artemin isoform X1 [Mus musculus]
TGF-beta family protein( domain architecture ID 14443713)
transforming growth factor-beta (TGF-beta) family protein may control proliferation, differentiation, and other functions in many cell types
List of domain hits
Name | Accession | Description | Interval | E-value | |||
TGF_beta_Artemin | cd19381 | transforming growth factor beta (TGF-beta) like domain found in Artemin and similar proteins; ... |
126-223 | 1.19e-53 | |||
transforming growth factor beta (TGF-beta) like domain found in Artemin and similar proteins; Artemin, also termed Enovin, or Neublastin, is a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. It acts as the ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. It supports peripheral and central neurons and signals through the GFR-alpha-3-RET receptor complex. : Pssm-ID: 381651 Cd Length: 98 Bit Score: 167.53 E-value: 1.19e-53
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Name | Accession | Description | Interval | E-value | |||
TGF_beta_Artemin | cd19381 | transforming growth factor beta (TGF-beta) like domain found in Artemin and similar proteins; ... |
126-223 | 1.19e-53 | |||
transforming growth factor beta (TGF-beta) like domain found in Artemin and similar proteins; Artemin, also termed Enovin, or Neublastin, is a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. It acts as the ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. It supports peripheral and central neurons and signals through the GFR-alpha-3-RET receptor complex. Pssm-ID: 381651 Cd Length: 98 Bit Score: 167.53 E-value: 1.19e-53
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TGF_beta | pfam00019 | Transforming growth factor beta like domain; |
126-222 | 2.85e-15 | |||
Transforming growth factor beta like domain; Pssm-ID: 459632 Cd Length: 102 Bit Score: 68.89 E-value: 2.85e-15
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Name | Accession | Description | Interval | E-value | |||
TGF_beta_Artemin | cd19381 | transforming growth factor beta (TGF-beta) like domain found in Artemin and similar proteins; ... |
126-223 | 1.19e-53 | |||
transforming growth factor beta (TGF-beta) like domain found in Artemin and similar proteins; Artemin, also termed Enovin, or Neublastin, is a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. It acts as the ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. It supports peripheral and central neurons and signals through the GFR-alpha-3-RET receptor complex. Pssm-ID: 381651 Cd Length: 98 Bit Score: 167.53 E-value: 1.19e-53
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TGF_beta_GDNF_like | cd13750 | transforming growth factor beta (TGF-beta) like domain found in the glial cell-line-derived ... |
126-222 | 7.63e-40 | |||
transforming growth factor beta (TGF-beta) like domain found in the glial cell-line-derived neurotrophic factor (GDNF) family of ligands; GDNF family of ligands includes GDNF, Artemin, Neurturin, and Persephin. They plays an important role in the development and maintenance of the central and peripheral nervous system, renal morphogenesis, and spermatogenesis. Pssm-ID: 381628 Cd Length: 95 Bit Score: 132.19 E-value: 7.63e-40
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TGF_beta_Persephin | cd19382 | transforming growth factor beta (TGF-beta) like domain found in Persephin and similar proteins; ... |
125-224 | 2.41e-33 | |||
transforming growth factor beta (TGF-beta) like domain found in Persephin and similar proteins; Persephin is a member of the glial cell-line-derived neurotrophic factor (GDNF) family with neurotrophic activity on mesencephalic dopaminergic and motor neurons. Pssm-ID: 381652 Cd Length: 99 Bit Score: 115.64 E-value: 2.41e-33
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TGF_beta_Neurturin | cd19383 | transforming growth factor beta (TGF-beta) like domain found in Neurturin and similar proteins; ... |
124-222 | 6.60e-29 | |||
transforming growth factor beta (TGF-beta) like domain found in Neurturin and similar proteins; Neurturin is a member of the glial cell-line-derived neurotrophic factor (GDNF) family. It acts as a neurotrophic factor that supports the survival of sympathetic neurons in culture and may regulate the development and maintenance of the CNS. It might control the size of non-neuronal cell population such as haemopoietic cells. Pssm-ID: 381653 Cd Length: 104 Bit Score: 104.39 E-value: 6.60e-29
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TGF_beta_GDNF | cd19380 | transforming growth factor beta (TGF-beta) like domain found in glial cell line-derived ... |
125-222 | 5.89e-17 | |||
transforming growth factor beta (TGF-beta) like domain found in glial cell line-derived neurotrophic factor (GDNF) and similar proteins; GDNF, also termed astrocyte-derived trophic factor (ATF), is a member of the glial cell-line-derived neurotrophic factor (GDNF) family. It acts as a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Pssm-ID: 381650 Cd Length: 96 Bit Score: 73.34 E-value: 5.89e-17
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TGF_beta | pfam00019 | Transforming growth factor beta like domain; |
126-222 | 2.85e-15 | |||
Transforming growth factor beta like domain; Pssm-ID: 459632 Cd Length: 102 Bit Score: 68.89 E-value: 2.85e-15
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TGF_beta_BMPs_GDFs | cd13756 | transforming growth factor beta (TGF-beta) like domain found in the BMP/GDF family; The BMP ... |
127-222 | 2.71e-10 | |||
transforming growth factor beta (TGF-beta) like domain found in the BMP/GDF family; The BMP/GDF family consists of bone morphogenetic proteins (BMPs), growth and differentiation factors (GDFs) and similar proteins. BMPs are a group of growth factors also known as cytokines and as metabologens. They induce the formation of bone and cartilage and functions as pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. GDFs have functions predominantly in development. Pssm-ID: 381634 Cd Length: 102 Bit Score: 55.40 E-value: 2.71e-10
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TGF_beta_SF | cd08698 | transforming growth factor beta (TGF-beta) like domain found in TGF-beta superfamily; TGF-beta ... |
127-222 | 3.33e-08 | |||
transforming growth factor beta (TGF-beta) like domain found in TGF-beta superfamily; TGF-beta superfamily consists of a large group of cell regulatory proteins, such as TFG-betas, Nodal, Activins/Inhibins, glial cell-line-derived neurotrophic factor (GDNF) family of ligands, bone morphogenetic proteins (BMPs), and growth and differentiation factors (GDFs). They play important roles in developmental and physiological processes in a variety of species, including invertebrates as well as vertebrates, through specific receptor complexes that are composed of type I and type II serine/threonine receptor kinases. The receptor kinases subsequently activate Smad proteins, which then propagate the signals into the nucleus to regulate target gene expression. Proteins from the TGF-beta superfamily are only active as homo- or heterodimer. Pssm-ID: 381627 Cd Length: 100 Bit Score: 49.78 E-value: 3.33e-08
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TGF_beta_DAF7 | cd19378 | transforming growth factor beta (TGF-beta) like domain found in Caenorhabditis elegans Dauer ... |
151-222 | 1.28e-04 | |||
transforming growth factor beta (TGF-beta) like domain found in Caenorhabditis elegans Dauer larva development regulatory growth factor DAF-7 and similar proteins; DAF-7, also termed abnormal dauer formation protein 7, may act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons. It is involved in sensitivity to CO2 levels. Pssm-ID: 381648 Cd Length: 100 Bit Score: 40.01 E-value: 1.28e-04
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TGF_beta_INHB | cd13752 | transforming growth factor beta (TGF-beta) like domain found in inhibin beta A chain (INHBA), ... |
153-222 | 4.27e-03 | |||
transforming growth factor beta (TGF-beta) like domain found in inhibin beta A chain (INHBA), B chain (INHBB), C chain (INHBC), E chain (INHBE) and similar proteins; The family includes inhibin beta A chain (INHBA), B chain (INHBB), C chain (INHBC), and E chain (INHBE). INHBA, also termed activin beta-A chain, or erythroid differentiation protein (EDF), is a component of inhibin A, activin A, or activin AB. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. INHBB, also termed activin beta-B chain, is a component of inhibin B, activin A, or activin AB. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. INHBC, also termed activin beta-C chain, might play important roles in carcinogenesis. It may function as a negative regulator of liver growth. INHBE, also termed activin beta-E chain, is a possible insulin resistance-associated hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. It also acts as a possible new marker for drug-induced endoplasmic reticulum stress. Pssm-ID: 381630 Cd Length: 100 Bit Score: 35.71 E-value: 4.27e-03
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TGF_beta_TGFbeta1_2_3 | cd13753 | transforming growth factor beta (TGF-beta) like domain found in transforming growth factor ... |
149-222 | 6.36e-03 | |||
transforming growth factor beta (TGF-beta) like domain found in transforming growth factor beta-1 (TGF-beta-1), beta-2 (TGF-beta-2), beta-3 (TGF-beta-3) and similar proteins; The family includes TGF-beta-1, TGF-beta-2 and TGF-beta-3, which are polypeptide members of the transforming growth factor beta superfamily of cytokines. TGF-beta-1 is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. TGF-beta-2 is a secreted protein that performs many cellular functions and has a vital role during embryonic development. It can suppress the effects of interleukin-2 dependent T-cell growth. TGF-beta-3 is involved in embryogenesis and cell differentiation. It regulates molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. Pssm-ID: 381631 Cd Length: 97 Bit Score: 34.98 E-value: 6.36e-03
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