NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1720383578|ref|XP_030104245|]
View 

oncostatin-M-specific receptor subunit beta isoform X2 [Mus musculus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 455-563 7.41e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 7.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 455 PLVNPKVEIpySTPNSFVLRW--PDYDSdfqaGFIKGYLVYVKSKEmqcNQPWErtllpdnsvlcKYDINGSETKTLTVE 532
Cdd:cd00063     3 PPTNLRVTD--VTSTSVTLSWtpPEDDG----GPITGYVVEYREKG---SGDWK-----------EVEVTPGSETSYTLT 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1720383578 533 NLQPESLYEFFVTPYTSAGPGPNETFTKVTT 563
Cdd:cd00063    63 GLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
fn3 pfam00041
Fibronectin type III domain;
165-246 7.28e-05

Fibronectin type III domain;


:

Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 42.02  E-value: 7.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 165 APQDVTLKIIGATKANMTWKVHSHGN----NYTLLCQVKLQYGEVIHEHNVSVHMSanYLFSDLDPDTKYKAFVRCASAN 240
Cdd:pfam00041   2 APSNLTVTDVTSTSLTVSWTPPPDGNgpitGYEVEYRPKNSGEPWNEITVPGTTTS--VTLTGLKPGTEYEVRVQAVNGG 79


                  ....*.
gi 1720383578 241 HFWKWS 246
Cdd:pfam00041  80 GEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 270-345 4.67e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


:

Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 36.82  E-value: 4.67e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720383578  270 VWSENGRRIVTLFWKPLLKSQANGKIISYniVVENEAKPTESEHYCVWAPALSTNLSlDLQP---YKIRITANNSMGAS 345
Cdd:smart00060   8 RVTDVTSTSVTLSWEPPPDDGITGYIVGY--RVEYREEGSEWKEVNVTPSSTSYTLT-GLKPgteYEFRVRAVNGAGEG 83
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 455-563 7.41e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 7.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 455 PLVNPKVEIpySTPNSFVLRW--PDYDSdfqaGFIKGYLVYVKSKEmqcNQPWErtllpdnsvlcKYDINGSETKTLTVE 532
Cdd:cd00063     3 PPTNLRVTD--VTSTSVTLSWtpPEDDG----GPITGYVVEYREKG---SGDWK-----------EVEVTPGSETSYTLT 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1720383578 533 NLQPESLYEFFVTPYTSAGPGPNETFTKVTT 563
Cdd:cd00063    63 GLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
fn3 pfam00041
Fibronectin type III domain;
165-246 7.28e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 42.02  E-value: 7.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 165 APQDVTLKIIGATKANMTWKVHSHGN----NYTLLCQVKLQYGEVIHEHNVSVHMSanYLFSDLDPDTKYKAFVRCASAN 240
Cdd:pfam00041   2 APSNLTVTDVTSTSLTVSWTPPPDGNgpitGYEVEYRPKNSGEPWNEITVPGTTTS--VTLTGLKPGTEYEVRVQAVNGG 79


                  ....*.
gi 1720383578 241 HFWKWS 246
Cdd:pfam00041  80 GEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 455-553 1.15e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.45  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578  455 PLVNPKVEIPYSTPNSFVLRW--PDYDSDfqagfiKGYLVYVKSKEMQCNQPWERTLLPDNsvlckydingseTKTLTVE 532
Cdd:smart00060   1 PSPPSNLRVTDVTSTSVTLSWepPPDDGI------TGYIVGYRVEYREEGSEWKEVNVTPS------------STSYTLT 62

                           90       100
                   ....*....|....*....|.
gi 1720383578  533 NLQPESLYEFFVTPYTSAGPG 553
Cdd:smart00060  63 GLKPGTEYEFRVRAVNGAGEG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 163-255 2.13e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 40.94  E-value: 2.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 163 PKAPQDVTLKIIGATKANMTWKVHSHGN----NYTLlcQVKLQYGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCAS 238
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEDDGgpitGYVV--EYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|....*...
gi 1720383578 239 ANHfwkWSDW-TQKEFST 255
Cdd:cd00063    79 GGG---ESPPsESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 163-236 5.36e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 39.52  E-value: 5.36e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720383578  163 PKAPQDVTLKIIGATKANMTWKVHSHGNNYTLLCQVKLQYGEVIHE-HNVSVHMSAN-YLFSDLDPDTKYKAFVRC 236
Cdd:smart00060   1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEwKEVNVTPSSTsYTLTGLKPGTEYEFRVRA 76
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 270-345 4.67e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 36.82  E-value: 4.67e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720383578  270 VWSENGRRIVTLFWKPLLKSQANGKIISYniVVENEAKPTESEHYCVWAPALSTNLSlDLQP---YKIRITANNSMGAS 345
Cdd:smart00060   8 RVTDVTSTSVTLSWEPPPDDGITGYIVGY--RVEYREEGSEWKEVNVTPSSTSYTLT-GLKPgteYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
467-554 5.84e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 36.62  E-value: 5.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 467 TPNSFVLRW---PDYDSDfqagfIKGYLVYVKSKEMQcNQPWERTLLPDnsvlckydingseTKTLTVENLQPESLYEFF 543
Cdd:pfam00041  12 TSTSLTVSWtppPDGNGP-----ITGYEVEYRPKNSG-EPWNEITVPGT-------------TTSVTLTGLKPGTEYEVR 72

