEERLERAEDLVEAEDRIERLEER---REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAE 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1929 EELTSKFEKLQALQQQMEGKNKPTEALEesaeekskshvvqprlpgnmeaehndlefKLAGAEQEKQKLGKEIVKLQKdl 2008
Cdd:PRK02224   565 EEAEEAREEVAELNSKLAELKERIESLE-----------------------------RIRTLLAAIADAEDEIERLRE-- 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2009 rmlRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEmTIKETIDKAQDvEAELLES 2088
Cdd:PRK02224   614 ---KREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLD-ELREERDDLQA-EIGAVEN 688

                          570       580
                   ....*....|....*....|....*...
gi 1753147357 2089 HQEETNQLYKKIAEKEDDLQRTAKRYEE 2116
Cdd:PRK02224   689 ELEELEELRERREALENRVEALEALYDE 716
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 400-494 1.05e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 47.77  E-value: 1.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  400 TQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGE-------ELREQKEKSEKAAFE--EL 470
Cdd:COG0542    411 EELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEaekelieEIQELKEELEQRYGKipEL 490

                           90       100
                   ....*....|....*....|....*
gi 1753147357  471 EKALSTAQKAEESWRKM-KAEVDEQ 494
Cdd:COG0542    491 EKELAELEEELAELAPLlREEVTEE 515
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 787-1404 1.12e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  787 QQVESIIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQ----ASAKLALFQSQQST 862
Cdd:pfam12128  247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGelsaADAAVAKDRSELEA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  863 THEQAKASE----EHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKI--------QVRDLLQQLENQKSEM 930
Cdd:pfam12128  327 LEDQHGAFLdadiETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSkikeqnnrDIAGIKDKLAKIREAR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  931 EEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVI------LQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKN 1004
Cdd:pfam12128  407 DRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLksrlgeLKLRLNQATATPELLLQLENFDERIERAREEQEAANAE 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1005 QEKkmekikqkakemqetlkkkLLDQEAKLKKELENTVLELSQKEKQFNAKILEMAQANSAGISDAVSRLETNQKEQI-- 1082
Cdd:pfam12128  487 VER-------------------LQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPdw 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1083 -ESLTEVHRREL---SDVVSVWEKRLNQQAEELqeqHEIQLQEKEQEVAElkqkilrSACEKEEMNRELAWLKEEGVKQN 1158
Cdd:pfam12128  548 eQSIGKVISPELlhrTDLDPEVWDGSVGGELNL---YGVKLDLKRIDVPE-------WAASEEELRERLDKAEEALQSAR 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1159 TAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERmVELEMLAEKDK-----------LKVFEL 1227
Cdd:pfam12128  618 EKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDK-KNKALAERKDSanerlnsleaqLKQLDK 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1228 TDKLKTTDAQFQSLQSSHERNEKSLE---DKSLEFKKLSEELAVQLEIYSKKTEALLQAKTNEL-------INIS--SNK 1295
Cdd:pfam12128  697 KHQAWLEEQKEQKREARTEKQAYWQVvegALDAQLALLKAAIAARRSGAKAELKALETWYKRDLaslgvdpDVIAklKRE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1296 INAILARISHC-------------QNHTTKVKEALVIKTC-----KASELEAQLRQLTEEQNTLNSSFQQATRQLEEKEN 1357
Cdd:pfam12128  777 IRTLERKIERIavrrqevlryfdwYQETWLQRRPRLATQLsnierAISELQQQLARLIADTKLRRAKLEMERKASEKQQV 856

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 1753147357 1358 QIKSMKADIEgLVMEKEALQREGGNQQQAASEKESCITQLKKELSEN 1404
Cdd:pfam12128  857 RLSENLRGLR-CEMSKLATLKEDANSEQAQGSIGERLAQLEDLKLKR 902
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 754-1303 1.17e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 1.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  754 NKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEINQLGLLLKEKD-KHLKEQQAHV 832
Cdd:TIGR04523  120 NKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNiDKIKNKLLKL 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  833 ENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTH 912
Cdd:TIGR04523  200 ELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  913 KIQVRDLLQQLENQKSEME----EKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMREgqskEIETLKQKLSAKE 988
Cdd:TIGR04523  280 NKKIKELEKQLNQLKSEISdlnnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNE----QISQLKKELTNSE 355

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  989 DSFSVLHEEYEIKfKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKK-ELENTVLELSQKEKQFNAKILEMAQANsagi 1067
Cdd:TIGR04523  356 SENSEKQRELEEK-QNEIEKLKKENQSYKQEIKNLESQINDLESKIQNqEKLNQQKDEQIKKLQQEKELLEKEIER---- 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1068 sdaVSRLETNQKEQIESLTEvhrrelsdVVSVWEKRLNqQAEELQEQHEIQLQEKEQEVAELKQKILRSACEKEEMNREL 1147
Cdd:TIGR04523  431 ---LKETIIKNNSEIKDLTN--------QDSVKELIIK-NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL 498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1148 AWLKEEGVKQNTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELEMLAEKDKLKvfEL 1227
Cdd:TIGR04523  499 KKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELK--QT 576

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1753147357 1228 TDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAKTNelINISSNKINAILARI 1303
Cdd:TIGR04523  577 QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN--IKSKKNKLKQEVKQI 650
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
354-548 1.21e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  354 ETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTklITQLRDAKNLIEQLEQDKgmviaetkrqmHETLEM 433
Cdd:PRK02224   468 ETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR--IERLEERREDLEELIAER-----------RETIEE 534

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  434 KEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKaeeswrkmKAEVDEQIKAIEKTRE--EERTSLQL 511
Cdd:PRK02224   535 KRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK--------LAELKERIESLERIRTllAAIADAED 606

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1753147357  512 ELSRVKQEAVDVMKKSSEQIVKLQKLHE--EELASKEQE 548
Cdd:PRK02224   607 EIERLREKREALAELNDERRERLAEKRErkRELEAEFDE 645
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 609-983 1.27e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.37  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  609 RDLQQEAETYRTRILELE---SSLEKSLQESKNQSEDLAIHLEAEKNKH---NKEITIMVEKHKTELESLQHQQDTLwtE 682
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKrelSSLQSELRRIENRLDELSQELSDASRKIgeiEKEIEQLEQEEEKLKERLEELEEDL--S 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  683 KLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLfqAHIEEM-NEKTFEKLDVKQTELESLSSELSDILKARNKLEEELS 761
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEAL--NDLEARlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLT 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  762 VLKDQADKVKQELEAKLDEqkshhqqqvesiIKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKR 841
Cdd:TIGR02169  826 LEKEYLEKEIQELQEQRID------------LKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  842 SEEELQQAsaklalfQSQQSTTHEQAKASEEHLAQLQQKLLDLETErilLTEQVAEVETQKKDVCTELDTHKIQVRdlLQ 921
Cdd:TIGR02169  894 LEAQLREL-------ERKIEELEAQIEKKRKRLSELKAKLEALEEE---LSEIEDPKGEDEEIPEEELSLEDVQAE--LQ 961

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1753147357  922 QLENQKSEMEEKLQALTQRYESQLRDTNteQAQTKQNLIEKENVILQMRegqSKEIETLKQK 983
Cdd:TIGR02169  962 RVEEEIRALEPVNMLAIQEYEEVLKRLD--ELKEKRAKLEEERKAILER---IEEYEKKKRE 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1995-2200 1.52e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 1.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1995 QKLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHN--STLKQLMREFHTQLAQKDQELEMTIK 2072
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAelEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2073 ETIDKAQDVEAElleshQEETNQLYKKIAEKEDDLQRTAKRYEEiLDAREEEMTAKVMDLQTQLEELQNKYQERLQQEEs 2152
Cdd:COG1196    296 ELARLEQDIARL-----EERRRELEERLEELEEELAELEEELEE-LEEELEELEEELEEAEEELEEAEAELAEAEEALL- 368

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1753147357 2153 pgNDKITIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2200
Cdd:COG1196    369 --EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414
PRK11281 PRK11281
mechanosensitive channel MscK;
1512-1750 1.52e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.21  E-value: 1.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1512 TNKELQMQLELKTK----EVSEKA-----EQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETeLKTQTARIV- 1581
Cdd:PRK11281    37 TEADVQAQLDALNKqkllEAEDKLvqqdlEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEA-LKDDNDEETr 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1582 ---------ELQEHLTQKITEIESLNEALNKYN-----QQKDTE--QKEMLQKLQHIQE----LGEEKDNRVKEAEEKVS 1641
Cdd:PRK11281   116 etlstlslrQLESRLAQTLDQLQNAQNDLAEYNsqlvsLQTQPEraQAALYANSQRLQQirnlLKGGKVGGKALRPSQRV 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1642 RLEKQVSSMKSELETKKKELEhANSGM----KGKEEELKALEDRLELE--------SAAKLAELKKKAEQKIAAIKKQ-- 1707
Cdd:PRK11281   196 LLQAEQALLNAQNDLQRKSLE-GNTQLqdllQKQRDYLTARIQRLEHQlqllqeaiNSKRLTLSEKTVQEAQSQDEAAri 274

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1753147357 1708 ----LLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQS 1750
Cdd:PRK11281   275 qanpLVAQELEINLQLSQRLLKATEKLNTLTQQNLRVKNWLDRLTQS 321
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1514-1730 1.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1514 KELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVclkgEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITE 1593
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIA----ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1594 IESLNEALNKYNQQ---------KDTEQKEMLQKL-----QHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKK 1659
Cdd:COG4942    106 LAELLRALYRLGRQpplalllspEDFLDAVRRLQYlkylaPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 1660 ELEHANSGMKGKEEELKALEDRLElESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGEL 1730
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELA-ELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 192-713 1.96e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 1.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  192 EQLIQLLRRMERRLNSYKGKCSEFVIAYQTLQREKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEfDASLEE 271
Cdd:COG1196    249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL-EEELAE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  272 KDQHISVLQTQVSLLKQRLRngpmnvdlpkpfpQMEPQAEGVSKENTDGDIEPVVVDGASAKTLEVLQQRVKRQENLLQR 351
Cdd:COG1196    328 LEEELEELEEELEELEEELE-------------EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  352 ---CKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMH 428
Cdd:COG1196    395 aaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  429 ETLEM--KEEEIAQLRSRiKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAE-----------VDEQI 495
Cdd:COG1196    475 LEAALaeLLEELAEAAAR-LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEaaleaalaaalQNIVV 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  496 KAIEKTREEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEE----LASKEQELTKKFQTQERQFQEQMKIALEKS 571
Cdd:COG1196    554 EDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAavdlVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  572 QSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEK 651
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1753147357  652 NKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDK 713
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
800-1004 2.17e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 2.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  800 IQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQstTHEQAKASEEHLAQLQQ 879
Cdd:COG4913    615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEA--ELERLDASSDDLAALEE 692

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  880 KLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLEN-QKSEMEEKLQALTQRYESQLRDTNTEqaqtkqn 958
Cdd:COG4913    693 QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERFAAALGDAVER------- 765

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1753147357  959 liekenvilQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKN 1004
Cdd:COG4913    766 ---------ELRENLEERIDALRARLNRAEEELERAMRAFNREWPA 802
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
800-1123 2.24e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 46.05  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  800 IQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQ 879
Cdd:COG4372     43 LQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQK 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  880 KLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNL 959
Cdd:COG4372    123 ERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEEL 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  960 IEKENVILQMREGQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELE 1039
Cdd:COG4372    203 AEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAA 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1040 NTVLELSQKEKQFNAKILEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEELQEQHEIQL 1119
Cdd:COG4372    283 LELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKG 362


                   ....
gi 1753147357 1120 QEKE 1123
Cdd:COG4372    363 AEAG 366
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
818-1214 2.40e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 2.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  818 LKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQsQQSTTHEQAKASEEHLAQLQQklldLETERILLTEQVAE 897
Cdd:COG4717     76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELR-EELEKLEKLLQLLPLYQELEA----LEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  898 VETQKKdvctELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMREgqskEI 977
Cdd:COG4717    151 LEERLE----ELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQE----EL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  978 ETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNAKIL 1057
Cdd:COG4717    223 EELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1058 EMAQANSAGISDAVSRLE-TNQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVAELKQKIlrs 1136
Cdd:COG4717    303 EAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEA--- 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1137 ACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQ--SAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELE 1214
Cdd:COG4717    380 GVEDEEELRAALEQAEEYQELKEELEELEEQLEELlgELEELLEALDEEELEEELEELEEELEELEEELEELREELAELE 459
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 800-940 2.51e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.92  E-value: 2.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  800 IQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQST--THEQAKASEEHLAQL 877
Cdd:COG1579     22 LEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIESL 101

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1753147357  878 QQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQR 940
Cdd:COG1579    102 KRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 374-944 2.95e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 2.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  374 QEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVIA------ETKRQMHETLEMKEEEIAQLRSRIKQ 447
Cdd:pfam01576   21 QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAArkqeleEILHELESRLEEEEERSQQLQNEKKK 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  448 MTAQGEELREQKEKSEKAAFE-ELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSlqlelsrvkqEAVDVMKK 526
Cdd:pfam01576  101 MQQHIQDLEEQLDEEEAARQKlQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERIS----------EFTSNLAE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  527 SSEQIVKLQKL-HEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLAleelelqkKAILMESE 605
Cdd:pfam01576  171 EEEKAKSLSKLkNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAEL--------RAQLAKKE 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  606 NKLRDLQQEAETYRTRilelESSLEKSLQESKNQSEDLAIHLEAEKNKHNKeitimVEKHK----TELESLQHQ-QDTLW 680
Cdd:pfam01576  243 EELQAALARLEEETAQ----KNNALKKIRELEAQISELQEDLESERAARNK-----AEKQRrdlgEELEALKTElEDTLD 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  681 TEKLQvlkqehqtemEKLREKHEQEKETL---LKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARNKLE 757
Cdd:pfam01576  314 TTAAQ----------QELRSKREQEVTELkkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALE 383

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  758 EELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKdeinqlglllkekdkhLKEQQAHVENLEA 837
Cdd:pfam01576  384 SENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEK----------------LSKLQSELESVSS 447

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  838 DIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVCTELDTHKIQVR 917
Cdd:pfam01576  448 LLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLS 527

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1753147357  918 DL----------LQQLENQKSEMEEKLQALTQRYESQ 944
Cdd:pfam01576  528 DMkkkleedagtLEALEEGKKRLQRELEALTQQLEEK 564
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1513-1839 2.99e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 2.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1513 NKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKE-----CNLETELKTQTARIVELQEHL 1587
Cdd:COG4717     69 NLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEkllqlLPLYQELEALEAELAELPERL 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1588 TQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSG 1667
Cdd:COG4717    149 EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1668 MKGKEEELKALEDR----------------LELESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGELN 1731
Cdd:COG4717    229 LEQLENELEAAALEerlkearlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1732 TKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQEEaglqgcvQKAYEDKVSALQRSLMEKEKLLQRLEQ 1811
Cdd:COG4717    309 ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR-------EAEELEEELQLEELEQEIAALLAEAGV 381

                          330       340
                   ....*....|....*....|....*...
gi 1753147357 1812 EKEEMVSSHSEMQGRYQELLIKIEHAEA 1839
Cdd:COG4717    382 EDEEELRAALEQAEEYQELKEELEELEE 409
46 PHA02562
endonuclease subunit; Provisional
 1449-1696 3.06e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.78  E-value: 3.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1449 ISSLSKRYEEQQRELLGQVQDLSLKVETLsKEKVSALEQ-VDHLSNKFSEWKKKAQSKFIQYHSTNKELQMQLELKTKEV 1527
Cdd:PHA02562   165 LSEMDKLNKDKIRELNQQIQTLDMKIDHI-QQQIKTYNKnIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDEL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1528 SEKAEQIHSLKENLDQQNERLVCLKGEME--DKKSKLEKK--ECNLETE-LKTQTARIVELQEHLTQKITEIESLNEALN 1602
Cdd:PHA02562   244 LNLVMDIEDPSAALNKLNTAAAKIKSKIEqfQKVIKMYEKggVCPTCTQqISEGPDRITKIKDKLKELQHSLEKLDTAID 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1603 KYNQQKDteqkeMLQKLQhiqelgeekdNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRL 1682
Cdd:PHA02562   324 ELEEIMD-----EFNEQS----------KKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDEL 388

                          250
                   ....*....|....
gi 1753147357 1683 ElESAAKLAELKKK 1696
Cdd:PHA02562   389 D-KIVKTKSELVKE 401
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1235-2093 3.21e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.12  E-value: 3.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1235 DAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEALLQAKTNELINISSNKINAILARISHCQNHTTKVK 1314
Cdd:pfam02463  185 LAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1315 EALVIKTCKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCI 1394
Cdd:pfam02463  265 EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1395 TQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQNSISLTEKEAAISSLSKRYEEQQRELLGQVQDLSLKV 1474
Cdd:pfam02463  345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1475 ETLSKEKVSALEQVDHLSNKFSEWKKKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGE 1554
Cdd:pfam02463  425 KKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESK 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1555 MEDKKSKLE-----KKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQ----KLQHIQEL 1625
Cdd:pfam02463  505 ARSGLKVLLalikdGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTElplgARKLRLLI 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1626 GEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLEL---------ESAAKLAELKKK 1696
Cdd:pfam02463  585 PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAkesglrkgvSLEEGLAEKSEV 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1697 AEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQE 1776
Cdd:pfam02463  665 KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQK 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1777 EAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINHLQKELE 1856
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1857 EKSKNYSLIASQHVEEEGGKNNIGAKQNLENVVDDVQKTLQEKELACQILEQKIKELDSCLVREREGHRVEMEELTSKFE 1936
Cdd:pfam02463  825 EQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEE 904

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1937 KLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGkeivklqkdlrmLRKEHQ 2016
Cdd:pfam02463  905 ESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL------------LAKEEL 972

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1753147357 2017 QELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAELLESHQEET 2093
Cdd:pfam02463  973 GKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAELR 1049
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1345-1941 3.40e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 3.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1345 FQQATRQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISS 1424
Cdd:PRK03918   160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1425 LSKQLTDLNTQLQNSISLTEKEAAISSLSKRYEEQQRELLGQVQDL------SLKVETLSKEKVSALEQVDHLSNKFSEW 1498
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkelkekAEEYIKLSEFYEEYLDELREIEKRLSRL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1499 KKKAQS--KFIQYHSTNKELQMQLELKTKEVSEKA----------EQIHSLKENLDQQNERLVCL-KGEMEDKKSKLEKK 1565
Cdd:PRK03918   320 EEEINGieERIKELEEKEERLEELKKKLKELEKRLeeleerhelyEEAKAKKEELERLKKRLTGLtPEKLEKELEELEKA 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1566 ECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEmlqklqHIQELGEEKDNRVKEAEEKVSRLEK 1645
Cdd:PRK03918   400 KEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEE------HRKELLEEYTAELKRIEKELKEIEE 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1646 QVSSMKSELETKKKELEHANSGMKGKE--EELKALEDRLE---LESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQqyk 1720
Cdd:PRK03918   474 KERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKkynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK--- 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1721 kdteghLGELNTKLQEKEREIQVLEEKLQSVEGppqseasavpRSAEHMAACAEQEEAGLQGcVQKAYEDKVSAL--QRS 1798
Cdd:PRK03918   551 ------LEELKKKLAELEKKLDELEEELAELLK----------ELEELGFESVEELEERLKE-LEPFYNEYLELKdaEKE 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1799 LMEKEKLLQRLEQEKEEMVSSHSEMQGRYQELLIKIEHAEAKQHEDQimINHLQKELEEKSKNYSLIASQhveeeggknn 1878
Cdd:PRK03918   614 LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE--YEELREEYLELSRELAGLRAE---------- 681

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1753147357 1879 igaKQNLENVVDDVQKTLQEKELACQILEQKIKELDSClvrerEGHRVEMEELTSKFEKLQAL 1941
Cdd:PRK03918   682 ---LEELEKRREEIKKTLEKLKEELEEREKAKKELEKL-----EKALERVEELREKVKKYKAL 736
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1383-1615 3.43e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1383 QQQAASEKESCITQLKKELSENINAVTLMKEELKEKKSEISSLSKQLTDLNTQLQN-SISLTEKEAAISSLSKRYEEQQR 1461
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAlEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1462 ELLGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEwkkkAQSKFIQYHSTNKELQMQLElktkEVSEKAEQIHSLKENL 1541
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLD----AVRRLQYLKYLAPARREQAE----ELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1753147357 1542 DQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEM 1615
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
PRK12704 PRK12704
phosphodiesterase; Provisional
 1521-1711 4.26e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 4.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1521 ELKTKEVSEKAEQI--HSLKENLDQQNERLVCLKGEMEDKKSKLEKkecnletELKTQTARIVELQEHLTQKITEIESLN 1598
Cdd:PRK12704    30 EAKIKEAEEEAKRIleEAKKEAEAIKKEALLEAKEEIHKLRNEFEK-------ELRERRNELQKLEKRLLQKEENLDRKL 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1599 EALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKvsrLEKqVSSMKSEletkkkelehansgmKGKEEELKAL 1678
Cdd:PRK12704   103 ELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQE---LER-ISGLTAE---------------EAKEILLEKV 163

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1753147357 1679 EDRLELESAAKLAELKKKAEQKIAAIKKQLLSQ 1711
Cdd:PRK12704   164 EEEARHEAAVLIKEIEEEAKEEADKKAKEILAQ 196
mukB PRK04863
chromosome partition protein MukB;
192-458 4.74e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 4.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  192 EQLIQLLRR----MERRLNSYKGKCSEFVIAYQTLQREKKKLQGILSQS----QDKALRRIGELREELQMDQQAKKHLQ- 262
Cdd:PRK04863   836 EAELRQLNRrrveLERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllaDETLADRVEEIREQLDEAEEAKRFVQq 915

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  263 --------EEFDASLEEKDQHISVLQTQVSLLKQRLRNGPMNVDLPKPFPQmepQAEGVSKENTDGDIepvvvdGASAKT 334
Cdd:PRK04863   916 hgnalaqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEML------AKNSDL 986

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  335 LEVLQQRVKRQENLLQRCKETIQSHKEQC-------ALLTSEKEALQEQLDERLQELEKM--------KELHMAEKTKLI 399
Cdd:PRK04863   987 NEKLRQRLEQAEQERTRAREQLRQAQAQLaqynqvlASLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELH 1066

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357  400 TQLRDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTAQGEELREQ 458
Cdd:PRK04863  1067 ARLSANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 421-641 6.79e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  421 AETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAfEELEKALSTAQKAEESWRKMKAEVDEQIKAIEK 500
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  501 TREEERTSLQLEL------SRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSE 574
Cdd:COG4942     98 ELEAQKEELAELLralyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1753147357  575 YLKITQEKEQQEslaLEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSE 641
Cdd:COG4942    178 ALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 494-1058 7.04e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.01  E-value: 7.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  494 QIKAIEKT---REEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQtqerqfqeqmkIALEK 570
Cdd:TIGR04523   55 ELKNLDKNlnkDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQ-----------KNKLE 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  571 SQSEYLKITQEKEQQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNqsedlaihLEAE 650
Cdd:TIGR04523  124 VELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDK--------IKNK 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  651 KNKHNKEITIMVEKHKteleslQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQahIEEMNEKTFE 730
Cdd:TIGR04523  196 LLKLELLLSNLKKKIQ------KNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQ--LKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  731 KLDVKQTELESLSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKE---L 807
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQisqL 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  808 KDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETE 887
Cdd:TIGR04523  348 KKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  888 RILLTEQVAEVETQKKDVCTELDTHKIQVRDllqqLENQKSEMEEKLQALTQRYESqlrdTNTEQAQTKQNLIEKENVIL 967
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIKN----LDNTRESLETQLKVLSRSINK----IKQNLEQKQKELKSKEKELK 499

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  968 QMREgQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKE------LENT 1041
Cdd:TIGR04523  500 KLNE-EKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKeieelkQTQK 578

                          570
                   ....*....|....*..
gi 1753147357 1042 VLELSQKEKQFNAKILE 1058
Cdd:TIGR04523  579 SLKKKQEEKQELIDQKE 595
PRK12704 PRK12704
phosphodiesterase; Provisional
 1686-1860 7.35e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 7.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1686 SAAKLAELKKKAEQKIA-------AIKKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEEKLqsvegppqse 1758
Cdd:PRK12704    29 AEAKIKEAEEEAKRILEeakkeaeAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENL---------- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1759 asavprsaEHMAACAEQEEAGLQgcvqkAYEDKVSALQRSLMEKEKLLQRLEQEKE---EMVSSHSEMQGRyQELLIKIE 1835
Cdd:PRK12704    99 --------DRKLELLEKREEELE-----KKEKELEQKQQELEKKEEELEELIEEQLqelERISGLTAEEAK-EILLEKVE 164

                          170       180
                   ....*....|....*....|....*
gi 1753147357 1836 hAEAKqHEDQIMINHLQKELEEKSK 1860
Cdd:PRK12704   165 -EEAR-HEAAVLIKEIEEEAKEEAD 187
PRK11281 PRK11281
mechanosensitive channel MscK;
666-959 7.68e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.90  E-value: 7.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  666 KTELESLQHQQDTLWTEKL--QVL---------KQEHQTEMEKLREKHEQEKETLLKDKESL--FQAHIEEMNEKTFEKL 732
Cdd:PRK11281    42 QAQLDALNKQKLLEAEDKLvqQDLeqtlalldkIDRQKEETEQLKQQLAQAPAKLRQAQAELeaLKDDNDEETRETLSTL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  733 DVKQteleslsselsdilkarnkLEEELSVLKDQADKVKQELeAKLDEQKSHHQQQVE---SIIKEQEMSIQRTEKELKD 809
Cdd:PRK11281   122 SLRQ-------------------LESRLAQTLDQLQNAQNDL-AEYNSQLVSLQTQPEraqAALYANSQRLQQIRNLLKG 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  810 -EINQLGLLLKEKDKHLKEQQAhvenLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQ----QKLLDL 884
Cdd:PRK11281   182 gKVGGKALRPSQRVLLQAEQAL----LNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQeainSKRLTL 257

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357  885 eTErilltEQVAEVETQKkdvctelDTHKIQVRDLLQQlenqksEMEEKLQaLTQRYESQLRDTNTeqaQTKQNL 959
Cdd:PRK11281   258 -SE-----KTVQEAQSQD-------EAARIQANPLVAQ------ELEINLQ-LSQRLLKATEKLNT---LTQQNL 309
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1457-1692 8.59e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 8.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1457 EEQQRELLGQVQDLSLKVETLsKEKVSALEQVDHLSNKFsewkkKAQSKFiqyhstnKELQMQLELKTKEVSEKAEQIHS 1536
Cdd:COG4913    247 AREQIELLEPIRELAERYAAA-RERLAELEYLRAALRLW-----FAQRRL-------ELLEAELEELRAELARLEAELER 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1537 LKENLDQQNERLVCLKGEMEDkkSKLEKKEcNLETELKTQTARIVELQEHLTQkiteiesLNEALNKYNQQKDTEQKEML 1616
Cdd:COG4913    314 LEARLDALREELDELEAQIRG--NGGDRLE-QLEREIERLERELEERERRRAR-------LEALLAALGLPLPASAEEFA 383

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1753147357 1617 QKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALedRLELESAAKLAE 1692
Cdd:COG4913    384 ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL--RDALAEALGLDE 457
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1578-2146 8.81e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 8.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1578 ARIVELQEHLTQkiteiesLNEAlnkYNQQKDTEQKEMLqkLQHIQELGEekdnRVKEAEEKVSRLEKQVSsmKSELETK 1657
Cdd:COG4913    225 EAADALVEHFDD-------LERA---HEALEDAREQIEL--LEPIRELAE----RYAAARERLAELEYLRA--ALRLWFA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1658 KKELEHANSGMKGKEEELKALEDRLElesaaKLAELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDteghLGELNTKLQEK 1737
Cdd:COG4913    287 QRRLELLEAELEELRAELARLEAELE-----RLEARLDALREELDELEAQIRGNGGDRLEQLERE----IERLERELEER 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1738 EREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQEEAglqgcVQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMV 1817
Cdd:COG4913    358 ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE-----ELEALEEALAEAEAALRDLRRELRELEAEIASLE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1818 SSHSEMQGRYQELLIKIEHAeAKQHEDQIMI--NHLQ-KELEEKSKN----------YSLI--------ASQHVEEEGGK 1876
Cdd:COG4913    433 RRKSNIPARLLALRDALAEA-LGLDEAELPFvgELIEvRPEEERWRGaiervlggfaLTLLvppehyaaALRWVNRLHLR 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1877 NNIGAKQNLENVVDDVQKTLQEKELACQIleqKIKE------LDSCLVREREGHRVEMEELTSKFEKlqALQQQMEGKNK 1950
Cdd:COG4913    512 GRLVYERVRTGLPDPERPRLDPDSLAGKL---DFKPhpfrawLEAELGRRFDYVCVDSPEELRRHPR--AITRAGQVKGN 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1951 PTealeesAEEKSKSHVV--QPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQ--------QELD 2020
Cdd:COG4913    587 GT------RHEKDDRRRIrsRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalqrlaeySWDE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2021 IMKKEYEQEMEEkIKQEQEDLElKHNSTLKQLMREFHtQLAQKDQELEMTIKETIDKAQDVEAELlESHQEETNQLYKKI 2100
Cdd:COG4913    661 IDVASAEREIAE-LEAELERLD-ASSDDLAALEEQLE-ELEAELEELEEELDELKGEIGRLEKEL-EQAEEELDELQDRL 736

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1753147357 2101 AEKED-----------------DLQRTAKRYEEILDAREEEMTAKVMDLQTQLEELQNKYQER 2146
Cdd:COG4913    737 EAAEDlarlelralleerfaaaLGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 363-640 9.69e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 9.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  363 CALLTSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDkgmvIAETKRQMHETlemkEEEIAQLR 442
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRAL----EQELAALE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  443 SRIKQMTAQGEELREQKEKSEkaafEELEKALSTAQKAeeswrkmkaevdeqikaiektreEERTSLQLELSRVKQEAVD 522
Cdd:COG4942     83 AELAELEKEIAELRAELEAQK----EELAELLRALYRL-----------------------GRQPPLALLLSPEDFLDAV 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  523 VMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQfQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAilm 602
Cdd:COG4942    136 RRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-RAELEALLAELEEERAALEALKAERQKLLARLEKELAEL--- 211

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1753147357  603 esENKLRDLQQEAETYRTRILELESSLEKSLQESKNQS 640
Cdd:COG4942    212 --AAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 234-931 1.14e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  234 SQSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQHISVLQTQVSLLKQRLRNgpmnvdlpkpfpqmepqaegv 313
Cdd:pfam12128  250 FNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG--------------------- 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  314 SKENTDGDIEpvvvdgASAKTLEVLQQRVKRqenLLQRCKETIQSHKEQCALLTSEKEALQEQLDERLQELEKMKELHMA 393
Cdd:pfam12128  309 ELSAADAAVA------KDRSELEALEDQHGA---FLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNR 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  394 EKTKLITQLRDAknlIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSrikQMTAQGEELREQKEKSEKAAfEELEKA 473
Cdd:pfam12128  380 RRSKIKEQNNRD---IAGIKDKLAKIREARDRQLAVAEDDLQALESELRE---QLEAGKLEFNEEEYRLKSRL-GELKLR 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  474 LSTAQKAEESWRKMKAEVDEQIKAIEK--TREEERTSLQLELSRVKqeavdvmKKSSEQIVKLQKLHE--EELASKEQEL 549
Cdd:pfam12128  453 LNQATATPELLLQLENFDERIERAREEqeAANAEVERLQSELRQAR-------KRRDQASEALRQASRrlEERQSALDEL 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  550 TKKFQTQERQFQEQM-KIALEKSQSEYLKITQEKEQQESLALEELELQKKAILMESENKLR-------DLQQEAETYRTR 621
Cdd:pfam12128  526 ELQLFPQAGTLLHFLrKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDlkridvpEWAASEEELRER 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  622 ILELESSLEKSLQESKNQSEDLAiHLEAEKNKHNKEITIMVEKHKTELESLQHQQDTLWTEKLQVLKQ--EHQTEMEKLR 699
Cdd:pfam12128  606 LDKAEEALQSAREKQAAAEEQLV-QANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKAlaERKDSANERL 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  700 EKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDvkqteleslsselsdilkarnKLEEELSVLKDQADKVKQELEAKLD 779
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQA---------------------YWQVVEGALDAQLALLKAAIAARRS 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  780 EQKSHhqqqvesiikeqemsIQRTEKELKDEINQLGlLLKEKDKHLKEQqahVENLEADIKRSEeelQQASAKLALFQSQ 859
Cdd:pfam12128  744 GAKAE---------------LKALETWYKRDLASLG-VDPDVIAKLKRE---IRTLERKIERIA---VRRQEVLRYFDWY 801

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1753147357  860 QSTTHEQAKASEEHLAQLQQKLLDLETErilLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENQKSEME 931
Cdd:pfam12128  802 QETWLQRRPRLATQLSNIERAISELQQQ---LARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMS 870
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1445-1965 1.17e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.04  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1445 KEAAISSLskryEEQQRELLGQVQDLSLKVETLSKEKVSALEQV-------DHLSNKFSEWKKKAQSKfiqyHSTNKELQ 1517
Cdd:pfam10174  238 KDTKISSL----ERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMevykshsKFMKNKIDQLKQELSKK----ESELLALQ 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1518 MQLELKTKEVSEKAEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKecnlETELKTQTARIVELQEHLTQKITEIESL 1597
Cdd:pfam10174  310 TKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK----ESFLNKKTKQLQDLTEEKSTLAGEIRDL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1598 NEALNKYNQQKDTEQKemlqKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEElKA 1677
Cdd:pfam10174  386 KDMLDVKERKINVLQK----KIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQ-RE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1678 LEDRLELESAAKLAELKKKAEQKIAAIKKQLLSQmeekeQQYKKDTEGHLGELNTKLQEKEREIQVLEEKL-QSVEGPPQ 1756
Cdd:pfam10174  461 REDRERLEELESLKKENKDLKEKVSALQPELTEK-----ESSLIDLKEHASSLASSGLKKDSKLKSLEIAVeQKKEECSK 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1757 SEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQgryqelliKIEH 1836
Cdd:pfam10174  536 LENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIA--------ELES 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1837 AEAKQHEDQIM--INHLQKELEEKSKNYSLIASQHVEEEGGKNNiGAKQNLENVVDDVQKTLQEKELACQIL---EQKIK 1911
Cdd:pfam10174  608 LTLRQMKEQNKkvANIKHGQQEMKKKGAQLLEEARRREDNLADN-SQQLQLEELMGALEKTRQELDATKARLsstQQSLA 686

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1753147357 1912 ELDSCLVREREGHRVEMEELTSKfeKLQALQQQMEGKNKPTEALEESAEEKSKS 1965
Cdd:pfam10174  687 EKDGHLTNLRAERRKQLEEILEM--KQEALLAAISEKDANIALLELSSSKKKKT 738
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 780-988 1.18e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  780 EQKSHHQQQVESIIKEqemsIQRTEKELKDEINQLGLLLKEkdkhLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQ 859
Cdd:COG4942     20 DAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQ----LAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  860 QSTTHEQAKASEEHLAQL---QQKLLDLETERILLTEQ-----------VAEVETQKKDVCTELDTHKIQVRDLLQQLEN 925
Cdd:COG4942     92 IAELRAELEAQKEELAELlraLYRLGRQPPLALLLSPEdfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1753147357  926 QKSEMEEKLQALTQ---RYESQLRDTNTEQAQTKQNLIEKENVILQMREgQSKEIETLKQKLSAKE 988
Cdd:COG4942    172 ERAELEALLAELEEeraALEALKAERQKLLARLEKELAELAAELAELQQ-EAEELEALIARLEAEA 236
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
832-1040 1.39e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  832 VENLEaDIKRSEEELQQASAKLALFQ--SQQSTTHEQAKASEEHLAQL---------QQKLLDLETERILLTEQVAEVET 900
Cdd:COG4913    231 VEHFD-DLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLraalrlwfaQRRLELLEAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  901 QKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQAltqryesQLRDTNTEQAQTKQNliekenvilqmREGQSKEIETL 980
Cdd:COG4913    310 ELERLEARLDALREELDELEAQIRGNGGDRLEQLER-------EIERLERELEERERR-----------RARLEALLAAL 371

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  981 KQKLSAKEDSFSVLHEEYEiKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEAKLKKELEN 1040
Cdd:COG4913    372 GLPLPASAEEFAALRAEAA-ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 603-854 1.41e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  603 ESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAiHLEAEKNKHNKEItimvEKHKTELESLQHQQDTLwTE 682
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIA-ALARRIRALEQEL----AALEAELAELEKEIAEL-RA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  683 KLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAhieemnektfekldvkqtelESLSSELSDILKARNKLEEELSV 762
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDA--------------------VRRLQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  763 LKDQADKVKQELEAKLDEQKSHHQQQvesiiKEQEMSIQRTEKELKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRS 842
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAEL-----EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232

                          250
                   ....*....|..
gi 1753147357  843 EEELQQASAKLA 854
Cdd:COG4942    233 EAEAAAAAERTP 244
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 756-982 1.46e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.17  E-value: 1.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  756 LEEELSVLKDQADKVKQ---ELEAKLDEQKSHHQQQ------VESIIKEQEMS--IQRTEKELKDEINQlglllkekdKH 824
Cdd:COG3096    439 AEDYLAAFRAKEQQATEevlELEQKLSVADAARRQFekayelVCKIAGEVERSqaWQTARELLRRYRSQ---------QA 509

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  825 LKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKD 904
Cdd:COG3096    510 LAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQ 589

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  905 VCTELDTHK------IQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDtNTEQAQTKQNLIEKENVILQmregqskEIE 978
Cdd:COG3096    590 LRARIKELAarapawLAAQDALERLREQSGEALADSQEVTAAMQQLLER-EREATVERDELAARKQALES-------QIE 661


                   ....
gi 1753147357  979 TLKQ 982
Cdd:COG3096    662 RLSQ 665
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1986-2200 1.47e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1986 KLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQQELDIMKkeyeqEMEEKIKQEQEDLelkhnSTLKQLMREFHTQLAQKDQ 2065
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-----ALERRIAALARRI-----RALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2066 ELEmTIKETIDKAQDVEAELLESHQEETNQLYKKI---AEKEDDLQRTAKRYEEILDAREEEMTAKVMDLQTQLEELQNK 2142
Cdd:COG4942     91 EIA-ELRAELEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1753147357 2143 YQERLQQEESPGNDKITIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2200
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
PLN02939 PLN02939
transferase, transferring glycosyl groups
 778-1042 1.47e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.12  E-value: 1.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  778 LDEQKSHHQQQVESIIKEQEmsiqrtekELKDEINQLGLLLKEKDKHLK---EQQAHVENLEADIKRSEEELQQASA--- 851
Cdd:PLN02939   147 LNQARLQALEDLEKILTEKE--------ALQGKINILEMRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGAteg 218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  852 --------KLALFQSQQSTTHEQA---KASEEHLAQLQQKLLDLETERILLTEQVAEVETQ----KKDVcTELDTHKIQV 916
Cdd:PLN02939   219 lcvhslskELDVLKEENMLLKDDIqflKAELIEVAETEERVFKLEKERSLLDASLRELESKfivaQEDV-SKLSPLQYDC 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  917 R----DLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENvilqmregqSKEIETLKQKLSAKEDSFS 992
Cdd:PLN02939   298 WwekvENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVSKFS---------SYKVELLQQKLKLLEERLQ 368

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1753147357  993 VLHEEYeikfknqEKKMEKIKQKAKEMQETLKKklLDQEAKlKKELENTV 1042
Cdd:PLN02939   369 ASDHEI-------HSYIQLYQESIKEFQDTLSK--LKEESK-KRSLEHPA 408
46 PHA02562
endonuclease subunit; Provisional
 1206-1406 1.49e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.85  E-value: 1.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1206 LQERMVELEMLAEKDKL---KVFELTDKLKTTDAQFQSLQS---SHERNEKSLEDKSLEFKKLSEELAVQLEIYSKKTEA 1279
Cdd:PHA02562   155 LVEDLLDISVLSEMDKLnkdKIRELNQQIQTLDMKIDHIQQqikTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1280 LLQAKTNELINISS---------NKINAILARISHCQNHTTKV----KEALVIKTC----------------KASELEAQ 1330
Cdd:PHA02562   235 EIEELTDELLNLVMdiedpsaalNKLNTAAAKIKSKIEQFQKVikmyEKGGVCPTCtqqisegpdritkikdKLKELQHS 314

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 1331 LRQLTEEQNTLNS---SFQQATRQLEEKENQIKSMKADIEGLVMEKEALQREGGNQQQAASEKESCITQLKKELSENIN 1406
Cdd:PHA02562   315 LEKLDTAIDELEEimdEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK 393
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
218-458 1.60e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  218 AYQTLQREKKKLQGILSQSQD-KALRRIGELREELQMDQQAKKHLQEEfdasLEEKDQHISVLQTQVSLLKQRLRngpmn 296
Cdd:COG4913    263 RYAAARERLAELEYLRAALRLwFAQRRLELLEAELEELRAELARLEAE----LERLEARLDALREELDELEAQIR----- 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  297 vdlpkpfpqmepqaegvskentdgdiepvvvdGASAKTLEVLQQRVKRQENLLQRCKETIQSHKEQCALL-----TSEKE 371
Cdd:COG4913    334 --------------------------------GNGGDRLEQLEREIERLERELEERERRRARLEALLAALglplpASAEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  372 --ALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQdkgmviaetkrqmhetlemkeeEIAQLRSRIKQMT 449
Cdd:COG4913    382 faALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA----------------------EIASLERRKSNIP 439


                   ....*....
gi 1753147357  450 AQGEELREQ 458
Cdd:COG4913    440 ARLLALRDA 448
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
408-549 1.61e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.69  E-value: 1.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  408 LIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAfEELEKALSTAQKAEESWRKM 487
Cdd:COG2433    385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERI-ERLERELSEARSEERREIRK 463

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1753147357  488 KAEV---DEQIKAIEKTREEERT---SLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQEL 549
Cdd:COG2433    464 DREIsrlDREIERLERELEEERErieELKRKLERLKELWKLEHSGELVPVKVVEKFTKEAIRRLEEEY 531
COG5022 COG5022
Myosin heavy chain [General function prediction only];
344-970 1.65e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.91  E-value: 1.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  344 RQENLLQRCKETIQSHKEQCALltsEKEALQEQLDERLQELEK-MKELHMAEKTklITQLrdaKNLIEQLEQDKGMVIAE 422
Cdd:COG5022    843 KAEVLIQKFGRSLKAKKRFSLL---KKETIYLQSAQRVELAERqLQELKIDVKS--ISSL---KLVNLELESEIIELKKS 914

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  423 TKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKAL-STAQKAEESWRKMKAEVDEQIKAIEKT 501
Cdd:COG5022    915 LSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLkETSEEYEDLLKKSTILVREGNKANSEL 994

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  502 R---------EEERTSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQ 572
Cdd:COG5022    995 KnfkkelaelSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRE 1074

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  573 SEYLKITQEKEQQESLALEELELQKKA-----ILMESENKLR--DLQQEAETYRTRILELESSLEKSLQESKNQSEDLAI 645
Cdd:COG5022   1075 NSLLDDKQLYQLESTENLLKTINVKDLevtnrNLVKPANVLQfiVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQL 1154

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  646 HLEAEKNKHNKEitimvEKHKTELESLQHQ----QDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLfQAHI 721
Cdd:COG5022   1155 ELDGLFWEANLE-----ALPSPPPFAALSEkrlyQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLK-KLIS 1228

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  722 EEMNEKTFekldvKQTELESLSSELSDILKARNKLEEELSVLK-DQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSI 800
Cdd:COG5022   1229 EGWVPTEY-----STSLKGFNNLNKKFDTPASMSNEKLLSLLNsIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRT 1303

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  801 QRTEKELK--DEINQLGLLLKEKDKhlkeqqahvenlEADIKRSEEELQQasaklaLFQSQQSTTHEQAKASE-EHLAQL 877
Cdd:COG5022   1304 KASSLRWKsaTEVNYNSEELDDWCR------------EFEISDVDEELEE------LIQAVKVLQLLKDDLNKlDELLDA 1365

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  878 QQKLLDLETERILLTEQVAEVETQ-KKDVCTELDThkiQVRDLLQQLENQ-KSEMEEKLQALTQRYESQLRDTN-----T 950
Cdd:COG5022   1366 CYSLNPAEIQNLKSRYDPADKENNlPKEILKKIEA---LLIKQELQLSLEgKDETEVHLSEIFSEEKSLISLDRnsiykE 1442

                          650       660
                   ....*....|....*....|
gi 1753147357  951 EQAQTKQNLIEKENVILQMR 970
Cdd:COG5022   1443 EVLSSLSALLTKEKIALLDR 1462
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 1990-2172 1.80e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 43.41  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1990 AEQEKQKLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQEME---EKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQE 2066
Cdd:pfam07902  134 ATRISEDTDKKLALINETISGIRREYQDADRQLSSSYQAGIEglkATMASDKIGLQAEIQASAQGLSQRYDNEIRKLSAK 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2067 LEMTIKETID----KAQDVEAELLESHQEETNQLYKKIAEKEDDLQRTAKRYEEILDAREEEMTAKVMDLQTQLEELQNK 2142
Cdd:pfam07902  214 ITTTSSGTTEayesKLDDLRAEFTRSNQGMRTELESKISGLQSTQQSTAYQISQEISNREGAVSRVQQDLDSYQRRLQDA 293

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1753147357 2143 YQ---------ERLQQEESPGNDKIT--IMELQTQLAQKTT 2172
Cdd:pfam07902  294 EKnyssltqtvKGLQSTVSDPNSKLEsrITQLAGLIEQKVT 334
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1541-1711 1.84e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1541 LDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKE-MLQKL 1619
Cdd:COG1579     15 LDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNkEYEAL 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1620 QHiqelgeekdnRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLELESA---AKLAELKKK 1696
Cdd:COG1579     95 QK----------EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAeleAELEELEAE 164

                          170
                   ....*....|....*
gi 1753147357 1697 AEQKIAAIKKQLLSQ 1711
Cdd:COG1579    165 REELAAKIPPELLAL 179
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1937-2209 1.87e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1937 KLQALQQQMEgknKPTEALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLRKEHQ 2016
Cdd:TIGR02168  201 QLKSLERQAE---KAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2017 qeldimkkeyeqEMEEKIKQEQEDLElkhnsTLKQLMREFHTQLA---QKDQELEMTIKETIDKAQDVEAELLEShQEET 2093
Cdd:TIGR02168  278 ------------ELEEEIEELQKELY-----ALANEISRLEQQKQilrERLANLERQLEELEAQLEELESKLDEL-AEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2094 NQLYKKIAEKEDDLQRTAKRYEEiLDAREEEMTAKVMDLQTQLEELQNKYQERLQQEESpgndkitimeLQTQLAQKTTL 2173
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEE-LEAELEELESRLEELEEQLETLRSKVAQLELQIAS----------LNNEIERLEAR 408

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1753147357 2174 ISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGT 2209
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEEAELKELQAELEE 444
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1583-2044 1.99e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1583 LQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELE 1662
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1663 HAN--SGMKGKEEELKALEDRLE--LESAAKLAELKKKAEQKIAAIkKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKE 1738
Cdd:COG4717    127 LLPlyQELEALEAELAELPERLEelEERLEELRELEEELEELEAEL-AELQEELEELLEQLSLATEEELQDLAEELEELQ 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1739 REIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQEEAGlqgcvQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVS 1818
Cdd:COG4717    206 QRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLK-----EARLLLLIAAALLALLGLGGSLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1819 SHSEMQGRYQELLIKIEHAEAKQHEDQIMINHL----QKELEEKSKNYSLIASQHVEE-EGGKNNIGAKQNLENVVDDVQ 1893
Cdd:COG4717    281 LVLGLLALLFLLLAREKASLGKEAEELQALPALeeleEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1894 KTLQEKELACQIlEQKIKELDSCLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKskshvvqprlp 1973
Cdd:COG4717    361 EELQLEELEQEI-AALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE----------- 428

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 1974 gNMEAEHNDLEFKLAGAEQEKQKLGKEIVKLQKDLRMLrkEHQQELDIMKKEYEQEMEEKIKQEQEDLELK 2044
Cdd:COG4717    429 -ELEEELEELEEELEELEEELEELREELAELEAELEQL--EEDGELAELLQELEELKAELRELAEEWAALK 496
46 PHA02562
endonuclease subunit; Provisional
 908-1156 2.10e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.08  E-value: 2.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  908 ELDTHKIQVRDLLQQLENQK---SEMEEKLQALTQRYESQLrDTNTEQAQTKQNLIEK-----ENVILQMREGQS--KEI 977
Cdd:PHA02562   182 QIQTLDMKIDHIQQQIKTYNkniEEQRKKNGENIARKQNKY-DELVEEAKTIKAEIEEltdelLNLVMDIEDPSAalNKL 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  978 ETLKQKLSAKEDSFSVLHEEYEI---------KFKNQEKKMEKIKQKAKEMQETLkKKLLDQEAKLkKELENTVLELSQK 1048
Cdd:PHA02562   261 NTAAAKIKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSL-EKLDTAIDEL-EEIMDEFNEQSKK 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1049 EKQFNAKIlemaqansagisdavsrletnqkeqiesltEVHRRELSDVVSVwEKRLNQQAEELQEQHEIQLQEKEQEVAE 1128
Cdd:PHA02562   339 LLELKNKI------------------------------STNKQSLITLVDK-AKKVKAAIEELQAEFVDNAEELAKLQDE 387

                          250       260       270
                   ....*....|....*....|....*....|.
gi 1753147357 1129 LKQKIL-RSACEKEEMNRELA--WLKEEGVK 1156
Cdd:PHA02562   388 LDKIVKtKSELVKEKYHRGIVtdLLKDSGIK 418
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1447-1708 2.18e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1447 AAISSLSKRYEEQQRELLGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEWKKKAQskfiqyhstnkELQMQLELKTKE 1526
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR-----------ALEQELAALEAE 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1527 VSEKAEQIHSLKENLDQQNERLVCLKGEMEdKKSKLEKKECNLETELKTQTARIVELqehltqkiteIESLNEALNKYNQ 1606
Cdd:COG4942     85 LAELEKEIAELRAELEAQKEELAELLRALY-RLGRQPPLALLLSPEDFLDAVRRLQY----------LKYLAPARREQAE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1607 QKDTEQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLELES 1686
Cdd:COG4942    154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233

                          250       260
                   ....*....|....*....|..
gi 1753147357 1687 AAKLAELKKKAEQKIAAIKKQL 1708
Cdd:COG4942    234 AEAAAAAERTPAAGFAALKGKL 255
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
526-1051 2.28e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 2.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  526 KSSEQIVKLQKLHEEELASKEQELtKKFQTQERQFQEQmkiaLEKSQSEYLKITQEKEQQESLALEELELQKKaiLMESE 605
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREI-NEISSELPELREE----LEKLEKEVKELEELKEEIEELEKELESLEGS--KRKLE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  606 NKLRDLQQEAETYRTRILELESSLEKSlqESKNQSEDLAIHLEAEKNKHNKEITiMVEKHKTELESLqhqqdtlwteklq 685
Cdd:PRK03918   259 EKIRELEERIEELKKEIEELEEKVKEL--KELKEKAEEYIKLSEFYEEYLDELR-EIEKRLSRLEEE------------- 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  686 vlKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDilKARNKLEEELsvlkD 765
Cdd:PRK03918   323 --INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG--LTPEKLEKEL----E 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  766 QADKVKQELEAKLDEQKShHQQQVESIIKEQEMSIQR---------------TEKELKDEINQLGLLLKEKDKHLKEQQA 830
Cdd:PRK03918   395 ELEKAKEEIEEEISKITA-RIGELKKEIKELKKAIEElkkakgkcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEE 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  831 HVENLEADIKRSEEELQQASAKLALFQ----------SQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQV---AE 897
Cdd:PRK03918   474 KERKLRKELRELEKVLKKESELIKLKElaeqlkeleeKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELeklEE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  898 VETQKKDVCTELDTHKIQVRDLLQQLENQK----SEMEEKLQALTQRYESQLRDTNTEQA-QTKQNLIEKE----NVILQ 968
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELAELLKELEELGfesvEELEERLKELEPFYNEYLELKDAEKElEREEKELKKLeeelDKAFE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  969 MREGQSKEIETLKQKLSAKEDSFSVlhEEYEIKFKNQEKKMEKIKQKAKEMQETlkKKLLDQEAKLKKELENTVLELSQK 1048
Cdd:PRK03918   634 ELAETEKRLEELRKELEELEKKYSE--EEYEELREEYLELSRELAGLRAELEEL--EKRREEIKKTLEKLKEELEEREKA 709


                   ...
gi 1753147357 1049 EKQ 1051
Cdd:PRK03918   710 KKE 712
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 366-1267 2.55e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  366 LTSEKEALQEQLDERLQELEKMKELHMAEK-TKLITQLRDAKNLIEQLEQDKGMVIAETKR--QMHETLEMKEEEIAQLR 442
Cdd:TIGR00606  196 QTQGQKVQEHQMELKYLKQYKEKACEIRDQiTSKEAQLESSREIVKSYENELDPLKNRLKEieHNLSKIMKLDNEIKALK 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  443 SRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREE---ERTSLQLELSRVKQE 519
Cdd:TIGR00606  276 SRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLlnqEKTELLVEQGRLQLQ 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  520 AvdvmKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQ------EKEQQESLALEEL 593
Cdd:TIGR00606  356 A----DRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQlcadlqSKERLKQEQADEI 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  594 ELQKKAILMESENKLRDLQQEAETYRTRILELEsSLEKSLQESKNQSEDLaihLEAEKNKHNKEITIMVEKHKTELESLQ 673
Cdd:TIGR00606  432 RDEKKGLGRTIELKKEILEKKQEELKFVIKELQ-QLEGSSDRILELDQEL---RKAERELSKAEKNSLTETLKKEVKSLQ 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  674 HQQDTLwtekLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLdvkqTELESLSSELSDILKAR 753
Cdd:TIGR00606  508 NEKADL----DRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEL----TSLLGYFPNKKQLEDWL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  754 NKLEEELSVLKDQADKVKQELeAKLDEQKSHHQQQVESiikeqemsiqRTEKELKDEINQLGLLLKEkdkhlkEQQAHVE 833
Cdd:TIGR00606  580 HSKSKEINQTRDRLAKLNKEL-ASLEQNKNHINNELES----------KEEQLSSYEDKLFDVCGSQ------DEESDLE 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  834 NLEADIKRSEEELQQASAKLALFQS--QQSTTHEQA-----KASEEHLAQLQQKLLDLETERILLTEQVAEVETQKKDVC 906
Cdd:TIGR00606  643 RLKEEIEKSSKQRAMLAGATAVYSQfiTQLTDENQSccpvcQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  907 TELDTHKIQV---RDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKENV--------ILQMREGQSK 975
Cdd:TIGR00606  723 KRRDEMLGLApgrQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAkvcltdvtIMERFQMELK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  976 EIETLKQKLSAKEDSFSVLHEEYEIKFKNQEK--KMEKIKQKAKEMQetlkkKLLDQEAKLKKELENTVLELSQKEKQFN 1053
Cdd:TIGR00606  803 DVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqhELDTVVSKIELNR-----KLIQDQQEQIQHLKSKTNELKSEKLQIG 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1054 AKILEMAQANsagisdavSRLETNQKEQIESLTEV-HRRELSDVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVAELKQK 1132
Cdd:TIGR00606  878 TNLQRRQQFE--------EQLVELSTEVQSLIREIkDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK 949

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1133 ILRSACEKEEMNRELAWLKEEGVKQNtavrelQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSlrentSLQERMVE 1212
Cdd:TIGR00606  950 VKNIHGYMKDIENKIQDGKDDYLKQK------ETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ-----KIQERWLQ 1018

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357 1213 LEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELA 1267
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLA 1073
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
360-550 2.64e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  360 KEQCALLTSEKEALQE--QLDERLQELEKMKElhMAEKTKLITQLRDAKNLIEQLEQDkgmviaetkrqmhetLEMKEEE 437
Cdd:COG4913    248 REQIELLEPIRELAERyaAARERLAELEYLRA--ALRLWFAQRRLELLEAELEELRAE---------------LARLEAE 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  438 IAQLRSRIKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEE-------RTSLQ 510
Cdd:COG4913    311 LERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASaeefaalRAEAA 390

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1753147357  511 LELSRVKQEAVDVMKKSSEQIVKLQKLhEEELASKEQELT 550
Cdd:COG4913    391 ALLEALEEELEALEEALAEAEAALRDL-RRELRELEAEIA 429
PRK01156 PRK01156
chromosome segregation protein; Provisional
 807-1362 2.94e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 2.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  807 LKDEINQLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQS---QQSTTHEQAKASEEHLAQLQQKLLD 883
Cdd:PRK01156   188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSalnELSSLEDMKNRYESEIKTAESDLSM 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  884 LETERILLTEQVAEVETQKKDVCTELDTHKIQVRDLLQQLENqKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEKE 963
Cdd:PRK01156   268 ELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIEN-KKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKS 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  964 nvilqmregQSKEIETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQETLKKKLLDQEA--KLKKELENT 1041
Cdd:PRK01156   347 ---------RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAikKELNEINVK 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1042 VLELSQKEKQFNAKILEMAQaNSAGISDAVSRLETNQK----------EQIESLTEVHRRELSDVvsvwEKRLNQQAEEL 1111
Cdd:PRK01156   418 LQDISSKVSSLNQRIRALRE-NLDELSRNMEMLNGQSVcpvcgttlgeEKSNHIINHYNEKKSRL----EEKIREIEIEV 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1112 QEQHEIQLQEKEQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTaVRELQEQLHQQSAQTNSLsqnetklkaQLEK 1191
Cdd:PRK01156   493 KDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINE-LKDKHDKYEEIKNRYKSL---------KLED 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1192 LEGDLNHSLRENTSLQERMVE-LEMLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEF---KKLSEELA 1267
Cdd:PRK01156   563 LDSKRTSWLNALAVISLIDIEtNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLnnkYNEIQENK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1268 VQLEIYSKKTEAlLQAKTNELINISSNKiNAILARISHCQNHTTKVKEALVIKTCKASELEAQLRQLTEEQNTLNSSFQQ 1347
Cdd:PRK01156   643 ILIEKLRGKIDN-YKKQIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRIND 720

                          570
                   ....*....|....*
gi 1753147357 1348 ATRQLEEKENQIKSM 1362
Cdd:PRK01156   721 INETLESMKKIKKAI 735
PRK12704 PRK12704
phosphodiesterase; Provisional
 749-903 3.66e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  749 ILKARNKLEEELSVLKDQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEINQL---GLLLKEKDKHL 825
Cdd:PRK12704    33 IKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLdrkLELLEKREEEL 112

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357  826 KEQQAHVENLEADIKRSEEELQQASAK-LALFQSQQSTTHEQAKasEEHLAQLQQKLLDLETERILLTEQVAEVETQKK 903
Cdd:PRK12704   113 EKKEKELEQKQQELEKKEEELEELIEEqLQELERISGLTAEEAK--EILLEKVEEEARHEAAVLIKEIEEEAKEEADKK 189
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1082-1296 3.83e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 3.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1082 IESLTEVHRRELSDVVsvweKRLNQQAEELQEQheiqLQEKEQEVAELKQK---------ILRSACEKEEMNRELAWLKE 1152
Cdd:COG3206    162 LEQNLELRREEARKAL----EFLEEQLPELRKE----LEEAEAALEEFRQKnglvdlseeAKLLLQQLSELESQLAEARA 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1153 EGVKQNTAVRELQEQLHQQSAQTNSLSQNET--KLKAQLEKLEGDLNHSLRENTSLQERMVEL-EMLAEKDKLKVFELTD 1229
Cdd:COG3206    234 ELAEAEARLAALRAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELSARYTPNHPDVIALrAQIAALRAQLQQEAQR 313

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1753147357 1230 KLKTTDAQFQSLQSSHERNEKSLED----------KSLEFKKLSEELAVQLEIYSKKTEALLQAKTNELINISSNKI 1296
Cdd:COG3206    314 ILASLEAELEALQAREASLQAQLAQlearlaelpeLEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVRV 390
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1592-1794 4.11e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 4.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1592 TEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDN---RVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGM 1668
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNElqaELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1669 KGKEEELKALE------------DRLEL-----ESAAKLAELKKKAEQKIAAIKKQLLSQMEEKEQQyKKDTEGHLGELN 1731
Cdd:COG3883     96 YRSGGSVSYLDvllgsesfsdflDRLSAlskiaDADADLLEELKADKAELEAKKAELEAKLAELEAL-KAELEAAKAELE 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1753147357 1732 TKLQEKEREIQVLEEKLQSVEGPPQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKVSA 1794
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAA 237
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1552-1697 4.54e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.15  E-value: 4.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1552 KGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEmlqklqhiqelgeekdn 1631
Cdd:COG2433    401 KEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRK----------------- 463

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1753147357 1632 rvkeaEEKVSRLEKQVSSMKSELETKKKELEHansgMKGKEEELKA---LEDRLELESAAKLAELKKKA 1697
Cdd:COG2433    464 -----DREISRLDREIERLERELEEERERIEE----LKRKLERLKElwkLEHSGELVPVKVVEKFTKEA 523
Mitofilin pfam09731
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...
 819-1180 5.04e-03

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.


Pssm-ID: 430783 [Multi-domain]  Cd Length: 618  Bit Score: 42.05  E-value: 5.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  819 KEKDKHLKEQQAHVENLEAdikRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQV-AE 897
Cdd:pfam09731   86 KKQVKIPRQSGVSSEVAEE---EKEATKDAAEAKAQLPKSEQEKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVkAH 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  898 VETQKKDVCTELDTHKIQVRDLLQQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEkenvilqmREGQSKEI 977
Cdd:pfam09731  163 TDSLKEASDTAEISREKATDSALQKAEALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPE--------HLDNVEEK 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  978 ETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKikqkakEMQETLKKKLLDQEAKLKKELENTVLELSQKEKQFNAKIL 1057
Cdd:pfam09731  235 VEKAQSLAKLVDQYKELVASERIVFQQELVSIFP------DIIPVLKEDNLLSNDDLNSLIAHAHREIDQLSKKLAELKK 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1058 EMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEELQEQHEIQLQEKEQEVAELKQKILRSA 1137
Cdd:pfam09731  309 REEKHIERALEKQKEELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEHLKDVLVEQ 388

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1753147357 1138 ceKEEMNRELAWLKEEGVKQNTAVRelQEQLHQQSAQTNSLSQ 1180
Cdd:pfam09731  389 --EIELQREFLQDIKEKVEEERAGR--LLKLNELLANLKGLEK 427
PRK11281 PRK11281
mechanosensitive channel MscK;
1052-1363 5.17e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.21  E-value: 5.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1052 FNAKILEMAQANSAGISDAVSRLETnqKEQIESLTEvhRRELSDVVSVWEKRLNQQAEELQeqheiQLQEKEQEVAELKQ 1131
Cdd:PRK11281    17 FLLLCLSSAFARAASNGDLPTEADV--QAQLDALNK--QKLLEAEDKLVQQDLEQTLALLD-----KIDRQKEETEQLKQ 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1132 KILRSACEKEEMNRELAWLKEEGVKQ------NTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTS 1205
Cdd:PRK11281    88 QLAQAPAKLRQAQAELEALKDDNDEEtretlsTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1206 LQERMVELEMLAEKDKLKVFELTDKLKTT-DAQFQSLQSSHERNEKSLED--------------KSLEFKKLSEELAVQL 1270
Cdd:PRK11281   168 NSQRLQQIRNLLKGGKVGGKALRPSQRVLlQAEQALLNAQNDLQRKSLEGntqlqdllqkqrdyLTARIQRLEHQLQLLQ 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1271 EIYSKKTEALLQAKTNELINI-SSNKI--NAILARIShcqNHTTKVKEALVIKTCKASELeaqLRQLTEEQNTLNSSfQQ 1347
Cdd:PRK11281   248 EAINSKRLTLSEKTVQEAQSQdEAARIqaNPLVAQEL---EINLQLSQRLLKATEKLNTL---TQQNLRVKNWLDRL-TQ 320

                          330
                   ....*....|....*.
gi 1753147357 1348 ATRQLEEkenQIKSMK 1363
Cdd:PRK11281   321 SERNIKE---QISVLK 333
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 584-1386 5.32e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.03  E-value: 5.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  584 QQESLALEELELQKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKeitiMVE 663
Cdd:pfam15921   91 QRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKED----MLE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  664 KHKTELESLQhqqdtlwteKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKtfekldvkqtelesls 743
Cdd:pfam15921  167 DSNTQIEQLR---------KMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSA---------------- 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  744 selsdILKARNKLEEELSVLK-------DQADKVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRtekelkdeinqlgl 816
Cdd:pfam15921  222 -----ISKILRELDTEISYLKgrifpveDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITG-------------- 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  817 lLKEKDKHLKEQQAHVENLEADIKrsEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVA 896
Cdd:pfam15921  283 -LTEKASSARSQANSIQSQLEIIQ--EQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELT 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  897 EVETQKKDVCTELDTHKIQVRDLLQQLENQKSEMeeklqALTQRYESQLRDTNTEQAQTKQNLIEKenvilqmREGQSKE 976
Cdd:pfam15921  360 EARTERDQFSQESGNLDDQLQKLLADLHKREKEL-----SLEKEQNKRLWDRDTGNSITIDHLRRE-------LDDRNME 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  977 IETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEMQET--LKKKLLDQEAKLKKELENTVLELSQKEKQFNA 1054
Cdd:pfam15921  428 VQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTkeMLRKVVEELTAKKMTLESSERTVSDLTASLQE 507

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1055 KILEMAQANSagisdavsrletnQKEQIESLTEVHRRELSDVVSVWEKRLNQQAEelQEQHEIQLQEKEQEVAELKQKIl 1134
Cdd:pfam15921  508 KERAIEATNA-------------EITKLRSRVDLKLQELQHLKNEGDHLRNVQTE--CEALKLQMAEKDKVIEILRQQI- 571

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1135 rsacekEEMNRELAWLKEEGVKQNTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDLNHSLRENTSLQERMVELE 1214
Cdd:pfam15921  572 ------ENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERL 645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1215 MLAEKDKLKVFELTDKLKTTDAQFQSLQSSHERNEKSLEDKSLEFKKLSEELAVQLeiysKKTEALLQAKTNELINISSN 1294
Cdd:pfam15921  646 RAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQL----KSAQSELEQTRNTLKSMEGS 721

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1295 KINAILARISHCQNHTTKVKEALVIKTcKASELEAQLRQLTEEQNTLNSSFQQATRQLEEKENQIKSMKADIEGLVMEKE 1374
Cdd:pfam15921  722 DGHAMKVAMGMQKQITAKRGQIDALQS-KIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQER 800

                          810
                   ....*....|..
gi 1753147357 1375 ALQREGGNQQQA 1386
Cdd:pfam15921  801 RLKEKVANMEVA 812
PRK12704 PRK12704
phosphodiesterase; Provisional
 1994-2125 5.38e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 5.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1994 KQKLGKEIVKLQKDLRMLRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHtQLAQKdqelemtiKE 2073
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQK--------EE 96

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1753147357 2074 TIDKaqdvEAELLESHQEETNQLYKKIAEKEDDLQRTAKRYEEILDAREEEM 2125
Cdd:PRK12704    97 NLDR----KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 327-1018 5.82e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.96  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  327 VDGASAKTLEVLQQRVKRQENLLQRCKETIQSHKE--QCALLTSEKEALQEQLDERLQELEKMKELHmAEKTKLITQLRD 404
Cdd:TIGR01612 1123 LDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDvaDKAISNDDPEEIEKKIENIVTKIDKKKNIY-DEIKKLLNEIAE 1201

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  405 AKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTAQGEELREQKEKSEKAAFE-----ELEKALSTAQK 479
Cdd:TIGR01612 1202 IEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEmgiemDIKAEMETFNI 1281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  480 AEESWRKMKAEVDEQIKAIEKTREEertSLQLELSRVKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELT--------- 550
Cdd:TIGR01612 1282 SHDDDKDHHIISKKHDENISDIREK---SLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIAniynilkln 1358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  551 ---------KKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAIlmesenklRDLQQEAETYRTR 621
Cdd:TIGR01612 1359 kikkiidevKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDI--------DECIKKIKELKNH 1430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  622 ILELESSLEKSLQESKNQSEDLAIHLEAEKNKHNKEITIMVEK-------HKTELESLQHQQDTLWTEKLQVLKQEHQTE 694
Cdd:TIGR01612 1431 ILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKkdnatndHDFNINELKEHIDKSKGCKDEADKNAKAIE 1510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  695 MEKLREKHEQEKETLLKDKESlfqaHIEEMNEKTFEKLDVKQTELESLSSELSDILKAR------NKLEEELSVLKDQAD 768
Cdd:TIGR01612 1511 KNKELFEQYKKDVTELLNKYS----ALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEkseqkiKEIKKEKFRIEDDAA 1586

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  769 KVKQELEAKLDEQKSHHQ-------------------QQVESIIKE-QEMSIQRTEKELKDEINQLGLL------LKEKD 822
Cdd:TIGR01612 1587 KNDKSNKAAIDIQLSLENfenkflkisdikkkindclKETESIEKKiSSFSIDSQDTELKENGDNLNSLqeflesLKDQK 1666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  823 KHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQstTHEQAKASEEHLAQLQQKlldleterillteqvaeVETQK 902
Cdd:TIGR01612 1667 KNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEK--IKEIAIANKEEIESIKEL-----------------IEPTI 1727

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  903 KDVCTELDTHKIQVRDLLQQLENQKSEMEE------KLQALTQRYESQLRDTNTEQAQTKQNLIEKENVILQMREGQSKE 976
Cdd:TIGR01612 1728 ENLISSFNTNDLEGIDPNEKLEEYNTEIGDiyeefiELYNIIAGCLETVSKEPITYDEIKNTRINAQNEFLKIIEIEKKS 1807

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1753147357  977 ---------------IETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKE 1018
Cdd:TIGR01612 1808 ksylddieakefdriINHFKKKLDHVNDKFTKEYSKINEGFDDISKSIENVKNSTDE 1864
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
436-869 5.95e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 5.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  436 EEIAQLRSRIKQMTAQGEELREQKEKsekaaFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSR 515
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEE-----LEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELP 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  516 VKQEAVDVMKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELEL 595
Cdd:COG4717    146 ERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  596 QKKAILMESENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSEDLAIH--------------LEAEKNKHNKEITIM 661
Cdd:COG4717    226 EEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlflvlgllallfLLLAREKASLGKEAE 305

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  662 VEKHKTELESLQHQQDTLWTEKLQVLKQEHQTEMEKLREKHEQEKETLLKDKESLFQAHIEEMNEKTFEKLDVKQTELES 741
Cdd:COG4717    306 ELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEE 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  742 LSSELSDILKARNKLEEELSVLKDQADKVKQELEAKLDEQkshhqqqvesiikeqemsiqrTEKELKDEINQLGLLLKEK 821
Cdd:COG4717    386 ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL---------------------DEEELEEELEELEEELEEL 444

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1753147357  822 DKHLKEQQAHVENLEADIKR--SEEELQQASAKLALFQSQQSTTHEQAKA 869
Cdd:COG4717    445 EEELEELREELAELEAELEQleEDGELAELLQELEELKAELRELAEEWAA 494
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 366-641 6.11e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 41.96  E-value: 6.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  366 LTSEK-EALQEQLDERLQELEKMKelhmaeKTKLITQ-LRDAKNLIEQLEQDKgmviaetkrqmhetlEMKEEEIAQLRS 443
Cdd:PTZ00108  1099 LTKEKvEKLNAELEKKEKELEKLK------NTTPKDMwLEDLDKFEEALEEQE---------------EVEEKEIAKEQR 1157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  444 riKQMTAQGEELREQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQEAVDV 523
Cdd:PTZ00108  1158 --LKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKP 1235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  524 MKKSSEQIVKLQKLHEEELASKEQELTKKFQTQERQFQEQMKIALEKSQSEYLKITQEKEQQESLALEELELQKKAILME 603
Cdd:PTZ00108  1236 KKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLE 1315

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1753147357  604 SENKLRDLQQEAETYRTRILELESSLEKSLQESKNQSE 641
Cdd:PTZ00108  1316 GSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLL 1353
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1425-1766 6.49e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.99  E-value: 6.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1425 LSKQLTDLNTQLQNSISLtekEAAISSLSKRyeEQQRELLGQVQDLSLKVE----TLSKEKVSALEQVDHLSNKFSE-WK 1499
Cdd:COG5022    782 RLRRLVDYELKWRLFIKL---QPLLSLLGSR--KEYRSYLACIIKLQKTIKrekkLRETEEVEFSLKAEVLIQKFGRsLK 856

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1500 KKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQIHSLkENLDQQNERLVCLKGEMEDKKSKLEKKECNLETEL------ 1573
Cdd:COG5022    857 AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSI-SSLKLVNLELESEIIELKKSLSSDLIENLEFKTELiarlkk 935

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1574 --------------KTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDTEQKEMLQKLQHIQELGEEKDNRvkeaeek 1639
Cdd:COG5022    936 llnnidleegpsieYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQY------- 1008

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1640 vSRLEKQVSSMkseletkkKELEHANSgmkgkeeELKALEDRLELESAAKlAELKKKAEQKIAAIKKQLLSQMEEKEQQY 1719
Cdd:COG5022   1009 -GALQESTKQL--------KELPVEVA-------ELQSASKIISSESTEL-SILKPLQKLKGLLLLENNQLQARYKALKL 1071

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1753147357 1720 KKDTeGHLGELNTKLQE----KEREIQVLEEKLQSVEGPPQSEASAVPRSA 1766
Cdd:COG5022   1072 RREN-SLLDDKQLYQLEstenLLKTINVKDLEVTNRNLVKPANVLQFIVAQ 1121
46 PHA02562
endonuclease subunit; Provisional
 675-921 6.57e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 6.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  675 QQDTLWTEKLQVLKQEHQTEMEKLRekheqeketLLKDKESLFQAHIEEMNEKTFEKLDVKQTELESLSSELSDILKARN 754
Cdd:PHA02562   167 EMDKLNKDKIRELNQQIQTLDMKID---------HIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  755 KLEEELSVLKDQADKVKQELeAKLDEQKSHHQQQVESIIKEQEM------------SIQRTEK---ELKDEINQLGLLLK 819
Cdd:PHA02562   238 ELTDELLNLVMDIEDPSAAL-NKLNTAAAKIKSKIEQFQKVIKMyekggvcptctqQISEGPDritKIKDKLKELQHSLE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  820 EkdkhLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQKLLDLETERILLTEQVAEVE 899
Cdd:PHA02562   317 K----LDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIV 392

                          250       260
                   ....*....|....*....|..
gi 1753147357  900 TQKKDVCTELDTHKIqVRDLLQ 921
Cdd:PHA02562   393 KTKSELVKEKYHRGI-VTDLLK 413
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 574-1218 6.59e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.70  E-value: 6.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  574 EYLKITQEKeQQESLALEELELQKKAILMESENKLRD-LQQEAETYrTRILELESSLEKSLQESKNQSEDLAIHLEAEKN 652
Cdd:pfam01576   12 EELQKVKER-QQKAESELKELEKKHQQLCEEKNALQEqLQAETELC-AEAEEMRARLAARKQELEEILHELESRLEEEEE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  653 KHNKeitIMVEKHKTEleslQHQQDTlwteklqvlkQEHQTEMEKLREKHEQEKETLlkdkeslfQAHIEEMNEKTFEKL 732
Cdd:pfam01576   90 RSQQ---LQNEKKKMQ----QHIQDL----------EEQLDEEEAARQKLQLEKVTT--------EAKIKKLEEDILLLE 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  733 DvkqteleslssELSDILKARNKLEEELSVLKDQAdkVKQELEAKLDEQKSHHQQQVESIIKEQEMSIQRTEKELKDEIN 812
Cdd:pfam01576  145 D-----------QNSKLSKERKLLEERISEFTSNL--AEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKR 211

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  813 QLGLLLKEKDKHLKEQQAHVENLEADIKRSEEELQQASAKLALFQSQQSTTHEQAKASEEHLAQLQQkllDLETERillt 892
Cdd:pfam01576  212 KLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQE---DLESER---- 284

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  893 EQVAEVETQKKDVCTELDTHKIQVRDLL----------QQLENQKSEMEEKLQALTQRYESQLRDTNTEQAQTKQNLIEK 962
Cdd:pfam01576  285 AARNKAEKQRRDLGEELEALKTELEDTLdttaaqqelrSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQ 364

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  963 ENVILQMREGQSKE---IETLKQKLSAKEDSFSVLHEEYEIKFKNQEKKMEKIKQKAKEmQETLKKKLLDQEAKLKKELE 1039
Cdd:pfam01576  365 LEQAKRNKANLEKAkqaLESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSE-SERQRAELAEKLSKLQSELE 443

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1040 NTVLELSQKEKQfnakilemaqanSAGISDAVSRLETNQKEQIESLTEVHRRELSdvVSVWEKRLNQQAEELQEQHEIQL 1119
Cdd:pfam01576  444 SVSSLLNEAEGK------------NIKLSKDVSSLESQLQDTQELLQEETRQKLN--LSTRLRQLEDERNSLQEQLEEEE 509

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1120 QEK---EQEVAELKQKILRSACEKEEMNRELAWLKEEGVKQNTAVRELQEQLHQQSAQTNSLSQNETKLKAQLEKLEGDL 1196
Cdd:pfam01576  510 EAKrnvERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDL 589

                          650       660
                   ....*....|....*....|...
gi 1753147357 1197 NHSLRENTSLQERMVEL-EMLAE 1218
Cdd:pfam01576  590 DHQRQLVSNLEKKQKKFdQMLAE 612
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1454-2145 7.29e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.70  E-value: 7.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1454 KRYEEQQRELLGQVQDLSLKVETLSKEKVSALEQVDHLSNKFSEwKKKAQSKFIQYHSTNKELQMQLELKTKEVSEKAEQ 1533
Cdd:pfam01576   15 QKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAE-AEEMRARLAARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1534 IHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQ--KDTE 1611
Cdd:pfam01576   94 LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNlaEEEE 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1612 QKEMLQKLQHIQE-LGEEKDNRVKEAEEKVSRLEK-------QVSSMKSELETKKKELEHANSGMKGKEEELKALEDRLE 1683
Cdd:pfam01576  174 KAKSLSKLKNKHEaMISDLEERLKKEEKGRQELEKakrklegESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1684 LESAAKLAELKK--KAEQKIAAIKKQLLS--QMEEKEQQYKKDTEGHLGELNTKLQE------------KEREIQVLEEK 1747
Cdd:pfam01576  254 EETAQKNNALKKirELEAQISELQEDLESerAARNKAEKQRRDLGEELEALKTELEDtldttaaqqelrSKREQEVTELK 333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1748 LQSVEGPPQSEASAVPRSAEHMAACAEQEEAGLQGCVQKAYEDKV-SALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGR 1826
Cdd:pfam01576  334 KALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAkQALESENAELQAELRTLQQAKQDSEHKRKKLEGQ 413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1827 YQELLIKIEHAEAKQHEDQIMINHLQKELEEKSKNysliasqhVEEEGGKNNIGAKQ--NLENVVDDVQKTLQEKELACQ 1904
Cdd:pfam01576  414 LQELQARLSESERQRAELAEKLSKLQSELESVSSL--------LNEAEGKNIKLSKDvsSLESQLQDTQELLQEETRQKL 485

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1905 ILEQKIKELDSCLVREREGHRVEMEELTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKShvvQPRLPGNMEAEHNDLE 1984
Cdd:pfam01576  486 NLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEG---KKRLQRELEALTQQLE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1985 FKlagaEQEKQKLGKEIVKLQKDLRMLRKEHQQELDIMkkeyeQEMEEKIKQ-EQEDLELKHNSTLKQLMREFHTQLAQK 2063
Cdd:pfam01576  563 EK----AAAYDKLEKTKNRLQQELDDLLVDLDHQRQLV-----SNLEKKQKKfDQMLAEEKAISARYAEERDRAEAEARE 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2064 DQELEMTIKETIDKAQDVEAELLESHQEETNQLYKKIAEKEDdlqrTAKRYEEiLDAREEEMTAKVMDLQTQLEELQNKY 2143
Cdd:pfam01576  634 KETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDD----VGKNVHE-LERSKRALEQQVEEMKTQLEELEDEL 708


                   ..
gi 1753147357 2144 QE 2145
Cdd:pfam01576  709 QA 710
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1595-1749 7.69e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 7.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1595 ESLNEALNKynqQKDTEQKEMLQKlqhIQELGEEKDNRVKEAEEKVSRLEKQVssmkseletkkKELEHANSGMKGKEEE 1674
Cdd:COG2433    376 LSIEEALEE---LIEKELPEEEPE---AEREKEHEERELTEEEEEIRRLEEQV-----------ERLEAEVEELEAELEE 438

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1753147357 1675 LKALEDRLELEsaakLAELKKKAEQKIAaikkqllsqmEEKEQQyKKDTEghLGELNTKLQEKEREIQVLEEKLQ 1749
Cdd:COG2433    439 KDERIERLERE----LSEARSEERREIR----------KDREIS-RLDRE--IERLERELEEERERIEELKRKLE 496
PRK11281 PRK11281
mechanosensitive channel MscK;
370-617 7.88e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.44  E-value: 7.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  370 KEALQEQLDErlqeLEKMKeLHMAEKTKLITQLRDAKNLIEQLEQDKgmviAETKrQMHETLEMKEEEIAQLRSRIKQMT 449
Cdd:PRK11281    38 EADVQAQLDA----LNKQK-LLEAEDKLVQQDLEQTLALLDKIDRQK----EETE-QLKQQLAQAPAKLRQAQAELEALK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  450 AQGEElrEQKEKSEKAAFEELEKALSTAQKAEESWRKMKAEVDEQIKAIEKTREEERTSLQLELSRVKQ-----EAVDVM 524
Cdd:PRK11281   108 DDNDE--ETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQirnllKGGKVG 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357  525 KK--SSEQIVKLQKlheeELASKEQELtkKFQTQERQFQEQMkIALEKSQSEYLKITQEKEQQESLALEELELQKKaiLM 602
Cdd:PRK11281   186 GKalRPSQRVLLQA----EQALLNAQN--DLQRKSLEGNTQL-QDLLQKQRDYLTARIQRLEHQLQLLQEAINSKR--LT 256

                          250
                   ....*....|....*
gi 1753147357  603 ESENKLRDLQQEAET 617
Cdd:PRK11281   257 LSEKTVQEAQSQDEA 271
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1538-1962 7.97e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 7.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1538 KENLDQQNERLVclkgEMEDKKSKLEKKECNLETEL--------KTQTAriVELQEHLTQKITEIESLNEALNkynqqkd 1609
Cdd:COG3096    298 RRQLAEEQYRLV----EMARELEELSARESDLEQDYqaasdhlnLVQTA--LRQQEKIERYQEDLEELTERLE------- 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1610 tEQKEMLqklqhiqelgEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEhansgmkgkEEELKALEDRLELESAAK 1689
Cdd:COG3096    365 -EQEEVV----------EEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD---------VQQTRAIQYQQAVQALEK 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1690 LAELKKKAEQKIAAIKkQLLSQMEEKEQQYkkdTEGHLgELNTKLQEKEREIQVLEEKLQSVEgppqSEASAVPRSAEHM 1769
Cdd:COG3096    425 ARALCGLPDLTPENAE-DYLAAFRAKEQQA---TEEVL-ELEQKLSVADAARRQFEKAYELVC----KIAGEVERSQAWQ 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1770 AAcaeqEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRleqekeemvsshsemQGRYQELLIKIEHAEAKQHEDQIMIN 1849
Cdd:COG3096    496 TA----RELLRRYRSQQALAQRLQQLRAQLAELEQRLRQ---------------QQNAERLLEEFCQRIGQQLDAAEELE 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1850 HLQKELEEKSKNYSLIASQHVEeeggkNNIGAKQNLENVVDDVQKtLQEKELACQILEQKIKELdsclvREREGhrvemE 1929
Cdd:COG3096    557 ELLAELEAQLEELEEQAAEAVE-----QRSELRQQLEQLRARIKE-LAARAPAWLAAQDALERL-----REQSG-----E 620

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1753147357 1930 ELTSKFEKLQALQQQMEGKNKPTEALEESAEEK 1962
Cdd:COG3096    621 ALADSQEVTAAMQQLLEREREATVERDELAARK 653
46 PHA02562
endonuclease subunit; Provisional
 1533-1737 8.35e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 8.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1533 QIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQ--KDT 1610
Cdd:PHA02562   189 KIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAaaKIK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1611 EQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKqvssmkseLETKKKELEHANSGMKGKEEELKALEDRLeLESAAKL 1690
Cdd:PHA02562   269 SKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITK--------IKDKLKELQHSLEKLDTAIDELEEIMDEF-NEQSKKL 339

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1753147357 1691 AELKKKAEQKIAAIK------KQLLSQMEEKEQQYKKDTEgHLGELNTKLQEK 1737
Cdd:PHA02562   340 LELKNKISTNKQSLItlvdkaKKVKAAIEELQAEFVDNAE-ELAKLQDELDKI 391
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1531-2151 8.60e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.49  E-value: 8.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1531 AEQIHSLKENLDQQNERLVCLKGEMEDKKSKLEKKECNLETELKTQTARIVELQEHLTQKITEIESLNEALNKYNQQKDT 1610
Cdd:TIGR00618  296 AAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQH 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1611 EQKEMLQKLQHIQELGEEKDNRVKEAEEKVSRLEKQVSSMKSELETKKKELEHANSGMKGKEEELKALedRLELESAAKL 1690
Cdd:TIGR00618  376 TLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELC--AAAITCTAQC 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1691 AELKKKAEQKIAAIKKQLLSQMEEKEQQYKKDTEGHLGELNTKLQEKEREIQVLEeklqsvegppqseasavpRSAEHMA 1770
Cdd:TIGR00618  454 EKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCG------------------SCIHPNP 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1771 ACAEQEEAGLQGCVQKAYEDKVSALQRSLMEKEKLLQRLEQEKEEMVSSHSEMQGRYQELLIKIEHAEAKQHEDQIMINH 1850
Cdd:TIGR00618  516 ARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVR 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1851 LQKELEEKSKNYSLIASQHVEEEGGKNNIGAKQNLENVVDDVQKTLQEKELACQILEQKIKEldsclVREREGHRVEMEE 1930
Cdd:TIGR00618  596 LQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQ-----ERVREHALSIRVL 670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 1931 LTSKFEKLQALQQQMEGKNKPTEALEESAEEKSKSHVVQPRLPGNMEAEHNDLEFKLAGAeqeKQKLGKEIVKLQKDLRM 2010
Cdd:TIGR00618  671 PKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSL---GSDLAAREDALNQSLKE 747

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753147357 2011 LRKEHQQELDIMKKEYEQEMEEKIKQEQEDLELKHNSTLKQLMREFHTQLAQKDQELEMTIKETIDKAQDVEAELLESHQ 2090
Cdd:TIGR00618  748 LMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLV 827

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1753147357 2091 EETNQLYKKIAEKEDDLQRTAKRYEEILDARE--EEMTAKVMDLQTQLEELQNKYQERLQQEE 2151
Cdd:TIGR00618  828 QEEEQFLSRLEEKSATLGEITHQLLKYEECSKqlAQLTQEQAKIIQLSDKLNGINQIKIQFDG 890
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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