NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1720412771|ref|XP_030110168|]
View 

scavenger receptor class B member 1 isoform X3 [Mus musculus]

Protein Classification

CD36 family protein( domain architecture ID 10471559)

CD36 family protein belongs to a class of scavenger receptors that may play roles in various signal transduction mechanisms; CD36 is a multifunctional membrane protein that acts as the cellular receptor for thrombospondin-1 (TSP-1) and is required for the anti-angiogenic activity of TSP-1, and generally promotes thrombosis in conditions of oxidative stress

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CD36 pfam01130
CD36 family; The CD36 family is thought to be a novel class of scavenger receptors. There is ...
 1-393 0e+00

CD36 family; The CD36 family is thought to be a novel class of scavenger receptors. There is also evidence suggesting a possible role in signal transduction. CD36 is involved in cell adhesion.


:

Pssm-ID: 460076  Cd Length: 454  Bit Score: 533.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771   1 MWKEIPVPFYLSVYFFEVVNPNEVLN-GQKPVVRERGPYVYREFRQKVNITFND-NDTVSFVENRSLHFQPDKSHGSESD 78
Cdd:pfam01130  41 LWKKPPVPVYLKFYLFNVTNPEEFLGgGAKPKVEEVGPYVYREYREKVNVTFNDdNGTVSYQQRRTYIFDPELSVGSEDD 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771  79 YIVLPNILVLGGSILMESKPvSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLFVGMN 158
Cdd:pfam01130 121 TITTPNIPLLGAASKARNSS-FLLRLLNLLLNSLGEKLFVTRTVGELLFGYEDPLLDLAKKLLPSLPIPFDKFGLFYGRN 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 159 NSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEqCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRV 238
Cdd:pfam01130 200 GTDDGVFTVYTGKDDISKLGRIDSWNGKTHLDWWEGE-CNMINGTDGTLFPPFLTKDDTLYIFSPDLCRSLPLVYEKDVT 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 239 FEGIPTYRFTAPDTLFANGSVYPPNEGFCP-----CRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKE 313
Cdd:pfam01130 279 VKGIPGYRYVLPPNVFDNGTVNPDNKCFCPnkgneCLPSGLLDVSPCKYGAPIFLSLPHFYLADPSYLEAVEGLNPNKEK 358

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 314 HSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQVLHYAQYV 393
Cdd:pfam01130 359 HETYLDIEPTTGIPLEAAKRLQINLLVEPVPGISLLKNLPNVILPLFWFEESAELDDELANLLKKLLLVLPNIGLYLQYG 438
 
Name Accession Description Interval E-value
CD36 pfam01130
CD36 family; The CD36 family is thought to be a novel class of scavenger receptors. There is ...
 1-393 0e+00

CD36 family; The CD36 family is thought to be a novel class of scavenger receptors. There is also evidence suggesting a possible role in signal transduction. CD36 is involved in cell adhesion.


Pssm-ID: 460076  Cd Length: 454  Bit Score: 533.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771   1 MWKEIPVPFYLSVYFFEVVNPNEVLN-GQKPVVRERGPYVYREFRQKVNITFND-NDTVSFVENRSLHFQPDKSHGSESD 78
Cdd:pfam01130  41 LWKKPPVPVYLKFYLFNVTNPEEFLGgGAKPKVEEVGPYVYREYREKVNVTFNDdNGTVSYQQRRTYIFDPELSVGSEDD 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771  79 YIVLPNILVLGGSILMESKPvSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLFVGMN 158
Cdd:pfam01130 121 TITTPNIPLLGAASKARNSS-FLLRLLNLLLNSLGEKLFVTRTVGELLFGYEDPLLDLAKKLLPSLPIPFDKFGLFYGRN 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 159 NSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEqCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRV 238
Cdd:pfam01130 200 GTDDGVFTVYTGKDDISKLGRIDSWNGKTHLDWWEGE-CNMINGTDGTLFPPFLTKDDTLYIFSPDLCRSLPLVYEKDVT 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 239 FEGIPTYRFTAPDTLFANGSVYPPNEGFCP-----CRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKE 313
Cdd:pfam01130 279 VKGIPGYRYVLPPNVFDNGTVNPDNKCFCPnkgneCLPSGLLDVSPCKYGAPIFLSLPHFYLADPSYLEAVEGLNPNKEK 358

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 314 HSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQVLHYAQYV 393
Cdd:pfam01130 359 HETYLDIEPTTGIPLEAAKRLQINLLVEPVPGISLLKNLPNVILPLFWFEESAELDDELANLLKKLLLVLPNIGLYLQYG 438
 
Name Accession Description Interval E-value
CD36 pfam01130
CD36 family; The CD36 family is thought to be a novel class of scavenger receptors. There is ...
 1-393 0e+00

CD36 family; The CD36 family is thought to be a novel class of scavenger receptors. There is also evidence suggesting a possible role in signal transduction. CD36 is involved in cell adhesion.


Pssm-ID: 460076  Cd Length: 454  Bit Score: 533.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771   1 MWKEIPVPFYLSVYFFEVVNPNEVLN-GQKPVVRERGPYVYREFRQKVNITFND-NDTVSFVENRSLHFQPDKSHGSESD 78
Cdd:pfam01130  41 LWKKPPVPVYLKFYLFNVTNPEEFLGgGAKPKVEEVGPYVYREYREKVNVTFNDdNGTVSYQQRRTYIFDPELSVGSEDD 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771  79 YIVLPNILVLGGSILMESKPvSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLFVGMN 158
Cdd:pfam01130 121 TITTPNIPLLGAASKARNSS-FLLRLLNLLLNSLGEKLFVTRTVGELLFGYEDPLLDLAKKLLPSLPIPFDKFGLFYGRN 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 159 NSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEqCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRV 238
Cdd:pfam01130 200 GTDDGVFTVYTGKDDISKLGRIDSWNGKTHLDWWEGE-CNMINGTDGTLFPPFLTKDDTLYIFSPDLCRSLPLVYEKDVT 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 239 FEGIPTYRFTAPDTLFANGSVYPPNEGFCP-----CRESGIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKE 313
Cdd:pfam01130 279 VKGIPGYRYVLPPNVFDNGTVNPDNKCFCPnkgneCLPSGLLDVSPCKYGAPIFLSLPHFYLADPSYLEAVEGLNPNKEK 358

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412771 314 HSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLSTFYTQLVLMPQVLHYAQYV 393
Cdd:pfam01130 359 HETYLDIEPTTGIPLEAAKRLQINLLVEPVPGISLLKNLPNVILPLFWFEESAELDDELANLLKKLLLVLPNIGLYLQYG 438
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH