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Conserved domains on  [gi|1720385240|ref|XP_030104666|]
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5-oxoprolinase isoform X3 [Mus musculus]

Protein Classification

hydantoinase/oxoprolinase family protein( domain architecture ID 1004610)

hydantoinase/oxoprolinase family protein is involved in the hydrolysis of 5-membered rings via hydrolysis of their internal imide bonds; such as 5-oxoprolinase that catalyzes the hydrolysis of 5-oxoproline (5-OP) to L-glutamate

EC:  3.5.2.-
Gene Ontology:  GO:0005524|GO:0016812

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PLN02666 super family cl33539
5-oxoprolinase
1-1258 0e+00

5-oxoprolinase


The actual alignment was detected with superfamily member PLN02666:

Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1904.83  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240    1 MGSPEER-FHFAIDRGGTFTDVFAQCPGG-HVRVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIR 78
Cdd:PLN02666     2 MGSRGSRkFRFCIDRGGTFTDVYAEVPGGsDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEWIR 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240   79 MGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRGEPGA---GSPVKG 155
Cdd:PLN02666    82 MGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVLALEEDGDdagGSVVKG 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  156 CTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTA 235
Cdd:PLN02666   162 VTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSSALVPMVRAVPRGHTA 241
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  236 CADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDM 315
Cdd:PLN02666   242 SVDAYLTPVIKEYLSGFLSGFDDGLGDVNVLFMQSDGGLTPESRFSGHKAILSGPAGGVVGYAQTTFGLETEKPVIGFDM 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  316 GGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDAN 395
Cdd:PLN02666   322 GGTSTDVSRYDGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFRVGPESVGAHPGPVCYRKGGELAVTDAN 401
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  396 LVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCPASQLSLEEVAMGFVRVANEAMCRPIRALTQA 475
Cdd:PLN02666   402 LVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSAKDMSVEEVALGFVRVANEAMCRPIRQLTEM 481
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  476 RGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLE 555
Cdd:PLN02666   482 KGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVVAEAQEPYAAVYGPESLAEASRREDALA 561
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  556 EQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSanQHPATTCSPraGDFGAAFVERYMREFGFIIPERSVVVDDVR 635
Cdd:PLN02666   562 EKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVA--EPENGDGSD--GDYAAAFVKLFRREYGFKLQNRDILIDDVR 637
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  636 VRGTGRSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIET 714
Cdd:PLN02666   638 VRGIGVTNiLKPLPLDAASGGLPEPERTTKVYFENGWHDTPVYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKY 717
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  715 GDIRISVG-------AEAPSMIDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAP 787
Cdd:PLN02666   718 GNIKIEVEnsaeqsaEETVKAAEKKADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAP 797
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  788 HIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSM 867
Cdd:PLN02666   798 HVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSHLPDITVITPVFRDG--KIVFFVASRGHHADIGGITPGSM 875
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  868 PPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQAPGKISGC---SGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQY 944
Cdd:PLN02666   876 PPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQAPGSDETApkiPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEY 955
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  945 GLDVVQAYMGHIQANAELAVRDMLRAFGT--SRQARGLPLEVS----AKDHMDDGSPICLHVQINLNQGSAVFDFSGSGS 1018
Cdd:PLN02666   956 GLGTVQAYMGHVQANAELAVREMLKSVAArvSSESPTFGDGSSvtleAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSP 1035
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1019 EVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACA 1098
Cdd:PLN02666  1036 EVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRIPPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACA 1115
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1099 ASQGCMNNVTLGNARMGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRPGSGGRGRFRGGD 1178
Cdd:PLN02666  1116 CSQGCMNNLTFGDDTFGYYETIAGGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGD 1195
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1179 GVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPED 1258
Cdd:PLN02666  1196 GVVREIEFRRPVTVSILSERRVHAPRGLAGGGDGARGANLLIRKDGRRVNLGGKNTVHVEAGERLRILTPGGGGYGSKPS 1275
 
Name Accession Description Interval E-value
PLN02666 PLN02666
5-oxoprolinase
1-1258 0e+00