                          90
                  ....*....|.
gi 1720383578 544 VTPYTSAGPGP 554
Cdd:pfam00041  73 VQAVNGGGEGP 83
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 455-563 7.41e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 7.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 455 PLVNPKVEIpySTPNSFVLRW--PDYDSdfqaGFIKGYLVYVKSKEmqcNQPWErtllpdnsvlcKYDINGSETKTLTVE 532
Cdd:cd00063     3 PPTNLRVTD--VTSTSVTLSWtpPEDDG----GPITGYVVEYREKG---SGDWK-----------EVEVTPGSETSYTLT 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1720383578 533 NLQPESLYEFFVTPYTSAGPGPNETFTKVTT 563
Cdd:cd00063    63 GLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
fn3 pfam00041
Fibronectin type III domain;
165-246 7.28e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 42.02  E-value: 7.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 165 APQDVTLKIIGATKANMTWKVHSHGN----NYTLLCQVKLQYGEVIHEHNVSVHMSanYLFSDLDPDTKYKAFVRCASAN 240
Cdd:pfam00041   2 APSNLTVTDVTSTSLTVSWTPPPDGNgpitGYEVEYRPKNSGEPWNEITVPGTTTS--VTLTGLKPGTEYEVRVQAVNGG 79


                  ....*.
gi 1720383578 241 HFWKWS 246
Cdd:pfam00041  80 GEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 455-553 1.15e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.45  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578  455 PLVNPKVEIPYSTPNSFVLRW--PDYDSDfqagfiKGYLVYVKSKEMQCNQPWERTLLPDNsvlckydingseTKTLTVE 532
Cdd:smart00060   1 PSPPSNLRVTDVTSTSVTLSWepPPDDGI------TGYIVGYRVEYREEGSEWKEVNVTPS------------STSYTLT 62

                           90       100
                   ....*....|....*....|.
gi 1720383578  533 NLQPESLYEFFVTPYTSAGPG 553
Cdd:smart00060  63 GLKPGTEYEFRVRAVNGAGEG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 163-255 2.13e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 40.94  E-value: 2.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 163 PKAPQDVTLKIIGATKANMTWKVHSHGN----NYTLlcQVKLQYGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCAS 238
Cdd:cd00063     1 PSPPTNLRVTDVTSTSVTLSWTPPEDDGgpitGYVV--EYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90
                  ....*....|....*...
gi 1720383578 239 ANHfwkWSDW-TQKEFST 255
Cdd:cd00063    79 GGG---ESPPsESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 163-236 5.36e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 39.52  E-value: 5.36e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720383578  163 PKAPQDVTLKIIGATKANMTWKVHSHGNNYTLLCQVKLQYGEVIHE-HNVSVHMSAN-YLFSDLDPDTKYKAFVRC 236
Cdd:smart00060   1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEwKEVNVTPSSTsYTLTGLKPGTEYEFRVRA 76
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 270-345 4.67e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 36.82  E-value: 4.67e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720383578  270 VWSENGRRIVTLFWKPLLKSQANGKIISYniVVENEAKPTESEHYCVWAPALSTNLSlDLQP---YKIRITANNSMGAS 345
Cdd:smart00060   8 RVTDVTSTSVTLSWEPPPDDGITGYIVGY--RVEYREEGSEWKEVNVTPSSTSYTLT-GLKPgteYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
467-554 5.84e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 36.62  E-value: 5.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720383578 467 TPNSFVLRW---PDYDSDfqagfIKGYLVYVKSKEMQcNQPWERTLLPDnsvlckydingseTKTLTVENLQPESLYEFF 543
Cdd:pfam00041  12 TSTSLTVSWtppPDGNGP-----ITGYEVEYRPKNSG-EPWNEITVPGT-------------TTSVTLTGLKPGTEYEVR 72

                          90
                  ....*....|.
gi 1720383578 544 VTPYTSAGPGP 554
Cdd:pfam00041  73 VQAVNGGGEGP 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH