|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
749-977 |
2.06e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
:
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.53 E-value: 2.06e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 749 FRKVRSILNKLTPQMFNQLMKQVSALTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLkvpmadkpgNTVNFR 828
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNLR---------NPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 829 KLLLNRCQKEFEKdkadddvfekkqkeleaasapeertrlHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCV 908
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720408520 909 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERK---TSSRIRFMLQDVIDLRLCN 977
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVLSKDdpkLSSRLRFMLQDLIELRKNK 203
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1417-1549 |
1.90e-48 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
:
Pssm-ID: 211397 Cd Length: 134 Bit Score: 169.00 E-value: 1.90e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1417 EELSQRLEKLIMEEKADDErIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADcSTFRVDTAVIKQRVPILLKYLDSD 1496
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDE-LYKWIKENVSPELYASPGFVRALMTAVLKYAIEEK-SLPEKEKALLEKYAPLLQKYLDDD 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1720408520 1497 TEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPA 1549
Cdd:cd11559 82 EQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1215-1327 |
9.24e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
:
Pssm-ID: 397128 Cd Length: 113 Bit Score: 128.93 E-value: 9.24e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1215 VERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFVKVGVEFTLERSQITRDHMGHLLYQLVQSEKLSKQDFFKGFSE 1294
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1720408520 1295 TLELADDMAIDIPHIWLYLAELVTPMLKGGGIS 1327
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| PRK07003 super family |
cl35530 |
DNA polymerase III subunit gamma/tau; |
161-324 |
4.66e-06 |
|
DNA polymerase III subunit gamma/tau;
The actual alignment was detected with superfamily member PRK07003:
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 51.39 E-value: 4.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 161 GGGSRNPTPPIGRPASTPTPPQLP--SQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVL 238
Cdd:PRK07003 368 PGGGVPARVAGAVPAPGARAAAAVgaSAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDA 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 239 SGEKKEQAGQMPETAAGEPTPEPPRTSSPTS-----LPPLARSSlPSPMSAALSSQPLFTAEDKCELPSSKEEDAPPVP- 312
Cdd:PRK07003 448 PVPAKANARASADSRCDERDAQPPADSGSASapasdAPPDAAFE-PAPRAAAPSAATPAAVPDARAPAAASREDAPAAAa 526
|
170
....*....|..
gi 1720408520 313 SPTSCTAASGPS 324
Cdd:PRK07003 527 PPAPEARPPTPA 538
|
|
| W2 super family |
cl17013 |
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of ... |
1528-1574 |
1.15e-04 |
|
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of several translation initiation factors, including the epsilon chain of eIF2b, where it has been found to catalyze the conversion of eIF2.GDP to its active eIF2.GTP form. The structure of the domain resembles that of a set of concatenated HEAT repeats.
The actual alignment was detected with superfamily member cd11560:
Pssm-ID: 473053 [Multi-domain] Cd Length: 194 Bit Score: 44.90 E-value: 1.15e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1720408520 1528 LYDEEVISEDAFYKWesSKDPAEQAGKGVALKSVTAFFTWLREAEEE 1574
Cdd:cd11560 150 LYKADVLSEDAILKW--YKKGHSPKGKQVFLKQMEPFVEWLQEAEEE 194
|
|
| Atrophin-1 super family |
cl38111 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
13-350 |
7.87e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
The actual alignment was detected with superfamily member pfam03154:
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 44.37 E-value: 7.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 13 QRPQIQPPRaaIPNSSPSIRPGVQTPTAVYQANQhimmvnhlPMPYPVTQGHQYCIPQYRHSGPPYVGPPQQYPVqppgp 92
Cdd:pfam03154 233 QTPTLHPQR--LPSPHPPLQPMTQPPPPSQVSPQ--------PLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQP----- 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 93 gpfypGPGPGDFANAYGTPFYPSQPVYQSA--PIIVPTQQQPPPAKREKKTIRIRDPnqggkditeeimsgggsrNPTPP 170
Cdd:pfam03154 298 -----FPLTPQSSQSQVPPGPSPAAPGQSQqrIHTPPSQSQLQSQQPPREQPLPPAP------------------LSMPH 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 171 IGRPASTPTPPQLPSQVPEHSPvvygtvesaHLAASTPVTAASDQkqeekpKPDPVFQSPSTVLRLVLSGEKKEQAGQMP 250
Cdd:pfam03154 355 IKPPPTTPIPQLPNPQSHKHPP---------HLSGPSPFQMNSNL------PPPPALKPLSSLSTHHPPSAHPPPLQLMP 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 251 ETAAGEPTP-EPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKceLPSSKEEDAPPVPSPTScTAASGPSLtdns 329
Cdd:pfam03154 420 QSQQLPPPPaQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPF--VPGGPPPITPPSGPPTS-TSSAMPGI---- 492
|
330 340
....*....|....*....|.
gi 1720408520 330 dicKKPCSVAPHDSQLISSTI 350
Cdd:pfam03154 493 ---QPPSSASVSSSGPVPAAV 510
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
749-977 |
2.06e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.53 E-value: 2.06e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 749 FRKVRSILNKLTPQMFNQLMKQVSALTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLkvpmadkpgNTVNFR 828
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNLR---------NPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 829 KLLLNRCQKEFEKdkadddvfekkqkeleaasapeertrlHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCV 908
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720408520 909 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERK---TSSRIRFMLQDVIDLRLCN 977
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVLSKDdpkLSSRLRFMLQDLIELRKNK 203
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
750-974 |
9.59e-51 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 178.32 E-value: 9.59e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 750 RKVRSILNKLTPQMFNQLMKQVSALTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVtLKVPmadkpgntvNFRK 829
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLN-AKNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 830 LLLNRCQKEFEKDkadddvfekkqkeleaasapeertrlhdeLEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVV 909
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720408520 910 KLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKT---SSRIRFMLQDVIDLR 974
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELR 197
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1417-1549 |
1.90e-48 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 169.00 E-value: 1.90e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1417 EELSQRLEKLIMEEKADDErIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADcSTFRVDTAVIKQRVPILLKYLDSD 1496
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDE-LYKWIKENVSPELYASPGFVRALMTAVLKYAIEEK-SLPEKEKALLEKYAPLLQKYLDDD 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1720408520 1497 TEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPA 1549
Cdd:cd11559 82 EQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1215-1327 |
9.24e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 128.93 E-value: 9.24e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1215 VERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFVKVGVEFTLERSQITRDHMGHLLYQLVQSEKLSKQDFFKGFSE 1294
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1720408520 1295 TLELADDMAIDIPHIWLYLAELVTPMLKGGGIS 1327
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1215-1327 |
3.28e-32 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 121.58 E-value: 3.28e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1215 VERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFVKVGVEFTLERSQITRDHMGHLLYQLVQSEKLSKQDFFKGFSE 1294
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1720408520 1295 TLELADDMAIDIPHIWLYLAELVTPMLKGGGIS 1327
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1487-1571 |
2.69e-28 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 109.30 E-value: 2.69e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1487 PILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEqaGKGVALKSVTAFFT 1566
Cdd:smart00515 1 GPLLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVT 78
|
....*
gi 1720408520 1567 WLREA 1571
Cdd:smart00515 79 WLQEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1500-1576 |
1.03e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 96.06 E-value: 1.03e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720408520 1500 ELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQaGKGVALKSVTAFFTWLREAEEESE 1576
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAEK-GMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
161-324 |
4.66e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 51.39 E-value: 4.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 161 GGGSRNPTPPIGRPASTPTPPQLP--SQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVL 238
Cdd:PRK07003 368 PGGGVPARVAGAVPAPGARAAAAVgaSAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDA 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 239 SGEKKEQAGQMPETAAGEPTPEPPRTSSPTS-----LPPLARSSlPSPMSAALSSQPLFTAEDKCELPSSKEEDAPPVP- 312
Cdd:PRK07003 448 PVPAKANARASADSRCDERDAQPPADSGSASapasdAPPDAAFE-PAPRAAAPSAATPAAVPDARAPAAASREDAPAAAa 526
|
170
....*....|..