5-oxoprolinase


Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1904.83  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240    1 MGSPEER-FHFAIDRGGTFTDVFAQCPGG-HVRVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIR 78
Cdd:PLN02666     2 MGSRGSRkFRFCIDRGGTFTDVYAEVPGGsDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEWIR 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240   79 MGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRGEPGA---GSPVKG 155
Cdd:PLN02666    82 MGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVLALEEDGDdagGSVVKG 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  156 CTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTA 235
Cdd:PLN02666   162 VTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSSALVPMVRAVPRGHTA 241
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  236 CADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDM 315
Cdd:PLN02666   242 SVDAYLTPVIKEYLSGFLSGFDDGLGDVNVLFMQSDGGLTPESRFSGHKAILSGPAGGVVGYAQTTFGLETEKPVIGFDM 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  316 GGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDAN 395
Cdd:PLN02666   322 GGTSTDVSRYDGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFRVGPESVGAHPGPVCYRKGGELAVTDAN 401
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  396 LVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCPASQLSLEEVAMGFVRVANEAMCRPIRALTQA 475
Cdd:PLN02666   402 LVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSAKDMSVEEVALGFVRVANEAMCRPIRQLTEM 481
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  476 RGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLE 555
Cdd:PLN02666   482 KGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVVAEAQEPYAAVYGPESLAEASRREDALA 561
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  556 EQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSanQHPATTCSPraGDFGAAFVERYMREFGFIIPERSVVVDDVR 635
Cdd:PLN02666   562 EKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVA--EPENGDGSD--GDYAAAFVKLFRREYGFKLQNRDILIDDVR 637
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  636 VRGTGRSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIET 714
Cdd:PLN02666   638 VRGIGVTNiLKPLPLDAASGGLPEPERTTKVYFENGWHDTPVYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKY 717
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  715 GDIRISVG-------AEAPSMIDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAP 787
Cdd:PLN02666   718 GNIKIEVEnsaeqsaEETVKAAEKKADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAP 797
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  788 HIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSM 867
Cdd:PLN02666   798 HVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSHLPDITVITPVFRDG--KIVFFVASRGHHADIGGITPGSM 875
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  868 PPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQAPGKISGC---SGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQY 944
Cdd:PLN02666   876 PPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQAPGSDETApkiPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEY 955
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  945 GLDVVQAYMGHIQANAELAVRDMLRAFGT--SRQARGLPLEVS----AKDHMDDGSPICLHVQINLNQGSAVFDFSGSGS 1018
Cdd:PLN02666   956 GLGTVQAYMGHVQANAELAVREMLKSVAArvSSESPTFGDGSSvtleAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSP 1035
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1019 EVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACA 1098
Cdd:PLN02666  1036 EVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRIPPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACA 1115
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1099 ASQGCMNNVTLGNARMGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRPGSGGRGRFRGGD 1178
Cdd:PLN02666  1116 CSQGCMNNLTFGDDTFGYYETIAGGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGD 1195
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1179 GVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPED 1258
Cdd:PLN02666  1196 GVVREIEFRRPVTVSILSERRVHAPRGLAGGGDGARGANLLIRKDGRRVNLGGKNTVHVEAGERLRILTPGGGGYGSKPS 1275
Hydantoinase_B pfam02538
Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts ...
735-1256 0e+00

Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts hydantoin to N-carbamyl-amino acids, and 5-oxoprolinase EC:3.5.2.9 which catalyzes the formation of L-glutamate from 5-oxo-L-proline. These enzymes are part of the oxoprolinase family and are related to pfam01968.


