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Conserved domains on  [gi|1720390625|ref|XP_030105765|]
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A-kinase anchor protein 8-like isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AKAP95 super family cl04876
A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is ...
 414-512 2.79e-46

A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. The protein contains two zinc fingers which are thought to mediate the binding of AKAP95 to DNA.


The actual alignment was detected with superfamily member pfam04988:

Pssm-ID: 461509  Cd Length: 136  Bit Score: 158.02  E-value: 2.79e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720390625 414 KEHFKYV--GTKLPKQTADFLQEYVTNKTKKTEELRKTVEDLDGLIQQiyRDQDLTQEIAMEHFVKKVEAAHCAACDLFI 491
Cdd:pfam04988   1 KETLDYIqkQTKFDKVVMEFLHECMVNKFKKTEERRQQLNDLESVKKQ--IEKDVMEGVTEEDFMKKVEAAHCAACDLLI 78

                          90       100
                  ....*....|....*....|.
gi 1720390625 492 PMQFGIIQKHLKTMDHNRNRR 512
Cdd:pfam04988  79 PAQFSSVQQHLKSADHNKNKR 99
 
Name Accession Description Interval E-value
AKAP95 pfam04988
A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is ...
 414-512 2.79e-46

A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. The protein contains two zinc fingers which are thought to mediate the binding of AKAP95 to DNA.


Pssm-ID: 461509  Cd Length: 136  Bit Score: 158.02  E-value: 2.79e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720390625 414 KEHFKYV--GTKLPKQTADFLQEYVTNKTKKTEELRKTVEDLDGLIQQiyRDQDLTQEIAMEHFVKKVEAAHCAACDLFI 491
Cdd:pfam04988   1 KETLDYIqkQTKFDKVVMEFLHECMVNKFKKTEERRQQLNDLESVKKQ--IEKDVMEGVTEEDFMKKVEAAHCAACDLLI 78

                          90       100
                  ....*....|....*....|.
gi 1720390625 492 PMQFGIIQKHLKTMDHNRNRR 512
Cdd:pfam04988  79 PAQFSSVQQHLKSADHNKNKR 99
 
Name Accession Description Interval E-value
AKAP95 pfam04988
A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is ...
 414-512 2.79e-46

A-kinase anchoring protein 95 (AKAP95); A-kinase (or PKA)-anchoring protein AKAP95 is implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. The protein contains two zinc fingers which are thought to mediate the binding of AKAP95 to DNA.


Pssm-ID: 461509  Cd Length: 136  Bit Score: 158.02  E-value: 2.79e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720390625 414 KEHFKYV--GTKLPKQTADFLQEYVTNKTKKTEELRKTVEDLDGLIQQiyRDQDLTQEIAMEHFVKKVEAAHCAACDLFI 491
Cdd:pfam04988   1 KETLDYIqkQTKFDKVVMEFLHECMVNKFKKTEERRQQLNDLESVKKQ--IEKDVMEGVTEEDFMKKVEAAHCAACDLLI 78

                          90       100
                  ....*....|....*....|.
gi 1720390625 492 PMQFGIIQKHLKTMDHNRNRR 512
Cdd:pfam04988  79 PAQFSSVQQHLKSADHNKNKR 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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