gi 1720408520 313 SPTSCTAASGPS 324
Cdd:PRK07003 527 PPAPEARPPTPA 538
|
|
| W2_eIF5C_like |
cd11560 |
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; ... |
1528-1574 |
1.15e-04 |
|
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; eIF5C appears to be essential for the initiation of protein translation; its actual function, and specifically that of the C-terminal W2 domain, are not well understood. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211398 [Multi-domain] Cd Length: 194 Bit Score: 44.90 E-value: 1.15e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1720408520 1528 LYDEEVISEDAFYKWesSKDPAEQAGKGVALKSVTAFFTWLREAEEE 1574
Cdd:cd11560 150 LYKADVLSEDAILKW--YKKGHSPKGKQVFLKQMEPFVEWLQEAEEE 194
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
13-350 |
7.87e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 44.37 E-value: 7.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 13 QRPQIQPPRaaIPNSSPSIRPGVQTPTAVYQANQhimmvnhlPMPYPVTQGHQYCIPQYRHSGPPYVGPPQQYPVqppgp 92
Cdd:pfam03154 233 QTPTLHPQR--LPSPHPPLQPMTQPPPPSQVSPQ--------PLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQP----- 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 93 gpfypGPGPGDFANAYGTPFYPSQPVYQSA--PIIVPTQQQPPPAKREKKTIRIRDPnqggkditeeimsgggsrNPTPP 170
Cdd:pfam03154 298 -----FPLTPQSSQSQVPPGPSPAAPGQSQqrIHTPPSQSQLQSQQPPREQPLPPAP------------------LSMPH 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 171 IGRPASTPTPPQLPSQVPEHSPvvygtvesaHLAASTPVTAASDQkqeekpKPDPVFQSPSTVLRLVLSGEKKEQAGQMP 250
Cdd:pfam03154 355 IKPPPTTPIPQLPNPQSHKHPP---------HLSGPSPFQMNSNL------PPPPALKPLSSLSTHHPPSAHPPPLQLMP 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 251 ETAAGEPTP-EPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKceLPSSKEEDAPPVPSPTScTAASGPSLtdns 329
Cdd:pfam03154 420 QSQQLPPPPaQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPF--VPGGPPPITPPSGPPTS-TSSAMPGI---- 492
|
330 340
....*....|....*....|.
gi 1720408520 330 dicKKPCSVAPHDSQLISSTI 350
Cdd:pfam03154 493 ---QPPSSASVSSSGPVPAAV 510
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
5-340 |
1.86e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.39 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 5 PQARSPFFQRpQIQPPRAAIPNSSPSIRPGVQTPTAVYQANQhimmvnhlpmpyPVTQGHQYCIPqyRHSGPPYVGPPQQ 84
Cdd:PHA03247 2557 PAAPPAAPDR-SVPPPRPAPRPSEPAVTSRARRPDAPPQSAR------------PRAPVDDRGDP--RGPAPPSPLPPDT 2621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 85 YPVQPPGPGPFYPGPGPGDFANAYGTPfyPSQPVYQSAPiivPTQQQPPPAKREKKTIRIRDPNQGgkditeeimsgggs 164
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVPP--PERPRDDPAP---GRVSRPRRARRLGRAAQASSPPQR-------------- 2682
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 165 rnPTPPIGRPASTPT------PPQLPSQVPEHSPVVYGT----VESAHLAASTPVTAAsdqkqeekPKPDPVFQSPSTVL 234
Cdd:PHA03247 2683 --PRRRAARPTVGSLtsladpPPPPPTPEPAPHALVSATplppGPAAARQASPALPAA--------PAPPAVPAGPATPG 2752
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 235 RLVLSGEKKEQAGQMPETAAGEPTPEPPRTSSPTSLPPL--ARSSLPSPMSAALSSQPLfTAEDKCELPSSKEedAPPVP 312
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLseSRESLPSPWDPADPPAAV-LAPAAALPPAASP--AGPLP 2829
|
330 340
....*....|....*....|....*....
gi 1720408520 313 SPTSCTAASGPSLTDNSDICKKPC-SVAP 340
Cdd:PHA03247 2830 PPTSAQPTAPPPPPGPPPPSLPLGgSVAP 2858
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
173-340 |
2.61e-03 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 42.08 E-value: 2.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 173 RPASTPTPPQLPSQVPEHSPVvYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQMPET 252
Cdd:pfam13254 165 KPKAQPSQPAQPAWMKELNKI-RQSRASVDLGRPNSFKEVTPVGLMRSPAPGGHSKSPSVSGISADSSPTKEEPSEEADT 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 253 AAGEPTPEPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKCELPSSK-----EEDAPPVPSPTSCTAASGPSLTD 327
Cdd:pfam13254 244 LSTDKEQSPAPTSASEPPPKTKELPKDSEEPAAPSKSAEASTEKKEPDTESSpetssEKSAPSLLSPVSKASIDKPLSSP 323
|
170
....*....|....
gi 1720408520 328 NSD-ICKKPCSVAP 340
Cdd:pfam13254 324 DRDpLSPKPKPQSP 337
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
749-977 |
2.06e-63 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 214.53 E-value: 2.06e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 749 FRKVRSILNKLTPQMFNQLMKQVSALTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLkvpmadkpgNTVNFR 828
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNLR---------NPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 829 KLLLNRCQKEFEKdkadddvfekkqkeleaasapeertrlHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCV 908
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720408520 909 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERK---TSSRIRFMLQDVIDLRLCN 977
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVLSKDdpkLSSRLRFMLQDLIELRKNK 203
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
750-974 |
9.59e-51 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 178.32 E-value: 9.59e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 750 RKVRSILNKLTPQMFNQLMKQVSALTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVtLKVPmadkpgntvNFRK 829
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLN-AKNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 830 LLLNRCQKEFEKDkadddvfekkqkeleaasapeertrlhdeLEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVV 909
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720408520 910 KLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKT---SSRIRFMLQDVIDLR 974
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELR 197
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1417-1549 |
1.90e-48 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 169.00 E-value: 1.90e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1417 EELSQRLEKLIMEEKADDErIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADcSTFRVDTAVIKQRVPILLKYLDSD 1496
Cdd:cd11559 4 LRVQAELLKLLQEDPNPDE-LYKWIKENVSPELYASPGFVRALMTAVLKYAIEEK-SLPEKEKALLEKYAPLLQKYLDDD 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1720408520 1497 TEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPA 1549
Cdd:cd11559 82 EQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1215-1327 |
9.24e-35 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 128.93 E-value: 9.24e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1215 VERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFVKVGVEFTLERSQITRDHMGHLLYQLVQSEKLSKQDFFKGFSE 1294
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1720408520 1295 TLELADDMAIDIPHIWLYLAELVTPMLKGGGIS 1327
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1215-1327 |
3.28e-32 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 121.58 E-value: 3.28e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1215 VERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFVKVGVEFTLERSQITRDHMGHLLYQLVQSEKLSKQDFFKGFSE 1294
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1720408520 1295 TLELADDMAIDIPHIWLYLAELVTPMLKGGGIS 1327
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1487-1571 |
2.69e-28 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 109.30 E-value: 2.69e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1487 PILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEqaGKGVALKSVTAFFT 1566
Cdd:smart00515 1 GPLLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVT 78
|
....*
gi 1720408520 1567 WLREA 1571
Cdd:smart00515 79 WLQEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1500-1576 |
1.03e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 96.06 E-value: 1.03e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720408520 1500 ELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQaGKGVALKSVTAFFTWLREAEEESE 1576
