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Conserved domains on  [gi|1720416765|ref|XP_030110961|]
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ELKS/Rab6-interacting/CAST family member 1 isoform X1 [Mus musculus]

Protein Classification

Cast and RBD-FIP domain-containing protein( domain architecture ID 12103785)

Cast and RBD-FIP domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
154-986 0e+00

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


:

Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 1012.82  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQ 233
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  234 DELRIQRDLNQLFQQD--SSSRTGEPCVA--ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESI 309
Cdd:pfam10174   81 DELRAQRDLNQLLQQDftTSPVDGEDKFStpELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  310 KKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDS 389
Cdd:pfam10174  161 KKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDT 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  390 KISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKeelsskdaqgeelkkraaglqseig 469
Cdd:pfam10174  241 KISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLK------------------------- 295
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  470 qvkQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 549
Cdd:pfam10174  296 ---QELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT 372
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  550 EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTI 629
Cdd:pfam10174  373 EEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERII 452
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  630 ERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEE 709
Cdd:pfam10174  453 ERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEE 532
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  710 CLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQ 789
Cdd:pfam10174  533 CSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQ 612
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  790 VKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQlqdslrkkddrieeleealresvqitaeremvlaqees 869
Cdd:pfam10174  613 MKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQ-------------------------------------- 654
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  870 artnaeKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 949
Cdd:pfam10174  655 ------LQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAAISEKDANIALL 728
                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1720416765  950 ELSSS-KKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 986
Cdd:pfam10174  729 ELSSSkKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 766
RBD-FIP super family cl09694
FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of ...
1072-1112 5.73e-07

FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of Rab11-interacting proteins (FIPs). The Rab proteins constitute the largest family of small GTPases (>60 members in mammals). Among them Rab11 is a well characterized regulator of endocytic and recycling pathways. Rab11 associates with a broad range of post-Golgi organelles, including recycling endosomes.


The actual alignment was detected with superfamily member pfam09457:

Pssm-ID: 462805 [Multi-domain]  Cd Length: 41  Bit Score: 46.95  E-value: 5.73e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1720416765 1072 TQEQLQNELEKVEGDNAELQEFANTILQQIADHCPDILEQV 1112
Cdd:pfam09457    1 SRDELQDALQKQEEENRRLEDYIDNILLRIMEHNPSILEVP 41
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
154-986 0e+00

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 1012.82  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQ 233
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  234 DELRIQRDLNQLFQQD--SSSRTGEPCVA--ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESI 309
Cdd:pfam10174   81 DELRAQRDLNQLLQQDftTSPVDGEDKFStpELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  310 KKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDS 389
Cdd:pfam10174  161 KKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDT 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  390 KISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKeelsskdaqgeelkkraaglqseig 469
Cdd:pfam10174  241 KISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLK------------------------- 295
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  470 qvkQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 549
Cdd:pfam10174  296 ---QELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT 372
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  550 EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTI 629
Cdd:pfam10174  373 EEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERII 452
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  630 ERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEE 709
Cdd:pfam10174  453 ERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEE 532
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  710 CLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQ 789
Cdd:pfam10174  533 CSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQ 612
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  790 VKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQlqdslrkkddrieeleealresvqitaeremvlaqees 869
Cdd:pfam10174  613 MKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQ-------------------------------------- 654
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  870 artnaeKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 949
Cdd:pfam10174  655 ------LQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAAISEKDANIALL 728
                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1720416765  950 ELSSS-KKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 986
Cdd:pfam10174  729 ELSSSkKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 766
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
398-972 3.77e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.01  E-value: 3.77e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  398 LRDLEEEIQMLKSNGALSSEEREEEMKQMEVyrshskfMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSR 477
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAE-------LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  478 KDTELLALQTKLETLTNQfsdskqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAG 557
Cdd:COG1196    307 LEERRRELEERLEELEEE-------LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  558 EIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRD 637
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  638 RDEREKQEEidtyKKDLKDLREKVSLLQGDLSEKEASLLDIKEhasSLASSGLKKDSRLKTLEIALEQKKEECLKMESQL 717
Cdd:COG1196    460 ALLELLAEL----LEEAALLEAALAELLEELAEAAARLLLLLE---AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  718 KKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEvdRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKV 797
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG--RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  798 ANLKHKEQVEkkkSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQ 877
Cdd:COG1196    611 ADARYYVLGD---TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  878 VEELLMAMEKVKQELESMKAklsstQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSS--SK 955
Cdd:COG1196    688 LAEEELELEEALLAEEEEER-----ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppDL 762
                          570
                   ....*....|....*..
gi 1720416765  956 KKTQEEVAALKREKDRL 972
Cdd:COG1196    763 EELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
351-983 2.64e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 97.90  E-value: 2.64e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  351 EQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEE--REEEMKQMEV 428
Cdd:PTZ00121  1113 EARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAarKAEEVRKAEE 1192
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  429 YRSHSKFMKNKVEQLKEELSSKDA--QGEELKKRAAGLQSEIGQVKQELSRKDTEllalQTKLETLTNQFSDSKQHIEVL 506
Cdd:PTZ00121  1193 LRKAEDARKAEAARKAEEERKAEEarKAEDAKKAEAVKKAEEAKKDAEEAKKAEE----ERNNEEIRKFEEARMAHFARR 1268
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  507 KESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGtqagEIHDLKDMLDVKERKVNVLQKKIEnlqEQ 586
Cdd:PTZ00121  1269 QAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK----KADEAKKKAEEAKKKADAAKKKAE---EA 1341
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  587 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDtyKKDLKDLREKVSllqg 666
Cdd:PTZ00121  1342 KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED--KKKADELKKAAA---- 1415
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  667 dlSEKEASLLDIKEHASSLASSGLKKDSRLKTLEiALEQKKEECLKMESQLKKAHEA--TLEARASPEMSDRIQQLER-- 742
Cdd:PTZ00121  1416 --AKKKADEAKKKAEEKKKADEAKKKAEEAKKAD-EAKKKAEEAKKAEEAKKKAEEAkkADEAKKKAEEAKKADEAKKka 1492
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  743 -EISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 821
Cdd:PTZ00121  1493 eEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA 1572
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  822 EDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAERemvLAQEESARTNAEKQVEEllmamEKVKQELESMKAKLSS 901
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE---AKKAEEAKIKAEELKKA-----EEEKKKVEQLKKKEAE 1644
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  902 TQQSLAE--KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQ 979
Cdd:PTZ00121  1645 EKKKAEElkKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA 1724

                   ....
gi 1720416765  980 TQNR 983
Cdd:PTZ00121  1725 EEEN 1728
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
261-978 5.08e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 5.08e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  261 ELTEENFQRL---HAEHERQAKELFLLRKTLEEMelrIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLA 337
Cdd:TIGR02168  182 ERTRENLDRLediLNELERQLKSLERQAEKAERY---KELKAELRELELALLVLRLEELREELEELQEELKEAEEELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  338 EAEMHVhhLESLLEQKEKENNMLREEMHrrfenapdsaktkALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSE 417
Cdd:TIGR02168  259 TAELQE--LEEKLEELRLEVSELEEEIE-------------ELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  418 EREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  498 DSKQHIEVLKESLT-----AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERK 572
Cdd:TIGR02168  404 RLEARLERLEDRRErlqqeIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  573 VNVLQKKIENLQEQLRDKEKQMSSLKERVK--------------------------------SLQADTTNTDTALTTLEE 620
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGVKALLKnqsglsgilgvlselisvdegyeaaieaalggRLQAVVVENLNAAKKAIA 563
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  621 ALADKE---RTIERLKEQRDR----DEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLA------- 686
Cdd:TIGR02168  564 FLKQNElgrVTFLPLDSIKGTeiqgNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElakklrp 643
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  687 --------------------------SSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEA--------RASPE 732
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitggsaktnSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELeeeleqlrKELEE 723
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  733 MSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESL---TSRQVKDQNKKVANLKHKEQVEKK 809
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEElaeAEAEIEELEAQIEQLKEELKALRE 803
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  810 KSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV---LAQEESARTNAEKQVEELLMAME 886
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLaaeIEELEELIEELESELEALLNERA 883
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  887 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAER---RKHLEEV------LEMKQEALLAAISEkDANIALLELSSSKKK 957
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELeelREKLAQLelrlegLEVRIDNLQERLSE-EYSLTLEEAEALENK 962
                          810       820
                   ....*....|....*....|.
gi 1720416765  958 TQEEVAALKREKDRLVQQLKQ 978
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKE 983
RBD-FIP pfam09457
FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of ...
1072-1112 5.73e-07

FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of Rab11-interacting proteins (FIPs). The Rab proteins constitute the largest family of small GTPases (>60 members in mammals). Among them Rab11 is a well characterized regulator of endocytic and recycling pathways. Rab11 associates with a broad range of post-Golgi organelles, including recycling endosomes.


Pssm-ID: 462805 [Multi-domain]  Cd Length: 41  Bit Score: 46.95  E-value: 5.73e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1720416765 1072 TQEQLQNELEKVEGDNAELQEFANTILQQIADHCPDILEQV 1112
Cdd:pfam09457    1 SRDELQDALQKQEEENRRLEDYIDNILLRIMEHNPSILEVP 41
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
559-981 8.87e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 43.46  E-value: 8.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  559 IHDLKDMLDVKERKVNV-LQKKIENLQ-EQLRD----KEKQMSSLKERVKS-LQADTTNTDTALTTLEEALADKERTIE- 630
Cdd:NF033838    71 LSEIQKSLDKRKHTQNVaLNKKLSDIKtEYLYElnvlKEKSEAELTSKTKKeLDAAFEQFKKDTLEPGKKVAEATKKVEe 150
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  631 ---RLKEQRDRDERekQEEIDTYKKDLKDLREkvsllqGDLSEKEASLLDIKEHASslassGLKKDSRLKTLEIALEQKK 707
Cdd:NF033838   151 aekKAKDQKEEDRR--NYPTNTYKTLELEIAE------SDVEVKKAELELVKEEAK-----EPRDEEKIKQAKAKVESKK 217
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  708 EECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDES-SKAQTEVDRLLEILKEVENEKNDKDKKIAElESLT 786
Cdd:NF033838   218 AEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPkRRAKRGVLGEPATPDKKENDAKSSDSSVGE-ETLP 296
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  787 SRQVKDQnKKVANLKHKEQVEKKKSAQMLEEARRREDSLSdssqqlqdslrkkddrIEELEEALRESVQITAEREMVLAQ 866
Cdd:NF033838   297 SPSLKPE-KKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNT----------------YKTLELEIAESDVKVKEAELELVK 359
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  867 EESARTNAEKQVeellmamEKVKQELESMKA---KLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEA------LLA 937
Cdd:NF033838   360 EEAKEPRNEEKI-------KQAKAKVESKKAeatRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPApapqpeKPA 432
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1720416765  938 AISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQ 981
Cdd:NF033838   433 PKPEKPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTE 476
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
154-986 0e+00

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 1012.82  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQ 233
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  234 DELRIQRDLNQLFQQD--SSSRTGEPCVA--ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESI 309
Cdd:pfam10174   81 DELRAQRDLNQLLQQDftTSPVDGEDKFStpELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  310 KKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDS 389
Cdd:pfam10174  161 KKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDT 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  390 KISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKeelsskdaqgeelkkraaglqseig 469
Cdd:pfam10174  241 KISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLK------------------------- 295
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  470 qvkQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 549
Cdd:pfam10174  296 ---QELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT 372
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  550 EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTI 629
Cdd:pfam10174  373 EEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERII 452
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  630 ERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEE 709
Cdd:pfam10174  453 ERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEE 532
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  710 CLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQ 789
Cdd:pfam10174  533 CSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQ 612
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  790 VKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQlqdslrkkddrieeleealresvqitaeremvlaqees 869
Cdd:pfam10174  613 MKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQ-------------------------------------- 654
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  870 artnaeKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 949
Cdd:pfam10174  655 ------LQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAAISEKDANIALL 728
                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1720416765  950 ELSSS-KKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 986
Cdd:pfam10174  729 ELSSSkKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 766
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
398-972 3.77e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.01  E-value: 3.77e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  398 LRDLEEEIQMLKSNGALSSEEREEEMKQMEVyrshskfMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSR 477
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAE-------LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  478 KDTELLALQTKLETLTNQfsdskqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAG 557
Cdd:COG1196    307 LEERRRELEERLEELEEE-------LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  558 EIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRD 637
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  638 RDEREKQEEidtyKKDLKDLREKVSLLQGDLSEKEASLLDIKEhasSLASSGLKKDSRLKTLEIALEQKKEECLKMESQL 717
Cdd:COG1196    460 ALLELLAEL----LEEAALLEAALAELLEELAEAAARLLLLLE---AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  718 KKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEvdRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKV 797
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAG--RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  798 ANLKHKEQVEkkkSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQ 877
Cdd:COG1196    611 ADARYYVLGD---TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  878 VEELLMAMEKVKQELESMKAklsstQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSS--SK 955
Cdd:COG1196    688 LAEEELELEEALLAEEEEER-----ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppDL 762
                          570
                   ....*....|....*..
gi 1720416765  956 KKTQEEVAALKREKDRL 972
Cdd:COG1196    763 EELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
439-978 1.22e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.47  E-value: 1.22e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  439 KVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAA 518
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  519 ILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLK 598
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  599 ERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDI 678
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  679 KEHASSLAsSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTE- 757
Cdd:COG1196    466 AELLEEAA-LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAl 544
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  758 --------VDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSS 829
Cdd:COG1196    545 aaalqnivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLG 624
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  830 QQL-QDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAE 908
Cdd:COG1196    625 RTLvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720416765  909 KETHLTNLRAERRKHLEEVLEMKQEALLAA----ISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 978
Cdd:COG1196    705 EERELAEAEEERLEEELEEEALEEQLEAEReellEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
351-983 2.64e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 97.90  E-value: 2.64e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  351 EQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEE--REEEMKQMEV 428
Cdd:PTZ00121  1113 EARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAarKAEEVRKAEE 1192
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  429 YRSHSKFMKNKVEQLKEELSSKDA--QGEELKKRAAGLQSEIGQVKQELSRKDTEllalQTKLETLTNQFSDSKQHIEVL 506
Cdd:PTZ00121  1193 LRKAEDARKAEAARKAEEERKAEEarKAEDAKKAEAVKKAEEAKKDAEEAKKAEE----ERNNEEIRKFEEARMAHFARR 1268
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  507 KESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGtqagEIHDLKDMLDVKERKVNVLQKKIEnlqEQ 586
Cdd:PTZ00121  1269 QAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK----KADEAKKKAEEAKKKADAAKKKAE---EA 1341
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  587 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDtyKKDLKDLREKVSllqg 666
Cdd:PTZ00121  1342 KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED--KKKADELKKAAA---- 1415
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  667 dlSEKEASLLDIKEHASSLASSGLKKDSRLKTLEiALEQKKEECLKMESQLKKAHEA--TLEARASPEMSDRIQQLER-- 742
Cdd:PTZ00121  1416 --AKKKADEAKKKAEEKKKADEAKKKAEEAKKAD-EAKKKAEEAKKAEEAKKKAEEAkkADEAKKKAEEAKKADEAKKka 1492
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  743 -EISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 821
Cdd:PTZ00121  1493 eEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA 1572
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  822 EDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAERemvLAQEESARTNAEKQVEEllmamEKVKQELESMKAKLSS 901
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE---AKKAEEAKIKAEELKKA-----EEEKKKVEQLKKKEAE 1644
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  902 TQQSLAE--KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQ 979
Cdd:PTZ00121  1645 EKKKAEElkKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA 1724

                   ....
gi 1720416765  980 TQNR 983
Cdd:PTZ00121  1725 EEEN 1728
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
261-978 5.08e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 5.08e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  261 ELTEENFQRL---HAEHERQAKELFLLRKTLEEMelrIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLA 337
Cdd:TIGR02168  182 ERTRENLDRLediLNELERQLKSLERQAEKAERY---KELKAELRELELALLVLRLEELREELEELQEELKEAEEELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  338 EAEMHVhhLESLLEQKEKENNMLREEMHrrfenapdsaktkALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSE 417
Cdd:TIGR02168  259 TAELQE--LEEKLEELRLEVSELEEEIE-------------ELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  418 EREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  498 DSKQHIEVLKESLT-----AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERK 572
Cdd:TIGR02168  404 RLEARLERLEDRRErlqqeIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERE 483
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  573 VNVLQKKIENLQEQLRDKEKQMSSLKERVK--------------------------------SLQADTTNTDTALTTLEE 620
Cdd:TIGR02168  484 LAQLQARLDSLERLQENLEGFSEGVKALLKnqsglsgilgvlselisvdegyeaaieaalggRLQAVVVENLNAAKKAIA 563
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  621 ALADKE---RTIERLKEQRDR----DEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLA------- 686
Cdd:TIGR02168  564 FLKQNElgrVTFLPLDSIKGTeiqgNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElakklrp 643
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  687 --------------------------SSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEA--------RASPE 732
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitggsaktnSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELeeeleqlrKELEE 723
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  733 MSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESL---TSRQVKDQNKKVANLKHKEQVEKK 809
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEElaeAEAEIEELEAQIEQLKEELKALRE 803
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  810 KSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV---LAQEESARTNAEKQVEELLMAME 886
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLaaeIEELEELIEELESELEALLNERA 883
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  887 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAER---RKHLEEV------LEMKQEALLAAISEkDANIALLELSSSKKK 957
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELeelREKLAQLelrlegLEVRIDNLQERLSE-EYSLTLEEAEALENK 962
                          810       820
                   ....*....|....*....|.
gi 1720416765  958 TQEEVAALKREKDRLVQQLKQ 978
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
203-979 6.79e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.28  E-value: 6.79e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  203 DEASKITIWKEQYRVVQEENQHMQMTIQALQDELR-IQRDLNQLFQQdsssrtgepcvAELTEEnFQRLHAEHERQAKEL 281
Cdd:TIGR02168  162 EEAAGISKYKERRKETERKLERTRENLDRLEDILNeLERQLKSLERQ-----------AEKAER-YKELKAELRELELAL 229
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  282 FLLRktleemelrIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTR-RLAEAEMHVHHLES-LLEQKEKENNM 359
Cdd:TIGR02168  230 LVLR---------LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlEVSELEEEIEELQKeLYALANEISRL 300
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  360 LREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEM--------------KQ 425
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEaeleelesrleeleEQ 380
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  426 MEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKD-----TELLALQTKLETLTNQFSDSK 500
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqAELEELEEELEELQEELERLE 460
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  501 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQ---AGEIHDLKDMLDVKER----KV 573
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQsglSGILGVLSELISVDEGyeaaIE 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  574 NVLQKKI-----ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQ---- 644
Cdd:TIGR02168  541 AALGGRLqavvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsy 620
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  645 --------EEIDTYKKDLKDLREKVSL--LQGDLSEKEASlldIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKME 714
Cdd:TIGR02168  621 llggvlvvDDLDNALELAKKLRPGYRIvtLDGDLVRPGGV---ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELE 697
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  715 SQLKKAHEATLEA--------RASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESL- 785
Cdd:TIGR02168  698 KALAELRKELEELeeeleqlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEl 777
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  786 --TSRQVKDQNKKVANLKHkeqvEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 863
Cdd:TIGR02168  778 aeAEAEIEELEAQIEQLKE----ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  864 LAQeesartnAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 943
Cdd:TIGR02168  854 IES-------LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1720416765  944 ANIALLE-----------LSSSKKKTQEEVAALKREKDRLVQQLKQQ 979
Cdd:TIGR02168  927 LELRLEGlevridnlqerLSEEYSLTLEEAEALENKIEDDEEEARRR 973
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
323-973 4.97e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 93.59  E-value: 4.97e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  323 AKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENN------MLREEMhRRFENAPDSAKTKALQTVIEMKDSKISSMER 396
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREkaeryqALLKEK-REYEGYELLKEKEALERQKEAIERQLASLEE 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  397 GLRDLEEEIQML-KSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSS-------KDAQGEELKKRAAGLQSEI 468
Cdd:TIGR02169  252 ELEKLTEEISELeKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASlersiaeKERELEDAEERLAKLEAEI 331
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  469 GQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDM 548
Cdd:TIGR02169  332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  549 AEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERT 628
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  629 IERLKEQRDRDEREKQEEIDTyKKDLKDLREKVSLLQGDLSEKE------------------------------------ 672
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAV-EEVLKASIQGVHGTVAQLGSVGeryataievaagnrlnnvvveddavakeaiellkrr 570
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  673 ----ASLLDI-KEHASSLASSGLKKDS------------------------------------------RLKTLEIALEQ 705
Cdd:TIGR02169  571 kagrATFLPLnKMRDERRDLSILSEDGvigfavdlvefdpkyepafkyvfgdtlvvedieaarrlmgkyRMVTLEGELFE 650
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  706 KKEECLKMESQLKKAHEATLEARAS-PEMSDRIQQLEREISRYKDESSKAQTEVDRLL-----------EILKEVENEKN 773
Cdd:TIGR02169  651 KSGAMTGGSRAPRGGILFSRSEPAElQRLRERLEGLKRELSSLQSELRRIENRLDELSqelsdasrkigEIEKEIEQLEQ 730
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  774 DKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR------EDSLSDSS-QQLQDSLRKKDDRIEEL 846
Cdd:TIGR02169  731 EEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEealndlEARLSHSRiPEIQAELSKLEEEVSRI 810
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  847 EEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEK-------ETHLTNLRAE 919
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELeaalrdlESRLGDLKKE 890
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720416765  920 RRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLV 973
Cdd:TIGR02169  891 RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
391-986 1.62e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 1.62e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  391 ISSMERGLRDLEEEIQMLKSNGALSSEEREeemKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQ 470
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRE---LELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  471 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLtakeqraAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE 550
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL-------ANLERQLEELEAQLEELESKLDELAEELAELEE 344
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  551 EKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIE 630
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  631 RLKEQRDRDEREK-QEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKE- 708
Cdd:TIGR02168  425 ELLKKLEEAELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGf 504
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  709 ----------------------ECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESS-------------- 752
Cdd:TIGR02168  505 segvkallknqsglsgilgvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELgrvtflpldsikgt 584
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  753 -------KAQTEVDRLLEILKEVENEKNDKDKKIAEL-------ESLTS--------------------------RQVKD 792
Cdd:TIGR02168  585 eiqgndrEILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvDDLDNalelakklrpgyrivtldgdlvrpggVITGG 664
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  793 QNKKVANLKHKEQvEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 872
Cdd:TIGR02168  665 SAKTNSSILERRR-EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  873 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELS 952
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823
                          650       660       670
                   ....*....|....*....|....*....|....
gi 1720416765  953 SSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 986
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESL 857
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
265-976 3.31e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.35  E-value: 3.31e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  265 ENFQRLHAEHErQAKELFLLRKTLEEMELRIETQKqtLNARDESIKKLLEMLQSKglsakaTEEDHERTRRLAEAEMHVH 344
Cdd:TIGR02169  198 QQLERLRRERE-KAERYQALLKEKREYEGYELLKE--KEALERQKEAIERQLASL------EEELEKLTEEISELEKRLE 268
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  345 HLESLLEQKEKENNMLREEMHRRFEnapdsAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMK 424
Cdd:TIGR02169  269 EIEQLLEELNKKIKDLGEEEQLRVK-----EKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELER 343
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  425 QMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Cdd:TIGR02169  344 EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA 423
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQ 584
Cdd:TIGR02169  424 DLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASE 503
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  585 EQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEAL----------------ADKERTIERLKEQRD----------- 637
Cdd:TIGR02169  504 ERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIevaagnrlnnvvveddAVAKEAIELLKRRKAgratflplnkm 583
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  638 RDEREKQEEIDT-----YKKDLKDLREKVS-----------------------------LLQGDLSEKEASLL---DIKE 680
Cdd:TIGR02169  584 RDERRDLSILSEdgvigFAVDLVEFDPKYEpafkyvfgdtlvvedieaarrlmgkyrmvTLEGELFEKSGAMTggsRAPR 663
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  681 HASSLASSGLKKDSRLKTLEIALEQKKEECL-KMESQLKKAHEATLEARASPEM----SDRIQQLEREISRYKDESSKAQ 755
Cdd:TIGR02169  664 GGILFSRSEPAELQRLRERLEGLKRELSSLQsELRRIENRLDELSQELSDASRKigeiEKEIEQLEQEEEKLKERLEELE 743
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  756 TEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR-EDSLSDSSQQLQD 834
Cdd:TIGR02169  744 EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRiEARLREIEQKLNR 823
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  835 SLRKKDDRIEELEEALRESVQITAEREMVLAQEEsartNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLT 914
Cdd:TIGR02169  824 LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE----NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899
                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720416765  915 NLR---------AERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQL 976
Cdd:TIGR02169  900 ELErkieeleaqIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
736-989 2.34e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.14  E-value: 2.34e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  736 RIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQvEKKKSAQML 815
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-DIARLEERR 311
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  816 EEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESM 895
Cdd:COG1196    312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  896 KAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQ 975
Cdd:COG1196    392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
                          250
                   ....*....|....
gi 1720416765  976 LKQQTQNRMKLMAD 989
Cdd:COG1196    472 AALLEAALAELLEE 485
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
388-898 9.30e-15

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 79.34  E-value: 9.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  388 DSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHskfmKNKVEQLKEELSSKDAQGEELKKRAAGLQSE 467
Cdd:PRK03918   192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL----KEEIEELEKELESLEGSKRKLEEKIRELEER 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  468 IGQVKQELS------RKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDalrlRLEEKETMLNKK 541
Cdd:PRK03918   268 IEELKKEIEeleekvKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK----ELEEKEERLEEL 343
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  542 TKQIQDMAEEKGtQAGEIHDLKDMLDVKERKVNVLQKKIENLQeqLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEA 621
Cdd:PRK03918   344 KKKLKELEKRLE-ELEERHELYEEAKAKKEELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKE 420
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  622 LADKERTIERLKE--------QRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKehasslasSGLKKD 693
Cdd:PRK03918   421 IKELKKAIEELKKakgkcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELE--------KVLKKE 492
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  694 SRLKTLEIALEQKKEeclkMESQLKKAHEATLEARASP--EMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENE 771
Cdd:PRK03918   493 SELIKLKELAEQLKE----LEEKLKKYNLEELEKKAEEyeKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDEL 568
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  772 KNDKDKKIAELESLTSRQVKDQNKKVANLK--HKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEA 849
Cdd:PRK03918   569 EEELAELLKELEELGFESVEELEERLKELEpfYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE 648
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720416765  850 LRESVQITAERE------------MVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAK 898
Cdd:PRK03918   649 LEELEKKYSEEEyeelreeylelsRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA 709
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
389-970 1.63e-14

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 78.14  E-value: 1.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  389 SKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEI 468
Cdd:TIGR04523   96 DKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENEL 175
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  469 GQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE---VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQI 545
Cdd:TIGR04523  176 NLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQL 255
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  546 QDMAEEKgtqageiHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKervkslqadTTNTDTALTTLEEALADK 625
Cdd:TIGR04523  256 NQLKDEQ-------NKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN---------NQKEQDWNKELKSELKNQ 319
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  626 ERTIERLKEQRDRDER---EKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIA 702
Cdd:TIGR04523  320 EKKLEEIQNQISQNNKiisQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESK 399
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  703 LEQKKEECLKMESQLKKAHEATlearaspemsdriQQLEREISRYKDESSKAQTEVDRLleilkevENEKNDKDKKIAEL 782
Cdd:TIGR04523  400 IQNQEKLNQQKDEQIKKLQQEK-------------ELLEKEIERLKETIIKNNSEIKDL-------TNQDSVKELIIKNL 459
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  783 ESLTSRQvKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREM 862
Cdd:TIGR04523  460 DNTRESL-ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKES 538
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  863 VLAQEES---------ARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQE 933
Cdd:TIGR04523  539 KISDLEDelnkddfelKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1720416765  934 ALLAAISEKDANIALLELSSSKKKTQEEVAALKREKD 970
Cdd:TIGR04523  619 LEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
452-853 1.78e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.57  E-value: 1.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  452 AQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 531
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  532 EEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDvkerkvnvlQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNT 611
Cdd:TIGR02169  754 ENVKSELKELEARIEELEEDLHKLEEALNDLEARLS---------HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRL 824
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  612 DTALTTLEEALADKERTIERLKEQRDrderEKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKehasslassglK 691
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEQIK----SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK-----------K 889
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  692 KDSRLKTLEIALEQKKEEcLKMESQLKKAHEATLEARASpEMSDRIQQLEREISRYKDESSKaqtevdrlLEILKEVENE 771
Cdd:TIGR02169  890 ERDELEAQLRELERKIEE-LEAQIEKKRKRLSELKAKLE-ALEEELSEIEDPKGEDEEIPEE--------ELSLEDVQAE 959
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  772 KNDKDKKIAELESLTSRQVKDqnkkvanlkhkeqvekkksaqmLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALR 851
Cdd:TIGR02169  960 LQRVEEEIRALEPVNMLAIQE----------------------YEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKR 1017

                   ..
gi 1720416765  852 ES 853
Cdd:TIGR02169 1018 EV 1019
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
230-848 3.94e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 3.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  230 QALQDELRiQRDLNQLFQQDsssrtgepcvaELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESI 309
Cdd:COG1196    216 RELKEELK-ELEAELLLLKL-----------RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  310 KKLLEMLQSKGLSAKATEEDHERTR-RLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFENApdsaktKALQTVIEMKD 388
Cdd:COG1196    284 EEAQAEEYELLAELARLEQDIARLEeRRRELEERLEELEEELAELEEELEELEEELEELEEEL------EEAEEELEEAE 357
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  389 SKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEI 468
Cdd:COG1196    358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  469 GQVKQELSRKDTELLALQTKLETLTNQfsdskqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQD- 547
Cdd:COG1196    438 EEEEEALEEAAEEEAELEEEEEALLEL-------LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGv 510
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  548 -MAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIE-NLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADK 625
Cdd:COG1196    511 kAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAaALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAA 590
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  626 ERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQ 705
Cdd:COG1196    591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  706 KKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESL 785
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720416765  786 TSRQVKDQNKKVANLKHKEQVEKKKSAQM----------LEEARRREDSLSDSSQQLQDSLRKKDDRIEELEE 848
Cdd:COG1196    751 EALEELPEPPDLEELERELERLEREIEALgpvnllaieeYEELEERYDFLSEQREDLEEARETLEEAIEEIDR 823
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
299-881 4.17e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 77.03  E-value: 4.17e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  299 KQTLNARDESIKKLLemlqskglsaKATEEDHERTR----RLAEAEMHVHHLESLLEQKEKENNMLREEMHRrfenapds 374
Cdd:PRK03918   171 IKEIKRRIERLEKFI----------KRTENIEELIKekekELEEVLREINEISSELPELREELEKLEKEVKE-------- 232
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  375 akTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSngalSSEEREEEMKQMEVYRSHSKFMKNKVEQ---LKEELSSKD 451
Cdd:PRK03918   233 --LEELKEEIEELEKELESLEGSKRKLEEKIRELEE----RIEELKKEIEELEEKVKELKELKEKAEEyikLSEFYEEYL 306
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  452 AQGEELKKRAAGLQSEIGQVKQELSrkdtELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEqRAAILQTEVDALRLRL 531
Cdd:PRK03918   307 DELREIEKRLSRLEEEINGIEERIK----ELEEKEERLEELKKKLKELEKRLEELEERHELYE-EAKAKKEELERLKKRL 381
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  532 EEKEtmLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQ-------------------EQLRDKEK 592
Cdd:PRK03918   382 TGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgrelteehrkELLEEYTA 459
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  593 QMSSLKERVKSLQADTTNTDTALTTLEEALADKER------TIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQG 666
Cdd:PRK03918   460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKESEliklkeLAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKG 539
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  667 DLSEKEASLLDIKEhasslassgLKKdsRLKTLEIALEQKKEECLKMESQLKKAHEATLEaraspEMSDRIQQLE----- 741
Cdd:PRK03918   540 EIKSLKKELEKLEE---------LKK--KLAELEKKLDELEEELAELLKELEELGFESVE-----ELEERLKELEpfyne 603
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  742 --------REISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSrqvKDQNKKVANLKHKEQVEKKKSAQ 813
Cdd:PRK03918   604 ylelkdaeKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS---EEEYEELREEYLELSRELAGLRA 680
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720416765  814 MLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 881
Cdd:PRK03918   681 ELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEI 748
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
434-931 4.42e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 77.03  E-value: 4.42e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  434 KFMKNKVEQLKEELSSKdaqgEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQH---IEVLKESL 510
Cdd:PRK03918   172 KEIKRRIERLEKFIKRT----ENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeeIEELEKEL 247
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  511 TAKEQRAAILQTEVDALRLRLEEKETMLN------KKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQ 584
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEeleekvKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIE 327
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  585 EQLRD---KEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKER-----------TIERLKEQRDRDEREKQEeidtY 650
Cdd:PRK03918   328 ERIKEleeKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEElerlkkrltglTPEKLEKELEELEKAKEE----I 403
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  651 KKDLKDLREKVSLLQGDLSEKEASLLDIK---------------EHASSLASSGLKKDSRLKTLEIALEQKKEECLKMES 715
Cdd:PRK03918   404 EEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELR 483
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  716 QLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTE------------------VDRLLEILKEVENEKNDKDK 777
Cdd:PRK03918   484 ELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEeyeklkekliklkgeiksLKKELEKLEELKKKLAELEK 563
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  778 KIAELEsltsRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQIT 857
Cdd:PRK03918   564 KLDELE----EELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETE 639
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720416765  858 AEREMVLAQ-EESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMK 931
Cdd:PRK03918   640 KRLEELRKElEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
382-899 9.51e-14

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 75.83  E-value: 9.51e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  382 TVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRA 461
Cdd:TIGR04523  204 SNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKI 283
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  462 AGLQSEIGQVKQELS------------RKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRL 529
Cdd:TIGR04523  284 KELEKQLNQLKSEISdlnnqkeqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQR 363
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  530 RLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTT 609
Cdd:TIGR04523  364 ELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIK 443
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  610 NTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEK---EASLLDIKEHASSLA 686
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKkelEEKVKDLTKKISSLK 523
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  687 SSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAheatlearaspEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILK 766
Cdd:TIGR04523  524 EKIEKLESEKKEKESKISDLEDELNKDDFELKKE-----------NLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELID 592
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  767 EVENEKNDKDKKIAELESLTS------RQVKDQNKKVANLKHKEQVEKKKSAQMLE----EARRREDSLSDSSQQLQDSL 836
Cdd:TIGR04523  593 QKEKEKKDLIKEIEEKEKKISslekelEKAKKENEKLSSIIKNIKSKKNKLKQEVKqikeTIKEIRNKWPEIIKKIKESK 672
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720416765  837 RKKDDRIEELEEALRESVQITAER--EMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKL 899
Cdd:TIGR04523  673 TKIDDIIELMKDWLKELSLHYKKYitRMIRIKDLPKLEEKYKEIEKELKKLDEFSKELENIIKNF 737
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
465-846 1.76e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 1.76e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  465 QSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQ 544
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  545 IQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAD 624
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAA 835
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  625 KERTIERLKEQrdrderekqeeidtykkdLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALE 704
Cdd:TIGR02168  836 TERRLEDLEEQ------------------IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  705 QKKEECLKMESQLKKAHEATLEARAS-PEMSDRIQQLEREISRYKDE-SSKAQTEvdrlleiLKEVENEKNDKDKKIAEL 782
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKlAQLELRLEGLEVRIDNLQERlSEEYSLT-------LEEAEALENKIEDDEEEA 970
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720416765  783 EsltsRQVKDQNKKVA-----NLKHKEQVEKKKsaQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEEL 846
Cdd:TIGR02168  971 R----RRLKRLENKIKelgpvNLAAIEEYEELK--ERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
263-847 1.78e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 1.78e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  263 TEENFQRLH---AEHERQAKELFLLRKTLEE-MELRIE---TQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRR 335
Cdd:COG1196    184 TEENLERLEdilGELERQLEPLERQAEKAERyRELKEElkeLEAELLLLKLRELEAELEELEAELEELEAELEELEAELA 263
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  336 LAEAEmhVHHLESLLEQKEKENNMLREEMHRRfenapdSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALS 415
Cdd:COG1196    264 ELEAE--LEELRLELEELELELEEAQAEEYEL------LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  416 SEEREEEMKQMEVYrshskfmKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQ 495
Cdd:COG1196    336 EEELEELEEELEEA-------EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  496 FSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNV 575
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  576 LQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTD---TALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKK 652
Cdd:COG1196    489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA 568
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  653 DLKDLREKVSLLQ---GDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARA 729
Cdd:COG1196    569 AKAGRATFLPLDKiraRAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  730 SPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKK 809
Cdd:COG1196    649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1720416765  810 KSAQMLEEARRRE--------------DSLSDSSQQLQDSLRKKDDRIEELE 847
Cdd:COG1196    729 QLEAEREELLEELleeeelleeealeeLPEPPDLEELERELERLEREIEALG 780
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
439-758 2.75e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.72  E-value: 2.75e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  439 KVEQLKEELsskdaqgEELKKRAAGLQSEIGQVKQELSRKDTE------LLALQTKLE-----TLTNQFSDSKQHIEVLK 507
Cdd:TIGR02169  171 KKEKALEEL-------EEVEENIERLDLIIDEKRQQLERLRRErekaerYQALLKEKReyegyELLKEKEALERQKEAIE 243
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  508 ESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQ--------AGEIHDLKDMLDVKERKVNVLQKK 579
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvkekigelEAEIASLERSIAEKERELEDAEER 323
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  580 IENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERL--KEQRDRDE-REKQEEIDTYKKDLKD 656
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkEFAETRDElKDYREKLEKLKREINE 403
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  657 LREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARAS-PEMSD 735
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEyDRVEK 483
                          330       340
                   ....*....|....*....|...
gi 1720416765  736 RIQQLEREISRYKDESSKAQTEV 758
Cdd:TIGR02169  484 ELSKLQRELAEAEAQARASEERV 506
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
398-774 5.91e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 5.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  398 LRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSR 477
Cdd:TIGR02169  676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN 755
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  478 KDTELLALQTKLETLTNQFSDSKQHIEVLKESLT-----AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEK 552
Cdd:TIGR02169  756 VKSELKELEARIEELEEDLHKLEEALNDLEARLShsripEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI 835
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  553 GTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQadttntdtalttleealADKERTIERL 632
Cdd:TIGR02169  836 QELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK-----------------KERDELEAQL 898
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  633 KEQRDRdEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASsglkkdsrlktleiaLEQKKEECLK 712
Cdd:TIGR02169  899 RELERK-IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS---------------LEDVQAELQR 962
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720416765  713 MESQLKKAHEATLEAraspemsdrIQQLEREISRYKDESSKAQT---EVDRLLEILKEVENEKND 774
Cdd:TIGR02169  963 VEEEIRALEPVNMLA---------IQEYEEVLKRLDELKEKRAKleeERKAILERIEEYEKKKRE 1018
PTZ00121 PTZ00121
MAEBL; Provisional
272-1024 1.23e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.87  E-value: 1.23e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  272 AEHERQAKELFLLRKTleEMELRIETQKQTLNARD-ESIKKLLEMLQSKGLSaKATEEDHERTRRLAEAEMHVHHLESLL 350
Cdd:PTZ00121  1145 ARKAEDAKRVEIARKA--EDARKAEEARKAEDAKKaEAARKAEEVRKAEELR-KAEDARKAEAARKAEEERKAEEARKAE 1221
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  351 EQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEiQMLKSNGALSSEE--REEEMKQMEV 428
Cdd:PTZ00121  1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-EARKADELKKAEEkkKADEAKKAEE 1300
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  429 YRSHSKFMKN-----KVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHI 503
Cdd:PTZ00121  1301 KKKADEAKKKaeeakKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKA 1380
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  504 EVLKESltAKEQRAAilqtevDALRLRLEEKETMLN--KKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKvnvlqKKIE 581
Cdd:PTZ00121  1381 DAAKKK--AEEKKKA------DEAKKKAEEDKKKADelKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEA-----KKAD 1447
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  582 NLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKV 661
Cdd:PTZ00121  1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA 1527
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  662 SLLQGDLSEKEASLLDIKEHASSL-ASSGLKKDSRLKTLEIA--LEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQ 738
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELkKAEELKKAEEKKKAEEAkkAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  739 QLER----EISRYKDESSKAQTEVDRLLEILKEVENE---KNDKDKKIAELESLTSRQVK---DQNKKVANLKHKEQVEK 808
Cdd:PTZ00121  1608 KAEEakkaEEAKIKAEELKKAEEEKKKVEQLKKKEAEekkKAEELKKAEEENKIKAAEEAkkaEEDKKKAEEAKKAEEDE 1687
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  809 KKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV 888
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  889 KQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEAllaaisekdANIALLELSSSKKKTQEEVAALKRE 968
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEG---------GKEGNLVINDSKEMEDSAIKEVADS 1838
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720416765  969 KDRLVQQLKQQTQNRMKLMADNYEDDHFRSSRSNQTNHKpspDQIIQPLLELDQNR 1024
Cdd:PTZ00121  1839 KNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLK---EDDEEEIEEADEIE 1891
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
154-978 2.72e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 2.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALrkdEASKITIWKEQYRVvQEENQHMQMTIQALQ 233
Cdd:TIGR02169  189 LDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEAL---ERQKEAIERQLASL-EEELEKLTEEISELE 264
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  234 DEL-RIQRDLNQLFQQdsssrtgepcVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKL 312
Cdd:TIGR02169  265 KRLeEIEQLLEELNKK----------IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  313 LEmlQSKGLSAKATEEDHER---TRRLAEAEMHVHHLESLLEQKEKENNMLREEmhrrfenapdsakTKALQTVIEMKDS 389
Cdd:TIGR02169  335 LA--EIEELEREIEEERKRRdklTEEYAELKEELEDLRAELEEVDKEFAETRDE-------------LKDYREKLEKLKR 399
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  390 KISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIG 469
Cdd:TIGR02169  400 EINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYD 479
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTA-----------KEQRAAILQ-------------TEVD 525
Cdd:TIGR02169  480 RVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlgsvGERYATAIEvaagnrlnnvvveDDAV 559
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  526 ALRLRLEEKETMLNKKT----KQIQDMAEEKG--TQAGEIHDLKDMLDVKERKVNVL---------------------QK 578
Cdd:TIGR02169  560 AKEAIELLKRRKAGRATflplNKMRDERRDLSilSEDGVIGFAVDLVEFDPKYEPAFkyvfgdtlvvedieaarrlmgKY 639
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  579 KIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDER---EKQEEIDTYKKDLK 655
Cdd:TIGR02169  640 RMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENrldELSQELSDASRKIG 719
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  656 DLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLkkaheATLEARASPEmsd 735
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL-----NDLEARLSHS--- 791
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  736 RIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELEsltsRQVKDQNKKVANLKHKEQVEKKKSAQML 815
Cdd:TIGR02169  792 RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQ----EQRIDLKEQIKSIEKEIENLNGKKEELE 867
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  816 EEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMvlaqeesartnAEKQVEELLMAMEKVKQELESM 895
Cdd:TIGR02169  868 EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEK-----------KRKRLSELKAKLEALEEELSEI 936
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  896 KAKLSSTQQSLAEkETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQ 975
Cdd:TIGR02169  937 EDPKGEDEEIPEE-ELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015

                   ...
gi 1720416765  976 LKQ 978
Cdd:TIGR02169 1016 KRE 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
690-979 3.09e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 3.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  690 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASpemSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVE 769
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEEL---EAELAELEAELEELRLELEELELELEEAQAEEYELL 294
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  770 NEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQmLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEA 849
Cdd:COG1196    295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE-LEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  850 LRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLE 929
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720416765  930 MKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQ 979
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
398-929 3.18e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.84  E-value: 3.18e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  398 LRDLEEEIQMLKSNG------ALSSEERE--EEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIG 469
Cdd:PRK02224   189 LDQLKAQIEEKEEKDlherlnGLESELAEldEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIA 268
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 549
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  550 EEkgtqageIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAD----TTNTDTALTTLEEALADK 625
Cdd:PRK02224   349 ED-------ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdaPVDLGNAEDFLEELREER 421
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  626 ERTIERLKEQR-----DRDEREKQEEI------DTYKKDLKD--LREKVSLLQGDLSEKEASLLDIKEHASSLassglkk 692
Cdd:PRK02224   422 DELREREAELEatlrtARERVEEAEALleagkcPECGQPVEGspHVETIEEDRERVEELEAELEDLEEEVEEV------- 494
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  693 DSRLKTLEIALE-----QKKEECLKMESQLKKAHEATLEAR--ASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEIL 765
Cdd:PRK02224   495 EERLERAEDLVEaedriERLEERREDLEELIAERRETIEEKreRAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEV 574
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  766 KEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKksAQMLEEARRREDSLSDSSQQLQDSLrkKDDRIEE 845
Cdd:PRK02224   575 AELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREAL--AELNDERRERLAEKRERKRELEAEF--DEARIEE 650
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  846 LEEALRESVQITAEREMVLAQEESARTNAEKQ---VEELLMAMEKVKQELESMKAK---LSSTQQSLAEKETHLTNLRAE 919
Cdd:PRK02224   651 AREDKERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELEELRERREALENRveaLEALYDEAEELESMYGDLRAE 730
                          570
                   ....*....|
gi 1720416765  920 RRKHLEEVLE 929
Cdd:PRK02224   731 LRQRNVETLE 740
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
465-972 8.33e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 69.68  E-value: 8.33e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  465 QSEIGQVKQELSRK-DTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Cdd:PRK02224   186 RGSLDQLKAQIEEKeEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRE 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  544 QIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKK-------IENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Cdd:PRK02224   266 TIAETEREREELAEEVRDLRERLEELEEERDDLLAEaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  617 TLEEALADKERTIERLKEQRDRDEREKQ---EEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKD 693
Cdd:PRK02224   346 SLREDADDLEERAEELREEAAELESELEearEAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELR 425
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  694 SRLKTLEIALEQkkeeclkMESQLKKAhEATLEARASPEMSDRIqqlerEISRYKDESSKAQTEVDRLLEILKEVENEKN 773
Cdd:PRK02224   426 EREAELEATLRT-------ARERVEEA-EALLEAGKCPECGQPV-----EGSPHVETIEEDRERVEELEAELEDLEEEVE 492
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  774 DKDKKIAELESL--TSRQVKDQNKKVANLkhKEQVEKKKSAqmLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALR 851
Cdd:PRK02224   493 EVEERLERAEDLveAEDRIERLEERREDL--EELIAERRET--IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAE 568
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  852 ESVQITAEREMVLAQEESARTNAEKqVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRaERRKHLEEvlEMK 931
Cdd:PRK02224   569 EAREEVAELNSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKR-ERKRELEA--EFD 644
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1720416765  932 QEALLAAISEKD------ANIA--LLELSSSKKKTQEEVAALKREKDRL 972
Cdd:PRK02224   645 EARIEEAREDKEraeeylEQVEekLDELREERDDLQAEIGAVENELEEL 693
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
259-942 3.13e-11

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 68.07  E-value: 3.13e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  259 VAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAE 338
Cdd:TIGR00618  181 LALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQ 260
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  339 AEMHVHHLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEE 418
Cdd:TIGR00618  261 LLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSI 340
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  419 REEEMKQMEVYRSHSKF-MKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
Cdd:TIGR00618  341 EEQRRLLQTLHSQEIHIrDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFR 420
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  498 DSKQHIEVLKESLTAKEQRAAILQtevdalrLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQ 577
Cdd:TIGR00618  421 DLQGQLAHAKKQQELQQRYAELCA-------AAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVL 493
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  578 KKIENLQEQLRDKEKQMSSLKERVKSL------QADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDT-- 649
Cdd:TIGR00618  494 ARLLELQEEPCPLCGSCIHPNPARQDIdnpgplTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSfs 573
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  650 --------YKKDLKDLREKVSLLQgDLSEKEASLLDIKEHASSLASsgLKKDSRLKTLEIAL-EQKKEECLKMESQLKKA 720
Cdd:TIGR00618  574 iltqcdnrSKEDIPNLQNITVRLQ-DLTEKLSEAEDMLACEQHALL--RKLQPEQDLQDVRLhLQQCSQELALKLTALHA 650
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  721 HEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANL 800
Cdd:TIGR00618  651 LQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSL 730
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  801 KHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDS-------LRKKDDRIEELEEALRESVQITAEREMVLAQ-EESART 872
Cdd:TIGR00618  731 GSDLAAREDALNQSLKELMHQARTVLKARTEAHFNnneevtaALQTGAELSHLAAEIQFFNRLREEDTHLLKTlEAEIGQ 810
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  873 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLrAERRKHLEEVleMKQEALLAAISEK 942
Cdd:TIGR00618  811 EIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKY-EECSKQLAQL--TQEQAKIIQLSDK 877
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
455-673 3.71e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 66.33  E-value: 3.71e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  455 EELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK 534
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  535 ETMLNKKTKQIQDMAEEKGTQ----AGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 610
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720416765  611 TDTALTTLEEALADKERTIERLKeqrdRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEA 673
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLE----KELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
277-657 1.16e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 1.16e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  277 QAKELFLLRKTLEEMELRIETQKQTLNArdesikkllemlqskglsakateedhertrrlaeaemhvhhLESLLEQKEKE 356
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAE-----------------------------------------LRKELEELEEE 713
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  357 nnmlreemhrrfenapdsakTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRShskfm 436
Cdd:TIGR02168  714 --------------------LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE----- 768
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  437 knKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQR 516
Cdd:TIGR02168  769 --RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  517 AAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSS 596
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720416765  597 LKERVKSLQADTTNTDTALTTLEEALADkerTIERLKEQRDRDEREKQEEIDTYKKDLKDL 657
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQERLSEEYSLTLE---EAEALENKIEDDEEEARRRLKRLENKIKEL 984
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
488-1032 1.67e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.45  E-value: 1.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  488 KLETLTNQFSDSKQHIE-VLKESLTAKEQ-RAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 565
Cdd:PRK02224   163 KLEEYRERASDARLGVErVLSDQRGSLDQlKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV 242
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  566 LDVKERK---VNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALttlEEALADKERT---IERLKEQRDRD 639
Cdd:PRK02224   243 LEEHEERreeLETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER---DDLLAEAGLDdadAEAVEARREEL 319
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  640 EREKQEeidtykkdlkdlrekvslLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLeialeqkKEECLKMESQLKK 719
Cdd:PRK02224   320 EDRDEE------------------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEEL-------REEAAELESELEE 374
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  720 AHEATLEARaspemsDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELEsltsrqvkdqnkkvAN 799
Cdd:PRK02224   375 AREAVEDRR------EEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELE--------------AT 434
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  800 LKHKEQVeKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARtNAEKQVE 879
Cdd:PRK02224   435 LRTARER-VEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLV-EAEDRIE 512
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  880 ELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK-- 957
Cdd:PRK02224   513 RLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESle 592
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  958 ----TQEEVAALKREKDRLVQQLKQQ----TQNRMKL---------MADNYEDDHFRSSRSNQTNHKPSPDQIIQPLLEL 1020
Cdd:PRK02224   593 rirtLLAAIADAEDEIERLREKREALaelnDERRERLaekrerkreLEAEFDEARIEEAREDKERAEEYLEQVEEKLDEL 672
                          570
                   ....*....|..
gi 1720416765 1021 DQNRSKLKLYIG 1032
Cdd:PRK02224   673 REERDDLQAEIG 684
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
250-788 2.06e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 2.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  250 SSSRTGEPCVAELTEENFQRLHAE-HERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlqskglSAKATEE 328
Cdd:PRK02224   172 SDARLGVERVLSDQRGSLDQLKAQiEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRD-------EADEVLE 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  329 DHERTR-RLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFEnapdsaktkALQTVIEMKDSKISsmERGLRDLEEEIQM 407
Cdd:PRK02224   245 EHEERReELETLEAEIEDLRETIAETEREREELAEEVRDLRE---------RLEELEEERDDLLA--EAGLDDADAEAVE 313
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  408 LKSNgALSSEEREEEMKQMEVYRSHSKFmKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQT 487
Cdd:PRK02224   314 ARRE-ELEDRDEELRDRLEECRVAAQAH-NEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEE 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  488 KLETLTNQFSDS-------KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK----------KTKQIQDMAE 550
Cdd:PRK02224   392 EIEELRERFGDApvdlgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIE 471
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  551 EKgtqAGEIHDLKDMLDVKERKVNVLQKKIENLqEQLRDKEKQMSSLKERVKSLQadttntdTALTTLEEALADKERTIE 630
Cdd:PRK02224   472 ED---RERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLE-------ELIAERRETIEEKRERAE 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  631 RLKEQRDRDE---REKQEEIDTYKKDLKDLREKVSLLQGDLSEKEA---SLLDIKEHASSLASSGLKKDSRLKTLEIALE 704
Cdd:PRK02224   541 ELRERAAELEaeaEEKREAAAEAEEEAEEAREEVAELNSKLAELKErieSLERIRTLLAAIADAEDEIERLREKREALAE 620
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  705 QKKE--ECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEkndkdkkIAEL 782
Cdd:PRK02224   621 LNDErrERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENE-------LEEL 693

                   ....*.
gi 1720416765  783 ESLTSR 788
Cdd:PRK02224   694 EELRER 699
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
150-801 2.67e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 2.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  150 TIMDLQTQLKEVLRENDLLrKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTI 229
Cdd:pfam15921  111 SVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEI 189
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  230 QALQDELRiQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLE--------EMELRIETQK-- 299
Cdd:pfam15921  190 RSILVDFE-EASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEalksesqnKIELLLQQHQdr 268
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  300 --QTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAE--MHVHHLESLLEQKEKENNMLREEmHRRFENAPDSA 375
Cdd:pfam15921  269 ieQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQnsMYMRQLSDLESTVSQLRSELREA-KRMYEDKIEEL 347
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  376 KTKALQTVIEMKDSKIS----SMERGlrDLEEEIQMLKSNgaLSSEEREEEMKQMEVYRSHSKFMKNK--VEQLKEELSS 449
Cdd:pfam15921  348 EKQLVLANSELTEARTErdqfSQESG--NLDDQLQKLLAD--LHKREKELSLEKEQNKRLWDRDTGNSitIDHLRRELDD 423
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  450 KDAQGEELKKRAAGLQSEI-GQVKQELSRKDTELLALQtKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALR 528
Cdd:pfam15921  424 RNMEVQRLEALLKAMKSECqGQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT 502
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  529 LRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKD-----------------MLDVKERKVNVLQKKIEN--------- 582
Cdd:pfam15921  503 ASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNegdhlrnvqtecealklQMAEKDKVIEILRQQIENmtqlvgqhg 582
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  583 ------------LQEQLRDKEKQMSSLK-------ERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDrderEK 643
Cdd:pfam15921  583 rtagamqvekaqLEKEINDRRLELQEFKilkdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERD----QL 658
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  644 QEEIDTYKKDLKDLREKVSLLQGDLSEK----EASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLkK 719
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRNFRNKseemETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQI-T 737
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  720 AHEATLEAraspeMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNdkdKKIAELESLTSrQVKDQNKKVAN 799
Cdd:pfam15921  738 AKRGQIDA-----LQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKN---KMAGELEVLRS-QERRLKEKVAN 808

                   ..
gi 1720416765  800 LK 801
Cdd:pfam15921  809 ME 810
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
388-976 3.28e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 3.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  388 DSKIssmERGLRDLEEEIQMLKSNGALSSEER------EEEMKQMEVYRS-HSKFMKNKVEQLKEELSSKDAQGEELKKR 460
Cdd:TIGR02169  169 DRKK---EKALEELEEVEENIERLDLIIDEKRqqlerlRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQ 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  461 AAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDskqhievlkesLTAKEQRAaiLQTEVDALRLRLEEKETMLNK 540
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKD-----------LGEEEQLR--VKEKIGELEAEIASLERSIAE 312
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  541 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE 620
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  621 ALADKERTIERLKEQRDRDEREKQ---EEIDTYKKDLKDLREKVSLLQGD-------LSEKEASLLDIKEHASSLASSGL 690
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQrlsEELADLNAAIAGIEAKINELEEEkedkaleIKKQEWKLEQLAADLSKYEQELY 472
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  691 KKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEM-SDRIQ---QLEREISRYKDESSKAqTEV---DRLLE 763
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVlKASIQgvhGTVAQLGSVGERYATA-IEVaagNRLNN 551
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  764 ILKEVENEKND-----KDKKIAELESLTSRQVKDQNKKVANLKHKEQV----------EKKKSA-----------QMLEE 817
Cdd:TIGR02169  552 VVVEDDAVAKEaiellKRRKAGRATFLPLNKMRDERRDLSILSEDGVIgfavdlvefdPKYEPAfkyvfgdtlvvEDIEA 631
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  818 ARR--------------------------REDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESAR 871
Cdd:TIGR02169  632 ARRlmgkyrmvtlegelfeksgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL 711
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  872 TNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAErRKHLEEVLEMKQEAlLAAISEKDANIALLEL 951
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE-LKELEARIEELEED-LHKLEEALNDLEARLS 789
                          650       660
                   ....*....|....*....|....*
gi 1720416765  952 SSSKKKTQEEVAALKREKDRLVQQL 976
Cdd:TIGR02169  790 HSRIPEIQAELSKLEEEVSRIEARL 814
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
268-978 4.18e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.37  E-value: 4.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  268 QRLHAEHERQAKELFLLRKT-------LEEMELRIETQKQTLNARDESIKKLLEMLQS---KGLSAKATEEDH------- 330
Cdd:pfam15921   92 RRLNESNELHEKQKFYLRQSvidlqtkLQEMQMERDAMADIRRRESQSQEDLRNQLQNtvhELEAAKCLKEDMledsntq 171
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  331 -ERTRRLAEA-EMHVHHLESLLEQKEKENNMLREEmHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQML 408
Cdd:pfam15921  172 iEQLRKMMLShEGVLQEIRSILVDFEEASGKKIYE-HDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEAL 250
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  409 KSngalsseerEEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTK 488
Cdd:pfam15921  251 KS---------ESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSD 321
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  489 LETLTNQFSDSkqhievLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV 568
Cdd:pfam15921  322 LESTVSQLRSE------LREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSL 395
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  569 KERKVNVLQKK-------IENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTleeALADKERTIERLKEQRDRDER 641
Cdd:pfam15921  396 EKEQNKRLWDRdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMA---AIQGKNESLEKVSSLTAQLES 472
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  642 EKQ------EEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASS---GLKKDSRLKTLEIALEQKKEECLK 712
Cdd:pfam15921  473 TKEmlrkvvEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdlKLQELQHLKNEGDHLRNVQTECEA 552
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  713 MESQLKKAHEATLEARASPE-MSDRIQQLEREISRYKDESSKAQTEV-DRLLEiLKEVENEKNDKDKKIAELESLTS--- 787
Cdd:pfam15921  553 LKLQMAEKDKVIEILRQQIEnMTQLVGQHGRTAGAMQVEKAQLEKEInDRRLE-LQEFKILKDKKDAKIRELEARVSdle 631
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  788 -RQVKDQNKKVANLKHKEQVEKKKSaQMLEE---ARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQiTAEREmv 863
Cdd:pfam15921  632 lEKVKLVNAGSERLRAVKDIKQERD-QLLNEvktSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLK-SAQSE-- 707
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  864 LAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 943
Cdd:pfam15921  708 LEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNK 787
                          730       740       750
                   ....*....|....*....|....*....|....*
gi 1720416765  944 ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 978
Cdd:pfam15921  788 MAGELEVLRSQERRLKEKVANMEVALDKASLQFAE 822
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
487-985 6.09e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 63.70  E-value: 6.09e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  487 TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE-EKGTQAGEIHDLKDM 565
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNgELSAADAAVAKDRSE 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  566 LDV-KERKVNVLQKKIENL---QEQLRDKEKQMSSLKERVKSLQA-----DTTNTDTALTTLEEALADKERTIERLKEQR 636
Cdd:pfam12128  324 LEAlEDQHGAFLDADIETAaadQEQLPSWQSELENLEERLKALTGkhqdvTAKYNRRRSKIKEQNNRDIAGIKDKLAKIR 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  637 DRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEaslldiKEHASSLASSGLKKDSRLKTLEIAL--EQKKEECLKME 714
Cdd:pfam12128  404 EARDRQLAVAEDDLQALESELREQLEAGKLEFNEEE------YRLKSRLGELKLRLNQATATPELLLqlENFDERIERAR 477
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  715 SQLKKAHEATLEAR--------ASPEMSDRIQQLEREISRYKDESSKAQTEVD----RLLEILKEVENEKNDKDKKIAEL 782
Cdd:pfam12128  478 EEQEAANAEVERLQselrqarkRRDQASEALRQASRRLEERQSALDELELQLFpqagTLLHFLRKEAPDWEQSIGKVISP 557
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  783 E---------SLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDslsdssqQLQDSLRKKDDRIEELEEALres 853
Cdd:pfam12128  558 EllhrtdldpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLD-------KAEEALQSAREKQAAAEEQL--- 627
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  854 VQITAEREMVLAQEESART---NAEKQVEELLMAME----KVKQELESMKAKLSSTQQSLAEKETHLTN----LRAERRK 922
Cdd:pfam12128  628 VQANGELEKASREETFARTalkNARLDLRRLFDEKQsekdKKNKALAERKDSANERLNSLEAQLKQLDKkhqaWLEEQKE 707
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720416765  923 HLEEVLEMKQEALLAAISEKDANIALLElssskkktqEEVAALKREKDRLVQQLKQQTQNRMK 985
Cdd:pfam12128  708 QKREARTEKQAYWQVVEGALDAQLALLK---------AAIAARRSGAKAELKALETWYKRDLA 761
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
265-988 1.29e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.68  E-value: 1.29e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  265 ENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKllEMLQSKGLSAKATEEDHERTRRLAEAEMHVH 344
Cdd:pfam02463  234 LNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE--KKLQEEELKLLAKEEEELKSELLKLERRKVD 311
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  345 HLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMK 424
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  425 QMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Cdd:pfam02463  392 LKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ-----------DMAEEKGTQAGEIHDLKDMLDVKERKV 573
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLalikdgvggriISAHGRLGDLGVAVENYKVAISTAVIV 551
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  574 NVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE--ALADKERTIERLKEQRDRDEREKQEEIDTYK 651
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidPILNLAQLDKATLEADEDDKRAKVVEGILKD 631
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  652 KDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASP 731
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  732 EMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVE-------NEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKE 804
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEeeeeksrLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEE 791
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  805 QVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLma 884
Cdd:pfam02463  792 KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL-- 869
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  885 MEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAA 964
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949
                          730       740
                   ....*....|....*....|....
gi 1720416765  965 LKREKDRLVQQLKQQTQNRMKLMA 988
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELG 973
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
193-746 2.09e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 2.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  193 ELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELR-IQRDLNQLFQQDSSSRTGepcvAELTEENFQRLH 271
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYeLLAELARLEQDIARLEER----RRELEERLEELE 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  272 AEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEED-HERTRRLAEAEMHVHHLESLL 350
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEElEELAEELLEALRAAAELAAQL 402
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  351 EQKEK--ENNMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEmkqmev 428
Cdd:COG1196    403 EELEEaeEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE------ 476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  429 yrshskfmkNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLAlqtklETLTNQFSDSKQHIEVLKE 508
Cdd:COG1196    477 ---------AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA-----GAVAVLIGVEAAYEAALEA 542
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  509 SLTAKEQRaAILQTEVDALRLRLEEKETMLNKKT-----KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENL 583
Cdd:COG1196    543 ALAAALQN-IVVEDDEVAAAAIEYLKAAKAGRATflpldKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  584 QEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKvsl 663
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA--- 698
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  664 lQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARAspEMSDRIQQLERE 743
Cdd:COG1196    699 -LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE--ELERELERLERE 775

                   ...
gi 1720416765  744 ISR 746
Cdd:COG1196    776 IEA 778
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
350-989 3.23e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 61.29  E-value: 3.23e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  350 LEQKEKENNMLREEMH--RRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNgALSSEEREEEMKQME 427
Cdd:pfam15921  115 LQTKLQEMQMERDAMAdiRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKM-MLSHEGVLQEIRSIL 193
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  428 VYRSHSKfMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLAL----QTKLETLTNQFSDS-KQH 502
Cdd:pfam15921  194 VDFEEAS-GKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALksesQNKIELLLQQHQDRiEQL 272
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  503 IEVLKESLTAKEQRAAILQTEVDALRLRLEE-KETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIE 581
Cdd:pfam15921  273 ISEHEVEITGLTEKASSARSQANSIQSQLEIiQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLV 352
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  582 NLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLkeqRDRDEREKQEeIDTYKKDLKDLREKV 661
Cdd:pfam15921  353 LANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRL---WDRDTGNSIT-IDHLRRELDDRNMEV 428
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  662 SLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKkAHEATLEA--RASPEMSDRIQQ 739
Cdd:pfam15921  429 QRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELT-AKKMTLESseRTVSDLTASLQE 507
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  740 LEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLtSRQVKDQNKKVANLKhkEQVEK---------KK 810
Cdd:pfam15921  508 KERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEAL-KLQMAEKDKVIEILR--QQIENmtqlvgqhgRT 584
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  811 SAQMLEEARRREDSLSDSSQQLQDSL---RKKDDRIEELE------------------EALRESVQITAEREMVLAQEES 869
Cdd:pfam15921  585 AGAMQVEKAQLEKEINDRRLELQEFKilkDKKDAKIRELEarvsdlelekvklvnagsERLRAVKDIKQERDQLLNEVKT 664
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  870 ART--------------NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKEThltnlraeRRKHLEEVLEMKQEAL 935
Cdd:pfam15921  665 SRNelnslsedyevlkrNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEG--------SDGHAMKVAMGMQKQI 736
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1720416765  936 LAAISEKDANIALLE-LSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMAD 989
Cdd:pfam15921  737 TAKRGQIDALQSKIQfLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGE 791
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
619-978 6.37e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.47  E-value: 6.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  619 EEALADKERTIERLKEQRDR--DEREKQEEIDTYKKDLKDLREKVSLlqgdlSEKEASLLDIKEHASSLASsglkKDSRL 696
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERlrREREKAERYQALLKEKREYEGYELL-----KEKEALERQKEAIERQLAS----LEEEL 253
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  697 KTLEIALEQKKEECLKMESQLKkaheaTLEARASPEMSDRIQQLEREISrykdessKAQTEVDRLLEILKEVENEKNDKD 776
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLE-----ELNKKIKDLGEEEQLRVKEKIG-------ELEAEIASLERSIAEKERELEDAE 321
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  777 KKIAELESLTSRQvkdqnkkvanlkhkeQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQI 856
Cdd:TIGR02169  322 ERLAKLEAEIDKL---------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  857 TAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEalL 936
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD--L 464
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1720416765  937 AAISEKdaniaLLELSSSKKKTQEEVAALKREKDRLVQQLKQ 978
Cdd:TIGR02169  465 SKYEQE-----LYDLKEEYDRVEKELSKLQRELAEAEAQARA 501
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
508-760 2.55e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.47  E-value: 2.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  508 ESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQL 587
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  588 RDKEKQmssLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDerekQEEIDTYKKDLKDLREKVSLLQGD 667
Cdd:COG4942    100 EAQKEE---LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPAR----REQAEELRADLAELAALRAELEAE 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  668 LSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKkaheatlearaspEMSDRIQQLEREISRY 747
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE-------------ELEALIARLEAEAAAA 239
                          250
                   ....*....|...
gi 1720416765  748 KDESSKAQTEVDR 760
Cdd:COG4942    240 AERTPAAGFAALK 252
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
736-964 6.82e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 6.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  736 RIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELEsltsRQVKDQNKKVANLKHKEQVEKKKSAQML 815
Cdd:COG4942     28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE----QELAALEAELAELEKEIAELRAELEAQK 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  816 EEARRREDSLSDSSQQlqdslrkkdDRIEELEEAlrESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESM 895
Cdd:COG4942    104 EELAELLRALYRLGRQ---------PPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720416765  896 KAKLSSTQQSLAEKETHLTNLRAERRKHLEEvLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAA 964
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLAR-LEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
564-780 8.57e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 8.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  564 DMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREK 643
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  644 QEEIDTYKKDLKDL-------REKVSLLQGDLSEKEASLLDIKEHASSLAS--SGLKKD-SRLKTLEIALEQKKEECLKM 713
Cdd:COG4942    100 EAQKEELAELLRALyrlgrqpPLALLLSPEDFLDAVRRLQYLKYLAPARREqaEELRADlAELAALRAELEAERAELEAL 179
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720416765  714 ESQLKKAHEATLEARAspEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIA 780
Cdd:COG4942    180 LAELEEERAALEALKA--ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
438-919 1.13e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.46  E-value: 1.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  438 NKVEQLKEELSSKDAQ--GEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDS--------KQHIEVLK 507
Cdd:COG4913    272 AELEYLRAALRLWFAQrrLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNggdrleqlEREIERLE 351
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  508 ESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKvnvlqkkienLQEQL 587
Cdd:COG4913    352 RELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD----------LRREL 421
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  588 RDKEKQMSSLKERVKS----LQADTTNTDTALTTLEEAL---------ADKERT----IERL-----------KEQRDR- 638
Cdd:COG4913    422 RELEAEIASLERRKSNiparLLALRDALAEALGLDEAELpfvgelievRPEEERwrgaIERVlggfaltllvpPEHYAAa 501
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  639 ----DEREKQEEIDTYK-KDLKDLREKVSLLQGDLSEKeaslLDIKEHA------SSLASSG----------LKKDSR-- 695
Cdd:COG4913    502 lrwvNRLHLRGRLVYERvRTGLPDPERPRLDPDSLAGK----LDFKPHPfrawleAELGRRFdyvcvdspeeLRRHPRai 577
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  696 -----LKTLEIALEQKKEECLKMESQLKKAHEATLEARAspemsDRIQQLEREISRYKDESSKAQTEVDRL------LEI 764
Cdd:COG4913    578 tragqVKGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALE-----AELAELEEELAEAEERLEALEAELDALqerreaLQR 652
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  765 LKEVENEKNDKDKKIAELESLTS--RQVKDQNKKVANLKhkeqvekkksaQMLEEARRREDSLSDSSQQLQDSLRKKDDR 842
Cdd:COG4913    653 LAEYSWDEIDVASAEREIAELEAelERLDASSDDLAALE-----------EQLEELEAELEELEEELDELKGEIGRLEKE 721
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720416765  843 IEELEEALRESVQITAEREMVLAQEEsaRTNAEKQVEELLMAmEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAE 919
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLEL--RALLEERFAAALGD-AVERELRENLEERIDALRARLNRAEEELERAMRA 795
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
445-986 1.22e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.34  E-value: 1.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  445 EELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDS----------KQHIEVLKESLTAK- 513
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAeemrarlaarKQELEEILHELESRl 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  514 ---EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 590
Cdd:pfam01576   85 eeeEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEF 164
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  591 EKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERT---IERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGD 667
Cdd:pfam01576  165 TSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGrqeLEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE 244
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  668 LSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREIsry 747
Cdd:pfam01576  245 LQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQEL--- 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  748 kdeSSKAQTEVDrllEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKH-KEQVEKKKSAQMLEEARRRED--S 824
Cdd:pfam01576  322 ---RSKREQEVT---ELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRnKANLEKAKQALESENAELQAElrT 395
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  825 LSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQ 904
Cdd:pfam01576  396 LQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE 475
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  905 SLAEKETHLTNLRA------ERRKHLEEVLEMKQEALLAAisEKDANIALLELSSSKKKTQEEVAA----------LKRE 968
Cdd:pfam01576  476 LLQEETRQKLNLSTrlrqleDERNSLQEQLEEEEEAKRNV--ERQLSTLQAQLSDMKKKLEEDAGTlealeegkkrLQRE 553
                          570
                   ....*....|....*...
gi 1720416765  969 KDRLVQQLKQQTQNRMKL 986
Cdd:pfam01576  554 LEALTQQLEEKAAAYDKL 571
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
344-906 3.35e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.06  E-value: 3.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  344 HHLESLLEQKEKENNMLREEMHR--RFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREE 421
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQinDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS 1208
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  422 EMKQMEVYRSHSKFM-KNKVEQLKEELSSKDAQGEELKKRAAGLqSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 500
Cdd:TIGR01612 1209 LEEVKGINLSYGKNLgKLFLEKIDEEKKKSEHMIKAMEAYIEDL-DEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDK 1287
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  501 QHievlkeSLTAKEQRAAILQTEVDALRLRLE-EKETMLNKKTKQIQDMAEEKGTQAGEIH----------------DLK 563
Cdd:TIGR01612 1288 DH------HIISKKHDENISDIREKSLKIIEDfSEESDINDIKKELQKNLLDAQKHNSDINlylneianiynilklnKIK 1361
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  564 DMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKslqadttnTDTALTTLEEALADKE--RTIERLKEQRDRDER 641
Cdd:TIGR01612 1362 KIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN--------LEECKSKIESTLDDKDidECIKKIKELKNHILS 1433
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  642 EkQEEIDTYKKDLKDLREKVSLLQGDL-------------------SEKEASLLDIKEHASSLASSGLKKDSRLKTLE-- 700
Cdd:TIGR01612 1434 E-ESNIDTYFKNADENNENVLLLFKNIemadnksqhilkikkdnatNDHDFNINELKEHIDKSKGCKDEADKNAKAIEkn 1512
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  701 -IALEQKKEECLKMesqLKKAHEATLEARASPEMSDRiQQLEREISRYKDESS-KAQTEVDRLLEILKE---VENE--KN 773
Cdd:TIGR01612 1513 kELFEQYKKDVTEL---LNKYSALAIKNKFAKTKKDS-EIIIKEIKDAHKKFIlEAEKSEQKIKEIKKEkfrIEDDaaKN 1588
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  774 DKDKKIA-----ELESLTSRQVKDQN-KKVAN--LKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEE 845
Cdd:TIGR01612 1589 DKSNKAAidiqlSLENFENKFLKISDiKKKINdcLKETESIEKKISSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKN 1668
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720416765  846 LEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV-KQELESMKAKLSSTQQSL 906
Cdd:TIGR01612 1669 IEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIAnKEEIESIKELIEPTIENL 1730
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
602-977 3.79e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.30  E-value: 3.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  602 KSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDErEKQEEIDTYKKDLKDLREKVSLLQGDLSEKEAslldIKEH 681
Cdd:PRK03918   165 KNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELE-EVLREINEISSELPELREELEKLEKEVKELEE----LKEE 239
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  682 ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRL 761
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRL 319
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  762 LEILKEVENEKNDKDKKIAELESLTSRQVKDQNKK-------------VANLKHKEQVEKKKSAQMLEEARRREDSLSDS 828
Cdd:PRK03918   320 EEEINGIEERIKELEEKEERLEELKKKLKELEKRLeeleerhelyeeaKAKKEELERLKKRLTGLTPEKLEKELEELEKA 399
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  829 SQQLQDSLRKKDDRIEELEealresvQITAEREMVLAQEESART-----NAEKQVEELLMAMEKVKQELESMKAKLSSTQ 903
Cdd:PRK03918   400 KEEIEEEISKITARIGELK-------KEIKELKKAIEELKKAKGkcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIE 472
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720416765  904 QSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKK---KTQEEVAALKREKDRLVQQLK 977
Cdd:PRK03918   473 EKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEeyeKLKEKLIKLKGEIKSLKKELE 549
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
474-662 3.91e-07

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 52.23  E-value: 3.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  474 ELSRKDTELLALQTKLETLtnqfsdsKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLnkktKQIQDMAEEKG 553
Cdd:COG1579     11 DLQELDSELDRLEHRLKEL-------PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEI----EEVEARIKKYE 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  554 TQAGEIHDLKDMldvkerkvNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAdttntdtALTTLEEALADKERTIERLK 633
Cdd:COG1579     80 EQLGNVRNNKEY--------EALQKEIESLKRRISDLEDEILELMERIEELEE-------ELAELEAELAELEAELEEKK 144
                          170       180
                   ....*....|....*....|....*....
gi 1720416765  634 EQRDRDEREKQEEIDTYKKDLKDLREKVS 662
Cdd:COG1579    145 AELDEELAELEAELEELEAEREELAAKIP 173
RBD-FIP pfam09457
FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of ...
1072-1112 5.73e-07

FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of Rab11-interacting proteins (FIPs). The Rab proteins constitute the largest family of small GTPases (>60 members in mammals). Among them Rab11 is a well characterized regulator of endocytic and recycling pathways. Rab11 associates with a broad range of post-Golgi organelles, including recycling endosomes.


Pssm-ID: 462805 [Multi-domain]  Cd Length: 41  Bit Score: 46.95  E-value: 5.73e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1720416765 1072 TQEQLQNELEKVEGDNAELQEFANTILQQIADHCPDILEQV 1112
Cdd:pfam09457    1 SRDELQDALQKQEEENRRLEDYIDNILLRIMEHNPSILEVP 41
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
390-1003 6.03e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.90  E-value: 6.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  390 KISSMERGLRDLEEEIQMLKSngalSSEEREEEMKQMEVYRShsKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIG 469
Cdd:TIGR00606  256 EIEHNLSKIMKLDNEIKALKS----RKKQMEKDNSELELKME--KVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELE 329
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  470 ---QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKE-----QRAAILQTEVD----ALRLRLEEKETM 537
Cdd:TIGR00606  330 klnKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLeldgfERGPFSERQIKnfhtLVIERQEDEAKT 409
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  538 LNKKTKQIQDMAEEKGTQAGEIHD-LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Cdd:TIGR00606  410 AAQLCADLQSKERLKQEQADEIRDeKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSK 489
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  617 TLEEALAD--KERTIERLKEQRDRDEREKQEEIDTYKKDL-KDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKD 693
Cdd:TIGR00606  490 AEKNSLTEtlKKEVKSLQNEKADLDRKLRKLDQEMEQLNHhTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYF 569
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  694 SRLKTLEIALEQKKEECLKMESQLKKaheatlearaspeMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEV---EN 770
Cdd:TIGR00606  570 PNKKQLEDWLHSKSKEINQTRDRLAK-------------LNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVcgsQD 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  771 EKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSA--QMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEE 848
Cdd:TIGR00606  637 EESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSccPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTES 716
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  849 ALResvQITAEREMVLAQEESARTNAEKQVEELlmamEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKH---LE 925
Cdd:TIGR00606  717 ELK---KKEKRRDEMLGLAPGRQSIIDLKEKEI----PELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAkvcLT 789
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720416765  926 EVLEMKQ-EALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFRSSRSNQ 1003
Cdd:TIGR00606  790 DVTIMERfQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE 868
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
389-602 6.32e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 6.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  389 SKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEI 468
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  469 GQVKQELSR--KDTELLALQTKLETLTNQ--FSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQ 544
Cdd:COG4942    100 EAQKEELAEllRALYRLGRQPPLALLLSPedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720416765  545 IQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVK 602
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
PRK01156 PRK01156
chromosome segregation protein; Provisional
288-896 6.38e-07

