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Conserved domains on  [gi|1720422361|ref|XP_030098385|]
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ataxin-2-like protein isoform X15 [Mus musculus]

Protein Classification

SM-ATX and LsmAD domain-containing protein( domain architecture ID 13860551)

SM-ATX and LsmAD domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 35-108 2.96e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


:

Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 2.96e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422361  35 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 108
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 176-238 1.39e-17

LsmAD domain; This domain is found associated with Lsm domain.


:

Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.39e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422361 176 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 238
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 super family cl37801
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 669-888 1.42e-10

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


The actual alignment was detected with superfamily member pfam09770:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.44  E-value: 1.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 669 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 734
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 735 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 792
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 793 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 872
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335

                         250
                  ....*....|....*.
gi 1720422361 873 PHGFTNMAHVTQAHVQ 888
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 315-860 3.10e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.49  E-value: 3.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  315 GGPSRMSPKAQRPLRGAKTL--SSPSNRPSGEA--------SVPPTSAAlPFLPVGRMYPPRSPKSAAPAPVSASCPEPP 384
Cdd:PHA03247  2549 GDPPPPLPPAAPPAAPDRSVppPRPAPRPSEPAvtsrarrpDAPPQSAR-PRAPVDDRGDPRGPAPPSPLPPDTHAPDPP 2627

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  385 I--GSAVASSASIPVTSSVVDPGAGSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleel 462
Cdd:PHA03247  2628 PpsPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR------ 2686

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  463 rkfgaqfKLQPSSSPETGL-DPFPsrilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeql 541
Cdd:PHA03247  2687 -------AARPTVGSLTSLaDPPP----------------------PPPTPEPA------------PHALVSATPLP--- 2722

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  542 PAPCPSQTGSPPVGLikgdekeeGPVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSG 621
Cdd:PHA03247  2723 PGPAAARQASPALPA--------APAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRR 2782

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  622 LYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatP 701
Cdd:PHA03247  2783 LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------P 2845

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  702 YSSYIPYNPQQFPGQPAMMQPMahyPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSY 779
Cdd:PHA03247  2846 PPPSLPLGGSVAPGGDVRRRPP---SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQ 2922

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  780 PHHATqlhghQPQPATTPtgsQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFP 858
Cdd:PHA03247  2923 PPPPP-----QPQPPPPP---PPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTP 2994


                   ..
gi 1720422361  859 QP 860
Cdd:PHA03247  2995 PL 2996
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 35-108 2.96e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 2.96e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422361  35 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 108
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 176-238 1.39e-17

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.39e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422361 176 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 238
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 669-888 1.42e-10

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.44  E-value: 1.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 669 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 734
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 735 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 792
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 793 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 872
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335

                         250
                  ....*....|....*.
gi 1720422361 873 PHGFTNMAHVTQAHVQ 888
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 PHA03247
large tegument protein UL36; Provisional
 315-860 3.10e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.49  E-value: 3.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  315 GGPSRMSPKAQRPLRGAKTL--SSPSNRPSGEA--------SVPPTSAAlPFLPVGRMYPPRSPKSAAPAPVSASCPEPP 384
Cdd:PHA03247  2549 GDPPPPLPPAAPPAAPDRSVppPRPAPRPSEPAvtsrarrpDAPPQSAR-PRAPVDDRGDPRGPAPPSPLPPDTHAPDPP 2627

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  385 I--GSAVASSASIPVTSSVVDPGAGSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleel 462
Cdd:PHA03247  2628 PpsPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR------ 2686

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  463 rkfgaqfKLQPSSSPETGL-DPFPsrilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeql 541
Cdd:PHA03247  2687 -------AARPTVGSLTSLaDPPP----------------------PPPTPEPA------------PHALVSATPLP--- 2722

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  542 PAPCPSQTGSPPVGLikgdekeeGPVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSG 621
Cdd:PHA03247  2723 PGPAAARQASPALPA--------APAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRR 2782

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  622 LYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatP 701
Cdd:PHA03247  2783 LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------P 2845

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  702 YSSYIPYNPQQFPGQPAMMQPMahyPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSY 779
Cdd:PHA03247  2846 PPPSLPLGGSVAPGGDVRRRPP---SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQ 2922

