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Conserved domains on  [gi|1720384786|ref|XP_030104539|]
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MYG1 exonuclease isoform X1 [Mus musculus]

Protein Classification

MYG1 family protein( domain architecture ID 10508566)

MYG1 family protein similar to Mus musculus MYG1 exonuclease, a 3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion

Gene Ontology:  GO:0016787
PubMed:  31081026

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UPF0160 pfam03690
Uncharacterized protein family (UPF0160); This family of proteins contains a large number of ...
10-251 3.20e-148

Uncharacterized protein family (UPF0160); This family of proteins contains a large number of metal binding residues. The patterns are suggestive of a phosphoesterase function. The conserved DHH motif may mean this family is related to pfam01368.


:

Pssm-ID: 461014  Cd Length: 315  Bit Score: 416.91  E-value: 3.20e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786  10 WQTKLSSAGLVYLHFGRKLLAQLLGTSEEDsvVDTIYDKMYENFVEEVDAVDNGISQWAEGEPRYAMTTTLSARVARLNP 89
Cdd:pfam03690  75 YNTKLSSAGLVYKHFGKEIIAKLLPVDDED--VELLYDKVYESFIEAIDAIDNGISQYDTGEPRYKINTTLSSRVGRLNP 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786  90 TWNQP--NQDTEAGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGgCPWKEHLYHLESE 167
Cdd:pfam03690 153 NWNEDetDEDEDERFEKASELVGEEFLDRVKYYAKSWLPARDIVEEALENRFEVDPSGRILVLDQF-CPWKEHLYELEKE 231
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786 168 LSPKVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGHHTREGALNMA 247
Cdd:pfam03690 232 LNIEGQILYVLYPDSSGKWRVQAVPVSPGSFESRKPLPEAWRGLRDEELSEVSGIPGCIFVHASGFIGGNKTREGALAMA 311

                  ....
gi 1720384786 248 RATL 251
Cdd:pfam03690 312 RKAL 315
 
Name Accession Description Interval E-value
UPF0160 pfam03690
Uncharacterized protein family (UPF0160); This family of proteins contains a large number of ...
10-251 3.20e-148

Uncharacterized protein family (UPF0160); This family of proteins contains a large number of metal binding residues. The patterns are suggestive of a phosphoesterase function. The conserved DHH motif may mean this family is related to pfam01368.


Pssm-ID: 461014  Cd Length: 315  Bit Score: 416.91  E-value: 3.20e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786  10 WQTKLSSAGLVYLHFGRKLLAQLLGTSEEDsvVDTIYDKMYENFVEEVDAVDNGISQWAEGEPRYAMTTTLSARVARLNP 89
Cdd:pfam03690  75 YNTKLSSAGLVYKHFGKEIIAKLLPVDDED--VELLYDKVYESFIEAIDAIDNGISQYDTGEPRYKINTTLSSRVGRLNP 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786  90 TWNQP--NQDTEAGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGgCPWKEHLYHLESE 167
Cdd:pfam03690 153 NWNEDetDEDEDERFEKASELVGEEFLDRVKYYAKSWLPARDIVEEALENRFEVDPSGRILVLDQF-CPWKEHLYELEKE 231
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786 168 LSPKVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGHHTREGALNMA 247
Cdd:pfam03690 232 LNIEGQILYVLYPDSSGKWRVQAVPVSPGSFESRKPLPEAWRGLRDEELSEVSGIPGCIFVHASGFIGGNKTREGALAMA 311

                  ....
gi 1720384786 248 RATL 251
Cdd:pfam03690 312 RKAL 315
 
Name Accession Description Interval E-value
UPF0160 pfam03690
Uncharacterized protein family (UPF0160); This family of proteins contains a large number of ...
10-251 3.20e-148

Uncharacterized protein family (UPF0160); This family of proteins contains a large number of metal binding residues. The patterns are suggestive of a phosphoesterase function. The conserved DHH motif may mean this family is related to pfam01368.


Pssm-ID: 461014  Cd Length: 315  Bit Score: 416.91  E-value: 3.20e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786  10 WQTKLSSAGLVYLHFGRKLLAQLLGTSEEDsvVDTIYDKMYENFVEEVDAVDNGISQWAEGEPRYAMTTTLSARVARLNP 89
Cdd:pfam03690  75 YNTKLSSAGLVYKHFGKEIIAKLLPVDDED--VELLYDKVYESFIEAIDAIDNGISQYDTGEPRYKINTTLSSRVGRLNP 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786  90 TWNQP--NQDTEAGFRRAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGgCPWKEHLYHLESE 167
Cdd:pfam03690 153 NWNEDetDEDEDERFEKASELVGEEFLDRVKYYAKSWLPARDIVEEALENRFEVDPSGRILVLDQF-CPWKEHLYELEKE 231
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720384786 168 LSPKVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDKALDQVSGIPGCIFVHASGFIGGHHTREGALNMA 247
Cdd:pfam03690 232 LNIEGQILYVLYPDSSGKWRVQAVPVSPGSFESRKPLPEAWRGLRDEELSEVSGIPGCIFVHASGFIGGNKTREGALAMA 311

                  ....
gi 1720384786 248 RATL 251
Cdd:pfam03690 312 RKAL 315
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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