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 53.75  E-value: 6.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  288 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGL---SAKATEEDHERTRRLAEAEmhVHHLESLLEQKEKENNMLREEM 364
Cdd:PRK01156   164 LERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLeleNIKKQIADDEKSHSITLKE--IERLSIEYNNAMDDYNNLKSAL 241
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  365 HRrfenapdsakTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSngalsSEEREEEMKQMEVYRSHSKF-----MKNK 439
Cdd:PRK01156   242 NE----------LSSLEDMKNRYESEIKTAESDLSMELEKNNYYKE-----LEERHMKIINDPVYKNRNYIndyfkYKND 306
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  440 VEQLKEELSSKDAQ---GEELKKRAAGLQSEIGQVKQELSRKDtELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQR 516
Cdd:PRK01156   307 IENKKQILSNIDAEinkYHAIIKKLSVLQKDYNDYIKKKSRYD-DLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKN 385
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  517 AAILQTEVDALRLRLEEKETMLNKKTKQIqdmaeekgtqageihdlKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSS 596
Cdd:PRK01156   386 IERMSAFISEILKIQEIDPDAIKKELNEI-----------------NVKLQDISSKVSSLNQRIRALRENLDELSRNMEM 448
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  597 LKERVKslqADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEeIDTYKKDLKDLREKVSLLQ--------GDL 668
Cdd:PRK01156   449 LNGQSV---CPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKD-IDEKIVDLKKRKEYLESEEinksineyNKI 524
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  669 SEKEASLLDIKEHASSLASSGLKK---DSRLKTLEIA-LEQKKEECLKMESQLKKAHEATLEARaSPEMSDRIQQLErei 744
Cdd:PRK01156   525 ESARADLEDIKIKINELKDKHDKYeeiKNRYKSLKLEdLDSKRTSWLNALAVISLIDIETNRSR-SNEIKKQLNDLE--- 600
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  745 srykdesskaqtevDRLLEILKEVENEKNDKDKKIAELE----SLTSRQVKDQNKKVANLKHKEQVE--KKKSAQMLEea 818
Cdd:PRK01156   601 --------------SRLQEIEIGFPDDKSYIDKSIREIEneanNLNNKYNEIQENKILIEKLRGKIDnyKKQIAEIDS-- 664
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720416765  819 rrREDSLSDSSQQLQDSlrkkDDRIEELEEALRESVQITAEREmvlAQEESARTNaekqVEELLMAMEKVKQELESMK 896
Cdd:PRK01156   665 --IIPDLKEITSRINDI----EDNLKKSRKALDDAKANRARLE---STIEILRTR----INELSDRINDINETLESMK 729
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
532-975 6.50e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.57  E-value: 6.50e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  532 EEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNT 611
Cdd:pfam05483  229 EEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRS 308
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  612 DTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLK 691
Cdd:pfam05483  309 MSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQK 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  692 KDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILK----- 766
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKtseeh 468
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  767 ----------EVENEKND-------------KDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 823
Cdd:pfam05483  469 ylkevedlktELEKEKLKnieltahcdklllENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRD 548
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  824 SLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQ 903
Cdd:pfam05483  549 ELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAEN 628
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720416765  904 QSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQ 975
Cdd:pfam05483  629 KQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQH 700
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
414-949 9.70e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.19  E-value: 9.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  414 LSSEEREEEMKQMEVYRSHSKfmkNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLT 493
Cdd:pfam05483  247 IQITEKENKMKDLTFLLEESR---DKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIAT 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  494 NQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK------------------ETMLNKKTKQIQDMAEEKGTQ 555
Cdd:pfam05483  324 KTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELlrteqqrleknedqlkiiTMELQKKSSELEEMTKFKNNK 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  556 AGEIHDLKDMLDVKERKVNVlQKKIENLQEQLRDKEKQMSSLkervksLQADTTNTDTALTTLEEALADKERTIERLKEQ 635
Cdd:pfam05483  404 EVELEELKKILAEDEKLLDE-KKQFEKIAEELKGKEQELIFL------LQAREKEIHDLEIQLTAIKTSEEHYLKEVEDL 476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  636 RDRDEREKQEEIDTYKKDLKDLREKVSLLQgdlsEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKkeecLKMES 715
Cdd:pfam05483  477 KTELEKEKLKNIELTAHCDKLLLENKELTQ----EASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE----MNLRD 548
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  716 QLKKAHEATLEARasPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNK 795
Cdd:pfam05483  549 ELESVREEFIQKG--DEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSA 626
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  796 KVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEAlresvQITAEREMVLAQEESARtnAE 875
Cdd:pfam05483  627 ENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKA-----KAIADEAVKLQKEIDKR--CQ 699
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  876 KQVEELLMAMEKVKQ-----------ELESMKAKLSSTQQSLAEKETHLTNLRAERRKhLEEVLEMKQEALLAAISEKDA 944
Cdd:pfam05483  700 HKIAEMVALMEKHKHqydkiieerdsELGLYKNKEQEQSSAKAALEIELSNIKAELLS-LKKQLEIEKEEKEKLKMEAKE 778

                   ....*
gi 1720416765  945 NIALL 949
Cdd:pfam05483  779 NTAIL 783
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
473-670 1.66e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.61  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  473 QELSRKDTELLALQTKLETLtnqfsdskQHIEVLKESLTAKEQRAAILQTEVDALRLrlEEKETMLNKKTKQIQDMAEEK 552
Cdd:COG4913    235 DDLERAHEALEDAREQIELL--------EPIRELAERYAAARERLAELEYLRAALRL--WFAQRRLELLEAELEELRAEL 304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  553 GTQAGEIHDLKDMLDVKERKVNVLQ--------KKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAD 624
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEaqirgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAA 384
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1720416765  625 KERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSE 670
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
335-970 2.30e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.10  E-value: 2.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  335 RLAEAEMHVHHLESLLEQKEKENNMLREEMHRRFENAPDSAKTKALQTviemkdSKISSMERGLRDLEEEIqmlksngal 414
Cdd:pfam01576   20 RQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLA------ARKQELEEILHELESRL--------- 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  415 ssEEREEEMKQMEVYRshsKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVkqelsrkDTELLALQTKLETLTN 494
Cdd:pfam01576   85 --EEEEERSQQLQNEK---KKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKL-------EEDILLLEDQNSKLSK 152
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  495 QFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDmldvkerKVN 574
Cdd:pfam01576  153 ERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQE-------QIA 225
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  575 VLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQ---EEIDTYK 651
Cdd:pfam01576  226 ELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRdlgEELEALK 305
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  652 KDLKDLREKVSLLQGDLSEKEASLLDIKE--------HASSLASSGLKKDSRLKTLEIALEQKK--------------EE 709
Cdd:pfam01576  306 TELEDTLDTTAAQQELRSKREQEVTELKKaleeetrsHEAQLQEMRQKHTQALEELTEQLEQAKrnkanlekakqaleSE 385
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  710 CLKMESQLKKAHEATLEARAS--------PEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAE 781
Cdd:pfam01576  386 NAELQAELRTLQQAKQDSEHKrkklegqlQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSS 465
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  782 LESL---TSRQVKDQNKKVANLKHK-EQVEKKKSAQM-----LEEARRR-EDSLSDSSQQLQDSLRKKDDR---IEELEE 848
Cdd:pfam01576  466 LESQlqdTQELLQEETRQKLNLSTRlRQLEDERNSLQeqleeEEEAKRNvERQLSTLQAQLSDMKKKLEEDagtLEALEE 545
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  849 A-------LRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERR 921
Cdd:pfam01576  546 GkkrlqreLEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERD 625
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 1720416765  922 KHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKD 970
Cdd:pfam01576  626 RAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKD 674
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
464-689 2.58e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 50.98  E-value: 2.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  464 LQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEeketmlnkktK 543
Cdd:COG3883     21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELG----------E 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  544 QIQDMAEEKGT--------QAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTAL 615
Cdd:COG3883     91 RARALYRSGGSvsyldvllGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720416765  616 TTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSG 689
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
570-852 3.03e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 3.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  570 ERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEAL--ADKERTIERLKEQRDRderekqeeI 647
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELER--------L 680
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  648 DTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLassglkkDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEA 727
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRL-------EKELEQAEEELDELQDRLEAAEDLARLELRALLEE 753
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  728 RASPEMSDRI-----QQLEREISRYKDESSKAQTEVDRLL-EILKEVENEKNDKDKKIAELESLtsRQVKDQNKKVANLK 801
Cdd:COG4913    754 RFAAALGDAVerelrENLEERIDALRARLNRAEEELERAMrAFNREWPAETADLDADLESLPEY--LALLDRLEEDGLPE 831
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720416765  802 HKEQVEKKKSAQMleearrrEDSLSDSSQQLQDSLRKKDDRIEELEEALRE 852
Cdd:COG4913    832 YEERFKELLNENS-------IEFVADLLSKLRRAIREIKERIDPLNDSLKR 875
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
398-820 3.56e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.31  E-value: 3.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  398 LRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSR 477
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  478 KDT--ELLALQTKLETLTNQFSDSKQHIEVLKEsltaKEQRAAILQTEVDALRLRLEEKETMLNKKT-KQIQDMAEEKGT 554
Cdd:COG4717    128 LPLyqELEALEAELAELPERLEELEERLEELRE----LEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEE 203
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  555 QAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQ----------------------------------------- 593
Cdd:COG4717    204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEerlkearlllliaaallallglggsllsliltiagvlflvl 283
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  594 ----MSSLKERVKSLQADTTNTDTALTTLEEALADKErtIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDls 669
Cdd:COG4717    284 gllaLLFLLLAREKASLGKEAEELQALPALEELEEEE--LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL-- 359
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  670 EKEASLLDIKEHASSLASSGLKKD-----SRLKTLEiALEQKKEECLKMESQL---KKAHEATLEARASPEMSDRIQQLE 741
Cdd:COG4717    360 EEELQLEELEQEIAALLAEAGVEDeeelrAALEQAE-EYQELKEELEELEEQLeelLGELEELLEALDEEELEEELEELE 438
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  742 REISRYKDESSKAQTEVDRLLEILKEVENEkNDKDKKIAELESLTSRqVKDQNKKVANLK--------HKEQVEKKKSAQ 813
Cdd:COG4717    439 EELEELEEELEELREELAELEAELEQLEED-GELAELLQELEELKAE-LRELAEEWAALKlalelleeAREEYREERLPP 516

                   ....*..
gi 1720416765  814 MLEEARR 820
Cdd:COG4717    517 VLERASE 523
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
619-1034 4.16e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.13  E-value: 4.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  619 EEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKT 698
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIE 261
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  699 LEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQL---------EREISRYKDESSKAQTEVDRLLEILKEVE 769
Cdd:pfam02463  262 KEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLklerrkvddEEKLKESEKEKKKAEKELKKEKEEIEELE 341
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  770 NEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEA 849
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  850 LRESVQITAEREMVLAQEESARTNAEKQVEELlmamekVKQELESMKAKLSSTQQSLAEKETHLTnlrAERRKHLEEVLE 929
Cdd:pfam02463  422 KEEKKEELEILEEEEESIELKQGKLTEEKEEL------EKQELKLLKDELELKKSEDLLKETQLV---KLQEQLELLLSR 492
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  930 MKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFRSSRSNQTNHKPS 1009
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTE 572
                          410       420
                   ....*....|....*....|....*
gi 1720416765 1010 PDQIIQPLLELDQNRSKLKLYIGHL 1034
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVL 597
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
530-926 6.43e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 6.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  530 RLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKE--RKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAD 607
Cdd:COG4717     89 EYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEEL 168
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  608 TTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEH------ 681
Cdd:COG4717    169 EAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEerlkea 248
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  682 ----------ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDES 751
Cdd:COG4717    249 rlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL 328
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  752 SKAQTEVDRLLEILKEVENEKNDKDKKIAELESltSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQ 831
Cdd:COG4717    329 GLPPDLSPEELLELLDRIEELQELLREAEELEE--ELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEE 406
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  832 LQDSLRKKDDRIEELEEALREsvqitAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKaklssTQQSLAEKET 911
Cdd:COG4717    407 LEEQLEELLGELEELLEALDE-----EELEEELEELEEELEELEEELEELREELAELEAELEQLE-----EDGELAELLQ 476
                          410
                   ....*....|....*
gi 1720416765  912 HLTNLRAERRKHLEE 926
Cdd:COG4717    477 ELEELKAELRELAEE 491
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
735-964 6.61e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.83  E-value: 6.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  735 DRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELEsltsRQVKDQNKKVANLKHKEQVEKKKSAQM 814
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQ----AEIDKLQAEIAEAEAEIEERREELGER 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  815 LEEARRREDSLSD-----SSQQLQDSLrkkdDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELlmamEKVK 889
Cdd:COG3883     92 ARALYRSGGSVSYldvllGSESFSDFL----DRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAEL----EALK 163
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720416765  890 QELESMKAKLsstQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAA 964
Cdd:COG3883    164 AELEAAKAEL---EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
725-932 6.72e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 6.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  725 LEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEIlKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKE 804
Cdd:COG4913    218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPI-RELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAE 296
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  805 ----QVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKD-DRIEELEEALRESVQITAEREMVLAQ-EESART---NAE 875
Cdd:COG4913    297 leelRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARlEALLAAlglPLP 376
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720416765  876 KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 932
Cdd:COG4913    377 ASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
425-606 7.70e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 7.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  425 QMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKR---------AAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQ 495
Cdd:COG3206    169 RREEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvdlseeAKLLLQQLSELESQLAEARAELAEAEARLAALRAQ 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  496 FSDSKQHIEVLKES--LTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEI-HDLKDMLDVKERK 572
Cdd:COG3206    249 LGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRIlASLEAELEALQAR 328
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1720416765  573 VNVLQKKIENLQEQLR---DKEKQMSSLKERVKSLQA 606
Cdd:COG3206    329 EASLQAQLAQLEARLAelpELEAELRRLEREVEVARE 365
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
501-939 8.09e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 8.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  501 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKgtqagEIHDLKDMLDVKERKVNVLQKKI 580
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQ-----ELEALEAELAELPERLEELEERL 155
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  581 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREK 660
Cdd:COG4717    156 EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE 235
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  661 VSLLQ--GDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQ 738
Cdd:COG4717    236 LEAAAleERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEE 315
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  739 QLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESltSRQVKDQNKKVANLKHKEQVEKKKS-AQMLEE 817
Cdd:COG4717    316 LEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE--ELQLEELEQEIAALLAEAGVEDEEElRAALEQ 393
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  818 ARRRedslsdssQQLQDSLRKKDDRIEELEEALRESVQITAEREMvlaqeesartnaEKQVEELLMAMEKVKQELESMKA 897
Cdd:COG4717    394 AEEY--------QELKEELEELEEQLEELLGELEELLEALDEEEL------------EEELEELEEELEELEEELEELRE 453
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1720416765  898 KLSSTQQSL--AEKETHLTNLRAERRKHLEEVLEMKQEALLAAI 939
Cdd:COG4717    454 ELAELEAELeqLEEDGELAELLQELEELKAELRELAEEWAALKL 497
PRK01156 PRK01156
chromosome segregation protein; Provisional
529-972 1.02e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 49.90  E-value: 1.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  529 LRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADT 608
Cdd:PRK01156   169 DKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLE 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  609 TNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEID-------------TYKKDLKDLREKVSLLQGDLSEKEASL 675
Cdd:PRK01156   249 DMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDpvyknrnyindyfKYKNDIENKKQILSNIDAEINKYHAII 328
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  676 LDIKEhASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKaheatlearaspemsdrIQQLEREISRYKDESSKAQ 755
Cdd:PRK01156   329 KKLSV-LQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKS-----------------IESLKKKIEEYSKNIERMS 390
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  756 TEVDRLLEIlkevenEKNDKDKKIAELESLtSRQVKDQNKKVANLkhkeQVEKKKSAQMLEEARRREDSLS--------- 826
Cdd:PRK01156   391 AFISEILKI------QEIDPDAIKKELNEI-NVKLQDISSKVSSL----NQRIRALRENLDELSRNMEMLNgqsvcpvcg 459
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  827 -----DSSQQLQDSLRKKDDRIEE-LEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 900
Cdd:PRK01156   460 ttlgeEKSNHIINHYNEKKSRLEEkIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKIN 539
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720416765  901 stqqSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEkdanIALLELSSSKKKTQEEVAALKREKDRL 972
Cdd:PRK01156   540 ----ELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAV----ISLIDIETNRSRSNEIKKQLNDLESRL 603
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
577-878 1.13e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.74  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  577 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLK-EQRDRD-EREKQEEIDTYKKDL 654
Cdd:pfam17380  298 QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRqEERKRElERIRQEEIAMEISRM 377
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  655 KDLrEKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMS 734
Cdd:pfam17380  378 REL-ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQ 456
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  735 DRIQQLEReISRYKDESSKAQTEVDRLLEILKEVENEKndkdKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSaqM 814
Cdd:pfam17380  457 ERQQQVER-LRQQEEERKRKKLELEKEKRDRKRAEEQR----RKILEKELEERKQAMIEEERKRKLLEKEMEERQKA--I 529
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720416765  815 LEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV 878
Cdd:pfam17380  530 YEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEA 593
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
621-858 1.23e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  621 ALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLE 700
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  701 IALEQKKEEclkMESQLKKAHEAtleARASPEM----SDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKD 776
Cdd:COG4942     97 AELEAQKEE---LAELLRALYRL---GRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  777 KKIAELESLTSRQVKDQNKKvanlkhkeQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQI 856
Cdd:COG4942    171 AERAELEALLAELEEERAAL--------EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242

                   ..
gi 1720416765  857 TA 858
Cdd:COG4942    243 TP 244
46 PHA02562
endonuclease subunit; Provisional
593-835 1.55e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 48.86  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  593 QMSSL-KERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEK 671
Cdd:PHA02562   167 EMDKLnKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNL 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  672 EASLLDIKEHASSLASSGLKKDSRLKTL--EIALEQKKEECLKMESQLKKAHEATLEARAS-PEMSDRIQQLEREISRYK 748
Cdd:PHA02562   247 VMDIEDPSAALNKLNTAAAKIKSKIEQFqkVIKMYEKGGVCPTCTQQISEGPDRITKIKDKlKELQHSLEKLDTAIDELE 326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  749 DESSKAQTEVDRLLEILKEVENEK------NDKDKKI-AELESLTSrQVKDQNKKVANLKHKEQVEKKKSAQMLEEarrr 821
Cdd:PHA02562   327 EIMDEFNEQSKKLLELKNKISTNKqslitlVDKAKKVkAAIEELQA-EFVDNAEELAKLQDELDKIVKTKSELVKE---- 401
                          250
                   ....*....|....
gi 1720416765  822 EDSLSDSSQQLQDS 835
Cdd:PHA02562   402 KYHRGIVTDLLKDS 415
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
420-986 1.63e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.20  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  420 EEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDS 499
Cdd:pfam02463  152 PERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDY 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  500 KQHIEVLKESLT----AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNV 575
Cdd:pfam02463  232 LKLNEERIDLLQellrDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD 311
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  576 LQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKK--- 652
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSaak 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  653 -----------------DLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMES 715
Cdd:pfam02463  392 lkeeelelkseeekeaqLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  716 QLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAqTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNK 795
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLK-VLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVI 550
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  796 KVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAE 875
Cdd:pfam02463  551 VEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILK 630
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  876 KQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSK 955
Cdd:pfam02463  631 DTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKE 710
                          570       580       590
                   ....*....|....*....|....*....|.
gi 1720416765  956 KKTQEEVAALKREKDRLVQQLKQQTQNRMKL 986
Cdd:pfam02463  711 ELKKLKLEAEELLADRVQEAQDKINEELKLL 741
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
464-792 1.64e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 48.36  E-value: 1.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  464 LQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Cdd:COG4372     43 LQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQK 122
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  544 QIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERvkSLQADTTNTDTALTTLEEALA 623
Cdd:COG4372    123 ERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEA--EAEQALDELLKEANRNAEKEE 200
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  624 DKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIAL 703
Cdd:COG4372    201 ELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEI 280
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  704 EQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELE 783
Cdd:COG4372    281 AALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLS 360

                   ....*....
gi 1720416765  784 SLTSRQVKD 792
Cdd:COG4372    361 KGAEAGVAD 369
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
757-989 2.18e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 2.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  757 EVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKV---ANLKHKEQVE-------KKKSAQMLEEARRREDSLS 826
Cdd:TIGR02169  171 KKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAEryqALLKEKREYEgyellkeKEALERQKEAIERQLASLE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  827 DSSQQLQDSLRKKDDRIEELEEALRE---SVQITAEREMVLAQE-----ESARTNAEKQVEELLMAMEKVKQELESMKAK 898
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEElnkKIKDLGEEEQLRVKEkigelEAEIASLERSIAEKERELEDAEERLAKLEAE 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  899 LSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQE--ALLAAISEKDANIALL--ELSSSKKK---TQEEVAALKREKDR 971
Cdd:TIGR02169  331 IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEleDLRAELEEVDKEFAETrdELKDYREKlekLKREINELKRELDR 410
                          250
                   ....*....|....*...
gi 1720416765  972 LVQQLKQQTQNRMKLMAD 989
Cdd:TIGR02169  411 LQEELQRLSEELADLNAA 428
PRK12704 PRK12704
phosphodiesterase; Provisional
772-968 2.68e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 48.24  E-value: 2.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  772 KNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKsaqmlEEARRRedslsdssQQLQDSLRKKDDRIEELEEALR 851
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKE-----EIHKLR--------NEFEKELRERRNELQKLEKRLL 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  852 EsvqitaeREMVLaqeesartnaEKQVEELlmamEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMK 931
Cdd:PRK12704    93 Q-------KEENL----------DRKLELL----EKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLT 151
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1720416765  932 QEallaaisekDANIALLElsSSKKKTQEEVAALKRE 968
Cdd:PRK12704   152 AE---------EAKEILLE--KVEEEARHEAAVLIKE 177
PRK09039 PRK09039
peptidoglycan -binding protein;
473-605 2.94e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 47.65  E-value: 2.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  473 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEK 552
Cdd:PRK09039    46 REISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQEL 125
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720416765  553 GTQAGEIHDlkdmldvKERKVNVLQKKIENLQEQL------------RDKEKQM----------SSLKERVKSLQ 605
Cdd:PRK09039   126 DSEKQVSAR-------ALAQVELLNQQIAALRRQLaaleaaldasekRDRESQAkiadlgrrlnVALAQRVQELN 193
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
732-986 4.68e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 4.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  732 EMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSR--QVKDQNKKVANLKHKEQVEKK 809
Cdd:PRK03918   173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEvkELEELKEEIEELEKELESLEG 252
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  810 KSAQMLEEARRREDSLSDSSQQLQDsLRKKDDRIEELEEALRESVQITAEREMVLaQEESARTNAEKQVEELLMAMEKVK 889
Cdd:PRK03918   253 SKRKLEEKIRELEERIEELKKEIEE-LEEKVKELKELKEKAEEYIKLSEFYEEYL-DELREIEKRLSRLEEEINGIEERI 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  890 QELESMKAKLSSTQQSLAEKETHLTNLRaERRKHLEEVLEMKQE-----ALLAAISEKDANIALLELSSSKKKTQEEVAA 964
Cdd:PRK03918   331 KELEEKEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEElerlkKRLTGLTPEKLEKELEELEKAKEEIEEEISK 409
                          250       260
                   ....*....|....*....|..
gi 1720416765  965 LKREKDRLVQQLKQQTQNRMKL 986
Cdd:PRK03918   410 ITARIGELKKEIKELKKAIEEL 431
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
436-626 5.25e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 5.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  436 MKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSD----------SKQHIEV 505
Cdd:COG3883     28 LQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraralyrsggSVSYLDV 107
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  506 LKESLTAKE--QRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENL 583
Cdd:COG3883    108 LLGSESFSDflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQL 187
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1720416765  584 QEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKE 626
Cdd:COG3883    188 SAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
682-900 5.46e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 5.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  682 ASSLASSGLKKDSRLKTLEiALEQKKEECLKMESQLKKAHEATLEARAspEMSDRIQQLEREISRYKDESSKAQTEVDRL 761
Cdd:COG4942     12 ALAAAAQADAAAEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLA--ALERRIAALARRIRALEQELAALEAELAEL 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  762 LEILKEVENEKNDKDKKIAELesLTSRQVKDQNKKVANLKHKEQVEK------------KKSAQMLEEARRREDSLSDSS 829
Cdd:COG4942     89 EKEIAELRAELEAQKEELAEL--LRALYRLGRQPPLALLLSPEDFLDavrrlqylkylaPARREQAEELRADLAELAALR 166
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720416765  830 QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 900
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
619-792 5.58e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.16  E-value: 5.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  619 EEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEkeaslldikehasslassglkKDSRLKT 698
Cdd:COG2433    387 EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEE---------------------KDERIER 445
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  699 LEIALEQKKEEclkMESQLKKAHEATLEARaspemsdRIQQLEREISRYKDESSKAQTEVDRLLEILKEVEnekndKDKK 778
Cdd:COG2433    446 LERELSEARSE---ERREIRKDREISRLDR-------EIERLERELEEERERIEELKRKLERLKELWKLEH-----SGEL 510
                          170
                   ....*....|....*.
gi 1720416765  779 IA--ELESLTSRQVKD 792
Cdd:COG2433    511 VPvkVVEKFTKEAIRR 526
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
334-671 7.14e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 7.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  334 RRLAEAEMHVHHLESLLEQKEKEnnmlREEMHRRFEnapdsaktkALQTVIEMKDSKI--SSMERGLRDLEEEIQMLKSN 411
Cdd:COG4913    617 AELAELEEELAEAEERLEALEAE----LDALQERRE---------ALQRLAEYSWDEIdvASAEREIAELEAELERLDAS 683
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  412 GAlsseereeemkqmevyrshskfmknKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLET 491
Cdd:COG4913    684 SD-------------------------DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA 738
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  492 LTNQFS-DSKQHIEVLKESLTAKEQRAAI---LQTEVDALRLRLEEKETMLNKKTKQIQ----DMAEEKGTQAGEIHDLK 563
Cdd:COG4913    739 AEDLARlELRALLEERFAAALGDAVERELrenLEERIDALRARLNRAEEELERAMRAFNrewpAETADLDADLESLPEYL 818
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  564 DMLDvkerkvNVLQKKIENLQEQLRDKEKQMSslKERVKSLQAdttntdtaltTLEEALADKERTIERLKE-------QR 636
Cdd:COG4913    819 ALLD------RLEEDGLPEYEERFKELLNENS--IEFVADLLS----------KLRRAIREIKERIDPLNDslkripfGP 880
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1720416765  637 DRD-----EREKQEEIDTYKKDLKDLREKVSLLQGDLSEK 671
Cdd:COG4913    881 GRYlrleaRPRPDPEVREFRQELRAVTSGASLFDEELSEA 920
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
455-976 8.83e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 8.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  455 EELKKRAAGLQSEIGQVKQELSRkdTELLALQTKLETLtnqfsdsKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE- 533
Cdd:COG4913    258 RELAERYAAARERLAELEYLRAA--LRLWFAQRRLELL-------EAELEELRAELARLEAELERLEARLDALREELDEl 328
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  534 KETMLNKKTKQIQDMAEEkgtqageIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTdt 613
Cdd:COG4913    329 EAQIRGNGGDRLEQLERE-------IERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEE-- 399
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  614 alttlEEALADKERTIERLKEQRDRDEREKQEEID-------TYKKDLKDLREkvsLLQGDLSEKEAS------LLDIKE 680
Cdd:COG4913    400 -----LEALEEALAEAEAALRDLRRELRELEAEIAslerrksNIPARLLALRD---ALAEALGLDEAElpfvgeLIEVRP 471
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  681 HAS-----------SLASSGLKKDSRLKTLEIALEQKKeecLKMESQLKKAHEATLEARASPEMSDRI-QQLEREISRYK 748
Cdd:COG4913    472 EEErwrgaiervlgGFALTLLVPPEHYAAALRWVNRLH---LRGRLVYERVRTGLPDPERPRLDPDSLaGKLDFKPHPFR 548
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  749 DEsskAQTEVDRLLEILKeVENEkndkdkkiAELE----SLT---------SRQVKDQNKKVA--------NLKHKEQVE 807
Cdd:COG4913    549 AW---LEAELGRRFDYVC-VDSP--------EELRrhprAITragqvkgngTRHEKDDRRRIRsryvlgfdNRAKLAALE 616
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  808 KKksAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQI-TAEREmvLAQEESARTNAEK---QVEELLM 883
Cdd:COG4913    617 AE--LAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVaSAERE--IAELEAELERLDAssdDLAALEE 692
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  884 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKH---LEEVLEMKQEALLAAISEKDANIALLELSSSKKKT-Q 959
Cdd:COG4913    693 QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELqdrLEAAEDLARLELRALLEERFAAALGDAVERELRENlE 772
                          570
                   ....*....|....*..
gi 1720416765  960 EEVAALKREKDRLVQQL 976
Cdd:COG4913    773 ERIDALRARLNRAEEEL 789
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
278-978 1.66e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 1.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  278 AKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKEN 357
Cdd:TIGR00606  418 QSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTE 497
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  358 NMLREEMHRRFENAPDSAKTKALQTVIEMKD------SKISSMERGLRDLEEEIQMLKSNGAlsseereEEMKQMEVYRS 431
Cdd:TIGR00606  498 TLKKEVKSLQNEKADLDRKLRKLDQEMEQLNhhtttrTQMEMLTKDKMDKDEQIRKIKSRHS-------DELTSLLGYFP 570
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  432 HSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQfSDSKQHIEVLKESLT 511
Cdd:TIGR00606  571 NKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIE 649
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  512 AKEQRAAILQTEVDALRLRLEEketmLNKKTKQIQDMAEEKGTQAGEIHDLKDMLdvkERKVNVLQKKIENLQEQLRDKE 591
Cdd:TIGR00606  650 KSSKQRAMLAGATAVYSQFITQ----LTDENQSCCPVCQRVFQTEAELQEFISDL---QSKLRLAPDKLKSTESELKKKE 722
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  592 KQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEqrDRDEREKQ-EEIDTYKKDLKDLREKVSLLQGDLSE 670
Cdd:TIGR00606  723 KRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN--DIEEQETLlGTIMPEEESAKVCLTDVTIMERFQME 800
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  671 KEASLLDIKEHASSLASSGLKKDSRlktleiALEQKKEEclKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDE 750
Cdd:TIGR00606  801 LKDVERKIAQQAAKLQGSDLDRTVQ------QVNQEKQE--KQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSE 872
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  751 SSKAQTEVDRLLEILKEVEnekndkdKKIAELESLTsRQVKDQNKKVANLkhkEQVEKKKSAQMLEEARRREDSLSDSSQ 830
Cdd:TIGR00606  873 KLQIGTNLQRRQQFEEQLV-------ELSTEVQSLI-REIKDAKEQDSPL---ETFLEKDQQEKEELISSKETSNKKAQD 941
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  831 QLQDsLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAekQVEELLMAMEKVKQELESMKAKLSSTQQ------ 904
Cdd:TIGR00606  942 KVND-IKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNA--QLEECEKHQEKINEDMRLMRQDIDTQKIqerwlq 1018
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720416765  905 ---SLAEKETHLTNLRAERRKHLEEVLEMKqeallaaisekdaniaLLELSSSKKKTQEEVAALKREKDRLVQQLKQ 978
Cdd:TIGR00606 1019 dnlTLRKRENELKEVEEELKQHLKEMGQMQ----------------VLQMKQEHQKLEENIDLIKRNHVLALGRQKG 1079
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
579-848 1.70e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 45.81  E-value: 1.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  579 KIENLQEQLRDKEKQMSSLKER-VKSLQADTTNTDTALTTLEEALADKER-TIERLKEQRDRDEREKQEEIDTYKKdlKD 656
Cdd:PTZ00108  1103 KVEKLNAELEKKEKELEKLKNTtPKDMWLEDLDKFEEALEEQEEVEEKEIaKEQRLKSKTKGKASKLRKPKLKKKE--KK 1180
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  657 LREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKK---DSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEM 733
Cdd:PTZ00108  1181 KKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKksnSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEF 1260
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  734 SDRIQQLEREISRY-------KDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVA-NLKHKEQ 805
Cdd:PTZ00108  1261 SSDDLSKEGKPKNApkrvsavQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTArKKKSKTR 1340
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1720416765  806 VEKKKSAQMLEEARRREDSLSDSSqQLQDSLRKKDDRIEELEE 848
Cdd:PTZ00108  1341 VKQASASQSSRLLRRPRKKKSDSS-SEDDDDSEVDDSEDEDDE 1382
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
713-950 2.29e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 2.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  713 MESQLKKAHEATLEARAS-----PEMSDRIQQLEREISRYKDESS--KAQTEVDRLLEILKEVENEKNDKDKKIAELESL 785
Cdd:COG3206    162 LEQNLELRREEARKALEFleeqlPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEARAELAEAEAR 241
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  786 ---TSRQVKDQNKKVANLKHKEQVEKKKSAqmLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEalresvQITAEREM 862
Cdd:COG3206    242 laaLRAQLGSGPDALPELLQSPVIQQLRAQ--LAELEAELAELSARYTPNHPDVIALRAQIAALRA------QLQQEAQR 313
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  863 VLAQEESARTNAEKQVEELlmamekvKQELESMKAKLsstqQSLAEKETHLTNLRAER---RKHLEEVLEMKQEALLAAi 939
Cdd:COG3206    314 ILASLEAELEALQAREASL-------QAQLAQLEARL----AELPELEAELRRLEREVevaRELYESLLQRLEEARLAE- 381
                          250
                   ....*....|.
gi 1720416765  940 SEKDANIALLE 950
Cdd:COG3206    382 ALTVGNVRVID 392
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
436-596 2.30e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 2.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  436 MKNKVEQLkEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQ 515
Cdd:COG1579      2 MPEDLRAL-LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  516 R---------AAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQ 586
Cdd:COG1579     81 QlgnvrnnkeYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEE 160
                          170
                   ....*....|
gi 1720416765  587 LRDKEKQMSS 596
Cdd:COG1579    161 LEAEREELAA 170
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
277-530 2.33e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 2.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  277 QAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQskglsaKATEEDHERTRRLAEAEMHVHHLESLLEQKEKE 356
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA------ALERRIAALARRIRALEQELAALEAELAELEKE 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  357 NNMLREEMHRRFENapdsaktkalqtviemkdskissMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFM 436
Cdd:COG4942     92 IAELRAELEAQKEE-----------------------LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPAR 148
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  437 KNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQR 516
Cdd:COG4942    149 REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
                          250
                   ....*....|....
gi 1720416765  517 AAILQTEVDALRLR 530
Cdd:COG4942    229 IARLEAEAAAAAER 242
46 PHA02562
endonuclease subunit; Provisional
564-783 2.46e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 2.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  564 DMLDVKE-RKVNVLQK-KIENLQEQLRDKEKQMSSLKERVK-------SLQADTTNTDTALTTLEEALADKERTIERLKE 634
Cdd:PHA02562   158 DLLDISVlSEMDKLNKdKIRELNQQIQTLDMKIDHIQQQIKtynknieEQRKKNGENIARKQNKYDELVEEAKTIKAEIE 237
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  635 QRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLS--EKEASLL-----------DIKEHASSLAssglKKDSRLKTLEI 701
Cdd:PHA02562   238 ELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEqfQKVIKMYekggvcptctqQISEGPDRIT----KIKDKLKELQH 313
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  702 ALEQKKEECLKMESQLKKAHEATLEARaspEMSDRIQQLEREISRYKDESSKAQTEVDRLL-------EILKEVENEKND 774
Cdd:PHA02562   314 SLEKLDTAIDELEEIMDEFNEQSKKLL---ELKNKISTNKQSLITLVDKAKKVKAAIEELQaefvdnaEELAKLQDELDK 390

                   ....*....
gi 1720416765  775 KDKKIAELE 783
Cdd:PHA02562   391 IVKTKSELV 399
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
756-942 2.84e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 2.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  756 TEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARrredslsdssQQLQDS 835
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEL----------EALEAE 140
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  836 LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEkvkQELESMKAKLSSTQQSLAEKETHLTN 915
Cdd:COG4717    141 LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEE 217
                          170       180
                   ....*....|....*....|....*..
gi 1720416765  916 LRAERRKHLEEVLEMKQEALLAAISEK 942
Cdd:COG4717    218 AQEELEELEEELEQLENELEAAALEER 244
PRK12704 PRK12704
phosphodiesterase; Provisional
718-907 3.70e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.38  E-value: 3.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  718 KKAHEATLEARaspemsDRIQQLEREISRYKDEsskAQTEV-DRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKK 796
Cdd:PRK12704    31 AKIKEAEEEAK------RILEEAKKEAEAIKKE---ALLEAkEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  797 VANLKHKEQ-VEKKKsaqmlEEARRREDSLSDSSQQLQdslRKKDDRIEELEEAlresVQITAE--REMVLAQ-EESART 872
Cdd:PRK12704   102 LELLEKREEeLEKKE-----KELEQKQQELEKKEEELE---ELIEEQLQELERI----SGLTAEeaKEILLEKvEEEARH 169
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1720416765  873 NAEKQVEEllmAMEKVKQELEsMKAK--LSSTQQSLA 907
Cdd:PRK12704   170 EAAVLIKE---IEEEAKEEAD-KKAKeiLAQAIQRCA 202
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
192-838 3.76e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 3.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  192 PELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQdsssrtgepcvaelteENFQRLH 271
Cdd:TIGR00618  297 AHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQ----------------EIHIRDA 360
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  272 AEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKglsaKATEEDHERTRRLAEAEMHVHHLESLLE 351
Cdd:TIGR00618  361 HEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQRE----QATIDTRTSAFRDLQGQLAHAKKQQELQ 436
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  352 QKEKEnnmlreemhrrfenapdsAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSseEREEEMKQMEVYRs 431
Cdd:TIGR00618  437 QRYAE------------------LCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIH--LQETRKKAVVLAR- 495
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  432 hskfmknKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKqeLSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 511
Cdd:TIGR00618  496 -------LLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRR--MQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQ 566
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  512 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMldvkerkvnvLQKKIENLQEQLRDKE 591
Cdd:TIGR00618  567 EIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRK----------LQPEQDLQDVRLHLQQ 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  592 KQMSslkERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEK 671
Cdd:TIGR00618  637 CSQE---LALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHI 713
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  672 EASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE-ATLEARASPEMSDRIQQLEREISRYKDE 750
Cdd:TIGR00618  714 EEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFnNNEEVTAALQTGAELSHLAAEIQFFNRL 793
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  751 SSKAQTEvdrlLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQ 830
Cdd:TIGR00618  794 REEDTHL----LKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQA 869

                   ....*...
gi 1720416765  831 QLQDSLRK 838
Cdd:TIGR00618  870 KIIQLSDK 877
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
735-985 4.42e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 44.30  E-value: 4.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  735 DRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENekndkdkkiaelesltsrqvkdqnkkvANLKHKEQVEkkksaqm 814
Cdd:COG0497    165 RAWRALKKELEELRADEAERARELDLLRFQLEELEA---------------------------AALQPGEEEE------- 210
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  815 LEEARRRedsLSdSSQQLQDSLRKKDDRIEELEEALRESVQiTAEREMV-LAQEESARTNAEKQVEELLMAMEKVKQELE 893
Cdd:COG0497    211 LEEERRR---LS-NAEKLREALQEALEALSGGEGGALDLLG-QALRALErLAEYDPSLAELAERLESALIELEEAASELR 285
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  894 SMKAKLSSTQQSLAEKETHLTNLRAERRKH---LEEVLEMKQEAL--LAAISEKDANIALLElssskkktqEEVAALKRE 968
Cdd:COG0497    286 RYLDSLEFDPERLEEVEERLALLRRLARKYgvtVEELLAYAEELRaeLAELENSDERLEELE---------AELAEAEAE 356
                          250
                   ....*....|....*..
gi 1720416765  969 KDRLVQQLkqqTQNRMK 985
Cdd:COG0497    357 LLEAAEKL---SAARKK 370
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
578-978 4.58e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 4.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  578 KKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTAlttlEEALADKERTIERLkeQRDRDEREKQEEIDTYKKDLKDL 657
Cdd:COG4717     64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEEL----EEELEELEAELEEL--REELEKLEKLLQLLPLYQELEAL 137
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  658 REKVSLLQGDLSEKEASLLDIKEhasslassglkKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEaraspEMSDRI 737
Cdd:COG4717    138 EAELAELPERLEELEERLEELRE-----------LEEELEELEAELAELQEELEELLEQLSLATEEELQ-----DLAEEL 201
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  738 QQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKK---------------IAELESLTSRQ------------- 789
Cdd:COG4717    202 EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEerlkearlllliaaaLLALLGLGGSLlsliltiagvlfl 281
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  790 ---------VKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE--DSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITA 858
Cdd:COG4717    282 vlgllallfLLLAREKASLGKEAEELQALPALEELEEEELEEllAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  859 EREMVLAQEESARTNAEKQVEELLMAMEKVKQelesmkaklsstQQSLAEKETHLTNLRAERRKHLEEVlemkqEALLAA 938
Cdd:COG4717    362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQ------------AEEYQELKEELEELEEQLEELLGEL-----EELLEA 424
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1720416765  939 ISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ 978
Cdd:COG4717    425 LDEEELEEELEELEEELEELEEELEELREELAELEAELEQ 464
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
264-590 4.87e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 4.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  264 EENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSkgLSAKATEEdheRTRRLAEAEMHV 343
Cdd:pfam12128  610 EEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQS--EKDKKNKA---LAERKDSANERL 684
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  344 HHLESLLEQKEKENNMLREEMHRRFENApDSAKTKALQTVIEMKDSKISSmerglrdLEEEIQMLKSNGALSSEEREEEM 423
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREA-RTEKQAYWQVVEGALDAQLAL-------LKAAIAARRSGAKAELKALETWY 756
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  424 KQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEelKKRAAGLQSEIGQVKQELSRKD---TELLALQTKLE----TLTNQF 496
Cdd:pfam12128  757 KRDLASLGVDPDVIAKLKREIRTLERKIERIA--VRRQEVLRYFDWYQETWLQRRPrlaTQLSNIERAISelqqQLARLI 834
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  497 SDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMlnkktKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVL 576
Cdd:pfam12128  835 ADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATL-----KEDANSEQAQGSIGERLAQLEDLKLKRDYLSESV 909
                          330
                   ....*....|....
gi 1720416765  577 QKKIENLQEQLRDK 590
Cdd:pfam12128  910 KKYVEHFKNVIADH 923
PTZ00121 PTZ00121
MAEBL; Provisional
720-985 4.88e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 4.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  720 AHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVAN 799
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  800 LKHKEQVEKKKSAQMLEEARRREDSlsdssqQLQDSLRKKDDrIEELEEALREsvqitaerEMVLAQEESARTNAEKQVE 879
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKAEAARKAEEV------RKAEELRKAED-ARKAEAARKA--------EEERKAEEARKAEDAKKAE 1227
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  880 ELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANiallELSSSKKKTQ 959
Cdd:PTZ00121  1228 AVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKK 1303
                          250       260
                   ....*....|....*....|....*.
gi 1720416765  960 EEVAALKREKDRLVQQLKQQTQNRMK 985
Cdd:PTZ00121  1304 ADEAKKKAEEAKKADEAKKKAEEAKK 1329
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
703-942 5.46e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.15  E-value: 5.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  703 LEQKKEECLKMESQLKKAHEAtLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAEL 782
Cdd:PRK05771    48 LRSLLTKLSEALDKLRSYLPK-LNPLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  783 ESLTSRQVKDQNKK-------VANLKHKEQVEKKKsaqmLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALREsvq 855
Cdd:PRK05771   127 EPWGNFDLDLSLLLgfkyvsvFVGTVPEDKLEELK----LESDVENVEYISTDKGYVYVVVVVLKELSDEVEEELKK--- 199
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  856 itaeremvlAQEESARTNAEKQVEELLmamEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEmKQEAL 935
Cdd:PRK05771   200 ---------LGFERLELEEEGTPSELI---REIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELE-RAEAL 266

                   ....*...
gi 1720416765  936 L-AAISEK 942
Cdd:PRK05771   267 SkFLKTDK 274
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
543-680 6.52e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 6.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  543 KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTleEAL 622
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEY--EAL 94
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720416765  623 ADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKE 680
Cdd:COG1579     95 QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELA 152
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
331-772 6.72e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 6.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  331 ERTRRLAEAEMHVHHLESLLEQKEKENNMLREE---MHRRFENAPDSAKTKALQTVIEMKDSKISSMERG---LRDLEEE 404
Cdd:COG4717     85 EKEEEYAELQEELEELEEELEELEAELEELREElekLEKLLQLLPLYQELEALEAELAELPERLEELEERleeLRELEEE 164
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  405 IQMLKSNGALSSEEREEEMKQMEVYrshskfMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLA 484
Cdd:COG4717    165 LEELEAELAELQEELEELLEQLSLA------TEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEA 238
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  485 LQ-----TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEI 559
Cdd:COG4717    239 AAleerlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEE 318
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  560 HDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQadttntdtalttleeaLADKERTIERLKEQRDRD 639
Cdd:COG4717    319 EELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ----------------LEELEQEIAALLAEAGVE 382
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  640 EREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASslASSGLKKDSRLKTLEIALEQKKEECLKMESQLKK 719
Cdd:COG4717    383 DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD--EEELEEELEELEEELEELEEELEELREELAELEA 460
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720416765  720 AHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEK 772
Cdd:COG4717    461 ELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
PRK01156 PRK01156
chromosome segregation protein; Provisional
431-906 7.58e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.74  E-value: 7.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  431 SHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESl 510
Cdd:PRK01156   183 SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTA- 261
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  511 takEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML---DVKERKVNVLQKKIENLQ--- 584
Cdd:PRK01156   262 ---ESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILsniDAEINKYHAIIKKLSVLQkdy 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  585 EQLRDKEKQMSSLKERVKSLQadttntdtaltTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLL 664
Cdd:PRK01156   339 NDYIKKKSRYDDLNNQILELE-----------GYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI 407
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  665 QGDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLE--IALEQKKEECLKMESQLKKAHEATLEARASPEMS---DRIQQ 739
Cdd:PRK01156   408 KKELNEINVKLQDISSKVSSLNQRIRALRENLDELSrnMEMLNGQSVCPVCGTTLGEEKSNHIINHYNEKKSrleEKIRE 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  740 LEREISRYKDESSKAQTEVDRLL-EILKEVENEKNDKDKKIAELESLtsrQVKDQNKKVANLKHKEQVEKKKSAQMLEEA 818
Cdd:PRK01156   488 IEIEVKDIDEKIVDLKKRKEYLEsEEINKSINEYNKIESARADLEDI---KIKINELKDKHDKYEEIKNRYKSLKLEDLD 564
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  819 RRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAK 898
Cdd:PRK01156   565 SKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKIL 644

                   ....*...
gi 1720416765  899 LSSTQQSL 906
Cdd:PRK01156   645 IEKLRGKI 652
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
675-1010 8.08e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.57  E-value: 8.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  675 LLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLK-----KAHEATLEARAS--PEMSDRIQQLEREISRY 747
Cdd:pfam17380  274 LLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKleeaeKARQAEMDRQAAiyAEQERMAMERERELERI 353
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  748 KDESSKAQTEVDRLLEILKEVEnekndkdkKIAELESLtsrQVKDQNKkvaNLKHKEQVEKKKSAQMLEEARRR------ 821
Cdd:pfam17380  354 RQEERKRELERIRQEEIAMEIS--------RMRELERL---QMERQQK---NERVRQELEAARKVKILEEERQRkiqqqk 419
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  822 ---EDSLSDSSQQLQDSLRK-KDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKA 897
Cdd:pfam17380  420 vemEQIRAEQEEARQREVRRlEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEK 499
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  898 KLSSTQQSLAEKEthltnlraERRKHLEEVLEMKQEALLAAISEKDAniallelsSSKKKTQEEVaalkREKDRLVQQLK 977
Cdd:pfam17380  500 ELEERKQAMIEEE--------RKRKLLEKEMEERQKAIYEEERRREA--------EEERRKQQEM----EERRRIQEQMR 559
                          330       340       350
                   ....*....|....*....|....*....|...
gi 1720416765  978 QQTQNRMKLMADNYEDDHFRSSRSNQTNHKPSP 1010
Cdd:pfam17380  560 KATEERSRLEAMEREREMMRQIVESEKARAEYE 592
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
514-747 8.12e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 8.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  514 EQRAAILQTEVDALR------LRLEEKETMLnKKTKQIQDMAEEKGTQAGEIHDLKDMLDV--KERKVNVLQKKIENLQE 585
Cdd:COG4913    224 FEAADALVEHFDDLErahealEDAREQIELL-EPIRELAERYAAARERLAELEYLRAALRLwfAQRRLELLEAELEELRA 302
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  586 QLRDKEKQMSSLKERvkslqadttntdtalttleeaLADKERTIERLKEQRDRDereKQEEIDTYKKDLKDLREKVSLLQ 665
Cdd:COG4913    303 ELARLEAELERLEAR---------------------LDALREELDELEAQIRGN---GGDRLEQLEREIERLERELEERE 358
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  666 GDLSEKEASLLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARAspEMSDRIQQLEREIS 745
Cdd:COG4913    359 RRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELR--ELEAEIASLERRKS 436

                   ..
gi 1720416765  746 RY 747
Cdd:COG4913    437 NI 438
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
559-981 8.87e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 43.46  E-value: 8.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  559 IHDLKDMLDVKERKVNV-LQKKIENLQ-EQLRD----KEKQMSSLKERVKS-LQADTTNTDTALTTLEEALADKERTIE- 630
Cdd:NF033838    71 LSEIQKSLDKRKHTQNVaLNKKLSDIKtEYLYElnvlKEKSEAELTSKTKKeLDAAFEQFKKDTLEPGKKVAEATKKVEe 150
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  631 ---RLKEQRDRDERekQEEIDTYKKDLKDLREkvsllqGDLSEKEASLLDIKEHASslassGLKKDSRLKTLEIALEQKK 707
Cdd:NF033838   151 aekKAKDQKEEDRR--NYPTNTYKTLELEIAE------SDVEVKKAELELVKEEAK-----EPRDEEKIKQAKAKVESKK 217
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  708 EECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDES-SKAQTEVDRLLEILKEVENEKNDKDKKIAElESLT 786
Cdd:NF033838   218 AEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPkRRAKRGVLGEPATPDKKENDAKSSDSSVGE-ETLP 296
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  787 SRQVKDQnKKVANLKHKEQVEKKKSAQMLEEARRREDSLSdssqqlqdslrkkddrIEELEEALRESVQITAEREMVLAQ 866
Cdd:NF033838   297 SPSLKPE-KKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNT----------------YKTLELEIAESDVKVKEAELELVK 359
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  867 EESARTNAEKQVeellmamEKVKQELESMKA---KLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEA------LLA 937
Cdd:NF033838   360 EEAKEPRNEEKI-------KQAKAKVESKKAeatRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPApapqpeKPA 432
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1720416765  938 AISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQ 981
Cdd:NF033838   433 PKPEKPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTE 476
46 PHA02562
endonuclease subunit; Provisional
209-421 9.02e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.08  E-value: 9.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  209 TIWKEQYRVVQEENQHMQMTIQALQDELRIQRDlnqlFQQDSSSRTGEPcVAELTE------ENFQRLHAEHERQAKELF 282
Cdd:PHA02562   170 KLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNK----NIEEQRKKNGEN-IARKQNkydelvEEAKTIKAEIEELTDELL 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  283 LLRKTLEEME---LRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNM 359
Cdd:PHA02562   245 NLVMDIEDPSaalNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDE 324
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720416765  360 LREEMHRRFENapdSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREE 421
Cdd:PHA02562   325 LEEIMDEFNEQ---SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAK 383
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
535-756 9.21e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 9.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  535 ETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ------ADT 608
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReelgerARA 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  609 TNTDTALTTLEEALADKE------RTIERLKEQRDRDerekQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHA 682
Cdd:COG3883     95 LYRSGGSVSYLDVLLGSEsfsdflDRLSALSKIADAD----ADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720416765  683 SSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQT 756
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
639-852 1.08e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  639 DEREKQEEIDTYKKDLKDLREKVSLLQgDLSEKEASLLDIKEHASSLAssglKKDSRLKTLEialeqkkeeclkmesQLK 718
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALE-DAREQIELLEPIRELAERYA----AARERLAELE---------------YLR 278
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  719 KAHEATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKD--------KKIAELES---LTS 787
Cdd:COG4913    279 AALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgdrleqleREIERLEReleERE 358
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720416765  788 RQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRE 852
Cdd:COG4913    359 RRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE 423
PRK11281 PRK11281
mechanosensitive channel MscK;
369-735 1.13e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  369 ENAPDSAKTKALQTVIE-MKDSKISSMERGL--RDLEEEIQMLKSngALSSEEREEEMKQmEVYRSHSKFMKNK--VEQL 443
Cdd:PRK11281    30 ASNGDLPTEADVQAQLDaLNKQKLLEAEDKLvqQDLEQTLALLDK--IDRQKEETEQLKQ-QLAQAPAKLRQAQaeLEAL 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  444 KEELSSKDAQG------EELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE----VLKESLTAK 513
Cdd:PRK11281   107 KDDNDEETRETlstlslRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQqirnLLKGGKVGG 186
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  514 EQ----RAAILQTEVDALRLRLEEKETMLNKKTkQIQDMAEEKgtqageihdlkdmLDVKERKVNVLQKKIENLQEQLRD 589
Cdd:PRK11281   187 KAlrpsQRVLLQAEQALLNAQNDLQRKSLEGNT-QLQDLLQKQ-------------RDYLTARIQRLEHQLQLLQEAINS 252
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  590 KEKQMSslKERVKSLQAdttnTDTALTTLEEALADKERTI-----ERLKEQRDRDEREKQEEIDTyKKDL-------KDL 657
Cdd:PRK11281   253 KRLTLS--EKTVQEAQS----QDEAARIQANPLVAQELEInlqlsQRLLKATEKLNTLTQQNLRV-KNWLdrltqseRNI 325
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  658 REKVSLLQGDL-------SEKEA--SLLDIKEHASSLAssglkkDSRLKTLEIalEQKKEECLKMEsqlkkAHEATLEAR 728
Cdd:PRK11281   326 KEQISVLKGSLllsrilyQQQQAlpSADLIEGLADRIA------DLRLEQFEI--NQQRDALFQPD-----AYIDKLEAG 392

                   ....*..
gi 1720416765  729 ASPEMSD 735
Cdd:PRK11281   393 HKSEVTD 399
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
212-562 1.15e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  212 KEQYRVVQEENQHMQMTiqaLQDELRIQRDLNQLFQQdsSSRTGEPCVAELTE---------ENFQRLHAEHErqakELF 282
Cdd:pfam15921  474 KEMLRKVVEELTAKKMT---LESSERTVSDLTASLQE--KERAIEATNAEITKlrsrvdlklQELQHLKNEGD----HLR 544
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  283 LLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSA------KATEEDHERTRRLAEAEMHVHHLESLLEQKEKE 356
Cdd:pfam15921  545 NVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAgamqveKAQLEKEINDRRLELQEFKILKDKKDAKIRELE 624
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  357 NNMLREEMHRRFENAPDSAKTKALQTVIEMKD---SKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVyrsHS 433
Cdd:pfam15921  625 ARVSDLELEKVKLVNAGSERLRAVKDIKQERDqllNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKM---QL 701
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  434 KFMKNKVEQLKEELSSKDAQGEELKKRAAGLQSEIgqvkqelSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAK 513
Cdd:pfam15921  702 KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQI-------TAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKL 774
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1720416765  514 EQRAAILQTEVDALRLRLE---EKETMLNKKTKQIQDMAEEKGTQAGEIHDL 562
Cdd:pfam15921  775 SQELSTVATEKNKMAGELEvlrSQERRLKEKVANMEVALDKASLQFAECQDI 826
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
565-986 1.23e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  565 MLDVKErkvnvLQKKIENLQEQ---LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEaLADKERTIERLKEQRDRDER 641
Cdd:COG4913    217 MLEEPD-----TFEAADALVEHfddLERAHEALEDAREQIELLEPIRELAERYAAARER-LAELEYLRAALRLWFAQRRL 290
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  642 EK-QEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEhasSLASSGLKK----DSRLKTLEIALEQKKEECLKMESQ 716
Cdd:COG4913    291 ELlEAELEELRAELARLEAELERLEARLDALREELDELEA---QIRGNGGDRleqlEREIERLERELEERERRRARLEAL 367
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  717 LKKAHEATLEARAspEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSR-------- 788
Cdd:COG4913    368 LAALGLPLPASAE--EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNiparllal 445
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  789 ----------------------QVKDQN-------------------------KKVA------NLKHKEQVEKKKSAQML 815
Cdd:COG4913    446 rdalaealgldeaelpfvgeliEVRPEEerwrgaiervlggfaltllvppehyAAALrwvnrlHLRGRLVYERVRTGLPD 525
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  816 EEARR-REDSL--------SDSSQQLQDSLRKKDDRI--EELEEALRESVQITAEREMvlAQEESART------------ 872
Cdd:COG4913    526 PERPRlDPDSLagkldfkpHPFRAWLEAELGRRFDYVcvDSPEELRRHPRAITRAGQV--KGNGTRHEkddrrrirsryv 603
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  873 ---NAEKQVEELlmamekvKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKH--LEEVLEMKQ--EALLAAISEKDAN 945
Cdd:COG4913    604 lgfDNRAKLAAL-------EAELAELEEELAEAEERLEALEAELDALQERREALqrLAEYSWDEIdvASAEREIAELEAE 676
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1720416765  946 IALLELSSSK-KKTQEEVAALKREKDRLVQQLKQQTQNRMKL 986
Cdd:COG4913    677 LERLDASSDDlAALEEQLEELEAELEELEEELDELKGEIGRL 718
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
354-898 1.59e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.73  E-value: 1.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  354 EKENNMLREEMHRRFENApDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHS 433
Cdd:TIGR01612  710 DKIQNMETATVELHLSNI-ENKKNELLDIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKI 788
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  434 KFMKNK------VEQLKEELSSKD-AQGEELKKRAAGLQSEIGQVKQELSRKDTELLalqTKLETLTNQFSDSKQHIEVL 506
Cdd:TIGR01612  789 SEIKNHyndqinIDNIKDEDAKQNyDKSKEYIKTISIKEDEIFKIINEMKFMKDDFL---NKVDKFINFENNCKEKIDSE 865
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  507 KESLT--AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDmaeekgtQAGEIHDLKdmldvkerKVNVLQKKIENLQ 584
Cdd:TIGR01612  866 HEQFAelTNKIKAEISDDKLNDYEKKFNDSKSLINEINKSIEE-------EYQNINTLK--------KVDEYIKICENTK 930
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  585 EQLRDKEKQMSSLKER----VKSLQADTTNTDTALTTLEEALADKERTIERL-KEQRDRDEREKQEEIDTYKKDLKDL-- 657
Cdd:TIGR01612  931 ESIEKFHNKQNILKEIlnknIDTIKESNLIEKSYKDKFDNTLIDKINELDKAfKDASLNDYEAKNNELIKYFNDLKANlg 1010
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  658 REKVSLLQGDLSEKEASLLDIKEHASSLAS--SGLKKDSRLKTLEIALEQKKEECLKMESQLKKA-HEATLEARASPEMS 734
Cdd:TIGR01612 1011 KNKENMLYHQFDEKEKATNDIEQKIEDANKniPNIEIAIHTSIYNIIDEIEKEIGKNIELLNKEIlEEAEINITNFNEIK 1090
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  735 DRIQ-------------QLEREISRYKDESSKAQTEVDR----LLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKV 797
Cdd:TIGR01612 1091 EKLKhynfddfgkeeniKYADEINKIKDDIKNLDQKIDHhikaLEEIKKKSENYIDEIKAQINDLEDVADKAISNDDPEE 1170
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  798 ANLKHKEQVEKkksaqmleearrredslSDSSQQLQDSLRKKDDRIEELEE---ALRESVQITAEREMVLAQEESARTNA 874
Cdd:TIGR01612 1171 IEKKIENIVTK-----------------IDKKKNIYDEIKKLLNEIAEIEKdktSLEEVKGINLSYGKNLGKLFLEKIDE 1233
                          570       580
                   ....*....|....*....|....*
gi 1720416765  875 E-KQVEELLMAMEKVKQELESMKAK 898
Cdd:TIGR01612 1234 EkKKSEHMIKAMEAYIEDLDEIKEK 1258
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
272-709 1.69e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  272 AEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGL---SAKATEEDHERTRRLAEAEMHVHHLES 348
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqeLEALEAELAELPERLEELEERLEELRE 160
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  349 LLEQKEKENNMLREEMHRRFEnapdsaktkALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEV 428
Cdd:COG4717    161 LEEELEELEAELAELQEELEE---------LLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  429 YRShSKFMKNKVEQLKEELSSKDAQGeelkkRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE 508
Cdd:COG4717    232 LEN-ELEAAALEERLKEARLLLLIAA-----ALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAE 305
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  509 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKdmldvKERKVNVLQKKIENLQEQLR 588
Cdd:COG4717    306 ELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE-----EELQLEELEQEIAALLAEAG 380
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  589 -DKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDE-REKQEEIDTYKKDLKDLREKVSLLQG 666
Cdd:COG4717    381 vEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEElEELEEELEELEEELEELREELAELEA 460
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1720416765  667 DLSEKEAS-----LLDIKEHASSLASSGLKKDSRLKTLEIALEQKKEE 709
Cdd:COG4717    461 ELEQLEEDgelaeLLQELEELKAELRELAEEWAALKLALELLEEAREE 508
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
280-831 2.18e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  280 ELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML--QSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKEN 357
Cdd:pfam12128  259 RLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLddQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAD 338
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  358 NMLR--------------EEMHRRFENAPDSAK--TKALQTVIEMKDS----KISSMERGLRDLEEEIQMLKSNG----- 412
Cdd:pfam12128  339 IETAaadqeqlpswqselENLEERLKALTGKHQdvTAKYNRRRSKIKEqnnrDIAGIKDKLAKIREARDRQLAVAeddlq 418
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  413 ALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGlQSEIGQVKQELSRKDTELLALQTKLETL 492
Cdd:pfam12128  419 ALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENF-DERIERAREEQEAANAEVERLQSELRQA 497
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  493 TNQFSDSKQHievlkesLTAKEQRAAILQTEVDALRLRLEEKE-TMLNKKTKQIQDMAEEKGT----------------- 554
Cdd:pfam12128  498 RKRRDQASEA-------LRQASRRLEERQSALDELELQLFPQAgTLLHFLRKEAPDWEQSIGKvispellhrtdldpevw 570
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  555 -----------------QAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT 617
Cdd:pfam12128  571 dgsvggelnlygvkldlKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN 650
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  618 LEEAL----ADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDL----------------------REKVSLLQGDLSEK 671
Cdd:pfam12128  651 ARLDLrrlfDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLdkkhqawleeqkeqkreartekQAYWQVVEGALDAQ 730
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  672 EASLLDI----------------KEHASSLASSGL--KKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARAS--P 731
Cdd:pfam12128  731 LALLKAAiaarrsgakaelkaleTWYKRDLASLGVdpDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQrrP 810
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  732 EMSDRIQQLEREISRYKDESSKAQTEVDRLleiLKEVENEKNDKDKKIAELESLTsRQVKDQNKKVANLKHKEQVEKKKS 811
Cdd:pfam12128  811 RLATQLSNIERAISELQQQLARLIADTKLR---RAKLEMERKASEKQQVRLSENL-RGLRCEMSKLATLKEDANSEQAQG 886
                          650       660
                   ....*....|....*....|....*
gi 1720416765  812 A-----QMLEEARRREDSLSDSSQQ 831
Cdd:pfam12128  887 SigerlAQLEDLKLKRDYLSESVKK 911
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
822-992 2.34e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  822 EDSLSDSSQQLQDSLRKKDDRIEELEEALREsvqitAEREMVLAQEESARTNAEKQVEELLmamekvkQELESMKAKLSS 901
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEE-----AEAALEEFRQKNGLVDLSEEAKLLL-------QQLSELESQLAE 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  902 TQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK--DANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQ 979
Cdd:COG3206    231 ARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQlaELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310
                          170
                   ....*....|...
gi 1720416765  980 TQNRMKLMADNYE 992
Cdd:COG3206    311 AQRILASLEAELE 323
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
375-606 2.82e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 2.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  375 AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKS-NGALS-SEEREEEMKQMEVYRShskfmknKVEQLKEELSSKDA 452
Cdd:COG3206    168 LRREEARKALEFLEEQLPELRKELEEAEAALEEFRQkNGLVDlSEEAKLLLQQLSELES-------QLAEARAELAEAEA 240
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  453 QGEELKKRAAGLQSEIGQVKQ--ELSRKDTELLALQTKLETLTNQFSDS-------KQHIEVLKESLTAKEQRAAI-LQT 522
Cdd:COG3206    241 RLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPNhpdvialRAQIAALRAQLQQEAQRILAsLEA 320
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  523 EVDALRLRLEEKETMLNKKTKQIQDMAEekgtqageihdlkdmldvkerkvnvLQKKIENLQEQLRDKEKQMSSLKERVK 602
Cdd:COG3206    321 ELEALQAREASLQAQLAQLEARLAELPE-------------------------LEAELRRLEREVEVARELYESLLQRLE 375

                   ....
gi 1720416765  603 SLQA 606
Cdd:COG3206    376 EARL 379
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
736-884 2.87e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  736 RIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLtSRQVKDqNKKVANLKHKEQVEKKKSAQML 815
Cdd:COG1579     32 ELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ-LGNVRN-NKEYEALQKEIESLKRRISDLE 109
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720416765  816 EEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMA 884
Cdd:COG1579    110 DEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPELLA 178
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
418-745 3.11e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 41.76  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  418 EREEEMKQMEVYRSHSKFMKNKVEQLKEELSskDAQGEELKKRAAGLQSEIGQVKQELSRKDTEL---LALQTKLETLTN 494
Cdd:PLN03229   416 ERKVNMKKREAVKTPVRELEGEVEKLKEQIL--KAKESSSKPSELALNEMIEKLKKEIDLEYTEAviaMGLQERLENLRE 493
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  495 QFSDSKQHIEVLKESLTAKEQRAAilqtevDALRLRLEEKETMLNKKTKqiQDMAEekgtqagEIHDLKDMLDVKERKVN 574
Cdd:PLN03229   494 EFSKANSQDQLMHPVLMEKIEKLK------DEFNKRLSRAPNYLSLKYK--LDMLN-------EFSRAKALSEKKSKAEK 558
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  575 V---LQKKIENLQEQLRDKEKqMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRD---EREKQEEID 648
Cdd:PLN03229   559 LkaeINKKFKEVMDRPEIKEK-MEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELELAGVLKSMGlevIGVTKKNKD 637
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  649 TYKKDL-KDLREKVSLLQGDLSEKEASLLDikehasslaSSGLKKDSRLKTLEIALEQK------KEECLKMESQLKkah 721
Cdd:PLN03229   638 TAEQTPpPNLQEKIESLNEEINKKIERVIR---------SSDLKSKIELLKLEVAKASKtpdvteKEKIEALEQQIK--- 705
                          330       340
                   ....*....|....*....|....
gi 1720416765  722 EATLEARASPEMSDRIQQLEREIS 745
Cdd:PLN03229   706 QKIAEALNSSELKEKFEELEAELA 729
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
736-900 3.26e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 3.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  736 RIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELESLTSR---QVKDQNKKVAnlKHKEQVEKKKSA 812
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRlelEIEEVEARIK--KYEEQLGNVRNN 88
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  813 QMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALREsvqITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQEL 892
Cdd:COG1579     89 KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAE---LEAELAELEAELEEKKAELDEELAELEAELEELEAER 165

                   ....*...
gi 1720416765  893 ESMKAKLS 900
Cdd:COG1579    166 EELAAKIP 173
COG5022 COG5022
Myosin heavy chain [General function prediction only];
742-1010 3.42e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.60  E-value: 3.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  742 REISRYKDESSKAQTEVDRLLEILKEVENE-KNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARR 820
Cdd:COG5022    761 RRRYLQALKRIKKIQVIQHGFRLRRLVDYElKWRLFIKLQPLLSLLGSRKEYRSYLACIIKLQKTIKREKKLRETEEVEF 840
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  821 REDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQIT--AEREMVLAQEESARTNAEKQVEELL--MAMEKVKQELESMK 896
Cdd:COG5022    841 SLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVelAERQLQELKIDVKSISSLKLVNLELesEIIELKKSLSSDLI 920
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  897 AKLSSTQQSLAEKETHLTNLRaerrkhLEEVLEMKQEallaaisEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQL 976
Cdd:COG5022    921 ENLEFKTELIARLKKLLNNID------LEEGPSIEYV-------KLPELNKLHEVESKLKETSEEYEDLLKKSTILVREG 987
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1720416765  977 KQQTQNRMKLMA------DNYEDDHFRSSRSNQTNHKPSP 1010
Cdd:COG5022    988 NKANSELKNFKKelaelsKQYGALQESTKQLKELPVEVAE 1027
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
697-852 3.83e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 3.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  697 KTLEIALEQKKEECLKMESQlKKAHEATLEARASPEMSDRIQQLEREISRYkdesskaQTEVDRLLEILKEvenekndKD 776
Cdd:COG2433    376 LSIEEALEELIEKELPEEEP-EAEREKEHEERELTEEEEEIRRLEEQVERL-------EAEVEELEAELEE-------KD 440
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720416765  777 KKIAELEsltsrqvkdqnkkvanlkhkEQVEKKKSAQMLEEARRREDSLSDSS-QQLQDSLRKKDDRIEELEEALRE 852
Cdd:COG2433    441 ERIERLE--------------------RELSEARSEERREIRKDREISRLDREiERLERELEEERERIEELKRKLER 497
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
384-606 4.13e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 41.09  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  384 IEMKDSKIS-----------SMERGLRDLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDA 452
Cdd:pfam07902   92 LELTDTKNSnlwskiklnnnGMLREYHNDTIKTEIVESAEGIATRISEDTDKKLALINETISGIRREYQDADRQLSSSYQ 171
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  453 QGEE-----LKKRAAGLQSEIGQVKQELSRK-DTELLALQTKLETLTNQFSDS-KQHIEVLKESLTAKEQraailqtevd 525
Cdd:pfam07902  172 AGIEglkatMASDKIGLQAEIQASAQGLSQRyDNEIRKLSAKITTTSSGTTEAyESKLDDLRAEFTRSNQ---------- 241
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  526 ALRLRLEEKETMLnkktkqiqdmaeeKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 605
Cdd:pfam07902  242 GMRTELESKISGL-------------QSTQQSTAYQISQEISNREGAVSRVQQDLDSYQRRLQDAEKNYSSLTQTVKGLQ 308

                   .
gi 1720416765  606 A 606
Cdd:pfam07902  309 S 309
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
260-896 4.24e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 41.28  E-value: 4.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  260 AELTEENFQRLhaehERQAKELFLLRKTLEEMELRIETQKQTLNARdesikkllemlqskGLSAKATEEDHERTRR-LAE 338
Cdd:pfam07111   65 AELISRQLQEL----RRLEEEVRLLRETSLQQKMRLEAQAMELDAL--------------AVAEKAGQAEAEGLRAaLAG 126
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  339 AEMHVHHLESLLEQKEKENNMLREEMHrrfenapdSAKTKALQTVIEMKDSKISSMERGLRDLEEEiqmlksngalssee 418
Cdd:pfam07111  127 AEMVRKNLEEGSQRELEEIQRLHQEQL--------SSLTQAHEEALSSLTSKAEGLEKSLNSLETK-------------- 184
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  419 REEEMKQMEVYRSHSKFMKNKVEQLKEELSSKDAQGEELKKRAAGlqseigQVKQELSRKDTELlALQTKLETLtnqfsd 498
Cdd:pfam07111  185 RAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLRKYVGE------QVPPEVHSQTWEL-ERQELLDTM------ 251
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  499 skQHIEVLKESLTAKEQraaILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAgeihdlKDMLDVKERKVNVLQK 578
Cdd:pfam07111  252 --QHLQEDRADLQATVE---LLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFPKKC------RSLLNRWREKVFALMV 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  579 KIENLQEQLRDKEKQmssLKERVKSLQADTTNTDTALTTLEEALADK--ERTIERLK--------EQRDRDEREKQEEID 648
Cdd:pfam07111  321 QLKAQDLEHRDSVKQ---LRGQVAELQEQVTSQSQEQAILQRALQDKaaEVEVERMSakglqmelSRAQEARRRQQQQTA 397
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  649 TYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLA---SSGLKKDSRLKTL---EIALEQkkeecLKMESQLKKAHE 722
Cdd:pfam07111  398 SAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARIPSLSnrlSYAVRKVHTIKGLmarKVALAQ-----LRQESCPPPPPA 472
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  723 ATLEARASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEilkEVENEKNDKDKKIAELEsltsRQVKDQNKKVANLKH 802
Cdd:pfam07111  473 PPVDADLSLELEQLREERNRLDAELQLSAHLIQQEVGRARE---QGEAERQQLSEVAQQLE----QELQRAQESLASVGQ 545
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  803 KEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKddrIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELL 882
Cdd:pfam07111  546 QLEVARQGQQESTEEAASLRQELTQQQEIYGQALQEK---VAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRA 622
                          650
                   ....*....|....
gi 1720416765  883 MAMEKVKQELESMK 896
Cdd:pfam07111  623 TQEKERNQELRRLQ 636
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
306-520 5.60e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 40.68  E-value: 5.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  306 DESIKKLLEMLQSKGLS---AKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEM----HRRFENAPDSAKTK 378
Cdd:PRK05771    15 KSYKDEVLEALHELGVVhieDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKkkvsVKSLEELIKDVEEE 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  379 ALQTVIEMKD--SKISSMERGLRDLEEEIQMLKSNGALSSE---EREEEMKQMEVYRSHskfmKNKVEQLKEELSS---- 449
Cdd:PRK05771    95 LEKIEKEIKEleEEISELENEIKELEQEIERLEPWGNFDLDlslLLGFKYVSVFVGTVP----EDKLEELKLESDVenve 170
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  450 -------------------KDAQGEELKKraAGLQ----SEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQH---- 502
Cdd:PRK05771   171 yistdkgyvyvvvvvlkelSDEVEEELKK--LGFErlelEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKylee 248
                          250
                   ....*....|....*...
gi 1720416765  503 IEVLKESLTAKEQRAAIL 520
Cdd:PRK05771   249 LLALYEYLEIELERAEAL 266
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
825-988 5.97e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 5.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  825 LSDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQ 904
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  905 SLAEKETHLTNLRAERRKHLEEVLEMKQ----EALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQT 980
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                   ....*...
gi 1720416765  981 QNRMKLMA 988
Cdd:COG4942    171 AERAELEA 178
GAS pfam13851
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ...
442-632 6.06e-03

Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.


Pssm-ID: 464001 [Multi-domain]  Cd Length: 200  Bit Score: 39.12  E-value: 6.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  442 QLKEELsskdaqgEELKKRAAGLQSEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHievlKESLTAKEQRAAILQ 521
Cdd:pfam13851   30 SLKEEI-------AELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLENYEKD----KQSLKNLKARLKVLE 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  522 TEVDALRLRLEEKEtMLNKKTKQIQDMAEEKGTQAgeIHDLKDMLDVKErkvNVLQKKIENLQEQLRDKEKQMSSLKERV 601
Cdd:pfam13851   99 KELKDLKWEHEVLE-QRFEKVERERDELYDKFEAA--IQDVQQKTGLKN---LLLEKKLQALGETLEKKEAQLNEVLAAA 172
                          170       180       190
                   ....*....|....*....|....*....|.
gi 1720416765  602 KslqADTTNTDTALTTLEEALADKERTIERL 632
Cdd:pfam13851  173 N---LDPDALQAVTEKLEDVLESKNQLIKDL 200
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
328-566 6.47e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 6.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  328 EDHERTRRLAE-AEMHVHHLESLLEQKEKENNMLREEMHRRFENAPdsAKTKALQTVIEMKDSKISSMERGLRDLEEEIQ 406
Cdd:COG4913    235 DDLERAHEALEdAREQIELLEPIRELAERYAAARERLAELEYLRAA--LRLWFAQRRLELLEAELEELRAELARLEAELE 312
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  407 MLksngalssEEREEEMKQmevyrshskfmknKVEQLKEELSSKDAQgeelkkRAAGLQSEIGQVKQELSRKDTELLALQ 486
Cdd:COG4913    313 RL--------EARLDALRE-------------ELDELEAQIRGNGGD------RLEQLEREIERLERELEERERRRARLE 365
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  487 TKLETLTNQFSDSKQ----HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDL 562
Cdd:COG4913    366 ALLAALGLPLPASAEefaaLRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLAL 445

                   ....
gi 1720416765  563 KDML 566
Cdd:COG4913    446 RDAL 449
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
503-668 6.61e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 40.61  E-value: 6.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  503 IEVLKESLTAKEQRAAILQTEVDALRLRLEEKEtmLNKKTKQIQDMAEEKGtqageihDLKDMLDVKERKVNVLQKKIEN 582
Cdd:COG2433    382 LEELIEKELPEEEPEAEREKEHEERELTEEEEE--IRRLEEQVERLEAEVE-------ELEAELEEKDERIERLERELSE 452
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  583 LQEQLRD---KEKQMSSLKERVKSLQadttntdTALTTLEEALADKERTIERLKEQRDRDEREKQE---EIDTYKKD-LK 655
Cdd:COG2433    453 ARSEERReirKDREISRLDREIERLE-------RELEEERERIEELKRKLERLKELWKLEHSGELVpvkVVEKFTKEaIR 525
                          170
                   ....*....|...
gi 1720416765  656 DLREKVSLLQGDL 668
Cdd:COG2433    526 RLEEEYGLKEGDV 538
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
703-989 7.13e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 40.26  E-value: 7.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  703 LEQKKEECLKMESQLKKAHEATLEAR---------ASPEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVEN--- 770
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQRekekerykrDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAsse 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  771 -----------EKNDKDKKIAELE----SLTSR---------QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDSLS 826
Cdd:pfam07888  112 elseekdallaQRAAHEARIRELEedikTLTQRvlereteleRMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  827 DSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQeesartnaekqveellmaMEKVKQELESMKAKLSSTQQSL 906
Cdd:pfam07888  192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE------------------NEALLEELRSLQERLNASERKV 253
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  907 AEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLE-----------LSSSKKKTQEEVAALKREKDRLVQQ 975
Cdd:pfam07888  254 EGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREgrarwaqeretLQQSAEADKDRIEKLSAELQRLEER 333
                          330
                   ....*....|....
gi 1720416765  976 LKQQTQNRMKLMAD 989
Cdd:pfam07888  334 LQEERMEREKLEVE 347
PRK12704 PRK12704
phosphodiesterase; Provisional
532-641 7.24e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.15  E-value: 7.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  532 EEKETMLNKKTKQIQDMAEEKGTQAG-EIHDLKDMLdvkERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 610
Cdd:PRK12704    38 EEAKRILEEAKKEAEAIKKEALLEAKeEIHKLRNEF---EKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEK 114
                           90       100       110
                   ....*....|....*....|....*....|..
gi 1720416765  611 TDTALTTLEEALADKERTIERL-KEQRDRDER 641
Cdd:PRK12704   115 KEKELEQKQQELEKKEEELEELiEEQLQELER 146
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
520-811 7.89e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 39.51  E-value: 7.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  520 LQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKE 599
Cdd:COG1340     13 LEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNELRE 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  600 RVKSLQADTTNtdtalttleeaLADKERTIERLKEQRDRDEREKQEEIDTYKKDlKDLREKVSLLqgdlsekeASLLDIK 679
Cdd:COG1340     93 ELDELRKELAE-----------LNKAGGSIDKLRKEIERLEWRQQTEVLSPEEE-KELVEKIKEL--------EKELEKA 152
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  680 EHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEATLEARaspemsDRIQQLEREISRYKDESSKAQTEVD 759
Cdd:COG1340    153 KKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELY------KEADELRKEADELHKEIVEAQEKAD 226
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1720416765  760 RLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKS 811
Cdd:COG1340    227 ELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEELEEKAEEIFEKLKK 278
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
502-770 7.94e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 40.30  E-value: 7.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  502 HIEVLKESLTAKEQRAAI-LQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAgeIHDLKDMLDVKERKVNVLQKKI 580
Cdd:PRK05771    32 HIEDLKEELSNERLRKLRsLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEEL--IKDVEEELEKIEKEIKELEEEI 109
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  581 ENLQEQLRDKEKQMSSLkERVKSLqadttntdtalTTLEEALADKERTIERLKE-QRDRDEREKQEEIDTYKKDLKDLRE 659
Cdd:PRK05771   110 SELENEIKELEQEIERL-EPWGNF-----------DLDLSLLLGFKYVSVFVGTvPEDKLEELKLESDVENVEYISTDKG 177
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  660 KVSLLQGDLSEKEASLLDIkehassLASSGLKKD--SRLKTLEIALEQKKEEclkmESQLKKaheatlearaspemsdRI 737
Cdd:PRK05771   178 YVYVVVVVLKELSDEVEEE------LKKLGFERLelEEEGTPSELIREIKEE----LEEIEK----------------ER 231
                          250       260       270
                   ....*....|....*....|....*....|...
gi 1720416765  738 QQLEREISRYKDESSKAQTEVDRLLEILKEVEN 770
Cdd:PRK05771   232 ESLLEELKELAKKYLEELLALYEYLEIELERAE 264
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
564-784 8.76e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 39.81  E-value: 8.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  564 DMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKERTIERLKEQRDRDEREK 643
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720416765  644 QEEIDTYK--------KDLKDLREKVSLLQgDLSEKEASLLDikehasslassglkkdsRLKTLEIALEQKKEECLKMES 715
Cdd:COG3883     96 YRSGGSVSyldvllgsESFSDFLDRLSALS-KIADADADLLE-----------------ELKADKAELEAKKAELEAKLA 157
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720416765  716 QLKKAHEatlearaspEMSDRIQQLEREISRYKDESSKAQTEVDRLLEILKEVENEKNDKDKKIAELES 784
Cdd:COG3883    158 ELEALKA---------ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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