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAEK-GMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| W2 |
cd11473 |
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of ... |
1417-1543 |
1.92e-18 |
|
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of several translation initiation factors, including the epsilon chain of eIF2b, where it has been found to catalyze the conversion of eIF2.GDP to its active eIF2.GTP form. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211395 Cd Length: 135 Bit Score: 83.29 E-value: 1.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1417 EELSQRLEKLIMEEKADDERIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADCSTF---RVDTAVIKQRVPILLKYL 1493
Cdd:cd11473 4 KKLRDSLLKELEEDKSSDVESVKAAKSKLDLDPISLEEVVKVLLTAVVNAVESADSISLtqkEQLVLVLKKYGPVLRELL 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1720408520 1494 DSDTEKELQALYALQA--SIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWE 1543
Cdd:cd11473 84 KLIKKDQLYLLLKIEKlcLQLKLSELISLLEKILDLLYDADVLSEEAILSWF 135
|
|
| W2_eIF2B_epsilon |
cd11558 |
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a ... |
1457-1576 |
6.73e-15 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a heteropentameric complex which functions as a guanine nucleotide exchange factor in the recycling of eIF-2 during the initiation of translation in eukaryotes. The epsilon and gamma subunits are sequence similar and both are essential in yeast. Epsilon appears to be the catalytically active subunit, with gamma enhancing its activity. The C-terminal domain of the eIF2B epsilon subunit contains bipartite motifs rich in acidic and aromatic residues, which are responsible for the interaction with eIF2. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211396 Cd Length: 169 Bit Score: 74.22 E-value: 6.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1457 RALMTAVCK-AAIIADCSTFRVDTA---VIKQRVPILLKYLDSDTEkELQALYALQASIVKLDQPANLLRMFFDCLYDEE 1532
Cdd:cd11558 47 RAVVKALLElILEVSSTSTAELLEAlkkLLSKWGPLLENYVKSQDD-QVELLLALEEFCLESEEGGPLFAKLLHALYDLD 125
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1720408520 1533 VISEDAFYKWESSKDPAEQAGKGVALKSVTAFFTWLREAEEESE 1576
Cdd:cd11558 126 ILEEEAILEWWEEPDAGADEEMKKVRELVKKFIEWLEEAEEESD 169
|
|
| W2_eIF5 |
cd11561 |
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase ... |
1429-1576 |
1.77e-08 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase acceleration protein (GAP), as well as a GDP dissociation inhibitor (GDI) during translational initiation in eukaryotes. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211399 Cd Length: 157 Bit Score: 55.31 E-value: 1.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1429 EEKADD--ERIFDWVEANLDESQMSSptfLRALMTAV-------CKAAIIADCSTFRVDTA-VIKQRVPILLKYLDSDte 1498
Cdd:cd11561 1 EEEEDErvDELGEFLKKNKDESGLSE---LKEILKEAerldvvkDKAVLVLAEVLFDENIVkEIKKRKALLLKLVTDE-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 1499 kelQALYALQASIVKL--DQPANLLRMF---FDCLYDEEVISEDAFYKW--ESSKDPAEQAGKGVALKSVTAFFTWLREA 1571
Cdd:cd11561 76 ---KAQKALLGGIERFcgKHSPELLKKVpliLKALYDNDILEEEVILKWyeKVSKKYVSKEKSKKVRKAAEPFVEWLEEA 152
|
....*
gi 1720408520 1572 EEESE 1576
Cdd:cd11561 153 EEEEE 157
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
161-324 |
4.66e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 51.39 E-value: 4.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 161 GGGSRNPTPPIGRPASTPTPPQLP--SQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVL 238
Cdd:PRK07003 368 PGGGVPARVAGAVPAPGARAAAAVgaSAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDA 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 239 SGEKKEQAGQMPETAAGEPTPEPPRTSSPTS-----LPPLARSSlPSPMSAALSSQPLFTAEDKCELPSSKEEDAPPVP- 312
Cdd:PRK07003 448 PVPAKANARASADSRCDERDAQPPADSGSASapasdAPPDAAFE-PAPRAAAPSAATPAAVPDARAPAAASREDAPAAAa 526
|
170
....*....|..
gi 1720408520 313 SPTSCTAASGPS 324
Cdd:PRK07003 527 PPAPEARPPTPA 538
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
35-320 |
4.43e-05 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 48.52 E-value: 4.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 35 VQTPTAVYQANQHIMMVNHLPMPYPVTQGHQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFANAYG-TPFY 113
Cdd:PHA03378 574 IQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPLRPIPMRPLRMQPITFNVLVFpTPHQ 653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 114 PSQ---PVYQSAPIIVP-TQQQPPPA------KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGR---PASTPTP 180
Cdd:PHA03378 654 PPQveiTPYKPTWTQIGhIPYQPSPTgantmlPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRarpPAAAPGR 733
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 181 PQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTvlrlvlsgekkeqAGQMPEtaaGEPTPE 260
Cdd:PHA03378 734 ARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPA-------------PQQRPR---GAPTPQ 797
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720408520 261 PPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKCELPSSK-----EEDAP--PVPSPTSCTAA 320
Cdd:PHA03378 798 PPPQAGPTSMQLMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKkpaalERQAAagPTPSPGSGTSD 864
|
|
| W2_eIF5C_like |
cd11560 |
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; ... |
1528-1574 |
1.15e-04 |
|
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; eIF5C appears to be essential for the initiation of protein translation; its actual function, and specifically that of the C-terminal W2 domain, are not well understood. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211398 [Multi-domain] Cd Length: 194 Bit Score: 44.90 E-value: 1.15e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1720408520 1528 LYDEEVISEDAFYKWesSKDPAEQAGKGVALKSVTAFFTWLREAEEE 1574
Cdd:cd11560 150 LYKADVLSEDAILKW--YKKGHSPKGKQVFLKQMEPFVEWLQEAEEE 194
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
10-314 |
1.30e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 47.00 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 10 PFFQRPQIqpPRAAIPNSSPSIR----PGVQTPTAVYQanqhimmvnhlPMPYPVTQGHQYCIPQYRHSGP---PYVGPP 82
Cdd:PRK10263 339 PVTQTPPV--ASVDVPPAQPTVAwqpvPGPQTGEPVIA-----------PAPEGYPQQSQYAQPAVQYNEPlqqPVQPQQ 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 83 QQYPVQPPGPgpfypgpgpgdfanaygtpfyPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEimsgg 162
Cdd:PRK10263 406 PYYAPAAEQP---------------------AQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQ----- 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 163 GSRNPTPPIGRPASTPTPPQLPSQVPEHSPVVYGTVESAHLAASTP------VTAASDQKQEE-----KPKPDPVfqsps 231
Cdd:PRK10263 460 STYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPlyyfeeVEEKRAREREQlaawyQPIPEPV----- 534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 232 tvlrlvlsgekKEQAGQMPETAAGEPTPEPPRTSSPTSLPPLA--RSSLPSPMSAALSSQPLFT-AEDKCELPSSKEEDA 308
Cdd:PRK10263 535 -----------KEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASgvKKATLATGAAATVAAPVFSlANSGGPRPQVKEGIG 603
|
....*.
gi 1720408520 309 PPVPSP 314
Cdd:PRK10263 604 PQLPRP 609
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
172-327 |
1.59e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 46.70 E-value: 1.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 172 GRPASTPTPPQLPSQVPEHSPVVYGTVESAHLAASTPV---TAASDQKQEEKPKPDPVFQSPS------TVLRLVLSGEK 242
Cdd:PHA03307 19 EFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVagaAACDRFEPPTGPPPGPGTEAPAnesrstPTWSLSTLAPA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 243 KEQAGQMPETAAGEPTPEPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKC-ELPSSKEEDAPPVPSPTSCTAAS 321
Cdd:PHA03307 99 SPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAaGASPAAVASDAASSRQAALPLSS 178
|
....*.
gi 1720408520 322 GPSLTD 327
Cdd:PHA03307 179 PEETAR 184
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
161-330 |
4.09e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 4.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 161 GGGSRNPTPPIGRPASTPTPPQLPSQV--PEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRlvl 238
Cdd:PRK12323 368 SGGGAGPATAAAAPVAQPAPAAAAPAAaaPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP--- 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 239 SGEKKEQAGQMPETAAGEPTPEPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKCELPSSKEEDAPPVPSPTSCT 318
Cdd:PRK12323 445 GGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAE 524
|
170
....*....|..
gi 1720408520 319 AASGPSLTDNSD 330
Cdd:PRK12323 525 SIPDPATADPDD 536
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
110-330 |
5.09e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.93 E-value: 5.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 110 TPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIR-----IRDPNQGGKDITEEIMSGGGSRNPTPPIGRP-ASTPTPPQL 183
Cdd:PHA03247 2762 TTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESReslpsPWDPADPPAAVLAPAAALPPAASPAGPLPPPtSAQPTAPPP 2841
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 184 PSQVPEHSPVVYGTVESA------HLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQMPETAAGEP 257
Cdd:PHA03247 2842 PPGPPPPSLPLGGSVAPGgdvrrrPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQP 2921
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 258 TPEPP-RTSSPTSLPPLARSSLPSPMSAALSSQPLFTAED---------KCELPSSK-EEDAPPVPSPtsctAASGPSLT 326
Cdd:PHA03247 2922 QPPPPpQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQpwlgalvpgRVAVPRFRvPQPAPSREAP----ASSTPPLT 2997
|
....
gi 1720408520 327 DNSD 330
Cdd:PHA03247 2998 GHSL 3001
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
13-350 |
7.87e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 44.37 E-value: 7.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 13 QRPQIQPPRaaIPNSSPSIRPGVQTPTAVYQANQhimmvnhlPMPYPVTQGHQYCIPQYRHSGPPYVGPPQQYPVqppgp 92
Cdd:pfam03154 233 QTPTLHPQR--LPSPHPPLQPMTQPPPPSQVSPQ--------PLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQP----- 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 93 gpfypGPGPGDFANAYGTPFYPSQPVYQSA--PIIVPTQQQPPPAKREKKTIRIRDPnqggkditeeimsgggsrNPTPP 170
Cdd:pfam03154 298 -----FPLTPQSSQSQVPPGPSPAAPGQSQqrIHTPPSQSQLQSQQPPREQPLPPAP------------------LSMPH 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 171 IGRPASTPTPPQLPSQVPEHSPvvygtvesaHLAASTPVTAASDQkqeekpKPDPVFQSPSTVLRLVLSGEKKEQAGQMP 250
Cdd:pfam03154 355 IKPPPTTPIPQLPNPQSHKHPP---------HLSGPSPFQMNSNL------PPPPALKPLSSLSTHHPPSAHPPPLQLMP 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 251 ETAAGEPTP-EPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKceLPSSKEEDAPPVPSPTScTAASGPSLtdns 329
Cdd:pfam03154 420 QSQQLPPPPaQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPF--VPGGPPPITPPSGPPTS-TSSAMPGI---- 492
|
330 340
....*....|....*....|.
gi 1720408520 330 dicKKPCSVAPHDSQLISSTI 350
Cdd:pfam03154 493 ---QPPSSASVSSSGPVPAAV 510
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
114-240 |
9.30e-04 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 43.13 E-value: 9.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 114 PSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDP---------NQGGKDITEEIMSGGGSRNPTPP--------IGRPAS 176
Cdd:PRK11901 113 TAPPQDISAPPISPTPTQAAPPQTPNGQQRIELPgnisdalsqQQGQVNAASQNAQGNTSTLPTAPatvapskgAKVPAT 192
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720408520 177 TPTPPQLPSQVPEHSPVVygtveSAHLAASTPVTAASDQKQEEKPKPDPVFQS-PSTVLRLVLSG 240
Cdd:PRK11901 193 AETHPTPPQKPATKKPAV-----NHHKTATVAVPPATSGKPKSGAASARALSSaPASHYTLQLSS 252
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
160-324 |
9.82e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 9.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 160 SGGGSRNPTPPIGRPASTPTPPQLPSQVPEHSPVVyGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLS 239
Cdd:PRK07764 601 PAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAA-PAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPA 679
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 240 GEKKEQAGQMPETAAGEPTPEP----------PRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKCELPSSKEEDAP 309
Cdd:PRK07764 680 APPPAPAPAAPAAPAGAAPAQPapapaatppaGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPP 759
|
170
....*....|....*
gi 1720408520 310 PVPSPTSCTAASGPS 324
Cdd:PRK07764 760 PPPAPAPAAAPAAAP 774
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
5-340 |
1.86e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.39 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 5 PQARSPFFQRpQIQPPRAAIPNSSPSIRPGVQTPTAVYQANQhimmvnhlpmpyPVTQGHQYCIPqyRHSGPPYVGPPQQ 84
Cdd:PHA03247 2557 PAAPPAAPDR-SVPPPRPAPRPSEPAVTSRARRPDAPPQSAR------------PRAPVDDRGDP--RGPAPPSPLPPDT 2621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 85 YPVQPPGPGPFYPGPGPGDFANAYGTPfyPSQPVYQSAPiivPTQQQPPPAKREKKTIRIRDPNQGgkditeeimsgggs 164
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVPP--PERPRDDPAP---GRVSRPRRARRLGRAAQASSPPQR-------------- 2682
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 165 rnPTPPIGRPASTPT------PPQLPSQVPEHSPVVYGT----VESAHLAASTPVTAAsdqkqeekPKPDPVFQSPSTVL 234
Cdd:PHA03247 2683 --PRRRAARPTVGSLtsladpPPPPPTPEPAPHALVSATplppGPAAARQASPALPAA--------PAPPAVPAGPATPG 2752
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 235 RLVLSGEKKEQAGQMPETAAGEPTPEPPRTSSPTSLPPL--ARSSLPSPMSAALSSQPLfTAEDKCELPSSKEedAPPVP 312
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLseSRESLPSPWDPADPPAAV-LAPAAALPPAASP--AGPLP 2829
|
330 340
....*....|....*....|....*....
gi 1720408520 313 SPTSCTAASGPSLTDNSDICKKPC-SVAP 340
Cdd:PHA03247 2830 PPTSAQPTAPPPPPGPPPPSLPLGgSVAP 2858
|
|
| DUF4045 |
pfam13254 |
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ... |
173-340 |
2.61e-03 |
|
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.
Pssm-ID: 433066 [Multi-domain] Cd Length: 415 Bit Score: 42.08 E-value: 2.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 173 RPASTPTPPQLPSQVPEHSPVvYGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQMPET 252
Cdd:pfam13254 165 KPKAQPSQPAQPAWMKELNKI-RQSRASVDLGRPNSFKEVTPVGLMRSPAPGGHSKSPSVSGISADSSPTKEEPSEEADT 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 253 AAGEPTPEPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFTAEDKCELPSSK-----EEDAPPVPSPTSCTAASGPSLTD 327
Cdd:pfam13254 244 LSTDKEQSPAPTSASEPPPKTKELPKDSEEPAAPSKSAEASTEKKEPDTESSpetssEKSAPSLLSPVSKASIDKPLSSP 323
|
170
....*....|....
gi 1720408520 328 NSD-ICKKPCSVAP 340
Cdd:pfam13254 324 DRDpLSPKPKPQSP 337
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
110-295 |
3.36e-03 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 41.57 E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 110 TPFYPSQpvyqsapiiVPTQQQPPPAKREKKTIRIRDPNQGgkditeeimSGGGSRNPTPPIGRPASTPTPPQL-PSQVP 188
Cdd:pfam05539 186 HPTYPSQ---------VTPQSQPATQGHQTATANQRLSSTE---------PVGTQGTTTSSNPEPQTEPPPSQRgPSGSP 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 189 EHSPvvygtvesahlaaSTP----VTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKeqagqmPETAAGEPTPEPPRT 264
Cdd:pfam05539 248 QHPP-------------STTsqdqSTTGDGQEHTQRRKTPPATSNRRSPHSTATPPPTT------KRQETGRPTPRPTAT 308
|
170 180 190
....*....|....*....|....*....|.
gi 1720408520 265 SSPTSLPPlarSSLPSPMSAALSSQPLFTAE 295
Cdd:pfam05539 309 TQSGSSPP---HSSPPGVQANPTTQNLVDCK 336
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
114-262 |
3.47e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.14 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 114 PSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPigrPASTPTPPQLPSQVPEHSPV 193
Cdd:PRK07003 467 DAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPA---AAAPPAPEARPPTPAAAAPA 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 194 VYGTVESAHL-----------------AASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQMPEtAAGE 256
Cdd:PRK07003 544 ARAGGAAAALdvlrnagmrvssdrgarAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQ-AAES 622
|
....*.
gi 1720408520 257 PTPEPP 262
Cdd:PRK07003 623 RGAPPP 628
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
114-316 |
5.53e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 41.45 E-value: 5.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 114 PSQPVYQSAPIiVPTQQQPPPAKREKKtiRIRDPNQGGKDITEEImsgggSRNPTPPIGRPAS--------------TPT 179
Cdd:PLN03209 343 PTKPVTPEAPS-PPIEEEPPQPKAVVP--RPLSPYTAYEDLKPPT-----SPIPTPPSSSPASsksvdavakpaepdVVP 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720408520 180 PPQLPSQVPEHSPvvyGTVESAHLAASTPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQMPETAAGEPTP 259
Cdd:PLN03209 415 SPGSASNVPEVEP---AQVEAKKTRPLSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPP 491
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720408520 260 EPPRTSS----------PTSLPPLARSSLPSPMSAALSSQPLFTAEDKCelPSSKEEDAPPVPSPTS 316
Cdd:PLN03209 492 ANMRPLSpyavyddlkpPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTA--LADEQHHAQPKPRPLS 556
|
|
| |