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  780 PHHATqlhghQPQPATTPtgsQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFP 858
Cdd:PHA03247  2923 PPPPP-----QPQPPPPP---PPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTP 2994


                   ..
gi 1720422361  859 QP 860
Cdd:PHA03247  2995 PL 2996
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
788-863 1.39e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.54  E-value: 1.39e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720422361 788 GHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAphlgSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 863
Cdd:PRK14971  389 APQPSAAAAASPSPSQSSAAAQPSAPQSATQP----AGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPV 460
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 35-108 2.96e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 2.96e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422361  35 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 108
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 176-238 1.39e-17

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.39e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422361 176 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 238
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 669-888 1.42e-10

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.44  E-value: 1.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 669 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 734
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 735 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 792
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 793 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 872
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335

                         250
                  ....*....|....*.
gi 1720422361 873 PHGFTNMAHVTQAHVQ 888
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 PHA03247
large tegument protein UL36; Provisional
 315-860 3.10e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.49  E-value: 3.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  315 GGPSRMSPKAQRPLRGAKTL--SSPSNRPSGEA--------SVPPTSAAlPFLPVGRMYPPRSPKSAAPAPVSASCPEPP 384
Cdd:PHA03247  2549 GDPPPPLPPAAPPAAPDRSVppPRPAPRPSEPAvtsrarrpDAPPQSAR-PRAPVDDRGDPRGPAPPSPLPPDTHAPDPP 2627

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  385 I--GSAVASSASIPVTSSVVDPGAGSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleel 462
Cdd:PHA03247  2628 PpsPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR------ 2686

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  463 rkfgaqfKLQPSSSPETGL-DPFPsrilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeql 541
Cdd:PHA03247  2687 -------AARPTVGSLTSLaDPPP----------------------PPPTPEPA------------PHALVSATPLP--- 2722

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  542 PAPCPSQTGSPPVGLikgdekeeGPVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSG 621
Cdd:PHA03247  2723 PGPAAARQASPALPA--------APAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRR 2782

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  622 LYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatP 701
Cdd:PHA03247  2783 LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------P 2845

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  702 YSSYIPYNPQQFPGQPAMMQPMahyPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSY 779
Cdd:PHA03247  2846 PPPSLPLGGSVAPGGDVRRRPP---SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQ 2922

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  780 PHHATqlhghQPQPATTPtgsQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFP 858
Cdd:PHA03247  2923 PPPPP-----QPQPPPPP---PPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTP 2994


                   ..
gi 1720422361  859 QP 860
Cdd:PHA03247  2995 PL 2996
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 709-955 5.91e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 53.50  E-value: 5.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 709 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSG----SHPQAI----VSSS------TPQYPAAEQPTPQALYAT 774
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyekyKEPEPIpdlqVDASlwgvapKKAAAPAPAPQPAAQPAS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 775 VHQSYPHHAT------QLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP 848
Cdd:pfam09770 186 LPAPSRKMMSleeveaAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 849 SaQSPQSSFPQPAAVYA-IHPHQQLPHGFTNMAHVTQAHVQTGVtaappphpgaphppQVMLLHPPQGHGGPPQGAVPPS 927
Cdd:pfam09770 266 L-QRPQSPQPDPAQPSIqPQAQQFHQQPPPVPVQPTQILQNPNR--------------LSAARVGYPQNPQPGVQPAPAH 330

                         250       260
                  ....*....|....*....|....*...
gi 1720422361 928 GVPALSASTPSPYPYIGHPQVQSHPSQQ 955
Cdd:pfam09770 331 QAHRQQGSFGRQAPIITHPQQLAQLSEE 358
PHA03247 PHA03247
large tegument protein UL36; Provisional
 252-647 7.16e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 7.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  252 PSLVSREGKYIPLPQRVRegPRGGVRCSSSRGGRPGLSSLPPrGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRG- 330
Cdd:PHA03247  2580 PAVTSRARRPDAPPQSAR--PRAPVDDRGDPRGPAPPSPLPP-DTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDp 2656

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  331 ----------------AKTLSSPSNRPSGEASVPP----TSAALPFLPVGRMYP------PRSPKSAAPAPVSASCPEPP 384
Cdd:PHA03247  2657 apgrvsrprrarrlgrAAQASSPPQRPRRRAARPTvgslTSLADPPPPPPTPEPaphalvSATPLPPGPAAARQASPALP 2736

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  385 IGSAVASSASIPVTSSVVDPGAGSISPASPKLSLTPTDvkelPTKEPSRNLEAQELARIAGKVPGLQNEQKRFQLEELRK 464
Cdd:PHA03247  2737 AAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAA----PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVL 2812

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  465 fGAQFKLQPSSSPETGLDPFPSrilkeeakgkekevdGLLTSDPMGSPVSSKTESIldkEDKVPMAGVGGTEGPEQLPAP 544
Cdd:PHA03247  2813 -APAAALPPAASPAGPLPPPTS---------------AQPTAPPPPPGPPPPSLPL---GGSVAPGGDVRRRPPSRSPAA 2873

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  545 CPSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVL----TAGQS 620
Cdd:PHA03247  2874 KPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLApttdPAGAG 2953

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1720422361  621 ----GLYSPQYISYIPQIHMGPAVQAPQMYP 647
Cdd:PHA03247  2954 epsgAVPQPWLGALVPGRVAVPRFRVPQPAP 2984
PHA03247 PHA03247
large tegument protein UL36; Provisional
 508-957 7.16e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 7.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  508 PMGSPVSSKTESILDKEDKVPMAGVGGTEGPEQLPAPCPSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTK 587
Cdd:PHA03247  2589 PDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRAR 2668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  588 PLLSVNKSTSTPTSPGPRTHSTPSIPVltagqSGLYSPQyisyipqihmgPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 667
Cdd:PHA03247  2669 RLGRAAQASSPPQRPRRRAARPTVGSL-----TSLADPP-----------PPPPTPEPAPHALVSATPLPPGPAAARQAS 2732

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  668 LPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPqqfpgqPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGS 747
Cdd:PHA03247  2733 PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP------AAGPPRRLTRPAVASLSESRESLPSPWDPAD 2806

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  748 HPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQlhghQPQPATTPTGS---------QPQSQHAAPSPVQHQAGQ 818
Cdd:PHA03247  2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG----PPPPSLPLGGSvapggdvrrRPPSRSPAAKPAAPARPP 2882

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  819 APHLGSGQPQQNlyhPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPhgftnmahvtqahvqtgvTAAPPPH 898
Cdd:PHA03247  2883 VRRLARPAVSRS---TESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPP------------------PPPRPQP 2941

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720422361  899 PGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQVQSHPSQQLP 957
Cdd:PHA03247  2942 PLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHS 3000
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 286-613 1.15e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.22  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 286 PGLSSLPPRGPHHlDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKtlsSPSNRPSGEASVPPTSAALPFLPVGRMYP- 364
Cdd:PTZ00449  514 PEASGLPPKAPGD-KEGEEGEHEDSKESDEPKEGGKPGETKEGEVGK---KPGPAKEHKPSKIPTLSKKPEFPKDPKHPk 589

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 365 -PRSPKSAApAPVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLT---PTDVKELPTKEPSRnleaqel 440
Cdd:PTZ00449  590 dPEEPKKPK-RPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSperPEGPKIIKSPKPPK------- 661

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 441 ariAGKVPglqneqkrFQLEELRKFGAQFKLQPSSSPETGLDPFPSRILKEEAKGKEKEVDGLLTSDPMG-SPVSSKTES 519
Cdd:PTZ00449  662 ---SPKPP--------FDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPlPPKLPRDEE 730

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 520 ILDKEDKVPMAgvggtegpeqlPAPCPSQTGSPPVGL------IKGDEKEEGPVTEQVKKSTLNPNAKEfnPTKPLLSVN 593
Cdd:PTZ00449  731 FPFEPIGDPDA-----------EQPDDIEFFTPPEEErtffheTPADTPLPDILAEEFKEEDIHAETGE--PDEAMKRPD 797

                         330       340
                  ....*....|....*....|.
gi 1720422361 594 KSTS-TPTSPGprTHstPSIP 613
Cdd:PTZ00449  798 SPSEhEDKPPG--DH--PSLP 814
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
788-863 1.39e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.54  E-value: 1.39e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720422361 788 GHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAphlgSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 863
Cdd:PRK14971  389 APQPSAAAAASPSPSQSSAAAQPSAPQSATQP----AGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPV 460
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 759-961 1.62e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.80  E-value: 1.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 759 QYPAAEQPTPQALYATVHQSYPHHATQLHGHQPQPATT---------------------PTGSQPQSQHAAPSPVQHQAG 817
Cdd:pfam09770 105 QQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTgyekykepepipdlqvdaslwGVAPKKAAAPAPAPQPAAQPA 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 818 QAPHLG-------------SGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQ 884
Cdd:pfam09770 185 SLPAPSrkmmsleeveaamRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVT 264

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720422361 885 AHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQV--QSHPSQQLPFHPP 961
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQPAPahQAHRQQGSFGRQA 343
PRK10927 PRK10927
cell division protein FtsN;
759-862 3.30e-04

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 43.90  E-value: 3.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 759 QYPAAEQPTPQalyatvHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALT 838
Cdd:PRK10927  144 QTPEQRQQTLQ------RQRQAQQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHT 217

                          90       100
                  ....*....|....*....|....*
gi 1720422361 839 GTPPSLP-PGPSAQSPQSsfPQPAA 862
Cdd:PRK10927  218 TAQSKPQqAAPVTRAADA--PKPTA 240
Herpes_TAF50 pfam03326
Herpesvirus transcription activation factor (transactivator); This family includes EBV BRLF1 ...
 538-834 4.90e-04

Herpesvirus transcription activation factor (transactivator); This family includes EBV BRLF1 and similar ORF 50 proteins from other herpesviruses.


Pssm-ID: 308764 [Multi-domain]  Cd Length: 568  Bit Score: 43.92  E-value: 4.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 538 PEQLPAPCPSQTGSPP----VGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 613
Cdd:pfam03326 269 PQRLQAPGFSRSTSRPargqTAQYFLAAQQHGVVSLFPSTATLVPIAGSTGVTEVVSYGHNSTSPSSTPCPSTAVTEADH 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 614 VLTAGQSGLYSPQYISYipQIHMGPAVQAPQMYPYPvsnsvpgqqGKYRGAKGsLPPQRSDQHQPAsappmmqAAAAAAG 693
Cdd:pfam03326 349 QTEPEVPWIATAHQESD--QRPIGPGPEKPTFLPPV---------GGKQFFQG-LRDSRSTSFLTA-------PEATSAI 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 694 PPLVAATPYSSYIPYNPQQFPGQPammqpmahypsqpvfapmlqSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYA 773
Cdd:pfam03326 410 SDVFQGTEVCQPKRIRALHPPGSP--------------------SANRPLPSSLAPTPTGPVHEPGSSLTPATVPQPLDA 469

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720422361 774 T--VHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP 834
Cdd:pfam03326 470 ApvATPEASHELQPPDEETPQPLDEDQALCGQQDASHPPPRGQLDELTTTLESMTEDLNLDSP 532
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 711-868 5.29e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.92  E-value: 5.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  711 QQFPG-QPAMMQPMAHypSQPVFAPMlqsnPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQLHGH 789
Cdd:PRK10263   709 QRYSGeQPAGANPFSL--DDFEFSPM----KALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQ 782

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720422361  790 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQnlyhpgaltgtpPSLPPGPSAQSPQSSFPQPAAVYaIHP 868
Cdd:PRK10263   783 QPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQ------------PVAPQPQYQQPQQPVAPQPQDTL-LHP 848
PHA03247 PHA03247
large tegument protein UL36; Provisional
 467-960 1.94e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  467 AQFKLQPSSSPETGLDPFPSrilKEEAKGKEKEVDGLLTSDPMGSPVSSKTESILDKEDKVPMAGVGGTEG--PEQLPAP 544
Cdd:PHA03247  2486 ARFPFAAGAAPDPGGGGPPD---PDAPPAPSRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPplPPAAPPA 2562

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  545 CPSQTGSPPvglikgdEKEEGPVTEQVKKSTLNPNAKEfNPTKPLLSVNKSTSTPTSPGPrTHSTPSIPVLTAGQSGLYS 624
Cdd:PHA03247  2563 APDRSVPPP-------RPAPRPSEPAVTSRARRPDAPP-QSARPRAPVDDRGDPRGPAPP-SPLPPDTHAPDPPPPSPSP 2633

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  625 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAAGPPLVAAT 700
Cdd:PHA03247  2634 AANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRaRRLGRAAQASSPPQRPRRRAarpTVGSLTSLADPPPPPPTPEPAPH 2713

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  701 PYSSYIPYNP-QQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAeQPTPQALYATVhqsy 779
Cdd:PHA03247  2714 ALVSATPLPPgPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA-GPPRRLTRPAV---- 2788

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  780 phhatqlhghqpQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPsaqsPQSSFPQ 859
Cdd:PHA03247  2789 ------------ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP----PPPSLPL 2852

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  860 PAAVYAIHP-HQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQvmllhPPQGHGGPPQGAVPPSGVPalsaSTPS 938
Cdd:PHA03247  2853 GGSVAPGGDvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-----PPDQPERPPQPQAPPPPQP----QPQP 2923

                          490       500
                   ....*....|....*....|..
gi 1720422361  939 PYPYIGHPQVQSHPSQQLPFHP 960
Cdd:PHA03247  2924 PPPPQPQPPPPPPPRPQPPLAP 2945
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 306-472 4.36e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.85  E-value: 4.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 306 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPsnRPSGEASVPPTSAAlPFLPVGRMYPPRSPKSAAPAPVSASCPEPPI 385
Cdd:PRK14951  374 APAEKKTPARPEAAAPAAAPVAQAAAAPAPAA--APAAAASAPAAPPA-AAPPAPVAAPAAAAPAAAPAAAPAAVALAPA 450

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 386 GSAVASS--ASIPVTSSV---VDPGAGSISPASPKLSLTPTD--------VKELPTKEPSRNLeAQELAriagkvpgLQN 452
Cdd:PRK14951  451 PPAQAAPetVAIPVRVAPepaVASAAPAPAAAPAAARLTPTEegdvwhatVQQLAAAEAITAL-ARELA--------LQS 521

                         170       180
                  ....*....|....*....|....*....
gi 1720422361 453 E---------QKRFQLEELRKFGAQFKLQ 472
Cdd:PRK14951  522 ElvardgdqwLLRVERESLNQPGARERLR 550
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
327-469 4.50e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 40.91  E-value: 4.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 327 PLRGAKTLSSPSNrpSGEASVPPTSAAlpflPVGRMYPPRS---PKSAAPAPVSASCPEPPIGSaVASSASIPVTSSVVD 403
Cdd:PRK14971  371 GGRGPKQHIKPVF--TQPAAAPQPSAA----AAASPSPSQSsaaAQPSAPQSATQPAGTPPTVS-VDPPAAVPVNPPSTA 443

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422361 404 PGAGSISPASPKLSLTPTDV--KELPTKEPSRNLEAQELARIAGKVPGLQNEQkrFQLEELRKFGAQF 469
Cdd:PRK14971  444 PQAVRPAQFKEEKKIPVSKVssLGPSTLRPIQEKAEQATGNIKEAPTGTQKEI--FTEEDLQYYWQEF 509
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 247-432 4.51e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.83  E-value: 4.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 247 SGRESPSLVSREGKYIPLPQRVREGPRGGvRCSSSRGGRPglSSLP-----PRGP----HHLDNSSPGPGSEARGINGGP 317
Cdd:PTZ00449  531 EGEHEDSKESDEPKEGGKPGETKEGEVGK-KPGPAKEHKP--SKIPtlskkPEFPkdpkHPKDPEEPKKPKRPRSAQRPT 607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 318 SRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAALPFLPVGrmypPRSPKSAAPaPVSascPEPPIG----------- 386
Cdd:PTZ00449  608 RPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEG----PKIIKSPKP-PKS---PKPPFDpkfkekfyddy 679

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1720422361 387 SAVASSASIPVTSSVVDPGAGSISPAS-PKLSLTP-TDVKELPTKEPS 432
Cdd:PTZ00449  680 LDAAAKSKETKTTVVLDESFESILKETlPETPGTPfTTPRPLPPKLPR 727
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
301-441 4.52e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 4.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 301 NSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSA------ALPFLPVGRMYPPRSPKSA-AP 373
Cdd:PRK12323  371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAparrspAPEALAAARQASARGPGGApAP 450

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422361 374 APVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLTPTdVKELPTKEPSRNLEAQELA 441
Cdd:PRK12323  451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPP-WEELPPEFASPAPAQPDAA 517
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
669-862 4.76e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.63  E-value: 4.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 669 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 748
Cdd:PRK12323  365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 749 PQAIVSSSTP-------QYPAAEQPTPQALYATVHQSYPHHATQlhgHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 821
Cdd:PRK12323  445 GGAPAPAPAPaaapaaaARPAAAGPRPVAAAAAAAPARAAPAAA---PAPADDDPPPWEELPPEFASPAPAQPDAAPAGW 521

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1720422361 822 LGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 862
Cdd:PRK12323  522 VAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVA 562
PHA03247 PHA03247
large tegument protein UL36; Provisional
 546-962 4.91e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 4.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  546 PSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSV----NKSTSTPTSPGPRTHSTPSIPVLTAGQSg 621
Cdd:PHA03247  2489 PFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRMLTwirgLEELASDDAGDPPPPLPPAAPPAAPDRS- 2567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  622 LYSPQYISYIPqihmGPAVQA----PQMYPYPVSNSVPGQ-QGKYRG--AKGSLPPQRSDQHQPASAPPMMQAAAAAAGP 694
Cdd:PHA03247  2568 VPPPRPAPRPS----EPAVTSrarrPDAPPQSARPRAPVDdRGDPRGpaPPSPLPPDTHAPDPPPPSPSPAANEPDPHPP 2643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  695 PLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPvfapmlqsnPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYAT 774
Cdd:PHA03247  2644 PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP---------PQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHA 2714

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  775 VHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNlyHPGALTGTPP---SLPPGPSAQ 851
Cdd:PHA03247  2715 LVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPA--PPAAPAAGPPrrlTRPAVASLS 2792

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  852 SPQSSFPQPAAVyAIHPHQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQVMLLhpPQGHGGPPQGAV---PPSG 928
Cdd:PHA03247  2793 ESRESLPSPWDP-ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL--PLGGSVAPGGDVrrrPPSR 2869

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1720422361  929 VPALSASTPS--PYPYIGHPQVqSHPSQQLPFHPPG 962
Cdd:PHA03247  2870 SPAAKPAAPArpPVRRLARPAV-SRSTESFALPPDQ 2904
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 651-962 6.38e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 40.52  E-value: 6.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 651 SNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQ 729
Cdd:pfam03154 145 SPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPqGSPATSQPPNQTQST 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 730 PVFAPMLQSNPRMltsgsHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHatqlhghqpqpatTPTGSQPQSQHAAP 809
Cdd:pfam03154 225 AAPHTLIQQTPTL-----HPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLH-------------GQMPPMPHSLQTGP 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361 810 SPVQHQAGQAPHLGSGQPQQNLYHPGaltgtPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQ-LPHgftnmAHVTQAHVQ 888
Cdd:pfam03154 287 SHMQHPVPPQPFPLTPQSSQSQVPPG-----PSPAAPGQSQQRIHTPPSQSQLQSQQPPREQpLPP-----APLSMPHIK 356

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720422361 889 TGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSAST---PSPYPYIGHPQVQSHPSQQLPFHPPG 962
Cdd:pfam03154 357 PPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLSThhpPSAHPPPLQLMPQSQQLPPPPAQPPV 433
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 239-433 7.27e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 7.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  239 HSAVQRQGSGRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGP---------HHLDNSSPGPGSE 309
Cdd:PHA03307   171 QAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAaddagasssDSSSSESSGCGWG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422361  310 ARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAALPflPVGRMYPPRSPKSAAPAPVSASCPEPPIGSAV 389
Cdd:PHA03307   251 PENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSP--SPSPSSPGSGPAPSSPRASSSSSSSRESSSSS 328

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1720422361  390 ASSASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEPSR 433
Cdd:PHA03307   329 TSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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