Pssm-ID: 460583  Cd Length: 507  Bit Score: 687.28  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  735 PIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGaDLHPG 814
Cdd:pfam02538    1 PITLEVFRNRLMSIAEEMGRTLQRTAFSPNIKERLDFSCAIFDADGRLVAQAPHIPVHLGSMSFAVKAVIEYGG-DLRPG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  815 DVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVfQE 894
Cdd:pfam02538   80 DVFITNDPYAGGTHLPDITVITPVFHDG--ELVFFVASRGHHADIGGIVPGSMPPDATEIYQEGLRIPPVKLVRRGV-LN 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  895 EAVTEALqapgkisgCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAfgts 974
Cdd:pfam02538  157 EDVLRLL--------LANSRTPEDNLGDLKAQIAANRVGERRLLELIDEYGLDTVLAAMDEIQDYAERAVRAAIAA---- 224
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  975 rqargLPL-EVSAKDHMDDGSPICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGC 1053
Cdd:pfam02538  225 -----LPDgTYEAEDYLDDGVPIPIRVTVTIDGDEATVDFTGTSPQVPGNINAPLAVTHSAVIYALRCLVDPDIPLNAGC 299
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1054 LAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFG------ACAASQGCMNNVTLG-------NARMGYYETV 1120
Cdd:pfam02538  300 LRPIEVIAPEGSLLNPSPPAAVVGGNVETSQRIVDVVLGALAqalperVPAASQGTMNNLTFGgvdprggGRFFGYYETI 379
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1121 AGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELrpgsggrgrfrggDG-------------VVRELVFR 1187
Cdd:pfam02538  380 GGGSGARPGGDGLDGVHVHMTNTRNTPVEVLERRYPVLVERYEL-------------RPdsggagryrggdgVVREIEFL 446
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1188 E-EALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKdgrtvnlggKTSVTVYPGDAFCLHTPGGGGYGDP 1256
Cdd:pfam02538  447 ApDATVSILSERRVFPPWGLAGGEPGAPGRVNLGGK---------ATDVELKPGDRLRIETPGGGGYGDP 507
HyuA COG0145
N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport ...
10-725 0e+00

N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439915 [Multi-domain]  Cd Length: 678  Bit Score: 646.38  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240   10 FAIDRGGTFTDVFAQCPGGHVRVLKLLSeDPANYADAPTEGIRRILEQErgvllprgrPLDTSHIASIRMGTTVATNALL 89
Cdd:COG0145      1 VGVDVGGTFTDVVAVDEDGRLRTHKVLS-TPEDPSDGVLEGIRELLEDA---------GIPLAEIDLVVHGTTVATNALL 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240   90 ERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEvlyeevvevdervLLYRGEPgagspVKGCTGDLL---EIQQP 166
Cdd:COG0145     71 ERKGARTGLITTRGFRDVLEIGRQNRPDLYDLFIEKPE-------------PLVPRRL-----RFEVRERIDadgEVLTP 132
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  167 VDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARE-LGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTI 245
Cdd:COG0145    133 LDEAEVRAAARELRAAGVEAVAVCFLHSYRNPAHERRAAEILREeLPDVPVSLSSEVSPEIREYERTSTTVVNAYLSPIL 212
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  246 QRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFS--GSRAVLSGPAGGVVGySTTTYQLEGGQPVIGFDMGGTSTDVS 323
Cdd:COG0145    213 RRYLDRLEARLRERGFGGPLLIMQSNGGLASAEAAArrPVRTILSGPAGGVVG-AAALARAAGFDNVITFDMGGTSTDVS 291
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  324 RYA-GEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFF-RSGLFVVGPESAGAHPGPACYRKGGP-VTVTDANLVLGR 400
Cdd:COG0145    292 LIEdGEPERTTETEVAGYPVRVPMVDIHTVGAGGGSIAWVdAGGRLRVGPESAGADPGPACYGRGGTePTVTDANLVLGR 371
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  401 LLPASFPcifgpGEDQPLSPEASRKALEAVAMEVNsflasgpcpasqLSLEEVAMGFVRVANEAMCRPIRALTQARGHDP 480
Cdd:COG0145    372 LDPDNFL-----GGRMPLDVEAARAAIEKLADPLG------------LSVEEAAEGILRIANENMANAIRKVSVERGYDP 434
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  481 SAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLEEQCVD 560
Cdd:COG0145    435 RDFTLVAFGGAGPLHACALAEELGIPRVIVPPAAGVLSALGMLLADIRHDYVRSVEAPLDDADLAELNAAFAELEAEARA 514
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  561 ALQAQGFSRSQISTESFLHLRYQGTDCALMVSANQHPATTCSprAGDFGAAFVERYMREFGFIIPERSVVVDDVRVRGTG 640
Cdd:COG0145    515 ELAAEGVAAEDIRVERSADMRYAGQGHELTVPLPAGRLDAAD--LAALRAAFHAAHERRYGFALPDAPVEIVNLRVEAIG 592
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  641 RSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIETGDIRI 719
Cdd:COG0145    593 PVPkPELPRLPPGGDAAPAPKGTRPVYFDGGWVDTPVYDREALPPGDRIAGPAIIEEPDTTTVVPPGWRATVDAYGNLIL 672

                   ....*.
gi 1720385240  720 SVGAEA 725
Cdd:COG0145    673 TRAAAA 678
 
Name Accession Description Interval E-value
PLN02666 PLN02666
5-oxoprolinase
1-1258 0e+00

5-oxoprolinase


Pssm-ID: 215358 [Multi-domain]  Cd Length: 1275  Bit Score: 1904.83  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240    1 MGSPEER-FHFAIDRGGTFTDVFAQCPGG-HVRVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIR 78
Cdd:PLN02666     2 MGSRGSRkFRFCIDRGGTFTDVYAEVPGGsDFRVLKLLSVDPANYDDAPREGIRRILEEVTGKKIPRSAKIPTERIEWIR 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240   79 MGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRGEPGA---GSPVKG 155
Cdd:PLN02666    82 MGTTVATNALLERKGERIALCVTKGFKDLLQIGNQARPNIFDLTVSKPSNLYEEVVEVDERVVLALEEDGDdagGSVVKG 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  156 CTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTA 235
Cdd:PLN02666   162 VTGELVEVVKPLDEEALRPLLQGLLDKGIRSLAVVLMHSYTYPAHERAVGKLARSMGFKQVSLSSALVPMVRAVPRGHTA 241
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  236 CADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDM 315
Cdd:PLN02666   242 SVDAYLTPVIKEYLSGFLSGFDDGLGDVNVLFMQSDGGLTPESRFSGHKAILSGPAGGVVGYAQTTFGLETEKPVIGFDM 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  316 GGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDAN 395
Cdd:PLN02666   322 GGTSTDVSRYDGSYEQVLETQTAGVIIQAPQLDINTVAAGGGSKLKFQFGAFRVGPESVGAHPGPVCYRKGGELAVTDAN 401
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  396 LVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCPASQLSLEEVAMGFVRVANEAMCRPIRALTQA 475
Cdd:PLN02666   402 LVLGRVIPDYFPSIFGPNEDEPLDLEATRAAFEALAAQINSYRKSQDPSAKDMSVEEVALGFVRVANEAMCRPIRQLTEM 481
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  476 RGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLE 555
Cdd:PLN02666   482 KGYETANHALACFGGAGPQHACAIARALGMSEVFVHRYCGILSAYGMGLADVVAEAQEPYAAVYGPESLAEASRREDALA 561
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  556 EQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSanQHPATTCSPraGDFGAAFVERYMREFGFIIPERSVVVDDVR 635
Cdd:PLN02666   562 EKVRQKLQEQGFREDNITTETYLNLRYEGTDTAIMVA--EPENGDGSD--GDYAAAFVKLFRREYGFKLQNRDILIDDVR 637
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  636 VRGTGRSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIET 714
Cdd:PLN02666   638 VRGIGVTNiLKPLPLDAASGGLPEPERTTKVYFENGWHDTPVYKLENLGPGHEIPGPAIIMNGNSTVVVEPGCKAIVTKY 717
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  715 GDIRISVG-------AEAPSMIDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAP 787
Cdd:PLN02666   718 GNIKIEVEnsaeqsaEETVKAAEKKADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKERLDFSCALFGPDGGLVANAP 797
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  788 HIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSM 867
Cdd:PLN02666   798 HVPVHLGAMSSTVRWQLEYWGENLNEGDVLVTNHPQAGGSHLPDITVITPVFRDG--KIVFFVASRGHHADIGGITPGSM 875
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  868 PPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQAPGKISGC---SGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQY 944
Cdd:PLN02666   876 PPFSKTIWEEGAAIKAFKLVEGGVFQEEGITKLLQAPGSDETApkiPGTRRLQDNLSDLRAQVAANQRGISLIKELIDEY 955
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  945 GLDVVQAYMGHIQANAELAVRDMLRAFGT--SRQARGLPLEVS----AKDHMDDGSPICLHVQINLNQGSAVFDFSGSGS 1018
Cdd:PLN02666   956 GLGTVQAYMGHVQANAELAVREMLKSVAArvSSESPTFGDGSSvtleAEDYMDDGSPIHLTLTIDRRKGSAVFDFEGTSP 1035
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1019 EVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACA 1098
Cdd:PLN02666  1036 EVYGNWNAPPAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIRIPPGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACA 1115
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1099 ASQGCMNNVTLGNARMGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRPGSGGRGRFRGGD 1178
Cdd:PLN02666  1116 CSQGCMNNLTFGDDTFGYYETIAGGAGAGPTWDGTSGVQCHMTNTRITDPEILERRYPVLLHRFGLREGSGGDGLHRGGD 1195
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1179 GVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPED 1258
Cdd:PLN02666  1196 GVVREIEFRRPVTVSILSERRVHAPRGLAGGGDGARGANLLIRKDGRRVNLGGKNTVHVEAGERLRILTPGGGGYGSKPS 1275
Hydantoinase_B pfam02538
Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts ...
735-1256 0e+00

Hydantoinase B/oxoprolinase; This family includes N-methylhydaintoinase B which converts hydantoin to N-carbamyl-amino acids, and 5-oxoprolinase EC:3.5.2.9 which catalyzes the formation of L-glutamate from 5-oxo-L-proline. These enzymes are part of the oxoprolinase family and are related to pfam01968.


Pssm-ID: 460583  Cd Length: 507  Bit Score: 687.28  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  735 PIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGaDLHPG 814
Cdd:pfam02538    1 PITLEVFRNRLMSIAEEMGRTLQRTAFSPNIKERLDFSCAIFDADGRLVAQAPHIPVHLGSMSFAVKAVIEYGG-DLRPG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  815 DVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVfQE 894
Cdd:pfam02538   80 DVFITNDPYAGGTHLPDITVITPVFHDG--ELVFFVASRGHHADIGGIVPGSMPPDATEIYQEGLRIPPVKLVRRGV-LN 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  895 EAVTEALqapgkisgCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAfgts 974
Cdd:pfam02538  157 EDVLRLL--------LANSRTPEDNLGDLKAQIAANRVGERRLLELIDEYGLDTVLAAMDEIQDYAERAVRAAIAA---- 224
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  975 rqargLPL-EVSAKDHMDDGSPICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGC 1053
Cdd:pfam02538  225 -----LPDgTYEAEDYLDDGVPIPIRVTVTIDGDEATVDFTGTSPQVPGNINAPLAVTHSAVIYALRCLVDPDIPLNAGC 299
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1054 LAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFG------ACAASQGCMNNVTLG-------NARMGYYETV 1120
Cdd:pfam02538  300 LRPIEVIAPEGSLLNPSPPAAVVGGNVETSQRIVDVVLGALAqalperVPAASQGTMNNLTFGgvdprggGRFFGYYETI 379
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1121 AGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELrpgsggrgrfrggDG-------------VVRELVFR 1187
Cdd:pfam02538  380 GGGSGARPGGDGLDGVHVHMTNTRNTPVEVLERRYPVLVERYEL-------------RPdsggagryrggdgVVREIEFL 446
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1188 E-EALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKdgrtvnlggKTSVTVYPGDAFCLHTPGGGGYGDP 1256
Cdd:pfam02538  447 ApDATVSILSERRVFPPWGLAGGEPGAPGRVNLGGK---------ATDVELKPGDRLRIETPGGGGYGDP 507
HyuA COG0145
N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport ...
10-725 0e+00

N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439915 [Multi-domain]  Cd Length: 678  Bit Score: 646.38  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240   10 FAIDRGGTFTDVFAQCPGGHVRVLKLLSeDPANYADAPTEGIRRILEQErgvllprgrPLDTSHIASIRMGTTVATNALL 89
Cdd:COG0145      1 VGVDVGGTFTDVVAVDEDGRLRTHKVLS-TPEDPSDGVLEGIRELLEDA---------GIPLAEIDLVVHGTTVATNALL 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240   90 ERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEvlyeevvevdervLLYRGEPgagspVKGCTGDLL---EIQQP 166
Cdd:COG0145     71 ERKGARTGLITTRGFRDVLEIGRQNRPDLYDLFIEKPE-------------PLVPRRL-----RFEVRERIDadgEVLTP 132
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  167 VDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARE-LGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTI 245
Cdd:COG0145    133 LDEAEVRAAARELRAAGVEAVAVCFLHSYRNPAHERRAAEILREeLPDVPVSLSSEVSPEIREYERTSTTVVNAYLSPIL 212
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  246 QRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFS--GSRAVLSGPAGGVVGySTTTYQLEGGQPVIGFDMGGTSTDVS 323
Cdd:COG0145    213 RRYLDRLEARLRERGFGGPLLIMQSNGGLASAEAAArrPVRTILSGPAGGVVG-AAALARAAGFDNVITFDMGGTSTDVS 291
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  324 RYA-GEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFF-RSGLFVVGPESAGAHPGPACYRKGGP-VTVTDANLVLGR 400
Cdd:COG0145    292 LIEdGEPERTTETEVAGYPVRVPMVDIHTVGAGGGSIAWVdAGGRLRVGPESAGADPGPACYGRGGTePTVTDANLVLGR 371
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  401 LLPASFPcifgpGEDQPLSPEASRKALEAVAMEVNsflasgpcpasqLSLEEVAMGFVRVANEAMCRPIRALTQARGHDP 480
Cdd:COG0145    372 LDPDNFL-----GGRMPLDVEAARAAIEKLADPLG------------LSVEEAAEGILRIANENMANAIRKVSVERGYDP 434
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  481 SAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLEEQCVD 560
Cdd:COG0145    435 RDFTLVAFGGAGPLHACALAEELGIPRVIVPPAAGVLSALGMLLADIRHDYVRSVEAPLDDADLAELNAAFAELEAEARA 514
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  561 ALQAQGFSRSQISTESFLHLRYQGTDCALMVSANQHPATTCSprAGDFGAAFVERYMREFGFIIPERSVVVDDVRVRGTG 640
Cdd:COG0145    515 ELAAEGVAAEDIRVERSADMRYAGQGHELTVPLPAGRLDAAD--LAALRAAFHAAHERRYGFALPDAPVEIVNLRVEAIG 592
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  641 RSG-LQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIETGDIRI 719
Cdd:COG0145    593 PVPkPELPRLPPGGDAAPAPKGTRPVYFDGGWVDTPVYDREALPPGDRIAGPAIIEEPDTTTVVPPGWRATVDAYGNLIL 672

                   ....*.
gi 1720385240  720 SVGAEA 725
Cdd:COG0145    673 TRAAAA 678
HyuB COG0146
N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit [Amino acid transport ...
729-1258 0e+00

N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 439916  Cd Length: 563  Bit Score: 600.59  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  729 IDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLG 808
Cdd:COG0146      1 LGTTVDPVTLEVIRNRLIAIAEEMGETLQRTAFSPNIKERLDFSCALFDADGRLVAQAPGIPVHLGSMPEAVKAVIERFG 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  809 A-DLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGqsRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLV 887
Cdd:COG0146     81 NdGIRPGDVFITNDPYLGGTHLPDITVVTPVFHDG--ELVGFVASRAHHADIGGIVPGSMPPDATEIFQEGLRIPPVKLV 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  888 QGGVFQEEAVTEALqapgkisgcSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDM 967
Cdd:COG0146    159 EAGELNEDVLRLIL---------ANVRTPDQNLGDLRAQIAANRVGERRLLELVERYGLDTVEAAMDELLDYAERAVRAA 229
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  968 LRAfgtsrqargLPL-EVSAKDHMDDGS----PICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCL 1042
Cdd:COG0146    230 IAA---------LPDgTYRAEDFLDDDGvgdePIKIKVTVTVKGDRITVDFTGTSPQVPGNINAPLAVTRAAVLYALRCL 300
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1043 VGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFG------ACAASQGCMNNVTLGNAR--- 1113
Cdd:COG0146    301 LDPDIPLNAGCLRPIEVIAPEGSILNPRYPAAVVAGNVETSQRVVDAVFGALAqalperVPAASQGTMNNLTFGGVDprg 380
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1114 --MGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELrpgsggrgrfrggDG------------ 1179
Cdd:COG0146    381 epFVYYETIGGGSGARPGGDGLDAVHTHMTNTRNTPVEVLEARYPVLVERYEL-------------RPdsggagkyrggl 447
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240 1180 -VVRELVFRE-EALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPE 1257
Cdd:COG0146    448 gVVREIRFLEpEMTVSLLGDRRRFPPWGLAGGGPGAPGRNVLVRGDGDEEELGGKATVPLQPGDVVVIETPGGGGYGDPL 527

                   .
gi 1720385240 1258 D 1258
Cdd:COG0146    528 E 528
Hydantoinase_A pfam01968
Hydantoinase/oxoprolinase; This family includes the enzymes hydantoinase and oxoprolinase EC:3. ...
231-513 5.76e-104

Hydantoinase/oxoprolinase; This family includes the enzymes hydantoinase and oxoprolinase EC:3.5.2.9. Both reactions involve the hydrolysis of 5-membered rings via hydrolysis of their internal imide bonds.


Pssm-ID: 396517 [Multi-domain]  Cd Length: 288  Bit Score: 330.79  E-value: 5.76e-104
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  231 RGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSG--SRAVLSGPAGGVVGYSTTTyQLEGGQ 308
Cdd:pfam01968    1 RTVTAVVNAYLAPIMREYLEGVEDSLEKVGSKAPVYVMQSDGGLVSIDEARKrpVETILSGPAAGVVGAAYTG-KLLGNK 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  309 PVIGFDMGGTSTDVSRYA-GEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRL-FFRSGLFVVGPESAGAHPGPACYRKG 386
Cdd:pfam01968   80 NLIGFDMGGTSTDISPIIdGEPEITTETEVAGYPTRLPRLDINTVGAGGGSILvSFLGGKVRVGPESAGADPGPACYRKG 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240  387 G-PVTVTDANLVLGRLLPASFPCIfgpgeDQPLSPEASRKALEAVAMEVNsflasgpcpasqLSLEEVAMGFVRVANEAM 465
Cdd:pfam01968  160 GtFPTVTDANLVLGRLNPEDFLGG-----DGKLDVEAARRAFEKLADPLN------------LGVEEVAEGIIRIANETM 222
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1720385240  466 CRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRH 513
Cdd:pfam01968  223 ARAVRLVTVERGYDPSEFVLVVFGGAGPQHAPALAEELGIKKVIVPPY 270
Hydant_A_N pfam05378
Hydantoinase/oxoprolinase N-terminal region; This family is found at the N-terminus of the ...
9-212 2.44e-58

Hydantoinase/oxoprolinase N-terminal region; This family is found at the N-terminus of the pfam01968 family.


Pssm-ID: 398834 [Multi-domain]  Cd Length: 176  Bit Score: 198.67  E-value: 2.44e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240    9 HFAIDRGGTFTDVFAQCPG-GHVRVLKLLSEDpanyaDAPTEGIRRILEQERGVLLPRgrpldTSHIASIRMGTTVATNA 87
Cdd:pfam05378    1 RIGIDVGGTFTDAVALDEGdGEVAVIKVLTTP-----DDPVEGIREALEELLGELGPR-----TGKVDTVRHGTTVATNA 70
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720385240   88 LLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPmpevlyeevvevderVLLY--RGEPGAGSPVKGctgdllEIQQ 165
Cdd:pfam05378   71 LLERKGARVGLITTKGFRDLLEIGRQNRPDLFDLYKP---------------LVLYelVVEVDERVDADG------EVLK 129
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1720385240  166 PVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELG 212
Cdd:pfam05378  130 PLDEEEVREALKALKDAGVEAIAVVLLHSYLNPEHELRVAEIAREEG 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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